Abstract: An image processing apparatus includes a calculation unit configured to calculate information indicating similarity among a plurality of tomographic images, and a generation unit configured to generate a tomographic image from the plurality of tomographic images based on the calculated information indicating similarity.

Abstract: The invention relates to an optical system for examining an eye by means of optical coherence tomography. The OCT system is designed in such a way that at least a first and a second state of the optical system can be selectively set by controlling the variable optical unit. In the first state, the OCT measurement beam has a measurement focus at an object distance from the objective, wherein the object distance has a value between 50 millimeters and 400 millimeters. In the second state, the measurement beam has defocusing at the same object distance, wherein the defocusing corresponds to a distance of a virtual or real focus from a position of the object distance that is greater than 100 millimeters.

Abstract: A scanning perimeter as disclosed herein comprises a first projection means projecting a first projection beam to uniformly illuminate a portion of a retina, said first projection beam passing through the pupil of the eye at a second separation region between a first crossing region, at which said illumination beam passes through the pupil, and a second crossing region of the pupil, at which light reflected by the retina passes through the pupil. A second projection means projects a second projection beam to project at least a fixation target on the retina, said second projection beam passing through the pupil at said first crossing region or said second crossing region. A third projection means projects a third projection beam to project at least a light stimulus on the retina, said third projection beam passing through the pupil at said first crossing region or said second crossing region.

Abstract: An optical measuring apparatus includes a first light source, a second light source and a switching unit. The first light source is used to emit a first light toward a first direction. The second light source is used to emit a second light toward a second direction. The switching unit selectively switches to a first mode or a second mode. When the switching unit switches to the first mode, it blocks the second light and let the first light emitted to an aiming region on eyeball to perform an optical aiming and determine an eye axis center position on the eyeball; when the switching unit switches to the second mode, the switching unit changes the second light from the second direction to the first direction to let the second light emitted to the eye axis center position on the eyeball to perform an optical measurement.

Abstract: An apparatus for motion compensated modelling of a parameter of an eye, comprising: a first measuring means for measuring a plurality of position parameters of the eye with respect to an optical reference coordinate system of the apparatus; a second measuring means for measuring an interference signal at a plurality of optical reference coordinates, wherein the measurement of the plurality of position parameters and measurement of the interference signal are time synchronized; means for correcting the interference signal to account for a displacements of a parameter of the plurality of position parameters; and means for modelling the eye parameter based at least in part on the corrected interference signal.

Abstract: In corneal crosslinking by applying a photoactivated crosslinking facilitator such as riboflavin to the cornea and irradiating the cornea with light, the cornea is contacted with a liquid (33) containing a source of oxygen during irradiation. The liquid transfers oxygen to the cornea to facilitate crosslinking.

Abstract: The present invention relates to a system, device and a method for objective visual field testing and in particular, to such a system and method in which provides objective chromatic perimetry test or color vision test using a pupillometer.

Abstract: A quality control method for optometric measurements includes the following steps: (a) recording, via computer, a first record (14) that includes at least one first value of a first identifier (12), enabling identification of a glasses wearer (1), and at least one other value of another identifier (13) enabling identification of an optometric apparatus (15) on a first optometric measuring site (10); (b) carrying out at least one optometric measurement (16) of the wearer; (c) sending, to a second site (20), a digital measurement data set (18) including the optometric measurement result from step (b), the digital data set being linked, via computer, to the first record; and (d) digitally processing the optometric measurement result from the first record (14) on the basis of a digital data reference system (45) and the values of the respective identifiers of the glasses wearer and the optometric apparatus of the first record.

Abstract: A method of generating a reliable image of an iris for subsequent optical analysis leading to identification or authentication of a mammal. The method comprises directing point light sources towards the iris, capturing a gray scale image of the iris and reflections of the point light sources, deriving a two tone image from the gray scale image, generating an image containing the true boundaries of the pupil, determining boundaries of the iris and generating an image containing the true boundaries of the iris, and generating a final image of the iris from the image containing the true boundaries of the iris. This establishes a reliable image of the iris. The process may further comprise conducting an identification or authentication process based on optical analysis of the final image of the iris and comparison with a pre-established data corresponding to a person whose identity has been confirmed.

Abstract: Systems and methods are provided to measure reaction times and/or responses for head, eye, eyelid movements, and/or changes in pupil geometry. The system includes eyewear or headwear including one or more eye-tracking cameras for monitoring the position and geometry of at least one eye and its components of the user, one or more scene cameras for monitoring the user's surroundings, and one or more processors to determine reaction times. Optionally, the system may include one or more of a multi-axis accelerometer to monitor head movements, light sources to trigger visual evoked responses, and/or electronic inputs that may be used to indicate the time of occurrence of external reference events. Measured reaction times and other measurements may be monitored for use in a range of applications. Responses and reaction times may be measured continuously over extended periods, even over a lifetime to measure consequences of the aging process.

Abstract: The present invention relates to a contact lens assembly and to an ophthalmic treatment apparatus comprising same. The contact lens assembly according to the present invention comprises: a housing arranged on the cornea of an eyeball so as to guide the treatment beam radiated onto the eyeball; and a reflection unit arranged inside the housing so as to radiate the treatment beam guided to the inside of the housing to a plurality of irradiation points along the outer circumferential direction of the eyeball around the pupil of the eyeball.

Abstract: A portable device for the optical signal transmission from and to the human eye, in which it is proposed that a rod-shaped housing (1) is provided, on the two end regions of which at least one emitter (3) and/or detector of electromagnetic waves is arranged and which has a holding clamp (2) in its middle region, wherein a power supply for the respective at least one emitter (3) and/or detector as well as a control unit (8), which is connected to the at least one emitter (3) and/or detector, are provided within the rod-shaped housing. The invention provides a portable device for the optical signal transmission from and to the human eye, which can be worn with a high wearing comfort in a discreet manner in the vicinity of the head and, and in particular allows the device to be worn in parallel with commercially available spectacles. Furthermore, the handling, storage and transport of corresponding devices are greatly facilitated.

Abstract: Systems, devices, media, and methods are presented for segmenting an image of a video stream with a client device, binarizing an area of interest within one or more image, identifying an initial pupil location and an initial iris radius, and determining a final pupil location and a final iris radius. Some embodiments enable the client device to perform one or more operations within a user interface based on the image segmentation.

Abstract: A mechanism is described for facilitating eye torsion-based accurate eye tracking on computing devices according to one embodiment. A method of embodiments, as described herein, includes determining a head pose representing a tilt of a head of a person in an image captured by a capturing device of one or more capturing/sensing device. The image may illustrate one or more eyes of the person. The method may further include estimating a gravity vector relating to an eye of the one or more eyes based on data relating to the image and sensed by a sensing device of the one or more capturing/sensing devices, computing a total torsion angle based on one or more of the head pose and the gravity vector, and estimating a gaze vector associated with eye to facilitate tracking of the eye. The tracking may include positions or movements of the eye based on the gaze vector.

Abstract: An image pickup apparatus capable of determining a light amount change characteristic at the time of photographing with high accuracy. A light amount change period of light from a photometric target is determined, based first and second evaluation values calculated, respectively, based on a predetermined photometric value, and each of photometric values at first and second intervals causing the photometric values to be in the same phase relationship and the opposite phase relationship with the predetermined photometric value, respectively, in a case where the light from the photometric target changes at a predetermined frequency. It is determined whether or not the light from the photometric target changes at a light amount change period corresponding to the predetermined frequency.

Abstract: The invention provides an apparatus and method for illuminating, imaging and treating the retina of an eye. The apparatus (10) comprises an illuminating device (16) including a planar light source capable of producing light in a plane, such that the illuminating device (16) is capable of illuminating a circumferential line on the retina (12) and a support structure, wherein the illuminating device (16) is pivotably mountable to the support structure and is rotatable about an axis (18) which lies substantially on the plane defined by the light source, such that, in use, the illuminating device (16) may be rotated about the axis (18) to illuminate an area of the retina (12).

Abstract: Systems and methods are provided for post-hoc correction of calibration errors in eye tracking data, which take into consideration calibration errors that result from changes in user position during a user session in which the user's fixations on a display screen are captured and recorded by an eye tracking system, and which take into consideration errors that occur when the user looks away from a displayed target item before selecting the target item.

Abstract: According to one or more embodiments, the processes and systems disclosed allow for displaying objects on a screen at a desired visual angle, and more particularly, in one aspect, to systems and methods for displaying optotypes during an eye examination.

Abstract: A system and method for measuring a characteristic of an eye of a subject receive data pertaining to the subject; assign the subject to an assigned age category based on the data pertaining to the subject; adjust a brightness level of a fixation target according to the assigned age category for the subject; provide the fixation target for a subject to view; and objectively measure at least one characteristic of the eye of the subject while the subject views the fixation target at the adjusted brightness level.

Abstract: A head mounted compact goggle based video oculography system is configured for use in VOG-based neuro-otologic testing. The system comprises: a goggle base surrounding the subject's eyes; an angled hot mirror within the goggle base; at least one digital camera attached to the goggle base along the top side of the goggle base taking images of at least one of the subject's eyes via a hot mirror reflection; an integral display for selectively displaying visual stimulus to the subject through the hot mirror and attached to the goggle base along the rear side of the goggle base; a controller coupled to the display generating each visual stimulus for each neuro-otologic test to be displayed to the subject via the display and coupled to each digital camera and receiving and storing data signals there from, the controller configured to calculate eye related data from the digital camera images during each neuro-otologic test, and configured to display the eye related data to users.

Abstract: The slit lamp microscope comprises: a supporting base capable of precisely horizontally moving with respect to a frame; a supporting section extended upward from the supporting base; a slit light unit attached to a front end part of the supporting section, the slit light unit accommodating a slit lamp which emits a slit light downward; a mirror unit attached to a vertical middle part of the supporting section, the mirror unit having a reflecting mirror, which reflects the slit light from the slit light unit toward an eye of an examinee; and a microscope unit for observing the eye of the examinee. A slit lamp power cable, which supplies electric power to the slit lamp and which is extended from the supporting base, is provided in a hollow part of the supporting section and connected to the slit lamp in the slit light unit without being exposed outside.

Abstract: The invention relates to a pair of spectacles (1) comprising a frame (2), said frame (2) having at least one lens-receiving opening (3) for a lens, and having a right nose section (5) of the frame and a left nose section (6) of the frame, wherein a right eye-capturing camera (7) is arranged in the right nose section (5) of the frame, and a left eye-capturing camera (8) is arranged in the left nose section (6) of the frame.

Abstract: An automated method for diagnosing and evaluating severity of retinopathy of prematurity in a retina of a patient is provided that is superior to conventional techniques. A graphical user interface (GUI) is provided for receiving biographical information for the patient creating a patient record in a database via the GUI. A photograph of the retina of the patient is collected and placed in the patient record via the GUI. The photograph is then analyzed to determine vascular distributions within the retina. A zone 1 boundary is assigned to the retina based on a set of threshold levels with respect to the determined vascular distributions. A system for performing the automated method is also provided.

Abstract: In a process for optical coherence tomography a plurality of first OCT slice images, in each first slice image representing a different slice of an object, are recorded. Subsequently a reference figure that is representative of the three-dimensional contour of at least one structural feature of the object in a given three-dimensional coordinate system is ascertained by feature recognition of the at least one structural feature in the first slice images. Then a plurality of second OCT slice images, each second slice image representing a different slice of the object, are recorded. At least a fraction of the second slice images are displaced in the coordinate system until each second slice image is in feature overlap with the reference figure. Lastly, a set of three-dimensional OCT image data is generated at least from the feature-overlapped second slice images.

Abstract: Apparatus, systems and techniques for capturing, processing and generating digital ophthalmic images using conventional ophthalmic lenses. Certain embodiments processor implemented gesture-based control methods that provide for an eye care specialist to use a gesture-based imaging trigger to capture images of selected ocular structures through a traditional ophthalmic lens.

Abstract: The invention relates to a system and method for screening a patient for obstructive sleep apnea (OSA) using recordings of tracheal breathing sounds of both nose and mouth breathing in the upright and supine positions to compute characteristic features of the patient, the characteristic features being compared to the mean values of similar features of OSA and non-OSA training groups to classify a patient as OSA or non-OSA.

Abstract: A problem is, in a liquid crystal film in which an alignment layer and a liquid crystal composition layer having homogeneous alignment are formed on a support substrate, to improve adhesion between the alignment layer and the liquid crystal composition layer, and durability under a severe environment such as high temperature and high humidity. A solution is a non-liquid crystalline polymerizable compound having a radically polymerizable group and a cationically polymerizable group in a molecule is simultaneously used as an antistripping additive in a polymerizable liquid crystal composition layer having homogeneous alignment.

Abstract: The present disclosure is directed to lenses, devices, methods and/or systems for addressing refractive error. Certain embodiments are directed to changing or controlling the wavefront of the light entering a human eye. The lenses, devices, methods and/or systems can be used for correcting, addressing, mitigating or treating refractive errors and provide excellent vision at distances encompassing far to near without significant ghosting. The refractive error may for example arise from myopia, hyperopia, or presbyopia with or without astigmatism. Certain disclosed embodiments of lenses, devices and/or methods include embodiments that address foveal and/or peripheral vision. Exemplary of lenses in the fields of certain embodiments include contact lenses, corneal onlays, corneal inlays, and lenses for intraocular devices both anterior and posterior chamber, accommodating intraocular lenses, electro-active spectacle lenses and/or refractive surgery.

Abstract: According to the present disclosure, a state estimation device estimating a state of a monitoring target based on an involuntary eye movement of an eyeball of the monitoring target is provided. The state estimation device in the present disclosure includes a microsaccade information acquisition portion obtaining microsaccade information that includes a state of variation of a gaze angle when a microsaccade of the involuntary eye movement occurs, and a state estimation portion estimating the state of the monitoring target based on the microsaccade information.

Abstract: A method for manufacturing a corrective ophthalmic glasses lens personalized for a wearer, includes defining and digitally recording the configuration parameters of the lens, calculating modeling data of the refractive faces of the lens, and manufacturing the lens in accordance with the configuration parameters.

Abstract: Systems and methods for designing and implanting a customized intra-ocular lens (IOL) is disclosed. In one embodiment, a system includes an eye analysis module that analyzes a patient's eye and generates biometric information relating to the eye. The system also includes eye modeling and optimization modules to generate an optimized IOL model based upon the biometric information and other inputted parameters representative of patient preferences. The system further includes a manufacturing module configured manufacture the customized IOL based on the optimized IOL model. In addition, the system can include an intra-operative real time analyzer configured to measure and display topography and aberrometry information related to a patient's eye for assisting in proper implantation of the IOL.

Abstract: In accordance with an embodiment of the invention, there is provided a device and method for detecting an amyloid protein in an eye of a mammal. A method comprises illuminating the eye with a light source having at least one of a wavelength property, a polarization property or a combination thereof, each appropriate to produce fluorescence in at least an amyloid-binding compound when the amyloid-binding compound is bound to the amyloid protein, the amyloid-binding compound having been introduced to the eye and specifically binding to the amyloid protein indicative of the amyloidogenic disorder; and determining a time decay rate of fluorescence for at least the fluorescence produced by the amyloid-binding compound bound to the amyloid protein, the determining permitting distinguishing of the presence of the amyloid-binding compound bound to the amyloid protein in the eye based on at least the time decay rate.

Abstract: An ocular system for detecting ocular abnormalities and conditions creates photorefractive digital images of a patient's retinal reflex. The system includes a computer control system, a two-dimensional array of infrared irradiation sources and a digital infrared image sensor. The amount of light provided by the array of irradiation sources is adjusted by the computer so that ocular signals from the image sensor are within a targeted range. Enhanced, adaptive, photorefraction is used to observe and measure the optical effects of Keratoconus. Multiple near infrared (NIR) sources are preferably used with the photorefractive configuration to quantitatively characterize the aberrations of the eye. The infrared light is invisible to a patient and makes the procedure more comfortable than current ocular examinations. A lens system is used to remove any low order aberrations present in the patient's eye and improve the detection sensitivity of the system.

Abstract: Systems and methods for expanding the field-of-view of ophthalmic scanning devices are presented. An ophthalmic scanning device is designed such that the pivot point of the scanning optics is maintained at a fixed location in the pupil while the scanning optics are rotated about the eye to obtain imaging data over an increased field-of-view than can be achieved by the scanning optics alone. The rotation can be achieved using a singular rotational motion of the scanning optics about a rotational axes coincident with the scanning pivot point or can be achieved using a combination of rotational motion with a second motion either rotational or translational to maintain the scanning pivot point at the fixed location. Embodiments related to optical coherence tomography and scanning laser ophthalmoscopy are described.

Abstract: An ophthalmological apparatus includes a first acquiring unit configured to acquire a first eye fundus image of an eye to be examined on basis of return light from the eye to be examined having a corrected aberration of the eye to be examined, a second acquiring unit configured to acquire a second eye fundus image of the eye to be examined, an aligning unit configured to align the first eye fundus image and the second eye fundus image, and a region setting unit configured to set a candidate region of interest on basis of the alignment.

Abstract: Pupillometry systems for measuring one or more pupillary characteristics of a patient are shown and described. The puillometry systems include at least one camera for capturing image data of one or more pupils, at least one radiation source configured to project radiation to the one or more pupils, and a computer system in data communication with the at least one camera, the computer system having a processor and a non-transitory computer-readable storage medium. The non-transitory computer-readable storage medium includes computer-readable instructions for collecting and time stamping the image data, identifying and measuring the one or more pupils in the image data, processing the image data to produce measurement data of change in the one or more pupillary characteristics, and calculating a standardized output of measurement data for the one or more pupillary characteristics.

Abstract: A method for image registration includes the steps of: providing a computer and an imager; acquiring and processing a reference image frame including a plurality of reference strips; acquiring and correcting a target frame by the steps of: acquiring one or more target frame strips of the target frame; comparing the one or more target frame strips in real-time to one or more corresponding strips of the reference frame based on a calculated registration of a specific target frame strip from a previous target frame; correcting a registration of the one or more target frame strips; repeating steps until a last strip of the target frame; repeating the steps of acquiring and correcting a target frame until a last target frame is acquired; and saving processed image based on a plurality of corrected target frames to a non-volatile memory. A system to perform the method is also described.

Abstract: An image processing apparatus includes a calculation unit configured to calculate information indicating similarity among a plurality of tomographic images, and a generation unit configured to generate a tomographic image from the plurality of tomographic images based on the calculated information indicating similarity.

Abstract: A spectacle lens is disclosed. The disclosed lens provides a vision correcting area for the correction of a wearer's refractive error. The viewing correction area provides correction for non-conventional refractive error to provide at least a part of the wearer's vision correction. The lens has a prescription based on a wave front analysis of the wearer's eye and the lens can further be modified to fit within an eyeglass frame.

Abstract: A system for measuring the interpupillary distance of two eyes of a face using a device equipped with a display and a camera. For example, a guide marker (or guide markers) is displayed on a reflective display, and an image is captured using the camera when the reflection of the face is aligned with the guide marker. A stereo pair is created using the camera image and the reflection of the face on the display, and the interpupillary distance is determined by comparing the three-dimensional positions of the two eyes. The device is capable of calibration using a calibration object to detect the distance between the guide marker on the display and the camera. A facial recognition engine is employed in some cases to detect the eyes or other points on the camera image.

Abstract: The present disclosure describes an apparatus for testing to assess the cone photoreceptor pathway by determining the sensitivity of the cone photoreceptors. The test may be used to determine of a subject is suffering from, or is likely to suffer from, a disease state involving the fovea, parafovea, macula, neurological pathways used by these area to communicate with the visual processing centers in the brain and cone photoreceptors and/or ganglion cells. Using the novel cone photoreceptor sensitivity test and apparatus, the present disclosure shows that cone photoreceptor sensitivity in subjects with primary open angle glaucoma was decreased as compared to a control group (p=0.04). This cone photoreceptor sensitivity test is shown to have excellent repeatability, can be administered in a short time, does not require extensive subject instruction and meets other limitations required for application in a clinical setting.

Abstract: A compensation optical apparatus for obtaining and image of an object without reduction in image quality irrespective of aberration compensation, includes: a division unit for dividing a return beam from a measured object; an aberration measurement unit for measuring an aberration caused by the measured object, with a divided beam from the division unit; an aberration compensation unit for performing aberration compensation based on the aberration measured by the aberration measurement unit; a projection unit for projecting a beam obtained by the aberration compensation in the aberration compensation unit to the measured object; an acquirement unit for acquiring a value exhibiting a state of the measured object based on the return beam from the measured object, which is obtained by the beam projected from the projection unit; and a control unit for retreating the division unit from an optical path based on the value acquired by the acquirement unit.

Abstract: Optical coherence tomography (OCT) scan data of a subject is acquired over a region of interest which can include an optic disc or a macula of a retina. Layer boundaries of retinal layers are identified in the OCT scan data to facilitate measurements. In one aspect, a measurement related to ratio value between a total backscattered signal intensity of one or more target layers of the retina and a total backscattered signal intensity of one or more reference layers is computed on a location-by-location basis within a region of interest of the OCT scan data. Measurements can be collected, aggregated, analyzed, and displayed in connection with other information taken or derived from the OCT scan data.

Abstract: Optical coherence tomography (OCT) scan data of a subject is acquired over a region of interest which can include an optic disc or a macula of a retina. Layer boundaries of retinal layers are identified in the OCT scan data to facilitate measurements. In one aspect, a measurement related to ratio value between a total backscattered signal intensity of one or more target layers of the retina and a total backscattered signal intensity of one or more reference layers is computed on a location-by-location basis within a region of interest of the OCT scan data. Measurements can be collected, aggregated, analyzed, and displayed in connection with other information taken or derived from the OCT scan data.

Abstract: A corneal endothelial cell photographing apparatus for photographing an endothelial cell in the cornea of the examinee's eye includes an optical system, an image processor, and a display controller. The optical system includes an illuminating optical system for irradiating the cornea with illuminating light, and a light receiving optical system including a light detector and configured to receive reflected light from the cornea including the endothelial cell. The image processor analyzes each of endothelial cell images photographed at different positions on the cornea, and acquires an integrated analysis result by integrating the result of analysis of each of the endothelial cell images. The display controller displays the endothelial cell images simultaneously on a monitor with reference to an endothelial cell image photographed at a central portion of the cornea, and displays the integrated analysis result on the same screen as for the endothelial cell images.

Abstract: An adaptive optics apparatus includes an aberration measuring unit that measures an aberration caused by a subject's eye, the aberration being measured on the basis of returning light that returns from the subject's eye; an aberration correcting unit that performs aberration correction in accordance with the aberration measured by the aberration measuring unit; an irradiation unit that irradiates the subject's eye with light corrected by the aberration correcting unit; and an adjusting unit that maintains a correction characteristic of the aberration correcting unit when the subject's eye moves out of a predetermined area.

Abstract: An ophthalmological device, comprising an eye patch, a photovoltaic, and a battery, wherein said photovoltaic is interconnected to said battery.

Abstract: There is provided an apparatus for recording a depth profile of a biological tissue, in particular a frontal eye section of a human eye, according to the principle of optical coherence tomography, comprising a light source adapted to generate a bundle of light rays, an interferometer arrangement having a beam splitter device adapted to spatially separate the bundle of light rays into a reference beam and a measurement beam directed toward the tissue, a reference beam deflection device adapted to deflect the reference beam, a beam superpositioning device adapted to spatially superimpose the deflected reference beam onto the measurement beam deflected by the tissue into a superpositioned beam, and a detector arrangement for detecting information in the superpositioned beam associated with the difference of the optical path length of the reference beam and the measurement beam.

Abstract: Exemplary embodiments enable an enhanced direct-viewing optical device to include customized adjustments that accommodate various optical aberrations of a current user. Customized optical elements associated with an authorized current user are incorporated with the direct-viewing optical device to produce a specified change in optical wavefront at an exit pupil. Possible replacement optical elements may have refractive and/or reflective and/or diffractive and/or transmissive characteristics based on current performance viewing factors for a given field of view of the direct-viewing optical device. Some embodiments enable dynamic repositioning and/or transformation of replaceable corrective optical elements responsive to a detected shift of a tracked gaze direction of a current user. Replaceable interchangeable corrective optical elements may be fabricated for current usage or retained in inventory for possible future usage in designated direct-viewing optical devices.

Abstract: An adaptive optics apparatus includes an aberration measuring unit that measures an aberration caused by a test object, the aberration being measured on the basis of returning light that returns from the test object; an aberration correcting unit that performs aberration correction in accordance with the aberration measured by the aberration measuring unit; an irradiation unit that irradiates the test object with light corrected by the aberration correcting unit; and an acquiring unit that acquires information based on a transmittance of the test object on the basis of the aberration measured by the aberration measuring unit.