Hetero Nitrogen Ring Contains At Least Two Hetero Atoms Patents (Class 204/157.72)
  • Patent number: 10618027
    Abstract: A method of decoloring an ionic liquid includes preparing a discolored ionic liquid, and decoloring the discolored ionic liquid through irradiation with UV rays. An ionic liquid that is discolored due to heat treatment upon purification is decolored and can thus be reused. The method of decoloring the ionic liquid is effective because an ionic liquid, which is discolored due to heat treatment upon purification, can be decolored in a simple manner and also because an ionic liquid, which is discolored and is thus difficult to apply to the purification of an organic material, can be decolored in a simple manner, and can thus be reused in the form of a high-purity ionic liquid.
    Type: Grant
    Filed: February 14, 2017
    Date of Patent: April 14, 2020
    Assignee: INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY
    Inventors: Dong-Chan Shin, Ki-Hyun Kim, Yong-Taeg Oh
  • Patent number: 10174063
    Abstract: Compositions and methods comprising metal organic frameworks (MOFs) and related uses are generally provided. In some embodiments, a MOF comprises a plurality of metal ions, each coordinated with at least one ligand comprising at least two sets of ortho-diimine groups arranged about an organic core.
    Type: Grant
    Filed: May 6, 2015
    Date of Patent: January 8, 2019
    Assignee: Massachusetts Institute of Technology
    Inventors: Mircea Dinca, Dennis Sheberla, Lei Sun, Casey R. Wade, Michael Glenn Campbell
  • Patent number: 8877018
    Abstract: The present teachings describe a process for converting a HOGaPc Type I polymorph to the HOGaPc Type V polymorph. The process includes obtaining a slurry comprising hydroxy gallium phthalocyanine (HOGaPc) Type I polymorph. The slurry is mixed at a resonant frequency of the slurry by applying a low frequency acoustic field for a time sufficient to convert the HOGaPc Type I polymorph to the HOGaPc Type V polymorph.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: November 4, 2014
    Assignee: Xerox Corporation
    Inventors: Sarah J. Robinson, Marko Saban, Yulin Wang, Sandra J. Gardner, Cuong Vong
  • Publication number: 20130323642
    Abstract: The present invention includes a composition comprising an alkyne-based substrate, an azide-based substrate, a Cu(II) salt and a photoinducible reducing agent. The present invention further includes a method of immobilizing a chemical structure in a given pattern onto a section of the surface of a solid substrate, using the photoinducible Cu(I)-catalyzed azide-alkyne cycloaddition Click reaction.
    Type: Application
    Filed: November 28, 2011
    Publication date: December 5, 2013
    Applicant: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
    Inventors: Christopher Bowman, Christopher J. Kloxin, Brian J. Adzima
  • Publication number: 20120022091
    Abstract: The present invention relates in general to the field of organic chemistry and in particular to the preparation of N-(4-(4-fluorophenyl)-6-isopropyl-5-methylpyrimidin-2-yl)-N-methylmethanesulfonamide (I), N-(4-(4-fluorophenyl)-5-(bromomethyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide (II) and N-(4-(4-fluorophenyl)-5-(hydroxymethyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide (III), key intermediates in preparation of Rosuvastatin.
    Type: Application
    Filed: February 1, 2010
    Publication date: January 26, 2012
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Zdenko Casar, Janez Kosmrlj
  • Publication number: 20110195028
    Abstract: The presently disclosed subject matter demonstrates that a spin state which has zero magnetic resonance signal, but an extremely long lifetime, can be used to store magnetization, which can then be recovered into an observable transition. Coupled with hyper-polarization techniques, this permits the preparation of a wide range of contrast agent molecules for use in magnetic resonance imaging (MRI) techniques that have long effective relaxation time.
    Type: Application
    Filed: July 31, 2009
    Publication date: August 11, 2011
    Inventor: Warren S. Warren
  • Patent number: 7993494
    Abstract: A novel synthesis method of a triarylpyrazine derivative, in particular, a manufacturing method by which a triarylpyrazine derivative, in specific, a 2,3,5-triarylpyrazine derivative in which an aryl group at a 5-position includes a substituent having an electron-withdrawing property can be synthesized with high yield as compared to a conventional method is provided. By using a synthesis method in which a mixture including a 1-aryl-2-(methylsulfinyl)ethanone derivative, meso-1,2-diarylethylenediamine, and a dehydrogenation agent is irradiated with a microwave to be reacted, the above object is achieved.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: August 9, 2011
    Assignee: Semiconductor Energy Laboratory Co., Ltd.
    Inventors: Hideko Inoue, Hiroko Nomura
  • Publication number: 20110168543
    Abstract: Advantageous microwave-assisted methods for synthesis of fluorinated phthalocyanines are provided. The microwave-assisted methods offer enhanced yields, substantially eliminate reaction solvents, and facilitate purification relative to conventional synthesis techniques. Typical implementation involve a reaction mixture that includes perfluoro-phthalonitrile that is reacted in a vessel with application of microwave energy for a reaction period sufficient to yield a fluorinated phthalocyanine. The fluorinated phthalocyanines synthesized according to the disclosed microwave-assisted methods have wide ranging applications, e.g., corrosion-related applications, coating-related applications, catalysis, and the production of optical and electronic materials.
    Type: Application
    Filed: April 1, 2009
    Publication date: July 14, 2011
    Applicants: NEW JERSEY INSTITUTE OF TECHNOLOGY, FRAUNHOFER-GESELLSCHAFT
    Inventors: Sergiu M. Gorun, Guenter Schnurpfeil, Olaf Hild, Dieter Woehrle, Olga Gerdes, Robert Gerdes
  • Publication number: 20110105760
    Abstract: The present invention relates to a process for preparing substituted 2-aminobiphenyls and to a process for preparing (Het)arylamides of such 2-aminobiphenyls.
    Type: Application
    Filed: July 3, 2009
    Publication date: May 5, 2011
    Applicant: BASF SE
    Inventors: Michael Keil, Michael Rack, Thomas Zierke, Markus Heinrich, Alexander Wetzel
  • Publication number: 20100219063
    Abstract: The present invention relates to oxidative degradation products of atorvastatin calcium and the process of the preparation thereof. The present invention also relates to atorvastatin calcium substantially free of oxidative degradation products and the pharmaceutical compositions containing such atorvastatin calcium.
    Type: Application
    Filed: April 30, 2010
    Publication date: September 2, 2010
    Applicant: Lek Pharmaceuticals D.D.
    Inventors: Rok GRAHEK, Darko Kocjan, Andrej Bastarda, Andrej Kocijan, Matjaz Kracun
  • Publication number: 20100096252
    Abstract: The present invention relates to photolabile or photoreleasable compounds including a caging moiety linked to an effector moiety, wherein the compounds are capable of releasing the effector moiety on irradiation, typically by flash irradiation with light. These compounds are particularly suitable for focal 2-photon uncaging The photoreleasable compounds can be used to deliver effector moieties such as carboxylic acids, preferably, neuroactive amino acids to sites where their activity is required. In preferred embodiments of the invention, the caging moiety is based on 4-carboxymethoxy-5,7-dinitroinlinyl and derivatives thereof.
    Type: Application
    Filed: January 29, 2008
    Publication date: April 22, 2010
    Applicant: PHILADELPHIA HEALTH & EDUCATION CORPORATION, d/b/a DREXEL UNIVERSITY COLLEGE OF
    Inventor: Graham Ellis-Davies
  • Publication number: 20090288992
    Abstract: The present invention relates to an ionic liquid compound of general formula C+A?, where C+ represents an organic cation such as alkyl-pyridinium, di-alkyl imidazolium and tri-alkyl imidazolium; and A? is an anion of halides of iron (III), such as, for example, FeCl4? and to a method of producing the ionic liquid compound by heating the reactants using microwave energy. The ionic liquids can be used to desulfurize hydrocarbon mixtures by a liquid-liquid extraction.
    Type: Application
    Filed: May 26, 2009
    Publication date: November 26, 2009
    Applicant: INSTITUTO MEXICANO DEL PETROLEO
    Inventors: Natalya Victorovna Likhanova, Rafael Martinez Palou, Jorge Froylan Palomeque Santiago
  • Publication number: 20090183982
    Abstract: A novel synthesis method of a triarylpyrazine derivative, in particular, a manufacturing method by which a triarylpyrazine derivative, in specific, a 2,3,5-triarylpyrazine derivative in which an aryl group at a 5-position includes a substituent having an electron-withdrawing property can be synthesized with high yield as compared to a conventional method is provided. By using a synthesis method in which a mixture including a 1-aryl-2-(methylsulfinyl)ethanone derivative, meso-1,2-diarylethylenediamine, and a dehydrogenation agent is irradiated with a microwave to be reacted, the above object is achieved.
    Type: Application
    Filed: January 15, 2009
    Publication date: July 23, 2009
    Inventors: Hideko Inoue, Hiroko Nomura
  • Publication number: 20080319187
    Abstract: Provides is a porphylleren compound (and methods for preparation thereof) according to formula (I) where the residues A1, A2 A3, and A4 independently are a group containing 1 to 40 carbon atoms and at least one carboxylic group, the residues R, R? and R? independently are hydrogen or a group containing 1 to 80 carbon atoms, M is 2 H or an element capable of complexing with pyrrole nitrogen atom and L is a linking group and B is a fullerene residue.
    Type: Application
    Filed: May 19, 2008
    Publication date: December 25, 2008
    Inventors: Saeed Sarkar, Seyed Mahdi Rezayat, Anatoly Leonidovich Buchachenko, Dmitry Anatolevich Kuznetsov, Marina Alexeyevna Orlova, Marina Abramovna Yurovskaya, Igor Viktorovich Trushkov
  • Patent number: 6712972
    Abstract: The present invention provides an innovative method based on reaction cum separation on single plate concept for efficient evaluation of porphyrins, calix(4)pyrroles and allied macrocycles by in-situ synthesis from pyrrole with aromatic aldehydes and ketones over zeolite based molecular sieve catalysts as sorbents in thin layer chromatography (TLC) using microwave heating. This glass backed zeolite coated TLC plate acts as a micro reactor as well as separator for the in-situ synthesis and chromatographic separation of macrocycles. The process is simple, economical, rapid, selective and finds a possible application in high throughput parallel synthesis and screening on a single micro plate employing microwave irradiation.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: March 30, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Sita Devi Pothuri, Kondapuram Vijaya Raghavan, Shivanand Janardan Kulkarni, Radha Kishan Motkuri, Radha Rani Vippagunta, Mamidanna Rama Venkata Satyanarayana Murty
  • Patent number: 6605194
    Abstract: The present invention relates to novel calix pyrroles and a process for synthesis of calix (4) pyrroles by reacting pyrrole with cyclic or acyclic ketones in dichloro methane (DCM) solvent over molecular sieve catalysts which provides an eco-friendly, more economical and selective heterogeneous method.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: August 12, 2003
    Assignee: Council of Scientific and Industrial Research
    Inventors: Kondapuram Vijaya Raghavan, Shivanand Janardan Kulkarni, Motkuri Radha Kishan, Nagabandi Srinivas
  • Patent number: 6551467
    Abstract: The present invention is draw to microwave heating of a transition metal-catalysed organic reaction, in which a catalyst complex between a transition metal and an auxiliary ligand or ligands, the ligand being asymmetric or symmetric, monodentate or bidentate, results in highly chemoselective, regioselective, and stereoselective allylic substitution reactions. Molybdenum or palladium complexes form suitable catalytic systems with a plethora of ligands in a variety of solvents for such microwave facilitated nucleophilic substitution reactions.
    Type: Grant
    Filed: April 16, 2001
    Date of Patent: April 22, 2003
    Assignee: Personal Chemistry i Uppsala AB
    Inventors: Ulf Bremberg, Anders Hallberg, Mats Larhed, Christina Moberg, Nils-Fredrik Kaiser
  • Patent number: 6524446
    Abstract: The present invention provides an improved process for synthesis of porphyrin compounds of the general formula 1 from pyrrole and aromatic aldehyde over zeolite molecular sieve catalysts using microwave heating, (solvent free) to provide an eco-friendly, economical, faster and selective heterogeneous method.
    Type: Grant
    Filed: March 27, 2001
    Date of Patent: February 25, 2003
    Assignee: Council of Scientific and Industrial Research
    Inventors: Shivanand Janardan Kulkarni, Kondapuram Vijaya Raghavan, Radha Kishan Motkuri, Srinivas Nagabandi
  • Publication number: 20030010621
    Abstract: This invention provides a novel process for preparing soluble phthalocyanines by microwave irradiation in the absence of any organic solvent. Three different starting materials, i.e. t-butylphthalic anhydride, t-butyl phthalonitrile and metal-free H2Pc (tetra-t-butylphthalocyanine) have been adopted , respectively. The starting material with proper metal compound, such as chloride or acetate were irradiated in a commercial microwave oven for a period of 1 to 30 minutes at a power of 200˜900 W. This process is noted to reduce drastically reaction time of MPc formation from 8˜24 hours to 10˜30 minutes due to its unique heating by microwave irradiation. Sandwiched type MPc2(such as Lu Pc2) can be produced only through metal replacement from metal-free phthalocyanine by microwave irradiation.
    Type: Application
    Filed: June 26, 2001
    Publication date: January 16, 2003
    Inventors: Andrew Teh Hu, Tsai-Wie Tseng, Herng-Dar Hwu, Lung-Chang Liu, Chung-Chun Lee, Ming-Chia Lee, Jun-Rong Chen
  • Patent number: 6491796
    Abstract: This invention provides a novel process for preparing soluble phthalocyanines by microwave irradiation in the absence of any organic solvent. Three different starting materials, i.e. t-butylphthalic anhydride, t-butyl phthalonitrile and metal-free H2Pc (tetra-t-butylphthalocyanine) have been adopted, respectively. The starting material with proper metal compound, such as chloride or acetate were irradiated in a commercial microwave oven for a period of 1 to 30 minutes at a power of 200˜900 W. This process is noted to reduce drastically reaction time of MPc formation from 8˜24 hours to 10˜30 minutes due to its unique heating by microwave irradiation. Sandwiched type MPc2 (such as Lu Pc2) can be produced only through metal replacement from metal-free phthalocyanine by microwave irradiation.
    Type: Grant
    Filed: June 26, 2001
    Date of Patent: December 10, 2002
    Assignees: Agi Corporation, National Tsing Hua University
    Inventors: Andrew Teh Hu, Tsai-Wie Tseng, Herng-Dar Hwu, Lung-chang Liu, Chung-Chun Lee, Ming-Chia Lee, Jun-Rong Chen
  • Publication number: 20020143175
    Abstract: The present invention provides an improved process for synthesis of porphyrin compounds of the general formula 1 1
    Type: Application
    Filed: March 27, 2001
    Publication date: October 3, 2002
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Shivanand Janardan Kulkarni, Kondapuram Vijaya Raghavan, Radha Kishan Motkuri, Srinivas Nagabandi