Patents by Inventor Yuhpyng Chen

Yuhpyng Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070270426
    Abstract: The present invention relates to compounds of the Formula wherein R3, R5, R7, U, X, Y and Z are as defined. Compounds of the Formula I have activity inhibiting production of A?-peptide. This invention also relates to pharmaceutical compositions and methods of treating diseases, for example, neurodegenerative diseases, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
    Type: Application
    Filed: July 17, 2007
    Publication date: November 22, 2007
    Inventor: YUHPYNG CHEN
  • Publication number: 20070270474
    Abstract: The invention provides compounds of Formula I: wherein R1, R2, R3, R4, R6, R7, R8 and A are as defined. Compounds of formula I have activity inhibiting production of A?-peptide. The invention also provides pharmaceutical compositions and methods for treating diseases, for example Alzheimer's disease, in mammals comprising compounds of Formula I.
    Type: Application
    Filed: July 2, 2007
    Publication date: November 22, 2007
    Inventors: Yuhpyng Chen, Spiros Liras, Robert Rosati, Martin Allen
  • Publication number: 20070265327
    Abstract: The present invention relates to compounds of the Formula wherein R1, R3, R4, R5, R6, R7 and R8 are as defined. Compounds of the Formula I have activity inhibiting production of A?-peptide. The invention also relates to pharmaceutical compositions and methods of treating disorders and diseases, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
    Type: Application
    Filed: July 5, 2007
    Publication date: November 15, 2007
    Inventors: Yuhpyng Chen, Lei Zhang
  • Publication number: 20070066613
    Abstract: The present invention relates to compounds of Formula I wherein R1, R2, R3, R4, R6, R7 and A are as defined. Compounds of Formula I have activity inhibiting production of A?-peptide. The invention also relates to pharmaceutical compositions and methods for treating diseases and disorders, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of Formula I.
    Type: Application
    Filed: September 20, 2006
    Publication date: March 22, 2007
    Inventors: Michael Brodney, Karen Coffman, Edward Kleinman, Brian O'Neill, Yuhpyng Chen
  • Publication number: 20060084689
    Abstract: The present invention relates to compounds of the Formula I wherein R1, R3, R4, R5, R6 and R7 are as defined. Compounds of the Formula I have activity inhibiting production of A?-peptide. The invention also relates to pharmaceutical compositions and methods of treating disorders and diseases, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
    Type: Application
    Filed: March 11, 2005
    Publication date: April 20, 2006
    Inventor: Yuhpyng Chen
  • Publication number: 20050222219
    Abstract: The present invention relates to compounds of the Formula I wherein R1, R3, R5, R7, X, Y and U are as defined. Compounds of the Formula I have activity inhibiting production of A?-peptide. The invention also relates to pharmaceutical compositions and methods of treating diseases and disorders, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
    Type: Application
    Filed: March 11, 2005
    Publication date: October 6, 2005
    Inventor: Yuhpyng Chen
  • Publication number: 20050222239
    Abstract: The present invention relates to compounds of the Formula wherein R1, R3, R4, R5, R6, R7 and R8 are as defined. Compounds of the Formula I have activity inhibiting production of A?-peptide. The invention also relates to pharmaceutical compositions and methods of treating disorders and diseases, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
    Type: Application
    Filed: March 11, 2005
    Publication date: October 6, 2005
    Inventors: Yuhpyng Chen, Lei Zhang
  • Publication number: 20050222227
    Abstract: The present invention relates to compounds of the Formula I wherein R1, R3, R5, R6 and R7 are as defined. Compounds of the Formula I have activity inhibiting production of A?-peptide. The invention also relates to pharmaceutical compositions and methods of treating diseases and disorders, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
    Type: Application
    Filed: March 11, 2005
    Publication date: October 6, 2005
    Inventor: Yuhpyng Chen
  • Publication number: 20050222149
    Abstract: The present invention relates to compounds of the Formula I wherein R1, R3, R5, R6, R7, X and Y are as defined. Compounds of the Formula I have activity inhibiting production of A?-peptide. The invention also relates to pharmaceutical compositions and methods of treating diseases and disorders, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
    Type: Application
    Filed: March 11, 2005
    Publication date: October 6, 2005
    Inventors: Yuhpyng Chen, Lei Zhang
  • Publication number: 20050171095
    Abstract: The present invention relates to a pharmaceutical composition for treating, for example, a disorder or condition selected from the group consisting of hypertension, depression, generalized anxiety disorder, phobias, posttraumatic stress disorder, avoidant personality disorder, sexual dysfunction, eating disorders, obesity, chemical dependencies, cluster headache, migraine, pain, Alzheimer's disease, obsessive-compulsive disorder, panic disorder, memory disorders, Parkinson's diseases, endocrine disorders, cerebellar ataxia, gastrointestinal tract disorders, negative symptoms of schizophrenia, premenstrual syndrome, Fibromyalgia Syndrome, stress incontinence, Tourette syndrome, trichotillomania, kleptomania, male impotence, cancer, chronic paroxysmal hemicrania and headache in a mammal, preferably a human, comprising (i) a corticotropin releasing factor antagonist or a pharmaceutically acceptable salt thereof, (ii) a 5-HT1B receptor antagonist or a pharmaceutically acceptable salt thereof, wherein the 5-HT1
    Type: Application
    Filed: December 31, 2004
    Publication date: August 4, 2005
    Inventors: Harry Howard, Yuhpyng Chen
  • Publication number: 20050107381
    Abstract: The present invention relates to compounds of the Formula wherein R1, R1a, R1b, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, X, Y, W, U, Z, m and n are as defined. Compounds of the Formula I have activity inhibiting production of A?-peptide. This invention also relates to pharmaceutical compositions and methods of treating diseases, for example, neurodegenerative diseases, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
    Type: Application
    Filed: August 2, 2004
    Publication date: May 19, 2005
    Inventor: Yuhpyng Chen
  • Publication number: 20050043372
    Abstract: The present invention relates to compounds of the Formula wherein R3, R5, R7, U, X, Y and Z are as defined. Compounds of the Formula I have activity inhibiting production of A?-peptide. This invention also relates to pharmaceutical compositions and methods of treating diseases, for example, neurodegenerative diseases, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
    Type: Application
    Filed: August 20, 2004
    Publication date: February 24, 2005
    Applicants: Pfizer, Inc., Pfizer Products Inc.
    Inventor: Yuhpyng Chen
  • Publication number: 20050032859
    Abstract: The present invention relates to compounds of the Formula wherein R3, R5, R6, R7, and Z, and other variables enumerated under one or more of R3, R5, R6, R7, and Z, are as defined. Compounds of the Formula I have activity inhibiting production of A?-peptide. This invention also relates to pharmaceutical compositions and methods of treating diseases, for example, neurodegenerative diseases, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
    Type: Application
    Filed: August 5, 2004
    Publication date: February 10, 2005
    Applicants: Pfizer Inc., Pfizer Products, Inc.
    Inventor: Yuhpyng Chen
  • Publication number: 20050032846
    Abstract: A pharmaceutical composition for treatment of a disorder or condition the treatment of which can be effected or facilitated by antagonizing Corticotropin Releasing Factor (CRF). The pharmaceutical composition includes a pharmaceutically acceptable carrier and an effective amount to treat the disorder or condition of the following compound: or a pharmaceutically acceptable salt thereof, wherein A, B, Z, R3, R4, and R5 are as defined herein.
    Type: Application
    Filed: August 5, 2004
    Publication date: February 10, 2005
    Inventor: Yuhpyng Chen
  • Publication number: 20050009823
    Abstract: This invention relates to compounds of the formula wherein A, B, D, E, K, T, G, R3 and R5 are defined as in the specification, and to the pharmaceutically acceptable salts of such compounds.
    Type: Application
    Filed: January 22, 2004
    Publication date: January 13, 2005
    Inventor: Yuhpyng Chen
  • Patent number: 6525067
    Abstract: CRF antagonists of Formulas I-V, wherein the B group in the Formulas contains an oxime The variables in the Formulas have the meanings described herein.
    Type: Grant
    Filed: November 8, 2000
    Date of Patent: February 25, 2003
    Assignee: Pfizer Inc
    Inventor: Yuhpyng Chen