Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; a reflective layer disposed on the substrate; a light source passing through the reflective layer and disposed on the substrate; a resin layer disposed on the reflective layer; and an optical pattern disposed on the resin layer, wherein the light source includes a first light emitting device and a second light emitting device spaced apart from the first light emitting device, wherein the optical pattern may include a first optical pattern disposed on an upper portion of the first light emitting device and a second optical pattern disposed on an upper portion of the second light emitting device, and the first optical pattern and the second optical pattern may have different areas.

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; a plurality of light sources disposed on the substrate; and a resin layer disposed on the substrate and the plurality of light sources, and a first reflective layer disposed on the resin layer, wherein the resin layer includes an exit surface facing the light sources, the exit surface of the resin layer includes a plurality of convex portions, the plurality of light sources are disposed on a virtual curve, wherein a straight line passing through centers of the first and second light sources adjacent to each other and the centers of each convex portion may be disposed at an obtuse angle with respect to a straight line connecting the adjacent first and second light sources.

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; light sources disposed on the substrate; and a resin layer disposed on the substrate and the light sources. a first reflective layer disposed on the resin layer, wherein the resin layer includes an exit surface facing the light sources, and the exit surface of the resin layer includes convex portions facing each of the light sources and recess portions respectively disposed between the plurality of convex portions, concave surfaces disposed in each of the plurality of recess portions may have a curvature, and a radius of curvature of the concave surfaces may increase in one direction.

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; a light source including a plurality of light emitting devices disposed on the substrate; a resin layer disposed on the substrate; and a first diffusion layer disposed on the resin layer, wherein the resin layer includes a first resin portion disposed on the light source, and a second resin portion adjacent to the first resin portion and disposed on the substrate. The upper surface of the first resin portion has an inclination and is spaced apart from the first diffusion layer, the second resin portion includes a material different from that of the first resin portion, and the second resin portion based on the upper surface of the substrate. The height of the upper surface may be greater than the lowermost height of the upper surface of the first resin portion.

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; a plurality of light sources disposed on the substrate; and a resin layer disposed on the substrate and the plurality of light sources, and a first reflective layer disposed on the resin layer, wherein the resin layer includes an exit surface facing the light sources, the exit surface of the resin layer includes a plurality of convex portions, the plurality of light sources are disposed on a virtual curve, wherein a straight line passing through centers of the first and second light sources adjacent to each other and the centers of each convex portion may be disposed at an obtuse angle with respect to a straight line connecting the adjacent first and second light sources.

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; a reflective layer disposed on the substrate; a light source passing through the reflective layer and disposed on the substrate; a resin layer disposed on the reflective layer; and an optical pattern disposed on the resin layer, wherein the light source includes a first light emitting device and a second light emitting device spaced apart from the first light emitting device, wherein the optical pattern may include a first optical pattern disposed on an upper portion of the first light emitting device and a second optical pattern disposed on an upper portion of the second light emitting device, and the first optical pattern and the second optical pattern may have different areas.

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; a light source including a plurality of light emitting devices disposed on the substrate; a resin layer disposed on the substrate; and a first diffusion layer disposed on the resin layer, wherein the resin layer includes a first resin portion disposed on the light source, and a second resin portion adjacent to the first resin portion and disposed on the substrate. The upper surface of the first resin portion has an inclination and is spaced apart from the first diffusion layer, the second resin portion includes a material different from that of the first resin portion, and the second resin portion based on the upper surface of the substrate. The height of the upper surface may be greater than the lowermost height of the upper surface of the first resin portion.

Abstract: The present invention relates to a high-sensitivity nanoplasmonic biosensor for detecting autophagy markers by plasmon resonance effect, a manufacturing method therefor, and an autophagy marker detection method using same. The nanoplasmonic biosensor according to the present invention can detect LC3, which is an autophagy marker, by using a plasmon resonance effect even without an additional marker, can perform detection at a low sensitivity and in a wide concentration range, and can quantify the concentration of a target protein on the basis thereof, and thus can be used for effectively measuring autophagy markers. Therefore, the nanoplasmonic biosensor according to the present invention can be variously used for: the detection of a complex mixture; the early detection of cancer; the early prevention of infections, neurological disorders and the like; and the like.

Abstract: The lighting device disclosed in the embodiment of the invention includes a light emitting device package including a plurality of lead frames, a body coupled to the plurality of lead frames, a cavity in which a front side portion of the body is opened, and a light emitting chip disposed on a first lead frame that is any one of the plurality of lead frames; a circuit board on which the light emitting device package is disposed and having a first pad portion; a resin layer covering the light emitting device package on the circuit board; a reflective member disposed between the resin layer and the circuit board and into which a lower portion of the light emitting device package is inserted; and a light blocking portion overlapping the light emitting device package in a vertical direction on the resin layer, wherein the first lead frame may include a first frame disposed at a bottom of the cavity and is bent from the first frame to a lower surface of the body, and a first bonding portion coupled to the first pad

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; light sources disposed on the substrate; and a resin layer disposed on the substrate and the light sources. a first reflective layer disposed on the resin layer, wherein the resin layer includes an exit surface facing the light sources, and the exit surface of the resin layer includes convex portions facing each of the light sources and recess portions respectively disposed between the plurality of convex portions, concave surfaces disposed in each of the plurality of recess portions may have a curvature, and a radius of curvature of the concave surfaces may increase in one direction.

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; a light source including a plurality of light emitting devices disposed on the substrate; a resin layer disposed on the substrate; and a first diffusion layer disposed on the resin layer, wherein the resin layer includes a first resin portion disposed on the light source, and a second resin portion adjacent to the first resin portion and disposed on the substrate. The upper surface of the first resin portion has an inclination and is spaced apart from the first diffusion layer, the second resin portion includes a material different from that of the first resin portion, and the second resin portion based on the upper surface of the substrate. The height of the upper surface may be greater than the lowermost height of the upper surface of the first resin portion.

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; light sources disposed on the substrate; and a resin layer disposed on the substrate and the light sources. a first reflective layer disposed on the resin layer, wherein the resin layer includes an exit surface facing the light sources, and the exit surface of the resin layer includes convex portions facing each of the light sources and recess portions respectively disposed between the plurality of convex portions, concave surfaces disposed in each of the plurality of recess portions may have a curvature, and a radius of curvature of the concave surfaces may increase in one direction.

Abstract: The lighting device disclosed in the embodiment of the invention; a circuit board; a plurality of light emitting device packages disposed on the circuit board; a resin layer covering the plurality of light emitting device packages; and a layer for diffusing or reflecting light on the resin layer, wherein each light emitting device package includes a first side portion facing the circuit board, a second side portion opposite to the first side portion, third and fourth side portions on both sides of the first and second side portions, a cavity in which a part of a front side portion is opened; a plurality of lead frames each having a plurality of frames disposed on the bottom of the cavity and a bonding portion bent from each of the plurality of frames to a first side portion; and a plurality of light emitting chips electrically connected to the plurality of frames on the bottom of the cavity, and the cavity may have the same length as the length of the body in the first direction.

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; a light source including a plurality of light emitting devices disposed on the substrate; a resin layer disposed on the substrate; and a first diffusion layer disposed on the resin layer, wherein the resin layer includes a first resin portion disposed on the light source, and a second resin portion adjacent to the first resin portion and disposed on the substrate. The upper surface of the first resin portion has an inclination and is spaced apart from the first diffusion layer, the second resin portion includes a material different from that of the first resin portion, and the second resin portion based on the upper surface of the substrate. The height of the upper surface may be greater than the lowermost height of the upper surface of the first resin portion.

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; a plurality of light emitting devices on the substrate; a first reflective layer on the substrate; a resin layer on the first reflective layer and including a first surface from which light emitted from the light emitting device is extracted; a second reflective layer on the resin layer; and a light extraction layer on the first surface of the resin layer, wherein the first surface of the resin layer has a convex portion having a convex exit surface facing to each of the light emitting devices, and concave portions between the convex portions, and the light extraction layer may include a first extraction portion having protrusions on each exit surface, and second extraction portions concave between the plurality of protrusions.

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; a light source including a plurality of light emitting devices disposed on the substrate; a resin layer disposed on the substrate; and a first diffusion layer disposed on the resin layer, wherein the resin layer includes a first resin portion disposed on the light source, and a second resin portion adjacent to the first resin portion and disposed on the substrate. The upper surface of the first resin portion has an inclination and is spaced apart from the first diffusion layer, the second resin portion includes a material different from that of the first resin portion, and the second resin portion based on the upper surface of the substrate. The height of the upper surface may be greater than the lowermost height of the upper surface of the first resin portion.

Abstract: Disclosed are a nanoplasmonic biosensor for detecting an autophagy marker with high sensitivity using a plasmon resonance effect, and a method of detecting an autophagy marker and a method of screening a cancer therapeutic agent using the same.

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; light sources disposed on the substrate; and a resin layer disposed on the substrate and the light sources. a first reflective layer disposed on the resin layer, wherein the resin layer includes an exit surface facing the light sources, and the exit surface of the resin layer includes convex portions facing each of the light sources and recess portions respectively disposed between the plurality of convex portions, concave surfaces disposed in each of the plurality of recess portions may have a curvature, and a radius of curvature of the concave surfaces may increase in one direction.

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; a light source including a plurality of light emitting devices disposed on the substrate; a resin layer disposed on the substrate; and a first diffusion layer disposed on the resin layer, wherein the resin layer includes a first resin portion disposed on the light source, and a second resin portion adjacent to the first resin portion and disposed on the substrate. The upper surface of the first resin portion has an inclination and is spaced apart from the first diffusion layer, the second resin portion includes a material different from that of the first resin portion, and the second resin portion based on the upper surface of the substrate. The height of the upper surface may be greater than the lowermost height of the upper surface of the first resin portion.

Abstract: A lighting device disclosed in an embodiment of the invention includes a substrate; a reflective layer disposed on the substrate; a light source passing through the reflective layer and disposed on the substrate; a resin layer disposed on the reflective layer; and an optical pattern disposed on the resin layer, wherein the light source includes a first light emitting device and a second light emitting device spaced apart from the first light emitting device, wherein the optical pattern may include a first optical pattern disposed on an upper portion of the first light emitting device and a second optical pattern disposed on an upper portion of the second light emitting device, and the first optical pattern and the second optical pattern may have different areas.