Patents by Inventor Yuanfang MA

Yuanfang MA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10918739
    Abstract: The present disclosure discloses a human sDR5-Fc fusion protein in the preparation of adjuvant therapy for myocardial ischemia-reperfusion injury. The sDR5-Fc antibody fusion protein of the disclosure is prepared by connecting the 182 amino acids in DR5 extracellular domain with the human anti-Fc fragments. It has been tested that the sDR5-Fc antibody fusion protein of the disclosure can basically avoid Fc-mediated ADCC effect and can significantly reduce the area of myocardial infarction in rats of myocardial ischemia-reperfusion models.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: February 16, 2021
    Assignee: Suzhou Yongxin Biological Science and Technology Co., Ltd
    Inventor: Yuanfang Ma
  • Publication number: 20180161450
    Abstract: The present disclosure discloses a human sDR5-Fc fusion protein in the preparation of adjuvant therapy for myocardial ischemia-reperfusion injury. The sDR5-Fc antibody fusion protein of the disclosure is prepared by connecting the 182 amino acids in DR5 extracellular domain with the human anti-Fc fragments. It has been tested that the sDR5-Fc antibody fusion protein of the disclosure can basically avoid Fc-mediated ADCC effect and can significantly reduce the area of myocardial infarction in rats of myocardial ischemia-reperfusion models. The disclosure has great potential for development as a candidate drug for the preparation of new drugs for the treatment of myocardial ischemia-reperfusion injury.
    Type: Application
    Filed: May 10, 2016
    Publication date: June 14, 2018
    Inventor: Yuanfang MA