Abstract: The instant invention is directed to a method for producing hollow articles which are open toward the axis, are rotationally symmetrical and symmetrical with respect to a central plane produced from polyurethane multi-component reaction materials by the reaction casting method, a mold core being required during production for generating the cavity in the article, and the reaction mixture being supplied from the rotational axis via feed channels to a mold cavity, comprising: supplying a reaction mixture alternately to each side of the mold cavity, the article thus being built up symmetrically with respect to the rotational axis.

Abstract: Disclosed is an improved process for the production of organic polyisocyanate based molded polymers prepared from at least one organic polyisocyanate and at least one polyol in the presence of an internal release agent wherein the improvement comprises employing as said agent a polysiloxane having at least one unit of the formula ##STR1## wherein R is selected from the group consisting of lower-alkyl and aryl, R.sup.1 is a divalent hydrocarbon radical, and R.sup.2 is selected from the group consisting of lower-alkoxy, aryloxy, particular hydroxyalkyleneoxy, alkoxyalkyleneoxy, amino, and hydroxyalkylamino radicals.The molding process can be repeated in many cycles before the molds require cleaning or treatment with release agent. The ease and rapidity with which the present process can be carried out makes it particularly suited to RIM production methods.

Abstract: A method of making a body cavity insert, e.g. an ear insert, comprises deforming by pressure a pressure deformable sheet of material over an impression of a body cavity, e.g. an ear canal, and separating the impression from the sheet of material without permanently disturbing the shape into which the sheet has been deformed to leave a mould cavity in the sheet of material. A moulding material is then introduced into the mould cavity to provide, when the moulding material solidifies, the body cavity insert.Typically the pressure deformable sheet of material is a sheet of non-toxic, thermoplastics material, e.g. a polycarbonate or silicon rubber material. One example of a suitable moulding material is an acrylic plastics material.

Abstract: A tubular film process wherein molten resin is extruded from an extrusion die into a tubular resin, blown by an internal pressure, cooling air is discharged at least at a point between the vicinity of the extrusion die and the vicinity of a bubble expansion ending point in a direction of the extrusion of the resin and in a direction opposite to the extrusion of the resin to, thereby cool the tubular resin, and the tubular resin is continuously taken up upon being cooled and solidified. The cooling air has higher flow rate in the extrusion direction. The cooling air is discharged not only in the direction of the extrusion of the resin but also in the direction opposite to the extrusion of the resin, whereby hot air stream is prevented from accompanying the flow of the resin, thus enabling to effectively cool the tubular resin.

Abstract: Disclosed is a segmented toroidal field coil for use in a tokamak-type reactor and a method for forming the coil. Each toroidal field coil winding is segmented into two or more segments with a connection means provided at the end of each segment for electrically connecting the segments together and for joining consecutive adjacent segments. The coil segments are electrically conducting and will, therefore, induce a toroidal magnetic field when its feed points are connected to a power source. The toroidal field coil of the present invention maximizes heat flow from the plasma region of the reactor to the external blanket by eliminating bulky crossover connections from coil to coil that could otherwise restrict the heat flow. The present invention discloses a simple and efficient method for forming a toroidal field coil assembly that eliminates costly final machining such as precision twisting.

Abstract: A load control system for a boiling water reactor power plant. A recirculating pump speed demand signal and a total steam flow demand signal are derived on the basis of combination of a first control signalproduced in accordance with a power difference signal representative of difference between an actual value of an output power of an electric generator and a set value for the generator output and a second control signal produced in accordance with a pressure difference signal representative of difference between an actually measured value of the reactor pressure and a set value therefor. Speed of a recirculating pump is controlled in dependence on the recirculating pump speed demand signal, while opening degrees of a governor valve and a bypass valve of a turbine are controlled in accordance with the total steam flow demand signal.

Abstract: An ultrasonic flaw detector device including axial and circumferential fixed tracks located in a space defined between a pressure vessel of a nuclear reactor and a heat insulating wall surrounding the vessel and arranged axially and circumferentially respectively of the pressure vessel of the nuclear reactor. A rotary track is located at a junction of the axial fixed track and the circumferential fixed track and moved in rotary movement by a chain and has its angle of rotation restricted by a pair of stoppers. A carrier member supporting an ultrasonic probe is moved on the tracks to effect ultrasonic flaw detection to detect any flow that might be present in the pressure vessel. To transfer the carrier member from the axial fixed track to the circumferential fixed track, the carrier member is first transferred from the axial fixed track to the rotatable track, and after the rotary track is rotated, the carrier member is transferred from the rotatable track to the circumferential fixed track.

Abstract: There is described a container for the long time storage of radioactive materials, especially spent fuel elements, in suitable geological formations which guarantees an intact barrier for a long period of time even in the event of intrusion or access of water and brine. The container is provided with a cathodic corrosion protection whereby an isotope battery serves as the source of direct current. The radioactive stored materials is used as the source of energy.

Abstract: A device for providing translatory movement of the control rods inside the closed vessel of a nuclear reactor. The rotor of the drive motor for a screw/nut assembly has fixed to it two pivoting arms formed in the poles of the rotor, and these serve as latching members which keep the screw in its raised position. A tubular casing locks these arms in the opened position while the screw is being raised after the control rod has been allowed to fall into the core of the reactor.

Abstract: Reactor building comprising a vessel shaft anchored in a slab which is peripherally locked.This reactor building comprises a confinement enclosure (4) within which are positioned internal structures (14) constituted by an internal structure floor (16), a vessel shaft (18), a slab (22) being positioned between the general floor (8) and the internal structure floor (16), the vessel shaft (18) being anchored in the slab which is peripherally locked against the low part of the confinement enclosure skirt (12), a horizontal sliding joint (24) being positioned between slab (22) and internal structure floor (16).Application to the construction of the internal structures of a reactor building.

Abstract: A valve seat or similar article produced by sintering a compound body is improved in economy and producibility by employing a method wherein the amount of a second powder for forming the compound body is controlled so as to be minimized. A first powder is initially charged into a compression space and lightly compressed to form a preparatory compact of a desired shape. Subsequently, the second powder is charged in over the preparatory compact to a degree controlled by the displacement of the compact, and the preparatory compact and the second powder are forcefully compressively integrally molded to form a final compact which is then sintered to form the finished product.

Abstract: Metal-ceramic composites may be prepared by treating the ceramic component of the composite with a second metal prior to subjecting the metal-ceramic composite to a sintering operation. By pretreating the ceramic component of the composite, it is possible to obtain a composite which will undergo sintering at an elevated temperature to form a composite which will possess desirable characteristics such as increased density, hardness and low thermal coefficient of expansion, thus enabling the composites to be utilized in a wide variety of applications.

Abstract: The present invention relates to an automatic device for analyzing successive samples which comprises a turning plate provided at its periphery with vertical sockets containing a small tube filled with the sample to be analyzed, a photomultiplier arranged opposite the lateral face of the plate comprising an orifice communicating with the sockets, a first flat seal adapted to be actuated by a ring to be brought into contact with the lateral face of the plate, a second flat seal adapted to be actuated by another ring above the socket and a third seal carried by a movable cradle below the socket.

Abstract: A gas detector badge for detecting harmful gases, including a gas sensitive tape positioned behind a front panel, having an indicator window, a reference window and a control window. The control window is provided with a gas filter, whereas the indicator window is open to the atmosphere to permit harmful gas to pass through the indicator window to the gas sensitive tape; the reference window includes a gas impermeable member to protect the tape from the atmosphere. Harmful gases contacting the badge pass through the indicator window and the control window, passing through the latter at a slower rate, to chemically react with the tape to develop color as a measure of the harmful gases in the atmosphere.

Abstract: An on-line and continuous sampling system for monitoring the ionic content of steam-producing water in a steam-operated electrical power plant. The monitoring system comprises a plurality of sampling lines and associated apparatus for sampling the steam-producing water at a number of different points in the power plant, an ion chromatographic subsystem for analyzing the sampled water, a calibration subsystem for calibrating the ion chromatographic subsystem, and an automatic control subsystem for operating the monitoring system of the present invention.

Abstract: A liquid sample subject to inclusion of impurities is concentrated by a predetermined concentration factor selected by an operator, with the concentrated sample being thereafter provided to an analyzer so that a meaningful chemical analysis may be performed. A first pump delivers the sample to a liquid reservoir at a first rate and the liquid is boiled to provide a liquid-vapor mixture, with the liquid portion of the mixture being returned to the reservoir by means of a vapor separator. Another pump delivers the concentrated reservoir fluid to an analyzer at a second flowrate, with the ratio of the flowrate of the first pump to the second pump being equivalent to the desired concentration factor. In another embodiment, a faster response time is attained by first boiling the input sample and providing the liquid which is separated from the liquid-vapor mixture to a relatively small reservoir.

Abstract: A device for detecting the degree of contamination of a gas filter system by a contaminating gas. The device comprises a filter chamber having a pair of grids positioned therewithin and coated with a semiconductive polymer whole bulk conductivity changes due to a chemical reaction between the polymer and a contaminating gas. Measurement of the change is then utilized to indicate the degree of contamination in the filter system.

Abstract: A plurality of cuvettes joined together by breakable links between each cuvette for use in testing blood for its ABO classification and the presence of a typical antibodies, and for crossmatching blood for compatibility, together with label means for indicating the reagents used in each cuvette and the identity of the person whose blood is being tested. The cuvettes may be adapted to accept a closure means which permits the cuvettes to be pre-packaged with reagents required to carry out blood tests. The cuvettes have a hydrophilic polymer coating thereon that is non-destructive of red blood cells.

Abstract: Packing for fluidized bed reactors, is improved by providing alternately inclined baffles connected directly to each other or by means for connecting the said baffles into grids located in one or several levels, the said baffles forming expanding and contracting cells in the direction of the flow. The size, spacing in grids and the angle of attack of these baffles and spacing of grids are the same throughout the reactor volume when uniform distributions of the fluidizing agent and the fluidized medium are required. Alternatively, a device of this type is improved by providing variable sizes, spacing in grids, and angle of attack of these baffles and spacing of grids when specified nonuniform distributions of the flow of the fluidizing agent and the concentrations of the fluidized media are desired for particular applications.

Abstract: A process of leaching ores, ore concentrates, intermediate metallurgical products and the like, which contain acid-soluble constituents, by a treatment in an acid aqueous solution under pressure in a tubular reactor. The slurry contains suitably 300 to 1100 g starting material per liter of water and a velocity of flow of 0.5 to 4.0 m/sec. is suitably maintained throughout the flow path in the tubular reactor of the slurry and of the leached suspension.

Abstract: Vanadium values are recovered from sulphur-containing cokes and ashes derived from heavy oils by a novel process comprising heating in the presence of alkali metal carbonate, contacting the resulting solid residue with water to form a leach and recovering the vanadium values dissolved therein. The amount of alkali metal carbonate used is at least sufficient to convert the vanadium values present in the raw material into alkali metal vanadate, but insufficient to react in addition with all of the sulphur values therein. The heating step solubilizes only alkali metal vanadate and thus the leach solution is substantially free of contaminating substances.

Abstract: A starting solid mixture of AlCl.sub.3 and Nacl, which may have been obtained by acid leaching of an aluminiferous mineral and precipitation of the AlCl.sub.3 and NaCl, is mixed with water in an amount to form an aqueous solution containing NaCl and AlCl.sub.3 in a weight ratio Na.sub.2 O/Al.sub.2 O.sub.3 of about 0.028. This is sparged with HCl to precipitate AlCl.sub.3, but the sparging is stopped before a substantial concentration of NaCl starts to come out of solution. The precipitated AlCl.sub.3 may be calcined to Al.sub.2 O.sub.3 and washed to remove any residual NaCl.

Abstract: Crystalline 2-layer lithium aluminate, especially when carried in an ion exchange resin, is regenerated for use as an extractor for Li.sup.+ values in aqueous solution, said regeneration being done by using an aqueous wash containing at least about 800 ppm Li.sup.+ ion.

Abstract: Fuel gas produced in a coal distillation or gasification plant 1 is fed to a power plant 5 and chlorine, fluorine, sulphur and compounds thereof in the fuel gas are separated from the fuel gas, and also from flue or exhaust gas emanating from the power plant, in two stages. In a first stage, chlorine and fluorine and their compounds are separated, preferably in the dry using alkali metal or alkaline earth metal oxides, hydroxides or carbonates, in a separator 3. In a second stage sulphur and its compounds, together with further chlorine, fluorine and their compounds, if any, produced in the power plant, are removed from the flue or exhaust gas from the power plant in a desulphurizing plant 6. This two stage process is thermally more efficient and less costly than a process in which the chlorine, fluorine sulphur and their compounds are all removed at once from the fuel gas.

Abstract: A process for the removal of sulfur oxides from two gas streams containing the same. One gas stream is introduced into a spray dryer zone and contacted with a finely dispersed spray of an aqueous medium containing an absorbent for sulfur oxides. The aqueous medium is introduced at a controlled rate so as to provide water to the gas in an amount to produce a cooled product gas having a temperature at least 7.degree. C. above its adiabatic saturation temperature and from about 125-300% of the stoichiometric amount of absorbent required to react with the sulfur oxides to be removed from the gas stream. The effluent from the spray dryer zone comprises a gas stream of reduced sulfur oxide content and contains entrained dry particulate reaction products including unreacted absorbent. This gas stream is then introduced into a particulate removal zone from which is withdrawn a gas stream substantially free of particles and having a reduced sulfur oxide content.

Abstract: Dicalcium phosphate dihydrate composition having improved monofluorophosphate compatibility are prepared by the addition of magnesium oxide and pyrophosphoric acid to the reaction mixture, and terminating the reaction by which the dicalcium phosphate dihydrate is formed at a low pH.

Abstract: A method of synthesizing a crystalline aluminosilicate zeolite from a reaction mixture containing a base, silica, alumina and water, wherein an alkali metal compound and an amide compound are concurrently used as said base.

Abstract: An apparatus and process are disclosed for utilizing solar radiation and the energy contained therein for the carbothermic reduction of a metal oxide to a metal carbide. The apparatus comprises a reflective surface which collects and focuses solar radiation onto a focal mirror which consequentially reflects and focuses the solar light rays into a reaction chamber through a Fresnel lens and a transparent window provided on the chamber. The solar light rays are focused by the reflective surface focal mirror and Fresnel lens such that the energy absorbed by reactants in the reaction chamber is sufficient for the carbothermic reduction of the metal oxide.

Abstract: An economical process for treating the acidic pond water to be used in the internal grinding circuit of a wet process phosphoric acid plant. Water is added to a quantity of a hydratable calcium compound, such as quicklime, to form a slaked lime slurry. A sufficient quantity of the slaked lime slurry is reacted with the acidic pond water to obtain a low fluoride solution having a fluoride content less than about 300 ppm and a pH in the range from about 2.0 to about 3.0, preferentially in the range 2.6-2.8, whereby calcium fluoride is precipitated. The precipitate bearing low fluoride solution is then clarified and the precipitate removed as underflow from the clarifier and transferred to the gypsum pond. In the preferred embodiment, the clarified low fluoride water is fed to the ball mill and is mixed with the phosphate rock being crushed.

Abstract: Ferrite having a uniform degree of oxidation is produced at a higher rate of ferrite forming reaction by pelletizing a mixture of iron oxide and ferromanganese powders and calcining the mixture at a temperature of 900.degree. C. or higher. Zinc oxide, magnesium oxide and/or nickel oxide may be further added to the mixture, as required.

Abstract: Slaked lime (calcium hydroxide) is obtained by contacting quicklime (calcium oxide) with an aqueous solution containing at least one anion selected from the group consisting of Cl, Br and NO.sub.3 ions in a concentration of about 0.1 to about 5 mole/liter at a temperature of about 10.degree. C. to about 65.degree. C. Magnesium hydroxide can be produced by reacting the aforesaid slaked lime with magnesium chloride or magnesium nitrate in an aqueous medium, the amount of slaked lime being about 0.5 to about 0.95 equivalent per equivalent of the magnesium compound, and thereafter heat-trating the reaction product in an aqueous medium at a temperature of about 150.degree. C. to about 250.degree. C.

Abstract: Antibodies to human carcinoembryonic antigen (CEA), human alphafetoprotein (AFP) and/or to other anti-human tumor associated antigens (TAA) labeled with technetium-99m (Tc-99m) are administered to a human after the human has been administered anti-CEA, anti-AFP and/or other anti-TAAs, such as human melanoma-associated antigen, human neuroblastoma-associated antigen, human breast cancer-associated antigen, human ovary-associated antigen, human sarcoma-associated antigen, etc. The biodistribution of the labeled product composition accumulates at cancer sites, e.g., tumors that produce or express TAA, due to the affinity that the antibody has for the given tumor antigen. The accumulation at the tumor site(s) of a suitable amount of Tc-99m associated with the antibody allows detection via external scintigraphy and other means. Detection of the Tc-99m antibody composition by external scintigraphy permits localization and detection of tumors in vivo via a semi-noninvasive technique.

Abstract: There is disclosed a polymeric diffusion matrix for the sustained release of chlorpheniramine maleate by transdermal delivery to a patient wherein the matrix comprises a polar plasticizer, polyvinylalcohol, polyvinylpyrrolidone, and a pharmaceutically effective amount of chlorpheniramine maleate.

Abstract: Oral compositions such as toothpastes, mouthwashes, lozenges and chewing gum containing an antimicrobial agent which is effective against plaque/gingivitis and mouth odor are disclosed.

Abstract: An intramammary composition containing a siloxane elastomer with incorporated antibacterial agent. The composition is of sufficiently low viscosity to facilitate application to the teat of a cow via the streak canal, and the composition remains sufficiently elastic to enable it to remain in place during the dry period and to allow it to be readily milked-out at the onset of lactation. The composition is useful in reducing mammary infections in cattle during their dry period and is compatible with conventional mastitis treatments at the end of lactation.

Abstract: Hair conditioning compositions in the form of an emulsion comprising a volatile agent, a nonionic, water soluble thickening agent, a cationic hair conditioning agent and water.

Abstract: A phamaceutical insertion composition comprising a mixture of an aqueous solution of carboxyvinyl polymer with a water-soluble basic compound and a pharmaceutical ingredient, said mixture being a gel having a pH value of from 4 to 10 and a viscosity of from 5,000 to 100,000 centipoises at 20.degree. C., which composition is applied to the rectal, vaginal or urethral tissue and the pharmaceutical ingredient is absorbed into the blood stream of the human body.

Abstract: The method and composition of the invention comprises one or more synthetically prepared, substantially pure compounds effective as odor attractants to lure coyotes having the structure-- ##STR1## where R is hydrogen or methyl and R' is hydrogen, secondary butyl or alkyl containing 1 to 17 carbon atoms placed on a solid substrate in an amount sufficient to attract coyotes.

Abstract: A novel live vaccine for the prevention of salmonellosis in water fowl comprising essentially a suspension of living culture of the attenuated strain Salmonella typhi-murium No. 3, deposited at the All-Union State Research Control Institute for Veterinary Preparations, the USSR Ministry of Agriculture (No. 121), in a concentration of 2-4 billion microbe cells per 10 cm.sup.3 of drinking water. A process for making said vaccine, wherein the attenuated strain Salmonella typhi-murium No. 3 is cultivated in a culture medium containing sources of carbon, nitrogen, mineral salts, biologically active substances at a temperature of 37.degree.-38.degree. C. to produce the highest attainable accumulation of biomass during a period of 10-14 hours with subsequent drying and obtainment of the vaccine.

Abstract: Novel nitrosourea derivatives are provided which possess a high level of inhibitory activity against leukemia and tumors and which are therefore useful for pharmaceutical purposes. The compounds have the structure represented by formula (I): ##STR1## wherein R.sub.0 represents --OH or --OC.sub.m H.sub.2m+1 where m is an integer of 1 to 3 and one of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 represents ##STR2## where X is ##STR3## or an alkylene group of 1 to 3 carbon atoms, n is an integer of 1 to 3 and Y is the group on the .alpha.-carbon atom of an .alpha.-amino acid and each of the remaining three represents --OH; or wherein R.sub.0 represents ##STR4## and R.sub.1, R.sub.2, R.sub.3 and R.sub.4 each represent --OH; or by formula (II): ##STR5## wherein X and n have the same meanings as above; and p is an integer of 1 to 5.

Abstract: There are disclosed processes for preparing carboxyalkyl dipeptide derivatives and related compounds which are useful as angiotension converting enzyme (ACE) inhibitors and as antihypertensives and pharmaceutical compositions containing these carboxyalkyl dipeptide compounds in combination with another antihypertensive and/or diuretic compound.

Abstract: The present invention relates to an amino acid derivative represented by the formula ##STR1## wherein R.sub.1 and R.sub.2 represent hydroxyl, alkyloxy, aryloxy, arylkyloxy, alkyl, aryl, or aralkyl; R.sub.3, R.sub.5, R.sub.8 and R.sub.11 are hydrogen or alkyl; R.sub.4, R.sub.7 and R.sub.10 are hydrogen, or substituted or unsubstituted alkyl, aryl or aralkyl; R.sub.6 and R.sub.9 are hydrogen, alkyl, aryl, or aralkyl; R.sub.12 is hydroxyl, alkyloxy, aryloxy, aralkyloxy, amino, mono- or di-alkyl-, aryl- or aralkyl amino; and R.sub.6 and R.sub.7 combined together, and R.sub.9 and R.sub.10 combined together independently may form a substituted or unsubstituted alkylene bridge. The present invention also relates to a method of preparing said amino acid derivatives, and to anti-hypertensive drugs containing them.

Abstract: A novel method of treating prostate adenocarcinoma, prostate benign hypertrophia, endometriosis, dysmenorrhea, hirsuitism, hormono-dependent mammary tumors, treatment and prevention of precocious puberty, induction of a retardation of the appearance of puberty and treatment of acne of mammals comprising administering to warm-blooded animals an effective amount of a peptide of the formulap Glu--His--Trp--Ser--Tyr--X--Y--Arg--Pro--Z (I)wherein (a) Z is Gly--NH.sub.2, Y is Leu and X is Gly, (b) Z is Gly--NH.sub.2, Y is Leu, X is DN Leu, DN Val, D Abu (.alpha.-aminobutyric acid), D Phe, D Ser, D Thr, D Met, D Pgl, D Lys, Leu, Ile, Nle, Val, N Val, Met, Phe, D Leu, D Arg, D Ser (tbu), D Thr (tbu), D Cys (tbu), D Asp (O tbu), D Glu (Otbu), D Orn (boc), D Lys (boc), D Trp, Trp, 2-methyl Ala, D Tyr, D Met, .epsilon.-lauryl -D Lys, .epsilon.

Abstract: Novel peptide derivatives, inclusive of salts thereof, of the formula ##STR1## wherein A represents monocyclic or bicyclic hydrocarbon group, R.sup.1 and R.sup.3 are independently hydrogen, C.sub.1-4 alkyl or phenyl-C.sub.1-4 alkyl, and R.sup.2, R.sup.4 and R.sup.5 are independently hydrogen or C.sub.1-4 alkyl, have inhibitory activities of angiotensin converting enzyme and bradykinin decomposing enzyme, and are useful as antihypertensive agents.

Abstract: A pharmaceutical composition is disclosed which comprises the combination of interphenylene 9-thia-11-oxo-12-aza prostanoic acid derivatives and carboxyalkyl dipeptide derivatives.

Abstract: Novel pharmaceutical preparations of dissolved insulin having improved physical stability particularly adapted for use in continuous insulin delivery equipment prepared by incorporating therein a calcium or magnesium salt so as to provide a solution containing essentially ionized calcium or magnesium in insulin stabilizing concentrations.The magnesium or calcium ions concentrations are with the range of about 0.4.times.10.sup.-3 to 10.sup.-2 molar.

Abstract: 5-Fluoro-(.beta.-uridine or 2'-deoxy-.beta.-uridine) derivatives having an acyl group at the 3-position of the molecule. These compounds are useful as carcinostatic agent. This disclosure relates to such compounds, a process for producing the same and a carcinostatic agent comprising such a compound.

Abstract: A pharmaceutical composition suitable for increasing cerebral serotonin concentration, comprising a serotonin precursor selected from the group consisting of 5-hydroxytryptophan and derivatives of 5-hydroxytryptophan having the formula: ##STR1## wherein R represent hydrogen; a C.sub.1 -C.sub.12 alkyl group; or a C.sub.5 -C.sub.16 alicyclic, monocyclic aromatic hydrocarbyl, or polycyclic aromatic hydrocarbyl group; and a nitrogenous heterocyclic compound selected from the group consisting of inosine, theophylline, theobromine, allopurinol, pyridoxine, hypoxanthine, folic acid, adenine, nicotinamide, caffeine, and orotic acid.

Abstract: New semi-synthetic antibiotic derivative are formed from N-methanesulfonic acid derivatives of 3-O-demethylistamycin B which are less toxic than the parent 3-O-demethylistamycin B and retain usefully high antibacterial activity of the parent antibiotic. The new derivatives are produced by a method of N-sulfomethylation where 3-O-demethylistamycin B is reacted with an aldehyde such as paraformaldehyde and sulfurous acid or sulfite reagent.

Abstract: An organophosphorus compound of the formula ##STR1## where R and R.sup.1 together form a 1,3-butadien-1,4-diyl group optionally substituted with a chloro group, or R and R.sup.1 together form a 1,2-ethenediylthio group wherein sulfur is attached to carbon; R.sup.2 is hydrogen, chlorine or bromine; X is O or S; R.sup.3 is C.sub.1 -C.sub.2 alkyl; and R.sup.4 is C.sub.1 or C.sub.2 alkoxy or propylthio is disclosed. The organophosphorus compounds defined above are effective in the control of insects, nematodes and acarids.