Abstract: Apparatus and methods for separating a fluid, with the apparatus including an inner drum wall disposed around and coupled to a shaft. The apparatus also includes an outer drum wall disposed around the inner drum wall, the outer drum wall being configured to rotate to separate a higher-density component of the fluid from a lower-density component of the fluid. The apparatus further includes a first radial vane disposed between the inner drum wall and the outer drum wall and having first contours configured to turn the fluid in at least one of a radially-inward direction and a radially-outward direction. The apparatus also includes a housing at least partially surrounding the outer drum wall and configured to receive the high-density component of the fluid therefrom.

Abstract: A centrifugal bowl (105) comprises a base (3) that can rotate about an axis of rotation. A filter sieve in the shape of a perforated peripheral side sieve wall (151) extends from an open end to the base, and a plurality of vanes (155a . . . 155f) is disposed in a predominantly radial direction on the inner surface of the perforated peripheral side sieve wall (151).

Abstract: Disclosed is an apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at various fractions in the apparatus. A buoy system that may include a first buoy portion and a second member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient. Also selected fractions from the sample can be applied to a patient, either alone or as part of a mixture.

Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at various fractions in the apparatus. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient. Also selected fractions from the sample can be applied to a patient, either alone or as part of a mixture.

Abstract: A method for treating an organic waste, in which the organic waste is pressurized and continuously supplied to a high temperature and pressure treatment apparatus to produce a slurried material by blowing steam into the organic waste to cause a reaction while heating, pressurizing and agitating. The slurried material is dehydrated to produce a separated liquid product and a separated solid product. The separated solid product includes sufficient combustible content to produce a fuel product. The separated liquid product is purified.

Abstract: Extracting or removing at least a portion of liquid phase from a whole sample using a centrifugal force is disclosed. Centrifugal forces are used to apply pressure to a whole sample and drive a liquid phase through a passage region that can be perforated and/or porous and maintain a drier portion within a separation container. The whole sample can be dried, which includes a remaining sample where excess or a selected amount of liquid is removed. Direct access to the separation container or area can then be made to provide for an efficient withdrawal of the drier material from the separation container.

Abstract: The present invention relates to separating one or more of sand and other particulate matter from a mixture of animal waste and water. The present invention can help to control the discharge of noxious odors while processing material containing animal waste. An exemplary apparatus in accordance with the present invention includes a cylindrical housing and a non-rotating collection table. An exemplary apparatus in accordance with the present invention includes optional shield provided inside the cylindrical housing that can help to capture the particulate matter and that can also help to reduce the discharge of noxious gas and odors from the apparatus.

Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.

Abstract: A method and apparatus can separate and concentrate a selected component from a multi-component material. The multi-component material may include a whole sample such as adipose tissue, whole blood, or the like. The apparatus generally includes a moveable piston positioned within a separation container and a withdrawal tube that is operable to interact with a distal end of the collection container past the piston. Material can be withdrawn through the withdrawal tube.

Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.

Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.

Abstract: The filter apparatus for an incoming liquid which includes a retentate and a permeate includes a housing with a frame and a hollow drum assembly mounted for rotation within the housing. An inlet assembly delivers the incoming liquid under pressure to the drum assembly. A filter assembly is mounted to the inside of the drum. A trough assembly is mounted so as to be in a fluid-tight relationship to the interior surface of the filter assembly as the drum rotates past the trough assembly. A manifold is fixedly mounted and configured to cover successive columns of openings of the drum wall as the drum rotates. Pressurized gas is directed to the manifold, so that as the drum turns, and retentate is collected on the interior surface of the filter, pressurized fluid from the manifold dislodges the retentate into the trough and out an outlet assembly.

Abstract: A centrifugal processing bag, system and method for separating the components of a mixed material is presented. The processing bag includes a hub and a first port for receiving the mixed material, where the first port includes an outlet positioned within the processing bag at a perimeter of the bag. The processing bag also including a second port having a second port inlet spaced proximate the hub and away from a central axis of the hub. The second port directs a separated material collected from the second port inlet out of the processing bag.

Abstract: Container to be used for preparing a multi-layered blood product by centrifugation, said container comprising a substantially cylindrical body (2) with a closed bottom (3) and a top (4) having a filling opening as well as a filter device (15), which is slidable inside the container (1). The filing opening is closed by means of a penetrable membrane (13), and the filter device (15) comprises a substantially planar mesh (16) and a supporting buoyancy body (18). In addition to this, there are means (35, 36, 39, 40, 42), for releasable fixation of the filter device (15) adjacent to the bottom (3) of the container (1).

Abstract: A centrifuge operative in successive low speed and high speed modes serves to remove surface cooking oil from a continuous stream of fragile snack food products wherein the oil removal occurs in the high speed mode and products are discharged from the centrifuge with relatively low kinetic energy in the low speed mode.

Abstract: A rotating separator has a housing preventing separated liquid carryover. A plenum between the annular rotating separating filter element and the housing sidewall has one or more flow path separating guides minimizing the flow of separated liquid to the outlet. The flow path guides may include one or more fins and/or swirl flow dampers and/or a configured surface.

Abstract: Disclosed herein is an apparatus and method for continuously producing and dehydrating gas hydrates. The apparatus includes a gas source, a water source, a reactor, a spinning wheel, and a centrifugal separator. The gas source and the water source are connected to the reactor. Gas and water are respectively supplied from the gas source and the water source into the reactor and react with each other in the reactor to form gas hydrate slurry. The spinning wheel and the centrifugal separator are provided in the reactor. The spinning wheel supplies the formed gas hydrate slurry to the centrifugal separator. The centrifugal separator dehydrates the gas hydrate slurry. Water removed from the gas hydrate slurry by the dehydration of the centrifugal separator is re-supplied into the reactor.

Abstract: An appliance for washing objects is disclosed that effectively and energy-efficiently filters oil-based residue from a fluid such as washing fluid that drains from a basin in the appliance. In one illustrative embodiment, an appliance includes a novel filter assembly for filtering oil-based residue out of the washing fluid. The filter assembly includes a filter layer composed of a material that is both oleophilic and hydrophobic. The filter assembly forms part of a fluid distribution system that has different configurations. A first configuration allows for recirculating filtered wash fluid from an outlet of the filter assembly back into the basin of the appliance. A second configuration allows for draining both the washing fluid from the outlet of the filter assembly and the oil-based residue from a bypass zone of the filter assembly to an appliance outlet.

Abstract: Filtration device suited for concentration of liquid samples, particularly biomolecules, and a method of concentrating, desalting, purifying and/or fractionating liquid samples. In certain embodiments the device includes a housing having a sample reservoir, and two substantially vertically oriented and spaced apart membranes disposed in the housing. An underdrain is associated with each membrane such that fluid passing through each membrane flows through a respective underdrain into a filtrate collection chamber. The fluid that does not pass through the membrane is collected in the retentate collection chamber, and can be recovered such as by a reverse spinning step, achieving recoveries greater than about 90%. The substantially vertical orientation of the membranes increases the available membrane area by at least 2.7 times the area available in a conventional filter device.

Abstract: Disclosed is a system to separate, enrich, and/or purify a cellular population from a biological tissue, such as a tissue sample. For example, an adipose tissue sample can be acquired and disrupted. The disrupted tissue sample can then be separated and purified. The separated components can include multipotent, pluripotent, or other cell populations.

Abstract: A centrifugal dehydrating device includes a bucket receiving a cylinder for receiving a mop. A shaft is mounted to a bottom of the cylinder. An annular sleeve is formed on the bottom of the cylinder and engaged with an annular fender on a mounting plate. A water fender includes a skirt having a top portion with an annular groove for receiving a rim of the cylinder. An annular wing extends radially inward from the top portion of the skirt. Water splashing upward from the cylinder during rotation of the cylinder is stopped by the annular wing. A top seat is fixed to a bottom side of the mounting plate and receives a gear train. The gear train meshes with and is driven by a rack on a pedal such that stepping of the pedal causes rotation of the gear train, the shaft, and the cylinder.

Abstract: The present invention relates to separating one or more of sand and other particulate matter from a mixture of animal waste and water. The present invention can help to control the discharge of noxious odors while processing material containing animal waste. An exemplary apparatus in accordance with the present invention includes a cylindrical housing and a non-rotating collection table. An exemplary apparatus in accordance with the present invention includes optional shield provided inside the cylindrical housing that can help to capture the particulate matter and that can also help to reduce the discharge of noxious gas and odors from the apparatus.

Abstract: A screen assembly for a shale shaker comprising a panel (500) and a support structure (600), the panel (500) having an area provided with a multiplicity of apertures and at least one layer of screening material arranged over the multiplicity of apertures, wherein said panel (500) is removable from said support structure (600).

Abstract: A fluid handling assembly is for a fluid machine that includes a casing and a shaft disposed within the casing so as to be rotatable about a central axis. An impeller is mounted on the shaft and has an inlet and a rotary separator is mounted on the shaft and has axially spaced apart inlet and outlet ends and an interior separation chamber. The separator is coupled with the impeller such that the separator and the impeller generally rotate as a single unit about the shaft axis and fluid within the separation chamber flows from the separator outlet end directly into the impeller inlet. Preferably, the separator includes a plurality of generally radially-extending blades disposed proximal to the separator inlet end and spaced circumferentially about the axis, the plurality of blades being configured to accelerate fluid flowing into the separator inlet end during rotation of the separator.

Abstract: A horizontal centrifugal scroll screen apparatus including: a housing; a frusto-conical screen assembly mounted within the housing and having an outer inlet end and an inner discharge end, the screen assembly being mounted for driven rotation via a base-of-spoke piece disposed across the inner discharge end thereof; and a frusto-conical scroll assembly coaxially mounted for differential driven rotation within the screen assembly and including an outer closed end in the proximity of the outer inlet end of the screen assembly and being adapted to direct material to be screened from a material supply conduit to the outer inlet end of the screen assembly for screening and conveyance to an outlet provided in the base-of-spoke piece.

Abstract: A centrifuge (2) for separating solids from liquid of a slurry with a conveyor (12) having a hub (14) rotatable about an axis (34) and at a helical blade (16) extending axially and radially from the hub. A bowl (4) including a cylindrical section (6) extending from an upstream end of the conveyor and a conically diverging screen section (10) extending to a downstream end of the conveyor extends about the conveyor and is rotatable about the axis. The conically diverging screen section includes an angle (40) that reduces the coefficient of friction of the solids to allow a cake formed of the solids to slide in a controlled manner forward on the conically diverging screen section with minimal back pressure, but without allowing the solid cake to break loose from the conically diverging screen section and slide out of the centrifuge in an uncontrolled manner.

Abstract: A mop strainer has a bucket, a driving unit, a transmission unit and a draining unit. The driving unit and the transmission unit are received in a pedal mount of the mop strainer. The driving unit and the transmission unit are driven by stepping on the driving unit, so as to rotate the draining unit and drain a mop. The driving unit has a reinforced sector wall and a limit slot to limit the stroke in operation. The draining unit has a water guard to prevent drained water from sputtering out and the water guard further has a mop gripper for holding the mop. Given all these features, the present invention is more robust and can be operated and stored more conveniently and practically.

Abstract: A system and method for filtering solvent including a housing for receiving the solvent and a filtering media, where the solvent is moved through the filtering media without using a pump.

Abstract: The invention relates to an outer support basket of the centrifuge basket of a screen centrifuge, wherein screen segments can be secured by conical means in the support basket, the support basket has a plurality of concentric support rings with a rectangular cross section with greater width than thickness and the broad sides of the rings lie parallel to one another and at right angles to the basket axis, wherein the support rings are spaced apart from one another by axially parallel rods which run through the support rings.

Abstract: A coolant filtration system and method for use with one or more metal working machines. The system includes a housing, pump, conveyer assembly, drum assembly, and centrifugal separator. The housing includes a tank that receives and holds coolant coming out of the one or more metal working machines. The pump is used to drive the coolant through the coolant filtration system. A part of the conveyer assembly is disposed within the housing in order to carry-away workpiece chips from the coolant. The drum assembly is located near the conveyer assembly in order to filter the coolant. The centrifugal separator receives coolant processed by the conveyor and drum assemblies. The system can further include one or more fine filters for additional filtering of the coolant outputted by the centrifugal separator.

Abstract: A centrifugal force-based microfluidic device in which a sample including particles and a fluid is centrifugally separated such that the separated fluid is quantitatively distributed, and a microfluidic system including the centrifugal force-based microfluidic device are provided. The centrifugal force-based microfluidic device includes a microfluidic structure in which, within a rotatable disc-shaped platform, a sample, including particles and a fluid, is quickly centrifugally separated into the particles and the fluid using the rotation of the disc-shaped platform and the fluid having a certain volume of the separated fluid is discharged by rotation of the disc-shaped platform.

Abstract: The separator screen arrangement of a centrifugal basket assembly reduces separator screen wear and eases structural replacement of worn parts. The centrifugal basket assembly comprises a screen-supporting basket; a separator screen, and a series of J-shaped dam segments. The separator screen is received and supported by the basket and comprises and inlet and a circular outlet end. The dam segments each comprise a dam portion, and a rim seat portion. The rim seat portions seat upon the rim, being attached thereto in a circular manner side-by-side such that the dam portions extend toward the inlet end. The dam portions dam material directed thereagainst from the inlet end so as to uniformly spread and layer material upon the separator screen before the material exits the basket assembly. The uniformly spread and layered material reduces wear of the separator screen. Material-drying and screen-protecting methodology is further supported by the basket assembly.

Abstract: A device for isolating a component of a multi-component composition. The device includes a housing, a chamber, and a withdrawal port. The chamber is rotatably mounted within the housing. The chamber includes a chamber base and a sidewall. The side wall extends from the chamber base. At least a portion of the sidewall is defined by a filter that permits passage of a first component of the multi-component composition out of the chamber through the filter and to the housing base. The filter restricts passage of a second component of the multi-component composition through the filter. The withdrawal port extends from a position proximate to the housing base to an exterior of the device. The withdrawal port permits the withdrawal of the first component from the housing base to an exterior of the device.

Abstract: The invention relates to an apparatus for preparing foods, aimed at creating fruit and/or vegetable juice from whole or chopped fruits and/or vegetables, by grating and centrifugation, including in particular: a grating disc; a basket connected to the grating disc, linked to a drive shaft, comprising in particular a filter ring and a hub; a cover, fitted with a food introduction conduit, the conduit substantially having the shape of a cylindrical tube with a circular, oval or oblong base. The purpose of the invention is to offer improvements enabling juice to be produced with a high throughput. These improvements consist in particular of an introduction conduit comprising an element for holding foods and a grating disc inclined with respect to its rotation axis.

Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.

Abstract: An apparatus is disclosed that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.

Abstract: A mixture of single-walled carbon nanotubes (“SWNTs”) is separated into fractions of enriched chirality by preparing an aqueous suspension of a mixture of SWNTs and a surfactant, injecting a portion of the suspension on a column of separation medium having a density gradient, and centrifuging the column. In some embodiments, salt is added prior to centrifugation. In other embodiments, the centrifugation is performed at a temperature below room temperature. Fractions separate as colored bands in the column. The diameter of the separated SWNTs decreases with increasing density along the gradient of the column. The colored bands can be withdrawn separately from the column.

Abstract: The PRP separator-concentrator of this invention is suitable for office use or emergency use for trauma victims. The PRP separator comprises a motorized centrifugal separation assembly, and a concentrator assembly. The centrifugal separator assembly comprises a centrifugal drum separator that includes an erythrocyte capture module and a motor having a drive axis connected to the centrifugal drum separator. The concentrator assembly comprises a water-removal module for preparing PRP concentrate. The centrifugal drum separator has an erythrocyte trap. The water removal module can be a syringe device with water absorbing beads or it can be a pump-hollow fiber cartridge assembly. The hollow fibers are membranes with pores that allow the flow of water through the fiber membrane while excluding flow of clotting factors useful for sealing and adhering tissue and growth factors helpful for healing while avoiding activation of platelets and disruption of any trace erythrocytes present in the PRP.

Abstract: A method for separating and enriching isotopes in an efficient and low-cost manner from a condensation-system (liquid or/and solid) material including two or more different isotopes by taking advantage of the sedimentation of atoms through an acceleration field by ultra-high speed rotation. The condensation-system material is placed in a sedimentation tank which is then housed in a supercentrifuge. The supercentrifuge in its rotor is rotation driven by an ultra-high speed rotation power source, and an acceleration field of energy of 100000 G to 1500000 G, i.e., about 100 to 800 m/s in terms of peripheral velocity, is applied to the above condensed (liquid or/and solid) material under such a temperature that is specified by an isotope material to be enriched. In this case, a difference in centrifugal force applied is provided between the isotopes in the condensed (liquid or/and solid) material comprising the at least two isotopes.

Abstract: Disclosed is a separator-concentrator, such as for separating and concentrating platelet-rich-plasma (PRP) from whole blood that is suitable for office use or emergency use for trauma victims. The PRP separator comprises a motorized centrifugal separation assembly and a concentrator assembly. The centrifugal separation assembly comprises a centrifugal drum separator and a motor having a drive axis connected to the centrifugal drum separator. The concentrator assembly comprises a water-removal module for preparing PRP concentrate.

Abstract: A centrifugal water separator for mop includes a bucket, a separating device and a drive device respectively mounted in the bucket. A first room, a second room and a third room respectively defined in the bucket, wherein an L-shaped partition is formed in the bucket to separate the third room from the first room and the second room, and the first room laterally communicates with the second room. The separating device includes an axle perpendicularly extending through the partition and a separating trough securely mounted to an upper end of the axle. The drive device includes a pedal mounted thereon for driving the axle with the separating trough when being stepped. The drive device includes a planet gear set sleeved on the axle and connected to the pedal for effectively drive the axle and used as a speed increaser.

Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at various fractions in the apparatus. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient. Also selected fractions from the sample can be applied to a patient, either alone or as part of a mixture.

Abstract: A drum is for a rotary separator including a shaft rotatable about a central axis. The drum includes an inner drum member having inner and outer circumferential surfaces and being disposed generally about the shaft such that a first flow passage is generally defined between the inner drum member inner surface and the shaft. The inner drum inner surface is configured to separate liquids from a fluid flow contacting the surface. An outer drum member has inner and outer circumferential surfaces and is disposed generally about the inner drum member such that a second flow passage is generally defined between the outer drum member inner surface and the inner drum member outer surface, the second flow passage being generally coaxial with the first flow passage. Further, the outer drum inner surface is also configured to separate liquids from a fluid flow contacting the surface.

Abstract: A bag loader for loading and unloading at least one satellite bag into and from the central compartment of a rotor of an apparatus for separating a composite liquid into at least two components comprises an upper part for removably securing an upper portion of at least one satellite bag; a lower part comprising a receptacle; and an intermediate part connecting the upper part to the lower part and exposing an intermediate portion of a satellite bag.

Abstract: In treatment equipment of organic waste provided with a high temperature and pressure treatment apparatus to produce a slurried material by conducting the high temperature and high pressure treatment of the organic waste, a dehydration treatment apparatus to recover the dehydrated solid matter by conducting the dehydration treatment of the slurried material and a water treatment apparatus to conduct the purification treatment of a separated liquid separated by the dehydration treatment apparatus, the treatment equipment of organic waste is characterized by having a crusher to crush said organic waste before conducting the high pressure and temperature treatment and providing to said high temperature and pressure treatment apparatus a steam blowing means to blow steam into the organic waste in said high temperature and pressure treatment apparatus, wherein said high temperature and pressure treatment apparatus is formed as a continuous reaction tank to which the organic waste is continuously supplied and to wh

Abstract: A centrifuge includes a rotational mechanism, a housing, a rotating feed pipe and a basket. The housing includes at least one side and defines an interior volume. The basket is positioned in the interior volume of the housing and is operatively coupled to the rotational mechanism such that rotation of the rotational mechanism is imparted to the basket. The rotating feed pipe extends into the basket through a pipe support positioned over the basket. The rotating feed pipe includes a nozzle operable to direct a flow of liquids, solids or combinations thereof onto a sidewall of the basket. The rotating feed pipe is operable to rotate from a first position towards a second position thereby increasing the distance between the nozzle and the sidewall and varying an angular orientation of the nozzle with respect to a normal to the sidewall.

Abstract: Simultaneous source-sink flow, or radial counterflow, is driven by a centrifugal pump disposed within a casing. Radially outward source flow of brine goes into a shrouding tank and concentrates while a radially inward sink flow of fresh water flows back over the pump to axial extraction. An axial pump drives sink flow and axial extraction. Convergent sink flow passes under an inductor to an axial exhaust port. Induced viscosity and inductive repulsion hinder the passage of brine in sink flow, so only fresh water can reach the axial exhaust port. Crystallization of scale-forming salts is aided by Joule heating from the inductor. Solvent and gases are continuously axially extracted in sink flow, favoring crystallization. Sodium chloride is cooled and crystallized in the shrouding tank. Brine comprising other salts flows out of the tank to treatment by suitable means. Thus brine is separated into fresh water, crystallized salt, and concentrated brine.

Abstract: The invention relates to a method for obtaining viruses from a liquid viral suspension, according to which: the viral suspension is subjected to density gradient ultracentrifugation, the ultracentrifugation is carried out continuously, and the density gradient is a discontinuous gradient comprising at least 2 steps.

Abstract: A concentrator is used for concentrating a fluid, particularly a plasma component out of blood, for treatment of a patient. The concentrator apparatus includes a main housing defining a centrifuge chamber, that also holds the filter. The concentrator allows viewing of the fluid after centrifuging, with an outlet port positionable at a height corresponding to the level of the fraction of the fluid to be further concentrated. Once the fluid is centrifuged, a portion of the fluid is drawn through the outlet, and then pressured past the filter to further concentrate the fluid using the same vessel as used for centrifuging. The same plunger is preferably used to draw centrifuged fluid from the centrifuge chamber as to pressure the centrifuged fluid past the filter.

Abstract: The PRP separator-concentrator of this invention is suitable for office use or emergency use for trauma victims. The PRP separator comprises a motorized centrifugal separation assembly, and a concentrator assembly. The centrifugal separator assembly comprises a centrifugal drum separator that includes an erythrocyte capture module and a motor having a drive axis connected to the centrifugal drum separator. The concentrator assembly comprises a water-removal module for preparing PRP concentrate. The centrifugal drum separator has an erythrocyte trap. The water removal module can be a syringe device with water absorbing beads or it can be a pump-hollow fiber cartridge assembly. The hollow fibers are membranes with pores that allow the flow of water through the fiber membrane while excluding flow of clotting factors useful for sealing and adhering tissue and growth factors helpful for healing while avoiding activation of platelets and disruption of any trace erythrocytes present in the PRP.