Abstract: A therapy utilizing inhaled anesthetic agents (such as desflurane, sevoflurane, isoflurane, or xenon) for the sedation of patients outside of the immediate perioperative space such as in the medical intensive care unit (MICU) and the surgical intensive care unit (SICU). The therapy includes controlled delivery of volatile anesthetic agents to patients undergoing ventilatory support on an ICU ventilator over extended periods of time. A system which provides for the delivery of anesthetic agents includes an anesthetic agent vaporizer element, an anesthetic agent reflector, and a plug-in cassette which contains both a cartridge housing liquid phase volatile anesthetic agent and an anesthetic vapor scrubbing medium.

Abstract: An inhalation therapy device includes a supply element for a gaseous medium, for example ventilation air of a ventilation device, and a flow influencing element, by means of which a sheath flow is formed around an expansion area for an aerosol generated by an aerosol generator for therapeutic administration. Deposition of aerosol droplets or particles on the inner way of the housing of the inhalation therapy device is effectively prevented in this manner.

Abstract: An apparatus and system for transferring a liquid, such as an anesthetic, from a reservoir to a machine while effectively minimizing the release of the liquid to the surrounding environment. The apparatus can include a first and a second component wherein twisting the first component and second component relative to each other causes a protrusion to seal or unseal a through-hole thereby allowing or preventing the flow of fluid and wherein a portion of an exterior surface of the second component that mates with a vaporizer has a polygonal shape with three or more flat sides.

Abstract: An apparatus and system for transferring a liquid, such as a liquid anesthetic, from a reservoir to a machine while minimizing the release of the liquid to the surrounding environment. The apparatus can include a first component having a through-hole, and a second component having an aperture, a support member extending into the aperture having a protrusion configured to be capable of sealing the through-hole, wherein a fluid in the reservoir may exit the reservoir by way of the through-hole and the aperture, wherein twisting the first component and second component relative to each other causes the protrusion to seal or unseal the through-hole thereby allowing or preventing the flow of fluid. A portion of the exterior surface of the second component can have a polygonal shape.

Abstract: An apparatus and system for transferring a liquid, such as a liquid anesthetic, from a reservoir to a machine while minimizing the release of the liquid to the surrounding environment. The apparatus can include a first component having a through-hole, and a second component having an aperture, a support member extending into the aperture having a protrusion configured to be capable of sealing the through-hole, wherein a fluid in the reservoir may exit the reservoir by way of the through-hole and the aperture, wherein twisting the first component and second component relative to each other causes the protrusion to seal or unseal the through-hole thereby allowing or preventing the flow of fluid. A portion of the exterior surface of the second component can have a cylindrical shape.

Abstract: An apparatus and system for transferring a liquid, such as an anesthetic, from a reservoir to a machine while effectively minimizing the release of the liquid to the surrounding environment. The apparatus can include a first and a second component wherein twisting the first component and second component relative to each other causes a protrusion to seal or unseal a through-hole thereby allowing or preventing the flow of fluid and wherein at least a portion of an exterior surface of the second component is cylindrically shaped for insertion into a vaporizer.

Abstract: An anesthetic vaporizer and a temperature compensation unit are disclosed. The temperature compensation unit, which cooperates with a vaporizing chamber having a bottom wall, includes a first device connected to the bottom wall of the vaporizing chamber for contacting with liquid anesthetic agent in the vaporizing chamber and changing in length according to temperature change of the liquid anesthetic agent, and a second device connected to the vaporizing chamber. A gas flow gap through which a gas flow passes is formed between the first and second devices. The gas flow gap becomes larger as temperature of the liquid anesthetic agent rises and smaller as the temperature of the liquid anesthetic agent drops.

Abstract: The present invention relates to an evaporator device to assist breathing comprising a low profile body adapted to house heating means (9), a liquid reservoir (8), an evaporation site and means (15) to supply liquid from the reservoir to the evaporation site such that the device can humidify the air in the immediate environment. The heating means may comprise PCMs, means to connect to external power, a heating mat and/or encapsulated materials which generate heat through an exothermic chemical reaction. The liquid may be water or a solution including or consisting of an active agent, for example a decongestant. The device may be used to produce nitric oxide to assist breathing.

Abstract: An apparatus for delivering water vapor to a gas is formed from a plurality of hollow fiber membranes each defining a passage for the flow of gas from an upstream end of the passage and enclosed by an enclosure. The hollow fiber membranes have a combined surface area in the range of about 90 square centimeters to about 110 square centimeters. The enclosure contains an air inlet positioned to direct air to the upstream end of each of the passages of the hollow fiber membranes and an air outlet positioned to direct air from the downstream end of each of the passages of the hollow fiber membranes. The enclosure preferably has a water inlet positioned to direct water toward the outer surfaces of the hollow fiber membranes and a water outlet positioned to direct water from the enclosure.

Abstract: An improved, pumpless respirator (ventilator) humidifier is provided with a water refilling device (1, 2) and with an electrically heated evaporator (5). The evaporator (5) has a tubular housing, which is filled with a porous sintered material. A front side of the housing is in liquid connection with the automatic water refilling device (1, 2) and the other front side is in connection with an evaporator chamber (4), through which breathing gas flows. The evaporator (5) is provided with a porous sintered glass or ceramic with a pore size of 10 ?m to 40 ?m in a first, lower, unheated area (14), and the evaporator (5) is provided with a porous sintered metal with a mean pore size of 50 ?m to 200 ?m in a second, upper area (15) heated by means of a heater (6).

Abstract: A disposable active humidifier for the mechanical ventilation of a patient, which has the particularity that it comprises a cartridge which forms a humidification chamber which is delimited by an inlet and by an outlet and can be interposed in the ventilation circuit. The cartridge has an interspace which is externally delimited by a heat exchange surface and is internally delimited by a hydrophobic membrane which surrounds the humidification chamber. A humidification fluid, originating from a bottle or bag, can be introduced in the interspace.

Abstract: An apparatus for providing humidification in a breathing assistance system may include a first container at least partially defining a first volume for housing an absorbent material, a second container at least partially defining a second volume for holding a liquid, and one or more fluid passageways for communicating the liquid from the second volume to the absorbent material in the first volume.

Abstract: Various systems, devices, NO2 absorbents, NO2 scavengers and NO2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.

Abstract: A device is provided for increasing humidity for respirating patients, especially for a respiration humidifier or an anesthesia reflector. The device includes a gas channel for passing through breathing air, a control and/or regulating device, a temperature sensor and a dew sensor for measuring the humidity present in the breathing air by electromagnetic radiation with a generating device and with a detection device for electromagnetic radiation. The humidity of the breathing air is determined at a low cost and in a reliable manner and condensation is avoided in the respiration system without any additional effort for sterilization. Humidity in the breathing air is determined by the a dew sensor by the change in the reflection of the electromagnetic radiation as a function of dew formation at a condensation-fogged and condensation-free boundary surface between breathing air and a medium having an optical density higher than that of breathing air.

Abstract: A CPAP device includes a humidifier including humidifier tub having a heat conducting base plate; and a cradle to support the humidifier tub in an operative position. The cradle may also support a flow generator in operative relation to the humidifier tub. The cradle includes a heater plate in communication with the heat conducting base plate of the humidifier tub in use. The cradle further includes a retaining mechanism to retain the humidifier tub in the cradle, the retaining mechanism being structured to force the base plate into engagement with the heater plate. The humidifier and/or flow generator may include various features to manage inadvertent back-spill of water from the humidifier to the flow generator.

Abstract: A conduit for a breathing circuit includes a heater associated, at least in part, with a portion of hydrophilic material. The purpose of the heater is to evaporate any condensed liquid collecting in the conduit, which is first sucked up by the hydrophilic material. The heated wick reduces the risk of collected water being passed to the patient and causing choking fits or discomfit. It is preferred that the heated wick lies freely in the conduit to settle at low points in the conduit where condensation may collect.

Abstract: An apparatus is disclosed for practicing a method of treating viruses in the nasal mucosa. Vapor is generated, heated and delivered to the nasal mucosa in intermittent bursts, timed to coincide with inhalation. Control circuits are provided to maintain the temperature of the vapor at the point of delivery at a level greater than that necessary to kill viruses in the nasal mucosa. Timing circuits can synchronize the vapor delivery with a breathing cycle with heated vapor being supplied during inhalation and blocked during exhalation. Other circuits terminate operation when liquid is insufficient or after a predetermined timed interval.

Abstract: A heat and moisture exchanger (HME) adaptor for a closed suction catheter assembly having one end in communication with a closed suction catheter assembly and another end configured to rotationally engage and releasably hold the HME is disclosed herein. The adaptor may include a retainer having an aperture that engages projections on the HME to releasably secure the adaptor to the HME. The adaptor may include a retaining ring that may be deformed or rotated to engage or disengage projections on the HME. The adaptor may be used with extended use closed suction catheter assemblies.

Abstract: The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug at a rate greater than 1000° C./s, thereby forming an vapor; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10 ? thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy.

Abstract: Xe exhaled from a patient is recovered with a polymeric membrane.

Abstract: A method including: providing a device that includes multiple tilted heating elements, and a housing that includes a fluid reservoir inlet that is adapted to receive an inverted fluid reservoir, a gas inlet that is adapted to receive pressurized gas from a gas pipe, a gas-vapor outlet; and activating the device to provide a controller mixture of gas and fluid. A device including: multiple tilted heating elements, and a housing that includes a fluid reservoir inlet that is adapted to receive an inverted fluid reservoir, a gas inlet that is adapted to receive pressurized gas from a gas pipe, a gas-vapor outlet; wherein the multiple tilted elements are placed at least partially within fluid within the housing and are adapted to heat the fluid such as to generate vapors; wherein the device is adapted to output, via the gas vapor outlet a mixture of gas and vapor.

Abstract: The invention concerns an apparatus for supplying a respiratory gas and a method of controlling the apparatus. In accordance with the invention there is provided an apparatus for supplying a respiratory gas comprising a conveyor device for conveying the respiratory gas, a conduit means for feeding the respiratory gas conveyed by the conveyor device to a person, and a humidification device for humidifying the respiratory gas, which is distinguished by a sensor device for generating a signal indicative in respect of the respiratory gas humidity and a control device for controlling the humidification device having regard to the signal which is generated by the sensor device and which is indicative in respect of the respiratory gas humidity.

Abstract: A liquid aerosol formulation comprising at least one thermally stable active ingredient selected from the group consisting of buspirone, buprenorphine, triazolam, cyclobenzaprine, zolpidem, pharmaceutically acceptable salts and esters thereof and derivatives thereof. The liquid formulation can include an organic solvent such as propylene glycol and one or more optional excipients. The active ingredient can be present in an amount of 0.01 to 5 wt. % and the formulation can be heated to provide a vapor which forms an aerosol having a mass median aerodynamic diameter of less than 3 ?m.

Abstract: An embodiment in accordance with the present invention provides a water dissipation device to remove water vapor from a humidified gas traveling through a breathing circuit between a patient and a ventilator, or a ventilator and a patient. The present invention includes a water dissipation device having a housing defining entry and exit ports for coupling to the breathing circuit and a breathable medium permeable to water vapor and impermeable to liquid water bacteria, viruses and other gases enclosed within said housing.

Abstract: A vaporizer apparatus for vaporizing medical herbs and essences is described that uses an electrical power driven medium to vaporize the herbs and essences. The vaporizer apparatus has a heating element assembly disposed within a shield. The shield is disposed within an opening of an enclosure. The shield protrudes from the opening at an angle and has a mating section for mating with a hand piece. The hand piece includes a vaporization chamber where herbs are packed, an inlet for connecting with the mating section of the shield, and an outlet for inhalation by a user. Methods for using the vaporizer apparatus is also discussed.

Abstract: A method and apparatus for delivering breathable gas to a user includes a humidifying unit that is controllable to humidify the gas in accordance with a variable humidity profile such that the gas is delivered to the user at variable humidity levels, e.g., during a treatment session.

Abstract: The systems disclosed herein relate to medical nebulizer systems, and more specifically interactive nebulizer compressors. In one embodiment an interactive nebulizer compressor includes an air compressor configured to output a pressurized gas. The embodiment further includes an enclosure surrounding the air compressor and a tubing coupler coupled to the enclosure. The tubing coupler can be further coupled to the air compressor and configured to cause the pressurized gas to be output from the enclosure. Lastly, the embodiment can include an interactive surface coupled to the enclosure.

Abstract: A method of detecting a level of anesthetic agent in an anesthesia vaporizer is disclosed. The anesthetic agent forms a column of liquid within an external indicator; the method projects a beam of light into the external indicator. The method further receives the beam of light after the beam of light has traveled through the column of liquid, and detects when the level of anesthetic agent drops below a predetermined level.

Abstract: A respiration moistener (1) has an inlet (3), into which incoming gas (2) to be moistened can be fed. Vapor (21) is mixed with the incoming gas (2) in a mixing chamber (4). Moistened outgoing gas (5) flows out of an outlet (6). In cases in which the temperature of the incoming gas (2) becomes so high that the temperature of the outgoing gas (5) is above a desired value, the internal desired value is adjusted. The outgoing gas (5) can then cool to the desired value on its way through the inspiration tube (7).

Abstract: A liquid aerosol formulation comprising at least one thermally stable active ingredient selected from the group consisting of butalbital, lorazepam, ipratropium, baclofen, morphine, scopolamine, pharmaceutically acceptable salts and esters thereof and derivatives thereof. The liquid formulation can include an organic solvent such as propylene glycol and one or more optional excipients. The active ingredient can be present in an amount of 0.01 to 5 weight percent and the formulation can be heated to provide a vapor which forms an aerosol having a mass median aerodynamic diameter of less than 3 ?m.

Abstract: A respiratory gas treatment unit includes a humidifier with an induction water heating mechanism. A biocompatible heating target is placed in contact with humidifying liquid held in a humidifying vessel. A magnetic field is generated in close proximity to the heating target to generate heat in the target. The biocompatible heating target can be submerged within the humidifying liquid or can be formed by integrally molding ferromagnetic particles into a plastic wall or floor of the humidifying vessel.

Abstract: An apparatus and method for separating breathable oxygen gas from a source of gas and then humidifying the oxygen gas while preventing over humidification of the oxygen gas, the apparatus comprising a gas pathway located on a first side of a water transfer member, an oxygen gas pathway located on a second side of the water transfer member and a separator for separating the breathable oxygen gas from a gas located on the first side of the water transfer member and directing the breathable oxygen gas past the second side of the water transfer member while maintaining the pressure of the gas substantially equal to the pressure of the breathable oxygen gas to thereby humidify the breathable oxygen gas while preventing a moisture condensation in the breathable oxygen gas.

Abstract: An apparatus is provided for delivering heated and humidified air to the respiratory tract of a human patient for respiratory tract therapy and treatment. The apparatus includes a supply unit (11) and a delivery tube (28) that can be releasably connected to the supply unit (11). Methods of respiratory tract therapy and treatment are also provided.

Abstract: A breathing device includes a housing having an air inlet port, a filtered air outlet port, and a filter situated upstream of the outlet port and downstream of the inlet port. An inhalation valve is situated upstream of the outlet port and downstream of the filter and allows inhalation airflow toward the outlet port, but not vice versa. An aroma-effuser is situated upstream of the inhalation valve and downstream of the filter and entrains aroma in the airflow to be inhaled.

Abstract: A pressure-assisted breathing system is provided that comprises: a pressure-generating circuit for maintaining a positive pressure within the system; a patient interface device coupled to a patient's respiratory system; a respiratory circuit for providing gas communication between the pressure-generating circuit and the patient interface device; means for introducing aerosol particles into the gas flow in the respiratory circuit; and means for discontinuing the introduction of aerosol particles into said respiratory circuit gas flow when the patient exhales. In one embodiment, a flow sensor is disposed in an auxiliary circuit in fluid communication with the respiratory circuit and electronically coupled with a nebulizer. The flow sensor is adapted to detect changes in the volumetric flow rate of gas in the auxiliary circuit when the patient exhales and stops exhaling and sends corresponding electronic signals to the nebulizer to turn off and turn on, respectively.

Abstract: An improved humidifier assembly includes a tubing and a one-way valve for equalizing pressure between gas space of a water supply container and gas space of a humidifier vessel.

Abstract: A breathing circuit component includes an inlet, an outlet and an enclosing wall. The enclosing wall defines a gases passageway between the inlet and the outlet. At least a region of the enclosing wall is formed from a breathable material that allows the passage of water vapor without allowing the passage of liquid water or respiratory gases. The breathing circuit component may be the expiratory limb of a breathing circuit.

Abstract: A humidifier is provided including a first humidifier part, a second humidifier part connectable with the first humidifier part, and a sealing gasket disposed between the first and second humidifier parts. The second humidifier part is configured to hold a volume of liquid therein and the first and second humidifier parts and the sealing gasket define first and second internal passages within the humidifier. The first passage is disposed so as to be exposed to a surface of the volume of liquid and the second passage is isolated from at least one of the first passage and the surface of the volume of liquid. The second passage is configured to communicate with a pressure and/or sound sensing device.

Abstract: An apparatus for delivering humidified gases has a connection manifold adapted to connect with inlet and outlet ports of a slide on water chamber in a single slide on motion. Connection of the gases inlet and gases outlet ports as well as any additional electrical and/or pneumatic connections are all made in the same slide on motion. The water chamber may include inwardly extending elongate extension tubes with one of the extension tubes having an air bleed aperture to aid filling of the chamber.

Abstract: A blister pack for use with inhalation therapy inhalers comprises an elongate bottom element having an overlying top element defining a plurality of spaced top crowned areas containing powder or liquid medications or drugs.

Abstract: An apparatus is disclosed for practicing a method of treating viruses in the nasal mucosa. Vapor is generated, heated and delivered to the nasal mucosa in intermittent bursts, timed to coincide with inhalation. Control circuits are provided to maintain the temperature of the vapor at the point of delivery at a level greater than that necessary to kill viruses in the nasal mucosa. Timing circuits can synchronize the vapor delivery with a breathing cycle with heated vapor being supplied during inhalation and blocked during exhalation. Other circuits terminate operation when liquid is insufficient or after a predetermined timed interval.

Abstract: An apparatus and method for humidification of inspired gases, wherein the present invention utilizes moisture from condensed expiratory gases deposited within the outer expiratory tube of a conventional unilimb breathing circuit to humidify oxygen gas (or any other inspiratory gas) for subsequent patient inhalation, and wherein the oxygen gas may be directed through the outer expiratory tube via a novel reverse flow adapter coupled to an oxygen gas source. The present invention preferably functions to effectively eliminate prior art methods of oxygen gas humidification that depend upon the wasteful utilization of bottles of sterile water, corrugated tubing, nebulizer adapters and excess consumption of oxygen gas; thus, effectuating a cost savings for the patient and contributing to overall environmental conservation efforts.

Abstract: An adjustable air conditioning and regulation apparatus for human respiratory system includes an air treatment assembly and a host controlling assembly. The air treatment assembly has an air filter, a humidity control, a heating device for temperature control and a pressure control. The air filter removes the particles and smells from the air. The clean air is regulated by the controls that maintain the clean air at a desired level of temperature, pressure and humidity. The apparatus provides clean, fresh and comfortable air for the patients with compromised respiratory system.

Abstract: A cool air inhaler for use in treating croup, having a body having at least one side wall and a bottom wall forming an enclosed space open at an upper portion of the body wherein the upper portion of the body is adapted to generally conform to contours of a lower part of a patient face. An air chamber is formed in an upper part of the body and has an exhaust vent for exhausting the patient's exhaled air to an exterior space while an ice reservoir is formed in a lower part of the body to contain ice and meltwater from the ice and an air passage is connected from the exterior space and passing through the ice reservoir to conduct air to the air chamber.

Abstract: A breathing gas humidifier system for a patient includes a replaceable, closed water reservoir (1) with stable pressure, provided for receiving a water reserve for the breathing gas humidifier system. An intermediate storage unit (4) with water is closed from the environment and is located under the water reservoir. The water reservoir (1) and the intermediate storage unit (4) have a valve (16, 14) each, with one of the valves cooperating with the other valve, so that there is a flow connection between the water reservoir (1) and the intermediate storage unit (4) only when the water reservoir (1) is received in a connector (2) of the intermediate storage unit (4). The intermediate storage unit (4) is connected via a water connection line (5) located below the water level to a heated evaporator chamber (7), which opens above the water evaporating at the boiling point into the breathing gas line to a patient.

Abstract: Treatment of pulmonary disorders associated with hypoxemia and/or smooth muscle constriction and/or inflammation comprises administering into the lungs as a gas compound with an NO group which does not form NO2/NOx in the presence of oxygen or reactive oxygen species at body temperature. Treatment of cardiac and blood disorders, e.g., angina, myocardial infarction, heart failure, hypertension, sickle cell disease and clotting disorders, comprises administering into the lungs as a gas, a compound which reacts with cysteine in hemoglobin and/or dissolves in blood and has an NO group which is bound in said compound so that it does not form NO2/NOx in the presence of oxygen or reactive oxygen species at body temperature. Exemplary of the compound administered in each case is ethyl nitrite.

Abstract: An apparatus for humidifying breathable gas includes (a) at least one humidifier part configured to retain a body of liquid therein and defining at least one chamber therein, (b) an inlet communicated with an interior of the at least one humidifier part and connectable to a blower outlet, and (c) an oulet communicated with the interior of the at least one humidifier part and connectable to a patient supply conduit. The at least one chamber is arranged such that liquid from the body of liquid is prevented from exiting the at least one humidifier part through the inlet thereof when the at least one humidifier part is rotated from a working, upright orientation.

Abstract: A disposable active humidifier for the mechanical ventilation of a patient, which has the particularity that it comprises a cartridge which forms a humidification chamber which is delimited by an inlet and by an outlet and can be interposed in the ventilation circuit. The cartridge has an interspace which is externally delimited by a heat exchange surface and is internally delimited by a hydrophobic membrane which surrounds the humidification chamber. A humidification fluid, originating from a bottle or bag, can be introduced in the interspace.

Abstract: A flow probe for use in a humidification system is disclosed. The flow probe is adapted to be positioned in a humidified gases flow (for example oxygen or anesthetic gases) such as that which is provided to a patient in a hospital environment. The flow probe is designed to provide both temperature and flow rate sensing of the gases flow by incorporating two sensors (preferably thermistors) and the shape and alignment of the probe enables accurate readings by reducing the occurrence of condensation on the sensors.

Abstract: A flow probe for use in a humidification system is disclosed. The flow probe is adapted to be positioned in a humidified gases flow (for example oxygen or anaesthetic gases) such as that which is provided to a patient in a hospital environment. The flow probe is designed to provide both temperature and flow rate sensing of the gases flow by incorporating two sensors (preferably thermistors) and the shape and alignment of the probe enables accurate readings by reducing the occurrence of condensation on the sensors.