Patents by Inventor Yoshitaka Yasuhara

Yoshitaka Yasuhara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Animal with gene hypoexpression
    Patent number: 7462757
    Abstract: The present invention relates to non-human animal embryonic stem cells in which a lecithin:cholesterol acyltransferase-like lysophospholipase endogenous gene is inactivated; non-human animals deficient in expression of LLPL gene; methods of screening for prophylactics and/or therapeutic drug using the cells or the animals; and prophylactics and/or therapeutic drug obtainable by the screening. The non-human animal ES cells of the invention in which their LLPL gene is inactivated are very useful in creating non-human animals deficient in expression of LLPL gene. The LLPL expression deficient non-human animals of the invention can be disease models for such diseases caused by insufficiency of the biological activities of LLPL since the animals lack various biological activities inducible by LLPL.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: December 9, 2008
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Tomoko Satomi, Ryuichi Tozawa, Mitsugu Nakata, Yoshitaka Yasuhara, Yoshio Taniyama
  • Animal with gene hypoexpression
    Publication number: 20040143862
    Abstract: The present invention relates to non-human animal embryonic stem cells in which a lecithin:cholesterol acyltransferase-like lysophospholipase endogenous gene is inactivated; non-human animals deficient in expression of LLPL gene; methods of screening for prophylactics and/or therapeutic drug using the cells or the animals; and prophylactics and/or therapeutic drug obtainable by the screening.
    Type: Application
    Filed: November 21, 2003
    Publication date: July 22, 2004
    Inventors: Tomoko Satomi, Mitsugu Tozawa, Mitsugu Nakata, Yoshitaka Yasuhara, Yoshio Taniyama