Patents by Inventor Yoshiyuki Shikata

Yoshiyuki Shikata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6080755
    Abstract: Disclosed are diazabicyclo compounds of formula (I) ##STR1## in which R.sup.1 is a substituted or unsubstituted lower alkyl, lower alkenyl or lower alkynyl; R.sup.2 is a hydroxy; R.sup.3 is a lower alkoxycarbonyl; R.sup.4 and R.sup.7 are hydrogens or substituted or unsubstituted phenyl groups; R.sup.5 and R.sup.6 are hydrogens or lower alkyl groups; or pharmaceutically acceptable salts thereof, having cardioprotective activity. Also disclosed are methods of treating cardiovascular disease using a compound of formula (I) or pharmaceutically acceptable compositions comprising the compound of formula (I).
    Type: Grant
    Filed: February 3, 1998
    Date of Patent: June 27, 2000
    Assignee: Wyeth Lederle Japan, Ltd.
    Inventors: Hiroshi Matsunaga, Souiti Kaneda, Hisashi Shimidzu, Yoshiyuki Shikata, Toshio Kumagai
  • Patent number: 5130483
    Abstract: Isoprenoid derivatives represented by the general formula (I) ##STR1## wherein R represents a hydrogen atom or a lower alkyl group, X represents --CH.sub.2 --, --O-- or --NH--, n represents number of the double bond in trans-configuration and is 1 or 2, and m is an integer from 0 to 3.The compounds have a 5-lipoxygenase-inhibiting activity and are useful as a therapeutic agent for such diseases as allergy, nephritis, hepatitis, rheumatism and gastric ulcer.
    Type: Grant
    Filed: May 18, 1990
    Date of Patent: July 14, 1992
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Hiroyuki Ohnishi, Shingo Koyama, Ryoichi Nanba, Syozo Miyaoka, Akira Masuda, Yoshiyuki Shikata, Hideto Ushijima, Seiitsu Murota
  • Patent number: 5037837
    Abstract: Novel phenoxypropylamine derivative having the formula (I) ##STR1## wherein R.sub.1 and R.sub.2 represent a hydrogen atom, a hydroxy group, a lower alkyl group or a lower alkoxy group, and R.sub.3 and R.sub.4 represent a lower alkyl group, or R.sub.3 and R.sub.4 taken together represent a group having the formula (CH.sub.2).sub.m wherein m represents 4 or 5, and n represents an integer of from 2 to 6 or a pharmaceutically acceptable salt thereof.The compounds are useful as a 5-lipoxygenase inhibitor and an antiulcer agent.
    Type: Grant
    Filed: November 1, 1990
    Date of Patent: August 6, 1991
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Yoshiyuki Shikata, Ryoichi Nanba, Isamu Endo, Masashi Isozaki, Tadashi Okumura, Masazumi Miyakoshi, Shingo Koyama