Abstract: The present disclosure provides antibody drug conjugates comprising STING modulators. Also provided are compositions comprising the antibody drug conjugates. The compounds and compositions are useful for stimulating an immune response in a subject in need thereof.

Abstract: The substrate processing apparatus includes a suction holding mechanism, a rotation mechanism, a plurality of lift pins, a vertical movement mechanism, and a horizontal movement mechanism. The suction holding mechanism sucks and holds a substrate. The rotation mechanism rotates the suction holding mechanism holding the substrate about the rotation axis. The vertical movement mechanism moves the plurality of lift pins in the vertical direction. A sensor measures the eccentric state of the substrate W held by the suction holding mechanism. The vertical movement mechanism supports the substrate from the suction holding mechanism by moving the plurality of lift pins and the horizontal movement mechanism moves the plurality of lift pins based on the eccentric state of the substrate measured by the sensor in a state where the substrate is supported.

Abstract: A holding mechanism holds a substrate horizontally. A rotation mechanism rotates the holding mechanism holding the substrate. A nozzle supplies a processing liquid to the substrate. A nozzle arm holds the nozzle. An arm actuation mechanism moves the nozzle arm between a processing position overlapping the substrate in plan view and a retracted position displaced from the substrate in plan view. A cup portion is disposed around the holding mechanism, and receives the processing liquid from the substrate. A cup actuation mechanism moves the cup portion up and down between an upper position and a lower position. A first container is fixed to the cup portion to be movable up and down integrally with the cup portion, and can accommodate the nozzle at the retracted position.

Abstract: According to one embodiment, a display device including a plurality of pixels each of which includes a memory is provided. The display device includes a plurality of signal lines connected to the plurality of pixels, a signal line drive circuit configured to provide a data signal to one of the memories through one of the signal lines, a readout circuit configured to read the data signal in the memory through the signal line, and an output wire configured to externally output the data signal read by the readout circuit without passing through the signal line drive circuit.

Abstract: An occupant state detection system includes first and second occupant monitoring apparatuses, a determination apparatus, and an occupant state detection apparatus. The first and second occupant monitoring apparatuses monitor a physical state of an occupant in a vehicle in different methods. The occupant state detection apparatus includes one or more first processors and one or more first memories. Upon receiving data indicating that the vehicle is in a stopped state from the determination apparatus, the one or more first processors cooperate with one or more programs in the one or more first memories to: make assignment of a part to be monitored and data to be acquired, of the occupant in the vehicle, to be detected by the first and second occupant monitoring apparatuses; and detect the physical state of the occupant on the basis of first and second occupant monitoring data from the first and second occupant monitoring apparatuses.

Abstract: A method for manufacturing a pillar-shaped honeycomb structure filter including; attaching ceramic particles to a surface of the first cells by ejecting an aerosol including the ceramic particles toward the inlet side end surface from a direction perpendicular to the inlet side end surface while applying a suction force to the outlet side end surface to suck the ejected aerosol from the inlet side end surface, wherein the ejection of the aerosol is carried out using an aerosol generator including a drive gas flow path for flowing a pressurized drive gas, a supply port provided on the way of the drive gas flow path and capable of sucking the ceramic particles from an outer peripheral side of the drive gas flow path toward an inside of the drive gas flow path, and a nozzle attached to a tip of the drive gas flow path and capable of ejecting the aerosol.

Abstract: An occupant state detection system includes an occupant monitoring apparatus, an occupant state detection apparatus, and a determination apparatus. The occupant state detection apparatus includes one or more processors and one or more memories. The one or more processors cooperate with one or more programs included in the one or more memories to receive occupant monitoring data from the occupant monitoring apparatus and determination data from the determination apparatus. On the basis of the determination data, the one or more processors make assignment of a part to be monitored, of an occupant in a vehicle, to be monitored by the occupant monitoring apparatus, to detect a physical state of the occupant.

Abstract: An occupant state detection system includes an occupant monitoring apparatus, a determination apparatus, and an occupant state detection apparatus. The occupant state detection apparatus includes one or more processors and one or more memories. The one or more memories store data including traveling-state comparative data and stopped-state comparative data. The one or more processors cooperate with one or more programs included in the one or more memories to receive occupant monitoring data from the occupant monitoring apparatus and determination data from the determination apparatus. On the basis of the determination data, the one or more processors compare the occupant monitoring data with the traveling-state comparative data on the condition that the vehicle is in the traveling state, and compare the occupant monitoring data with the stopped-state comparative data on the condition that the vehicle is in the stopped state, to detect a state of the occupant in the vehicle.

Abstract: A pillar-shaped honeycomb structure including a plurality of first cells extending from an inlet side end surface to an outlet side end surface, and a plurality of second cells extending from the inlet side end surface to the outlet side end surface, with a porous partition wall interposed therebetween, wherein a porous film having a porosity higher than that of the partition walls is provided on a surface of each of the first cells, and at a cross-section orthogonal to the direction in which the first cells of the pillar-shaped honeycomb structure filter extend, the average thickness of the porous film in the central portion is larger than the average thickness of the porous film in the outer peripheral portion.

Abstract: A support device of an embodiment includes a magnet unit, a first member, a second member, a magnetic member, and a magnetic fluid. The magnet unit generates a magnetic force. The first member is formed of a non-magnetic material and is disposed in a first direction of the magnet unit. The second member is formed of a non-magnetic material and is disposed in the first direction of the first member. The magnetic member is formed of a magnetic material and is disposed in the first direction of the second member. The magnetic fluid is disposed between the first member and the second member.

Abstract: An image reading device includes a light source configured to irradiate a subject; a reading unit configured to detect reflected light generated by a subject reflecting light emitted from the light source, to perform reading; and a control unit configured to perform turn-on control on the light source. The control unit is configured to perform the turn-on control to change a turn-on condition such that the light source is turned on during a period when at least a detection region including an image pattern on the subject passes through a reading position of a reading unit, based on position information of the image pattern of the subject in a first operation mode for reading the subject, and perform the turn-on control to make the turn-on condition of the light source constant regardless of the image pattern of the subject in a second operation mode for reading the subject.

Abstract: An inspection method for a pillar-shaped honeycomb filter having a honeycomb-shaped first end face and a honeycomb-shaped second end face, including: allowing gas containing fine particles to flow into the first end face; imaging the entire second end face covered with the sheet-like light using a camera while the gas that has flowed into the first end face flows out of the second end face through the filter, and generating an image of the entire second end face covered with the sheet-like light; selecting an inspection area of the second end face and measuring information concerning a sum of luminance of each pixel in the inspection area; and determining quality of the filter based on at least the information concerning the concentration of the fine particles in the gas before the gas flows into the first end face and the information concerning the sum of luminance.

Abstract: A method for producing a honeycomb structure for fine particle collection filters, the honeycomb structure including a plurality of porous honeycomb structure segments. The method includes joining each of the porous honeycomb segments via a joining material layers by applying a joining material between joining surfaces of each of the porous honeycomb structure segments, through a nozzle portion of a joining material applicator. The nozzle portion of the joining material applicator includes: a joining material introduction port; a joining material discharge space; and a joining material flow path having a bent portion, through which the joining material passes from the joining material introduction port to the joining material discharge space. The joining material flow path of the nozzle portion includes a buffer space configured such that a flow path cross section gradually expands toward the joining material discharge space on a downstream side of the bent portion.

Abstract: A honeycomb segment joined body includes a plurality of honeycomb segments; and joining layers for bonding side surfaces of the plurality of honeycomb segments. Each of the joining layers is a cured product of a pasty joining material, and has a standard deviation of joined widths of 0.30 or less. The honeycomb segment joined body is produced by applying pressurization with vibration when joining side surfaces of a plurality of honeycomb segments using a pasty joining material.

Abstract: A manufacturing method of a honeycomb structure includes a forming step of forming a quadrangular pillar-shaped honeycomb formed body, a firing step of firing the honeycomb formed body and forming a quadrangular pillar-shaped honeycomb fired body, a coating step of coating at least a part of side surfaces of the honeycomb fired body with a paste-like bonding material, a honeycomb block body preparing step of bonding the plurality of honeycomb fired bodies while performing pressurizing, to prepare a honeycomb block body, and a circumference grinding step of grinding a circumferential surface of the honeycomb block body and obtaining the honeycomb structure, and in the honeycomb block body preparing step, the bonding is performed without interposing any member other than the bonding material between the honeycomb fired bodies, and the bonding material has a shear thinning property.

Abstract: A lighting device (100) includes: a surface light source (1); a first lens (L1) having a first focal point (F1), the first lens being provided on the light exit surface side of the surface light source; and a second lens (L2) having a second focal point (F2), the second lens being provided on a light exit surface side of the first lens, the surface light source, the first lens, and the second lens being configured such that a first virtual image (I1) is formed by the first lens and a second virtual image (I2) is formed by the second lens, wherein the first virtual image (I1) is formed between the second focal point (F2) and the first lens, and the second focal point (F2) is on a side opposite to the light source side relative to a predetermined focal position f?.

Abstract: A manufacturing method of a honeycomb structure includes a forming step of forming a quadrangular pillar-shaped honeycomb formed body, a firing step of firing the honeycomb formed body and forming a quadrangular pillar-shaped honeycomb fired body, a coating step of coating at least a part of side surfaces of the honeycomb fired body with a paste-like bonding material, a honeycomb block body preparing step of bonding the plurality of honeycomb fired bodies while performing pressurizing, to prepare a honeycomb block body, and a circumference grinding step of grinding a circumferential surface of the honeycomb block body and obtaining the honeycomb structure, and in the honeycomb block body preparing step, the bonding is performed without interposing any member other than the bonding material between the honeycomb fired bodies, and the bonding material has a shear thinning property.

Abstract: The manufacturing method of the honeycomb structure has a forming step of forming a forming raw material into a plurality of quadrangular prismatic honeycomb formed bodies each having partition walls, a firing step of firing the plurality of honeycomb formed bodies to form a plurality of quadrangular prismatic honeycomb fired bodies, a sheet-like bonding material attaching step of attaching sheet-like bonding materials to at least part of side surfaces of at least part of the plurality of honeycomb fired bodies, a honeycomb block body preparing step of preparing a honeycomb block body in which the plurality of honeycomb fired bodies are stacked, by assembling the plurality of quadrangular prismatic honeycomb fired bodies while bonding the side surfaces thereof to one another by the bonding materials, and a grinding step of grinding a circumferential portion of the honeycomb block body to obtain the honeycomb structure.

Abstract: To provide a thin optical sheet having improved efficiency for light utilization, an optical sheet (5) of one mode of the present invention includes, in sequence from a light entry side to a light emission side, a plurality of first prisms (13), a ¼ wavelength plate (11), and a polarized-light separating element (12), the plurality of first prisms (13) each having (i) a first surface (13a) through which light enters the first prism and (ii) a second surface (13b) that reflects the light, having entered the first prism, toward the light emission side, the optical film further including, between the plurality of first prisms in an in-plane direction of the optical film, a second prism (14) that reflects light.

Abstract: A lighting device (100) includes: a surface light source (1); a first lens (L1) having a first focal point (F1), the first lens being provided on the light exit surface side of the surface light source; and a second lens (L2) having a second focal point (F2), the second lens being provided on a light exit surface side of the first lens, the surface light source, the first lens, and the second lens being configured such that a first virtual image (I1) is formed by the first lens and a second virtual image (I2) is formed by the second lens, wherein the first virtual image (I1) is formed between the second focal point (F2) and the first lens, the second focal point (F2) is on a side opposite to the light source side relative to a predetermined focal position f?, and at least either of a light entry surface or a light exit surface of the first lens or the second lens includes a non-revolution surface (SO) as a lens surface, and a plurality of boundary lines (B1-B4) whose curvatures vary discontinuously are provid