Patents by Inventor Yoshinori Beppu
Yoshinori Beppu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230054264Abstract: A glycated protein is disclosed having a glycated side chain amino group of lysine, the glycated protein having a glycated side chain amino group of at least one of lysine at position 160 or lysine at position 189 of an amino acid sequence represented by SEQ ID NO: 1 of: (a1) a protein having the amino acid sequence represented by SEQ ID NO: 1; (a2) a protein having an amino acid sequence wherein 1 to 9 amino acids are deleted, substituted, inserted, and/or added in a region other than at least one of lysine at position 160 or lysine at position 189; and (a3) a protein having an amino acid sequence having at least 98% identity with the amino acid sequence represented by SEQ ID NO: 1, in which at least one of an amino acid at position 160 or an amino acid at position 189 is lysine.Type: ApplicationFiled: December 15, 2020Publication date: February 23, 2023Applicant: SUNTORY HOLDINGS LIMITEDInventors: Keiko Iwasa, Yoshinori Beppu, Koichi Nakahara, Yoshihide Matsuo, Yohei Fujita
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Publication number: 20230048747Abstract: The present invention aims to provide a non-alcoholic beer-taste beverage with an enhanced rich flavor and a reduced sour flavor using a grain-derived raw material. The present invention relates to a non-alcoholic beer-taste beverage having an alcohol content of less than 1.0%, the non-alcoholic beer-taste beverage containing a glycated protein which is a grain-derived protein, has a glycated amino group of lysine, and has a molecular weight of 35 to 50 kDa.Type: ApplicationFiled: December 15, 2020Publication date: February 16, 2023Applicant: SUNTORY HOLDINGS LIMITEDInventors: Keiko Iwasa, Yoshinori Beppu, Yoshihide Matsuo, Yohei Fujita
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Patent number: 11382911Abstract: A diketopiperazine mixture suitable for mixing with a food or drink and a method for producing the mixture. High-temperature and high-pressure treatment of plant peptides in a liquid allows production of a plant extract containing a high concentration of diketopiperazines including cyclo-leucyl-leucine and cyclo-leucyl-phenylalanine. Diketopiperazines having excellent flavor derived from a plant natural product and can produce a food or drink provided with the functions of the diketopiperazines by directly mixing the diketopiperazines with the food or drink.Type: GrantFiled: July 19, 2019Date of Patent: July 12, 2022Assignee: SUNTORY HOLDINGS LIMITEDInventors: Kenji Yamamoto, Yoshinori Beppu, Koichi Nakahara, Tomonori Suzuki, Soichiro Shima, Yuka Murakami
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Patent number: 11207258Abstract: It is an object of the present invention to provide a capsule comprising a functional substance and having good shape stability and a good feeling of use. A method for producing a capsule, comprising steps of mixing gelatin and a functional substance; adding a carbodiimide crosslinking agent to crosslink the gelatin with the carbodiimide crosslinking agent; solidifying the crosslinked gelatin; and grinding the solidified gelatin.Type: GrantFiled: January 25, 2017Date of Patent: December 28, 2021Assignee: SUNTORY HOLDINGS LIMITEDInventors: Yoshinori Beppu, Yoshihide Matsuo
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Patent number: 10668885Abstract: A side airbag device for a rear seat relating to the technique of the present disclosure includes: an airbag module that is provided at an interior of a side garnish that is disposed between a vehicle body side portion and a vehicle transverse direction outer side of a seatback of a rear seat; a tubular flow regulating cloth that is provided at an interior of a side airbag of the airbag module, at a periphery of an inflator; and an airbag door that is provided at the side garnish, and that has a hinge portion and a tear portion at a periphery thereof, and that is pushed by the tubular flow regulating cloth when gas is generated from the inflator, wherein the tubular flow regulating cloth has openings at both ends thereof, and has exhaust holes in a peripheral wall thereof.Type: GrantFiled: November 17, 2017Date of Patent: June 2, 2020Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, AUTOLIV DEVELOPMENT ABInventors: Seiji Hioda, Yoshinori Beppu, Atsushi Yamada, Takuya Sudo
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Publication number: 20190336569Abstract: A diketopiperazine mixture suitable for mixing with a food or drink and a method for producing the mixture. High-temperature and high-pressure treatment of plant peptides in a liquid allows production of a plant extract containing a high concentration of diketopiperazines including cyclo-leucyl-leucine and cyclo-leucyl-phenylalanine. Diketopiperazines having excellent flavor derived from a plant natural product and can produce a food or drink provided with the functions of the diketopiperazines by directly mixing the diketopiperazines with the food or drink.Type: ApplicationFiled: July 19, 2019Publication date: November 7, 2019Applicant: SUNTORY HOLDINGS LIMITEDInventors: Kenji Yamamoto, Yoshinori Beppu, Koichi Nakahara, Tomonori Suzuki, Soichiro Shima, Yuka Murakami
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Publication number: 20190029940Abstract: It is an object of the present invention to provide a capsule comprising a functional substance and having good shape stability and a good feeling of use. A method for producing a capsule, comprising steps of mixing gelatin and a functional substance; adding a carbodiimide crosslinking agent to crosslink the gelatin with the carbodiimide crosslinking agent; solidifying the crosslinked gelatin; and grinding the solidified gelatin.Type: ApplicationFiled: January 25, 2017Publication date: January 31, 2019Applicant: SUNTORY HOLDINGS LIMITEDInventors: Yoshinori BEPPU, Yoshihide MATSUO
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Publication number: 20180194318Abstract: A side airbag device for a rear seat relating to the technique of the present disclosure includes: an airbag module that is provided at an interior of a side garnish that is disposed between a vehicle body side portion and a vehicle transverse direction outer side of a seatback of a rear seat; a tubular flow regulating cloth that is provided at an interior of a side airbag of the airbag module, at a periphery of an inflator; and an airbag door that is provided at the side garnish, and that has a hinge portion and a tear portion at a periphery thereof, and that is pushed by the tubular flow regulating cloth when gas is generated from the inflator, wherein the tubular flow regulating cloth has openings at both ends thereof, and has exhaust holes in a peripheral wall thereof.Type: ApplicationFiled: November 17, 2017Publication date: July 12, 2018Applicants: TOYOTA JIDOSHA KABUSHIKI KAISHA, AUTOLIV DEVELOPMENT ABInventors: Seiji Hioda, Yoshinori Beppu, Atsushi Yamada, Takuya Sudo
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Publication number: 20170143701Abstract: Provided is a safe carbohydrate metabolism-ameliorating agent having an excellent carbohydrate metabolism-ameliorating action, and a safe GLP-1 secretion accelerator having an excellent GLP-1 secretion-accelerating action. The carbohydrate metabolism-ameliorating agent or GLP-1 secretion accelerator according to the present invention, which contains a specific cyclic dipeptide or a salt thereof as an active ingredient, is advantageous in that it has an excellent carbohydrate metabolism-ameliorating action, and that it is safe and can be ingested for a long period.Type: ApplicationFiled: June 11, 2015Publication date: May 25, 2017Applicant: SUNTORY HOLDINGS LIMITEDInventors: Toshihide Suzuki, Kenji Yamamoto, Yoshinori Beppu, Hiroshi Watanabe
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Patent number: 9650415Abstract: A uric acid-lowering agent containing, as an active ingredient, a tyrosine-containing cyclic dipeptide selected from the group consisting of cyclotryptophanyltyrosine, cycloseryltyrosine, cycloprolyltyrosine, cyclotyrosylglycine, cyclotyrosyltyrosine, cyclophenylalanyltyrosine, cycloleucyltyrosine, cyclolysyltyrosine, cyclohistidyltyrosine, cycloalanyltyrosine, cycloglutamyltyrosine, cyclovalyltyrosine, cycloisoleucyltyrosine, cyclothreonyltyrosine, cycloaspartyltyrosine, cycloasparaginyltyrosine, cycloglutaminyltyrosine, cycloarginyltyrosine, cyclomethionyltyrosine, and cyclotyrosylcysteine, or a salt thereof. The uric acid-lowering agent of the present invention has an excellent action of lowering a uric acid level, and the uric acid-lowering agent is useful in, for example, prevention or treatment of hyperuricemia, gout or the like.Type: GrantFiled: June 20, 2014Date of Patent: May 16, 2017Assignee: Suntory Holdings LimitedInventors: Toshihide Suzuki, Shinya Fukizawa, Yoshinori Beppu, Hiroshi Watanabe
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Publication number: 20170129919Abstract: A cyclic dipeptide-containing composition containing each of tyrosine-containing cyclic dipeptides selected from the group consisting of cyclotryptophanyltyrosine, cycloseryltyrosine, cycloprolyltyrosine, cyclotyrosylglycine, cyclotyrosyltyrosine, cyclophenylalanyltyrosine, cycloleucyltyrosine, cyclolysyltyrosine, cyclohistidyltyrosine, cycloalanyltyrosine, cycloglutamyltyrosine, cyclovalyltyrosine, cycloisoleucyltyrosine, cyclothreonyltyrosine, cycloaspartyltyrosine, cycloasparaginyltyrosine, cycloglutaminyltyrosine, cycloarginyltyrosine, and cyclomethionyltyrosine, or a salt thereof in a specified amount. The cyclic dipeptide-containing composition of the present invention has an excellent action of lowering a uric acid level, and the cyclic dipeptide-containing composition is useful in, for example, prevention or treatment of hyperuricemia, gout or the like.Type: ApplicationFiled: February 13, 2015Publication date: May 11, 2017Applicant: Suntory Holdings LimitedInventors: Toshihide Suzuki, Shinya Fukizawa, Yoshinori Beppu, Hiroshi Watanabe
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Publication number: 20170114030Abstract: Provided is a composition having an excellent physiological effect. Inventors have found that a composition in which the total amount of cyclic dipeptides including amino acids as constituent units, or salts thereof, is greater than or equal to a specific amount has the effect of improving sugar metabolism, and have also found that the sugar metabolism improvement effect is achieved by including given contents of specific cyclic dipeptides. This composition is advantageous in that it has an excellent sugar metabolism improvement effect, and that it can be taken in safely for a long period of time.Type: ApplicationFiled: December 17, 2014Publication date: April 27, 2017Applicant: SUNTORY HOLDINGS LIMITEDInventors: Toshihide Suzuki, Kenji Yamamoto, Yoshinori Beppu, Hiroshi Watanabe
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Patent number: 9623073Abstract: The present invention aims to provide antidepressants which are free from the problem of side effects and are excellent in safety. The present invention also aims to provide learning motivation improvers which are useful for improvement of learning motivation and can be ingested continuously. The present invention provides antidepressants and learning motivation improvers, each comprising a cyclic dipeptide with the 2,5-diketopiperazine structure as an active ingredient.Type: GrantFiled: November 9, 2015Date of Patent: April 18, 2017Assignees: SUNTORY HOLDINGS LIMITED, CEREBOS PACIFIC LIMITEDInventors: Nobuo Tsuruoka, Yoshinori Beppu, Hirofumi Kouda, Hiroshi Watanabe
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Publication number: 20160159858Abstract: A uric acid-lowering agent containing, as an active ingredient, a tyrosine-containing cyclic dipeptide selected from the group consisting of cyclotryptophanyltyrosine, cycloseryltyrosine, cycloprolyltyrosine, cyclotyrosylglycine, cyclotyrosyltyrosine, cyclophenylalanyltyrosine, cycloleucyltyrosine, cyclolysyltyrosine, cyclohistidyltyrosine, cycloalanyltyrosine, cycloglutamyltyrosine, cyclovalyltyrosine, cycloisoleucyltyrosine, cyclothreonyltyrosine, cycloaspartyltyrosine, cycloasparaginyltyrosine, cycloglutaminyltyrosine, cycloarginyltyrosine, cyclomethionyltyrosine, and cyclotyrosylcysteine, or a salt thereof. The uric acid-lowering agent of the present invention has an excellent action of lowering a uric acid level, and the uric acid-lowering agent is useful in, for example, prevention or treatment of hyperuricemia, gout or the like.Type: ApplicationFiled: June 20, 2014Publication date: June 9, 2016Applicant: SUNTORY HOLDINGS LIMITEDInventors: Toshihide Suzuki, Shinya Fukizawa, Yoshinori Beppu, Hiroshi Watanabe
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Publication number: 20160106130Abstract: Provided are a diketopiperazine mixture suitable for mixing with a food or drink and a method for producing the mixture. High-temperature and high-pressure treatment of plant peptides in a liquid allows production of a plant extract containing a high concentration of diketopiperazines including cyclo-leucyl-leucine and cyclo-leucyl-phenylalanine. The present invention can provide diketopiperazines having excellent flavor derived from a plant natural product and can produce a food or drink provided with the functions of the diketopiperazines by directly mixing the diketopiperazines with the food or drink.Type: ApplicationFiled: June 10, 2014Publication date: April 21, 2016Applicants: SUNTORY HOLDINGS LIMITED, SUNTORY HOLDINGS LIMITEDInventors: Kenji Yamamoto, Yoshinori Beppu, Koichi Nakahara, Tomonori Suzuki, Soichiro Shima, Yuka Murakami
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Publication number: 20160058831Abstract: The present invention aims to provide antidepressants which are free from the problem of side effects and are excellent in safety. The present invention also aims to provide learning motivation improvers which are useful for improvement of learning motivation and can be ingested continuously. The present invention provides antidepressants and learning motivation improvers, each comprising a cyclic dipeptide with the 2,5-diketopiperazine structure as an active ingredient.Type: ApplicationFiled: November 9, 2015Publication date: March 3, 2016Applicants: SUNTORY HOLDINGS LIMITED, CEREBOS PACIFIC LIMITEDInventors: Nobuo TSURUOKA, Yoshinori BEPPU, Hirofumi KOUDA, Hiroshi WATANABE
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Patent number: 9139151Abstract: This airbag device includes a first protective cover and a second protective cover which store and protect an airbag. The airbag has a tab formed between the first protective cover and the second protective cover so as to protrude outward approximately in parallel with a longitudinal direction of the airbag. The tab has one end connected to the first protective cover and the other end connected to the second protective cover.Type: GrantFiled: March 15, 2013Date of Patent: September 22, 2015Assignee: AUTOLIV DEVELOPMENT ABInventor: Yoshinori Beppu
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Publication number: 20150054266Abstract: This airbag device includes a first protective cover and a second protective cover which store and protect an airbag. The airbag has a tab formed between the first protective cover and the second protective cover so as to protrude outward approximately in parallel with a longitudinal direction of the airbag. The tab has one end connected to the first protective cover and the other end connected to the second protective cover.Type: ApplicationFiled: March 15, 2013Publication date: February 26, 2015Inventor: Yoshinori Beppu
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Patent number: 8669267Abstract: There is provided a pharmaceutical agent, food, or beverage for treating or preventing a disease or condition that can be ameliorated by inhibiting serotonin reuptake, comprising a clinically-effective amount of (1S,3S)-1-methyl-1,2,3,4-tetrahydro-?-carboline-3-carboxylic acid.Type: GrantFiled: August 6, 2009Date of Patent: March 11, 2014Assignee: Suntory Holdings LimitedInventors: Yoshinori Beppu, Nobuo Tsuruoka, Hajime Komura
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Publication number: 20130331344Abstract: The present invention aims to provide antidepressants which are free from the problem of side effects and are excellent in safety. The present invention also aims to provide learning motivation improvers which are useful for improvement of learning motivation and can be ingested continuously. The present invention provides antidepressants and learning motivation improvers, each comprising a cyclic dipeptide with the 2,5-diketopiperazine structure as an active ingredient.Type: ApplicationFiled: August 13, 2013Publication date: December 12, 2013Applicants: CEREBOS PACIFIC LIMITED, SUNTORY HOLDINGS LIMITEDInventors: Nobuo TSURUOKA, Yoshinori BEPPU, Hirofumi KOUDA, Hiroshi WATANABE