Patents by Inventor Zoltan Tuba

Zoltan Tuba has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-Amino-17a-aza-D-homoandrostane compounds, and pharmaceutical compositions containing them
    Patent number: 4200636
    Abstract: The invention relates to new 3-amino-17a-aza-D-homo-5.alpha.-androstane derivatives of the general formula I ##STR1## wherein R.sub.1 represents a methylene or an >N--CH.sub.3 group, and n stands for 1 or 2, and the acid addition salts and the quaternary salts of the general formula ##STR2## thereof, wherein R.sub.2 stands for an alkyl or alkenyl group having from 1 to 4 carbon atoms, and A represents a halogen atom, provided that if R.sub.1 stands for an >N--CH.sub.3 group, R.sub.2 is attached to the nitrogen of that >N--CH.sub.3 group. The new compound possess a non-polarizing neuromuscular blocking activity and have a short activity period.
    Type: Grant
    Filed: August 17, 1978
    Date of Patent: April 29, 1980
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Zoltan Tuba, Maria Marsai, Sandor Gorog, Katalin Biro, Egon Karpati, Laszlo Szporny
  • Diamino-androstanes and a process for the preparation of the said compounds
    Patent number: 4177190
    Abstract: Curare-type salts of the formula ##STR1## wherein Ac is an alkyl carbonyl group containing 1 to 4 carbon atoms in the alkyl moiety and one ofR.sub.1 and R.sub.2, is a methylene group and the other is a group of the formula >N--R.sub.2 wherein R.sub.2 is an alkyl group containing 1 to 3 carbon atoms,A is halogen andR.sub.3 is an alkyl group containing 1 to 4 carbon atoms, or an alkyl group; anda process for the preparation thereof are disclosed.
    Type: Grant
    Filed: March 14, 1978
    Date of Patent: December 4, 1979
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Zoltan Tuba, Maria Marsai, Katalin Biro, Laszlo Szporny, Egon Karpati, Szabolcs Szeberenyi
  • Diepoxy-androstanes and a process for the preparation thereof
    Patent number: 4171306
    Abstract: 5.alpha., 17B-Diacetoxy-6 -chloro-2.alpha., 3.alpha.; 16.alpha., 17.alpha.-diepoxy-androstane; 5.alpha., 17B-Dicetoxy-6 -chloro-androsta-2,16-diene; 5.alpha.-Hydroxy-6 -chloro-17-oxo-androst-2-ene or a like intermediate in the production of curare-like compounds is produced by reacting 5.alpha., 6B-dihydroxy-17-oxo-androst-2-ene with an organic sulfonic acid chloride. The obtained 5.alpha.- hydroxy-6B-chloro-17-oxo-androst-2-ene can then be reacted with the enol acetate of a ketone having 3 to 5 carbon atoms to yield 5.alpha., 17B-diacetoxy-6B-chloro-androsta-2,16-diene. The latter is treated to yield the corresponding diepoxide.
    Type: Grant
    Filed: January 25, 1977
    Date of Patent: October 16, 1979
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Zoltan Tuba, Maria Marsai
  • Acylated diepoxy-androstane and a process for the preparation thereof
    Patent number: 4110326
    Abstract: A compound of the formula (I) ##STR1## wherein X is a halogen,Z.sub.1 and Z.sub.2 are both hydrogen, orZ.sub.1 is hydroxy and Z.sub.2 is chlorine, orZ.sub.1 and Z.sub.2 together stand for an .alpha.-epoxy group.
    Type: Grant
    Filed: January 25, 1977
    Date of Patent: August 29, 1978
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt
    Inventors: Zoltan Tuba, Maria Marsai
  • Diamino-androstanes and a process for the preparation of the said compounds
    Patent number: 4101545
    Abstract: Curare-type salts of the formula ##STR1## WHEREIN Ac is an alkyl carbonyl group containing 1 to 4 carbon atoms in the alkyl moiety and one ofR.sub.1 and R.sub.2, is a methylene group and the other is a group of the formula >N-R.sub.2 wherein R.sub.2 is an alkyl group containing 1 to 3 carbon atoms,A is halogen andR.sub.3 is an alkyl group containing 1 to 4 carbon atoms, or an alkyl group; andA process for the preparation thereof are disclosed.
    Type: Grant
    Filed: July 28, 1976
    Date of Patent: July 18, 1978
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Zoltan Tuba, Maria Marsai, Katalin Biro, Laszlo Szporny, Egon Karpati, Szaboles Szeberenyi
  • Triamino-androstanes and a process for the preparation of the said compounds
    Patent number: 4071515
    Abstract: New triamino-androstanes with curare-type properties and a process for the preparation thereof are disclosed.
    Type: Grant
    Filed: July 28, 1976
    Date of Patent: January 31, 1978
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Zoltan Tuba, Maria Marsai, Katalin Biro, Laszlo Szporny, Egon Karpati, Szabolcs Szeberenyi