Abstract: During a dialysis treatment carried out by a dialysis apparatus, in which a dialysis liquid is circulated to a clean dialysate filter (43) arranged before a dialyser (3), the conductivity of the dialysis liquid is altered according to an altering function that is a function of a mathematical model of the filter (43), in a way that will make the conductivity after the filter change more quickly. A conductivity cell (47), which is arranged after the dialyser, measures the conductivity of the spent dialysis liquid changed in response to said alteration. A control and computer system (52) evaluates the dialysance from said measured response. The conductivity can be changed for a comparatively short time period that is sufficient to allow reliable results.

Abstract: A disposable cartridge for use in a hemodialysis machine has a blood flowpath for carrying a volume of blood to be treated in a dialyseer and a dialysate flowpath, isolated from the blood flowpath, for delivering a flow of dislysate solution through the dialyser. The cartridge is received in an engine section of the machine. The engine section has first and second platens which close when the cartridge is inserted to retain the cartridge. Actuators and sensors arranged on the second platen control operation of the cartridge.

Abstract: A dehydrating apparatus, a dehydration system, and a dehydration method have improved membrane performance. The dehydrating apparatus 1 includes, in a dehydrating apparatus body, a water separation membrane module 10 in which a water separation membrane having at least one flow path extending in the up and down direction to cause a liquid to pass through is provided with a liquid inlet at the bottom thereof and a liquid outlet at the top thereof; and a shell 11 defined by the outer surface of the water separation membrane module and the inner wall of the dehydrating apparatus body. A heater 12 is provided in the shell near the liquid outlet, and a connection port 14 for connection with a pressure reducing device 13 is provided in the shell near the liquid inlet. As the liquid rises in the water separation membrane, water in the liquid permeates the water separation membrane and moves into the shell, by which the liquid is dehydrated.

Abstract: A system for monitoring water quality for dialysis, dialysis fluids, and body fluids treated by dialysis fluids, is disclosed. The system uses microelectromechanical systems (MEMS) sensors for detecting impurities in input water or dialysis fluid, and in the prepared dialysate. These sensors may also be used to monitor and check the blood of the patient being treated. These sensors include ion-selective sensors, for ions such as ammonium or calcium, and also include amperometric array sensors, suitable for ions from chlorine or chloramines, e.g., chloride. These sensors assist in the monitoring of water supplies from a city water main or well. The sensors may be used in conjunction with systems for preparing dialysate solutions from water for use at home or elsewhere.

Abstract: Methods and apparatus for desolvating flowing liquid streams while retaining temporal resolution of dissolved substrates are disclosed. A novel small-scale self-regulating spray dryer preserves temporal resolution while desolvating a liquid chromatography eluent stream and depositing the solute onto an optical surface for infrared spectrographic analysis. The liquid eluent is pumped through a heated nebulizer to create a high-speed jet of solute containing liquid and solvent vapor. This jet is directed circumferentially inside a hot cylindrical cavity. Centrifugal force causes the larger liquid droplets to travel along the outer diameter of the cavity. The cavity surface is heated to cause the droplets to film boil. Film boiling reduces droplet contact with the cavity surface thereby retaining the solute in the droplets. The solute temperature is limited by controlling the pressure into which the solvent evaporates from the droplets.

Abstract: The invention relates to a fluid filter (1) comprising a collecting chamber (10) for a liquid which is separated from the fluid, in addition to a filter insert (4) which comprises a filter medium which is permeable to the fluid. The collecting chamber is arranged below the filter medium (5), and a liquid sensor (19) is arranged above the deepest point of the collecting chamber (10) and the liquid sensor (19) is protected from the liquid, at least sectionally, by means of a protective wall (18, 20). Said protective wall (18, 20) extends laterally and/or below the liquid sensor (19) and a liquid permeable connection is provided from the collecting chamber (10) to the fluid sensor (19).

Abstract: A method of producing safe drinking water from virtually any water source utilizing a water purification system is disclosed. The method includes a combination of water purification methods with a control system that evaluates water quality and functional processing parameters, such as pressure and flow. The control system determines what water processing methods to utilize and how most efficiently to operate them. The system is capable of treating highly contaminated water to the necessary degree to produce safe drinking water. Furthermore, the system regulates and cleans itself to maintain functionality despite receiving high concentrations of various contaminants from the feed water source.

Abstract: Reverse osmosis filtration systems that are self contained and easily converted from above the counter use to below the counter use. The systems feature a simple construction, including a two piece manifold assembly to which filters, including a reverse osmosis filter, a product water storage tank and a control valve connect, all without separate fasteners. The manifold assembly provides all water connections within the system, and includes connections to connect to a water supply, a drain, two dispensers and to an auxiliary water storage tank. The system pressurizes squeeze water for product water dispensing, providing maximum efficiency, maximum storage capacity for a given tank size and maximum pressure for dispensing product water. Various embodiments are disclosed.

Abstract: A blood purification device confirms whether a specific peak is provided by e.g. an ultrafiltration pump, to concentrate the blood or not and also accurately measures a blood re-circulation with a minimum of parameters providing a ratio of re-circulating blood. The blood purification device composed of arterial blood circuit route 1a and venous blood circuit route 1b, blood pump 3, dialyzer 2, water removal pump 8 providing the specific peak in the variation of blood concentration by removing water rapidly, and a detector detecting the specific peak, can measure the blood re-circulation thereby. The re-circulating blood flowing is the blood which was introduced again to arterial blood circuit route 1a after it had been returned to a patient from venous blood circuit route 1b. A first detector 5a installed in the arterial blood circuit route 1a and a second detector 5b installed in venous blood circuit route detector.

Abstract: This disclosure generally relates to dialysis systems and related methods. In one aspect of the invention, a dialysis system includes a device configured so that a medical fluid can pass therethrough, and the device is adapted to remove one or more substances from the medical fluid as the medical fluid passes through the device. The dialysis system can also include a sodium control system adapted to alter a sodium concentration of the medical fluid.

Abstract: A filtration system is disclosed that uses a combination of dead end filtration across opposing membranes with a sample take-off in the middle and cross-flow to prevent cake formation on these opposing filters. In one embodiment is a system that uses opposing filters with a central collection chamber that flips flow back and forth between the sides at a frequency that minimizes filter cake formation. In another embodiment, a combination flip-flip, cross flow system is disclosed. An additional embodiment discloses an actuator valve driven sampling system, in which valves collect the cross flow/counter flow filter cake samples as they are liberated from a filter surface and a quick through filter fluid pulse loosens the sample cake from the filter material. The invention increases effective operation time, allows for continuous filtration operation without interruption, and provides filtered samples that accurately represent the concentration of macromolecular species in industrial systems.

Abstract: A system and method for treating wastewater by continuously flowing wastewater into a chemostat and continuously discharging clean water out of the chemostat. The system can include sensors and an electronic controller for on-line measuring ambient parameters in the chemostat and adjusting the chemostat's operating conditions accordingly.

Abstract: A condensate filtering device of the present invention comprises a simulation unit which is able to simulate operating conditions being the same as operating conditions of a main body of an actual condensate filtering device and sample a hollow fiber membrane easily. The condensate filtering device comprises a unit evaluating properties of a hollow fiber membrane provided with a main body of the condensate filtering device containing a first hollow fiber membrane module in which filtration of condensate and air scrubbing washing are repeated, and equipped with a column containing a second hollow fiber membrane module having a hollow fiber membrane which is the same kind as the hollow fiber membrane of the first hollow fiber membrane module; and a line introducing the condensate for unit which is a branched line from a line introducing the condensate directing to the main body of the condensate filtering device and introduces the condensate into the unit evaluating the properties of the hollow fiber membrane.

Abstract: A machine (1) for extracorporeal blood treatment comprises a device (2) for ultrafiltration of a liquid through a semi-permeable membrane (3) of a blood treatment device (4), a first sensor (11) for ultrafiltration rate through the membrane, a second group of sensors (13) for measuring a trans-membrane pressure, and a programmed controller (14) for calculating a maximum ultrafiltration rate as a function of the transmembrane pressure. The machine is suitable for kidney failure treatments, such as hemofiltration and hemodiafiltration. In a relatively short time the machine enables a large quantity of corporeal blood to be removed from the patient.

Abstract: Membranes comprising functional polyarylether having structural units of formula I are useful for hemodialysis and hemofiltration: wherein X is selected from Br, NR4R5, OOCR6, OR7, NR4CONR5R6, NR4COOR5R6 and combinations thereof; R1, R2 and R3 are independently at each occurrence CH2X, H, halo, cyano, nitro, a C1-C12aliphatic radical, a C3-C12cycloaliphatic radical, a C3-C12aromatic radical or a combination thereof; R4 and R5 are independently H, a C1-10 aliphatic radical, a C3-C12cycloaliphatic radical, a C3-C12 aromatic radical, or a combination thereof; R6 is H, a C2-10 aliphatic radical, a C3-C12 cycloaliphatic radical, a C3-C12 aromatic radical or a combination thereof; R7 is OCH2CH2(OCH2CH2)nOH or OOCCH2(OCH2CH2)nCH3; Z is a direct bond, O, S, SO, SO2, CO, phenylphospinyl oxide, alkenyl, alkynyl, a C1-C12aliphatic radical, a C3-C12cycloaliphatic radical, a C3-C12 aromatic radical or a combination thereof; a, b, and c are independently 1 or 2; and m, n and p are independently 0 or 1.

Abstract: In accordance with the present invention, there are provided methods for improving performance of hollow fiber filtration membrane modules. Invention methods comprise a unique backwashing technique wherein the hollow fiber membranes within the module are pressurized with a gas on the feed side at specified times during the backwash. Periodic use of invention methods effectively removes fouling components from the hollow-fiber membranes, thereby providing stable permeability and low trans-membrane pressures, which results in an efficient and economic filtration process. In addition, there are provided methods for cleaning hollow fiber membranes and increasing filtrate flow rate through membranes.

Abstract: This invention is directed to an integrated process and system for water treatment, in particular, an integrated process and system for water treatment in the beverage manufacture cycle. The water treatment process is directed to treating an influent water solution, a low sugar concentration solution, and a high sugar concentration solution. The water treatment system is directed to a system for treating an influent water solution, a system for treating a low sugar concentration solution, and system for treating a high sugar concentration solution.

Abstract: A fluid treatment system includes at least one flow-through tank, a treatment device configured for treating at least one of an untreated fluid and a treated fluid and providing the treated fluid to the at least one flow-through tank and at least one sensing device configured for sensing the quality of fluid in the at least one flow-through tank. The sensing device is connected to the treatment device for providing the treated fluid to the at least one flow-through tank upon a determination of a quality of fluids in the at least one flow-through tank being less than or equal to a predetermined fluid quality threshold.

Abstract: A water treatment system and method including a membrane-based boron removal unit includes a boron analyzer for detecting the concentration of boron in a treatment stream. The boron removal unit can be a reverse osmosis (RO) or electrodeionization (EDI) treatment unit. A controller responds to the detected boron concentration to control an operation of the RO or EDI units. In an EDI system, the controller may adjust current or voltage supplied to match current to changes in ionic load and maintain a portion of the dilute cell in a substantially regenerated state. In an RO system, the controller may control the high pressure side flow rate, the brine blowdown rate, the product water permeation rate, pH, or feed rate of chemicals in response to the detected boron concentration value.

Abstract: The device according to the invention serves to set up a dilution measurement site on a hemodialyzer. Using such a measurement site, it is possible to determine the filling status of a dialysis patient during dialysis treatment, by means of dilution measurements. Checking the fluid balance by means of weighing the dialysis patient, which is subject to error, can be eliminated. The arterial connection piece is connected with an arterial fistula needle, and the venous connection piece is connected with a venous fistula needle as the blood vessel access. The venous connection piece has an injection channel through which a bolus required to perform a dilution measurement can be injected into the blood, which flows through the venous connection piece coming from the hemodialyzer, in the direction of the venous blood vessel access.

Abstract: A blood leak detector is disclosed having a light source projecting a beam along an optical path, wherein the beam has a wavelength in a range of about 800 to 930 nm; a light detector receiving the beam through an aperture having a diameter in a range of 30 to 60 thousands of an inch; and a housing to receive a tubular liquid passage between the light source and light detector, the housing having a slot transverse to the optical path to receive the tubular liquid passage and the slot has a width narrower than the tubular liquid passage when uncompressed.

Abstract: A water treatment system for treating coal-bed-methane (CBM) water. The CBM water treatment system includes a pump system for pumping CBM water from one or many CBM wells into a common reservoir and a solid-based sulfurous generator that produces aqueous sulfurous acid to treat the CBM water and an injection system that increases the amount of calcium contained in CBM water. In one embodiment, the injection system is a gypsum injector that injects soluble gypsum into the CBM water. Moreover, in one embodiment, the solid-based sulfurous generator includes a hydraulic air inlet shut off valve safety system for automatically reducing the combustion air to the sulfurous generator when water is not delivered to the solid-based sulfurous generator.

Abstract: An apparatus and method recycles the abrasive fluid or slurry effluent used in the polishing step in the manufacture of semiconductors. Agglomerations of abrasive grains built up in the slurry effluent are crushed using a mill, ultrasonic oscillation, or pressurized circulation. The slurry effluent is then regenerated and reused.

Abstract: A blood leak detector is disclosed having a light source projecting a beam along an optical path, wherein the beam has a wavelength in a range of about 800 nm to 930 nm; a light detector receiving the beam; a housing with a slot to receive a transparent tube between the light source and light detector and aligned with the optical path.

Abstract: This invention provides a method and apparatus for a hemodiafiltration delivery module that is used in conjunction with a UF controlled dialysis machine to enable hemodiafiltration therapy to be performed. The advantage is that one can fully utilize a current functioning dialysis machine to perform a hemodiafiltration therapy as opposed to purchasing a completely new machine that offers this capability.

Abstract: A process is provided to produce water that will meet the specifications of the United States Pharmacopeia Inc. for Purified Water and Water for Injection, and water for dialysis as circumscribed by the American Association for Advancement of Medical Instrumentation (AAMI). The system has no storage tanks where stagnant water will be fouled by biofilm colonizing the tank surface. Water is circulated throughout the purification system and drawn as required, on demand. The water is purified and used immediately or recycled and repurified to ensure quality. Sanitation of the purification system, maintaining microbiological purity and cleaning is done by controlling the pH so that it is normally acidic by maintaining a high carbon dioxide concentration in solution, the carbon dioxide being allowed to pass into the permeate from a reverse osmosis membrane assembly used to purify the water.

Abstract: A method of setting up a dialysis treatment in a dialysis machine (1) provided with a device (6) for setting up the dialysis treatment, possessing a microprocessor (11), a data input (12, 13) and a screen (13), comprises the steps of: supplying a group of functions (U(t, P); C(t, P)) of a quantity (U; C) that is characteristic of the dialysis treatment as a function of time (t) and of a parameter (P) correlated with intermediate values (U1, C1) of each function (U(t; P); C(t; P)) of the group; selecting a subset of the group of functions (U(t, P); C(t; P)) imposing boundary conditions (U0, TWL, DT; C0, Cf, DT; C0, CS, DT) that are characteristic of a particular therapy; assigning values to the parameter (P) and displaying the curves corresponding to the functions (U(t, P); C(t, P)) of the subset and to the respective values assigned to parameter (P); and selecting one of the functions ((U(t, P); C(t, P)) of the subset on the basis of the images of the curves.

Abstract: A method of setting up a dialysis treatment in a dialysis machine may include the steps of determining conditions of a dialysis treatment adapted to a specific patient, determining a first function (U(t)) of a first quantity (U) characterizing the dialysis treatment as a function of time (t), and determining a second function (C(t)) of a second quantity (C) characterizing the dialysis treatment. The first function (U(t)) satisfying the conditions of the dialysis treatment and corresponding to a curve having a defined shape. The second function (C(t)) is correlated with the first function (U(t)) by constants (M, N) determined experimentally and the second function (U(t)) corresponding to a curve having a shape of the same kind as the shape as the first curve.

Abstract: A water treatment system and method including a membrane-based boron removal unit includes a boron analyzer for detecting the concentration of boron in a treatment stream. The boron removal unit can be a reverse osmosis (RO) or electrodeionization (EDI) treatment unit. A controller responds to the detected boron concentration to control an operation of the RO or EDI units. In an EDI system, the controller may adjust current or voltage supplied to match current to changes in ionic load and maintain a portion of the dilute cell in a substantially regenerated state. In an RO system, the controller may control the high pressure side flow rate, the brine blowdown rate, the product water permeation rate, pH, or feed rate of chemicals in response to the detected boron concentration value.

Abstract: A first flow path is defined within a first panel that forms a part of an extracorporeal fluid circuit. A second flow path is defined within a second panel that also forms a part of the extracorporeal fluid circuit. The first and second panels are oriented in a fluid processing cartridge for mounting as an integrated unit on a fluid processing machine and for removal as an integrated unit from the fluid processing machine.

Abstract: A measuring apparatus for the determination of parameters of medical fluids with a measured region which including a measuring chamber device for receiving a disposable cassette with at least one measuring chamber through which the fluid to be measured is guided, and at least one measuring element for measuring a measured value whose value depends on the extent of the measuring chamber in a measuring direction and allows the determination of the parameter, or of a value being in a fixed relationship thereto, with a known extent of the measuring chamber. A distance sensor unit is provided which is arranged relative to the measuring chamber such that the measured distance changes relative to the extent of the measuring chamber. A method is also provided for the determination of parameters of medical fluids which can be carried out with the measuring apparatus, and for the calibration of the measuring apparatus.

Abstract: A disposable, integrated extracorporeal blood circuit employed during cardiopulmonary bypass surgery performs gas exchange, heat transfer, and microemboli filtering functions in a way as to conserve volume, to reduce setup and change out times, to eliminate a blood reservoir, and to substantially reduce blood-air interface. Blood from the patient or prime solution is routed through an air removal device that is equipped with air sensors for detection of air. An active air removal controller removes detected air from blood in the air removal device. A disposable circuit support module is used to mount the components of the disposable, integrated extracorporeal blood circuit in close proximity and in a desirable spatial relationship to optimize priming and use of the disposable, integrated extracorporeal blood circuit. A reusable circuit holder supports the disposable circuit support module in relation to a prime solution source, the active air removal controller and other components.

Abstract: A dialysis machine may include a main control unit provided with a memory that stores the parameters of a dialysis treatment carried out on a patient and a plurality of slave control units interacting with the main control unit. The slave control unit may provide the control of the dialysis treatment carried out on the patient. A functionality checking unit may include a memory that stores dialysis treatment parameters and interacts with the main control unit to carry out checking of the functionality of the dialysis machine. At predetermined intervals of time, the functionality checking unit may send the dialysis treatment parameters stored in its memory to the main control unit, and the main control unit may compare the dialysis treatment parameters stored in its memory with those sent from the functionality checking unit, and generate an alarm signal if the dialysis treatment parameters do not coincide with each other.

Abstract: The invention relates to a method for the extra-corporeal qualitative and/or quantitative recording of neuro-toxic substances in the blood plasma of an individual. According to said method, a system containing neurones or neuronal networks, which have been cultivated on or applied to a micro-electrode array or a neuro-chip, in addition to a device for measuring the electrical activity of at least one or several of said neurones are provided, the neurones are brought into contact with a prepared sample of plasma and the electrical activity of the neurones is measured. The aim of the invention is to develop and improve said method in such a way that it supplies reliable, reproducible results for the recording of neuro-toxic substances in the blood plasma of an individual, in particular in the case of encephalopathic conditions, such as for example hepatic failure, or of coma conditions of various origins.

Abstract: A method of separating a mixture into a plurality of more concentrated products utilizing recirculation and concentration of one product so as to extract a substantially large fraction of another product from the mixture; and the apparatus utilizing the present method in a system, such as a reverse osmosis system, capable of very high recovery rates, efficient power usage, and long component life. Substantially 100% of the concentrate product exiting a tangential separation device, such as a reverse osmosis filtering device, recirculates until the concentration of the concentrate reaches a predetermined level, at which time the concentrate is purged from the system and a new cycle begins. This achieves recovery rates in RO-based water purification systems from around 70% for feed water with 1,000 ppm of total dissolved solids to around 97% for feed water with 100 ppm of total dissolved solids.

Abstract: A multipurpose hemofiltration system (10) and method are disclosed for the removal of fluid and/or soluble waste from the blood of a patient. The system (10) continuously monitors the flow rates of drained fluid, blood, and infusate. When necessary, the pumping rates of the infusate, drained fluid and blood are adjusted to remove a preselected amount of fluid from the blood in a preselected time period. A supervisory controller (160) can monitor patient parameters, such as heart rate (120) and blood pressure (130), and adjust the pumping rates accordingly. The supervisory controller (160) uses fuzzy logic to make expert decisions, based upon a set of supervisory rules, to control each pumping rate to achieve a desired flow rate and to respond to fault conditions. An adaptive controller (162) corrects temporal variations in the flow rate based upon an adaptive law and a control law.

Abstract: A blood purification device that does not require measurement of a patient's blood concentration performed ahead of time and that allows treatment time to be reduced, thus reducing the burden on the patient, and allows monitoring of problems in the internal elements. The present invention includes: blood purification device main units including a blood pump disposed in an arterial blood circuit, a blood purification device purifying blood, and an ultrafiltration pump for draining water from blood; first measuring means and second measuring means measuring hematocrit values and disposed at the arterial blood circuit and the venous blood circuit respectively; calculating means calculating a ratio for measured hematocrit values and a ratio for a theoretical hematocrit values determined from a predetermined equation and evaluating means evaluating whether the values determined by calculating means are roughly similar.

Abstract: The present invention is a water processing method comprising the steps of separating boron-containing water in a reverse osmosis membrane module to provide a permeated water and subjecting a part of the obtained permeated water to boron removal using an adsorbent, wherein the water subjected to the boron removal is mixed with the water not subjected to the boron removal of the permeated water to provide a mixed water. The present invention provides economic water processing method and apparatus that remove the boron from boron-containing water.

Abstract: It is an object of the present invention to provide an ultrapure water producing apparatus with reduced problems resulting from impurities generated after replacement of unit apparatuses. A TOC-UV (1), a CP (2) and a UF film (3) are provided in this order from the upstream side of a pure water supply route. Ultrapure water flowing through the UF film (3) is supplied to a use point. A branch route branched from the pure water supply route is provided downstream of the UF film (3). A dissolved oxygen concentration meter (M1) is interposed in the branch route for measuring dissolved oxygen concentration in ultrapure water passed through the UF film (3). The branch route is connected to an oxidant decomposition unit (11). Oxidants included in ultrapure water flowing through the branch route are all converted into DO at the oxidant decomposition unit (11).

Abstract: This invention relates to a method and a device for purifying water by means of inverted osmosis, ultra or nanofiltration or the like. The device comprises a raw water inlet (10) which via a pressurizing pump (15) is connected to a filter housing (24) in order to achieve an increased pressure of the water in the filter housing. The filter housing comprises a filter inlet (23), an outlet conduit (27) for purified water and a reject outlet (29) which is connected to a first branched off conduit (20) connected to the filter inlet (23) in order to form a circulation circuit (19) for concentrated unpurified water. The circulation circuit comprises a circulation pump (21) and a second branched off conduit (31) connected to a sewage drain (32) or the like for tapping off unpurified water.

Abstract: A number of improvements relating to methods and apparatuses for kidney dialysis are disclosed.

Abstract: A dialysis apparatus includes a dialysis liquid circuit for circulating sodium chloride and sodium bicarbonate through a haemodialyzer and a circuit for infusing a patient with at least one solution containing at least one ionic substance “A” absent from the dialysis liquid. The substance “A” has a determined concentration (A)sol in the infusion solution.

Abstract: Processes and apparatus are disclosed for producing clear reverse osmosis retentates having silica concentrations which are substantially supersaturated in silica from feedwaters having silica concentrations, without substantial formation of alkali-soluble scale having substantial silica content in the associated reverse osmosis apparatus, by adjusting the pH of such feedwaters to an acidic pH range prior to reverse osmosis in accordance with this invention. Also disclosed are related processes and apparatus for periodically removing minor amounts of alkali-soluble scale having substantial silica content from the apparatus.

Abstract: A method for testing the integrity of a membrane includes steps of placing a magnetically susceptible material in a fluid upstream of the membrane, collecting the material downstream of the membrane using a magnetic field, and detecting the material using a sensor.

Abstract: A single tank submerged membrane bioreactor for treating feed water having unacceptable levels of ammonia or total nitrogen has both a membrane scouring bubble supply and an oxygenating bubble supply. The membrane scouring bubble supply continuously provides large scouring bubbles to clean the membranes. Permeate is continuously withdrawn from the membranes at a high rate but the large scouring bubbles do not transfer sufficient oxygen to the mixed liquor to create aerobic conditions in the reactor. The oxygenating bubble supply is operated to provide small bubbles of air or oxygen that intermittently produce aerobic conditions in a significant part of the mixed liquor. Alternating aerobic and anoxic conditions occur in a significant portion of the tank suitable for nitrification and denitrification.

Abstract: A method of supplying ready-to-use dialysis fluid in a machine for extracorporeal blood treatment, is described, said machine having, in addition to a dialyzer, at least one sterile filter divided by a microbe-retaining membrane into a first and second chamber. The temperature and/or conductivity of the dialysis fluid flowing through the sterile filter is monitored. To prevent dialysis fluid whose temperature and/or conductivity does not correspond to a preset temperature and/or conductivity value from flowing out of the second chamber of the sterile filter into the dialyzer after rinsing off the membrane of the sterile filter, the dialysis fluid flowing out of the sterile filter is first removed into the drain through a bypass line until the proper values are established. Only then is the dialyzer connected to the dialysis fluid path. In addition, the invention relates to a machine for extracorporeal blood treatment with a device for supplying ready-to-use dialysis fluid.

Abstract: The resist stripping waste liquid regenerating apparatus of the invention regenerates a resist stripping waste liquid to obtain a resist stripping regenerated liquid. The apparatus is provided with a membrane separating apparatus which employs a membrane with a molecular weight cutoff of 100-1500 to separate a resist stripping waste liquid into a concentrated liquid and a permeating liquid, an adjusting tank which stores the permeating liquid and adjusts the concentration of an alkanolamine and organic solvent, means for supplying the alkanolamine to the adjusting tank, and means for supplying the organic solvent to the adjusting tank. This construction adequately reduces the resist concentration of the permeating liquid since the resist in the resist stripping waste liquid cannot permeate the membrane. It is thereby possible to lessen the need for dilution of the resist concentration and thus satisfactorily reduce the amount of alkanolamine and organic solvent supplied to the adjusting tank.

Abstract: A process is provided to produce water that will meet the specifications of the United States Pharmacopeia Inc. for Purified Water and Water for Injection, and water for dialysis as circumscribed by the American Association for Advancement of Medical Instrumentation (AAMI). The system has no storage tanks where stagnant water will be fouled by biofilm colonizing the tank surface. Water is circulated throughout the purification system and drawn as required, on demand. The water is purified and used immediately or recycled and repurified to ensure quality. Sanitation of the purification system, maintaining microbiological purity and cleaning is done by controlling the pH so that it is normally acidic by maintaining a high carbon dioxide concentration in solution, the carbon dioxide being allowed to pass into the permeate from a reverse osmosis membrane assembly used to purify the water.

Abstract: An apparatus and method for separating and analyzing a component of a fluid sample that is considered to be a contaminant, and particularly, that is or may be an organic material. The invention is predicated on the introduction of the sample fluid in a pulsed manner via a first carrier fluid into a feed chamber. A membrane is located between the feed chamber and an exit chamber, and in fluid registry therewith. When the sample enters the feed chamber, the component to be separated and analyzed can permeate the membrane, and thus passes through the membrane to the exit chamber, and then enters a second carrier fluid which carries it to a detector for analysis. The detector may be a gas chromatograph (GC), mass spectrometer (MS) or the like.

Abstract: The invention relates to a measuring apparatus for the determination of parameters of medical fluids with a measured region which comprises a measuring chamber device for receiving a disposable cassette with at least one measuring chamber through which the fluid to be measured is guided and at least one measuring element for measuring a measured value whose value depends on the extent of the measuring chamber in a measuring direction and allows the determination of the parameter to be determined, or of a value being in a fixed relationship thereto, with a known extent of the measuring chamber. In accordance with the invention, a distance sensor unit is provided which is arranged relative to the to the measuring chamber such that the measured distance changes relative to the extent of the measuring chamber.