Abstract: Containers for the storage of red blood cell compositions are disclosed. The container walls are made of a plastic composition that includes a polymeric material and at least one extractable agent that includes a terephthalate ester in an amount effective to suppress hemolysis in red blood cells.

Abstract: A method of recovering white blood cells from a leukoreduction filter, the method comprising providing a solution comprising a sugar, flowing a volume of the solution through a leukoreduction filter containing captured white blood cells, and collecting elute from the leukoreduction filter, wherein the elute comprises the solution and recovered white blood cells.

Abstract: Filter media, filter devices and methods of making filter media are disclosed. The filter media includes a coating on at least a portion of said outer surface. The coating may be polymeric composition having a molecular chain that includes segments of non-polar groups and segments of at least one of polar groups or segments of ionic groups.

Abstract: Containers for the storage of red blood cell compositions are disclosed. The container walls are made of a plastic composition that includes a polymeric material and at least one extractable agent that includes a terephthalate ester in an amount effective to suppress hemolysis in red blood cells.

Abstract: Containers for the storage of red blood cell compositions are disclosed. The container walls are made of a plastic composition that includes a polymeric material and at least one extractable agent that includes a terephthalate ester in an amount effective to suppress hemolysis in red blood cells.

Abstract: Methods and systems for removing leukocytes from a biological fluid are disclosed. The methods and systems include a device that has a magnetic substrate coated with one or more polymeric materials that have an adhesion or adsorption affinity for leukocytes.

Abstract: A method of recovering white blood cells from a leukoreduction filter, the method comprising providing a solution comprising a sugar, flowing a volume of the solution through a leukoreduction filter containing captured white blood cells, and collecting elute from the leukoreduction filter, wherein the elute comprises the solution and recovered white blood cells.

Abstract: Methods and systems for removing leukocytes from a biological fluid are disclosed. The methods and systems include a chamber containing particles to which the leukocytes adhere. Such particles may carry an electrostatic charge. In one example, the particles comprise a polymer having an acid number of 5 or greater.

Abstract: Filter media, filter devices and methods of making filter media are disclosed. The filter media includes a coating on at least a portion of said outer surface. The coating may be polymeric composition having a molecular chain that includes segments of non-polar groups and segments of at least one of polar groups or segments of ionic groups.

Abstract: A system is provided for separating a bodily fluid, such as blood, into two or more constituent parts. The system is configured to cooperate with a fluid flow circuit including a spinning membrane-type fluid separation chamber having a housing, with a fluid inlet port and at least one fluid outlet port. A rotor is positioned within the housing so as to define a gap between the rotor and an inside surface of the housing, with the rotor being rotatable relative to the housing about an axis. A membrane is mounted on the rotor and/or on the inside surface of the housing and faces the gap to separate bodily fluid within the housing into two or more constituent parts. The membrane includes an anti-thrombogenic material, which may be either incorporated into the material of the membrane or coated onto at least a portion of the membrane.

Abstract: Methods and systems for removing leukocytes from a biological fluid are disclosed. The methods and systems include a chamber containing particles to which the leukocytes adhere. Such particles may carry an electrostatic charge. In one example, the particles comprise a polymer having an acid number of 5 or greater.

Abstract: Filter media, filter devices and methods of making filter media are disclosed. The filter media includes a coating on at least a portion of said outer surface. The coating may be polymeric composition having a molecular chain that includes segments of non-polar groups and segments of at least one of polar groups or segments of ionic groups.

Abstract: Containers for the storage of red blood cell compositions are disclosed. The container walls are made of a plastic composition that includes a polymeric material and at least one extractable agent that includes a terephthalate ester in an amount effective to suppress hemolysis in red blood cells.

Abstract: Methods and systems for removing leukocytes from a biological fluid are disclosed. The methods and systems include a device that has a magnetic substrate coated with one or more polymeric materials that have an adhesion or adsorption affinity for leukocytes.

Abstract: The present invention provides a transparent or colorless coating comprising a heat responsive material that increases in opacity when exposed to heat. An example of a heat responsive material is an inorganic compound or an organic resin. The present invention further provides a coating composition comprising a carrier and a heat responsive material. The coating can further include additives such as an adhesion promoter, a defoamer, a crosslinking agent, a plasticizer, a humectant, a pH adjuster, a biocide, a co-solvent, a surface tension modifier, and/or a combination thereof. The present invention further provides a method for creating a mark on a substrate comprising providing to the substrate the transparent coating to obtain a coated substrate and exposing a selected area of the coated substrate to heat, e.g., a laser, to create the mark. The present invention further provides substrates suitable for laser marking.

Abstract: The present invention provides a laser markable coating composition comprising a colorant and a polymeric material whose opacity changes substantially irreversibly when exposed to heat. The composition may further include a carrier, an adhesion promoter, an energy transfer agent, an opaque polymeric material, and one or more binder resins. The present invention further provides a heat responsive colorant particle comprising a colorant and a polymeric material whose opacity changes substantially irreversibly when exposed to heat. A laser beam can be used to provide the heat. An example of a suitable polymeric material that irreversibly changes in opacity is a styrene/acrylic microsphere. An example of a suitable colorant is carbon black pigment. An example of an energy transfer agent is fumed silica. An example of an adhesion promoter is an oxidized polyethylene. An example of a suitable carrier is water.

Abstract: The present invention provides a transparent or colorless coating comprising a heat responsive material that increases in opacity when exposed to heat. An example of a heat responsive material is a silicate or a titanate. The present invention further provides a coating composition comprising a carrier and a heat responsive material. The coating can further include additives such as adhesion promoters, surface tension modifying agents, crosslinking agents, or plasticizers. The present invention further provides a method for creating a mark on a substrate comprising providing to the substrate the transparent coating to obtain a coated substrate and exposing a selected area of the coated substrate to heat, e.g., a laser, to create the mark. The present invention further provides substrates suitable for laser marking.

Abstract: The present invention provides a transparent coating comprising a resin and a heat responsive material that increases in opacity when exposed to heat. Preferably, the transparent coating is free or substantially free of a pigment or dye. An example of a heat responsive material is a carbohydrate. The present invention further provides a coating composition comprising a solvent, a resin, and a heat responsive material that increases in opacity when exposed to heat. The present invention further provides a method for creating a mark on a substrate comprising providing to the substrate the transparent coating to obtain a coated substrate and exposing a selected area of the coated substrate to heat to create the mark. The substrates can be marked with a laser.

Abstract: The present invention provides a laser markable coating composition comprising a colorant and a polymeric material whose opacity changes substantially irreversibly when exposed to heat. The composition may further include a carrier, an adhesion promoter, an energy transfer agent, an opaque polymeric material, and one or more binder resins. The present invention further provides a heat responsive colorant particle comprising a colorant and a polymeric material whose opacity changes substantially irreversibly when exposed to heat. A laser beam can be used to provide the heat. An example of a suitable polymeric material that irreversibly changes in opacity is a styrene/acrylic microsphere. An example of a suitable colorant is carbon black pigment. An example of an energy transfer agent is fumed silica. An example of an adhesion promoter is an oxidized polyethylene. An example of a suitable carrier is water.

Abstract: Surface treated pigment particles made by contacting a dispersion of pigment particles with a halosilane or organohalosilane, elevating the temperature to form a siloxane on the surface of the particles and recovering the surface treated particles as a presscake or as dry particles.