Abstract: An SS-OCT apparatus includes a clock generator configured as an interferometer including an optical path through which part of light emitted from a light source passes, the optical path being split into a first optical path and a second optical path having an optical path length difference relative to the first optical path, to generate a clock used by a converter sampling an analog signal; a tomographic image obtaining unit configured to obtain a tomographic image of a fundus by using a digital signal converted from the analog signal sampled by the converter using the generated clock; and a scan unit configured to scan illumination light across the fundus at a scan angle of 47 degrees or more in air. The tomographic image obtaining unit is configured to obtain a tomographic image of the fundus at a distance of 4.0 mm more within an eyeball in a depth range.

Abstract: The innovation provides for a system and method available to image and visualize the palisades of Vogt via a non-contact process, analyze the image volumes acquired, evaluate the status of the palisades of Vogt from the data represented therein, and display the data in real-time or as a part of a medical record for ongoing consideration and evaluation.

Abstract: Postoperative lens position is predicted on the basis of known measured values, such as the corneal thickness, the depth of the anterior chamber, the eye length, and the distances of the capsular bag equator and/or of the lens haptic from the anterior surface of the lens. In addition, the calculation also takes into account the attitude of the intraocular lens, for which purpose additional parameters of the pseudophakic eye are used that have not previously been taken into consideration. The proposed method is suitable for a more exact prediction of the strength and nature of an intraocular lens to be implanted in a pseudophakic eye in the context of cataract surgery or of a refractive intervention. The method is based on the use of suitable calculation methods, e.g. geometric optical formulae, or of ray tracing.

Abstract: Some demonstrative embodiments include apparatuses, systems and/or methods of determining a pupillary distance. For example, a product may include one or more tangible computer-readable non-transitory storage media including computer-executable instructions operable to, when executed by at least one computer processor, enable the at least one computer processor to implement operations of measuring a pupillary distance between pupils of a user. The operations may include receiving a captured image comprising first and second reflections of a light of a light source, the first reflection comprising a reflection of the light from a first pupil of the user, and the second reflection comprising a reflection of the light from a second pupil of the user; and determining the pupillary distance based on locations of the first and second reflections in the captured image and an estimated distance between an image capturing device and pupils of the user, when the image is captured.

Abstract: There is provided an eyeball observation device, which can stably detect a line of sight, the eyeball observation device including: at least one infrared light source configured to radiate polarized infrared light onto an eyeball of a user; and at least one imaging device configured to capture an image of the eyeball irradiated with the polarized infrared light and to be capable of simultaneously capturing a polarization image with at least three directions.

Abstract: A fundus imaging system includes: an image sensor array, where the image sensor array includes monochrome photodiodes and global shutter control, an illumination unit with one or more light-emitting diodes that have one or more dies, a computing system including a processor and memory, one or more lenses, one or more reflective mirrors, and a display. In an example method of use, a clinician positions a patient, initiates a focal adjustment, initiates a retinal imaging process, and the same or a different clinician views the image. In some embodiments, the imaging system is configured to analyze the image and identify detected physical attributes in the image relating to the diagnosis and treatment of diabetic retinopathy.

Abstract: A contact lens is placed on a patient's eye during ophthalmic surgery, such as vitreoretinal surgery. The contact lens rests on a cornea of an eye of a patient during the surgery and is supported by a contact lens mounting speculum having multiple degrees of freedom to accommodate small movements of the eye while enabling alignment to an optical axis of the surgical microscope. The contact lens mounting speculum may be used with different patients, speculum blades, contact lenses (direct and indirect), and lens mounting positions.

Abstract: A system for visualization of eye anatomy includes at least one camera having a view vector along a first axis when in a first position, a housing to which the camera is coupled, wherein the housing engages the head of a patient such that the camera is positioned adjacent a patient's eye, and an actuator that moves the camera from the first position to a second position with a view vector along a second axis that is offset from the first axis. A method of visualization of eye anatomy includes engaging a patient's head with a housing, positioning at least one camera coupled to the housing adjacent an eye, wherein the camera has a view vector along a first axis when in a first position, and moving the camera to a second position with a view vector along a second axis offset from the first axis.

Abstract: A measurement system may comprise a sensor wire and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body and two sensors disposed within the insertable portion at a distal end of the sensor wire. The sensors are configured to measure a parameter when inserted inside the patient. The transceiver unit may comprise: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module.

Abstract: An apparatus for controlling communication with an attachable sensor attached to a target patient includes a circuit. The circuit obtains a first piece of battery data indicating a state of a first battery included in the sensor, the first piece of battery data being transmitted from the sensor to the apparatus through a network. The circuit issues, to the sensor, a communication control command that changes a communication setting set in the sensor to a setting according to the first piece of battery data.

Abstract: An apparatus for detecting a biological data of a target patient from an attachable sensor attached to the target patient includes a circuit. The circuit obtains a first piece of biological data of the target patient and second piece of biological data of the target patient that is a different type of biological data than the first piece of biological data. The first piece of biological data and the second piece of biological data is collected by the sensor. The circuit standardizes the first piece of biological data on the basis of the second piece of biological data so as to generate standardized biological data.

Abstract: The current invention has provided a method for detecting, in a noninvasive in-vivo manner, UV-induced skin damage and a detection device thereof. After irradiated by ultraviolet light, the autofluorescence is generated at the wavelength ranging from 490 nm to 640 nm under the skin, following the excitement of laser having a wavelength ranging from 440 nm to 510 nm, wherein the changes of the autofluorescence intensity at the wavelength of 490-640 nm is positively correlated with the skin damages.

Abstract: The present invention provides imaging devices, systems, and methods of operation for acoustic-enhanced optical coherence tomography. The systems coordinate imaging devices, optical coherence tomography (OCT), and pulsed ultrasound (FUS) and or pulsed ultrasound (PUS) to enhance the contrast of images. Moreover, the systems improve in vivo diagnosis and drug release through the utilization of sonographic enhancers such as microbubbles (MBs).

Abstract: An apparatus for skin imaging is provided. The apparatus is used in conjunction with a mobile device to obtain digital images using a digital camera and a light source provided by the mobile device. The apparatus includes an optical system for illuminating an object to be imaged with uniform ambient light and a light conduit for delivering reflected light to the mobile device digital camera. The apparatus is removably attachable to the mobile device and/or a mobile device case. One or more optical elements, such as lenses, films, filters, and light caps may be used to improve image quality and/or acquire magnified images.

Abstract: Methods and systems are provided for the detecting and presenting of faint signals from a real-time interactive imager. A real-time view of a subject is controlled by a user by entering commands that move the subject or a camera used to record the real-time view. The rate of this movement is monitored, and when the rate descends below a preset value, a trigger is sent to the camera. In response to the trigger, the camera switches to a lower frame frequency for capturing the real-time view of the subject, thereby increasing the amount of light collected in each frame, and increasing the sensitivity of the camera to faint signals. The methods and systems are particularly relevant for surgical or biopsy imaging, in which both a higher frame rate preview image of a subject for 3D visualization, and a higher sensitivity fluorescence image of the subject for tumor margin assessment, are desired.

Abstract: A wearable device includes a measurement device having light emitting diodes (LEDs) measuring a physiological parameter. The measurement device modulates the LEDs to generate an optical beam having a near-infrared wavelength between 700-2500 nanometers. Lenses receive and deliver the optical beam to tissue, which reflects the optical beam to a receiver having spatially separated detectors coupled to analog-to-digital converters configured to generate receiver outputs. The receiver captures light while the LEDs are off, and reflected light from the tissue while the LEDs are on, to generate first and second signals, respectively. Signal-to-noise ratio is improved by differencing the first and second signals and by differencing the receiver outputs. The measurement device further improves signal-to-noise ratio of the reflected optical beam by increasing light intensity of the LEDs relative to an initial light intensity.

Abstract: The objective of the invention is to make it possible to provide a high-resolution photoacoustic imaging device at low cost. This photoacoustic wave detecting device includes: a beam splitter (111) which splits emitted light from a light source; an optical physical property shifting unit (120) which changes at least one physical property of the split lights in such a way that the split lights interfere with each other; a lens (140) into which each split lights enters parallel to the optical axis; and an acoustic detecting unit (150) which detects an acoustic wave generated in a region of an observation target at the focal point of the lens (140).

Abstract: A probe array in which probes are arranged on a cup-shaped acoustic wave detector at high density. In the probe array, transducers (acoustic wave conversion elements) configured to be capable of conversion between acoustic waves and an electrical signal are provided on a support member (housing).

Abstract: Support structures for positioning sensors on a physiologic tunnel for measuring physical, chemical and biological parameters of the body and to produce an action according to the measured value of the parameters. The support structure includes a sensor fitted on the support structures using a special geometry for acquiring continuous and undisturbed data on the physiology of the body. Signals are transmitted to a remote station by wireless transmission such as by electromagnetic waves, radio waves, infrared, sound, and the like or by being reported locally by audio or visual transmission. The physical and chemical parameters include brain function, metabolic function, hydrodynamic function, hydration status, levels of chemical compounds in the blood, and the like. The support structure includes patches, clips, eyeglasses, head mounted gear and the like, containing passive or active sensors positioned at the end of the tunnel with sensing systems positioned on and accessing a physiologic tunnel.

Abstract: A apparatus for detecting a biological data of a target patient from an attachable sensor attached to the target patient includes a circuit. The circuit obtains the biological data and sensor-state data of the sensor, the biological data and the sensor-state data being collected by the sensor. Further, the circuit evaluates the reliability of the biological data on the basis of a comparison between the sensor-state data and an operation permitting condition for the sensor that is a condition under which a normal operation of the sensor is ensured.

Abstract: Systems, methods, and an event detection apparatus, for the detection of an imminent adverse physiological event, such as an epileptic seizure or cardiac event. Physiological state data can be generated based on at least one of pre-processed physiological state data, electrocardiogram (ECG) signals, and motion sensor signals. A plurality of features from the physiological state data can be extracted. The plurality of features can be classified based on a predetermined classifier. Responsive to the plurality of features corresponding to at least one of a plurality of adverse physiological event profiles, an adverse physiological event can be determined to be imminent.

Abstract: An electronic device and a method are provided. The electronic device can include a motion sensor, a heart rate monitor sensor, and a processor functionally coupled with the motion sensor and the heart rate monitor sensor. The processor can be configured to obtain first motion sensor data for a first duration using the motion sensor, obtain first heartbeat data for the first duration using the heart rate monitor sensor, determine an exercise type based on the first motion sensor data, determine a heartbeat prediction range based on at least one of the first motion sensor data, the exercise type, and the first heartbeat data, obtain second heartbeat data for a second duration using the heart rate monitor sensor, determine whether the second heartbeat data falls within the heartbeat prediction range, and determine heartbeat data of the second duration based on the determination result.

Abstract: An information processing system includes first and second electrodes for measuring cardiac potential, a pulse wave sensor that is disposed closer to the first electrode than to the second electrode and that measures a pulse wave, a buffer that amplifies a signal acquired by the first electrode, an interconnect wire that electrically connects the first electrode to a terminal of the buffer, a shield that shields the first electrode and the interconnect wire, and a shield potential generator that includes a first buffer circuit and a second buffer circuit having a larger drive current than the first buffer circuit and that starts applying, to the shield, a first generation signal generated by the first buffer circuit based on the acquired signal before a predetermined time point when the pulse wave is measured and starts applying a second generation signal generated by the second buffer circuit at the predetermined time point.

Abstract: A medical implant for intravascular implantation has an implant housing and at least a first and a second conveying element. The first and the second conveying elements are arranged on the implant housing in one plane. The first conveying element is mounted rotatably about a first rotation axis and the second conveying element is mounted rotatably about a second rotation axis.

Abstract: An artificial electronic skin according to the present disclosure comprises: a lower electrode; a first layer laminated on the lower electrode; a first micro dome formed on the first layer in a semispherical shape so as to stand upright upwards; a second layer laminated on the first layer; a second micro dome formed on the lower portion of the second layer, which lies opposite the first layer, in a semispherical shape to be able to engage with the first micro dome; an upper electrode laminated on the upper end surface of the second layer; and a pattern layer laminated on the upper end surface of the upper electrode so as to receive an external pressure applied thereto. The artificial electronic skin according to the present disclosure is advantageous in that a dynamic pressure, a static pressure, and a temperature can be sensed and distinguished by a single element, using different signals.

Abstract: A monitoring device wearable by a person to be monitored, comprising: one or more sensing means for sensing cardio, respiratory, physiological and/or other information from the person; processing means for analysing the sensed information; memory means for storing the sensed and/or analysed information; and communication means for transmitting at least the analysed information. At least one waveform acquired from the sensed cardio, respiratory, physiological and/or other information is digitised in real time; analysis of the sensed and/or digitised information is performed in real-time and a welfare indication of the person computed in real-time; and the computed welfare indication of the person is transmitted by the communication means and/or stored in the memory means.

Abstract: A blood pressure meter includes a pump and a first fluid path provided inside a main body. The first fluid path feeds a fluid from the pump to a fluid bladder or discharges the fluid from the fluid bladder. A pressure sensor is mounted on a first substrate disposed inside the main body. A second fluid path that introduces the fluid from the fluid bladder to the pressure sensor is provided. The second fluid path includes an inlet pipe that is integrally formed with a sensor package that incorporates the pressure sensor, and extends straight between the fluid bladder and the pressure sensor. A second substrate on which a blood pressure measurement element is mounted is disposed in a space that is located between the first substrate and the fluid bladder in a thickness direction and is adjacent to the second fluid path in a planar direction.

Abstract: A sensor system comprises first and second PPG sensors. A monitoring system monitors detection by at least one of the first and second detectors an optical calibration signals, for performing time calibration between the first and second PPG sensors. This system makes use of two PPG sensors. To enable these sensors to be independent units, rather than being fully integrated into a combined system, a calibration system is provided. Based on detected optical signals, the behavior over time of each PPG sensor can be monitored and thus calibration can take place.

Abstract: A workout information display method includes: acquiring workout information based on a workout executed by a user; displaying a graph in which a first axis represents a distance or a time and a second axis represents a measurement value of each measurement item of the workout information in a first display region; displaying first to P-th icons for selecting setting of measurement values of first to P-th measurement items on the second axis of the graph in a second display region; and displaying a measurement value of the measurement item corresponding to the icon in regard to at least one of the first to P-th icons.

Abstract: A method for characterizing an electrocardiogram, including receiving a first unipolar signal from a first location of a heart and a second unipolar signal from a second location of the heart. The method further includes generating a bipolar signal from the first and second unipolar signals, and analyzing the bipolar signal to delineate a time period during which the first and second locations generate a bipolar complex. The method also includes analyzing the first unipolar signal within the time period to determine an activation time of the first location.

Abstract: The present invention relates generally to a method for preventing gravity-induced loss of consciousness (G-LOC), which arises from increased acceleration during flight, and more particularly, to a G-LOC warning method and system using a G-LOC warning algorithm, which detects, in advance, risk factors that cause a G-LOC state by monitoring a change in the electromyogram (EMG) signal in real time. According to the G-LOC warning method and system using the G-LOC warning algorithm of the present invention, because information about the EMG signal is measured and collected in real time, changes in the EMG signal of a pilot who is exposed to high levels of acceleration during a flight maneuver are measured and checked on the spot.

Abstract: The invention discloses a system for measuring electromyographic signals of deep muscles based on sEMG, comprising: a measuring electrode, an EMG signal collector and a data processing device; wherein the measuring electrode is a monopolar needle electrode or a fine-wire electrode, the EMG signal collector is connected to the measuring electrode to collect the measured EMG signals therefrom; and the data processing device is connected to the EMG signal collector for acquiring parameters corresponding to sEMG on the basis of the collected EMG signals. According to embodiments of the present invention, the electromyographic activity of a single targeted muscle and a deep muscle can be detected by replacing existing surface electrodes with monopolar needle electrodes or fine-wire electrodes, and thereby limitations that surface electrode recordings are restricted to superficial muscle groups underneath the electrodes can be eliminated.

Abstract: A biological information measuring apparatus includes a radiation emitting unit configured to emit radiation to a subject, a biomagnetic field detector configured to detect a biomagnetic field on the subject, and a radiation sensitive material having sensitivity to the radiation, having enough size for enabling radiography of an examination target of the subject, and being nonmagnetic. The radiation sensitive material is arranged between an examination region where the examination target of the subject is to be positioned and the biomagnetic field detector.

Abstract: In various embodiments, the present invention teaches methods and related systems for imaging the coronary arteries in high spatiotemporal resolution for the assessment of coronary stenosis. In some embodiments, the method teaches the use of a 3D radial k-space trajectory, continuous acquisition, retrospective cardiac and respiratory self-gating, and non-rigid cardiac and respiratory motion correction to reconstruct any arbitrary cardiac phase with minimal motion artifacts and high image quality.

Abstract: An exemplary system, method and computer-accessible medium for determining an arterial input function (AIF) of a mammal(s) can be provided, which can include, for example, receiving information related to a global circulatory system of the mammal(s), and determining the AIF based on the information by modeling a blood flow in the global circulatory system of the mammal(s) in terms of an input response function(s). The input response function(s) can include a delayed input response function(s). In certain exemplary embodiments of the present disclosure, the input response function(s) can include at least three input response functions, and each of the input response functions can be from a different part of a body of the mammal(s). The AIF can be determined by coupling the input response functions. The AIF can be further determined based on a total tracer amount in an organ(s) of the mammal(s).

Abstract: A method is proposed for recording diagnostic measurement data of a head of an examination object in head imaging via a magnetic resonance device. The method comprises performing an overview scan of the head of the examination object, wherein overview measurement data is acquired in the overview scan and performing various diagnostic scans of the head of the examination object based on the acquired overview measurement data, wherein diagnostic measurement data is acquired in the various diagnostic scans.

Abstract: The present disclosure relates to a system and method for non-invasively determining NAFLD activity scores (NAS) in patients using mechanical properties determined through magnetic resonance elastography (MRE) imaging. The non-invasively determined NAS score is then used to diagnose NFALD and NASH patients.

Abstract: Provided herein is a skin resistance measuring device having a simple structure and capable of accurately measuring a skin resistance. An AC voltage generated by a high-frequency power source (21) is applied to a first electrode (11). A detection circuit (30) detects a current of a second electrode (12). An inductive element (25) is provided, for example, in an electric path extending from the high-frequency power source (21) to the first electrode (11). A controller (40) changes and controls a frequency of the high-frequency power source (21), receives a detection signal (S1) from the detection circuit (30), and calculates an impedance of the human body which has touched an electrode section (10). The skin resistance of the human body is calculated based on a value of impedance at a frequency where the impedance is a minimum.

Abstract: Fiducial localization methods and apparatus are described.

Abstract: Localization array position determination in a treatment room coordinate system is described. A method may include imaging, using an imaging system, a position of one or more markers integrated with a localization array in a treatment room and transforming the position of the one or more markers to a treatment room coordinate system. The method also includes determining the position of the localization array in the treatment room coordinate system based on the transforming.

Abstract: A calibration apparatus is provided for calibrating a medical tool having a tool tracking marker. The medical tool and the calibration apparatus are for use with a medical navigation system. The calibration apparatus comprises a frame, a frame tracking marker attached to the frame, and a reference point formed on the frame. The reference point provides a known spatial reference point relative to the frame tracking marker.

Abstract: A tissue marker delivery device includes a hollow cannula and a fibrous marker. The hollow cannula has a distal region. The fibrous marker is disposed within the distal region. The fibrous marker includes a plurality of bioabsorbable strands, and a binding agent. Optionally, the tissue marker delivery device may include a short-term marker that includes an imagable agent that does not interfere with imaging adjacent tissue.

Abstract: Disclosed embodiments describe techniques for body part analysis. Data is collected from a body sensor. The body sensor is coupled to a fabric attached to a body part. The body sensor provides electrical information based on a deformation of the body part. The data from the body sensor is analyzed to determine the deformation of the body part. An angle for the body part is determined based on the deformation. The data is augmented with additional data collected from an inertial measurement unit. Anchor points for the body part are determined, where the anchor points enable placement of the body sensor coupled to the fabric. The body part is treated, wherein the body part treatment is based on the analyzing. Additional data is collected from a second body sensor. The second body sensor is also coupled to the fabric.

Abstract: Embodiments disclosed herein provide methods, apparatus and computer systems comprising an input unit for inputting one or more data sets to be processed comprising a capacitance measuring device configured to measure one or more conductive elements on a sensor plane and provide a corresponding data set of measurements obtained from the conductive elements. A computing unit is coupled to the input unit and for processing the data sets; the computing unit comprises at least one processor with non-transient memory. An output unit is connected to the computing unit for outputting data received from the computing unit. A computer program stored in memory comprising instructions that cause the computer to isolate and discharge conductive and reference impedance elements, perform a charge transfer to the one or more conductive elements on the sensor plane, measure the relative difference between the conductive elements and reference impedance element, and store measurements in non-transient memory.

Abstract: In various embodiments, the present disclosure pertains to methods for measuring a size of a body lumen. A method may comprise: (a) inserting a balloon comprising a circumference, a proximal end, and a distal end into the body lumen, wherein the balloon is at least partially compliant; (b) introducing an inflation fluid into the balloon inside the body lumen until a point in time where the circumference of the balloon engages an inner wall of the body lumen; (c) measuring an amount of the inflation fluid introduced into the balloon; and (d) determining the size of the body lumen based at least in part upon a total amount of inflation fluid introduced into the balloon at a point in time. In various embodiments, the present disclosure pertains to apparatuses for measuring an inner diameter of a body lumen.

Abstract: The claimed invention comprises software methods for user continuity and physiological state change assessments through generating biometric profiles of individuals and/or groups of individuals by using physiological input together with biomathematical modeling and machine learning techniques. Intra-individual variation in physiological variables including, but not limited to: heart rate, heart rate variability, pulse waveform and its derivatives, blood pressure, breathing rate, cardiopulmonary coupling, actigraphy and circadian rhythms characteristics, are exploited.

Abstract: A method of measuring patient position by a patient monitoring system includes providing a first position sensor attachable to a portion of the patient, and providing a hub device that includes a calibration position sensor. A first calibration position measurement is received from the calibration position sensor while the hub device is aligned with the portion of the patient where the first position sensor is attached. A first patient position measurement is received from the first position sensor, and then a calibration map is determined for the first position sensor based on a difference between the first calibration position measurement and the first patient position measurement. Position measurement data is then received from the first position sensor, and a patient position is determined based on the position measurement data and the calibration map.

Abstract: Provided is a motion detection system capable of alleviating a burden on a caregiver which could arise when a plurality of types of notification target motions is detected during a short time period. A motion detection system (300) includes: an acquisition unit (52) for acquiring motion data indicating a motion of a person; a detection unit (150) for detecting a predetermined motion of the person using the motion data; a selection unit (160) for, when a plurality of types of output candidate motions is detected by the detection unit (150) during a predetermined time period, selecting an output target motion from among the output candidate motions such that types of the output candidate motions are made fewer than the plurality of types; and an output unit (170) for outputting the output target motion selected by the selection unit (160).

Abstract: An apparatus for detecting a biological data of a target patient from an attachable sensor attached to the target patient includes a circuit. The circuit obtains a first piece of biological data and patient-state data of the target patient. The circuit determine an activity state of the target patient on the basis of the patient-state data. When the activity state is first state, the circuit detects an abnormality in the target patient on the basis of a first normal value range, in the first state, of a physiological indicator indicated by the first piece of biological data and the first piece of biological data. When the activity state is second state, the circuit detects an abnormality on the basis of a second normal value range, in the second state, of the physiological indicator indicated by the first piece of biological data and the first piece of biological data.

Abstract: A data processing method for determining a range of motion of an artificial knee joint which connects a femur and a tibia via a medial ligament and a lateral ligament, wherein at least the femur comprises an implant which forms a medial condyle and a lateral condyle, the method comprising the steps of: acquiring the maximum lengths of the lateral ligament and the medial ligament for a particular flexion angle of the knee joint; calculating a first virtual position between the femur and the tibia in which the lateral condyle of the femoral implant touches the tibia and the medial ligament is stretched to its maximum length; calculating a maximum valgus angle of the range of motion from the first virtual position; calculating a second virtual position between the femur and the tibia in which the medial condyle of the femoral implant touches the tibia and the lateral ligament is stretched to its maximum length; and calculating a maximum varus angle of the range of motion from the second virtual position.