Patents by Inventor Yuri Gleba

Yuri Gleba has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230406892
    Abstract: The present invention relates to bacteriocins for control of Salmonella enterica (salmocins). The bacteriocins are derived from Salmonella. The salmocins can be expressed in plants and can be used in a method of preventing or reducing infection or contamination of an object with Salmonella.
    Type: Application
    Filed: September 21, 2020
    Publication date: December 21, 2023
    Inventors: Simone Hahn, Tobias Schneider, Anett Stephan, Steve Schulz, Anatoli Giritch, Yuri Gleba, Heike Prochaska
  • Publication number: 20230270145
    Abstract: A product for oral consumption, such as a food, comprising at least one thaumatin selected from the group consisting of thaumatin I and thaumatin II and at least one sugar selected from the group consisting of sucrose, glucose, and fructose in a mass ratio of said thaumatin:to said sugar of from 1:2,000 to 1:80,000.
    Type: Application
    Filed: June 29, 2021
    Publication date: August 31, 2023
    Inventors: Anett Stephan, Simone Hahn-Löbmann, Heike Prochaska, Anatoli Giritch, Yuri Gleba
  • Publication number: 20220090107
    Abstract: The invention provides a plus-sense single-stranded RNA viral RNA molecule, comprising a segment encoding a movement protein, a segment encoding a coat protein and a segment that comprises a guide RNA (gRNA), wherein said RNA molecule can be translated, in infected cells, to a polyprotein comprising the movement protein and the coat protein.
    Type: Application
    Filed: May 22, 2020
    Publication date: March 24, 2022
    Inventors: Heike Prochaska, Stefano Torti, Anka Thümmler, Patrick Romer, Anatoli Gititch, Yuri Gleba
  • Publication number: 20220073575
    Abstract: The present invention relates to bacteriocins for control of Salmonella enterica (salmocins). The bacteriocins are derived from Salmonella. The salmocins can be expressed in plants and can be used in a method of preventing or reducing infection or contamination of an object with Salmonella.
    Type: Application
    Filed: September 21, 2021
    Publication date: March 10, 2022
    Inventors: Simone Hahn, Tobias Schneider, Anett Stephan, Steve Schulz, Anatoli Giritch, Yuri Gleba
  • Patent number: 11161886
    Abstract: The present invention relates to bacteriocins for control of Salmonella enterica (salmocins). The bacteriocins are derived from Salmonella. The salmocins can be expressed in plants and can be used in a method of preventing or reducing infection or contamination of an object with Salmonella.
    Type: Grant
    Filed: September 20, 2019
    Date of Patent: November 2, 2021
    Assignee: NOMAD BIOSCIENCE GMBH
    Inventors: Simone Hahn, Tobias Schneider, Anett Stephan, Steve Schulz, Anatoli Giritch, Yuri Gleba
  • Patent number: 10934553
    Abstract: A process of transiently transfecting a plant or leaves on a plant, comprising contacting said plant or said leaves with a suspension comprising Agrobacterium cells of strain CryX or a derivative strain of strain CryX, wherein said derivative strain has the chromosomal background of strain CryX or said derivative strain contains the vir plasmid of strain CryX or a derivative of said vir plasmid.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: March 2, 2021
    Assignee: Nomad Bioscience GmbH
    Inventors: Patrick Roemer, Luisa Bortesi, Doreen Tiede, Anatoli Giritch, Yuri Gleba
  • Publication number: 20200255847
    Abstract: The invention provides a method of producing a potexviral vector for expressing a protein of interest in a plant, comprising producing a second heterologous nucleic acid comprising a second ORF encoding said protein and having, in the second ORF, an increased GC-content compared to a first ORF encoding said protein in a first heterologous nucleic acid, and providing said potexviral vector comprising the following segments: (i) a nucleic acid sequence segment encoding a potexviral RNA-dependent RNA polymerase, (ii) a nucleic acid sequence comprising or encoding a potexviral triple-gene block, and (iii) said second heterologous nucleic acid or a portion thereof comprising said second ORF.
    Type: Application
    Filed: September 17, 2018
    Publication date: August 13, 2020
    Applicant: Nomad Bioscience GmbH
    Inventors: Stefano Torti, René Schlesier, Anatoli Giritch, Yuri Gleba
  • Publication number: 20200010517
    Abstract: The present invention relates to bacteriocins for control of Salmonella enterica (salmocins). The bacteriocins are derived from Salmonella. The salmocins can be expressed in plants and can be used in a method of preventing or reducing infection or contamination of an object with Salmonella.
    Type: Application
    Filed: September 20, 2019
    Publication date: January 9, 2020
    Inventors: Simone Hahn, Tobias Schneider, Anett Stephan, Steve Schulz, Anatoli Giritch, Yuri Gleba
  • Publication number: 20190338297
    Abstract: A process of transiently transfecting a plant or leaves on a plant, comprising contacting said plant or said leaves with a suspension comprising Agrobacterium cells of strain CryX or a derivative strain of strain CryX, wherein said derivative strain has the chromosomal background of strain CryX or said derivative strain contains the vir plasmid of strain CryX or a derivative of said vir plasmid.
    Type: Application
    Filed: July 23, 2019
    Publication date: November 7, 2019
    Inventors: Patrick Roemer, Luisa Bortesi, Doreen Tiede, Anatoli Giritch, Yuri Gleba
  • Patent number: 10435704
    Abstract: A process of producing a recombinant glycoprotein in a plant, in cells of a plant, or in plant cells is provided. The process comprises expressing in said plant, in cells of said plant or in said plant cells a nucleic acid sequence encoding a polypeptide having an N-glycosylation site and co-expressing a nucleic acid sequence encoding a heterologous single-subunit oligosaccharyltransferase.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: October 8, 2019
    Assignee: Icon Genetics GmbH
    Inventors: Franziska Jarczowski, Romy Kandzia, Frank Thieme, Victor Klimyuk, Yuri Gleba
  • Patent number: 10287602
    Abstract: A process of expressing a sequence of interest in a plant, plant part, or plant cell culture, comprising: (a) providing a plant, plant part, or plant cell culture containing in cell nuclei a heterologous DNA having a sequence encoding an RNA replicon operably linked or linkable to a transcription promoter, wherein said sequence encoding an RNA replicon contains (i) sequences for replicon function of said RNA replicon, said sequences being derived from a sequence of a plant RNA virus, (ii) a sequence of interest, whereby said sequences for replicon function exhibit at selected localities of said sequences of said plant RNA virus function-conservative differences from said sequence of said plant RNA virus, said differences causing an increased frequency of replicon formation compared to an RNA replicon not exhibiting said differences; and (b) causing expression of said sequence of interest.
    Type: Grant
    Filed: January 5, 2016
    Date of Patent: May 14, 2019
    Assignee: Icon Genetics GmbH
    Inventors: Sylvestre Marillonnet, Carola Engler, Victor Klimyuk, Yuri Gleba
  • Publication number: 20190136260
    Abstract: A process of transfecting a plant, comprising spraying parts of said plant with an aqueous suspension containing cells of an Agrobacterium strain and at least one abrasive suspended in said suspension, said Agrobacterium strain comprising a DNA molecule comprising a nucleic acid construct containing a DNA sequence of interest to be transfected into the plant.
    Type: Application
    Filed: November 19, 2018
    Publication date: May 9, 2019
    Inventors: Anatoli Giritch, Yuri Symonenko, Simone Hahn, Doreen Tiede, Anton Shvarts, Patrick Roemer, Yuri Gleba
  • Patent number: 10201168
    Abstract: The invention provides a method of preventing or reducing contamination of an object such as food with enterohaemorrhagic E. coli (EHEC), comprising contacting said object with colicin M or a derivative thereof.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: February 12, 2019
    Assignee: Nomad Bioscience GmbH
    Inventors: Anatoli Giritch, Simone Hahn, Steve Schulz, Anett Stephan, Yuri Gleba, Franziska Jarczowski
  • Patent number: 10052370
    Abstract: Protein conjugate comprising a protein antigen for generating an immune response against the HER2/neu protein and an immunogenic carrier covalently bonded to said protein antigen, wherein said protein antigen (i) has a sequence segment of 300 or more contiguous amino acids of the amino acid sequence of SEQ ID NO: 1; or (ii) has a variant sequence segment of 300 or more amino acid residues, wherein the amino acid sequence of said variant sequence segment has at least 85% sequence identity to a sequence portion from SEQ ID: 1; or (iii) has a variant sequence segment of 300 or more amino acid residues and has from 1 to 10 substitutions, deletions or additions in said variant sequence segment compared to a sequence segment of 300 or more amino acid residues of the amino acid sequence of SEQ ID NO: 1 or 2.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: August 21, 2018
    Assignees: ICON GENETICS GMBH, UNIVERSITY OF SOUTHAMPTON
    Inventors: Natalia Savelyeva, Franziska Jarczowski, Romy Kandzia, Anja Nickstadt, Frank Thieme, Victor Klimyuk, Yuri Gleba, Duc Bui-Minh, Freda K. Stevenson, Warayut Chotprakaikiat
  • Patent number: 9856484
    Abstract: A process of endowing a plant or plant cells with a trait of interest by expressing an RNA sequence of interest, said process comprising: providing plant cells or cells of said plant with a first vector and a second vector and selecting cells endowed with said trait of interest, wherein said first vector contains a first nucleotide sequence with a first segment coding, in 5? to 3? direction, for—a 5? part of said RNA sequence of interest and—a 5? part of an intron; and said second vector contains a second nucleotide sequence with a second segment coding, in 5? to 3? direction, for—a 3? part of an intron and—a 3? part of said RNA sequence of interest.
    Type: Grant
    Filed: January 30, 2004
    Date of Patent: January 2, 2018
    Assignee: BAYER CROPSCIENCE N.V.
    Inventors: Anatoly Giritch, Sylvestre Marillonnet, Victor Klimyuk, Yuri Gleba
  • Publication number: 20160345599
    Abstract: The invention provides a method of preventing or reducing contamination of an object such as food with enterohaemorrhagic E. coli (EHEC), comprising contacting said object with colicin M or a derivative thereof.
    Type: Application
    Filed: May 2, 2016
    Publication date: December 1, 2016
    Inventors: Anatoli Giritch, Simone Hahn, Steve Schulz, Anett Stephan, Yuri Gleba
  • Publication number: 20160208276
    Abstract: A process of expressing a sequence of interest in a plant, plant part, or plant cell culture, comprising: (a) providing a plant, plant part, or plant cell culture containing in cell nuclei a heterologous DNA having a sequence encoding an RNA replicon operably linked or linkable to a transcription promoter, wherein said sequence encoding an RNA replicon contains (i) sequences for replicon function of said RNA replicon, said sequences being derived from a sequence of a plant RNA virus, (ii) a sequence of interest, whereby said sequences for replicon function exhibit at selected localities of said sequences of said plant RNA virus function-conservative differences from said sequence of said plant RNA virus, said differences causing an increased frequency of replicon formation compared to an RNA replicon not exhibiting said differences; and (b) causing expression of said sequence of interest.
    Type: Application
    Filed: January 5, 2016
    Publication date: July 21, 2016
    Inventors: Sylvestre Marillonnet, Carola Engler, Victor Klimyuk, Yuri Gleba
  • Publication number: 20160145632
    Abstract: A process of producing transgenic plants or plant cells stably transformed on a chromosome with a DNA sequence of interest and capable of expressing a function of interest from said DNA sequence of interest, said process comprising (a) providing plant cells or plants with at least two different vectors, whereby (i) said at least two different vectors are adapted to recombine with each other by site-specific recombination in said plant cells for producing a non-replicating recombination product containing said DNA sequence of interest, (ii) said at least two different vectors are adapted for integrating said DNA sequence of interest into said chromosome, (iii) said DNA sequence of interest contains sequence portions from at least two of said at least two different vectors, said sequence portions being necessary for expressing said function of interest from said DNA sequence of interest; and (b) selecting plants or plant cells expressing said function of interest
    Type: Application
    Filed: November 24, 2015
    Publication date: May 26, 2016
    Inventors: Anatoly Giritch, Serik Eliby, Sylvestre Marillonnet, Victor Klimyuk, Yuri Gleba
  • Publication number: 20160115498
    Abstract: A process of producing a recombinant glycoprotein in a plant, in cells of a plant, or in plant cells, comprising expressing in said plant, in cells of said plant or in said plant cells a nucleic acid sequence encoding a polypeptide, said polypeptide having an N-glycosylation site of consensus sequence Asn-X-Ser or Asn-X-Thr, X being any standard amino acid residue, wherein, if the Asn residue of said N-glycosylation site is assigned amino acid sequence position 0, (a) the amino acid residue at position +3 is selected from Thr, Ser, Gly, Leu, Ile, Val and Met; or (b) the amino acid residue at position ?1 is selected from Glu and Asp.
    Type: Application
    Filed: June 3, 2014
    Publication date: April 28, 2016
    Inventors: Franziska Jarczowski, Romy Kandzia, Frank Thieme, Victor Klimyuk, Yuri Gleba
  • Publication number: 20160097056
    Abstract: Crop growth management system comprising a process of providing a plant with improved abiotic stress tolerance, comprising providing aerial parts of said plant with a suspension containing cells of an Agrobacterium strain comprising a nucleic acid molecule comprising a nucleic acid construct containing a nucleotide sequence of interest, said nucleotide sequence of interest providing said plant with increased abiotic stress tolerance upon expression in said plant.
    Type: Application
    Filed: May 23, 2014
    Publication date: April 7, 2016
    Inventors: Anka Tümmler, Doreen Bartels, Anatoli Giritch, Yuri Gleba