Patents by Inventor Zdenek Polivka

Zdenek Polivka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists
    Patent number: 11420929
    Abstract: Phenoxy acetic acids and phenyl propionic acids and their use in improving mitochondrial energy output in a subject are provided herein. The present compounds are activators of PPAR? and may be useful for treating conditions mediated by the same.
    Type: Grant
    Filed: March 9, 2021
    Date of Patent: August 23, 2022
    Assignee: VTV THERAPEUTICS LLC
    Inventors: Per Sauerberg, Pavel Pihera, Zdenek Polivka, Miroslav Havranek, Ingrid Pettersson, John Patrick Mogensen
  • PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS
    Publication number: 20210188758
    Abstract: Phenoxy acetic acids and phenyl propionic acids and their use in improving mitochondrial energy output in a subject are provided herein. The present compounds are activators of PPAR? and may be useful for treating conditions mediated by the same.
    Type: Application
    Filed: March 9, 2021
    Publication date: June 24, 2021
    Inventors: Per SAUERBERG, Pavel PIHERA, Zdenek POLIVKA, Miroslav HAVRANEK, Ingrid PETTERSSON, John Patrick MOGENSEN
  • Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists
    Patent number: 10947180
    Abstract: Phenoxy acetic acids and phenyl propionic acids and their use in improving mitochondrial energy output in a subject are provided herein. The present compounds are activators of PPAR? and may be useful for treating conditions mediated by the same.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: March 16, 2021
    Assignee: VTV THERAPEUTICS LLC
    Inventors: Per Sauerberg, Pavel Pihera, Zdenek Polivka, Miroslav Havranek, Ingrid Petterson, John Patrick Mogensen
  • PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS
    Publication number: 20200215073
    Abstract: Phenoxy acetic acids and phenyl propionic acids and their use in improving mitochondrial energy output in a subject are provided herein. The present compounds are activators of PPAR? and may be useful for treating conditions mediated by the same.
    Type: Application
    Filed: November 8, 2019
    Publication date: July 9, 2020
    Inventors: Per SAUERBERG, Pavel PIHERA, Zdenek POLIVKA, Miroslav HAVRANEK, Ingrid PETTERSON, John Patrick MOGENSEN
  • Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists
    Patent number: 10471066
    Abstract: Phenoxy acetic acids and phenyl propionic acids and their use in improving mitochondrial energy output in a subject are provided herein. The present compounds are activators of PPAR? and may be useful for treating conditions mediated by the same.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: November 12, 2019
    Assignee: VTV THERAPEUTICS LLC
    Inventors: Per Sauerberg, Pavel Pihera, Zdenek Polivka, Miroslav Havranek, Ingrid Pettersson, John Patrick Mogensen
  • Phenoxy Acetic Acids and Phenyl Propionic Acids as PPAR Delta Agonists
    Publication number: 20180071304
    Abstract: Phenoxy acetic acids and phenyl propionic acids and their use in improving mitochondrial energy output in a subject are provided herein. The present compounds are activators of PPAR? and may be useful for treating conditions mediated by the same.
    Type: Application
    Filed: November 20, 2017
    Publication date: March 15, 2018
    Inventors: Per Sauerberg, Pavel Pihera, Zdenek Polivka, Miroslav Havranek, Ingrid Pettersson, John Patrick Mogensen
  • Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists
    Patent number: 9855274
    Abstract: Phenoxy acetic acids and phenyl propionic acids and their use in treating type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, or obesity are provided herein. The present compounds are activators of PPAR? and may be useful for treating conditions mediated by the same.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: January 2, 2018
    Assignee: vTv Therapeutics LLC
    Inventors: Per Sauerberg, Pavel Pihera, Zdenek Polivka, Miroslav Havranek, Ingrid Pettersson, John Patrick Mogensen
  • PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS
    Publication number: 20170216303
    Abstract: Phenoxy acetic acids and phenyl propionic acids and their use in treating type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, or obesity are provided herein. The present compounds are activators of PPAR? and may be useful for treating conditions mediated by the same.
    Type: Application
    Filed: April 18, 2017
    Publication date: August 3, 2017
    Inventors: Per Sauerberg, Pavel Pihera, Zdenek Polivka, Miroslav Havranek, Ingrid Pettersson, John Patrick Mogensen
  • Phenoxy acetic acids and phenyl propionic acids as PPAR? agonists
    Patent number: 9663481
    Abstract: Phenoxy acetic acids and phenyl propionic acids and their use in treating type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, or obesity are provided herein. The present compounds are activators of PPAR? and may be useful for treating conditions mediated by the same.
    Type: Grant
    Filed: September 3, 2013
    Date of Patent: May 30, 2017
    Assignee: vTv Therapeutics LLC
    Inventors: Per Sauerberg, Pavel Pihera, Zdenek Polivka, Miroslav Havranek, Ingrid Pettersson, John Patrick Mogensen
  • PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS
    Publication number: 20140024645
    Abstract: Phenoxy acetic acids and phenyl propionic acids and their use in treating type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, or obesity are provided herein. The present compounds are activators of PPAR? and may be useful for treating conditions mediated by the same.
    Type: Application
    Filed: September 3, 2013
    Publication date: January 23, 2014
    Applicant: High Point Pharmaceuticals, LLC
    Inventors: Per Sauerberg, Pavel Pihera, Zdenek Polivka, Miroslav Havranek, Ingrid Pettersson, John Patrick Mogensen
  • Phenoxy acetic acids as PPAR delta activators
    Patent number: 8551993
    Abstract: Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds are activators of PPAR? and should be useful for treating conditions mediated by the same.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: October 8, 2013
    Assignee: High Point Pharmaceuticals, LLC
    Inventors: Per Sauerberg, Pavel Pihera, Zdenek Polivka, Miroslav Havranek, Ingrid Pettersson, John Patrick Mogensen
  • Phenyl propionic acids as PPAR delta activators
    Patent number: 8362016
    Abstract: Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds are activators of PPAR? and should be useful for treating conditions mediated by the same.
    Type: Grant
    Filed: April 4, 2011
    Date of Patent: January 29, 2013
    Assignee: High Point Pharmaceuticals, LLC
    Inventors: Per Sauerberg, Pavel Pihera, Zdenek Polivka, Miroslav Havranek, Ingrid Pettersson, John Patrick Mogensen
  • Compounds, their preparation and use
    Patent number: 8053598
    Abstract: Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator-Activated Receptors (PPAR), in particular the PPAR? subtype.
    Type: Grant
    Filed: May 3, 2005
    Date of Patent: November 8, 2011
    Assignee: High Point Pharmaceuticals, LLC
    Inventor: Zdenék Polivka
  • PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS
    Publication number: 20110245244
    Abstract: Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds are activators of PPAR? and should be useful for treating conditions mediated by the same.
    Type: Application
    Filed: April 4, 2011
    Publication date: October 6, 2011
    Applicant: HIGH POINT PHARMACEUTICALS, LLC
    Inventors: Per Sauerberg, Pavel Pihera, Zdenek Polivka, Miroslav Havranek, Ingrid Pettersson, John Patrick Mogensen
  • Compounds, their preparation and use
    Patent number: 7943613
    Abstract: Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds are activators of PPAR? and should be useful for treating conditions mediated by the same.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: May 17, 2011
    Assignee: High Point Pharmaceuticals, LLC
    Inventors: Per Sauerberg, Pavel Pihera, Zdenek Polivka, Miroslav Havranek, Ingrid Pettersson, John Patrick Mogensen
  • Novel compounds, their preparation and use
    Publication number: 20110039841
    Abstract: Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator-Activated Receptors (PPAR), in particular the PPAR? subtype.
    Type: Application
    Filed: May 3, 2005
    Publication date: February 17, 2011
    Applicants: Novo Nordisk A/S
    Inventors: Zdenék Polivka, Karel Sindelar, Per Sauerberg, Ingrid Pettersson
  • Dimeric dicarboxylic acid derivatives, their preparation and use
    Patent number: 7816385
    Abstract: A novel class of dicarboxylic acid derivatives, the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator -Activated Receptors (PPAR).
    Type: Grant
    Filed: December 12, 2003
    Date of Patent: October 19, 2010
    Assignee: High Point Pharmaceuticals, LLC
    Inventors: Per Sauerberg, Lone Jeppesen, Zdenek Polivka, Karel Sindelar
  • NOVEL COMPOUNDS, THEIR PREPARATION AND USE
    Publication number: 20090093484
    Abstract: Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds are activators of PPAR? and should be useful for treating conditions mediated by the same.
    Type: Application
    Filed: December 21, 2006
    Publication date: April 9, 2009
    Inventors: Per Sauerberg, Pavel Pihera, Zdenek Polivka, Miroslav Havranek, Ingrid Pettersson, John Patrick Mogensen
  • Novel Compounds, Their Preparation and Use
    Publication number: 20090012171
    Abstract: Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator-Activated Receptors (PPAR), in particular the PPAR? subtype.
    Type: Application
    Filed: May 3, 2005
    Publication date: January 8, 2009
    Applicant: NOVO NORDISK A/S
    Inventor: Zdenek Polivka
  • Novel compounds, their preparation and use
    Publication number: 20040259950
    Abstract: A novel class of dicarboxylic acid derivatives, the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator-Activated Receptors (PPAR).
    Type: Application
    Filed: December 12, 2003
    Publication date: December 23, 2004
    Inventors: Per Sauerberg, Lone Jeppesen, Zdenek Polivka, Karel Sindelar