Patents by Inventor Zhonghui Hugh Fan

Zhonghui Hugh Fan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190154550
    Abstract: Described herein are bioaerosol detection systems and methods of use.
    Type: Application
    Filed: April 6, 2017
    Publication date: May 23, 2019
    Inventors: Chang-Yu WU, Xiao JIANG, Maohua PAN, John LEDNICKY, Alexandros Demetrios THEODORE, Zhonghui Hugh FAN, Nima AFSHAR MOHAJER
  • Patent number: 10214713
    Abstract: The current is directed to a device comprising, a reaction chamber where a reaction takes place, one or more feeding chambers which contain feeding solution comprising chemicals required for the reaction, and one or more porous membranes separating the reaction chamber from the one or more feeding chambers, and wherein the one or more porous membranes are in substantially vertical position. The current invention is also directed to an apparatus comprising a plurality of devices, wherein each device comprises of a reaction chamber where a reaction takes place, one or more feeding chambers which contain feeding solution comprising chemicals required for the reaction, and one or more porous membranes which separate the reaction chamber from feeding chambers, wherein the one or more porous membranes are in substantially vertical position. These devices and apparatuses can be used for high throughput synthesis of biomolecules and chemicals and biological screening assays.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: February 26, 2019
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
    Inventors: Zhonghui Hugh Fan, Kirsten Marie Jackson
  • Publication number: 20160291023
    Abstract: The subject invention pertains to devices and methods of isolating target cells from a population of cells. The devices comprise of microfluidic channels and aptamers and antibodies attached to the inner surface of the microfluidic channels, wherein the aptamers and the antibodies are capable of specific binding to one or more biomolecules present on the surface of the target cell. The methods of the current invention comprise passing the population of cells through the microfluidic channels to facilitate interaction and capture of the target cells by the aptamers and the antibodies attached to the inner surface of the microfluidic channels, washing to microfluidic channels by a washing solution to remove the cells non-specifically bound to the aptamers and the antibodies attached to the inner surface of the microfluidic channels, releasing the captured target cells from the microfluidic channels, and collecting the released target cells.
    Type: Application
    Filed: November 20, 2014
    Publication date: October 6, 2016
    Inventors: ZHONGHUI HUGH FAN, JINLING ZHANG
  • Publication number: 20160168526
    Abstract: The current is directed to a device comprising, a reaction chamber where a reaction takes place, one or more feeding chambers which contain feeding solution comprising chemicals required for the reaction, and one or more porous membranes separating the reaction chamber from the one or more feeding chambers, and wherein the one or more porous membranes are in substantially vertical position. The current invention is also directed to an apparatus comprising a plurality of devices, wherein each device comprises of a reaction chamber where a reaction takes place, one or more feeding chambers which contain feeding solution comprising chemicals required for the reaction, and one or more porous membranes which separate the reaction chamber from feeding chambers, wherein the one or more porous membranes are in substantially vertical position. These devices and apparatuses can be used for high throughput synthesis of biomolecules and chemicals and biological screening assays.
    Type: Application
    Filed: July 17, 2014
    Publication date: June 16, 2016
    Applicant: Universtiy of Florida Research Foundation, Inc.
    Inventors: Zhonghui Hugh Fan, Kirsten Marie Jackson
  • Publication number: 20160091489
    Abstract: The subject invention pertains to devices and methods of isolating target cells from a population of cells. The devices comprise of one or more microfluidic channels and scaffolding particles conjugated with one or more ligands that bind to the target cells. The scaffolding particles with one or more ligands are attached on to the surface of the one or more microfluidic channels. The methods of the current invention comprise passing the population of cells through the microfluidic channels of the devices of the current invention to facilitate interaction and capture of the target cells by the scaffolding particles-ligand conjugates, washing the device by a washing solution to remove the cells non-specifically bound to the scaffolding particle-ligand conjugates, releasing the captured target cells from the scaffolding particle-ligand conjugates, and collecting the released target cells.
    Type: Application
    Filed: June 3, 2014
    Publication date: March 31, 2016
    Inventors: ZHONGHUI HUGH FAN, WEIAN SHENG, TAO CHEN, WEIHONG TAN
  • Publication number: 20030039868
    Abstract: Provided is a battery comprising a first compartment, a second compartment and a barrier separating the first and second compartments, wherein the barrier comprises a proton transporting moiety.
    Type: Application
    Filed: August 23, 2002
    Publication date: February 27, 2003
    Inventors: Michael James Liberatore, Leszek Hozer, Attiganal Narayanaswamy Sreeram, Rajan Kumar, Chetna Bindra, Zhonghui Hugh Fan
  • Patent number: 6500571
    Abstract: Provided is a fuel cell comprising a first compartment, a second compartment and a barrier separating the first and second compartments, wherein the barrier comprises a proton transporting moiety.
    Type: Grant
    Filed: August 18, 1999
    Date of Patent: December 31, 2002
    Assignee: PowerZyme, Inc.
    Inventors: Michael James Liberatore, Leszek Hozer, Attiganal Narayanaswamy Sreeram, Rajan Kumar, Chetna Bindra, Zhonghui Hugh Fan
  • Publication number: 20020001739
    Abstract: Provided is a battery comprising a first compartment, a second compartment and a barrier separating the first and second compartments, wherein the barrier comprises a proton transporting moiety.
    Type: Application
    Filed: August 18, 1999
    Publication date: January 3, 2002
    Inventors: MICHAEL JAMES LIBERATORE, LESZEK HOZER, ATTIGANAL NARAYANASWAMY SREERAM, RAJAN KUMAR, CHETNA BINDRA, ZHONGHUI HUGH FAN
  • Patent number: 6296752
    Abstract: Provided is an apparatus for separating, in a medium, a component from a composition comprising: (1) an array of three or more electrodes arrayed along a pathway along which molecules of the composition are transported; and (2) a power source device for delivering to voltage to the electrodes; wherein the voltages delivered to the electrode array by the power source device are effective to: (a) alter the relative movement along the transport pathway of two or more of the molecules caused by a motive force, or (b) cause the molecules to move along the transport pathway.
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: October 2, 2001
    Assignee: Sarnoff Corporation
    Inventors: Sterling Eduard McBride, Satyam Choudary Cherukuri, Rajan Kumar, Judith Ann Ladd, Zhonghui Hugh Fan, Bryan Lloyd Bentz, Peter J. Zanzucchi
  • Patent number: 5992820
    Abstract: Provided is a fluid control device comprising: (a) a channel of capillary dimensions for conveying a liquid, (b) a bubble-forming device for forming a channel-blocking bubble in the channel, wherein such a bubble formed in the channel impedes the flow of the liquid through the channel.
    Type: Grant
    Filed: November 19, 1997
    Date of Patent: November 30, 1999
    Assignee: Sarnoff Corporation
    Inventors: Thomas Louis Fare, Zhonghui Hugh Fan, Paul James Heaney
  • Patent number: 5846396
    Abstract: The present invention provides a liquid distribution system, which is useful in a number of contexts, including in accomplishing various synthetic, diagnostic and drug screening reactions. The distribution system can comprise an alpha reservoir and a beta reservoir, a first set of parallel and adjacent first and second feeder channels and a second set of parallel and adjacent third and fourth feeder channels which are offset from the first and second feeder channels, wherein (a) the first and third feeder channels are connected to the alpha reservoir via a first connector channel that is situated above or below the second and fourth feeder channels and are independent of the beta reservoir and (b) the second and fourth feeder channels are connected to the beta reservoir via a second connector channel that is situated above or below the first and third feeder channels and are independent of the alpha reservoir. The distribution system is preferably a microscale distribution system.
    Type: Grant
    Filed: November 9, 1995
    Date of Patent: December 8, 1998
    Assignee: Sarnoff Corporation
    Inventors: Peter John Zanzucchi, Satyam Choudary Cherukuri, Sterling Edward McBride, Robert R. Demers, Aaron W. Levine, Barry Jay Thaler, Robert Leon Quinn, Paul Leonard Braun, William Chiang, Zhonghui Hugh Fan, Steven A. Lipp, James R. Matey