Patents by Inventor Yvonne Chen

Yvonne Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • APOPTOTIC ANTI-IGE ANTIBODIES
    Publication number: 20140115729
    Abstract: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
    Type: Application
    Filed: December 20, 2013
    Publication date: April 24, 2014
    Applicant: Genentech, Inc.
    Inventors: Lawren Wu, Mercedesz Balazs, Hans Brightbill, Andrew Chan, Yvonne Chen, Anan Chuntharapai, Mark Dennis, Terence Wong
  • Anti-CD79B Antibodies and Immunoconjugates and Methods of Use
    Publication number: 20140099260
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: August 22, 2013
    Publication date: April 10, 2014
    Applicant: Genentech, Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • Anti-CD79B antibodies and immunoconjugates and methods of use
    Patent number: 8691531
    Abstract: The present invention is directed to compositions of matter comprising nucleic acids encoding a polypeptide comprising the amino acid sequence of SEQ ID NO: 207 or 208, encoding an anti-CD79b antibody comprising the heavy chain variable domain sequence of SEQ ID NO: 207 and the light chain variable domain sequence of SEQ ID NO: 208, or encoding an anti-CD79b antibody having : (i) a variable light chain comprising a HVR-L1 having the sequence of SEQ ID NO: 194, a HVR-L2 having the sequence of SEQ ID NO: 195, and a HVR-L3 having the sequence of SEQ ID NO: 196 and (ii) a variable light chain comprising a HVR-H1 having the sequence of SEQ ID NO: 202, a HVR-H2 having the sequence of SEQ ID NO: 203, and a HVR-H3 having the sequence of SEQ ID NO: 204, and vectors and host cells thereof.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: April 8, 2014
    Assignee: Genentech, Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • Apoptotic anti-IgE antibodies
    Patent number: 8632775
    Abstract: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
    Type: Grant
    Filed: October 25, 2011
    Date of Patent: January 21, 2014
    Assignee: Genentech, Inc.
    Inventors: Lawren Wu, Mercedesz Balazs, Hans Brightbill, Andrew Chan, Yvonne Chen, Anan Chuntharapai, Mark Dennis, Terence Wong
  • Nucleic acid encoding apoptotic anti-IgE antibodies
    Patent number: 8618274
    Abstract: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
    Type: Grant
    Filed: October 25, 2011
    Date of Patent: December 31, 2013
    Assignee: Genentech, Inc.
    Inventors: Lawren Wu, Mercedesz Balazs, Hans Brightbill, Andy Chan, Yvonne Chen, Anan Chuntharapai, Mark Dennis, Terence Wong
  • Methods of using apoptotic anti-IGE antibodies
    Patent number: 8586040
    Abstract: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
    Type: Grant
    Filed: October 25, 2011
    Date of Patent: November 19, 2013
    Assignee: Genentech, Inc.
    Inventors: Lawren Wu, Mercedesz Balazs, Hans Brightbill, Andy Chan, Yvonne Chen, Anan Chuntharapai, Mark Dennis, Terence Wong
  • Anti-CD79B antibodies and immunoconjugates and methods of use
    Patent number: 8545850
    Abstract: The present invention is directed to compositions of matter comprising immunoconjugates comprising an anti-CD79b antibody comprising: (i) an HVR-L1 sequence of KASQSVDYEGDSFLN (SEQ ID NO: 194), (ii) an HVR-L2 sequence of AASNLES (SEQ ID NO: 195), (iii) an HVR-L3 sequence of QQSNEDPLT (SEQ ID NO: 196), (iv) an HVR-H1 sequence of GYTFSSYWIE (SEQ ID NO: 202), (v) an HVR-H2 sequence of GEILPGGGDTNYNEIFKG (SEQ ID NO: 203), and (vi) an HVR-H3 sequence of TRRVPIRLDY (SEQ ID NO: 204) and to methods of using those compositions of matter for the treatment of hematopoietic tumor in mammals.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: October 1, 2013
    Assignee: Genentech, Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • METHODS OF USING APOPTOTIC ANTI-IGE ANTIBODIES
    Publication number: 20120177635
    Abstract: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
    Type: Application
    Filed: October 25, 2011
    Publication date: July 12, 2012
    Applicant: GENENTECH, INC.
    Inventors: LAWREN WU, MERCEDESZ BALAZS, HANS BRIGHTBILL, ANDY CHAN, YVONNE CHEN, ANAN CHUNTHARAPAL, MARK DENNIS, TERENCE WONG
  • Nucleic acid encoding apoptotic anti-ige antibodies
    Publication number: 20120178127
    Abstract: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
    Type: Application
    Filed: October 25, 2011
    Publication date: July 12, 2012
    Applicant: Genentech, Inc.
    Inventors: Lawren Wu, Mercedesz Balazs, Hans Brightbill, Andrew Chan, Yvonne Chen, Anan Chuntharapai, Mark Dennis, Terence Wong
  • APOPTOTIC ANTI-IGE ANTIBODIES
    Publication number: 20120149881
    Abstract: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
    Type: Application
    Filed: October 25, 2011
    Publication date: June 14, 2012
    Applicant: Genentech, Inc.
    Inventors: Lawren Wu, Mercedesz Balazs, Hans Brightbill, Andrew Chan, Yvonne Chen, Anan Chuntharapai, Mark Dennis, Terence Wong
  • Anti-CD79B Antibodies and Immunoconjugates and Methods of Use
    Publication number: 20120148600
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: November 28, 2011
    Publication date: June 14, 2012
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • TRANSGENIC ANIMALS EXPRESSING HUMAN IGE-M1'
    Publication number: 20120144512
    Abstract: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
    Type: Application
    Filed: October 25, 2011
    Publication date: June 7, 2012
    Applicant: Genentech, Inc.
    Inventors: Lawren Wu, Mercedesz Balazs, Hans Brightbill, Andrew Chan, Yvonne Chen, Anan Chuntharapai, Mark Dennis, Terence Wong
  • Anti-CD79B antibodies and immunoconjugates and methods of use
    Patent number: 8088378
    Abstract: The present invention is directed to anti-CD79b antibody, huMA79b.v28, and compositions of matter thereof useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Grant
    Filed: July 15, 2008
    Date of Patent: January 3, 2012
    Assignee: Genetech Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • Apoptotic anti-IgE antibodies
    Patent number: 8071097
    Abstract: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: December 6, 2011
    Assignee: Genentech, Inc.
    Inventors: Lawren Wu, Mercedesz Balazs, Hans Brightbill, Andrew Chan, Yvonne Chen, Anan Chuntharapai, Mark Dennis, Terence Wong
  • ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE
    Publication number: 20110135667
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: November 5, 2010
    Publication date: June 9, 2011
    Applicant: GENENTECH, INC.
    Inventors: YVONNE CHEN, MARK DENNIS, DAVID DORNAN, KRISTI ELKINS, JAGATH REDDY JUNUTULA, ANDREW POLSON, BING ZHENG
  • ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE
    Publication number: 20100215669
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: January 14, 2009
    Publication date: August 26, 2010
    Applicant: Genentech, Inc.
    Inventors: Yvonne CHEN, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson
  • Selection of nucleic acid-based sensor domains within nucleic acid switch platform
    Publication number: 20090082217
    Abstract: The invention relates to a method (preferably a high throughput method) for screening for functional aptamer-regulated, ligand-responsive nucleic acids, or “ampliSwitches,” and uses thereof. The subject method not only applies to large molecules, such as proteins, but also applies to relatively small ligands, such as those with molecular weight of no more than 5 kDa, 3 kDa, or 1 kDa.
    Type: Application
    Filed: July 16, 2008
    Publication date: March 26, 2009
    Applicant: California Institute of Technology
    Inventors: Christina D. Smolke, Arwen Brown, Yvonne Chen, Midori Greenwood-Goodwin
  • Humanized Anti-CD79B Antibodies and Immunoconjugates and Methods of Use
    Publication number: 20090068202
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: July 15, 2008
    Publication date: March 12, 2009
    Applicant: Genentech, Inc.
    Inventors: Yvonne Chen, Mark Dennis, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • Anti-CD79B Antibodies and Immunoconjugates and Methods of Use
    Publication number: 20090028856
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: July 15, 2008
    Publication date: January 29, 2009
    Applicant: Genentech, Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • Apoptotic Anti-IgE Antibodies
    Publication number: 20090010924
    Abstract: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
    Type: Application
    Filed: March 21, 2008
    Publication date: January 8, 2009
    Applicant: GENENTECH, INC.
    Inventors: Lawren Wu, Mercedesz Balazs, Hans Brightbill, Andrew Chan, Yvonne Chen, Anan Chuntharapai, Mark Dennis, Terence Wong