Patents by Inventor Yu Deuerling-Zheng

Yu Deuerling-Zheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150282779
    Abstract: Systems and methods for treating an ischemic stroke are provided. In one aspect, a non-contrast scan is performed on a patient with a C-arm computed tomography (CT) imaging device in an interventional suite. A contrast agent is injected into the patient. A plurality of contrast scans is performed on the patient with the C-arm CT imaging device. Three-dimensional vascular images are reconstructed using the non-contrast scan and the plurality of contrast scans. A location of an ischemic stroke is determined from the reconstructed three-dimensional data sets and calculation of cerebral blood flow, mass transit time, time to peak, or a combination thereof. The ischemic stroke is treated in the interventional suite.
    Type: Application
    Filed: April 2, 2014
    Publication date: October 8, 2015
    Inventors: Yu Deuerling-Zheng, Klaus Klingenbeck
  • Publication number: 20150279084
    Abstract: In order to minimize streak artifacts within reconstructions of perfusion maps generated from moving C-arm acquisitions, a streak reduction method includes threshold analysis, time-contrast curve analysis, and total variation analysis. One or more mask volumes and a plurality of contrast agent enhanced volumes are generated based on a plurality of projections generated using a moving C-arm X-ray device. A maximum contrast attenuation volume is generated based on the plurality of contrast agent enhanced volumes. Voxels are identified as streaks based on analyses applied to the one or more mask volumes, the plurality of contrast agent enhanced volumes, and the maximum contrast attenuation volume, respectively.
    Type: Application
    Filed: April 25, 2014
    Publication date: October 1, 2015
    Inventors: Yu Deuerling-Zheng, Michael Manhart
  • Patent number: 8755583
    Abstract: A method and apparatus for generating at least one functional data set of a perfused region of the human or animal body are proposed. A first image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a first artery supplying the region. A second image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a second artery supplying the region. A first functional data set is generated by pixel-based calculation of at least one perfusion parameter from the first image data set. A second functional data set is generated by pixel-based calculation of at least one perfusion parameter from the second image data set.
    Type: Grant
    Filed: March 23, 2010
    Date of Patent: June 17, 2014
    Assignee: Siemens Aktiengesellschaft
    Inventors: Yu Deuerling-Zheng, Thomas Redel, Michael Zellerhoff
  • Patent number: 8738115
    Abstract: In a method and system for planning and implementing a selective internal radiation therapy (SIRT), the liver volume and the tumor volume are automatically calculated in a processor by analysis of items segmented from images obtained from the patient using one or more imaging modalities, with the administration of a contrast agent. The volume of therapeutic agent that is necessary to treat the tumor is automatically calculated from the liver volume, the tumor volume, and the body surface area of the patient and the lung shunt percentage for the patient. The therapeutic agent can be administered via respective feeder vessels in respectively different amounts that correspond to the percentage of blood supply to the tumor from the respective feeder vessels, this distribution also being automatically calculated by analysis of one or more parenchymal blood volume (PBV) images.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: May 27, 2014
    Assignee: Siemens Aktiengesellschaft
    Inventors: Jessica Amberg, Yu Deuerling-Zheng, Sigrid Ferschel, Stefan Lautenschlaeger, Oliver Meissner
  • Publication number: 20140126685
    Abstract: An angiographic examination method for examining an organ, vascular system or other regions of a patient is proposed. Projection images are acquired by an angiography system having an X-ray tube assembly and an X-ray image detector applied to ends of a C-arm, a patient table having a tabletop for carrying the patient, a system control unit, an imaging system and a monitor. Projection images are generated by rotational angiography from a plurality of projection angles. The projection images are subjected to a pre-processing of an FDK reconstruction, the result of which is filtered by a noise-reduction method. A predetermined number of dynamic, iterative reconstruction steps is carried out. Time attenuation curves are reconstructed, which are modeled with a weighted sum of linear basis functions.
    Type: Application
    Filed: August 30, 2013
    Publication date: May 8, 2014
    Inventors: Yu Deuerling-Zheng, Michael Manhart
  • Patent number: 8488861
    Abstract: A system and method of determining hemodynamic parameters of a patient is described. A background image data set is obtained prior to the administration of a contrast agent. A series of image data sets is obtained during the first passage of the bolus through a parenchymal volume. The pre-contrast-agent image is subtracted from image data sets obtained during the first passage of the contrast agent bolus, so that the amount of contrast agent in the volume may be determined. The time series of the amount of contrast agent is computed to determine the arterial input function (AIF) which may be used to determine a tissue impulse response, and hemodynamic parameters such as cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT).
    Type: Grant
    Filed: October 3, 2008
    Date of Patent: July 16, 2013
    Assignee: Siemens Aktiengesellschaft
    Inventors: Yu Deuerling-Zheng, Jan Boese, Michael Zellerhoff
  • Publication number: 20130129172
    Abstract: A tomogram of a body is provided. Projection-image data obtained by a radiation-based projection method is used for providing the tomogram. Initial voxel data are first specified for a plurality of voxels of the body. Synthetic projection-image data are generated based upon a projection rule modeling a course of the projection method. Projection-error data is determined by comparing the synthetic projection-image data with the real projection-image data. The projection-error data are imaged on the basis of a back-projection rule dependent on the projection rule so that voxel-error data are produced. Correction data is generated from the voxel-error data by a gradient-based optimizing algorithm, wherein corrected voxel data are generated using the correction data.
    Type: Application
    Filed: November 19, 2012
    Publication date: May 23, 2013
    Inventors: Jan Boese, Yu Deuerling-Zheng, Sabine Heiland, Martin Wagner
  • Publication number: 20110282193
    Abstract: In a method and system for planning and implementing a selective internal radiation therapy (SIRT), the liver volume and the tumor volume are automatically calculated in a processor by analysis of items segmented from images obtained from the patient using one or more imaging modalities, with the administration of contrast agent. In the processor, the volume of therapeutic agent that is necessary to treat the tumor is automatically calculated from the liver volume, the tumor volume, and the body surface area of the patient and the lung shunt percentage for the patient. The segmented tumor, as well as segmented feeder vessels are overlaid on a live fluoroscopic image of the patient during SIRT, to assist in positioning a catheter for administering the therapeutic agent, which is then administered according to the calculated volume.
    Type: Application
    Filed: May 11, 2010
    Publication date: November 17, 2011
    Inventors: Jessica Amberg, Yu Deuerling-Zheng, Sigrid Ferschel, Stefan Lautenschlaeger, Oliver Meissner
  • Patent number: 8054941
    Abstract: The invention relates to a method for the production of angiography recordings. First, a mask image is recorded with a first modality. A contrast medium is injected after the first recording. A control image is recorded with a second modality after the injection of the contrast medium. A spreading of the contrast medium is determined based on the images and the control of subsequent recordings is analyzed. A recording criterion is checked to determine whether the recording criterion has been achieved. If it has not been achieved, the control image is repeatedly recorded for repeatedly determining the spreading of the contrast medium. If it has been achieved, a contrast image is recorded with the first modality and the mask image and the contrast image are processed and analyzed.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: November 8, 2011
    Assignee: Siemens Aktiengesellschaft
    Inventors: Jan Boese, Yu Deuerling-Zheng, Michael Zellerhoff
  • Patent number: 8023707
    Abstract: The invention relates to an evaluation method for mapping the myocardium of a patient, in particular the automated, functional evaluation, for instance the heart perfusion, in angiographic series with the steps: recording a series of angiographic recordings directly after administering a contrast agent to the patient; determining a reference area in an angiographic recording; determining a trend pattern of the contrast agent as a reference curve within the reference area from the series of angiographic recordings; obtaining trend patterns of the contrast agent from all areas of the angiographic recordings; determining the correlation between the trend patterns and the reference curve as a measure for the interrelationship between statistical variables, comparison with stored reference curve; comparison of the correlation coefficient with a threshold value; and reproduction of a marker identifying the myocardium.
    Type: Grant
    Filed: March 25, 2008
    Date of Patent: September 20, 2011
    Assignee: Siemens Aktiengesellschaft
    Inventors: Jan Boese, Yu Deuerling-Zheng
  • Patent number: 8023732
    Abstract: A method is provided for accelerating non-rigid image registration, using parallel processors. To that end, on a commercially available graphics card, a block-matching algorithm is implemented, which, by histogram-based similarity standards, calculates the motion vectors for individual blocks. All the blocks are processed simultaneously and individually. The complete motion vector field is obtained by bilinear interpolation. Optimized search methods, such as conjugate direction searching, are employed. The algorithm terminates once the optimal displacement has been found for all the blocks. The registration is done completely on the graphics card. The algorithm is fully automatic, precise, and fast. The program may be employed for instance in registration for digital subtraction angiography.
    Type: Grant
    Filed: July 20, 2007
    Date of Patent: September 20, 2011
    Assignee: Siemens Aktiengesellschaft
    Inventors: Yu Deuerling-Zheng, Christian Eisenacher, Adam K. Galant, Joachim Hornegger, Marc Stamminger
  • Publication number: 20100246916
    Abstract: A method and apparatus for generating at least one functional data set of a perfused region of the human or animal body are proposed. A first image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a first artery supplying the region. A second image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a second artery supplying the region. A first functional data set is generated by pixel-based calculation of at least one perfusion parameter from the first image data set. A second functional data set is generated by pixel-based calculation of at least one perfusion parameter from the second image data set.
    Type: Application
    Filed: March 23, 2010
    Publication date: September 30, 2010
    Inventors: Yu Deuerling-Zheng, Thomas Redel, Michael Zellerhoff
  • Publication number: 20100027751
    Abstract: The invention relates to a method for the production of angiography recordings. First, a mask image is recorded with a first modality. A contrast medium is injected after the first recording. A control image is recorded with a second modality after the injection of the contrast medium. A spreading of the contrast medium is determined based on the images and the control of subsequent recordings is analyzed. A recording criterion is checked to determine whether the recording criterion has been achieved. If it has not been achieved, the control image is repeatedly recorded for repeatedly determining the spreading of the contrast medium. If it has been achieved, a contrast image is recorded with the first modality and the mask image and the contrast image are processed and analyzed.
    Type: Application
    Filed: July 23, 2009
    Publication date: February 4, 2010
    Inventors: Jan Boese, Yu Deuerling-Zheng, Michael Zellerhoff
  • Publication number: 20090092308
    Abstract: A system and method of determining hemodynamic parameters of a patient is described. A background image data set is obtained prior to the administration of a contrast agent. A series of image data sets is obtained during the first passage of the bolus through a parenchymal volume. The pre-contrast-agent image is subtracted from image data sets obtained during the first passage of the contrast agent bolus, so that the amount of contrast agent in the volume may be determined. The time series of the amount of contrast agent is computed to determine the arterial input function (AIF) which may be used to determine a tissue impulse response, and hemodynamic parameters such as cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT).
    Type: Application
    Filed: October 3, 2008
    Publication date: April 9, 2009
    Inventors: Yu Deuerling-Zheng, Jan Boese, Michael Zellerhoff
  • Publication number: 20080240338
    Abstract: The invention relates to an evaluation method for mapping the myocardium of a patient, in particular the automated, functional evaluation, for instance the heart perfusion, in angiographic series with the steps: recording a series of angiographic recordings directly after administering a contrast agent to the patient; determining a reference area in an angiographic recording; determining a trend pattern of the contrast agent as a reference curve within the reference area from the series of angiographic recordings; obtaining trend patterns of the contrast agent from all areas of the angiographic recordings; determining the correlation between the trend patterns and the reference curve as a measure for the interrelationship between statistical variables, comparison with stored reference curve; comparison of the correlation coefficient with a threshold value; and reproduction of a marker identifying the myocardium.
    Type: Application
    Filed: March 25, 2008
    Publication date: October 2, 2008
    Inventors: Jan Boese, Yu Deuerling-Zheng
  • Publication number: 20080037845
    Abstract: A method is provided for accelerating non-rigid image registration, using parallel processors. To that end, on a commercially available graphics card, a block-matching algorithm is implemented, which, by histogram-based similarity standards, calculates the motion vectors for individual blocks. All the blocks are processed simultaneously and individually. The complete motion vector field is obtained by bilinear interpolation. Optimized search methods, such as conjugate direction searching, are employed. The algorithm terminates once the optimal displacement has been found for all the blocks. The registration is done completely on the graphics card. The algorithm is fully automatic, precise, and fast. The program may be employed for instance in registration for digital subtraction angiography.
    Type: Application
    Filed: July 20, 2007
    Publication date: February 14, 2008
    Inventors: YU DEUERLING-ZHENG, Christian Eisenacher, Adam Galant, Joachim Hornegger, Marc Stamminger