Patents by Inventor Zhuyan Guo

Zhuyan Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7504424
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate, ester or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof.
    Type: Grant
    Filed: January 17, 2006
    Date of Patent: March 17, 2009
    Assignee: Schering Corporation
    Inventors: Wensheng Yu, Ling Tong, Lei Chen, Joseph A. Kozlowski, Brian J. Lavey, Neng-Yang Shih, Vincent S. Madison, Guowei Zhou, Peter Orth, Zhuyan Guo, Michael K. C. Wong, De-Yi Yang, Seong Heon Kim, Bandarpalle B. Shankar, M. Arshad Siddiqui, Kristin E. Rosner, Chaoyang Dai, Umar Faruk Mansoor, Janeta Popovici-Muller, Vinay M. Girijavallabhan, Dansu Li
  • Patent number: 7488745
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate, ester or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: February 10, 2009
    Assignee: Schering Corporation
    Inventors: Wensheng Yu, Ling Tong, Lei Chen, Joseph A. Kozlowski, Brian J. Lavey, Neng-Yang Shih, Vincent S. Madison, Guowei Zhou, Peter Orth, Zhuyan Guo, Michael K. C. Wong, De-Yi Yang, Seong Heon Kim, Bandarpalle B. Shankar, M. Arshad Siddiqui, Kristin E. Rosner, Chaoyang Dai, Janeta Popovici-Muller, Vinay M. Girijavallabhan, Dansu Li, Razia Rizvi, Aneta M. Micula, Robert Feltz
  • Patent number: 7482370
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, TNF- or combinations thereof.
    Type: Grant
    Filed: July 13, 2005
    Date of Patent: January 27, 2009
    Assignee: Schering Corporation
    Inventors: Wensheng Yu, Ling Tong, Lei Chen, Joseph A. Kozlowski, Brian J. Lavey, Neng-Yang Shih, Vincent S. Madison, Guowei Zhou, Peter Orth, Zhuyan Guo, Michael K. C. Wong, De-Yi Yang, Seong Heon Kim, Bandarpalle B. Shankar
  • Publication number: 20080004287
    Abstract: In its many embodiments, the present invention discloses novel compounds, as inhibitors of HDM2 protein, methods for preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of treatment, prevention, inhibition, of one or more diseases associated with the HDM2 protein or P53 using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: June 27, 2007
    Publication date: January 3, 2008
    Inventors: Yao Ma, Brian Lahue, Gerald Shipps, Yaolin Wang, Stephane Bogen, Matthew Voss, Latha Nair, Yuan Tian, Ronald Doll, Zhuyan Guo, Corey Strickland, Rumin Zhang, Mark McCoy, Weidong Pan, Elise Siegel, Craig Gibeau
  • Publication number: 20070219218
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate, ester or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof.
    Type: Application
    Filed: January 16, 2007
    Publication date: September 20, 2007
    Inventors: Wensheng Yu, Ling Tong, Lei Chen, Joseph Kozlowski, Brian Lavey, Neng-Yang Shih, Vincent Madison, Guowei Zhou, Peter Orth, Zhuyan Guo, Michael Wong, De-Yi Yang, Seong Kim, Bandarpalle Shankar, M. Siddiqui, Kristin Rosner, Chaoyang Dai, Janeta Popovici-Muller, Vinay Girijavallabhan, Dansu Li, Razia Rizvi, Aneta Micula, Robert Feltz
  • Publication number: 20060276506
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate, ester or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof.
    Type: Application
    Filed: January 17, 2006
    Publication date: December 7, 2006
    Inventors: Wensheng Yu, Ling Tong, Lei Chen, Joseph Kozlowski, Brian Lavey, Neng-Yang Shih, Vincent Madison, Guowei Zhou, Peter Orth, Zhuyan Guo, Michael Wong, De-Yi Yang, Seong Kim, Bandarpalle Shankar, M. Siddiqui, Kristin Rosner, Chaoyang Dai, Umar Mansoor, Janeta Popovici-Muller, Vinay Girijavallabhan, Dansu Li
  • Publication number: 20060252778
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, TNF-? or combinations thereof.
    Type: Application
    Filed: June 1, 2005
    Publication date: November 9, 2006
    Inventors: Zhuyan Guo, Peter Orth, Zhaoning Zhu, Robert Mazzola, Tin-Yau Chan, Henry Vaccaro, Brian McKittrick, Joseph Kozlowski, Brian Lavey, Guowei Zhou, Sunil Paliwal, Shing-Chun Wong, Neng-Yang Shih, Pauline Ting, Kristin Rosner, Gerald Shipps, M. Siddiqui, David Belanger, Chaoyang Dai, Dansu Li, Vinay Girijavallabhan, Janeta Popovici-Muller, Wensheng Yu, Lianyun Zhao
  • Publication number: 20060205797
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, TNF—combinations thereof.
    Type: Application
    Filed: July 13, 2005
    Publication date: September 14, 2006
    Inventors: Wensheng Yu, Ling Tong, Lei Chen, Joseph Kozlowski, Brian Lavey, Neng-Yang Shih, Vincent Madison, Guowei Zhou, Peter Orth, Zhuyan Guo, Michael Wong, De-Yi Yang, Seong Kim, Bandarpalle Shankar
  • Patent number: 7034057
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, TNF-? or combinations thereof.
    Type: Grant
    Filed: November 19, 2003
    Date of Patent: April 25, 2006
    Assignee: Schering Corporation
    Inventors: Zhaoning Zhu, Robert Mazzola, Zhuyan Guo, Brian J. Lavey, Lisa Sinning, Joseph Kozlowski, Brian McKittrick, Neng-Yang Shih
  • Publication number: 20060063843
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, TNF-? or combinations thereof.
    Type: Application
    Filed: October 20, 2005
    Publication date: March 23, 2006
    Inventors: Zhaoning Zhu, Robert Mazzola, Zhuyan Guo, Brian Lavey, Lisa Sinning, Joseph Kozlowski, Brian McKittrick, Neng-Yang Shih
  • Patent number: 6838466
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, TNF-? or combinations thereof.
    Type: Grant
    Filed: December 19, 2002
    Date of Patent: January 4, 2005
    Assignee: Schering Corporation
    Inventors: Zhaoning Zhu, Robert Mazzola, Zhuyan Guo, Brian J. Lavey, Lisa Sinning, Joseph Kozlowski, Brian McKittrick, Neng-Yang Shih
  • Publication number: 20040102418
    Abstract: This invention relates to compounds of the Formula (I): 1
    Type: Application
    Filed: November 19, 2003
    Publication date: May 27, 2004
    Inventors: Zhoaning Zhu, Robert Mazzola, Zhuyan Guo, Brian J. Lavey, Lisa Sinning, Joseph Kozlowski, Brian McKittrick, Neng-Yang Shih
  • Publication number: 20040038941
    Abstract: This invention relates to compounds of the Formula (I): 1
    Type: Application
    Filed: December 19, 2002
    Publication date: February 26, 2004
    Applicant: Schering Corporation
    Inventors: Zhaoning Zhu, Robert Mazzola, Zhuyan Guo, Brian J. Lavey, Lisa Sinning, Joseph Kozlowski, Brian McKittrick, Neng-Yang Shih
  • Publication number: 20030134846
    Abstract: Disclosed is a method of treating and or preventing infections of Trypanosoma brucei by administering to a patient, in need of such treatment, an effective amount of a Farnesyl Protein Transferase Inhibitor alone or in combination with an additional anti-Trypanosoma brucei agent and/or an anti-Trypanosoma brucei resistance reversing agent.
    Type: Application
    Filed: October 7, 2002
    Publication date: July 17, 2003
    Applicant: Schering Corporation
    Inventors: William T. Windsor, Patricia C. Weber, Corey Strickland, Rosalinda Syto, Viyyoor M. Girijavallabhan, James J. Kaminski, Zhuyan Guo