Patents by Inventor Young Ha Kim

Young Ha Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030215483
    Abstract: Disclosed is a biocompatible medical material and porous scaffold for use in tissue engineering, made from a biodegradable glycolide/&egr;-caprolactone copolymer. The medical material and porous scaffold have excellent mechanical properties such as flexibility and elasticity, and appropriate hydrolytic properties. Due to its superior mechanical properties including elasticity, flexibility and appropriate biodegradation time, it can be used effectively as a porous scaffold for tissue cell culture reproduction such as for artificial skin, blood vessels, dental matrix and wound coverings.
    Type: Application
    Filed: May 13, 2002
    Publication date: November 20, 2003
    Inventors: Young-Ha Kim, Soo-Hyun Kim, Ki-Dong Park, Sung-Won Choi, Soo-Hong Lee, Il-Keun Kwon
  • Patent number: 6617027
    Abstract: Disclosed are surface-modified medical metallic materials and preparation thereof. The medical metallic material is prepared by coating a gold or silver thin layer onto a base metal, adsorbing a polyfunctional sulfur compound onto the gold or silver thin layer, and chemically bonding a biologically active material such as heparin or estradiol to the functional group of the sulfur compound. The biologically active material is firmly bonded to the base metal via the sulfur compound. Being significantly improved in antithrombogenicity and biocompatibility, the metallic materials are suitable for use in various implants, including stents, artificial cardiac valves and catheters.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: September 9, 2003
    Assignee: Korea Institute of Science and Technology
    Inventors: Young Ha Kim, Ki Dong Park, Soo Hyun Kim, Won Kyu Lee, Hyun Chul Goo
  • Publication number: 20030139567
    Abstract: Disclosed is a sequentially ordered biodegradable lactide (or glycolide or lactide/glycolide)/&egr;-caprolactone multi-block copolymers having proper degradation properties and enhanced mechanical properties such as flexibility and elasticity and a process for the preparation thereof.
    Type: Application
    Filed: November 14, 2002
    Publication date: July 24, 2003
    Inventors: Young Ha Kim, Soo Hyun Kim, Soo-Hong Lee, Oju Jeon
  • Patent number: 6476156
    Abstract: The present invention relates to polyethyleneglycol/polylactide(or polyglycolide or polycaprolactone)/polyethyleneglycol triblock copolymers with an enhanced reactivity, and process for their preparation. More specifically, the present invention is directed to triblock copolymers that are obtained by the process comprising the step of synthesizing a polylactide(or polyglycolide or polycaprolactone) having hydroxy groups at both ends and the step of coupling said polylactide with polyethyleneglycol having an acylhalide group of a high reactivity at one of its ends, and the process for preparing the same Since the triblock copolymer according to the present invention has an ester structure with good biocompatibility, it can be applied extensively for biomaterials used in tissue engineering, in a matrix that slowly releases drugs, etc.
    Type: Grant
    Filed: February 7, 2001
    Date of Patent: November 5, 2002
    Assignee: Korea Institute of Science and Technology
    Inventors: Young Ha Kim, Soo Hyun Kim, Ki Dong Park, Soo-Hong Lee
  • Publication number: 20020161134
    Abstract: The present invention relates to polyethyleneglycol/polylactide (or polyglycolide or polycaprolactone)/polyethyleneglycol triblock copolymers with an enhanced reactivity, and process for their preparation.
    Type: Application
    Filed: February 7, 2001
    Publication date: October 31, 2002
    Applicant: Korea Institute of Science and Technology
    Inventors: Young Ha Kim, Soo Hyun Kim, Ki Dong Park, Soo-Hong Lee
  • Patent number: 6440565
    Abstract: A surface-modified medical metallic material, which comprise a metallic substrate; a thin film of gold or silver coated on the surface of said substrate; a functional sulfur compound adsorbed on said thin film; and a sulfonated poly(ethylene oxide) (PEO) derivative chemically bonded to functional groups of said sulfur compound, and a method for the preparation thereof are disclosed. It is also disclosed a stent, a cardiac valve and a catheter prepared from the surface-modified metal material.
    Type: Grant
    Filed: September 15, 2000
    Date of Patent: August 27, 2002
    Assignee: Korea Institute of Science and Technology
    Inventors: Young-Ha Kim, Ki-Dong Park, Dong-Jun Ahn, Soo-Hyun Kim, Won-Kyu Lee
  • Publication number: 20010037144
    Abstract: Disclosed are surface-modified medical metallic materials and preparation thereof. The medical metallic material is prepared by coating a gold or silver thin layer onto a base metal, adsorbing a polyfunctional sulfur compound onto the gold or silver thin layer, and chemically bonding a biologically active material such as heparin or estradiol to the functional group of the sulfur compound. The biologically active material is firmly bonded to the base metal via the sulfur compound. Being significantly improved in antithrombogenicity and biocompatibility, the metallic materials are suitable for use in various implants, including stents, artificial cardiac valves and catheters.
    Type: Application
    Filed: March 26, 2001
    Publication date: November 1, 2001
    Inventors: Young Ha Kim, Ki Dong Park, Soo Hyun Kim, Won Kyu Lee, Hyun Chul Goo
  • Patent number: 5697972
    Abstract: The specification describes an invention of calcification resistant bioprosthetic heart valves which can be used for a long term, and have good blood compatibility and in vivo stability, and have high calcification resistance. The bioprosthetic heart valves of the invention can be prepared by binding sulfonated polyethylene oxide (PEO) derivatives covalently to the tissue. The valves have an anionic effect equal to that of chondroitin sulfate, space filling effect, and blocking effect of the carboxyl group of collagen which has been known as one factor of the calcium deposition,. In particular, the present method has better advantages in view of calcification resistance than any other conventional methods, because it suppresses thrombosis and embolism and decreases incidence of infection.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 16, 1997
    Assignee: Korea Institute of Science and Technology
    Inventors: Young Ha Kim, Ki Dong Park, Dong Keun Han, Hack Joo Kim
  • Patent number: 5216087
    Abstract: Novel sulfonated polyethyleneoxide-substituted polymers having improved blood compatibility are provided. The polymers are produced by substituting a polymeric substrate having active sites of amide or acid amide group, such as polyurethane, polyamide and polyacrylamide, with sulfonated polyethyleneoxide [PEO--(SO.sub.3 H).sub.n ].The polymers according to the present invention are valuable as construction materials of the artificial organs for the circulatory system in contact with blood, such as artificial hearts, artificial blood vessels, artificial kidneys, etc.
    Type: Grant
    Filed: May 17, 1991
    Date of Patent: June 1, 1993
    Assignee: Korea Institute of Science and Technology
    Inventors: Young-Ha Kim, Seo-Young Jeong, Kwang-Duk Ahn, Dong-Keun Han
  • Patent number: 5116361
    Abstract: Novel sulfonated polyethyleneoxide-substituted polymers having improved blood compatibility are provided. The polymers are produced by substituting a polymeric substrate having active sites of amide or acid amide group, such as polyurethane, polyamide and polyacrylamide, with sulfonated polyethyleneoxide PEO-SO.sub.3 H.The polymers according to the present invention are valuable as construction materials of the artificial organs for the circulatory system in contact with blood, such as artificial hearts, artificial blood vessels, artificial kidneys, etc.
    Type: Grant
    Filed: June 7, 1990
    Date of Patent: May 26, 1992
    Assignee: Korea Institute of Science and Technology
    Inventors: Young-Ha Kim, Seo-Young Jeong, Kwang-Duk Ahn, Dong-Keun Han