Abstract: Disclosed herein is a contact lens comprising a lenticular in a superior portion of the contact lens wherein the contact lens attaches to an upper eyelid of a wearer by the lenticular interacting with an upper tarsal plate of the upper eyelid of a wearer, said interaction allows the contact lens to translate upwards in downgaze and maintain rotational stability. In one aspect, the lenticular has a top surface, said top surface having a shape selected from the group consisting of flat, flat with rounded corners, concave, convex or tapered having a thicker portion closer to an edge of the contact lens, or combinations thereof. In another aspect, the lenticular is comprised of a plurality of lenticular sections. In yet another aspect, the lenticular is anatomically-shaped.

Abstract: A contact lens comprising one or more microchannels for transport of liquid through the lens is provided. The contact lens can be made by contacting a curable composition with a microfiber that is insoluble in the curable composition; curing the curable composition to provide a polymeric lens body with the microfiber embedded therein; and contacting the polymeric lens body with a solvent to dissolve the microfiber.

Abstract: A method of designing a fluid-filled contact lens (103) is described. The method involves generating a computational model that includes a fluid-filled lens (103) and the shape of a cornea causes deformation of an internal structure of the fluid-filled lens (103) to generate a deformed, fluid-filled lens (103) with altered optical properties. The method also includes modelling (5) the optical properties of the deformed, fluid-filled lens (103). The shape of the fluid-filled lens (103) is then adjusted (7) to reduce the effects of the deformation on the optical properties. This is referred to as an adjusted fluid-filled lens (103). A corresponding off-eye lens design is generated (110 based on the adjusted fluid-filled lens design.

Abstract: A WS12-releasing contact lens is described as well as method of manufacturing the same. The WS12-releasing contact lens comprises a polymeric lens body and WS12 releasably adhered to the polymeric lens body, and releases from 0.05 ?g to 0.5 ?g WS12 after 1 hour in a release media or when worn by a human subject. The WS12-releasing contact lens can be comfortably worn by a symptomatic contact lens wearer and can increase the duration of comfortable lens wearing time and/or reduce lens awareness events and/or reduce contact lens dryness in a symptomatic contact lens wearer.

Abstract: The present invention relates to a medicinal material for light therapy, comprising a matrix material and a photosensitizer, wherein the photosensitizer is dispersed inside the matrix material by copolymerization, is mixed inside the matrix material, or attached to the surface of the matrix material by surface grafting, modification, coating and the like. The present material can kill diseased tissue cells with a radiation under selected wavelength so as to obtain a phototherapy treatment of ophthalmic diseases. The present invention also provides a process for preparing the material and a use in preparing an ophthalmic medical device.

Abstract: The disclosure relates to a self-accommodating lens, which is formed in particular as a contact lens. The lens includes a lens body configured to be placed onto or into an eye of a patient. A plurality of actuators are arranged in a star-shaped manner on the front side of the lens body. The angle to an adjacent lens is determined by detection of a directional radio signal.

Abstract: A contact lens includes a central region, an annular region and a peripheral region. The central region includes a central point of the contact lens. The annular region symmetrically surrounds the central region. The peripheral region symmetrically surrounds the annular region. The peripheral region includes at least one color pattern portion. The annular region includes at least one power of critical point.

Abstract: A contact lens having dimples on a posterior surface is described as well as cast molds and injection molding inserts for manufacturing the same. The contact lens includes a posterior surface having an optic zone, a peripheral zone, and a circumferential edge, where dimples are located in the peripheral zone, and can include at least 1000 dimples.

Abstract: A method comprises: disposing a measurement contact lens upon an eye of a user; capturing at least one image of the eye and the measurement contact lens with an image sensor while the measurement contact lens is on the eye of the user and the eye is illuminated; processing the at least one image to obtain a centration of the measurement contact lens on the cornea of the eye; processing the at least one image to obtain an angular orientation of the measurement contact lens on the cornea of the eye; and determining, based on the centration and angular orientation of the measurement contact lens on the cornea of the eye, at least one parameter of a first contact lens to be worn on the eye with display eyewear or a second contact lens to be worn on the eye without the display eyewear.

Abstract: A device and method for altering the appearance of any eyeglasses by generating and applying an eyewear appliqué. Users may alter the façade of eyeglasses without the cost of new glasses. Users may create a profile including a frame scan file from a camera or scanner and specific design elements to create a vector file that is processed by the appliqué application to produce an appliqué with alternative design elements. The appliqué application produces an appliqué from the scan file and user preferences. The appliqué is peeled from the release liner to and then pressed onto the user's frame to create the newly designed eyewear appliqué and custom look. The adhesive used in the production process allows the eyewear appliqués to be removed from frames and reapplied multiple times. The user can easily remove an eyewear appliqué by peeling and replacing it with another for an alternative look.

Abstract: Embodiments concern an intraocular implantable device operable comprising a disk-shaped body having a symmetry axis and which further comprises a light-transmissive portion and an opaque portion wherein the light-transmissive portion is decentered with respect to the symmetry axis.

Abstract: Multilayer contact lenses and methods of making the same are described. A contact lens (100) includes a lens assembly (103). The lens assembly (103) includes a plurality of flexible lens layers. A first layer (101) has a uniform or smooth anterior surface (106), and a second layer (102) has a structured posterior surface that includes one or more recesses (105). The anterior surface (106) of the first layer (101) and the structured posterior surface of the second layer (102) define a first cavity (107) for containing one or more components.

Abstract: A contact lens system includes a shared antenna electrode, an accommodation actuator to provide variable optical power, and a controller coupled to the accommodation actuator and the shared antenna electrode. The controller including logic for arbitrating access to the shared antenna electrode between an impedance sensor and a communication circuit; selectively establishing an oscillator with the impedance sensor and the shared antenna electrode; correlating an oscillation condition of the oscillator to an accommodation setting; and adjusting the variable optical power of the accommodation actuator based upon the accommodation setting. An impedance across the shared antenna electrode varies based upon an amount an eyelid overlaps the contact lens system when the contact lens system is worn on an eye.

Abstract: An ocular lens may include a lens body including a first surface. The first surface may include a first zone including a plurality of friction reduction structures arranged in alignment with the movement of a user's upper eyelid during blinking. The first surface may also include a second zone including a plurality of friction reduction structures arranged in alignment with the movement of a user's lower eyelid during blinking.

Abstract: Contact lens packages are provided and each includes a base member having a cavity and a sealing member coupled to the base member. An unworn contact lens is provided in a packaging solution within the sealed cavity. The base member is a thermoplastic or other recyclable material. The base member includes at least one connecting member that can be an interlocking feature and/or a stackable feature. The connecting member is configured to connect to the connecting member of another base member, after the contact lenses are removed from the cavities. A recyclable thermoplastic contact lens assembly is also provided that includes empty contact lens package base members stacked and connected together. A method of manufacturing contact lens packages and a method to recycle used contact lens package base members, such as by curbside recycling, are also provided.

Abstract: A pressure sensor system is provided. In another aspect, a wireless intraocular pressure sensor includes a deformable or stretchable inductor. A further aspect of an intraocular pressure sensing system includes a deformable inductor sized to contact an eye. Another aspect provides an organ pressure sending system including a passive inductor with a wavy, serpentine or undulating shape.

Abstract: A contact lens system for monitoring ocular diseases includes a smart phone camera and a nanostructured contact lens. The nanostructures can cause visible color shifts from optical reflection in response to a physical surface curvature change of the contact lens. The physical surface curvature change of the contact lens can be detected by visible color shifts on a range of about 8° at normal room light. An embodiment of the contact lens can detect a change in the diffraction angle of light passing through the lens. A change in the diffraction angle can be correlated with can indicate a change in a hydration level of the ocular surface and/or K+ ion concentration change.

Abstract: An ophthalmic lens, including: an optical portion having: a near portion with a near dioptric power for viewing near distance; and a distance portion with a distance dioptric for viewing a distance further than the near distance; with the near portion or the distance portion being centrally disposed, wherein a portion that is not centrally disposed is annularly disposed at an outer edge of the near portion or the distance portion, the near portion or the distance portion centrally disposed in the optical portion having a portion A in which power is intensified and then weakened when viewed in X direction from a center to a periphery, and having a portion A? in which power is intensified and then weakened when viewed in X? direction from the center to the periphery, which is an opposite direction to the X direction, and also included is a related technique thereof.

Abstract: A system for detecting defects in a contact lens material comprising: a camera having a lens and a digital image output for inspecting said lens suspended in saline solution, wherein said camera's digital image output includes only the image produced by light in a color spectrum corresponding to a portion of the spectrum of light produced by fluorescent emission of said lens material; a first Ultra violet light source to illuminate said lens and excite fluorescent emission therein; a first filter to filter the emitted light from the lens which is illuminated by Ultra violet light; and a computer having an associated memory, an input for accepting the digital image output from said camera, and an output representative of an analyzed digital image wherein said analyzed digital image includes visible indications of any imperfections detected in said lens material.

Abstract: The present invention relates to a coupling interface between a laser source and a tissue (2) to be treated, characterized in that the coupling interface comprises —a ring (3) including: ?a side wall (31), ?a proximal end (311) intended to come into contact with the tissue (2) to be treated, and ?a distal end (312) intended to receive the end of the laser source; —a window (32) transparent to a laser beam generated by the laser source, said window being mounted in a sealed manner on the distal end (312) of the ring (3) in such a way as to close the distal end (312) of the ring (3).

Abstract: A hardenable multi-part acrylic composition having at least two parts that react upon mixing to form a cement, such as bone cement, which hardens to a solid is described that includes storage stable liquid first and second parts, and optionally, further liquid parts. The parts react upon mixing to form a cement that hardens to a solid. The composition includes an acrylic monomer component and an initiator component in an amount effective to polymerize the acrylic monomer component when mixed and/or activated with it. The liquid first part comprises an aqueous dispersion of acrylic polymer particles and acrylic polymer beads. The polymer beads are at an equilibrium water content with the aqueous phase of the dispersion that generally has a viscosity between 10 and 10,000 centipoise. A twin barreled syringe, caulking gun or other cement mixing and delivery device and a method of producing the composition are also described.

Abstract: Various embodiments are generally directed to a surgical probe with shape-memory material, such as a probe with a set of light sources, for instance. Some embodiments are particularly directed to a cannula with a shape-memory material that is used to secure a window. In one or more embodiments, for example, an apparatus for surgical use may include a cannula with a shape-memory material in an austenitic phase. In some embodiments, the window may be positioned at an opening of the cannula when the shape-memory material is in a martensitic phase. In some embodiments, transitioning the shape-memory material from the martensitic phase to the austenitic phase secures the window in position at the opening of the cannula.

Abstract: An assembly comprising a pair of multifocal ocular implants, wherein each implant has a TFMTF curve, for a pupil of diameter less than or equal to 4 mm, preferably less than 3 mm, having a peak corresponding to the distance vision of the wearer, as well as an asymmetrical peak which spreads between intermediate vision and near vision without discontinuity; for a first implant, the TFMTF value is greater in intermediate vision than that of near vision; for the second implant, the TFMTF value is greater in near vision than that of intermediate vision; the rising edge of the asymmetrical peak of the first implant has, as an absolute value, a mean slope greater than that of its falling edge, whereas the rising edge of the asymmetrical peak of the second implant has, as an absolute value, a mean slope less than that of its falling edge.

Abstract: An ophthalmic lens for treating myopia comprising: a base lens with a front surface, a back surface, and a first power profile selected to correct or substantially correct for a distance refractive error of the eye; one or more myopia control elements on at least one of the front and back surfaces of the lens; a first viewing region having a dimension selected based, at least in part, on a concentration of a pharmaceutical agent for use in conjunction with an ophthalmic lens, the first viewing region being configured to minimize, reduce and/or eliminate vision disturbances for distance vision; and a second viewing region comprising a power profile that is relatively more positive compared to the first viewing region; wherein at least one of the size of the second viewing region and the relatively more positive power of the second viewing region is selected based, at least in part, on the concentration of the pharmaceutical agent.

Abstract: An object of the present invention is to provide an imprinting curable composition which includes a silicon-containing polymerizable compound such as polysiloxane, exhibits outstanding adhesion to a substrate and excellent demoldability from a fine pattern mold, and causes very little mold contamination. The object is attained by providing a photo-imprinting curable composition including a polymerizable compound (A) containing a silicon atom in the molecule, a photopolymerization initiator (B) and an additive (C), the additive (C) being a compound represented by the following formula (C1) or (C2): R1OC2H4OnX1??(C1) X2OC2H4OpC3H6OqC2H4OrX3??(C2) (In the formula (C1), R1 is a C12-30 alkyl group, X1 is a hydrogen atom or an acyl group, and n is an integer of 0 to 50. In the formula (C2), X2 and X3 are each independently a hydrogen atom or an acyl group, and p, q and r are each independently an integer of 1 to 50).

Abstract: A method of manufacturing a 3-dimensional variable refractive-index optical-element with surface figure, the method comprising: depositing a plurality of nanocomposite-inks comprising an organic-matrix with a nanoparticle filler dispersed within, and at least partially curing a portion of the nanocomposite-ink to form a nanocomposite slab that is at least semi-solid; transferring the nanocomposite slab to a press, the press having a die mold with at least a first surface figure; and actuating the press to compress the nanocomposite slab and impart the die mold's first surface figure onto the nanocomposite slab to form a nanocomposite optical-element.

Abstract: The present invention provides a water-soluble silicone macromer. The water-soluble silicone macromer has a general formula: E?(M1)x?(M2)y, wherein M1 is a repeating unit which is derived from a silicone containing monomer, M2 is a repeating unit which is derived from a first hydrophilic monomer, and E is an ethylenically unsaturated group. The amount of M1 is in a range of 30-60 wt % based on the total weight of the water-soluble silicone macromer, and the amount of M2 is in a range of 40-70 wt % based on the total weight of the water-soluble silicone macromer. A silicone hydrogel composition containing the water-soluble silicone macromer and a silicone hydrogel lens made of the silicone hydrogel composition are also provided herein.

Abstract: An eye-mountable device includes layer(s) of polymer material defining a body. The body includes a first side and a second side extending from a first end to a second end. The first side opposes the second side and curves inwardly toward the second side. The second side curves outwardly away from the first side. The body includes an anterior surface and a posterior surface extending from the first side to the second side and from the first end to the second end. The anterior side opposes the posterior side. The posterior surface has a concave shape. The device includes a substrate in the body including a mounting platform disposed proximally to a middle of the second side. The device includes, on the mounting platform, electronics that interact with a biological environment and monitor health-related information. The body may have a thickness profile that prevents the device from undesired movement.

Abstract: The present invention is a phakic intraocular lens for implantation between an iris and a crystalline lens. The phakic intraocular lens includes a diffraction grating 5 disposed in a lens central part 2 and having circular, coaxial grooves formed thereon, and a support part 3 disposed outside the diffraction grating 5 and supporting the diffraction grating 5. A hole 6 is formed in the center of the diffraction grating 5.

Abstract: An augmented reality system can include an electronic contact lens and a power source. The source generates a time-varying magnetic field which induces a time-varying current in conductive coils embedded in the electronic contact lens. The electronic contact lens uses the induced current to harvest power or to determine the orientation of the contact lens. The embedded conductive coils are positioned such that the AR system can harvest power and estimate the orientation of the eye at a variety of contact lens orientations. The conductive coils may be embedded within the contact lens at any number of positions and orientations. The embedded coils can encircle a portion of the contact lens and can collectively form an annulus within the contact lens. The conductive coils are embedded such that for at least three conductive coils, no two of the planes defined by the at least three conductive coils are parallel.

Abstract: A corrective lens that can improve contrast sensitivity in a dark place, for example, at night is provided. When an axis in the anteroposterior direction passing through the geometric center of a lens is defined as the z-axis and a direction extending to the rear side of the lens is defined as the positive direction of the z-axis, a focal depth extension component represented by Ar3 (where r is the distance from the z-axis and A is a constant) is added to the z-coordinate value of a refractive surface determined based on a prescription power to increase the focal depth. The focal depth that decreases (shallows) in a dark place is increased to facilitate focusing on a target object located in front of or behind the original focal point. This can improve contrast sensitivity in a dark place.

Abstract: Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include a deformable inner portion and a deformable peripheral portion. When disposed over the optical region of an eye, the inner portion is configured so that engagement of the posterior surface against the eye deforms the posterior surface so that the posterior surface has a shape diverging form the refractive shape of the epithelium when viewing with the eye through the ophthalmic lens. The rigidity of the inner portion is greater than the rigidity of the peripheral portion and the ophthalmic lenses are configured to allow movement relative to the eye upon blinking of the eye and to be substantially centered on the optical region of the cornea following the blinking of the eye. Methods of correcting refractive errors of an eye such as astigmatism or spherical aberration using the ophthalmic lenses are also disclosed.

Abstract: A method includes placing a contact lens over a cornea of an eye. The contact lens includes a central convex disc, a peripheral curved portion that extends radially from the disc, an annular groove formed in the disc on the posterior portion, and one or more apertures formed in the groove. A drug substance is placed over the anterior portion of the contact lens. The groove is in contact with the cornea and is a depot for the drug substance. The groove is in fluid connection with the anterior portion of the lens via the one or more apertures. The drug substance moves in an undiluted manner to the groove and the contact lens holds the drug substance in contact with the cornea, unaffected by blinking or tear exchange, facilitating enhanced bioavailability to the cornea of the drug substance.

Abstract: An eye-mounted display includes a scleral contact lens with one or more femtoprojectors that project images onto the user's retina. The scleral contact lens has a non-circular perimeter, for example elongated along the direction of the eye opening. The non-circular shape can result in less slippage and/or rotation of the contact lens relative to the eye. If the contact lens is elongated (compared to traditional circular lenses), then it can contain conductive coils that enclose a larger area. Thus, the lens increases coupling efficiency for power or data transfer. There can also be more space within the contact lens for payloads.

Abstract: The present disclosure relates to keratoprosthesis apparatuses and methods of manufacturing keratoprosthesis apparatuses. The keratoprosthesis apparatus includes a circular backplate including a central aperture extending through the backplate from a face of the backplate to a posterior surface of the backplate. The circular backplate has a dome shape and comprises a plurality of spaced apart elongated slits extending radially outwardly from a central portion of the backplate. The plurality of spaced apart elongated slits surround the central aperture and extending through the backplate from the face of the backplate to the posterior of the backplate.

Abstract: A system and method for additively manufacturing a component including features for part identification are provided. The method includes selectively depositing a contrast agent on a cross sectional layer to define a component identifier of the component and directing energy from an energy source onto the contrast agent to fuse the contrast agent and the cross sectional layer. The contrast agent may be an x-ray emission contrast agent that is read using an x-ray emission spectroscopy method, an infrared contrast agent that is read using an infrared camera or an infrared scanner, or a radioactive contrast agent that is read using a gamma ray spectrometer.

Abstract: An ophthalmic lens that includes a lens material having two opposing curved surfaces, the curved surfaces defining a lens axis; and a light scattering region surrounding a clear aperture. The clear aperture and the light scattering region are substantially centered on the lens axis, and the light scattering region has a plurality of spaced apart scattering centers (e.g., on a lens surface and/or embedded in the lens material) sized and shaped to scatter incident light, the scattering centers being arranged in a pattern that includes a random variation in spacing between adjacent dots and/or a random variation in dot size.

Abstract: Contact lenses incorporate high plus or add power profiles that at least one of slow, retard or preventing myopia progression and minimize halo effect. The lens includes a center zone with a negative power for myopic vision correction; and at least one treatment zone surrounding the center zone, the at least one treatment zone having a power profile that increases from an outer margin of the center zone to a positive power within the at least one treatment zone of greater than +5.00 D.

Abstract: Contact lenses incorporate high plus or add power profiles that at least one of slow, retard or preventing myopia progression and minimize halo effect. The lens includes a center zone with a negative power for myopic vision correction; and at least one treatment zone surrounding the center zone, the at least one treatment zone having a power profile that increases from an outer margin of the center zone to a positive power within the at least one treatment zone of greater than +5.00 D.

Abstract: The invention is generally related to soft contact lenses which comprise a polyvinylalcohol-based hydrogel lens body and a durable lubricious coating thereon which are covalently attached to the polyvinylalcohol-based hydrogel lens body through 6-membered acetal rings and to a method for producing the same.

Abstract: An adapter for coupling a laser treatment device to an object for treatment. The adapter has an input side, which may be fixed relative to the laser treatment device, by a locking mechanism and which may be fixed to the object, for alignment of the object relative to the laser treatment device. A scanned laser beam is introduced on the input side, from the laser treatment device, along a beam path to the object with a reference structure. The reference structure lies on the beam path of the adapter and may be optically detected by means of the laser beam scanned over the region.

Abstract: Provided herein are synthetic antibacterial peptides that have a sequence at least 80% identical to a sequence shown in SEQ ID NO: 2 or the diastereomer thereof with a sequence shown in SEQ ID NO: 3 or pharmaceutical compositions thereof. Also provided are methods for stimulating wound healing via the synthetic antibacterial peptides and for forming an antimicrobial coating on contact lenses. In addition a device is provided that has a surface with a coating of the synthetic antibacterial peptides.

Abstract: A system of contact lenses includes at least two contact lenses, each lens having a visual correction for a non-rotationally symmetric eye aberration. Each lens has a different level or degree of a stabilization that is characterized by a thickness differential between a thickness of a stabilization zone and a thickness of a non-stabilization zone.

Abstract: An eye-mounted device includes a contact lens and an embedded imaging system. The front aperture of the imaging system faces away from the user's eye so that the image sensor in the imaging system detects imagery of a user's external environment. The optics for the imaging system has a folded optical path, which is advantageous for fitting the imaging system into the limited space within the contact lens. In one design, the optics for the imaging system is based on a two mirror design, with a concave mirror followed by a convex mirror.

Abstract: A contact lens includes a central region, an annular region and a peripheral region. The central region includes a central point of the contact lens. The annular region symmetrically surrounds the central region. The peripheral region symmetrically surrounds the annular region. The peripheral region includes at least one color pattern portion. The annular region includes at least one power of critical point.

Abstract: A lens for refractive tear shaping, having a curved lens body with a peripheral edge and a central opening therein. The central opening is shaped and sized and has a tear shaping edge structured to form a tear meniscus within the central opening. The tear meniscus being formed by interaction of a tear film of the eye and the tear shaping edge and having a posterior curvature conforming to an anterior corneal curvature and an anterior curvature. The anterior curvature is dependent on the size and shape of the central opening and structure of the tear shaping edge.

Abstract: An augmented reality (AR) system that enhances an AR participant's experience by providing a visual effect with added depth. The AR system displays previously achieved by an AR HMD are augmented with a second layer of accessible depth. This added depth is achieved by including, in the AR space/real world environment, external stereo screens upon which 3D stereo content is projected by one or more 3D projectors. The AR HMD is equipped with an external 3D screen viewing assembly so the AR HMD allows an AR participant wearing the AR HMD to view images on the external stereo screens in stereo. The external stereo screens can be used to produce 3D imagery that may differ in depth from the depth of the fixed focal length images displayed to the viewer by the AR HMD. The AR system enlarges the AR participant's simultaneous angular viewing range to 55 to 160 degrees.

Abstract: A variable geometry contact lens structure having a thickness t sufficient to carry an active payload is constructed using layers of materials with high oxygen transmissibility and low oxygen transmissibility. The low transmissibility layer provide mechanical support for the active payload, and the high transmissibility layers provide adequate oxygen transmission to the cornea of the user's eye. The ratio of the thicknesses of the two layers changes abruptly at the boundaries between the payload and non-payload regions of the structure. For example, at a boundary of the payload region, a ratio of thicknesses of the high transmissibility layer t1 to thickness of the low transmissibility layer t2, R=t1/t2, changes by at least 2:1 over a lateral distance of not more than t.

Abstract: A method for customizing active contact lenses, such as contact lens displays, for a plurality of wearers includes the following: Contact lens precursors are obtained for a plurality of wearers. The contact lens precursors include active electronics. The same contact lens precursors are used as a starting point to generate active contact lenses for many different individuals, but they are processed into active contact lenses that are customized for each individual wearer.

Abstract: A method and system of producing a digitally printed iris structure for an artificial eye by using suitable digital graphics software, the appearance of a dilating pupil/collarette is created within the combined center portion/inner ring area of a prosthetic eye—in that a pupil appears to dilate from a small diameter in bright light to a comparatively large diameter in dimmer or darker light. The process of creating such effect is a unique extension of the knowledge that certain colors and pigments in bright light are most apparent, and in dark light tend to appear grey to black.