Abstract: A pharmaceutical dispenser including a tube having an open end and a space filled with a composition, and an applicator including a first end removably coupled to the open end of the tube and a longitudinal portion with at least one aperture is described. The dispenser can also include a removable cover extending longitudinally and having a bore surrounding the longitudinal portion of the applicator. The composition may be an anal medication. A single dosage unit of the composition is usually contained in the tube, and the tube, applicator, and cover are disposable after use. Methods of using the dispenser include squeezing the tube, allowing the composition to exit the aperture of the applicator, and applying the composition to a target area.

Abstract: The device for examining moving tablets comprises a sensor element designed as a hollow body having a closed surrounding jacket of a conductive material, an open entrance side at a top and an open exit side at a bottom. The sensor element defines in its interior space a continuous path for the tablets extending from the entrance side to the exit side, and the jacket of the sensor element is grounded via a resistor. The device also comprises at least one pickup element of conductive material arranged near the outside surface of the jacket of the sensor element, the pickup element being galvanically isolated from the outside surface of the jacket of the sensor element.

Abstract: A fosfomycin plus tobramycin combination formulation for delivery by aerosolization is described. The concentrated fosfomycin tobramycin combination formulation containing an efficacious amount of fosfomycin plus tobramycin is able to inhibit susceptible bacteria. Fosfomycin and tobramycin are formulated separately in a dual ampoule such that when reconstituted, the pH is between 4.5 and 8.0 or as a dry powder. The method for treatment of respiratory tract infections by a formulation delivered as an aerosol having mass medium average diameter predominantly between 1 to 5?, produced by a jet or ultrasonic nebulizer (or equivalent) or dry powder inhaler.

Abstract: A unit designed to allow freedom to handle one and only one daily dosage of medications or vitamins. The polypropylene base embodies seven identical round holes that securely accepts one each, clear polypropylene vial. The vials hinged lid snaps shut and is easily opened with a push of ones thumb. Each vial displays one each of seven days of the week. All vials would be filled with a daily AM or PM dose of medications or vitamins. At the proper time, one simply removes the single vile from the base for that appropriate day and time. To replenish on a weekly basis, simply flip open each vial and count out the desire dosage.

Abstract: A system for diagnostic testing may include a meter for performing a diagnostic test on a sample applied to a test media, the meter having a housing and an interface for receiving a signal representing coding information, and a container configured to contain test media compatible with the meter, the container having a coding element associated therewith. Additionally, the system may provide a mechanisms for removing the meter from an interconnected test container and reattaching it to a new container using on-container coding methods that can recalibrate the meter for the new container of test strips. The system may further provide a sampling device, such as a lancet, operably connected to the container such that that a user may use the sampling device to obtain a sample without disconnecting the sampling device from the container.

Abstract: A container is disclosed for housing a tray or blister pack. The container includes a shell (40) with an internal volume for holding the tray or blister pack, and a cover (10) with a base (11), hinge (13), and lid (12) for enclosing the shell (40).

Abstract: A closure for a container having a support device for fillers, in particular a tablet tube, the support device providing an elastically deformable support element that is capable of being brought from a first position, in which the support element is undeformed, into a second position in which the support element is deformed. The support element has a contact area that, in the second position, transmits a supporting force to the fillers; in the second position the support element is situated closer to the container mid-axis than is the case in the first position.

Abstract: The present invention includes a consumer product packet comprising a capsule and a fill composition within the capsule. The capsule has a tack temperature of about 110° F. or higher and substantially dissolves in water within a predetermined time period at a temperature of about 70° F. or lower. In one example, the capsule comprises a film having at least one polymer, at least one plasticizer, and at least one temperature adjusting agent. Dependent on the fill composition, the consumer product packet may be used for any household or personal use. In one example, the fill composition is a detergent concentrate comprises one or more surfactants, one or more humectants, and a coalescing solvent which has hydrophilic-lipophilic balance (HLB) value from about 7 to about 9, wherein the ratio of the one or more humectants to the coalescing solvent is more than 1.

Abstract: A pharmaceutical formulation, comprising: a compound of formula I, a tautomer of the compound, a salt of the compound, a salt of the tautomer, or a mixture thereof, and at least one ingredient selected from the group consisting of (i) cellulose; (ii) silicon dioxide; (iii) magnesium stearate; and (iv) an ingredient selected from crospovidone, starch, or lactose.

Abstract: The invention provides a packaging material which comprises a polymeric base component and a barrier component which coats and lines a surface of the base component, the barrier component inhibiting migration of gases, vapors and liquids through the base component. The barrier component comprises a polymeric layer comprising at least two different polymeric species which are polar and which are water soluble. The different species have different chemical compositions and are complementary in that they are bound together physically by interpolymer complexation to form an interpenetrating physical network. The invention also provides a process for producing the packaging material which comprises coating at least one surface of the base component with the barrier component and causing the complementary species to interact together physically by interpolymer complexation to form an interpenetrating physical network.

Abstract: A handheld toothpaste dispensing system that dispenses single serving portions of toothpaste in preformed shapes includes an outer housing surrounding an interior chamber. To load the dispensing system, a replaceable or refillable disk containing single serving portions of toothpaste assembled in spaced arrangement is inserted into the interior chamber of the dispensing device and is supported on a disk advancing mechanism. In operation, a button on the dispensing device is pressed to operate the disk advancing mechanism, thereby advancing the disk through a partial rotational movement and exposing the subsequent compartment on the disk within a dispensing opening on the housing of the device. The preformed shapes of toothpaste are removed from the disk for brushing by inserting the bristles of the user's toothbrush into the preformed shape of toothpaste and subsequently pulling the toothbrush away from the disk with the single serving toothpaste shape clinging to the bristles.

Abstract: A process for making a detergent composition, the detergent composition comprising: a) from about 0.1% to about 50% by weight of the composition of a polymer in particulate form comprising: i) a carboxylic acid monomer; ii) more than about 5% by weight of the polymer of a sulfonic acid monomer; and iii) optionally a non-ionic monomer; and b) from about 0.01% to about 10% by weight of the composition of a hydrophilic silica. the process comprising the steps of: a) pre-mixing the polymer with the hydrophilic silica to obtain a polymer/silica premix; and b) mixing polymer/silica premix with any additional detergent components.

Abstract: The invention provides low-dose formulations of guanylate cyclase-C (“GCC”) agonist peptides and methods for their use. The formulations of the invention can be administered either alone or in combination with one or more additional therapeutic agents, preferably an inhibitor of cGMP-dependent phosphodiesterase or a laxative.

Abstract: A method of fabricating a drug-transfer device includes forming a package having a first component retaining multiple volumes of a drug and a second component retaining an agent. The first component and the second component are integrally formed together. The agent is configured to suppress a physiological effect of the drug when the agent contacts the drug or is coadministered with the drug. The method allows exterior surfaces of the first and second components to be cleanable (e.g., prior to final assembly). After such cleaning, either no or substantially no amount of drug and agent is present outside the package. According to some embodiments, the package may be fabricated such that either no or substantially no amount of the drug is present within the second component and such that either no or substantially no amount of the agent is present within the first component.

Abstract: A new package for medicine has an extended base section that has a generally planar top surface. A series of separate receptacles with frusto-conical walls are positioned across the base section. The receptacles are not integral with (or adhered to) the base section. Instead, each of the receptacles is nested in one of a series of apertures in the base section. Each receptacle has a flange that extends outwardly from and surrounds the opening on the receptacle. The flange has a top surface that is wider than the aperture in which the receptacle is nested, preventing the receptacle from falling through the aperture. A flexible, removable top sheet is sealed to a part of the top surface of the base section, sealing the medicine within the walls of the receptacles and preventing the receptacles from being lifted out of the aperture until the top sheet is peeled back. The top sheet may be adhered to the base section along lines of adhesion that surround each of the openings.

Abstract: A blister card package structure with increased support comprising a first card having an inner surface and an outer surface, the first card defining an outer edge, a second card having an inner surface and an outer surface, the second card defining an opening therein and an outer edge, a blister having a body portion and a flange, wherein the body portion extends through the opening in the second card, and wherein the flange is positioned between the inner surfaces of the first and second cards, and an inner frame stiffener positioned between the inner surfaces of the first and second cards, wherein the inner surface of the first card is sealingly connected to the inner surface of the second card along the outer edges of the first and second cards.

Abstract: A dispensing system (300) includes a packaging structure (200) and a blank (100) that is constructed to enclose the packaging structure (200). The dispensing system (300) includes a top panel (110) and a bottom panel (112) that define a tubular structure (310) and includes side flaps (120a, 120b) that are configured to extend into the tubular structure (310). The side flaps (120a, 120b) close the open sides of the tubular structure (310).

Abstract: A child-resistant package includes a case and blister cards. The blister cards are mounted for movement between stored positions inside the case and exposed positions outside the case.

Abstract: The present invention provides a package assembly for enclosing and dispensing a plurality of consumable products. The package assembly includes a package housing defining a pair of product pockets each having an open end for removably accommodating a plurality of products in an aligned array. The open ends of the pockets are in facing orientation. The package housing includes a fold line between the open ends of the pocket for folding the housing thereat and placing the pockets in an angled orientation for dispensing of product. The housing further defines at least one openable flap for overlying and enclosing the pockets.

Abstract: Disclosed is a medication dispensing system comprising a container including at least two compartments each compartment including a cavity configured to contain at least one first medication, a covering over the cavity configured to break under pressure, and an elongate conductive element on at least a portion of the covering and configured sever upon breaking the covering. The medication dispensing system further includes one interrogator-readable RFID circuit operatively associated with the container and connected to the elongate conductive element of each of the at least two compartments, and one RFID circuit interrogator configured to interrogate the one RFID circuit and determine whether the elongate conductive element is severed on either on at least one of the at least two compartments.

Abstract: A child-resistant medicate container includes a housing having a top segment fixedly attached to and extending from a bottom segment. Each of the bottom segment and the top segment include a generally flat first sidewall and an opposing generally flat second sidewall that define the storage cavity. Each sidewall defines a plane and each plane extends generally parallel with respect to the remaining planes. The planes defined by the first and second sidewalls of the bottom segment are spaced-apart a greater distance than a distance between the planes defined by the first and second sidewalls of the top segment. A cover is movably attached to the housing and surrounds at least a portion of the first and second sidewalls of the top segment of the housing. One of the cover and the top segment of the housing include an aperture formed in a sidewall thereof.

Abstract: A blister package and method of removing a dosage form from a blister package are disclosed. In one embodiment, the blister package includes a unitary blister sheet and a unitary sheet of lidding material. The lidding sheet is peelably sealed to the blister sheet, and includes unsealed areas for facilitating the peeling of the lidding material from the blister sheet. The unsealed areas are preferably only accessible upon a bending of the blister package.

Abstract: A pharmaceutical package and an associated method are provided that is child resistant, but that may be readily accessible for users having arthritis or otherwise having limited mobility in their fingers. The pharmaceutical package includes a housing and a card carrying medication that is slidably disposed at least partially within the housing such that the at least one medication is positioned within the housing. The pharmaceutical package also includes an engagement member configured to engage the card in an instance in which the card is disposed within the housing. For example, the card may define an opening and the engagement member may be configured to extend into the opening defined by the card when the card is in the housing. The pharmaceutical package also includes a twistable actuator configured to disengage the card and the engagement member in response to rotation of the twistable actuator relative to the housing.

Abstract: The invention relates to compounds, methods, uses, compositions, combinations, kits and packages for the prevention and/or treatment of parasite infection (e.g., Plasmodium parasites) and/or disease (e.g., malaria) based on uses of (a) cystamine, cysteamine, and analogs, derivatives, prodrugs, precursors thereof; an agent capable of inducing their production; and/or salts thereof, and (b) artemisinin and functional derivative, analog, conjugate, metabolite, prodrug or precursor thereof, and/or salts thereof.

Abstract: A method and system provides a stored value token that includes a three dimensional, closed volume which can include a movable cover for allowing access to the closed volume. The closed volume can contain various movable objects such as consumer goods, like plant seeds, edible food stuffs like mints, and/or utilitarian objects that can be used by the consumer such as screws, nails, nuts, bolts, etc. The closed volume can comprise human readable printed media on one side that identifies the volume as a stored value card and that identifies the contents being contained within the closed volume.

Abstract: A package for a capsule medical device includes dome-shaped parts provided at two ends, a body locating between the two ends, and a plurality of retainers that are arranged at predetermined intervals so that a space in which the body of the capsule medical device is exposed to allow a grasp is formed and retain the body of the capsule medical device in a manner of allowing the capsule medical device to be taken out from the package.

Abstract: A medication storage lock box that can be easily opened in an emergency includes a storage chamber to which a lid is hingeably connected. A severable strap couples the lid to a clasp that engages the locking mechanism of a combination lock. The lid may be opened either by entering the proper lock combination and releasing the clasp or, in a medical emergency caused by the owner becoming incapacitated or forgetting the combination of the lock, by cutting the strap which couples the lid to the clasp. The lock box may be made of materials such as leather, imitation leather, fiberboard-reinforced fabric, fiberboard, thermoplastic resins, thermosetting resins, or resin impregnated paper.

Abstract: The present invention relates to Rifaximin polymorphic, salt, hydrate, and amorphous forms, to their use in medicinal preparations and to therapeutic methods using them.

Abstract: A blank (10) for forming a secondary package without a heat-seal process is disclosed. The secondary package can be an inner slide card configured to receive one or more blister packs (51). A pocket opening (30) can be formed in one panel (14) of the blank (10). Receiving portions (44) can be formed on one or more panels. A blister pack (51) can be inserted into the secondary package through the pocket opening (30). The receiving portions (44) can mechanically interact with edges (56) of a blister pack (51) to retain the blister pack (51) in a desired position. The exit regions of an inserted blister pack (51) can be aligned with gates (40) formed in a panel (12) of the secondary package. When the blister pack (51) is in the proper orientation relative to the secondary package, the blister pack (51) can be locked in place mechanically, glued in place, or both.

Abstract: The invention provides a dispensing container including an outer casing having an open end, a top, a bottom, sidewalls extending between the top and bottom, and an interior compartment, wherein the outer casing further includes a depressible button in the top or bottom and at least one projection adjacent to the depressible button that extends into the interior compartment; and an inner tray slidably received within the interior compartment of the outer casing. The inner tray includes a first end received within the outer casing, an opposing second end extending outwardly from the outer casing, a flexible locking tab positioned proximal to the first end, and an opening adjacent to the flexible locking tab, the flexible locking tab including a first segment extending toward the second end of the inner tray and a second segment extending transversely from the first segment. The second segment is positioned to engage the projection.

Abstract: A child resistant product package includes a first panel, a second panel, a tab strip insert, and a blister package. The first panel incorporates at least one blister aperture and at least one tab strip access pad. The second panel includes at least one product access aperture and at least one tab strip grasping pad. The tab strip insert has at least one tab strip. The first panel and the second panel are fastened together. Once fastened together, the first panel and the second panel collectively form a housing for the tab strip insert and the blister package.

Abstract: A blister package is provided for retaining individual product units. The blister package is formed by a receptacle substrate and an outer laminate. The receptacle substrate includes a sealing flange and one or more receptacle hollows for retaining product therein. The outer laminate includes a first layer covering a sealing layer, with the sealing layer bonded to the receptacle flange and covering the product within the hollows. A repeating score line pattern is formed in the outer laminate for promoting a tear in the laminate upon forcing the product from the receptacle hollow against the outer laminate. The score pattern extends substantially across the area of the outer laminate covering the receptacle hollow and includes a plurality of spaced score lines formed in a crosswise relationship.

Abstract: The present invention relates to assisting patients in the taking of medication, and to assisting third parties in accumulating information regarding patient medication intake. The invention may be embodied a system including a portable medication monitor used in association with an instrumented medication package to provide intake data acquisition and patient support functions. The system may further be connected to a computer or computer network allowing information distribution between the medication monitor and third parties, such as physicians or pharmacists.

Abstract: A child-resistant package includes a case and blister cards. The blister cards are mounted for movement between stored positions inside the case and exposed positions outside the case.

Abstract: A package has a package body formed by mating film materials and sealing peripheral edge portions of the mated film materials so as to form a content accommodation compartment inside the sealed peripheral edge portions, the sealed peripheral edge portions being subjected to an easily peel-off treatment so that the sealed peripheral edge portions are separated and peeled off from each other when the package is opened. A seal opening starting portion is formed outside of one of the sealed peripheral edge portions so that the film materials are separated from each other at the seal opening starting portion, and at least one projection is provided on at least one of inner and outer side surfaces of the film materials forming the seal opening starting portion.

Abstract: A dual compartment dispenser for pill or other item storage includes a larger outer compartment and an auxiliary smaller pocket container configured to accommodate a predetermined daily dosage of items, which the user can carry in a clothing pocket, backpack or handbag, without having to carry the entire bottle container of items. The smaller auxiliary pocket container compartment fits on top of or underneath the cap of the item container compartment, and is held in place by being threaded to the top of the cap of the container, or to an underside of the cap of the container. The smaller auxiliary pocket container compartment can also be held in place by a friction fit or magnetic attachment within or on top of the outer container, with or without a detent and/or ledge supporting the smaller auxiliary pocket container compartment. It can also be loosely supported by a ledge within the neck of a bottle neck container.

Abstract: The invention relates to a case for receiving a blister pack, comprising a first case half and a second case half. The halves are hinged on one another. The first case half is designed as a pocket for receiving the blister pack and has an outer part and an inner viewing part and also first apertures in the viewing part and second apertures in the outer part. The first apertures are at least partially aligned with the second apertures, specifically at least where the receptacles are located after the blister pack is received in the pocket. The second case half has a first compartment for receiving a first display displaying days of the week, and first windows for displaying the days of the week in an inner viewing surface of the second case half in the area of the first compartment. The first windows are arranged in such a way that they are aligned with the columns of the receptacles of a medicament pack received in the pocket.

Abstract: A medicament dispenser comprises a housing having opposing first and second walls. A connecting assembly is associated with at least one of the first and second walls to facilitate connection of the first and second walls to one another. A blister pack containing the medicament is pivotally connected to the connecting assembly so as to be rotatable about the connecting assembly and about an axis of rotation substantially orthogonal to the first and second walls to facilitate movement of the blister pack from: i) a closed position in which the blister pack is substantially enclosed within the housing; and ii) an open position in which the blister pack is at least partially rotated from the housing.

Abstract: Containers and methods for disposing unused pharmaceutical product are disclosed. Each container (100, 200, 300) may include a container body (104, 204, 304) with an internal chamber (116, 216, 316) for storing pharmaceutical product, along with a cover (124, 224, 324) for selectively limiting access to the chamber (116, 216, 316). An encapsulation component (128, 228, 328) may be selectively disposable within the chamber (116, 216, 316), and may be operable to encapsulate the pharmaceutical product within the container (100, 200, 300). For instance, the encapsulation component (128, 228, 328) may melt and/or flow into contact with the pharmaceutical product and thereafter solidify to encapsulate the pharmaceutical product. The encapsulation component (128, 228, 328) may melt and thereafter solidify between the cover (124, 224, 324) and shell (104, 204, 304) to limit removal of the cover (124, 224, 324) from the shell (104, 204, 304).

Abstract: A locking medicine bag is disclosed that includes a casing having an exterior surface and an interior surface. There is a zipper disposed on at least one side of the casing having a zipper slider connected to first and second half zipper tracks. A zipper handle is connected to the zipper slider, and the zipper handle includes a hook member extending from one side of the zipper handle. The zipper handle and hook member are a single molded piece. Further, there is a combination lock secured along one side of the casing. The combination lock includes an exterior plate having a slot that exposes a latch member. The slot is sized to receive the hook member of the zipper handle, and the hook member engages the latch member in a locked configuration.

Abstract: A package set is provided. The package set includes a holder; a container removably coupled to the holder; and a correlator including at least one container label coupled to the container and at least one holder label coupled to the holder, each container label and each holder label includes a description portion and an indicator, the indicator of the holder label is substantially identical to the indicator of the container label to facilitate matching at least one container to at least one holder.

Abstract: A method of manufacturing a film (6) includes the following steps: a) a film-forming mixture containing at least one film-forming agent is prepared; b) a dose of the mixture is deposited in a cell (4) of a cellular substrate (2), the mixture having a viscosity ranging from 1 to 8000 mPa·s at the temperature of the film-forming mixture during the deposition; c) the mixture is cured so as to obtain a film (6); and d) the cell (4) is closed off by a hermetic sealing element (3). A device (1) especially suitable for the method and a device intended to implement the method are also described.

Abstract: An example embodiment is a medication container. The container includes a body and cap. The cap is configured to rotatably engage the body, with the cap and body defining a cavity for storing medication when engaged. A locking pin is configured to prevent the cap and body from disengaging without application of a twisting force about the cap and body. In a particular arrangement, a key carrier for retaining a key placed therein is coupled to the body.

Abstract: A case for receiving and dispensing pills, having an optional top cover having a forward edge and a rearward edge, an optional bottom cover having a forward edge and a rearward edge, a spine extending between the top cover and the bottom cover, to which the top cover and the bottom cover are affixed at the rearward edges thereof, and at least one sleeve containing a plurality of pills secured within the sleeve and adapted to be dispensed therefrom, the sleeve having a forward edge and a rearward edge and being attached to the spine at the rearward edge thereof between the top cover and the bottom cover.

Abstract: A package is provided that is able to contain tablets or like separate dispensable items in a manner exhibiting child-resistant and senior-friendly dispensing properties. The package includes a card, such as a blister card, and a protective hollow sleeve. The card has a base strip on which a plurality of spaced-apart compartments are provided for holding the tablets or like items, and the sleeve has an opposed pair of side edges extending between opposite ends with at least one of the ends being a dispensing end of the package. The sleeve provides a protective housing for the card when the card is in a storage position within the sleeve, and the card is slidable relative to the sleeve between the storage position and a dispensing position in which the card extends at least partially outside the sleeve to expose at least one of the compartments.

Abstract: A medicament dispenser can include a first side surface, a second side surface spaced from and substantially opposed to the first side surface, and a medicament packaging structure located between the first side surface and second side surface. A pivot structure can extend between the first side surface and the second side surface, and the medicament packaging structure can be rotatable about the pivot structure. Thus, the medicament packaging structure can be rotated from an enclosed state in which the medicament packaging structure is substantially enclosed by the first side surface and/or second side surface, to an exposed state in which the medicament packaging structure is substantially exposed from at least one of the first side surface and/or second side surface to provide user access to the medicament(s) stored in the medicament packaging structure.

Abstract: A storage component for a storage system generally includes at least one or more microcapsules applied to the storage component. The at least one or more microcapsules include an aromatic encapsulate configured to release a fragrance and/or chemical to thereby associate the fragrance and/or chemical with the storage component. And, a method for associating a fragrance and/or chemical with a storage component generally includes encapsulating at least one or more desired fragrances and/or chemicals in multiple microcapsules, and coating at least part of a storage component with the microcapsules. The encapsulated fragrances and/or chemicals are configured to be released from the microcapsules to thereby associate the fragrances and/or chemicals with the storage component.

Abstract: A storage unit is provided for removably storing an in vivo imaging capsule. The capsule may have a housing and an optical dome. The storage unit may include a recessed space formed for accepting the capsule. A magnet for magnetically activating and deactivating the capsule may be provided in the storage unit, for example in the lid. The storage unit may also include a capsule holding unit comprising at least two protruding elements to removably hold the capsule in the storage unit, wherein the protruding elements are positioned to grip the capsule housing.

Abstract: A blister package is provided in which the lidding component includes a tear-resistant nonwoven layer and a barrier layer wherein the controlled delamination of the nonwoven layer increases the puncture resistance, thereby improving the child-resistant properties of the package.

Abstract: A container comprising a closure means coated by an inert fluorinated material and containing a liquid pharmaceutical composition. In particular, the container comprises a closure means coated by TEFLON (polytetrafluoruethylene (PTFE)) and contains a HSA-free Interferon-? formulation having the following composition: 30 to 100 ?g/ml of interferon-?, an isotonicity agent, 0.1 to 2 mg/ml of Poloxamer 188, at least 0.12 mg/ml of L-Methionine and a buffer solution capable of maintaining the pH of the liquid formulation at a value between 3.0 and 4.0.