Abstract: An inhaler article includes a body extending from a mouthpiece end to a distal end with an endpiece element at the distal end. A capsule cavity is defined within the body and extends a cavity length. An air inlet region is between the endpiece element and the capsule cavity. The air inlet region has an air inlet and an air passageway extending from the air inlet to the capsule cavity. The air passageway has an inner diameter less than an inner diameter of the capsule cavity. A porous support element defines a downstream end of the capsule cavity. The porous support element includes one or more apertures extending the length of the porous support element.

Abstract: A compact modular multifunctional inhalation device including a housing having an inlet port and an outlet port; a removable cartridge module adapted to seat within the housing, the cartridge including: a tray within the cartridge for holding a solid inhalant, a heating element mounted within the cartridge above and through the tray for heating the inhalant; and a removable modular electronic circuit adapted to seat within the housing to provide electrical current to the heating element. The heating element is a coil mounted within a chamber in thermal proximity to the solid inhalant. A quartz rod is mounted within the coil. A plunger is mounted within the cartridge to translate therein and compact the solid inhalant. In an alternative embodiment, dual channels and outlet ports are mounted in communication with an inlet port. In another embodiment, the cartridge is a split chamber cartridge with a split plunger mounted therein.

Abstract: A dry powder inhaler for a capsule containing dry powder, the inhaler comprising a housing having a capsule receptacle, two actuator buttons arranged on opposing sides of the housing and two perforation needles, each needle being fixedly connected to an actuator button and movable relative to the housing towards each other from a normal position to a perforation position along an actuation direction to perforate a capsule arranged in the capsule receptacle, wherein a first end of each actuator button is connected to the housing at a lower portion of the housing and in that a second free end of each actuator button is movable into the perforation position such that the perforation needle is moved along a circular line.

Abstract: A lateral flow assay device includes a test strip that is configured to receive a sample fluid and detect a presence of antibodies to one or more of a plurality of proteins of the target pathogen. The lateral flow assay device includes a conjugate pad and a membrane. The conjugate pad contains a plurality of the proteins of the target pathogen, each conjugated with a label. If the sample fluid contains antibodies that are specific to the target pathogen through any of the target pathogen's proteins, a binding takes place between those antibodies and the corresponding tagged protein. The membrane may include a plurality of test lines. Each test line may contain the immobilized binding reagent to one antibody class, resulting in the concentration of all the molecules of that antibody class on the test line.

Abstract: The present disclosure relates to a medical diagnostic and delivery device includes a dipstick type device. The device include cartridge containing one more substance or medicaments configured to be delivered to a user in the form a liquid, particles, or fine mist. In particular embodiments, the device can include a heating element to vaporize the substance and deliver the vapor to a user. In various embodiments, the device includes one or more sensors configured to analyze the one or substances or medications contained within the cartridge and sense, detect or otherwise determine an expiration date of the substance or medication.

Abstract: A disposable assembly and method for providing a liquid chemical for administration which is disposable. The disposable assembly including a tank having an airflow chamber and a liquid chamber, a vaporizer having a first end, a second end, and a movable ring. The first end of the vaporizer is operable to removably attach to the tank. The second end of the vaporizer is operable to removably attach to a battery. Attaching the battery to the second end of the vaporizer actuates the movable ring, and actuating the movable ring introduces air into the liquid chamber of the tank.

Abstract: An electrically operated aerosol-generating system is provided, including an aerosol-generating device, and first and second removable aerosol-forming cartridges each including a resistive heater. The first cartridge includes a first aerosol-forming substrate having a first heating profile and the second cartridge includes a second aerosol-forming substrate having a second heating profile. The device includes a main body defining a cavity and at least one opening configured to removably receive one of the first and second cartridges in the cavity; an electrical power supply and a controller configured to control a supply of electrical current from the power supply to the heater, to detect whether the first or second cartridge has been received within the cavity based upon a resistive load of the respective heater, and to control the supply of electrical current to the heater according to either the first or the second heating profile in response to a detected cartridge.

Abstract: The present invention relates to a dry powder inhaler for administering a medicament via oral inhalation route to a subject. Particularly, the dry powder inhaler according to present invention is suitable for delivering accurate doses of a medicament in different ranges of inspiratory capacity of the subject.

Abstract: A method for the treatment of a neurodegenerative, psychiatric or neurological disease associated with a cholinergic deficit comprising administering GLN-1062 or a pharmaceutically acceptable salt thereof by nasal administration to a patient in need thereof.

Abstract: An inhaler comprising a housing defining a chamber to receive a strip having a plurality of blisters each containing a dose of medicament for inhalation by a user is disclosed.

Abstract: The invention relates to a dispensing device, a storage device and a method for dispensing a medical formulation. Multiple doses of the formulation are stored in a carrier having multiple storage members, each storage member containing a single dose. Each storage member comprises one duct or nozzle for dispensing the respective dose. The dispensing direction of the ducts or nozzles is directed in a lengthwise or indexing direction of the carrier. The storage device of the carrier is a peelable blister strip, wherein the ducts or nozzles can be opened one after the other by peeling the blister strip.

Abstract: An aerosol-generating article is provided, including a nicotine powder receptacle containing a dose of nicotine powder; a corrugated inner wrapper wrapped around the nicotine powder receptacle; an outer wrapper wrapped around the corrugated inner wrapper; at least one airflow inlet upstream of the nicotine powder receptacle; and at least one airflow outlet downstream of the nicotine powder receptacle, wherein corrugations in the corrugated inner wrapper define a plurality of airflow channels in fluid communication with the at least one airflow inlet and the at least one airflow outlet.

Abstract: An aerosol-generating system is provided, including a nicotine source; a volatile delivery enhancing compound source, wherein a volatile delivery enhancing compound comprises an acid; and a heating means for heating one or both of the nicotine source and the volatile delivery enhancing compound source, wherein one or both of the nicotine source and the volatile delivery enhancing compound source is encapsulated in a cylindrical polymeric capsule, and the cylindrical polymeric capsule includes a thermally conductive material.

Abstract: A smoking article has an outer surface and a plurality of frangible microcapsules provided on the outer surface, wherein the microcapsules are capable of being manually ruptured by a consumer to release an odorant encapsulated therein. The smoking article preferably comprises a wrapped tobacco rod; and a filter attached to the wrapped tobacco rod by tipping paper, a mouth end portion of which is “over tipped” with a band or strip of “Peel and Sniff” microcapsules and/or a band or strip of “Scratch and Sniff” microcapsules.

Abstract: An inline dispersal valve that can be used with or without a base. One embodiment includes a rotatable member that is rotatable from a fluid stream obstructing condition to an out-of-the-way condition to prevent fluid diversion into the dispersal valve. Another embodiment includes a lever handle for quickly setting the amount of fluid being diverted into the inline dispersal valve. Another embodiment includes an indicator that can be viewed from a position above the inline dispersal valve. Another embodiment includes a cap that can be secured or removed without the aid of tools. Another embodiment includes a clip that allows one to disassemble the inline dispersal valve for servicing. Another embodiment includes a dispensing valve that can be reversed and still properly divert fluid into a dispersant chamber. Another embodiment includes an inline dispersal valve with a bleed valve positioned to allow one to bring the air volume in the dispersant chamber to the proper level.

Abstract: An improved inhalation device is provided for facilitating inhalation by a patient of powder medicaments contained in a receptacle. The inhalation device includes a staple assembly comprising a plunger and staple that are securely and robustly coupled to one another. Embodiments of the inhalation device have a cap that prevents or reduces the amount of dust and grime entering into the device. The cap is additionally configured to prevent or reduce inadvertent and unintentional operation of the device. The body portion and first casing portion of certain embodiments of the inhalation device are sealably coupled, restricting or reducing undesirable flow pathways that have an adverse effect on the operation of the device.

Abstract: A fluid delivery device (1) for discharging a fluid comprises a housing (2, 3), piston pump (4), biasing mechanism (5, 101), and trigger mechanism (6); the housing (2, 3) comprising a basal end (3) and discharge end (2) having an outlet (10) for discharging the fluid; the piston pump (4) comprising a casing (20) defining a pump chamber (35) for fluid storage, piston (21) slidably movable relative to the pump chamber (35), piston plunger (22), and delivery channel (59) for delivering fluid discharged from pump chamber (35) to outlet (10); the trigger mechanism (6) being movable from cocked configuration, preventing transfer of biasing mechanism (5, 101) force to the casing (20) to prevent casing (20) movement towards the outlet (10), to triggered configuration, enabling transfer of biasing mechanism (5, 101) force to the casing (20) to cause casing (20) movement towards the outlet (10) to discharge fluid from the pump chamber (35).

Abstract: An inhaler, including a base having at least one air-tight, foil-sealed cavity containing medicament is disclosed. An actuator is engagable with a separating element attached to the foil, the actuator having an energized position in which it is biased towards an unloaded position so as to cause the separating element and attached foil to be moved away from the cavity. A latch has a first position, in which it latches the actuator in said energized position, wherein the latch is at least partly arranged in a flow path such that an inhalation flow through the flow path affects the latch to move from the first position to the second position. A method of dispensing a medicament from a sealed cavity inside an inhaler is also disclosed.

Abstract: Device for dispensing a plurality of unitary doses (2) of dry powder, includes at least one support comprising conduits each defining a flow path for an airstream carrying one of the unitary dose (2), the support having first (26) and second (27) members secured to one another so that a first conduit portion (29) of the first member faces a second conduit portions (43) of the second member to define one of the conduits, and a first separation portion (30) of the first member faces a second separation portions (45) of the second member, the support comprising a plurality of barrier-forming elements (31, 46) each arranged between corresponding first (30) and second (45) separation portions to prevent dry powder from passing from one of the conduits to one of the adjacent conduits.

Abstract: A vaginal lubricant comprising high molecular weight hyaluronic acid combined with low molecular weight hyaluronic acid and/or chitosan which has improved stability and which has applications in, for example, maintaining and/or promoting sperm motility.

Abstract: A device outputs portioned medications (M) from individual chambers of a strip arranged one behind the other. The strip includes a base strip and a closure strip and the raised chambers of the strip can be opened by pressing a handle by sharp-edged deflection of the closure strip. In order to simplify the design and for safe operation, a chamber elevation directed toward the mouthpiece opening blocks the actuation of the handle using a blocking element, in which position a chamber arranged in front that has already been freed from the closure strip lies above a fall-through opening, which opening is closed using a flap that can be moved into the opening position by the suction air flow.

Abstract: A nasal delivery device for and method of delivering particulate substance to the nasal airway of a subject, the delivery device comprising: a body assembly (3) including a mouthpiece unit (9) which includes a mouthpiece through which the subject in use exhales, and a substance-supply unit which is fluidly connected to the mouthpiece unit and actuatable to provide particulate substance for delivery to the nasal airway of the subject; wherein the body assembly is configured to receive a replaceable nosepiece unit (5) which includes a nosepiece and contains a container containing particulate substance.

Abstract: A delivery device that includes a cutter for opening a barrier layer to provide fluid access to a dose chamber, and a diverting structure for direct air flow toward the dose chamber.

Abstract: Dry powder inhalers are described with an inhaler body defining an enclosed cavity space and at least one of (a) an endless strip having opposing primary surfaces, the strip comprising a plurality of spaced apart blisters or dose containers holding dry powder medicament. The inhaler also has an inhalation exit flow path in the inhaler body in communication with at least one blister or at least one dose container held by the strip in a dispensing position and a piercer configured to release dry powder medicament from the blister or dose container in the dispensing position.

Abstract: A dry powder inhaler includes a dose container assembly having a dose container disk with opposing upper and lower surfaces, a first row of circumferentially spaced apart dose containers at a first radius and a second row of circumferentially spaced apart dose containers at a second radius. The dose containers have dry powder therein and are sealed via a first flexible sealant over apertures in the upper surface and a second flexible sealant over apertures in the lower surface. A piercing mechanism includes two reciprocating piercers that serially alternate between the two rows of dose containers in the dose container disk. A rotatable ramp disk includes first and second sets of circumferentially spaced-apart ramp elements in staggered, concentric relationship that are configured to move the first and second piercing members between retracted and extended positions.

Abstract: The present disclosure provides an inhaler having a vibration element for aerosolizing medicament contained in a blister pack, wherein individual blister packs are positioned within the housing to be simultaneously engaged with the flow channel and the vibration element. The flow channel includes a blister pack clamping surface that engages the blister pack near the top of the crown and allows the blister three rotational degrees of freedom. The advantages of this arrangement include improved consistency and higher airspeed of the synthetic jet, as well as other advantages.

Abstract: A powder inhaler comprising: a body (10) that is provided with a dispenser orifice; at least one reservoir containing a dose of powder for dispensing; reservoir-opening means for opening a reservoir on each actuation; and a dispersion chamber (70) including an outlet (720) that is connected to said dispenser orifice, and an inlet (710) that is connected to said opening means and that receives the dose of powder from said open reservoir, said dispersion chamber (70) containing at least one movable element (75), such as a ball; the inhaler being characterized in that said dispersion chamber (70) includes a ball path (730) having a width that decreases from said inlet (710) in the direction of displacement of said at least one ball (75).

Abstract: A dispensing device, a storage device and a method are proposed for dispensing a formulation as a spray. The formulation is dispensed by means of a gas stream. To improve the dispensing effect, pressure pulses are generated in the gas stream and/or the direction of gas flow alternates. The formulation is dispensed through a duct. The duct is connected to a storage chamber containing the formulation via a sharp edge or transition portion.

Abstract: A medicine dispensation device, in particular a multi-dose powder inhalator, for the dispensing of individual doses of medicine that has a number of medicine chambers contained in a medicine magazine shaped like a continuous loop. The medicine chambers form groups in such a manner that a mouthpiece reaches the different groups by an essentially complete rotation of the medicine magazine. This enables several medicine chambers—typically one, two or three—to be situated between two successive intake positions, which allows for a high density of medicine chambers and thus creates an inhalation device, which can be handled comfortably even when containing a great number of individual doses.

Abstract: An inhaler is disclosed. It comprises a housing to receive a strip having a surface and a plurality of blister pockets depending from said surface. Each blister pocket contains a dose of medicament for inhalation by a user. The inhaler has a blister strip drive mechanism including a blister strip drive member shaped to contact the strip along a line defined by the crease between a blister pocket and said surface, to drive said strip.

Abstract: An inhaler comprising a housing to receive a strip having a plurality of blisters is disclosed. Each blister has a puncturable lid and contains a dose of medicament for inhalation by a user. A mouthpiece is pivotally mounted to the housing through which a dose of medicament is inhaled by a user. The inhaler also has an actuating mechanism including a lever operable to sequentially move each blister into alignment with a blister piercing member depending from the mouthpiece. The actuating lever is also operable to cause the mouthpiece to pivot so that the blister piercing member punctures the lid of an aligned blister so that, when a user inhales through the mouthpiece, an airflow through the blister is generated to entrain the dose contained therein and carry it, via the mouthpiece, into the user's airway.

Abstract: In an inhaler for administering a powdery medicament in the form of an inhalable substance, substance formulation or mixture, a blister cavity to be opened by piercing elements (11) is mounted in the lower part (1) of a housing (2), which has an upper part (6), designed as mouthpiece and with an inhalation channel (16), and of the lower part (1), which has an air inlet opening (9). The inhalation channel (16) of the upper part (6) of the housing has a unit (15) for dispersing the powdery medicament, said unit (15) being connected to the piercing elements (11), wherein the upper part (6) of the housing can be moved relative to the lower part (1) of the housing in order to open the blister cavity.

Abstract: Inhalers with an inhaler housing having a dose container disk having inner and outer perimeters mounted in the housing. The dose container disk has a plurality of circumferentially spaced apart dose containers with dry powder therein. The inhalers also include a piercer carriage with a piercer mounted in the inhaler. The piercer carriage is in communication with a resilient member that radially biases the piercer carriage to radially travel to align the piercer with an underlying or overlying dose container.

Abstract: A delivery device for and method of delivering a powdered substance, in particular a triptan, such as sumatriptan, to the posterior region of a nasal cavity of a subject, in particular for the treatment of headaches, for example, cluster headaches and migraine, and neuropathic pain, the delivery device comprising: a nosepiece for insertion into a nasal cavity of a subject through which the powdered substance is delivered to the posterior region of the nasal cavity of the subject, in particular the upper posterior two thirds of the nasal cavity; and a substance supply unit which is operable to deliver the powdered substance through the nosepiece.

Abstract: Disclosed is an inhaler, especially a powder inhaler, for administering a medicament in the form of inhalable substances, substance formulations, or substance mixtures. Said inhaler comprises a housing that is provided with a chamber (4) for accommodating the substances. The chamber (4) is replaceably disposed inside the housing.

Abstract: An aerosolization apparatus comprises a housing defining a chamber having one or more air inlets. The chamber is sized to receive a capsule which contains an aerosolizable pharmaceutical formulation. A puncturing mechanism is provided within the housing and comprising a puncture member. The puncture member comprises a forward end shaped to form a cutting edge that is effective in cutting the wall of the capsule to create an opening into the capsule. The puncture member also comprises a trailing end shaped so that it has a non-cutting surface that does not cut the wall of the capsule when the trailing end is inserted into the opening created by the forward end. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the capsule through the opening created in the capsule.

Abstract: A device for dispensing individual doses of powder from respective pockets of a disc-shaped carrier by outwardly rupturing a lidding foil by means of pressure on an opposite side surface, the device providing individual respective deaggregation flow paths for each pocket, split airstreams allowing improved entrainment of powder, a cam mechanism for outwardly rupturing the pockets, an indexing mechanism linked to the cam mechanism and a dose counter.

Abstract: A fluid dispenser device comprising a body (10) provided with a dispenser orifice (15), said device further comprising: an elongate flexible strip (20) supporting a plurality of reservoirs (21) each containing a dose of fluid; reservoir-opening means (80) for opening a respective reservoir on each actuation; first displacement means (30) for causing said flexible strip (20) to advance before and/or during and/or after each actuation, so as to bring a full reservoir into register with said reservoir-opening means; and second displacement means (50) for displacing a full reservoir (21) against said opening means (80) each time the device is actuated, said device including positioning means (300) that are adapted to position the full reservoir accurately relative to the reservoir-opening means (80) when it is displaced thereagainst, so as to guarantee that opening is predetermined and reproducible on each actuation.

Abstract: A dry powder inhaler comprises two parts (2, 4) connected by an integrally molded, e.g. living hinge (6), so as to be moveable from an open position to a closed position. At least one of the parts (2, 4) defines at least part of a circulating airflow chamber (12), wherein when said parts (2, 4) are in said closed position, the inhaler comprises an airflow path including the circulating airflow chamber (12).

Abstract: The present invention provides for the integration of drug dispersion methods into a drug or medicine delivery system. The drug dispersion methods used include shear (e.g., air across a drug, with or without a gas assist), capillary flow or a venturi effect, mechanical means such as spinning, vibration, or impaction, and turbulence (e.g., using mesh screens, or restrictions in the air path). These methods of drug dispersion allow for all of the drug in the system to be released, allowing control of the dosage size. These methods also provide for drug metering, fluidization, entrainment, deaggragation and deagglomeration. The present invention also provides for the integration of a drug sealing system into the device. The drug sealing system provides a way of blocking the migration of drug from one area of the package to another.

Abstract: The present invention relates to an inhaler for administering a defined dose of an active ingredient into the respiratory tracts of a user. The inhaler has an elongate shape defining a longitudinal axis and a cross-sectional profile, wherein the maximum cross-sectional area is at most 4 cm2 and the maximum extension of the cross-section is at most 2.85 cm.

Abstract: The invention relates to a capsule for receiving a preferably powdered pharmaceutical preparation and an inhaler in which, for inhalation, the preparation is expelled from the capsule through at least one hole. A capsule according to the invention comprises as capsule elements a capsule cap and a capsule body, at least one of which comprises at least one prefabricated hole. Systems according to the invention comprising inhalers and capsules are described, in which the prefabricated hole in the capsule is sealed off in the transporting state of the system and is open in the usage state. The hole is exposed by actuation of a pushing or pulling mechanism. Prior to this the hole is closed off by part of the capsule itself or by a capsule receptacle belonging to the inhaler. In one embodiment the capsule may be present in two different states, for example in different insertion positions of the capsule elements. In the first state the prefabricated hole is closed off and in the second it is exposed.

Abstract: An inhaler is disclosed. It comprises a housing to receive a strip having a plurality of blisters, each blister having a breachable lid and containing a dose of medicament for inhalation by a user, an indexing wheel mounted in the housing rotatable to drive a strip to sequentially move blisters into alignment with a blister piercing member, a control element pivotally mounted to the housing and a drive mechanism configured to couple the control element to the indexing wheel during part of the rotation of the control element by a user so that the indexing wheel rotates together with the control element.

Abstract: An inhaler comprising a housing to receive a strip having a plurality of blisters is disclosed. Each blister has a puncturable lid and contains a dose of medicament for inhalation by a user. A mouthpiece is pivotally mounted to the housing through which a dose of medicament is inhaled by a user. The inhaler also has an actuating mechanism including a lever operable to sequentially move each blister into alignment with a blister piercing member depending from the mouthpiece. The actuating lever is also operable to cause the mouthpiece to pivot so that the blister piercing member punctures the lid of an aligned blister so that, when a user inhales through the mouthpiece, an airflow through the blister is generated to entrain the dose contained therein and carry it, via the mouthpiece, into the user's airway.

Abstract: An inhaler for delivery of a powder-form inhalation formulation from a blister strip with a plurality of blister pockets containing the inhalation formulation in doses. The inhaler comprises a metallic piercing member with two piercing elements extending parallel to each other and inclined to the lid of a blister pocket to be punctured. To operate the inhaler, an air stream of ambient air can be sucked or delivered in order to discharge the respective dose from an opened blister pocket and to deliver the dose with the ambient air as an aerosol cloud.

Abstract: The present disclosure provides an inhaler having a vibration element for aerosolizing medicament contained in a blister pack, wherein a plurality of individual blister packs are arranged in a rotary cassette that fits within a housing, and wherein the individual blister packs are dragged up into a clamping position between the vibration element and a piercing element. The motion of the blister pack is controlled by a rotary disk within the housing which further coordinates the movement of the piercing and vibrating elements for the piercing and deaggregation, respectively, of the individual blister packs.

Abstract: The present invention provides for the integration of drug dispersion methods into a drug or medicine delivery system. The drug dispersion methods used include shear (e.g., air across a drug, with or without a gas assist), capillary flow or a venturi effect, mechanical means such as spinning, vibration, or impaction, and turbulence (e.g., using mesh screens, or restrictions in the air path). These methods of drug dispersion allow for all of the drug in the system to be released, allowing control of the dosage size. These methods also provide for drug metering, fluidization, entrainment, deaggragation and deagglomeration. The present invention also provides for the integration of a drug sealing system into the device. The drug sealing system provides a way of blocking the migration of drug from one area of the package to another.

Abstract: A fluid dispenser device including a body (10), an elongate flexible strip (20) supporting a plurality of reservoirs (21), a reservoir opening mechanism (30); a first displacement mechanism (40) for causing the flexible strip to advance so as to bring a full reservoir into register with the reservoir-opening mechanism; and a second displacement mechanism (45) for displacing a reservoir (21) against the reservoir opening mechanism (30). The leading end (25) of the flexible strip (20), in the advance direction of the strip is fastened to a receiver element (50), which is displaceable on a path along a guide mechanism (100), between a first position that corresponds to the first actuation of the device and a second position that corresponds to the last actuation of the device.

Abstract: Inhaler for inhaling powdered medicaments from capsules, comprising a lower part (6), a plate (3) accommodated in the lower part (6), and a holder (18) inserted in the lower part (6), a mouthpiece (2) that can be latched to the lower part (6) on the plate (3), a cover (1) that covers the mouthpiece (2) in a closed position and latches by means of a closure element (14), the lower part (6) and the cover (1) being rotatably (4) connected to one another by a spindle (4), and an actuating member (7, 10) that can be moved from a resting position and set in motion and at the same time co-operates with at least one pin (8, 11) that can be stuck into the holder (18) and is located in a pin holder in the inner actuating member (10). In the holder (18) an exchangeable tube (22) can be inserted, as expulsion channel, which comprises a capsule chamber (21) with the capsule.

Abstract: An aerosolization apparatus comprises a housing defining a chamber having a plurality of air inlets. The chamber contains an aerosolizable pharmaceutical formulation or is sized to receive a receptacle which contains an aerosolizable pharmaceutical formulation. A shield covers at least one of the air inlets or a portion of at least one of the air inlets. The shield prevents blockage of the air inlet by a user grasping the apparatus and inadvertently covering the air inlet. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the receptacle.