Using A Nuclear Resonance Spectrometer System Patents (Class 324/307)
  • Patent number: 10962619
    Abstract: A method of performing diffusion basis spectrum imaging (DBSI) within a tissue of a patient using diffusion magnetic resonance data acquired from a portion of the tissue is disclosed. The diffusion magnetic resonance data includes a plurality of diffusion MR signals associated with one voxel and the one voxel represents an image of the portion of the tissue. The method includes computing an isotropic diffusion portion of the diffusion magnetic resonance data representing isotropic diffusion within the one voxel and dividing the isotropic diffusion portion, which includes a fraction of the diffusion magnetic resonance data representing isotropic diffusion, into a restricted isotropic diffusion portion and a non-restricted isotopic diffusion portion. The restricted isotropic diffusion portion includes a fraction of the isotropic diffusion portion with an apparent diffusion coefficient of less than 0.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: March 30, 2021
    Assignee: Washington University
    Inventors: Sheng-Kwei Song, Qing Wang, Yong Wang
  • Patent number: 10962611
    Abstract: Microwave resonator readout of the cavity-spin interaction between a spin defect center ensemble and a microwave resonator yields fidelities that are orders of magnitude higher than is possible with optical readouts. In microwave resonator readout, microwave photons probe a microwave resonator coupled to a spin defect center ensemble subjected to a physical parameter to be measured. The physical parameter shifts the spin defect centers' resonances, which in turn change the dispersion and/or absorption of the microwave resonator. The microwave photons probe these dispersion and/or absorption changes, yielding a measurement with higher visibility, lower shot noise, better sensitivity, and higher signal-to-noise ratio than a comparable fluorescence measurement. In addition, microwave resonator readout enables coherent averaging of spin defect center ensembles and is compatible with spin systems other than nitrogen vacancies in diamond.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: March 30, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: John F. Barry, Erik R. Eisenach, Michael F. O'Keeffe, Jonah A. Majumder, Linh M. Pham, Isaac Chuang, Erik M. Thompson, Christopher Louis Panuski, Xingyu Zhang, Danielle A. Braje
  • Patent number: 10955507
    Abstract: Methods, devices, systems and apparatus for magnetic resonance imaging are provided. In an example, a method includes: obtaining M imaging data sets collected by a receiving coil array including N coil channels under M radio-frequency excitations, determining odd echo phase information and even echo phase information for each of the imaging data sets, mapping M odd echo data sets and M even echo data sets of the imaging data sets as a virtual imaging data set for a virtual coil array that includes N×M×2 virtual coil channels, and performing parallel magnetic resonance imaging based on the odd echo phase information and the even echo phase information of each of the imaging data sets, the virtual imaging data set and parallel reconstruction reference data.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: March 23, 2021
    Assignee: Shanghai Neusoft Medical Technology Co., Ltd.
    Inventors: Zhigang Wu, Ruibo Song, Feng Huang
  • Patent number: 10957038
    Abstract: Methods, systems, and computer readable media are provided for processing medical images. One or more prior medical images are aligned with a current medical image. Image subtraction between the current medical image and the one or more prior medical images is performed to produce one or more difference images. The one or more difference images are applied to a machine learning model to determine a presence or an absence of a medical condition.
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: March 23, 2021
    Assignee: International Business Machines Corporation
    Inventor: William M. Stoval, III
  • Patent number: 10955497
    Abstract: A phase compensation circuit includes a phase difference voltage detection module configured to process an inputted detection signal and an inputted reference signal, calculate a magnitude ratio or a phase difference of the processed detection signal and reference signal, and then output a first phase difference voltage signal according to the amplitude ratio or the phase difference.
    Type: Grant
    Filed: May 9, 2019
    Date of Patent: March 23, 2021
    Assignees: Beijing BOE Optoelectronics Technology Co., Ltd., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Wei Li, Lei Xu, Meng Shi
  • Patent number: 10955506
    Abstract: A magnetic resonance (MR) imaging technique enables parallel imaging in combination with fat suppression at an increased image quality, notably in combination with EPI. The method includes acquiring reference MR signal data from the object in a pre-scan and acquiring imaging MR signal data from the object in parallel via one or more receiving coils having different spatial sensitivity profiles. The MR signal data are acquired with sub-sampling of k-space and with spectral fat suppression and an MR image is reconstructed from the imaging MR signal data. Sub-sampling artefacts are eliminated using sensitivity maps indicating the spatial sensitivity profiles of the two or more RF receiving coils. A B0 map is derived from the reference MR signal data and the spatial dependence of the effectivity of the spectral fat suppression is determined using the Bo map.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: March 23, 2021
    Assignee: Koninklijke Philips N.V.
    Inventors: Johannes Martinus Peeters, Elwin De Weerdt
  • Patent number: 10955508
    Abstract: A magnetic resonance imaging system (200, 300, 400) includes a radio-frequency system (216, 214) with multiple coil elements (214) for acquiring magnetic resonance data (264) and a memory (250) for storing machine executable instructions (260) and pulse sequence commands (262). The pulse sequence commands are configured for controlling the magnetic resonance imaging system to acquire the magnetic resonance data according to a SENSE imaging protocol.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: March 23, 2021
    Assignee: Koninklijke Philips N.V.
    Inventors: Miha Fuderer, Elwin De Weerdt, Jean-Pierre Franciscus Alexander Maria Ermes
  • Patent number: 10945605
    Abstract: The present invention provides a combined radiotherapy and MRI system in which an imaging coil is mounted on a mechanical arm. The position of the imaging coil is thus known and in embodiments can be controlled to prevent collisions with the patient and unfavourable interactions between the imaging coil and the radiation beam.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: March 16, 2021
    Assignee: ELEKTA LIMITED
    Inventors: Gregory Trausch, Kevin Brown, Dan Thompson
  • Patent number: 10935613
    Abstract: A device for receiving RF signal is provided. The device includes a receiving component configured to receive a radio frequency (RF) signal and a sampling component configured to sample the RF signal. The sampling component may include a plurality of filters, a demultiplexer, a clock synthesizer, an analog-to-digital converter (ADC), and a digital signal processing device. The sampling component may obtain an intermediate frequency (IF) signal based on the plurality of filters, the demultiplexer, the clock synthesizer, the ADC, and the digital signal processing device.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: March 2, 2021
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD
    Inventors: Xiaolei Guan, Jianfan Zhou, Fangyan Hou, Qiang Xie
  • Patent number: 10935619
    Abstract: A system and method for correcting phase shift in echo images are provided. The method may include one or more of the following operations. A plurality of echo images may be obtained. Homogeneous pixels in the plurality of echo images may be identified. A vector corresponding to each of at least some of the identified homogeneous pixels may be determined. A vector of a homogenous pixel includes a phase element and an amplitude element. A first complex linear model of phase shift may be determined based at least in part on the determined vectors. Phase shift of at least one of the plurality of echo images may be corrected based on the first complex linear model.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: March 2, 2021
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Yanen Guo, Zhongqi Zhang
  • Patent number: 10935618
    Abstract: Method for MR imaging of an acquisition region during a patient examination. In order to determine a point spread function, in a prior measurement for each of additional gradient output directions, the method includes choosing, in the acquisition region, a slice lying outside of an isocenter of the MR device, which slice extends in a plane perpendicular to the additional gradient output direction under consideration; following a respective slice-selective excitation of the selected slice, acquiring first calibration data using the additional gradient pulse of the additional gradient output direction under consideration, and acquiring second calibration data omitting the additional gradient pulse in each case along a k-space line, wherein a same timing sequence of additional gradient pulse and readout time window is used as in the MR sequence; and calculating, from the first and second calibration data, the point spread function for the additional gradient output direction under consideration.
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: March 2, 2021
    Assignee: Siemens Healthcare GmbH
    Inventors: Thomas Beck, Daniel Polak
  • Patent number: 10928468
    Abstract: At least one adjustable stiffening device is integrated into a mechanically flexible MR surface coil. The stiffening device can have, in particular, at least one stiffening volume including magnetorheological, electrorheological or thermorheological material. The stiffening device extends at least in one surface direction of the MR surface coil. The MR surface coils positioned on limbs, such as wrapping around, and are stiffened.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: February 23, 2021
    Assignee: Siemens Healthcare GmbH
    Inventor: Andreas Greiser
  • Patent number: 10918344
    Abstract: Systems and methods for estimating arterial flow information can include a processor generating a time attenuation sequence for each point of a pair of points along a segment of a coronary artery structure. The processor can determine the arterial flow velocity between the pair of points using the distance between the pair of points and the difference between average transit times associated with the pair of points. The one or more processors can determine the average transit times across the same time window. The processor can determine the arterial flow velocity between the pair of points using the distance between the pair of points and the difference between a first time duration that a number of particles take to pass by a first point of the pair of points and a second time duration that the number of particles take to pass by the other point.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: February 16, 2021
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Martin G. Wagner, Charles A. Mistretta
  • Patent number: 10921399
    Abstract: Various methods and systems are provided for a flexible, lightweight, low-cost radio frequency (RF) coil array of a magnetic resonance imaging (MRI) system. In one example, a RF coil assembly for a MRI system includes a loop portion comprising distributed capacitance wire conductors, a coupling electronics portion including a pre-amplifier. A coupler slidably connects two adjacent coil loops together. An open area is formed inside the loops enabling tissue manipulation or biopsies from interventional or surgical procedures.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: February 16, 2021
    Assignee: GE PRECISION HEALTHCARE LLC
    Inventors: Stephen Gerard Hushek, Scott Allen Lindsay, Robert Steven Stormont
  • Patent number: 10921410
    Abstract: Method for susceptibility weighted magnetic resonance imaging of vasculature, the method comprising the following steps: —acquiring multi-echo data containing a time-of-flight signal in at least the first echo (S1); —identifying voxels belonging to arteries from the data (S2); and—generating corresponding information on artery presence (S3); The invention further relates to a corresponding system (10) for susceptibility weighted magnetic resonance imaging of vasculature.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: February 16, 2021
    Assignee: Koninklijke Philips N.V.
    Inventors: Guillaume Gilbert, Zhaolin Chen
  • Patent number: 10912952
    Abstract: A high-energy radiation treatment system can comprise a laser-driven accelerator system, a patient monitoring system, and a control system. The laser-driven accelerator system, such as a laser-driven plasma accelerator or a laser-driven dielectric microstructure accelerator, can be constructed to irradiate a patient disposed on a patient support. The patient monitoring system can be configured to detect and track a location or movement of a treatment volume within the patient. The control system can be configured to control the laser-driven accelerator system responsively to the location or movement of the treatment volume. The system can also include a beam control system, which generates a magnetic field that can affect the radiation beam and/or secondary electrons produced by the irradiation beam. In some embodiments, the beam control system and the patient monitoring system can comprise a magnetic resonance imaging system.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: February 9, 2021
    Assignee: VARIAN MEDICAL SYSTEMS, INC.
    Inventor: James E. Clayton
  • Patent number: 10912571
    Abstract: A smooth mating surface model defining a mating surface of a customized arthroplasty jig is generated. For example, sagittal slices of a volumetric image of a patient bone are segmented with segmentation splines. An anatomically accurate model of the patient bone is generated from the segmentation splines. The anatomically accurate model includes anatomically accurate segmentation splines. The anatomically accurate segmentation splines are transformed into mating surface contours. Any inadequate segments of the mating surface contours are modified to obtain modified mating surface contours. A mating surface model of the patient bone is generated based on the mating surface contours and the modified mating surface contours. Three-dimensional cross-sections of the mating surface model are smoothed to generate the smooth mating surface model.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: February 9, 2021
    Assignee: Howmedica Osteonics Corporation
    Inventors: Elena I. Pavlovskaia, Boris E. Shpungin, Oleg Mishin, Olga Sominskaya
  • Patent number: 10916007
    Abstract: According to one embodiment, an MRI apparatus includes a data acquisition unit and an image generation unit. The data acquisition unit acquires MR data from an object. The MR data correspond to a sampling region asymmetric in a wave number direction in a k-space. The image generation unit generates amplitude image data, in a real space, based on first k-space data after zero padding to a non-sampling region of the MR data and generates MR image data by data processing of the amplitude image data or convolution processing of the amplitude image data. The data processing converts the amplitude image data into second k-space data, performs filtering of the second k-space data and converts the second k-space data after the filtering into real space data. The convolution processing uses a function in the real space. The function is derived by converting a window function for the filtering.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: February 9, 2021
    Assignee: TOSHIBA MEDICAL SYSTEMS CORPORATION
    Inventor: Tokunori Kimura
  • Patent number: 10912485
    Abstract: A method of identifying brain structures is disclosed. The method comprises imaging the cortex of the brain via inversion recovery magnetic resonance imaging, such that at least two areas are zeroed in terms of their longitudinal relaxation times, and associating the two areas with different brain structures, thereby identifying brain structures.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: February 9, 2021
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Yaniv Assaf, Daniel Barazany
  • Patent number: 10914798
    Abstract: A method for estimating a coil sensitivity map for a magnetic resonance (MR) image includes providing a matrix A of sliding blocks of a 3D image of coil calibration data, calculating a left singular matrix V? from a singular value decomposition of A corresponding to ? leading singular values, calculating P=V?V?H, calculating a matrix that is an inverse Fourier transform of a zero-padded matrix P, and solving MHcr=(Sr)Hcr for cr, where cr is a vector of coil sensitivity maps for all coils at spatial location r, and M = ( ( 1 1 … 1 0 0 … 0 … … … 0 0 … 0 ) ? ( 0 0 … 0 1 1 … 1 … … … 0 0 … 0 ) ? ? … ? ? ( 0 0 … 0 0 0 … 0 … … … 1 1 … 1 ) ) .
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: February 9, 2021
    Assignee: Siemens Healthcare GmbH
    Inventors: Jun Liu, Hui Xue, Marcel Dominik Nickel, Ti-chiun Chang, Mariappan S. Nadar, Alban Lefebvre, Edgar Mueller, Qiu Wang, Zhili Yang, Nirmal Janardhanan, Michael Zenge
  • Patent number: 10909431
    Abstract: A method and a system for digital direct imaging, an image generating method and an electronic device are provided. The method for digital direct imaging includes: obtaining a first image of a first format; converting the first image into a second image of a second format, wherein the second image includes a contour description; generating a correction parameter according to at least one mark on a substrate; correcting the second image according to the contour description and the correction parameter; and performing a rasterization operation on the corrected second image and imaging the second image processed by the rasterization operation on the substrate by an exposure device.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: February 2, 2021
    Assignee: Industrial Technology Research Institute
    Inventors: Shau-Yin Tseng, Chien-Hung Lin, Yu-Sheng Lee, Yung-Chao Chen, Chih-Wei Hsu
  • Patent number: 10904509
    Abstract: Video data signals are encoded such that the encoded video data signal comprises at least a primary and at least a secondary video data signal. The primary and secondary video data signal are jointly compressed. The primary video data signal is compressed in a self-contained manner, and the secondary video data signal is compressed using data from the primary video data signal. The jointly compressed video data signal is split into separate bitstreams, at least a primary bitstream comprising data for the primary video data signal and at least a secondary bitstream comprising data for the secondary video data signal, whereafter the primary and secondary bitstreams are multiplexed into a multiplexed signal, and the primary and secondary signals are provided with separate codes.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: January 26, 2021
    Assignee: Koninklijke Philips N.V.
    Inventors: Wilhelmus Hendrikus Alfonsus Bruls, Arnaud Pierre Herve Bourge
  • Patent number: 10898089
    Abstract: Example apparatus and methods improve magnetic resonance fingerprinting (MRF) by performing MRF with optimized spatial encoding, parallel imaging, and utilization of field inhomogeneities. Multi-echo radial trajectories and spiral trajectories may acquire data according to sampling schemes based on models of charge distribution on a sphere. Non-uniform sampling schemes may account for differences in detector coil performance. Field inhomogeneities provide spatial information that enhances the spatial separation of an MRF signal and facilitates unaliasing pixels. The field inhomogeneity may be manipulated. An MRF pulse sequence may include frequency selective RF pulses that are determined by the field inhomogeneities. Inhomogeneities combined with selective RF pulses result in higher acquisition efficiency.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: January 26, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Vikas Gulani, Mark Griswold, Dan Ma, Alice Yang
  • Patent number: 10890685
    Abstract: Nuclear magnetic resonance (NMR) methods and apparatus are provided for investigating a sample utilizing NMR pulse sequences. In various embodiments, the NMR pulse sequences have a solid state portion and a line-narrowing portion. In other embodiments, the NMR pulse sequences have a first line-narrowing portion and a second line-narrowing portion where the sequences of the different portions are different. In yet other embodiments, the NMR pulse sequences have a T1 portion and a line-narrowing portion. Processing of detected signals permits determination of characteristics of the sample including, in some cases, a differentiation of multiple components of the sample.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: January 12, 2021
    Assignee: Schlumberger Technology Corporation
    Inventors: Ravinath Kausik Kadayam Viswanathan, Yiqiao Song
  • Patent number: 10890638
    Abstract: A medical instrument includes a magnetic resonance (MR) imaging system with an imaging zone and a gradient coil system with three orthogonal gradient coils. A processor controls the medical instrument to: repeatedly control the MR imaging system with calibration pulse sequence commands to acquire the MR calibration data for multiples slices using at least one of the three orthogonal gradient coils to generate the slice select gradient magnetic field; compute a Fourier transform of the MR calibration data for each of the voxels of the multiple slices in the phase encoding directions; compute an expansion of the Fourier transformed MR calibration data into spherical harmonics; and calculate a three-dimensional gradient impulse response function for the at least one of the three orthogonal gradient coils using the expansion into spherical harmonics.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: January 12, 2021
    Assignee: Koninklijke Philips N.V.
    Inventors: Juergen Rahmer, Tim Nielsen, Peter Boernert
  • Patent number: 10890632
    Abstract: To avoid the complication of an MRI apparatus and avoid the overestimation of a calculated value of SAR without extending a processing time and to perform accurate SAR management. To this end, the MRI apparatus is equipped with a high frequency antenna which has a plurality of channels and resonates at a predetermined frequency, and a measuring instrument which measures the amplitudes of a forward traveling and reflected waves of each high frequency signal supplied to the high frequency antenna. In the MRI apparatus, a reflection matrix S is determined based on the measured amplitudes. Diagonal terms of the determined reflection matrix S are used to calculate Q values for each of the channels. Each non-diagonal term of the reflection matrix S is used to correct the calculated Q value.
    Type: Grant
    Filed: February 14, 2017
    Date of Patent: January 12, 2021
    Assignee: Hitachi, Ltd.
    Inventors: Hideta Habara, Masaharu Ono, Tetsuhiko Takahashi, Hiroyuki Takeuchi
  • Patent number: 10890631
    Abstract: Methods and apparatuses for determining spatial distribution of an absolute phase of RF transmit field B1+ and/or RF receive field B1? in an MRI system are described herein. An example method can include selecting a transmit coil for which to measure the absolute phase of the RF transmit field B1+, exciting nuclear spins in MR nuclei using at least two transmit configurations of the transmit coil, and detecting first and MR signals arising from exciting nuclear spins in MR nuclei using first and second transmit configurations, respectively. The method can also include acquiring first and second sets of complex k-space data from the first and second MR signals, respectively, and estimating an absolute phase B1+ map of the transmit coil using the first set of complex k-space data and the second set of complex k-space data.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: January 12, 2021
    Assignee: Ohio State Innovation Foundation
    Inventors: Jinghua Wang, Yu Ding
  • Patent number: 10888819
    Abstract: A forward or pressure retarded osmosis system using submerged hollow fiber membranes, a draw solution of superparamagnetic nanoparticles (preferably an iron oxide core with a silica shell that is chemically treated with a dispersant stabilizing it in a permanent suspension), that produces an osmotic pressure that drives fluid through the semipermeable membrane and a multiplicity of rigidly connected, permanent ring magnets forming layers, that maintains the locational position of the magnetic nanoparticles inside the hollow fiber membranes, preventing the draw solute particles from leaving membrane surface area. The various magnetic fields produced by the ring magnets attract the magnetic nanoparticles toward the surface area of the membrane preventing dilutive concentration polarization, thereby maximizing permeate flux rate.
    Type: Grant
    Filed: January 25, 2016
    Date of Patent: January 12, 2021
    Inventor: Terrence W. Aylesworth
  • Patent number: 10884091
    Abstract: Described here are systems and methods for using a magnetic resonance imaging (“MRI”) system to estimate parameters of spectral profiles contained in multispectral data acquired using multispectral imaging (“MSI”) techniques, such as MAVRIC. These spectral profile parameters are reliably extracted using an iterative perturbation theory technique and utilized in a number of different applications, including fat suppression, artifact correction, and providing accelerated data acquisitions.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: January 5, 2021
    Assignee: The Medical College of Wisconsin, Inc.
    Inventors: Kevin M. Koch, Suryanarayanan Kaushik
  • Patent number: 10874353
    Abstract: MRI interference with a concurrently operated system may be reduced or corrected by subtracting the MRI interference from signals measured using the concurrently operated system. Various approaches for performing MRI of an anatomic region in conjunction with a radio-frequency-sensitive (RF-sensitive) measurement of the region using a concurrently operated system include the steps of performing an MR scan sequence with the concurrently operated system idle; detecting intervals during the MR scan sequence when an RF level is sufficient to interfere with the RF-sensitive measurement storing data indicative of a temporal extent of the MR scan sequence and the detected intervals; and based at least in part on the stored data, simultaneously performing the scan sequence and operating the concurrently operated system but obtaining the RF-sensitive measurement only during times not corresponding to the recorded intervals.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: December 29, 2020
    Assignee: INSIGHTEC, LTD.
    Inventor: Benny Assif
  • Patent number: 10871534
    Abstract: Systems and methods for accelerated magnetic resonance imaging using a tilted reconstruction kernel to synthesize unsampled k-space data in phase encoded and point spread function (“PSF”) encoded k-space data are provided. Images reconstructed from the data have reduced B0-related distortions and reduced T2* blurring. In general, data are acquired with systematically optimized undersampling of the PSF and phase encoding subspace. Parallel imaging reconstruction is implemented with a B0 inhomogeneity informed approach to achieve greater than twenty-fold acceleration of the PSF encoding dimension. A tilted reconstruction kernel is used to exploit the correlations in the phase encoding-PSF encoding subspace.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: December 22, 2020
    Assignee: The General Hospital Corporation
    Inventors: Kawin Setsompop, Lawrence L. Wald, Zijing Dong, Hua Guo, Fuyixue Wang, Timothy G. Reese
  • Patent number: 10871539
    Abstract: Described herein are exemplary methods for estimating a nonparametric joint radius-length (R-L) distribution of an ensemble of porous elements represented generally by finite cylinders. Some described methods comprise estimating an eccentricity distribution of a group of anisotropic porous elements. For example, disclosed methods can be applied to estimate a nonparametric joint R-L distribution of injured axons in nervous tissue, muscle tissue, plant elements, or other porous materials. Employing a novel three dimensional (3-D) double pulsed-field gradient (d-PFG) magnetic resonance (MR) acquisition scheme, both the marginal radius and length distributions of a population of generally cylindrical porous elements can be obtained. The marginal radius and length distributions can then b e used to constrain and stabilize the estimate of the joint radius-length distribution. Using the marginal distributions as constraints allows the joint R-L distribution to be reconstructed from an underdetermined system (i.e.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: December 22, 2020
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Peter J. Basser, Dan H. Benjamini
  • Patent number: 10866293
    Abstract: Methods and apparatus for operating a low-field magnetic resonance imaging (MRI) system to perform diffusion weighted imaging, the low-field MRI system including a plurality of magnetics components including a B0 magnet configured to produce a low-field main magnetic field B0, at least one gradient coil configured to, when operated, provide spatial encoding of emitted magnetic resonance signals, and at least one radio frequency (RF) component configured to acquire, when operated, the emitted magnetic resonance signals. The method comprises controlling one or more of the plurality of magnetics components in accordance with at least one pulse sequence having a diffusion-weighted gradient encoding period followed by multiple echo periods during which magnetic resonance signals are produced and detected, wherein at least two of the multiple echo periods correspond to respective encoded echoes having an opposite gradient polarity.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: December 15, 2020
    Assignee: Hyperfine Research, Inc.
    Inventors: Rafael O'Halloran, Laura Sacolick
  • Patent number: 10864383
    Abstract: The present disclosure relates to a respiratory gating system for inducing respiration of a patient during radiation therapy. A respiratory gating system according to one embodiment of the present disclosure comprises: an image management unit for acquiring an MRI image of a patient and processing the acquired image; and a projection unit for displaying the MRI image acquired and processed by the image management unit to the patient in real time, wherein the projection unit may be configured to project an image of a treatment area of the patient in real time using, as a screen, a bore of a radiotherapy equipment which is formed to surround the patient in order to acquire the MRI image.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: December 15, 2020
    Assignees: SEOUL NATIONAL UNIVERSITY HOSPITAL, PAPRICA Lab. Co., Ltd.
    Inventors: Hong Gyun Wu, Jong Min Park, Chang Heon Choi, Jung In Kim
  • Patent number: 10859645
    Abstract: Various methods and systems are provided for selecting coil elements of a plurality of coil elements of a radio frequency (RF) coil array for use in a magnetic resonance imaging (MRI) system. In one example, a method includes grouping the plurality of coil elements into receive elements groups (REGs) according to REGs information, generating channel sensitivity maps for the plurality of coil elements, generating REG sensitivity maps based on the REGs information and the channel sensitivity maps, labeling each REG as either selectable or not selectable based on the REG sensitivity maps, selecting one or more REGs from the selectable REGs based on the REG sensitivity maps and a region of interest (ROI), and scanning the ROI with the coil elements in the one or more selected REGs being activated and the coil elements not in any selected the other REGs being deactivated.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: December 8, 2020
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Shaorong Chang, Eric Printz, Ling Sun, Anja Kammeier, Charles Michelich, Zachary Slavens
  • Patent number: 10859621
    Abstract: An electromagnetic interference objective complexity evaluation method based on a fast S-transformation time-frequency space model comprises the following steps: (1) carrying out fast S-transformation on space electromagnetic signals acquired in real time to obtain a fast speed S-transformation two-dimensional time-frequency matrix of the signal; (2) calculating time domain occupancy rate TP, frequency occupancy rate FP, and energy occupancy rate EP of an evaluation object and interference signals in the fast speed S-transformation two-dimensional time-frequency matrix; (3) calculating electromagnetic interference objective complexity C=TP*FP*EP according to the time-frequency space model; and (4) finding a grading standard according to an objective complexity value so as to determine an electromagnetic interference objective complexity type.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: December 8, 2020
    Assignee: WUHAN UNIVERSITY
    Inventors: Baiqiang Yin, Yigang He, Bing Li, Lei Zuo, Hui Zhang, Shudong Wang
  • Patent number: 10859646
    Abstract: Various methods and systems are provided for selecting radio frequency coil array comprising a plurality of coil elements for magnetic resonance imaging. In one embodiment, the method includes grouping the plurality of coil elements into receive elements groups (REGs) according to REGs information; generating REG sensitivity maps; determining, for each REG, signal in a region of interest (ROI) and signal in an annefact source region based on the REG sensitivity maps; selecting one or more REGs based on the signal in the ROI and the signal in the annefact source region; and scanning the ROI with the coil elements in the one or more selected REGs being activated and the coil elements not in any selected REGs being deactivated. In this way, annefact artifacts in the reconstructed image may be reduced.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: December 8, 2020
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Shaorong Chang, Zachary Slavens, Dawei Gui
  • Patent number: 10859655
    Abstract: An imaging system includes determination of a first gradient-modulated offset-independent adiabaticity pulse associated with a first bandwidth and a first gradient strength, determination of a second gradient-modulated offset-independent adiabaticity pulse associated with a second bandwidth less than the first bandwidth and a second gradient strength less than the first gradient strength, determination of a third asymmetric adiabatic pulse based on the first gradient-modulated offset-independent adiabaticity pulse and the second gradient-modulated offset-independent adiabaticity pulse, and control of a radio frequency system and gradient system to apply the third asymmetric adiabatic pulse to patient tissue.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: December 8, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Jin Jin, Xiaoming Bi, Fei Han
  • Patent number: 10849561
    Abstract: In some aspects, the disclosed technology relates to reducing respiratory-induced motion artifacts for accelerated imaging. In one embodiment, magnetic resonance data may be acquired for an area of a subject containing the heart. The acquired data may include motion-corrupted data due to respiration of the subject. From the acquired data, an image may be independently reconstructed for each of a plurality of time frames, with each time frame corresponding to one of a plurality of heartbeats. A region containing the heart of the subject may be automatically detected in the reconstructed images, and rigid motion registration may be performed on the region of the reconstructed images containing the heart. Based on the rigid motion registration, a linear phase shift for motion correction may be determined.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: December 1, 2020
    Assignee: University of Virginia Patent Foundation
    Inventors: Wei Huang, Yang Yang, Xiao Chen, Michael Salerno
  • Patent number: 10852376
    Abstract: Methods and devices for magnetic resonance imaging are provided. In one aspect, a method includes: obtaining undersampled k-space data as first partial k-space data by scanning a subject in an accelerated scanning manner, generating a first image by performing image reconstruction for the first partial k-space data according to a trained deep neural network and an explicit analytic solution imaging algorithm, obtaining mapped data of complete k-space by mapping the first image to k-space, extracting second partial k-space data from the mapped data of complete k-space, the second partial k-space data being distributed in the k-space at a same position as the first partial k-space data in the k-space, obtaining a residual image by performing image reconstruction according to the first partial k-space data and the second partial k-space data, and finally generating a magnetic resonance image of the subject by adding the first image with the residual image.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: December 1, 2020
    Assignee: Neusoft Medical Systems Co., Ltd.
    Inventors: Feng Huang, Mingliang Chen
  • Patent number: 10845445
    Abstract: In general, according to the present embodiment, a magnetic resonance imaging apparatus includes sequence control circuitry and processing circuitry. The sequence control circuitry collects MR data corresponding to each of a plurality of echo times. The processing circuitry generates a plurality of magnitude images corresponding to the plurality of echo times based on the MR data. The processing circuitry generates a relaxation time map of tissue based on the plurality of magnitude images. The processing circuitry generates a susceptibility map quantitatively indicating susceptibility values in a subject based on a magnetic field distribution that is generated based on a plurality of phase images corresponding to the plurality of echo times and the relaxation time map.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: November 24, 2020
    Assignee: Canon Medical Systems Corporation
    Inventor: Taichiro Shiodera
  • Patent number: 10845446
    Abstract: A system and method are provided for controlling a magnetic resonance imaging system to perform a gradient echo pulse sequence that includes varying a phase of an RF pulse of the gradient echo pulse sequence between repetitions and acquire complex MR data. The method includes processing the complex MR data to determine signal contributions from transverse relaxation (T2) in the subject, generating a quantitative T2 map of the subject using the signal contributions from T2 in the subject, and displaying the quantitative T2 map.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: November 24, 2020
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Scott B. Reeder, Xiaoke Wang
  • Patent number: 10838031
    Abstract: In a magnetic resonance (MR) method and apparatus, first and second MR data are acquired from respective echo trains with gradient moments of one echo train being in a sequence that is an inversion of at least a portion of the sequence of gradient moments in the second echo train. The MR signals are acquired from at least two substances in a volume of a subject, so that the relaxation of the respective nuclear spins influences the manner by which the first and second data are entered into k-space, so that when an image is reconstructed, the filter effect induced by such relaxation is compensated for.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: November 17, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Dominik Paul, Mario Zeller
  • Patent number: 10838029
    Abstract: Some implementations provide a system that includes: a main magnet including a bore and configured to generate a substantially uniform magnetic field in the bore; one or more gradient coils configured to perturb the substantially uniform magnetic field in the bore, wherein perturbing the substantially uniform magnetic field results in a first varying magnetic field outside of the bore; and one or more shielding units located outside of the bore and configured to generate a second varying magnetic field configured to attenuate the first varying magnetic field outside of the bore.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: November 17, 2020
    Assignee: Synaptive Medical (Barbados) Inc.
    Inventors: Alexander Gyles Panther, Geron André Bindseil, Chad Tyler Harris, Mark Tullio Morreale
  • Patent number: 10830853
    Abstract: A computer implemented method for measuring T1 in an anatomical region of interest during a dynamic procedure includes acquiring a reference MR image of the anatomical region of interest using a first flip angle. A first set of dynamic MR images of the anatomical region of interest are acquired using a second flip angle. The reference MR image and the first set are used to calculate a reference T1 value for tissue in the anatomical region of interest. During an intervention where the T1 value may change, a second set of dynamic MR images of the anatomical region of interest is acquired using the second flip angle. The reference MR image and the second set are used to calculate an estimated T1 value. The reference T1 value, the estimated T1 value, and the first and second flip angles may then be used to correct the estimated T1 value.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: November 10, 2020
    Assignees: Siemens Healthcare GmbH, University of Utah Research Foundation
    Inventors: Bryant Svedin, Dennis L. Parker, Allison Payne
  • Patent number: 10832421
    Abstract: A method for determining or updating a registration between a 3D image of a region of interest and a set of at least two 2D images of the same region of interest includes selecting at least one respective contour point in the 3D image for each 2D image. A 2D position of a respective depiction of each contour point is determined in the respective 2D image. At least one condition for the registration parameters that needs to be fulfilled is determined, for each contour point, to map the respective contour point to the respective 2D position in the respective 2D image. An updated set of registration parameters is determined by solving a set of equations or an optimization problem that depends on the conditions.
    Type: Grant
    Filed: August 15, 2018
    Date of Patent: November 10, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Anja Borsdorf, Roman Schaffert, Jian Wang
  • Patent number: 10830857
    Abstract: A method and a magnetic resonance tomography (MRT) system are provided. The MRT system includes a controller configured to store a transmit vector that is established on a local-coil-specific basis. The transmit vector, for a specific local coil, indicates with which amplitudes and phases, transmit elements of the local coil may be controlled by a transmit device. The controller is configured to initiate a patient-specific calibration measurement on a patient to generate patient-specific calibration data representing a field distribution. The controller is also configured to determine deviations in the patient-specific calibration data from the stored transmit vector established on a local-coil-specific basis. The patient-specific calibration data is generated in the patient-specific calibration measurement on the patient and represents a field distribution. An imaging MRT measurement is not allowed if deviations exceed a threshold value, but is otherwise performed and is monitored by a monitoring device.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: November 10, 2020
    Assignee: SIEMENS AKTIENGESELLSCHAFT
    Inventors: Ralph Kimmlingen, Norbert Rietsch
  • Patent number: 10830844
    Abstract: The present disclosure discusses systems and methods for imaging tissue. The system can reduce the amount of vibrations that are transmitted from a magnetic resonance imaging device to a tissue sample. The system can include a stabilization platform with at least one vibration dampener coupled towards either end of the stabilization platform. A fluid reservoir is coupled to the stabilization platform and a resonator is coupled to the exterior of the fluid reservoir.
    Type: Grant
    Filed: April 18, 2016
    Date of Patent: November 10, 2020
    Assignee: Cornell University
    Inventors: Douglas J. Ballon, Brittany Dashevsky, Krishna Juluru, Eric Aronowitz, Henning U. Voss
  • Patent number: 10830852
    Abstract: A radio-frequency control system for a magnetic resonance tomography system and a method for the operation thereof are provided. The radio-frequency control system includes a controller and a radio-frequency power amplifier with amplification between a signal input and a signal output of the radio-frequency power amplifier that is dependent on a predetermined frequency response. The controller determines a control pulse for multislice excitation and outputs the pulse to the signal input of the radio-frequency power amplifier. The controller determines a high-frequency power value for the control pulse in dependence on the predetermined frequency response of the radio-frequency power amplifier.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: November 10, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Uvo Hölscher, Stephan Stöcker, Christian Wünsch
  • Patent number: 10823799
    Abstract: In a magnetic resonance imaging method and apparatus for generating a number of image data sets of an image recording region of an examination object, at least one set of reference magnetic resonance raw data is acquired from the image recording region. Furthermore, a number of magnetic resonance raw data sets are acquired temporally sequentially. At least some of the magnetic resonance raw data sets are recorded with an SMS image recording sequence and a number of image data sets are reconstructed on the basis of the acquired magnetic resonance raw data sets. A number of SMS image data sets are each reconstructed on the basis of one of the magnetic resonance raw data sets recorded with an SMS image recording sequence, and each on the basis of one and the same set of reference magnetic resonance raw data.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: November 3, 2020
    Assignee: Siemens Healthcare GmbH
    Inventor: Thomas Beck