Patents by Inventor Yuzuru Mikami

Yuzuru Mikami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrolide compound JK
    Patent number: 6693085
    Abstract: Compound JK represented by the general formula (1): wherein R is H or —CH3; or a pharmaceutically acceptable salt thereof. Compound JK has an excellent antimicrobial activity even against resistant strains including MRSA and is useful as an anti-microbial agent.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: February 17, 2004
    Assignee: Higeta Shoyu Co., Ltd.
    Inventors: Yasushi Tanaka, Hisayuki Komaki, Akira Nemoto, Katsukiyo Yazawa, Yuzuru Mikami
  • Novel macrolide compound jk
    Publication number: 20030069193
    Abstract: Compound JK represented by the general formula (1): 1
    Type: Application
    Filed: October 26, 2001
    Publication date: April 10, 2003
    Inventors: Yasushi Tanaka, Hisayuki Komaki, Akira Nemoto, Katsukiyo Yazawa, Yuzuru Mikami
  • Macrolide compound 0406
    Patent number: 6090610
    Abstract: Compound 0406 having a chemical structural formula represented by the chemical formula (1) below and having an excellent immuno suppressive activity, and pharmaceutically acceptable salts thereof. ##STR1## (wherein R.sub.1 is --COCH.sub.2 COOH or H; R.sub.2 is --CO(CH.sub.2).sub.3 CH.sub.3 or --CO(CH.sub.2).sub.4 CH.sub.3 or H.
    Type: Grant
    Filed: January 29, 1999
    Date of Patent: July 18, 2000
    Assignee: Higeta Shoyu Co., Ltd.
    Inventors: Yasushi Tanaka, Hisayuki Komaki, Yuzuru Mikami, Katsukiyo Yazawa, Jun'ichi Kobayashi
  • Macrolide compound 0406
    Patent number: 6004995
    Abstract: Compound 0406 having a chemical structural formula represented by the chemical formula (1) below and having an excellent immuno suppressive activity, and pharmaceutically acceptable salts thereof. ##STR1## (wherein R.sub.1 is --COCH.sub.2 COOH or H; R.sub.2 is --CO(CH.sub.2).sub.3 CH.sub.3 or --CO(CH.sub.2).sub.4 CH.sub.3 or H.
    Type: Grant
    Filed: April 24, 1997
    Date of Patent: December 21, 1999
    Assignee: Higeta Shoyu Co., LTD.
    Inventors: Yasushi Tanaka, Hisayuki Komaki, Yuzuru Mikami, Katsukiyo Yazawa, Jun'ichi Kobayashi
  • Anthracycline compound 0624
    Patent number: 5965407
    Abstract: The present invention relates to compound 0624 having excellent antitumor activity and antimicrobial activity, which is represented by the general formula (1), and a pharmaceutically acceptable salt thereof. ##STR1## (wherein R represents H or COCH.sub.3.
    Type: Grant
    Filed: March 3, 1998
    Date of Patent: October 12, 1999
    Assignee: Higeta Shoyu Co. Ltd.
    Inventors: Yasushi Tanaka, Yuzuru Mikami, Katsukiyo Yazawa
  • Terpenoid compound 0406TP-1
    Patent number: 5932555
    Abstract: The present invention relates to compound 0406TP-1 represented by the general formula (I): ##STR1## wherein Ac represents an acetyl group and Me represents a methyl group, or a pharmaceutically acceptable salt thereof, having excellent antitumor activity and immunosuppressive activity.
    Type: Grant
    Filed: January 22, 1998
    Date of Patent: August 3, 1999
    Assignee: Higeta Shoyu Co., Ltd.
    Inventors: Hisayuki Komaki, Akira Nemoto, Yasushi Tanaka, Yuzuru Mikami, Katsukiyo Yazawa, Jun'ichi Kobayashi
  • Indole alkaloid type compound 0089-D
    Patent number: 5922582
    Abstract: The present invention relates to compound 0089-D having excellent antitumor activity and antimicrobial activity, represented by the general formula (I): ##STR1## or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: July 13, 1999
    Assignee: HIGETA SHOYU Co., Ltd.
    Inventors: Akira Nemoto, Yasushi Tanaka, Hisayuki Komaki, Yuzuru Mikami, Katsukiyo Yazawa, Jun'ichi Kobayashi
  • Novel saframycin A derivatives and process for producing the same
    Patent number: 4837149
    Abstract: Disclosed are compounds of the formula ##STR1## wherein R represents hydrogen or C.sub.1 -C.sub.4 -alkyl. These compounds are obtained by fermentation of the known saframycin A producing strain Streptomyces lavendulae No. 314 and by reaction with the amino acids L-tyrosine, L-methionine, glycine and HOOC-(CH)NH.sub.2 -CH.sub.2 -R. When R is hydrogen, saframycin Y.sub.3 and when R is methyl, saframycin Y.sub.d-1 are produced.
    Type: Grant
    Filed: September 22, 1987
    Date of Patent: June 6, 1989
    Assignee: Tadashi Arai
    Inventors: Tadashi Arai, Yuzuru Mikami