Patents by Inventor Yujia Dai

Yujia Dai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8299243
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: September 29, 2011
    Date of Patent: October 30, 2012
    Assignee: AbbVie Inc.
    Inventors: Yujia Dai, Steven K. Davidsen, Anna M. Ericsson, Kresna Hartandi, Zhiqin Ji, Michael R. Michaelides
  • Patent number: 8110572
    Abstract: Compounds that inhibit Aurora-kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.
    Type: Grant
    Filed: July 16, 2008
    Date of Patent: February 7, 2012
    Assignee: Abbott Laboratories
    Inventors: Yujia Dai, Zhiqin Ji, Michael R. Michaelides
  • Publication number: 20120022253
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: September 29, 2011
    Publication date: January 26, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Yujia Dai, Steven K. Davidsen, Anna M. Ericsson, Kresna Hartandi, Zhiqin Ji, Michael R. Michaelides
  • Patent number: 8063091
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: July 22, 2009
    Date of Patent: November 22, 2011
    Assignee: Abbott Laboratories
    Inventors: Yujia Dai, Steven K. Davidsen, Anna M. Ericsson, Kresna Hartandi, Zhiqin Ji, Michael R. Michaelides
  • Publication number: 20100298323
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
    Type: Application
    Filed: June 3, 2010
    Publication date: November 25, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Milan Bruncko, Yujia Dai, Hong Ding, George A. Doherty, Steven W. Elmore, Lisa Hasvold, Laura Hexamer, Aaron R. Kunzer, Robert A. Mantei, William J. McClellan, Chang H. Park, Cheol-Min Park, Andrew M. Petros, Xiaohong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao, Gary T. Wang, Le Wang, Xilu Wang, Michael D. Wendt, Todd M. Hansen
  • Patent number: 7812166
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: October 28, 2005
    Date of Patent: October 12, 2010
    Assignee: Abbott Laboratories
    Inventors: Yujia Dai, Kresna Hartandi, Michael R. Michaelides
  • Publication number: 20100160322
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
    Type: Application
    Filed: December 4, 2009
    Publication date: June 24, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Milan Bruncko, Yujia Dai, Hong Ding, George A. Doherty, Steven W. Elmore, Lisa Hasvold, Laura Hexamer, Aaron Kunzer, Robert A. Mantei, William J. McClellan, Chang H. Park, Cheol-Min Park, Andrew M. Petros, Xiaohong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao, Gary T. Wang, Le Wang, Xilu Wang, Michael D. Wendt
  • Publication number: 20090286784
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: July 22, 2009
    Publication date: November 19, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Yujia Dai, Steven K. Davidsen, Anna M. Ericsson, Kresna Hartandi, Zhiqin Ji, Michael R. Michaelides
  • Patent number: 7598283
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: October 6, 2009
    Assignee: Abbott Laboratories, Inc.
    Inventors: Yujia Dai, Steven K. Davidsen, Anna M. Ericsson, Kresna Hartandi, Zhiqin Ji, Michael R. Michaelides
  • Patent number: 7560552
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: March 20, 2003
    Date of Patent: July 14, 2009
    Assignee: Abbott Laboratories
    Inventors: Michael R. Michaelides, Lee D. Arnold, Michael L. Curtin, Yujia Dai, Steven K. Davidsen, Robin R. Frey, Yan Guo, Zhiqin Ji, Neil Wishart
  • Publication number: 20090054430
    Abstract: Compounds that inhibit Aurora-kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.
    Type: Application
    Filed: July 16, 2008
    Publication date: February 26, 2009
    Applicant: Abbott Laboratories
    Inventors: Yujia Dai, Ji Zhiqin, Michael R. Michaelides
  • Publication number: 20080076767
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: October 5, 2007
    Publication date: March 27, 2008
    Inventors: Yujia Dai, Steven Davidsen, Anna Ericsson, Kresna Hartandi, Zhiqin Ji, Michael Michaelides
  • Patent number: 7297709
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: November 20, 2007
    Assignee: Abbott Laboratories
    Inventors: Yujia Dai, Steven K. Davidsen, Anna M. Ericsson, Kresna Hartandi, Zhiqin Ji, Michael R. Michaelides
  • Publication number: 20070135387
    Abstract: Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.
    Type: Application
    Filed: December 8, 2006
    Publication date: June 14, 2007
    Inventors: Michael Michaelides, William McClellan, Robin Frey, Michael Curtin, Douglas Steinman, Yujia Dai, James Holms
  • Publication number: 20060276490
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: August 16, 2006
    Publication date: December 7, 2006
    Inventors: Michael Michaelides, Lee Arnold, Michael Curtin, Yujia Dai, Steven Davidsen, Robin Frey, Yan Guo, Zhiqin Ji, Neil Wishart
  • Publication number: 20060178378
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: October 28, 2005
    Publication date: August 10, 2006
    Inventors: Yujia Dai, Kresna Hartandi, Michael Michaelides
  • Publication number: 20050020603
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: May 10, 2004
    Publication date: January 27, 2005
    Inventors: Yujia Dai, Steven Davidsen, Anna Ericsson, Kresna Hartandi, Zhiqin Ji, Michael Michaelides
  • Publication number: 20040235892
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: May 22, 2003
    Publication date: November 25, 2004
    Inventors: Yujia Dai, Steven K. Davidsen, Anna M. Ericsson, Kresna Hartandi, Zhiqin Ji, Michael R. Michaelides
  • Publication number: 20040014756
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: March 20, 2003
    Publication date: January 22, 2004
    Inventors: Michael R. Michaelides, Michael L. Curtin, Yujia Dai, Steven K. Davidsen, Robin R. Frey, Yan Guo, Zhiqin Ji
  • Publication number: 20030225273
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: March 3, 2003
    Publication date: December 4, 2003
    Inventors: Michael R. Michaelides, Michael L. Curtin, Yujia Dai, Steven K. Davidsen, Robin R. Frey, Yan Guo, Zhiqin Ji