Abstract: An object of the present invention is to provide a therapeutic agent for fatty liver diseases. The above object can be achieved by a therapeutic agent for a fatty liver disease, comprising a compound represented by the following formula (1): or a pharmaceutically acceptable salt thereof.

Abstract: Provided is a compound having ?4 integrin inhibitory action. The compound is a sulfonamide derivative represented by the following formula (I), or pharmaceutically acceptable salt thereof: where R1 to R5, e to h, D, and B represent those as described in the specification.

Abstract: Provided is a compound having ?4 integrin inhibitory action. The compound is a sulfonamide derivative represented by the following formula (I), or pharmaceutically acceptable salt thereof: where R1 to R5, e to h, D, and B represent those as described in the specification.

Abstract: A paint film-protecting sheet, which is unwound from a roll for use, and in which occurrence of adhesive transfer at edges thereof is effectively prevented, and a method of manufacturing same are provided. The paint film-protecting sheet is in the form of a roll obtained by winding in a lengthwise direction a pressure-sensitive adhesive sheet formed of a substrate in continuous sheet form and a pressure-sensitive adhesive layer disposed on the substrate. The substrate comprises a resin component made primarily of polyethylene resin or polypropylene resin. The paint film-protecting sheet, after being unwound from the roll, has a percent shrinkage, in the lengthwise direction, of not greater than 1.2% when heated at 80° C. for 1 hour.

Abstract: A paint film-protecting sheet (1) that effectively prevents adhesive transfer to the paint film is provided. The paint film-protecting sheet (1) includes a pressure-sensitive adhesive (PSA) layer (20), which is comprised of a non-crosslinking PSA, disposed on a polyolefin-based resin film serving as a supporting substrate (10). At least a surface portion (12) of the supporting substrate which adjoins the PSA layer is formed of a resin material that satisfies both of the following conditions: (1) it contains W wt % of a LLDPE having a density d of 0.925 g/cm3 or less, wherein W is greater than or equal to 20; and (2) it has a LLDPE content index ? of 400 or more, the LLDPE content index ? being defined as (0.935?d)×W×1000.

Abstract: A paint film-protecting sheet (1) is provided which effectively prevents adhesive transfer to the paint film. The paint film-protecting sheet (1) has a pressure-sensitive adhesive layer which is comprised of a non-crosslinking pressure-sensitive adhesive (20) adjacent a polyolefin-based resin film serving as a supporting substrate (10). At least a surface portion (12) of the supporting substrate that adjoins the pressure-sensitive adhesive layer satisfies the following conditions: (1) it has an indentation modulus at 25° C. (Er(25)) of from 200 MPa to 1,100 MPa and (2) it has an indentation modulus at ?5° C. (Er(?5)) of from 400 MPa to 2,400 MPa.

Abstract: Provided is a protective sheet for glasses, which has excellent workability, visibility and transparency. A protective sheet for glasses, characterized by having a distinctness of image of 70% or more and an internal haze of 3.0% or less as measured in accordance with JIS K7136.

Abstract: Provided is a protective sheet for glasses, which has excellent workability, adhesion reliability, visibility and impact resistance. A protective sheet for glasses, characterized by having a scratched area ratio of 0.15% or less as measured in an impact resistance test, a tensile elastic modulus of 50 MPa to 3500 MPa as measured in accordance with JIS K7124, a bending strength of 2.0×107 to 5.5×1010 ?m3·MPa, a distinctness of image of 70% or more, and a thickness of 45 to 250 ?m.

Abstract: Compounds represented by formula (1) and pharmaceutically acceptable salt thereofs: wherein each symbol is as defined in the specification, are useful as inhibitors of an activated blood coagulation factor X. Compositions which contain, as an active ingredient, an FXa selective low-molecular weight FXa inhibitor having a short serum half-life are particularly useful as anticoagulants for an extracorporeal blood circuit.

Abstract: Disclosed is a protective film for an automotive wheel, including a base layer and a pressure-sensitive adhesive layer, wherein a trouser tear strength in the machine direction (MID) of the protective film is 3 N or more, and an adhesive force (adherend: a panel with an acrylic clear coating, after standing for 48 hours under the conditions of 23° C. and 50% RH) of the protective film is 4.9 N/25 mm or more at a peeling speed of 0.3 m/minute, and is 19.6 N/25 mm or less at a peeling speed of 30 m/minute.

Abstract: Provided is a protective film for an automotive wheel having excellent performances, which has excellent weatherability and can sufficiently prevent a decrease in an adhesive force and the like. The protective film for an automotive wheel is a protective film for an automotive wheel, including a base layer and a pressure-sensitive adhesive layer, wherein the pressure-sensitive adhesive layer includes a pressure-sensitive adhesive composition containing at least a (meth)acryl-based polymer and a crosslinking agent, the (meth)acryl-based polymer contains a (meth)acryl-based monomer having an alkyl group of 1 to 14 carbon atoms as a main component, and contains, as other monomer components, at least a hydroxyl group-containing monomer as a constituent component, the content of the crosslinking agent is from 0.1 to 6 parts by weight based on 100 parts by weight of the acryl-based polymer, and the pressure-sensitive adhesive layer has a gel fraction of 60 to 95% by weight.

Abstract: Provided is a protective film for an automotive wheel having excellent performances, which can sufficiently prevent scratching of the wheel surface and staining, and also the generation of rust at a disc brake inside the wheel during a period until delivery of an automobile; and can be easily peeled. The protective film for an automotive wheel of the present invention is a protective film for an automotive wheel, including a base layer and a pressure-sensitive adhesive layer, wherein the pressure-sensitive adhesive layer of the protective film is bonded onto the back surface of the base layer of the protective film, and an adhesive force to the back surface after storage at 50° C. for 24 hours in an state of being bonded is from 0.1 to 2 N/20 mm at any peeling speed of 0.3 m/minute, 10 m/minute and 30 m/minute.

Abstract: A paint film-protecting sheet (1) is provided which effectively prevents adhesive transfer to the paint film. The paint film-protecting sheet (1) has a pressure-sensitive adhesive layer which is comprised of a non-crosslinking pressure-sensitive adhesive (20) adjacent a polyolefin-based resin film serving as a supporting substrate (10). At least a surface portion (12) of the supporting substrate that adjoins the pressure-sensitive adhesive layer satisfies the following conditions: (1) it has an indentation modulus at 25° C. (Er(25)) of from 200 MPa to 1,100 MPa and (2) it has an indentation modulus at ?5° C. (Er(?5)) of from 400 MPa to 2,400 MPa.

Abstract: A paint film-protecting sheet (1) that effectively prevents adhesive transfer to the paint film is provided. The paint film-protecting sheet (1) includes a pressure-sensitive adhesive (PSA) layer (20), which is comprised of a non-crosslinking PSA, disposed on a polyolefin-based resin film serving as a supporting substrate (10). At least a surface portion (12) of the supporting substrate which adjoins the PSA layer is formed of a resin material that satisfies both of the following conditions: (1) it contains W wt % of a LLDPE having a density d of 0.925 g/cm3 or less, wherein W is greater than or equal to 20; and (2) it has a LLDPE content index ? of 400 or more, the LLDPE content index ? being defined as (0.935?d)×W×1000.

Abstract: An edge-fastening tape (10) is provided that affixes an edge portion (20A) of a coating film protective sheet (20) to an adherend (30) having a coating film (32). The tape (10) has a rubber pressure-sensitive adhesive (PSA) layer (16) provided on one surface of a sheet-shaped support (12). An adhesive strength raising agent (14) that raises the adhesive strength of the PSA layer (16) with the passage of time is disposed between the PSA layer (16) and the support (12). The adhesive strength raising agent (14) is an acid-modified polyolefin resin that does not have a dominant endothermic peak corresponding to a softening temperature and/or a chlorinated polyolefin resin having a glass transition temperature below 10° C. in a DSC measurement.

Abstract: A paint film-protecting sheet, which is unwound from a roll for use, and in which occurrence of adhesive transfer at edges thereof is effectively prevented, and a method of manufacturing same are provided. The paint film-protecting sheet is in the form of a roll obtained by winding in a lengthwise direction a pressure-sensitive adhesive sheet formed of a substrate in continuous sheet form and a pressure-sensitive adhesive layer disposed on the substrate. The substrate comprises a resin component made primarily of polyethylene resin or polypropylene resin. The paint film-protecting sheet, after being unwound from the roll, has a percent shrinkage, in the lengthwise direction, of not greater than 1.2% when heated at 80° C. for 1 hour.

Abstract: A paint film-protecting sheet that provides a high level of weather resistance and minimizes staining of the paint film, and a substrate for such a sheet are provided. The paint film-protecting sheet has a pressure-sensitive adhesive (PSA) layer formed on a sheet-like substrate. The substrate has a surface resin layer (layer A) forming a surface of the substrate on the PSA layer side and one, two or more resin layers (layers B) superimposed on a back side of the layer A. The layer B contains an organic weathering stabilizer HMS having a weight-average molecular weight Mw of at least 1.5×103 in a predetermined amount Pb. The layer A is either free of the organic weathering stabilizer HMS or contains the stabilizer in a predetermined amount Pa which satisfies the condition Pa/Pb?0.5.

Abstract: Compounds represented by formula (1) and pharmaceutically acceptable salt thereofs: wherein each symbol is as defined in the specification, are useful as inhibitors of an activated blood coagulation factor X. Compositions which contain, as an active ingredient, an FXa selective low-molecular weight FXa inhibitor having a short serum half-life are particularly useful as anticoagulants for an extracorporeal blood circuit.

Abstract: Disclosed is an adhesive sheet for protecting a glass, which is excellent in weather resistance, adhesion reliability, transparency and impact resistance. Also disclosed is a protective film for an automotive glass, which is prepared using the adhesive sheet. The adhesive sheet comprises an adhesive layer and a substrate, wherein the adhesive layer comprises an adhesive composition containing, as a base polymer, a (meth)acrylic polymer comprising the following components (A) to (C) as monomer units: (A) 40 to 99.9% by weight of 2-ethylhexyl(meth)acrylate; (B) 0.1 to 10% by weight of a (meth)acrylic monomer having a functional group; and (C) 0 to 59.9% by weight of a vinyl monomer which can be copolymerized with the component (A) and/or (B), and wherein the substrate has a trilaminar structure composed of a propylene layer, a polyethylene layer and a polypropylene layer.

Abstract: A ground pattern includes a plurality of integrally formed first to third ground lines. A plurality of first ground lines are arranged parallel to one another at equal intervals. A plurality of second ground lines are arranged parallel to one another at equal intervals between adjacent ones of the first ground lines. A plurality of third ground lines are arranged parallel to one another at equal intervals between adjacent ones of the first ground lines at a predetermined angle with respect to the second ground lines. The third ground lines each connect one end of one adjacent second ground line with the other end of another adjacent second ground line. The ground lines form triangular openings.