Abstract: A catheter assembly includes a catheter, a coating, a fluid containing sleeve, and a container. The catheter may include one or more distal drainage openings. The coating may be disposed on an outer surface of the catheter. The fluid containing sleeve may have an outer foil layer and be configured for positioning over the outer surface of the catheter to maintain the coating in a hydrated state. The container may enclose the catheter and the fluid containing sleeve. Substantially all fluid in the container may be disposed in the fluid containing sleeve.

Abstract: A ready to use catheter assembly comprises a catheter package with an opening, a catheter with a shaft arranged in the catheter package so a distal end of the catheter lies in the region of the opening, and a protective sleeve which partly covers the catheter shaft, a first end of the protective sleeve fixed to the distal end of the catheter. A method for producing a ready to use catheter assembly and a ready to use catheter assembly which further reduces the risk of an accidental contamination of a catheter when pulling it out of the catheter package prior to the insertion into the urethra of a user are provided. The opening has a defined maximum opening length, a second end of the protective sleeve is releasably connected which the catheter package near the maximum opening length of the opening and the protective sleeve is in a retracted state.

Abstract: A catheter package and method of use which serve to straighten a curved catheter shaft. The straightening of the catheter shaft may be accomplished by passing the shaft through a pathway that bends the catheter in the opposite direction of the curvature imparted to the catheter shaft. The catheter shaft pathway may incorporate various shaped bumps, ridges, pins or rollers or other features which assist in straightening the shaft.

Abstract: Embodiments of this disclosure include systems, methods, and kits for sterilizing in vivo catheters using an optical fiber to deliver UV light. In an embodiment, a method for sterilizing a catheter with at least a first lumen, includes inserting a distal end of a fiber optic cable into a fiber insertion port of a catheter connector attached to a hub of the first lumen, flushing the first lumen with fluid from a fluid source, inserting the fiber optic cable into the first lumen until a stopper of the fiber optic cable is adjacent to the fiber insertion port, providing light to the fiber optic cable from a light source after the fiber optic cable is inserted into the first lumen, withdrawing the fiber optic cable from the first lumen while the light is provided, and ceasing to provide light to the fiber optic cable after the fiber optic cable is withdrawn from the first lumen. The disclosure is also applicable to catheters with multiple lumens and to catheters accessed through subcutaneous ports.

Abstract: This disclosure describes example antimicrobial compositions that may be used in combination with IV port cleansing caps, protective caps, or both. According to another implementations, the disclosure describes various cap devices that may be used in combination with the antimicrobial composition to cleanse, sanitized, and/or disinfected a surface.

Abstract: This application describes example antimicrobial compositions that may be used alone or in combination with catheters and catheter insertion sites. According to another aspect, the application describes catheters which may employ one or more protection devices, such as cleaning caps, protective caps or both.

Abstract: The present invention relates to a catheter securement device and securement device assembly for a securing a catheter relative to a patient. The securement device includes a base having an opening configured for receipt of the catheter, a cover member configured with the base over the opening, and a lip configured around at least a portion of the base. The base is configured for attachment to a patient's skin over a catheter insertion site and includes a top surface and a bottom surface. The opening of the base is configured to accommodate a catheter inserted therethrough from the catheter insertion site. The cover member is movable from an open position to a closed position over the catheter insertion site and is configured to secure the catheter. The lip is configured on the bottom surface of the base around the opening such that the lip reduces leakage from the catheter insertion site when the securement device is secured to the patient's skin.

Abstract: Systems and methods encourage users to rotate injection sites and avoid lipodystrophy. Sleeves and/or lost-tooth gear dials and/or microswitches in or on injection pens or their caps, on vials, and on other portable devices manually adjust an indicator before or after an injection to show a current or next injection site in accordance with a site rotation plan. Injected medicine packaging and related printed indicia encourage site rotation. Optical devices employing optical mouse or projection technology help locate and/or distribute injection sites within a body area. A mobile phone app tracks injections and locations to select next injection site, and can use imaging to locate a target injection site and optionally diagnose lipodystrophic conditions and record them. Tactile and print media educational tools are presented to help users palpate and identify lipos in body areas having injection sites.

Abstract: A single dose material and applicator package that is easily held for removal of a cover and that contains an easily removable applicator. A tray has an applicator well and a material well. Formed in the applicator well is a finger depression adjacent the material well and an applicator support depression adjacent an opposing end of the applicator well. The finger depression permits easy grasping of the tray for removing the cover. The applicator support depression acts as a fulcrum to pivot or lever the applicator out of the tray when a force is applied to one end of the applicator. A material well ramp permits a controlled amount of material to be placed on the applicator brush.

Abstract: A pharmaceutical waste disposal assembly (10) for disposing of raw pharmaceutical waste includes a receiver body (19) and a first reaction agent (287). The receiver body (19) is configured to receive the pharmaceutical waste. The receiver body (19) includes a body interior wall (921A) that defines a body interior (921B). The first reaction agent (287) is positioned within the body interior (921B) so that the first reaction agent (287) contacts the body interior wall (921A) prior to receiving the pharmaceutical waste. The first reaction agent (287) chemically reacts with the pharmaceutical waste so that the pharmaceutical waste is rendered unrecoverable. The first reaction agent (287) can include at least one of a denaturant and a deterrent. Additionally, the first reaction agent (287) can include activated charcoal.

Abstract: An apparatus and a method for sheathing a medical device, tool, instrument or probe (generally, probe) is provided. Among other aspects, a probe support jig capable of supporting the probe is provided, which includes a mechanical coupling for accepting a sheath on a sheath shell. In use, the sheath shell is coupled at one end thereof to the support jig and the probe is fed into the sheath, which is coupled to the sheath shell at another end thereof.

Abstract: A syringe packaging system that includes a tube and a cap for enclosing a pre-filled syringe is disclosed. The tube includes a tube cut flange and the cap includes a cut skirt. With a syringe barrel contained within the tube, a syringe barrel cut flange is aligned with the tube cut flange. With the pre-filled syringe enclosed within the tube and the cap, the cut skirt of the cap surrounds the syringe barrel cut flange. In one embodiment, a film is securable to a portion of the tube and a portion of the cap to connect the tube and the cap with the pre-filled syringe enclosed within the cap and the tube.

Abstract: A syringe packaging system including a shell for enclosing a pre-filled syringe is disclosed. The shell includes a first portion having a proximal end and a distal end having a disk-shaped bottom portion; and a second portion having a proximal end and a distal end. With the first portion engaged with the second portion to form the shell, the proximal end of the first portion and the proximal end of the second portion together define a syringe flange having a top wall that defines a shell proximal aperture, a bottom wall, and a sidewall.

Abstract: A single use delivery device is disclosed having a manually deformable liquid container defining an inner chamber, the container having a distal end, a body, a proximal end, and an outlet on the distal end; a tip projecting from the outlet on the distal end of the container, the tip in fluid communication with the inner chamber of the container; and a primer element for removing one or more air bubbles from the chamber, said primer element being attached to and in fluid communication with the deformable container. A method of administering a fluid to or flushing a vascular access device using a single use pre-filled delivery device as described herein is also disclosed.

Abstract: A system and method for pumping fluid using a pump cassette is disclosed. The system includes a control assembly for operating the pump cassette. A force assembly having a movable member is capable of applying force to the pump cassette to press the pump cassette against the control assembly. The movable member may be an expandable member, such as a bladder.

Abstract: A device comprises a cylinder and a tank. The cylinder includes a first disc and a second disc, multiple struts arranged orthogonally between the first disc and the second disc, and a plurality of walls, parallel to the first disc and the second disc. The struts generally form a circumference with spaces between each of the struts along the circumference; the walls extend through the space between the struts and beyond the circumference of the struts; and the walls form a plurality of tracks around the circumference of the struts. An axle extends orthogonally between the first disc and the second disc, and at least a portion of the cylinder rotates about the axle. The tank includes a basin to hold a liquid solution. When a catheter is wound around the cylinder, the rotation of the cylinder causes the catheter to be coated in the liquid solution from the basin.

Abstract: A device that stores, secures, and disinfects hazardous materials introduced therein, comprising a container having at least one interior surface, wherein the at least one interior surface forms at least one chamber within the container for storing the hazardous materials introduced into the container; at least one port having an aperture and unidirectional access for introducing the hazardous materials into the container and preventing outflow of the hazardous materials from the container; an absorbent material for securing the hazardous materials introduced into the container, wherein the absorbent material is affixed to the at least one interior surface of the container; and a disinfecting substance for disinfecting the hazardous materials introduced into the container, wherein the disinfecting substance is affixed to the at least one first interior surface of the container.

Abstract: A syringe assembly including a plunger rod having a first end, a second end, and a rod portion extending therebetween, wherein at least a portion of the rod portion is flexible is disclosed. The flexible portion of the rod portion allows a stopper to be moved between a first position and a second position within a syringe barrel while the overall length of the syringe assembly remains the same throughout the movement between the first position and the second position. In another embodiment, a syringe assembly including a restraining member adapted to communicate with the flexible portion of the rod portion such that movement of the first end of the plunger rod in a first direction actuates movement of the second end of the plunger rod in a second direction different than the first direction is disclosed.

Abstract: A tray (100) for accommodating a coiled medical device, such as a catheter assembly (700), includes a first compartment (101), a second compartment (102), and a third compartment (103). The catheter assembly (700) and devices associated with a catheterization procedure, such as syringes (701,702) containing sterile water and lubricating jelly and a specimen container (703) can be disposed within the tray. A first barrier (105) and second barrier (106) separate the compartments. The barriers can have openings (121,122) therein to accommodate large syringes or to enable the first compartment (101) to be used as a lubricant applicator for the catheter. The first compartment (101) can include a stair-stepped contour (115) such that the syringes are held at different depths to facilitate ease of use. The various devices can be disposed within the tray (100) in accordance with their order of use in the catheterization procedure.

Abstract: A catheter assembly includes a hydrophilic catheter; a wetting fluid for wetting of the catheter; and a receptacle enclosing at least the insertable part of the catheter and the wetting fluid. The wetting fluid is a solution incorporating at least one osmolality-increasing compound, and the total concentration of the osmolality-increasing compound(s) preferably exceeds 600 mOsm/dm3. The wetting fluid could either be arranged in contact with the hydrophilic surface layer of the catheter in the receptacle, for preservation of the hydrophilic surface layer in a wetted state during accommodation in said receptacle and provision of a ready-to-use catheter assembly, or be arranged to keep the wetting fluid separated from the hydrophilic surface layer of the catheter during storage, but to be brought into contact with said hydrophilic surface layer upon activation before an intended use of the catheter.

Abstract: A hydrophilic intraocular lens storage system includes: a) a substantially air tight container containing a small quantity of free water; and b) a foldable hydrophilic intraocular lens disposed within the container at a location wherein the lens is not immersed in liquid. The storage system can be employed to maintain the hydrophilic intraocular lens in a foldable state without being immersed in liquid. The method includes the step of storing the foldable intraocular lens within a substantially air tight package containing free water, the lens being stored within the package at a location wherein the lens is not immersed in liquid.

Abstract: The invention relates to an assembly comprising a transparent “outer” packaging element (1) defining a chamber, and an “inner” packaging element (2) received in said chamber of the outer packaging element (1). Said inner packaging element (2) comprises at least first and second packaging portions (21, 22) that are transparent, each of which has at least one cavity (41, 42) for receiving an article, and a sealing sheet that is at least partially opacifying, and that comprises two portions applied over the two packaging portions (21, 22) in such a manner as to close said cavities (41, 42). The two packaging portions (21, 22) of the inner packaging element (2) are folded over towards each other towards a configuration in which the two portions of said sealing sheet applied over the two packaging portions (21, 22) of the inner packaging element (2) face each other.

Abstract: A urinary catheter is configured to avoid sliding contact between the outer surface of a catheter tube and the urethra wall. A flexible tubular membrane extends through the catheter tube and has a proximal end secured to an anchor outside the urethra as the catheter tube moves into the urethra, pulling the membrane through the proximal end of the tube so it inverts and covers the outer surface of the tube. Alternatively, a catheter tube of flexible material has a proximal end secured to the anchor, and the catheter tube turns inside out as it is inserted, forming a double wall reflected tube with a proximal reflection point. The sterile interior surface of the membrane or tube becomes the external surface facing the urethral wall as the catheter is deployed, and this external surface maintains static contact with the urethral wall as the catheter is advanced or retracted.

Abstract: An integrated individual package and an introducer needle or wire for placing a catheter in a patient's vasculature, wherein the package doubles as a grip for placing the catheter. Prior to activation, the catheter is coaxially and slidably disposed over the introducer needle and the catheter and introducer needle assemblies are contained within the integrated package grip. The device is activated as the catheter and introducer needle assemblies are simultaneously transitioned from a closed position to an open position wherein the catheter and introducer needle assemblies are oriented for insertion into a patient's vasculature. Following placement of the catheter in a patient's vasculature, the device is deactivated as the introducer needle is withdrawn and transitioned from the open position to resume the closed position. The package grip comprises a sharps shuttle to protect a clinician from needle stick injuries.

Abstract: Packaging (5) for catheter treatment devices, such as catheters (10) including multi-electrode arrays (6), are disclosed herein. In one embodiment, for example, a catheter package assembly comprises a tray (50), a lid (80), and a coiled sheath (30) disposed in the tray. The tray includes at least one pocket (54) adapted to receive a distal end portion of a catheter. The tray and lid each include cooperative latching features (90). The sheath defines a lumen that is configured to receive an elongate shaft (4) of the catheter.

Abstract: An endoscopic treatment system includes: an endoscopic treatment device having an operating unit which has a distal end and a proximal end and a sheath; and a guide wire which has a coated region applied with coating at a distal end. A packaging material has a tray which maintains a predetermined position relationship between the sheath and the guide wire and holds the distal end side of the sheath in a state where the coated region of the guide wire is exposed from the distal end of the sheath. The tray is located on the distal end side of the sheath to a sheath holding portion, which holds the sheath, and has a wire accommodating portion which holds the full length of the coated region of the guide wire exposed from the distal end of the sheath in a linear form.

Abstract: Package (10) for holding an intermittent, male urinary catheter (1). The package (10) has a vessel (5) which is tubular in shape allowing the urinary catheter (1) to be movably arranged in an inner volume of the vessel (5). An enveloping housing of the package entirely encloses the urinary catheter (1) when packaged. The enveloping housing has three tubular parts (2, 3, 6) of which a first and second straight part (2, 3) are of a hard plastic material, and a third part (6) is of a flexible material. The first straight (2) part is closed off at a bottom end thereof and the second straight part (3) is closeable by the cap (4) and comprises the vessel (5).

Abstract: A sampling device for a specimen container having a closure sealing the interior of the specimen container from the environment includes a needle, a body coupled to the needle and defining a chamber in fluid communication with the needle, the body further comprising a port forming an opening in the body, the port in fluid communication with the chamber. A multitude of the sampling devices may be stored in a cassette. The sampling devices may include a second chamber for separation and concentration of a microbial agent present in a sample. In this configuration second chamber is connected to the first chamber via a valve or the like.

Abstract: Systems and methods for treating a lung of a patient. One embodiment of a method comprises positioning a leadless marker in the lung of the patient relative to the target, and collecting position data of the marker. This method further comprises determining the location of the marker in an external reference frame outside of the patient based on the collected position data, and providing an objective output in the external reference frame that is responsive to movement of the marker. The objective output is provided at a frequency (i.e., periodicity) that results in a clinically acceptable tracking error. In addition, the objective output can also be provided at least substantially contemporaneously with collecting the position data used to determine the location of the marker.

Abstract: The present invention is a storage and protection device for bronchoscopes having a protection tube of sufficient length to enclose at least a majority of a length of an insertion tube of a flexible bronchoscope. Extending upward from a top end of the protection tube is an upper structure support clamp adapted to releasably secure an upper structure of the flexible bronchoscope so that at least a majority of the length of the insertion tube lies within the protection tube. The upper structure support clamp connection with the upper structure of the bronchoscope preferably allows the insertion tube to hang freely within the protection tube when the protection tube is oriented substantially vertically.

Abstract: Packaging for a catheter includes coiled tubing for receiving the catheter and a mounting card coupled to the coiled tubing. The windings of the coiled tubing are welded together to maintain the coiled configuration. The mounting card includes an integral support flap for reducing the risk of damage during catheter insertion and removal, an integral luer retainer for securing a catheter luer, and one or more integral tabs for attaching catheter accessories to the packaging. The integral support flap creates a contact zone which discourages grasping the packaging at a location that can potentially damage an object passing through the packaging, such as a balloon and/or stent. The integral luer retainer is configured to selectively alternate between a configuration which secures the catheter luer and configuration which allows releases the luer for easy insertion and removal of the catheter.

Abstract: A bottle rack assembly selectively supports one or more bottles. The bottle rack assembly includes a first support structure defining a first opening and a second support structure defining a second opening. The bottle rack assembly includes a support shelf that is received within the first opening of the first support structure and within the second opening of the second support structure such that the support shelf is supported between the first support structure and the second support structure. The support shelf includes a first support platform extending along a first support direction that is substantially perpendicular to a first direction and a second direction along which the first support structure and the second support structure extend. The first support platform defines a first support channel defined within a first upper surface of the first support platform.

Abstract: An injection device includes a housing 101 to 104 containing a syringe 24. The contents of the syringe 24 are viewable through a window 14 in the mid-section 102 of the housing. The window 14 is concealed by a slideable shutter 12. The slideable shutter 12 is biased by a bias spring 22 which also biases an internal syringe carrier. Also disclosed is a reversible needle cap which operates initially to cap the front end of the housing and, upon removal thereof, pulls a needle sheath 30 off the syringe needle 26. The cap is designed to be reversible so that, after use, it can be reversed and reconnected to the housing to cover the exposed needle.

Abstract: A catheter assembly includes a catheter, part of which forms an insertable length to be inserted through a body opening and a catheter receptacle to accommodate at least part of the catheter such that an insertable portion of the catheter is enclosed but part of the catheter is left outside of the receptacle. Also disclosed is a method for producing a catheter assembly which includes providing a receptacle having an opening, providing a catheter which has a catheter tube and a connector on one end thereof, arranging the catheter tube in the receptacle, and connecting the receptacle to the connector to close the opening.

Abstract: A syringe assembly including a plunger rod having a first end, a second end, and a rod portion extending therebetween, wherein at least a portion of the rod portion is flexible is disclosed. The flexible portion of the rod portion allows a stopper to be moved between a first position and a second position within a syringe barrel while the overall length of the syringe assembly remains the same throughout the movement between the first position and the second position. In another embodiment, a syringe assembly including a restraining member adapted to communicate with the flexible portion of the rod portion such that movement of the first end of the plunger rod in a first direction actuates movement of the second end of the plunger rod in a second direction different than the first direction is disclosed.

Abstract: The present invention relates to systems and methods for preparing and completing surgical and medical procedures. In particular, the invention relates to kits for improving preparation and completion time for a medical or surgical procedure in which the kit includes modularized compartments containing sterilized medical or surgical equipment and wherein the medical or surgical equipment is organized and/or ordered within the kit to generally correspond to the sequence of steps of the medical or surgical procedure. The kit is particularly applicable to recanalization procedures for stroke patients as well as revascularization procedures for acute myocardial infarction patients where a kit enables faster preparation and completion of these procedures.

Abstract: The package supports a plurality of consumable products. The package is a blister package having a plurality of consumable products housed in a blister tray and covered with a rupturable sheet. The sheet overlies the open surfaces of the blister tray and includes rupturable locations formed thereon for permitting passage of the product therethrough.

Abstract: The carrier for prefilled syringes has a body made from a dimensionally stable elastic material with a chamber for inserting the syringe. The flange of the syringe cylinder is fixed in the axial direction in a defined recess, whereas the syringe plunger is fixed in any position in an elongated recess.

Abstract: A package for a medical device having an elongated shaft and a proximal luer fitting includes a one-piece body formed as a single structure via blow molding. The blow-molded one-piece body includes at least a spiral casing formed therein, the spiral casing defining a spiral lumen configured to receive the elongated shaft of the medical device. Webbing is disposed between adjacent curved portions of the spiral casing. The one-piece body formed via blow-molding may also include a removable reversible loading tube, a luer retainer, a cannula holder, one or more slots for attaching an information card thereto, a fastener for clipping the medical device thereto, and a compartment for holding an oxygen scavenger. Further, the one-piece body formed via blow-molding may include non-circular lumens and may be configured to receive multiple medical devices.

Abstract: A catheter assembly including an elongate member having a proximal end and a distal end. The distal end has at least one drainage opening. A hydrophilic coating is provided on at least a portion of the elongate end of the catheter. A fluid containing member is provided and is either arranged on the elongate member or within a separate area of the container. The fluid containing member contains sufficient hydrating fluid to hydrate the coating of the catheter. A container contains the elongate member and the fluid containing member and incorporates at least one foil layer to prevent evaporation of the hydrating fluid. A method of using the catheter includes inserting a catheter into a user's body and draining fluid from the user's body.

Abstract: The present invention provides an assembly for the preparation of a medical device having a porous coating comprising hydrogen peroxide. Particularly interesting medical devices are catheters (such as urinary catheters), endoscopes, laryngoscopes, tubes for feeding, tubes for drainage, guide wires, condoms, urisheaths, barrier coatings e.g. for gloves, stents and other implants, extra corporeal blood conduits, membranes e.g. for dialysis, blood filters, devices for circulatory assistance, dressings for wound care, and ostomy bags. The coating is in particular a hydrophilic coating formed from cross-linked polyvinylpyrrolidone. In one embodiment, the assembly holds a dry catheter element in one compartment of a package and an aqueous hydrogen peroxide solution in another compartment. The solution may also comprise stabilizers, e.g. chelators, and osmolality increasing agents.

Abstract: A urinary catheter kit is provided. The catheter kit includes a catheter with a flared end and a package provided with interior protrusions for cooperating with the flared end of the catheter. The largest outer diameter of the flared end of the catheter is slightly larger than the smallest diameter of the package at the protrusions. Thereby, the protrusions will function as a backstop for the catheter. The rigidity of the catheter at the flared end is selected so that—depending on the angle of the flared end—the flared end will be able to flip over if it is subjected to a force over a predetermined level. Thereby the catheter will be able to be entered back into the package.

Abstract: A package system and method are provided for storing and shipping of elongated endoluminal devices. In one aspect, the system includes a packaging tray having a first area to maintain the position of a first portion of the elongated endoluminal device and a second portion retaining an opposing portion of the elongate device. The second portion configured to hold the coupling element of the assembly and being radially spaced outward from the first portion.

Abstract: A method of making a ready-to-use catheter assembly and a ready-to-use catheter are provided, which avoids any degradation of the catheter during sterilization. The method comprises: placing a catheter with a hydrophilic coating and a wetting fluid in a catheter package made of low moisture transmission material while the package is in a first condition wherein an insertable length of the hydrophilic coating of the catheter is not in contact with the wetting fluid, sterilizing the catheter package with the catheter and the wetting fluid by radiation sterilization while the catheter package is kept in a condition in which the insertable length is not in contact with the wetting fluid, transferring the catheter package with the catheter and the wetting fluid into a second condition, bringing the wetting fluid into contact with at least the insertable length and activating the insertable length via gravity and/or via inertia.

Abstract: A containment clip is provided having securement members for connection to medical device accessories such as guide wire hoops and access accessories such as needles and introducers. The containment clip can be utilized as part of a kit, secured by a hinged connection to one or more medical device accessories.

Abstract: A packaging system for medical devices includes a elongate connector having a plurality of channels formed therein, and a first and a second tubular holder configured to form an assembly with an elongate, coiled medical device. The first and second tubular holders each have shapes congruous with the plurality of channels, and are positionable therein such that the elongate connector forms a bridge attaching the tubular holders in an assembly with a medical device.

Abstract: A handling system for use in the manufacture of syringe barrels includes a tray having an array of apertures with a tubular upstand around each aperture, each upstand at the upper end thereof defining a support surface for a syringe barrel. Each syringe barrel comprises a cylindrical part and an enlargement at or adjacent the rear end of the barrel and carries at its forward end a safe needle device or a needle shield of a greater diameter than the syringe barrel. At least one of the enlargement of the syringe barrel or the support surface has a profile tapering or rounded inwardly in the downward direction so that when the tray is supported generally horizontally and a syringe barrel is lowered into an upstand, the syringe barrel is centred by co-operation between the enlargement and the support surface. The enlargement may be a flange at the rear end of the syringe barrel or could be a further component fitted to the barrel.

Abstract: Medical dispensers having cap removal feature are disclosed. An illustrative medical dispenser can include a container body having an interior chamber adapted to contain a number of unused medical instruments, and an opening mechanism on the container body for providing access to the contents within the interior chamber. A gripping element on the exterior of the container body can be used to facilitate the removal of a portion of the medical instrument.

Abstract: A medical lumen access device assembly includes a medical lumen access device holder including an elongate tube defining a lumen extending from a proximal opening of the elongate tube to a distal opening of the elongate tube. A check valve is positioned over an opening of the elongate tube and includes a valve member having a biased closed position wherein an internal volume defined by the lumen is fluidly blocked from an exterior of the elongate tube at the opening and an open position defining a fluid path from the exterior to the internal volume through the opening. The medical lumen access device assembly also includes a medical lumen access device disposed at least partially within the lumen and having a proximal segment extending beyond the distal opening. At least a portion of the medical lumen access device includes a hydrophilic coating.

Abstract: A package for pharmaceutical products, in particular for parenteral products (prefilled syringes, flacons, ampoules, vials, bottles), comprises a supporting body forming at least one compartment for containing a parenteral product made from a single-sheet blank, preferably made of paper-based material, which has a base face, an upper face and a plurality of lateral faces which are connected to the base face and/or to the upper face, said upper face having at least one opening made in it and comprising at least one foldable portion defined by cutting lines of the upper face and/or by crease lines and delimiting a portion of the opening to form a cavity designed to receive the parenteral product, the supporting body being able to switch between a non-operating condition in which it has a planar profile which minimises its dimensions, and an operating condition in which: the supporting body is substantially box-shaped; the foldable portion is folded inside the supporting body so that together with the opening it