Abstract: Proposed is an injector in which when a solution containing biomolecules is injected into an injection target, a proportion of biomolecules that function in the injection target with respect to the injected biomolecules is large. This application also relates to a method of injecting a solution containing biomolecules into an injection target using the injector. In one aspect, the injector injects the solution containing biomolecules into the injection target from an injector main body without performing injection through a given structure in a state where the given structure is inserted into the injection target. The injector may include an accommodation unit and a nozzle unit, wherein the injector satisfies a given condition.

Abstract: A needleless injector configured to inject an injection intended substance to an injection target region, by injecting the injection intended substance includes a nozzle portion and a pressing portion, and a predetermined gap is formed between the nozzle portion and the pressing portion. The nozzle portion is formed to have a portion of the distal end portion that comes into contact with the injection target region and has a width (a) falling within a range from 3.5 mm to 5.5 mm, and a ratio (b/a) defined by an inner diameter (b) of a portion of a distal end portion of the pressing portion that comes into contact with the injection target region by the width (a) falls within a range from 1.5 to 5.0. A part of the injection target region is received in the predetermined gap when the pressing portion presses the injection target region.

Abstract: Proposed is a measurement system for measuring a behavior of an ejection liquid, which is ejected into an object from an ejection device, within the object. The system includes a container part formed of a resin material. The system also includes an imaging device disposed to image, across the object, a tip surface of the container part having an ejection port formed therein and being in contact with the object from a back side of the object in a predetermined state in which the ejection port is positioned from a front side of the object. The system further includes a first emission device that emits first near infrared light to the tip surface. In such a configuration, the behavior of the ejection liquid when the ejection liquid is ejected into the object from the ejection device can be imaged and measured by the imaging device.

Abstract: An object of the present disclosure is at least to provide a cell fusion method having a high cell fusion rate. The object is solved by a cell fusion method including pressurizing, by a pressurization portion, a solution containing multiple cells of one or more types and at least one type of chemical cell fusion agent, the solution contained in a container portion.

Abstract: This application relates to an injector in which when a solution containing biomolecules is injected into an injection target, a proportion of biomolecules that function in the injection target with respect to the injected biomolecules is large. This application also relates to a method of injecting a solution containing biomolecules into an injection target using the injector. In one aspect, the injector injects the solution containing biomolecules into the injection target from an injector main body without performing injection through a given structure in a state where the given structure is inserted into the injection target. The injector may include an accommodation unit and a nozzle unit, wherein the injector satisfies a given condition.

Abstract: An injector configured to inject a solution containing a biomolecule and a gas that is predetermined into an injection target without using an injection needle, the injector including a storage portion configured to store the solution containing the biomolecule and the gas, a nozzle portion communicating with the storage portion, the nozzle portion including an ejection port configured to eject the solution containing the biomolecule and the gas toward the injection target, and a pressurization portion configured to pressurize the solution containing the biomolecule and the gas that are stored in the storage portion during an operation and to eject the solution containing the biomolecule and the gas from the ejection port toward the injection target.

Abstract: This application relates to an ultra fine bubble production apparatus for producing ultra fine bubbles. The apparatus may include a container portion including a liquid and a gas, and a drive portion for pressurization in the container portion. In the pressurization, the time required for the pressure to reach the maximum pressure from the start of the pressurization can be 2.0 milliseconds or less, and the maximum pressure can be 4.00 MPa or more.

Abstract: An object of the present disclosure is at least to provide a device that can easily introduce a substance into cells in vitro with high efficiency and in a short time, and the object is fulfilled by a device for introducing a substance into cells in vitro, the device comprising: an accommodation unit for accommodating a solution containing cells and a substance; and a driving unit for pressurization of the solution, wherein regarding the pressurization of the solution, time from when the pressurization starts until pressure reaches a maximum pressure is 2.0 msec or shorter.

Abstract: This application relates to a measurement system for measuring a behavior of an ejection liquid, which is ejected into an object from an ejection device, within the object. The system includes a container part formed of a resin material. The system also includes an imaging device disposed to image, across the object, a tip surface of the container part having an ejection port formed therein and being in contact with the object from a back side of the object in a predetermined state in which the ejection port is positioned from a front side of the object. The system further includes a first emission device that emits first near infrared light to the tip surface. In such a configuration, the behavior of the ejection liquid when the ejection liquid is ejected into the object from the ejection device can be imaged and measured by the imaging device.

Abstract: A needleless injector configured to inject an injection intended substance to an injection target region, by injecting the injection intended substance includes a nozzle portion and a pressing portion, and a predetermined gap is formed between the nozzle portion and the pressing portion. The nozzle portion is formed to have a portion of the distal end portion that comes into contact with the injection target region and has a width (a) falling within a range from 3.5 mm to 5.5 mm, and a ratio (b/a) defined by an inner diameter (b) of a portion of a distal end portion of the pressing portion that comes into contact with the injection target region by the width (a) falls within a range from 1.5 to 5.0. A part of the injection target region is received in the predetermined gap when the pressing portion presses the injection target region.

Abstract: This application relates to an injector and a method that can directly inject a solution containing biomolecules into a cell nucleus of an injection target with high efficiency. In one aspect, the injector injects the solution containing biomolecules into the injection target from an injector main body without performing injection through a given structure in a state where the given structure is inserted into the injection target. The injector may include an accommodation unit for accommodating the solution containing biomolecules and a nozzle unit including an injection port through which the solution containing biomolecules flows and is injected into the injection target, the solution being pressurized. There may be a time at which an injection speed of the solution containing biomolecules is 40 m/s or more between an injection start time of the solution containing biomolecules and a time of 0.20 ms.

Abstract: This application relates to an injector in which when a solution containing biomolecules is injected into an injection target, a proportion of biomolecules that function in the injection target with respect to the injected biomolecules is large. This application also relates to a method of injecting a solution containing biomolecules into an injection target using the injector. In one aspect, the injector injects the solution containing biomolecules into the injection target from an injector main body without performing injection through a given structure in a state where the given structure is inserted into the injection target. The injector may include an accommodation unit and a nozzle unit, wherein the injector satisfies a given condition.

Abstract: This application relates to an injector that can directly inject a solution containing biomolecules into a cell nucleus of a wide range of injection targets with high efficiency. In one aspect, the injector injects a solution containing biomolecules into an injection target from an injector main body without performing injection through a given structure in a state where the given structure is inserted into the injection target. The injector may include an accommodation unit and a nozzle unit, wherein the injector satisfies given conditions.