Fermentate Of Unknown Chemical Structure Patents (Class 424/115)
  • Publication number: 20110091406
    Abstract: A composition and method for protecting personal care components, advantageously labile active personal care components, from decomposition during high temperature drying, employing water-soluble hydrolyzed polysaccharide encapsulants. Also disclosed is an additive for a personal care composition comprising a personal care component that is at least partially encapsulated within a hydrolyzed polysaccharide encapsulant. Also disclosed is a method for protecting a composition containing labile biologically active particles which comprises encapsulating at least a portion of the biologically active particles within hydrolyzed polysaccharide particles, thereby protecting said portion of said biologically active particles.
    Type: Application
    Filed: December 23, 2010
    Publication date: April 21, 2011
    Inventors: James V. Gruber, Andrew P. Banham
  • Publication number: 20110086105
    Abstract: Described herein are methods for identifying novel nucleic acid regulatory elements and compounds that modulate the regulation of such elements. Also described herein are nucleic acid sequence identified as novel nucleic acid regulatory elements and host cells containing such nucleic acid regulatory elements in a vector.
    Type: Application
    Filed: May 17, 2010
    Publication date: April 14, 2011
    Inventors: Anthony Giordano, Paul S. Eder, Deborah Beach McGill, Gregg Johannes
  • Publication number: 20110044972
    Abstract: The present invention relates to a process for preparing a nutritional, therapeutic or organoleptic product by growing non-recombinant yeast under aerobic conditions, in a medium that includes crude glycerol, as one possible carbon source to produce a yeast product. The yeast product can be processed to obtain such nutritional, therapeutic or organoleptic products as yeast paste, yeast metabolites, carbohydrates, proteins, functional proteins, nucleotides, yeast autolysates, yeast extract, yeast cell walls, beta-glucans, mannans or a product derived from a mineralized yeast product.
    Type: Application
    Filed: January 16, 2009
    Publication date: February 24, 2011
    Applicant: BIO PROCESSING AUSTRALIA PTY LTD.
    Inventors: Robin Fieldhouse, Donald Finlay MacLennan, David Graham MacLennan, Mary Elizabeth MacLennan
  • Patent number: 7883697
    Abstract: The present invention relates to the use of compositions comprising receptor ligands obtainable by a process comprising fermenting a food material, comprising animal milk or vegetable proteins, with lactic acid bacteria to obtain a fermented food or feed material that comprises ligands of specific adrenoreceptors and/or serotonin receptors. The fermented food or feed material is useful e.g. for reducing and/or stabilizing heart rate in a mammal. It may furthermore be used for treatment and/or relief of erectile dysfunctions and for treatment and/or relief of benign prostate hypertrophy (BPH), in a mammal.
    Type: Grant
    Filed: September 5, 2005
    Date of Patent: February 8, 2011
    Assignee: CHR-Hansen A/S
    Inventor: Bénédicte Flambard
  • Publication number: 20110002911
    Abstract: The present invention relates to a method for fermenting natural products with salt and fermented extracts prepared thereby. The method comprises: adding a predetermined amount of salt to at least one of natural products, including medicinal herbs and cereals; naturally fermenting the salted material; and extracting the fermented salted material with a solvent. Accordingly, the method can prevent the growth of various bacteria, including putrefactive bacteria, E. coli and anaerobic bacteria, which are harmful to the human body, in the natural product, and it also can prevent the generation of bed smells in the natural product. The fermented extract prepared by the method has fewer side effects and is safer than fermented extracts prepared by conventional fermentation methods.
    Type: Application
    Filed: February 27, 2009
    Publication date: January 6, 2011
    Inventors: Jun Seong Park, Hye Yoon Park, Jin Young Lee, Eun Joo Kim, Il Young Kwak, Kyung Hee Suh, Duck Hee Kim, Han Kon Kim
  • Publication number: 20100330137
    Abstract: The present invention relates to a pharmaceutical or dietary composition containing Mangosteen (Garcinia Mangostana pericarp) and being characterized by high bioavailability. A process for the manufacture of this composition is a further object of the present invention. In particular, the present invention relates to a composition containing Mangosteen extract and oligosaccharides in an amount ranging from 5 to 50 w/w % with respect to the Mangosteen extract or a fermented Mangosteen product and to a process for obtaining thereof.
    Type: Application
    Filed: March 10, 2008
    Publication date: December 30, 2010
    Inventor: Mauro Mantovani
  • Publication number: 20100317518
    Abstract: Particular aspects provide methods for converting glucosinolate in a glucosinolate-containing plant material to glucosinolate breakdown products (GBPs), comprising: providing an amount of processed glucosinolate-containing plant material, the processed material being depleted of oil and glucosinolate converting enzyme activity by virtue of said processing; providing an amount of glucosinolate converting enzyme activity; mixing the processed material with the amount enzyme activity; hydrating the mixture; and incubating the hydrated mixture, wherein the glucosinolates are enzymatically converted to GBPs. Preferably, the processed plant material comprises a oilseed-derived seedmeal material (e.g., meadowfoam seedmeal) from which the oil has been removed by the processing (e.g., solvent extraction and/or heat treatment). In particular embodiments, the glucosinolate converting enzyme activity comprises at least one of a myrosinase activity and a nitrile-forming activity.
    Type: Application
    Filed: July 21, 2008
    Publication date: December 16, 2010
    Inventors: Jan F. Stevens, Stephen Machado, Ralph Reed, Michael S. Martinez
  • Publication number: 20100221238
    Abstract: Embodiments of the present invention relate to insecticidal Bacillus thuringiensis Cry1 and Cry2 polypeptides. Methods for using the polypeptides and nucleic acids of embodiments of the invention to synergistically enhance resistance of plants to insect predation are encompassed in embodiments of the present invention.
    Type: Application
    Filed: January 22, 2010
    Publication date: September 2, 2010
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E.I. DU PONT DE NEMOURS AND COMPANY
    Inventors: JOHN L. FLEXNER, DEIRDRE M. KAPKA-KITZMAN, LISA PROCYK, BRUCE STANLEY, JIANZHOU ZHAO
  • Publication number: 20100221239
    Abstract: This invention provides method for the treatment and prevention of Alzheimer's disease without noticeable side effects caused to patients, comprising administering an effective amount of Monascus-fermented product including Monascus powder and Monascus beverage. The Monascus powder and beverage are prepared through specific fermentation procedures disclosed and comprise monacolins, anti-inflammation agents and anti-oxidant compounds. The Monascus compositions are extracted from fermented red mold rice (RMR).
    Type: Application
    Filed: March 15, 2010
    Publication date: September 2, 2010
    Inventor: Tzu-Ming Pan
  • Patent number: 7785585
    Abstract: The present invention provides a composition which includes a sclareol or a derivative thereof, wherein the sclareol or a derivative thereof is bound by a glycoprotein matrix. The composition of the invention provides improved potency, stability and bioactivity characteristics of sclareol, or its derivatives.
    Type: Grant
    Filed: May 15, 2007
    Date of Patent: August 31, 2010
    Assignee: Avoca, Inc.
    Inventors: David Peele, Dilip Chokshi
  • Publication number: 20100209410
    Abstract: Fungicidal mixtures, comprising 1) a fungicidal strain (I) selected from a) the Bacillus substilis strain with NRRL Accession No. B-21661, and b) the Bacillus pumilus strain with NRRL Accession No. B-30087, or a mutant of these strains having all the identifying characteristics of the respective strain, or a metabolite produced by the respective strain that exhibits activity against plant pathogenic fungi, and 2) at least one chemical compound II, selected from the active compound groups A) to F): A) azoles; B) strobilurins; C) carboxamides; D) heterocyclic compounds; E) carbamates; F) other fungicides; in a synergistically effective amount, methods for controlling harmful fungi using compositions of components 1) and 2), the use of a component 1) with a component 2) for preparing such compositions, and also fungicidal agents and seed comprising such compositions.
    Type: Application
    Filed: September 16, 2008
    Publication date: August 19, 2010
    Applicant: BASF SE
    Inventors: Ulrich Schoefl, Maria Scherer, Egon Haden
  • Patent number: 7736885
    Abstract: The present invention relates to a process for producing arachidonic acid. In one embodiment, Mortierella sect. schmuckeri microorganisms are cultured in fermentation medium, preferably containing a component of a complex nitrogen source. Further disclosed is a food product which includes Mortierella sect. schmuckeri microorganisms or lipid isolated from such microorganisms to enhance the arachidonic acid content of the food product.
    Type: Grant
    Filed: July 24, 2007
    Date of Patent: June 15, 2010
    Assignee: Martek Biosciences, Inc.
    Inventor: William R. Barclay
  • Patent number: 7727524
    Abstract: The present invention provides a liquid seasoning, which brings on a sufficient salty taste although it has a low sodium concentration, and which exhibits for example a pharmacological effect such as an antihypertensive effect at a high level. The present invention relates to a liquid seasoning, which contains the following components (A) to (D): (A) 3.55% or less by weight of sodium; (B) 0.5% to 4.2% by weight of potassium; (C) more than 2% by weight of an acidic amino acid and/or more than 1% by weight of a basic amino acid; and (D) 0.05% to 10% by weight of a food material having an antihypertensive effect.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: June 1, 2010
    Assignee: Kao Corporation
    Inventors: Shigemi Tsuchiya, Youko Seo, Jun Kohori, Ryuji Ochiai, Atsushi Suzuki
  • Patent number: 7718171
    Abstract: Use of a composition obtainable by a process comprising fermenting a food material, comprising animal milk or vegetable proteins, with a lactic acid bacterium to obtain a fermented food material which comprises active components with heart rate reducing properties for the manufacture of a product for reducing the heart rate and/or the fluctuations in the heart rate of a mammalian.
    Type: Grant
    Filed: April 7, 2004
    Date of Patent: May 18, 2010
    Assignee: Chr. Hansen A/S
    Inventor: Bénédicte Flambard
  • Publication number: 20100047361
    Abstract: The invention relates to active principles which are capable of inducing the conversion of inactive TGFb-Latent into active TGFb. The invention relates in particular to the use of such an extract for the manufacture of a composition for increasing the concentration of active TGFb1 in the skin, notably in the dermis. The present invention also relates to the uses which are derived from said use, as well as to cosmetic or pharmaceutical compositions which comprise said extract.
    Type: Application
    Filed: November 6, 2009
    Publication date: February 25, 2010
    Applicants: BASF Beauty Care Solutions France S.A.S., Laboratoire de Dermocosmetique
    Inventors: Eric PERRIER, Cecile ALTOBELLI, Anne CLEMENT, Corinne REYMERMIER, Nabil ABDUL MALAK
  • Patent number: 7666409
    Abstract: The present invention provides a liquid seasoning, which brings on a sufficient salty taste although it has a low common salt concentration, and which exhibits for example a pharmacological effect such as an antihypertensive effect at a high level. The present invention relates to a liquid seasoning, which contains the following components (A) to (C): (A) 3.55% or less by weight of sodium; (B) 0.5% to 4.2% by weight of potassium; and (C) 0.1% to 10% by weight of a food material having an antihypertensive effect, wherein the remaining portion of the liquid seasoning excluding component (C) is adapted by incorporation of a substance other than component (C) to have a nitrogen content (D) of 1.6% or more based on the total weight of the liquid seasoning.
    Type: Grant
    Filed: November 14, 2005
    Date of Patent: February 23, 2010
    Assignee: Kao Corporation
    Inventors: Shigemi Tsuchiya, Youko Seo, Jun Kohori
  • Patent number: 7662401
    Abstract: The present invention relates to the cosmetic or pharmaceutical use of an extract of a nonfruiting nonphotosynthetic filamentous bacterium in a composition containing a cosmetically or pharmaceutically acceptable medium, as an agent increasing the endogenous synthesis of superoxide dismutase, in particular for preventing and/or limiting the formation of free radicals and/or removing the free radicals present in cells; in addition, the invention relates to a composition comprising at least one extract of Vitreoscilla filiformis and lycopene.
    Type: Grant
    Filed: May 17, 2007
    Date of Patent: February 16, 2010
    Assignee: L'Oreal
    Inventors: Yann Mahe, Alain Meybeck
  • Patent number: 7659098
    Abstract: A method of treating a plurality of byproducts generated in the process of producing alcohol using corn as a raw material, and making effective use of them, particularly as feed compositions. The method of treating byproducts generated in the process of producing alcohol from corn comprises a step of using a koji mold to ferment a mixture of at least one solid byproduct and a distillation residue generated in the process of producing alcohol, to produce a koji fermentation product.
    Type: Grant
    Filed: September 12, 2006
    Date of Patent: February 9, 2010
    Inventor: Masahiro Yamamoto
  • Publication number: 20090291071
    Abstract: The present invention provides a neutraceutical formulation having unexpected optimizing effects on the release of various gastric hormones and which acts unexpectedly and synergistically to inhibit various metabolic reactions such as oxidation and glycation of lipoproteins, especially LDLs. An enhancement in the release of gastric hormones optimizes the release of various gastric juices, gastric enzymes, and endocrine secretion levels of hormones that have key roles in the metabolism, digestion, assimilation of caloric and non-caloric nutrients, the storage of body fats, and appetite satiety. The present composition has further effects as an antioxidant formulation and as an enhancer and stabilizer of the activity of other antioxidants.
    Type: Application
    Filed: May 12, 2009
    Publication date: November 26, 2009
    Inventor: Richard L. Kozlenko
  • Publication number: 20090285794
    Abstract: The present invention refers to a non-antibiotic therapeutic strategy for inhibiting oro-gastro-intestinal infections and pathogens in general and particularly Heliobacter pylori adherence and colonization in the gastrointestinal channel and preventing or relieving associated oro-gastro-intestinal disease. The invention relates to methods and products based on an active cereal product or ferric quinate. The invention is also applicable to other oro-gastro-intestinal pathogens in both humans and animals.
    Type: Application
    Filed: February 13, 2008
    Publication date: November 19, 2009
    Inventors: Thomas Boren, Göran Hallmans, Per Aman
  • Publication number: 20090253666
    Abstract: The présent invention relates to a composition comprising sarsasapogenin or a plant extract containing it in order to improve the gêneral state of the skin and in particular to improve and/or embellish any part of the body showing a déficit in lipids. More particularly, the invention is directed to a cosmetic method to improve the figure, comprising the step of topically applying to the skin a cosmetic or dermopharmaceutical composition comprising sarsasapogenin to favour the expansion and/or the formation of the subcutaneous adipose tissue, and/or to favour the lipid synthesis in the epidermis.
    Type: Application
    Filed: July 31, 2007
    Publication date: October 8, 2009
    Applicant: SEDERMA
    Inventors: Karl Lintner, Claire Mas Chamberlin
  • Patent number: 7588759
    Abstract: The present invention provides a composition which includes a sclareol or a derivative thereof, wherein the sclareol or a derivative thereof is bound by a glycoprotein matrix. The composition of the invention provides improved potency, stability and bioactivity characteristics of sclareol, or its derivatives.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: September 15, 2009
    Assignee: Avoca, Inc.
    Inventors: David Peele, Dilip Chokshi
  • Publication number: 20090196867
    Abstract: The invention provides a method for treating fatigue and/or mood disorders and/or improving satiety and/or vitality in a subject in need thereof, comprising the step of administrating an effective amount of a soy kefir powder to said subject.
    Type: Application
    Filed: November 26, 2008
    Publication date: August 6, 2009
    Applicant: KCLM RESEARCH IN NUTRITION INC.
    Inventor: Stan Kubow
  • Publication number: 20090162344
    Abstract: In order to provide a method for culturing an immunopotentiator-containing organism having the experience of being eaten, inexpensively without requiring usage of a component derived from an animal, Acetobacter, Gluconobacter, Xanthomonas, Zymomonas or Enterobacter which is an edible gram-negative bacterium having an immunopotentiation function is cultured using a culture solution composed mainly of wheat or bean curd refuse. Thereby, Acetobacter can be obtained inexpensively and safely, and also a low molecular weight lipopolysaccharide which is the immunopotentiator can be obtained inexpensively and safely. Furthermore, no impurity derived from animal components is mixed.
    Type: Application
    Filed: November 28, 2006
    Publication date: June 25, 2009
    Applicants: GEN-ICHIRO SOMA, BIOMEDICAL RESEARCH GROUP INC.
    Inventors: Gen-Ichiro Soma, Chie Kohchi, Hiroyuki Inagawa, Takashi Nishizawa
  • Patent number: 7544363
    Abstract: The present invention discloses compositions derived from an isolated Bacillus species spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain, suitable for topical application to the skin or mucosal membranes of a mammal, which are utilized to inhibit the growth of bacterium, yeast, fungi, virus, and combinations thereof. The present invention also discloses methods of treatment and therapeutic systems for inhibiting the growth of bacterium, yeast, fungi, virus, and combinations thereof, by topical application of therapeutic compositions which are comprised, in part, of isolated Bacillus species, spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain.
    Type: Grant
    Filed: October 12, 2007
    Date of Patent: June 9, 2009
    Assignee: Ganeden Biotech, Inc.
    Inventor: Sean Farmer
  • Publication number: 20090142331
    Abstract: This invention provides a method for the isolation and identification of marine actinomycetes tentatively named MAR3A and MAR3B and the use of these groups as a source of new biologically active compositions including pharmaceuticals. The method includes specifics about where these microorganisms occur and their culture requirements. It also provides information describing characteristic DNA sequences that are used to identify members of this group and information demonstrating that members produce metabolites with significant activities in pharmaceutically relevant bioassays.
    Type: Application
    Filed: June 21, 2004
    Publication date: June 4, 2009
    Inventors: William H. Fenical, Paul R. Jensen
  • Patent number: 7541042
    Abstract: The present invention discloses compositions derived from an isolated Bacillus species, spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain, suitable for topical application to the skin or mucosal membranes of a mammal, which are utilized to inhibit the growth of bacterium, yeast, fungi, virus, and combinations thereof. The present invention also discloses methods of treatment and therapeutic systems for inhibiting the growth of bacterium, yeast, fungi, virus, and combinations thereof, by topical application of therapeutic compositions which are comprised, in part, of isolated Bacillus species, spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain.
    Type: Grant
    Filed: June 14, 2005
    Date of Patent: June 2, 2009
    Assignee: Ganeden Biotech, Inc.
    Inventor: Sean Farmer
  • Publication number: 20090123455
    Abstract: This invention relates to a slimming cosmetic composition containing at least one compound inducing the production of IL-6 by the adipocytes in the form of a mixture with an NPY antagonist and/or an ?2 antagonist and with an excipient for a cosmetic preparation.
    Type: Application
    Filed: October 28, 2008
    Publication date: May 14, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Pierre CASELLAS, Jean-Marie DEROCQ, Joelle GUESNET
  • Publication number: 20090081149
    Abstract: A fermentation product of soya bean extract, e.g. soya milk, provides conditioning benefits for skin, particularly moisturising benefits, namely increased moisture, and conditioning benefits for hair, particularly reduction of fly away behaviour and improved curl retention.
    Type: Application
    Filed: June 27, 2006
    Publication date: March 26, 2009
    Inventors: Stephen Watkins, Severine Lieurey
  • Patent number: 7407654
    Abstract: The invention relates to an antibiotic substances of microbial origin, arbitrarily denominated antibiotic GE 81112 factor A, factor B1 and factor B, which is produced by fermentation of Streptomyces sp. DSMZ 14386, the pharmaceutically acceptable salts and compositions thereof, and their use as an antibacterial agent having inhibitory activity versus susceptible microbes.
    Type: Grant
    Filed: October 4, 2002
    Date of Patent: August 5, 2008
    Assignee: Vicuron Pharmaceuticals, Inc.
    Inventors: Enrico Selva, Flavia Marinelli, Daniele Losi, Linda Cavaletti, Ameriga Lazzarini, Alessandra Marazzi
  • Patent number: 7297659
    Abstract: The present invention relates to a synergistic composition useful as plant and soil health enhancer, comprising urine, neem and garlic, individually or in all possible combinations, with the treatment showing it has the ability to stimulate accumulation of nutrients in the plant biomass, proliferation of plant growth promoting, phosphate solubilizing, abiotic stress tolerant and antagonists towards plant pathogenic fungi, control phytopathogenic fungi in the rhizosphere of plants, and enhances the total phenolic contents of the plants.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: November 20, 2007
    Assignee: Council of Scientific & Industrial Research
    Inventors: Chandra Shekhar Nautiyal, Sangeeta Mehta, Harikesh Bahadur Singh, Sunil Balkrishna Mansinghka, Suresh Haribhau Dawle, Naryan Eknath Rajhans, Palpu Pushpangadan
  • Patent number: 7256024
    Abstract: A novel tyrosyl diester antibiotic is obtained from fermentation of a recombinant strain of Streptomyces lividans designated Stretomyces lividans WD 15684 (ATCC-202143). The new antibiotic, designated tyrissamycin, exhibits antibacterial activity, particularly against gram-positive bacteria.
    Type: Grant
    Filed: November 18, 2004
    Date of Patent: August 14, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jingfang Q. Cutrone, Lyndon M. Foster, Kimberly D. Krampitz, Stephen W. Mamber, Grace A. McClure, Todd C. Peterson, Lisa C. Rupar, Katie A. Thompson
  • Patent number: 7090875
    Abstract: External skin preparations containing one or more members selected from among a fermentation product, which is obtained by treating a bean extract with a microorganism, vitamin A and its derivatives. By potentiating skin cells and accelerating the production of hyaluronic acid, these preparations exert effects of preventing and relieving skin roughness, improving keratin, moistening, and preventing and relieving skin tension failure and wrinkles, thereby efficaciously retarding skin aging.
    Type: Grant
    Filed: December 6, 2001
    Date of Patent: August 15, 2006
    Assignee: Kabushiki Kaisha Yakult Honsha
    Inventors: Kouji Miyazaki, Satoshi Yoshikawa, Ryoko Iizuka, Takashi Kinoshita, Naohito Saito, Katsuyoshi Chiba, Naomi Kondo
  • Patent number: 7070965
    Abstract: A group of specific branched-chain fatty acids, with significant anticancer effects on human and animals; methods of making using either chemical synthesis or biosynthesis methods; and methods of treating cancer.
    Type: Grant
    Filed: April 14, 1999
    Date of Patent: July 4, 2006
    Inventor: Zhenhua Yang
  • Patent number: 6942860
    Abstract: The present invention is directed to a method for producing a new nematocidal composition particularly useful against plant parasitic nematodes and also a process to prevent damage resulting from nematode infestation. The method for production of the composition involves heating a pH-adjusted fermentation broth of microorganisms to a temperature of at least about 100° C. for at least about 15 minutes. Preferably, the microorganism is Gibberella fujikuroi, Streptomyces erythraeus, Bacillus sphaericus, Bacillus thuringiensis or Fusarium moniliforme.
    Type: Grant
    Filed: February 4, 2003
    Date of Patent: September 13, 2005
    Assignee: Valent BioSciences Corporation
    Inventors: Prem Warrior, Daniel Feulner Heiman, Linda Anne Rehberger, Ronald Eugene Johnson, James Russell Hansen, Kevin Allen McVicker
  • Patent number: 6905692
    Abstract: The present invention discloses compositions derived from an isolated Bacillus species, spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain, suitable for topical application to the skin or mucosal membranes of a mammal, which are utilized to inhibit the growth of bacterium, yeast, fungi, virus, and combinations thereof. The present invention also discloses methods of treatment and therapeutic systems for inhibiting the growth of bacterium, yeast, fungi, virus, and combinations thereof, by topical application of therapeutic compositions which are comprised, in part, of isolated Bacillus species, spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: June 14, 2005
    Assignee: Ganeden Biotech, Inc.
    Inventor: Sean Farmer
  • Patent number: 6864231
    Abstract: A composition is provided that includes a biologically active compound bound by a glycoprotein matrix. A method is also provided for the manufacture of a composition of the invention. The glycoprotein matrix can be formed by permitting the growth of glycoprotein producing bacteria in the presence of the active ingredient. The composition of the invention provides a method for increasing the stability and bioactivity of the active ingredient. A method is also provided for administering an active ingredient to a host by utilizing a composition of the invention.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: March 8, 2005
    Assignee: Pharmachem Laboratories, Inc.
    Inventor: Dilip Chokshi
  • Patent number: 6855350
    Abstract: The present invention relates to the preparation of therapeutic compositions comprising of fermented soy extracts made with lactic acid bacteria and the optional addition of at least a yeast. The invention also relates to therapeutic uses of such extracts in promoting general health, improving the health of subjects, preventing and/or treating cancer, preventing infections, reducing the incidence of infections, treating infections, treating asthma, treating inflammation, modulating the immune system and treating immune disorders.
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: February 15, 2005
    Assignee: Microbio Co., Ltd.
    Inventor: Kung-Ming Lu
  • Patent number: 6855524
    Abstract: The invention concerns a method for producing exopolysaccharides by fermenting micro-organisms characterised in that it consists in carrying out the fermentation in a nutrient medium comprising at least a source of carbon available to the micro-organisms and at least a source of nitrogen, said source being derived from a fraction of carob seed.
    Type: Grant
    Filed: September 6, 2000
    Date of Patent: February 15, 2005
    Assignee: Danisco USA Inc.
    Inventors: Olivier Nore, Jean-Luc Simon
  • Patent number: 6852317
    Abstract: A novel antibiotic-producing Streptomyces sp. is provided that exhibits antifungal activity only on certain specific plant pathogens. Also provided is a method of treating or protecting plants from fungal infections comprising applying an effective amount of an antibiotic-producing Streptomyces sp. having all the identifying characteristics of NRRL Accession number B-30145. The invention also relates to fungicidal compositions comprising this novel Streptomyces strain and the antibiotics and metabolites produced by this strain either alone, or in combination with other chemical and biological pesticides.
    Type: Grant
    Filed: September 27, 2001
    Date of Patent: February 8, 2005
    Assignee: AgraQuest, Inc.
    Inventors: Lori Jo Lehman, Randy Jay McCoy, Caiyao Yuan, Denise Carol Manker, Jimmy Ensio Orjala, Pamela Gail Marrone, Jorge Isaac Jimenez Santamaria
  • Patent number: 6844182
    Abstract: This invention is directed to Bacillus mutants which produce a factor which potentiates the pesticidal activity of a Bacillus related pesticide, a chemical pesticide and/or a virus with pesticidal properties.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: January 18, 2005
    Assignee: Valent BioSciences Corporation
    Inventors: Helle Outtrup, William D. Lidster, Susan C. MacIntosh, Robert L. Starnes, Denise Carol Manker
  • Patent number: 6838083
    Abstract: The present invention provides a process for the preparation of antimicrobial compound ?-keto aliphatic acid ester, a novel, aliphatic, fatty acid derivative from Bacillus sp. IICT-001.
    Type: Grant
    Filed: March 18, 2002
    Date of Patent: January 4, 2005
    Assignee: Council of Scientific and Industrial Research
    Inventors: Annapurna Jetty, Dattatray M. Akkewar, Kondapuram Vijaya Raghavan
  • Patent number: 6838268
    Abstract: The present invention provides a process for the preparation of antimicrobial compound ?-keto aliphatic acid ester, a novel, aliphatic, fatty acid derivative from Bacillus sp. IICT-001.
    Type: Grant
    Filed: July 24, 2003
    Date of Patent: January 4, 2005
    Assignee: Council of Scientific and Industrial Research
    Inventors: Annapurna Jetty, Dattatray M. Akkewar, Kondapuram Vijaya Raghavan
  • Publication number: 20040228854
    Abstract: The present invention relates to a method of producing a novel chemical substance capable of inducing morphogenesis, promoting growth of marine foliate green alga that use the microorganisms, and a culturing media for alga containing these novel chemical substances.
    Type: Application
    Filed: January 30, 2004
    Publication date: November 18, 2004
    Inventor: Yoshihide Matsuo
  • Publication number: 20040208863
    Abstract: In the present invention, lactic acid bacteria produce soluble factors (such as peptides or proteins) that block inflammatory responses in a mechanism that depends on G proteins and is post-transcriptional to effectively block protein production or secretion by cells.
    Type: Application
    Filed: January 29, 2004
    Publication date: October 21, 2004
    Inventors: James Versalovic, Jeremy A. Pena, Eamonn Connolly
  • Publication number: 20040101525
    Abstract: Antimicrobial compounds from Bacillus subtilis for use against animal and human pathogens. A novel strain of Bacillus subtilis was isolated from the gastrointestinal tract of poultry and was found to produce a factor or factors that have excellent inhibitory effects on Clostridium perfringens, Clostridium difficile, Campylobacter jejuni, Campylobacter coli, and Streptococcus pneumoniae. The factor(s) retain full viability and antimicrobial activity after heat treatment. The invention provides a method of treatment of pathogenic microorganisms including C. perfringens.
    Type: Application
    Filed: November 27, 2002
    Publication date: May 27, 2004
    Inventors: Angeline Seah Huay Lin, Alex Yeow-Lim Teo, Tan Hai Meng
  • Patent number: 6733801
    Abstract: This invention relates to a use of a fermented Glycine max (L.) extract prepared by fermenting an aqueous Glycine max (L.) extract with at least one lactic acid bacteria together with at least one yeast, in enhancing Natural Killer (NK) cell activity. In particular, the fermented Glycine max (L.) extract can be used in preventing and/or treating a disease in which NK cell activation is implicated in a subject, such as cancer, infectious diseases and modulating the immune system.
    Type: Grant
    Filed: June 25, 2002
    Date of Patent: May 11, 2004
    Assignee: Microbio Co., Ltd.
    Inventor: Kung-Ming Lu
  • Patent number: 6733751
    Abstract: An animal-derived lipid is disclosed that is useful as a carrying agent for anti-microbial formulations. Pharmaceutical and other preparations including Emu Oil are also described as profoundly useful components in anti-bacterial, anti-fungal, and anti-viral treatments. This lipid material is extracted from the Emu (Dromais Novae-Hollandiae), an indigenous bird of Australia and New Zealand. The present invention also discloses therapeutic compositions comprising Emu Oil in combination with an extracellular product of Bacillus coagulans or Pseudomonas lindbergii strain, comprising a supernatant or filtrate of said culture suitable for topical application to the skin or mucosal membranes of a mammal, which are utilized to inhibit the growth of bacterium, yeast, fungi, virus, and combinations thereof. Additionally, the aforementioned therapeutic composition may also include an anti-microbial, anti-mycotic, and/or anti-viral agent.
    Type: Grant
    Filed: March 10, 2003
    Date of Patent: May 11, 2004
    Assignee: Ganeden Biotech, Inc.
    Inventor: Sean Farmer
  • Patent number: 6709683
    Abstract: This invention relates to a method of producing fermented extract to obtain composition that has inhibition action on bacteria infection. The fermented extract is prepared by symbiotic culture of yeast and lactic acid bacteria, removing microbial cells from the resultant culture solution and concentrating the prepared culture solution.
    Type: Grant
    Filed: August 16, 2002
    Date of Patent: March 23, 2004
    Assignee: Micorbio Co., Ltd.
    Inventor: Kung-Ming Lu
  • Patent number: 6683049
    Abstract: A method and composition for treating a patient suffering from a disease, disorder or condition and associated pain include the administration to the patient of a therapeutically effective amount of a neurotoxin selected from a group consisting of Botulinum toxin types A, B, C, D, E, F and G.
    Type: Grant
    Filed: January 24, 2000
    Date of Patent: January 27, 2004
    Assignee: Allergan, Inc.
    Inventors: K. Roger Aoki, Michael W. Grayston, Steven R. Carlson, Judith M. Leon