Extract Or Material Containing Or Obtained From A Multicellular Fungus As Active Ingredient (e.g., Mushroom, Filamentous Fungus, Fungal Spore, Hyphae, Mycelium, Etc.) Patents (Class 424/195.15)
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Patent number: 8226956Abstract: Topical compositions comprising extracts of Rhizomucor miehei that are substantially devoid of acid-protease activity and their use in treating dermatologic conditions, including reducing the appearance of signs of skin aging.Type: GrantFiled: February 15, 2012Date of Patent: July 24, 2012Assignee: Active Organics, Inc.Inventors: Michael Bishop, Elysiann Bishop, Glen Gillis
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Publication number: 20120183571Abstract: The present invention relates to the use of antrodia camphorata in the treatment of skin conditions, such as acne vulgaris, urticaria and eczema, allergic rhinitis, diabetes mellitus and its complications, cancer cachexia, hypercholesterolemia, gout in a subject in need of such treatment. The present invention is also directed to the use of antrodia camphorata in the prevention and treatment of oral cancer and arterial restenosis, in a subject in need of such prevention. The methods comprise the steps of: identifying a subject in need thereof, and administering to the subject a formulation comprising an effective amount of antrodia camphorata, whereby the symptoms in the subject are reduced or prevented. The composition can be a pharmaceutical composition or a nutraceutical composition.Type: ApplicationFiled: March 30, 2012Publication date: July 19, 2012Inventors: Chieh-Chou Yu, Cheng-Chung Wei
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Patent number: 8222232Abstract: Glucosamine, N-acetylglucosamine and ?-glucan compositions suitable for human or animal consumption or use are disclosed. The glucosamine, N-acetylglucosamine and ?-glucan compositions are derived from fungal biomass containing chitin. Various methods of producing glucosamine, N-acetylglucosamine and ?-glucan compositions are also disclosed.Type: GrantFiled: March 31, 2006Date of Patent: July 17, 2012Assignee: Cargill, IncorporatedInventors: Todd Anderson, Shuang Zhou, Bryson Bergerud, Lawrence E. Fosdick, Tzyy-Jan Han, Jess Vasina, Andrea Vanderhoff, James R. Trinkle, Brenda L. Ray, John A. Bohlmann
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Publication number: 20120141524Abstract: A preparation method for an ethanol extract of the fruiting body of Antrodia camphorata (EEAC) is provided. The preparation method includes steps of: (a) providing the fruiting body of A. camphorata (AC); (b) extracting the fruiting bodies with a first ethanol solution; and (c) obtaining EEAC. EEAC further can be sequentially extracted or fractioned by n-hexane, ethyl acetate and ethanol, and an n-hexane fraction (FC), an ethyl acetate fraction (FA) and an ethanol fraction (FB) respectively are generated. The growth inhibition and apoptosis induction of leukemia cell line HL 60 are effectively mediated by FA product, in which zhankuic acid A is the bioactive marker. The amount of triterpenoid in the fruiting body of AC can be determined by NMR and HPLC analysis.Type: ApplicationFiled: February 16, 2012Publication date: June 7, 2012Applicant: KAOHSIUNG MEDICAL UNIVERSITYInventors: Yang-Chang Wu, Mei-Chin Lu, Fang-Rong Chang, Ying-Chi Du, Tung-Ying Wu
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Publication number: 20120134976Abstract: An oral formulation as described herein can comprise pomegranate extract, panax ginseng extract, and c. sinensis, where each is present in an amount effective to counteract and/or prevent effects of aging in a subject when administered to the subject. The effects of aging can include age-related changes in gene expression.Type: ApplicationFiled: May 24, 2011Publication date: May 31, 2012Inventors: Angela Mastaloudis, Steve Wood, Richard Weindruch, Tomas Alberto Prolla, Jamie Louis Barger, Mark Bartlett, Scott B. Ferguson, Joseph Chang
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Publication number: 20120128711Abstract: A composition and methods of use are disclosed for prevention and control of inflammation and oxidative stress and various associated medical conditions, including PTSD, chronic depression and traumatic brain injury. A composition providing a phytonutrient and enriched mushrooms having enhanced Vitamin D and ergothioneine are disclosed. The combined use of an enriched mushroom and phytonutrient provide a synergistic effect on cellular longevity and/or cellular rejuvenation of subjects with both a normal and nutritionally deficient diets, improved tolerance to oxidative and/or inflammatory stress, and increased cellular longevity and/or cellular rejuvenation as a result of the neutralization of free radicals and prevention of chronic inflammation.Type: ApplicationFiled: February 1, 2012Publication date: May 24, 2012Applicant: TOTAL NUTRACEUTICAL SOLUTIONS, INC.Inventors: Marvin S. Hausman, Malli Rao Varanasi
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Publication number: 20120121642Abstract: Methods and compositions for reducing and/or inhibiting inflammation by topical application of dermatocosmetic compositions comprising effective amounts of extracts of Coriolus versicolor that have been hydrolyzed by an acid protease, preferably Rhizomucor miehei, and thereafter rendered substantially devoid of acid-protease activity.Type: ApplicationFiled: December 14, 2011Publication date: May 17, 2012Applicant: ACTIVE ORGANICS, INC.Inventors: Michael Bishop, Elysiann Bishop, Walter Smith, Glen Gillis
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Publication number: 20120124703Abstract: New and distinct varieties of higher Basidiomycetes mushrooms selected from Coprinus comatus HAI-1237 and Tremella mesenterica HAI-17 deposited under The Budapest Treaty with the Centralbureau voor Schimmelcultures (CBS) under Accession Nos. CBS 123401 and.Type: ApplicationFiled: March 10, 2010Publication date: May 17, 2012Applicant: PALMED TEVA LTDInventor: Solomon P. Wasser
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Patent number: 8178105Abstract: The invention provides a composition containing a fruit body of Agaricus blazei murill or an extract of the fruit body, and an amino acid constituting the ornithine cycle or a salt thereof, wherein the pharmacological activities of the fruit body of Agaricus blazei murill or the extract of the fruit body and the amino acid constituting the omithine cycle or the salt thereof are increased synergistically. Such a composition can contain a fruit body of Agaricus blazei murill or an extract of the fruit body, and an amino acid constituting the ornithine cycle or a salt thereof in 10-100 parts by weight per 1 part by weight of the fruit body or the extract.Type: GrantFiled: December 14, 2007Date of Patent: May 15, 2012Assignee: Kyowa Hakko Bio Co., Ltd.Inventors: Toshikazu Kamiya, Shun Kayahashi, Akio Shirai
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Publication number: 20120107344Abstract: A novel herbal extract, MF101, is effective in the treatment of symptoms of menopause.Type: ApplicationFiled: November 28, 2011Publication date: May 3, 2012Applicant: BioNovo, Inc.Inventor: Isaac Cohen
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Patent number: 8168197Abstract: Disclosed herein is a skin external composition for alleviating dry skin symptoms, which contains an extract of Scrophularia buergeriana Miq. as a main component and further contains an extract of Poria cocos Wolf, as well as the use thereof for skin-moisturizing cosmetics. The composition contains, as active ingredients, the Scrophularia buergeriana Miq. extract and the Poria cocos Wolf extract, which are prepared by extracting each of Scrophularia buergeriana Miq. and Poria cocos Wolf using water, ethanol, methanol, hexane, ethyl acetate or butanol.Type: GrantFiled: September 19, 2007Date of Patent: May 1, 2012Assignee: Amorepacific CorporationInventors: Han Sung Kim, Chan Woo Lee, Youn Joon Kim, Jee Eun Kim, Duck Hae Kim, Ih Seop Chang
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Patent number: 8168198Abstract: A therapeutic agent for treating polycystic ovary syndrome (PCOS), which exhibits few, if any, side effects, is effective at inducing ovulation, and is safely available for not only females who desire to bear children, but also for unmarried or young females. A therapeutic agent for polycystic ovary syndrome (PCOS) in which an extract of mushrooms is contained as the active ingredient thereof is used.Type: GrantFiled: August 4, 2009Date of Patent: May 1, 2012Inventors: Kunihiko Tominaga, Hideo Anzai, Cun Zhuang
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Patent number: 8168196Abstract: This invention is intended to discover a fraction having strong anti-influenza virus activity via M? activation in the Grifola frondosa extract or an active substance distributed therein to develop a simple and effective production method and to use such fraction for food and beverage products, pharmaceutical products, feeds or feed additives, and the like. This is realized by treatment of maitake mushrooms with a molecular sieve apparatus, such as an ultrafiltration apparatus or gel filtration apparatus, to isolate glycoprotein-containing fractions or sugar-protein complex-containing fractions having molecular weights of 30,000 to 100,000, so as to minimize the influence on substances having strong anti-influenza virus activity and contaminants.Type: GrantFiled: October 26, 2007Date of Patent: May 1, 2012Assignee: Yukiguni Maitake Co., Ltd.Inventors: Masataka Watanabe, Masahide Takeyama
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Publication number: 20120100175Abstract: This subject invention is directed to a method for inhibition of cancer cells, comprising administrating an effective amount of a compound of formula I (Sesquiterpene lactones, antrocin) or pharmaceutically acceptable salts thereof, together with a pharmaceutically acceptable carrier, wherein the cancer cells are selected from colorectal cancer cells, liver cancer cells, lung cancer cells or breast cancer cells.Type: ApplicationFiled: December 27, 2011Publication date: April 26, 2012Applicant: CHAOYANG UNIVERSITY OF TECHNOLOGYInventors: Yew-Min Tzeng, Tien-Shen Yang, Chi-Tai Yeh
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Patent number: 8158750Abstract: This invention provides compositions and methods for stimulating the immune system. Such methods include administering an extract, purified peptide-linked glucan or active component thereof from Coriolus versicolor. The methods are particularly useful for prophylactic and therapeutic treatment of secondary immunodeficiency, wherein the immunodeficiency is the result of an infection, a malignant neoplastic disease, an autoimmune disease, a protein losing state, an immunosuppressive treatment, surgery or anesthesia.Type: GrantFiled: November 22, 2005Date of Patent: April 17, 2012Assignee: The Chinese University of Hong KongInventors: Albert H. L. Chow, Kevin K. W. Chu
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Publication number: 20120082720Abstract: The present invention describes dietary compositions and methods of using such compositions to treat chronic viral infections, including hepatitis B and hepatitis C infections.Type: ApplicationFiled: January 11, 2011Publication date: April 5, 2012Inventor: Sam Poon Ang
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Publication number: 20120082719Abstract: The present invention describes dietary compositions and methods of using such compositions to treat chronic viral infections, including hepatitis B and hepatitis C infections.Type: ApplicationFiled: October 5, 2010Publication date: April 5, 2012Inventor: Sam Poon Ang
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Patent number: 8142792Abstract: Topical compositions comprising extracts of Rhizomucor miehei that are substantially devoid of acid-protease activity and their use in treating dermatologic conditions, including reducing the appearance of signs of skin aging.Type: GrantFiled: June 3, 2010Date of Patent: March 27, 2012Assignee: Active Organics, Inc.Inventors: Michael Bishop, Elysiann Bishop, Glen Gillis
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Publication number: 20120070414Abstract: The present invention utilizes extracts of the pre-sporulation (preconidial) mycelial stage of entomopathogenic fungi as insect and arthropod attractants and/or pathogens and can be employed to limit the zoonotic and plant diseases they transmit. The fungus can be cultivated on grain, wood, agricultural wastes or other cellulosic material and extracts can be made thereof. More than one fungus and substrate can be used in combination with one or more antimicrobial, antiprotozoal, antiviral, or genetically modified agents that result in reduced spread of contagions and lessens the damage they inflict on animals and plants.Type: ApplicationFiled: November 28, 2011Publication date: March 22, 2012Inventor: Paul Stamets
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Publication number: 20120058140Abstract: A topical composition according to the present invention for use in a skin care regimen that provides matrix metalloprotease (MMP) inhibiting activity, tissue inhibitor of metalloprotease (TIMP) inducing activity, and immediate and delayed antioxidative activity. Preferably, the topical composition comprises at least one MMP inhibitor, a TIMP inducing agent, Tremella fuciformis (snow fungus) extract, Camellia sinensis (green tea) leaf extract, and Eugenia caryophyllus (clove) extract. The compositions are useful in anti-wrinkle and anti-aging products, providing elasticity, firmness, tone and texture to the skin, ameliorating fine lines and preventing skin damage.Type: ApplicationFiled: September 2, 2010Publication date: March 8, 2012Applicant: Bath & Body Works Brand Management, Inc.Inventors: Joseph D. Ceccoli, Brian Costello, James A. Hayward, Konstantinos M. Lahanas
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Patent number: 8119141Abstract: This invention provides a method for identifying a composition of Cinnamomi and Poria. This invention further provides a composition comprising: Ramulus Cinnamomi, Poria Cortex, Moutan Radicis, Radix Paeonize Alba, and Semen Persicae. This invention provides various uses of these compositions.Type: GrantFiled: October 19, 2009Date of Patent: February 21, 2012Assignee: Jiangsu Kanion Pharmaceutical Co. Ltd.Inventor: Wei Xiao
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Publication number: 20120039928Abstract: The present invention relates to an extract of a processed herbal medicinal plant and a composition for skin external application which contains the extract. More specifically, the composition for skin external application contains an extract of processed herbal medicinal plant, prepared through a method comprising the steps of: (a) processing an herbal medicinal plant by a process of boiling, steaming, roasting, baking or heating the medicinal plant or a combination of two or more of these processes; (b) obtaining an extract of the processed medicinal plant. The composition shows an improved antioxidant effect.Type: ApplicationFiled: October 18, 2011Publication date: February 16, 2012Inventors: Jun Seong Park, Hye Yoon Park, Dong Hyun Kim, Eun Jeong Moon, Ji Hye Chung, Jae Kyoung Lee, Duck Hee Kim, Han Kon Kim
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Publication number: 20120039927Abstract: The invention provides methods for treating and/or preventing the recurrence of a senile cataract, and/or for inhibiting the development of a senile cataract and/or an incipient senile cataract, in a human or animal subject. The invention further provides nutraceutical compositions suited for the same, derived from an extract of truffles (Pezizaceae). The compositions comprise the extract in a therapeutically sufficient amount for the treatment and/or prophylaxis of a senile cataract in a human and/or animal subject.Type: ApplicationFiled: August 9, 2011Publication date: February 16, 2012Inventor: Arvin Morgan
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Publication number: 20120039976Abstract: The present invention utilizes extracts of the pre-sporulation (preconidial) mycelial stage of entomopathogenic fungi as insect and arthropod attractants and/or pathogens and can be employed to limit the zoonotic diseases they transmit. The fungus can be cultivated on grain, wood, agricultural wastes or other cellulosic material and extracts can be made thereof. More than one fungus and substrate can be used in combination with one or more antimicrobial, antiprotozoal, antiviral, and genetically modified agents that result in reduced spread of contagions and lessens the damage they inflict on animals, and plants.Type: ApplicationFiled: October 24, 2011Publication date: February 16, 2012Inventor: Paul Stamets
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Patent number: 8110228Abstract: A method of using an herbal extract of the a mixture of: Herba Scutellaria barbata, Radix Sophora subprostratae, Radix Anemarrhena, Semen Glycine sojae, Radix Glycyrrhiza, Rhizoma Rhei, Fructus Tritici levis, Radix Astragali, Radix Rehmania, Fructus Ligustri lucidi, Semen Zyziphi spinosa, Plumula Nelumbinis, Poria cocas, Rhizoma Alismatis, Cortex Moutan radicis, Fructus Corni, Radix Achyranthis, Concha Ostrea, Radix Aspargi, Radix Pueraria, Radix Atractylodis macrocephala and Herba Epimedium, for the treatment of hot flashes associated with menopause is disclosed herein.Type: GrantFiled: October 28, 2008Date of Patent: February 7, 2012Assignee: Bionovo, Inc.Inventor: Isaac Cohen
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Patent number: 8110230Abstract: Phytoceutical compositions for the prevention and treatment of circulatory disorders, feminine endocrine disorders, and dermal disorders. A specific combination of extracts of plants is taught, as well as principles for varying the formulations based on categorizing plants into one of three groups, Energy, Bio-Intelligence, and Organization and selecting several plants from each group. Such combinations have synergistic effects, with minimal side effects.Type: GrantFiled: February 12, 2010Date of Patent: February 7, 2012Inventor: Jose Angel Olalde Rangel
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Patent number: 8097258Abstract: Methods and compositions for reducing and/or inhibiting inflammation by topical application of dermatocosmetic compositions comprising effective amounts of extracts of Coriolus versicolor that have been hydrolyzed by an acid protease, preferably Rhizomucor miehei, and thereafter rendered substantially devoid of acid-protease activity.Type: GrantFiled: November 11, 2010Date of Patent: January 17, 2012Assignee: Active Organics, LPInventors: Michael Bishop, Elysiann Bishop, Walter Smith, Glen Gillis
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Publication number: 20120003261Abstract: The present invention provides methods of isolating cytotoxic metabolites from a fungus, and specific metabolites obtained from such methods. The present invention also provides methods of controlling fungal diseases in plants by treating the plants with cytotoxic metabolites as well as methods of treating cardiac arrhythmia in organisms in need of such treatment by administering the above-noted metabolites to such organisms.Type: ApplicationFiled: June 18, 2009Publication date: January 5, 2012Applicant: Temasek Life Sciences Laboratory LimitedInventors: Rajesh Narhari Patkar, Naweed Isaak Naqvi
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Publication number: 20120003262Abstract: Disclosed is a health food containing extracts of Phellinus linteus and vegetable worms for preventing and treating cancer. The health food contains ethanol extract of the mixture containing the mycelia of the Phellinus linteus and vegetable worms at a ratio of 1:5 to 5:1. The disclosed anticancer health food can enhance immunity and prevent cancer through the suppression and propagation suppression of cancer cells themselves. The suppression and reproduction rate suppression of the cancer cells themselves are achieved through the ingestion of the health food containing the Phellinus linteus and vegetable worms. Therefore, the disclosed anticancer health food can provide ideal treatment when being used with existing anticancer drugs.Type: ApplicationFiled: April 1, 2009Publication date: January 5, 2012Applicant: HAN KOOK SHIN YAK CO., LTD.Inventors: Ki Hwan Bae, Wen Yi Jin, Jae Kuk Yoo, Byeong Wook Park, Jin Pyo Kim, Ick Soo Lee
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Publication number: 20110305737Abstract: A comprehensive, single agent cosmetic cream or lotion containing a high number of ingredients that target anti-aging in a defined manner. The cream or lotion contains a high number and variety of active substances that demonstrate excellent safety and efficacy in all of the various defined categories of skin aging, including but not limited to wrinkles, abnormal pigment or brown spots due to aging of the skin and an unexpectedly high efficacy in the reduction of redness and acne and rosacea blemishes.Type: ApplicationFiled: June 7, 2011Publication date: December 15, 2011Applicant: NY Derm LLCInventor: Macrene Alexiades-Armenakas
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Patent number: 8071105Abstract: The present disclosure relates to the discovery of methods of isolating subfractions of an F3 Reishi extract, and of administration of these novel isolates to eukaryotic cells in order to induce certain immumodulatory, hematopoeitic and tumor-inhibiting phenotypic changes in those eukaryotic cells, mediated through particular toll-like receptor (TLR) and other transmembrane receptors. F3 subfractions F301 and F331 have demonstrated that F331 is capable of activating at least TLR-2 while F301 is capable of activating at least TLR-2, TLR-4, and TLR-5.Type: GrantFiled: October 2, 2008Date of Patent: December 6, 2011Assignee: Academia SinicaInventors: Shu-Mei Liang, Yen-Po Chen, Wen-Bin Yang, Chi-Huey Wong
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Patent number: 8062680Abstract: Phytoceutical compositions for the prevention and treatment of circulatory disorders, feminine endocrine disorders, and dermal disorders. A specific combination of extracts of plants is taught, as well as principles for varying the formulations based on categorizing plants into one of three groups, Energy, Bio-Intelligence, and Organization and selecting several plants from each group. Such combinations have synergistic effects, with minimal side effects.Type: GrantFiled: February 12, 2010Date of Patent: November 22, 2011Inventor: Jose Angel Olalde Rangel
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Publication number: 20110250226Abstract: A composition for promoting the proliferation of hematopoietic stem cells, which contains mushroom extracts, and more particularly to a composition and functional food for promoting the proliferation of hematopoietic stem cells, which contain, as active ingredients, an Inonotus Obliquus extract, a Ganoderma Luciderm extract, a Phellinus Linteus extract, and plant extracts promoting the immune activity-enhancing effects of these mushroom extracts. The composition and functional food assists in enhancing immune activity by significantly promoting the proliferation of hematopoietic stem cells, and shows positive effects on the increase in anticancer activity, anti-inflammatory activity and cell activity, the regeneration of damaged tissue and the prevention of cardiovascular diseases, through the proliferation of hematopoietic stem cells and the enhancement of immune activity.Type: ApplicationFiled: January 18, 2010Publication date: October 13, 2011Inventors: Hyung Suk Bae, Sung Keun Kang, Ii Seob Shin, Sang Kyu Woo, Yun Jung Kim, Mi Ae Kim, Jeong Chan Ra
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Publication number: 20110243970Abstract: Disclosed is a composition for the inhibition of transplant rejection and the treatment of skin diseases, comprising a cordyceps mycellia extract as an active ingredient. The cordyceps mycellia extract significantly suppresses the production of antibodies to transplants without side effects, such as weight change. Based on natural material, the composition is non-toxic and harmless to the human body and thus can be used as an immunosuppressant for organ transplantation. Also, it stops oozing from sores and is useful in the treatment of skin diseases, including atopy, allergic reactions, decubitus ulcers, pemphigus and smallpox.Type: ApplicationFiled: June 16, 2011Publication date: October 6, 2011Applicant: HANKOOK PHARM. CO., INC.Inventors: Man Woo HAN, Jae Kuk YOO, Chang-Uk HUR, Hwan-Chul KIM, Jin Pyo KIM
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Publication number: 20110223190Abstract: The present invention is generally directed to methods for the administration of compositions related to improved physical performance and post-exertion recovery, as well as the administered compositions. It is more specifically directed to compositions containing a FV extract and methods for using such compositions that, among other things, improve lactic acid clearance, muscle reaction time, stamina, exertion recovery time and reduce fatigue. In an extract aspect, the Flammulina velutipes extract has the following characteristics: a moisture content ranging from 0 percent to 10 percent; a protein content ranging from 20 percent to 40 percent; a carbohydrate content ranging from 40 percent to 80 percent; an ash content ranging from 0 percent to 15 percent; and, a fat content ranging from 0 percent to 5 percent.Type: ApplicationFiled: September 17, 2007Publication date: September 15, 2011Inventors: Edward Stephen Morrissey, Ruotao Wang
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Publication number: 20110206721Abstract: Dietary, health, and/or nutritional supplements provide various formulations of mushrooms grown in fermented soy, with or without rice flour, optionally in combination with sweetener(s), curcumin, and various other herbs and spices. Certain embodiments or compositions may be in liquid, beverage, solid, paste or powder forms. In certain embodiments the supplements contain mushroom species grown in fermented soy in the presence of certain bacterial species and optionally rice or rice flour. In some embodiments, other ingredients that may be present include one or more of curcumin, desmethoxycurcumin and bis-desmethoxycurcumin or all three curcumins. Certain embodiments may be used to treat or provide symptomatic relief from a variety of maladies ranging from malnutrition to mood related disorders to metabolic support and other more severe conditions as described herein.Type: ApplicationFiled: February 22, 2011Publication date: August 25, 2011Inventor: Vijaya Nair
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Publication number: 20110206722Abstract: A pharmaceutical composition includes Folium Isatidis 10-30 parts, Semen Cassiae 15-35 parts, Flos Inulae 10-20 parts, Flos Carthami 15-30 parts, Flos Chrysanthemi 10-30 parts, Herba Apocyni Veneti 20-50 parts, Ginkgo flavone 20-40 parts, emodin 20-35 parts, crataegin 30-50 parts, gypenoside 15-55 parts, Panax Notoginsenoside 20-60 parts. This composition can improve the level of high density lipoprotein in blood, clean up blockage of vein, soften vein, and reduce viscosity of blood.Type: ApplicationFiled: November 28, 2008Publication date: August 25, 2011Inventors: Zhizheng Du, Jiankui Tang
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Publication number: 20110206720Abstract: The present invention is related to the usage of Antrodia cinnamomea fruit body derivatives. The fruit body derivatives comprise acetic acid extract, acetic ether extract and Antrocamphin A. The acetic acid extract, acetic ether extract and Antrocamphin A can reduce the expression of iNOS and COX-2 and therefore inhibit the production of pro-inflammatory molecules.Type: ApplicationFiled: February 23, 2010Publication date: August 25, 2011Applicant: Taiwan Leader Biotech CorpInventor: Sheng-Yang WANG
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Publication number: 20110200551Abstract: The present invention utilizes extracts of the pre-sporulation (preconidial) mycelial stage of entomopathogenic fungi as insect attractants and/or pathogens. The fungus can be cultivated on grain, wood, agricultural wastes or other cellulosic material. More than one fungus and substrate can be used in combination.Type: ApplicationFiled: April 18, 2011Publication date: August 18, 2011Inventor: Paul Edward Stamets
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Publication number: 20110189220Abstract: The present subject matter relates to a novel mushroom composition and methods for making and using the same. In one aspect, the subject matter involves a composition comprising a combination of mushrooms or components derived from mushrooms selected from the group consisting of Reishi Ganoderma lucidum, Reishi Ganoderma lucidum, Cordyceps sinensis, Maitake Grifola frondosa, Shiitake Lentinula edodes, Poria cocos, Lion's Mane Hericium erinaceus, Mesima Phellinus linteus, Turkey Tail Coriolus Tramentes versicolor, Chaga Inonotus obliquus, and Chaga Inonotus obliquus. In some embodiments, the present subject matter relates to methods for modulating immune function, regulating the activity of lipoxygenases and cyclooxygenases, improving cardiovascular health, and/or inhibiting cell proliferation diseases and disorders. In one embodiment the composition provides a balancing of anti-inflammatory and pro-inflammatory function in an animal, including in humans.Type: ApplicationFiled: January 28, 2011Publication date: August 4, 2011Applicants: NEW CHAPTER INC., BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Peiying YANG, Robert NEWMAN, Paul SCHULICK
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Publication number: 20110177113Abstract: The present invention relates to the use of antrodia camphorata in the treatment of skin conditions, allergic rhinitis, diabetes mellitus and its complications, cancer cachexia, hypercholesterolemia, gout in a subject in need of such treatment. The present invention is also directed to the use of antrodia camphorata in the prevention and treatment of oral cancer and arterial restenosis, in a subject in need of such prevention. The methods comprise the steps of: identifying a subject in need thereof, and administering to the subject a formulation comprising an effective amount of antrodia camphorata, whereby the symptoms in the subject are reduced or prevented. The composition can be a pharmaceutical composition or a nutraceutical composition.Type: ApplicationFiled: January 19, 2010Publication date: July 21, 2011Inventor: Chieh-Chou Yu
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Publication number: 20110173727Abstract: The invention provides methods for preparing a conifer seedling with increased tolerance to a pest. A conifer seedling is inoculated with an isolated endophyte when the conifer seedling is susceptible to colonization by the endophyte.Type: ApplicationFiled: October 24, 2007Publication date: July 14, 2011Applicant: J.D. IRVING, LIMITEDInventors: John David Miller, Greg William Adams
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Publication number: 20110129491Abstract: Methods and compositions for reducing and/or inhibiting inflammation by topical application of dermatocosmetic compositions comprising effective amounts of extracts of Coriolus versicolor that have been hydrolyzed by an acid protease, preferably Rhizomucor miehei, and thereafter rendered substantially devoid of acid-protease activity.Type: ApplicationFiled: November 11, 2010Publication date: June 2, 2011Applicant: Active Organics, Inc.Inventors: Michael Bishop, Elysiann Bishop, Walter Smith, Glen Gillis
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ANTI-CANCER ACTIVE SUBSTANCE FROM ANTRODIA CAMPHORATA, METHOD FOR PREPARING THE SAME AND USE THEREOF
Publication number: 20110123562Abstract: An anti-cancer active substance from Antrodia Camphorata, produced from mycelium of Antrodia Camphorata by following steps: (1) culturing mycelium of Antrodia Camphorata by liquid fermentation; (2) extracting the thus-obtained mycelium with ethanol and concentrating the extracted solution to obtain an ethanol extract; (3) dissolving the ethanol extract in water, and extracting with equal volume of ethyl acetate to obtain ethyl acetate extract; (4) purifying the ethyl acetate extract by silica gel column chromatography using hexane/ethyl acetate gradient as the mobile phase to obtain an eluate fraction g; and (5) purifying the eluate fraction g by silica gel column chromatography using hexane/ethyl acetate gradient as the mobile phase to obtain a specific eluate fraction which could be purified further to obtain the anti-cancer active substance from Antrodia Camphorata.Type: ApplicationFiled: November 24, 2010Publication date: May 26, 2011Inventors: Been-Huang CHIANG, Yu-Wei LIN -
Patent number: 7947283Abstract: A method for treating psoriasis by providing a pharmaceutical composition containing at least Ganoderma lucidum extract and administering a therapeutically effective amount of the composition to a patient in need thereof. Also disclosed is a method for treating psoriasis by first purifying Ganoderma lucidum extract into at least one fraction, then providing a pharmaceutical composition comprising at least one of the Ganoderma lucidum fractions, and administering a therapeutically effective amount of the composition to a patient in need thereof. A method for alleviating symptoms of psoriasis is disclosed. The symptoms of psoriasis are alleviated by providing a pharmaceutical composition containing at least Ganoderma lucidum extract and administering an amount of the composition effective to increase at least one of an IL-10 and IL-1Ra expression, whereby the symptoms of psoriasis are ameliorated.Type: GrantFiled: August 29, 2008Date of Patent: May 24, 2011Assignees: Wyntek Corporation, Academia SinicaInventors: Tseng-Rong Tu, Chia-Feng Li, Sung-Hsieh Su, Chi-Huey Wong, Eugene Fan
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Publication number: 20110117180Abstract: Disclosed are microcapsules with shells that are not animal by-products and methods for preparing and using such microcapsules.Type: ApplicationFiled: January 9, 2008Publication date: May 19, 2011Applicant: Ocean Nutrition Canada LimitedInventors: Cuie Yan, Wei Zhang, Yulai Jin, Lesek Alexa Demont, Colin James Barrow
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Publication number: 20110117121Abstract: Methods and compositions for therapy of pain are provided. Compositions comprising therapeutically effective amounts of two or more of an extract of Ganoderma lucidum, an extract of Salvia miltiorrhiza and an extract of Scutellaria barbata and optionally a therapeutically effective amount of an extract of Hippophae rhamnoides are provided. Novel synergistic effects of the use of these compounds in combination therapy are disclosed. Compositions exhibit multiple functions that are useful for the treatment of pain and inflammation. Compositions of the invention inhibit the activity of COX-2 to a greater extent than COX-1. Compositions of the invention also inhibit the nuclear accumulation of NF-kappaB and thus inhibit the expression of a number of proinflammatory molecules including COX-2.Type: ApplicationFiled: October 26, 2007Publication date: May 19, 2011Inventors: James Dao, Jeff Dao, Leslie Wilson, William Gerwick, Emin Oroudjev
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Publication number: 20110117122Abstract: The present invention discloses a composition and method for effecting various cytokines and NF-?B by administering an effective amount of a phyto-percolate composition to an individual. In various exemplary embodiments, the composition is claimed to be useful for the effective treatment of inflammation, cancer, and/or various infections including HIV by regulation of various interleukins, such as IL-10 and IL-2, and of transcription factors including NF-?B.Type: ApplicationFiled: November 16, 2010Publication date: May 19, 2011Inventors: Tiffany Thomas, Fazlul Sarkar, Denis M. Callewaert, Andrew Dahl, Enrique Martinez
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Patent number: 7939081Abstract: The present invention provides a process for producing cercosporamide comprising culturing a fungus belonging to the genus Lachnum and/or fungus belonging to the genus Pseudaegerita and recovering cercosporamide from the culture thereof. In addition, the present invention provides cercosporamide acquired according to this production process. Further, the present invention provides novel microorganisms consisting of Lachnum fuscescens SANK 19096, Lachnum calycioides SANK 12497, Lachnum caesaliatum SANK 10906, and Pseudaegerita websteri SANK 11006.Type: GrantFiled: August 8, 2006Date of Patent: May 10, 2011Assignee: Daiichi Sankyo Company, LimitedInventors: Tsuyoshi Hosoya, Jun Ohsumi, Kiyoshi Hamano, Yasunori Ono, Masami Miura
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Patent number: 7938981Abstract: A composition for deicing or for the preparation of a heat transfer fluid is provided. The composition comprises a mixture of at least two carboxylic acid salts having a t/c ratio of 2 or lower, including a dicarboxylic salt and a monocarboxylic salt, said dicarboxylic salt being present in the mixture in an amount of at least 50 wt % of the weight of the mixture, on a dry basis. More particularly, said mixture is including a succinate and a formate, wherein the succinate is in an amount of at least 50 wt %, on a dry basis. Also provided is a method for deicing a surface or preventing the accumulation of ice, snow or a mixture thereof on a surface, comprising a step of applying on a surface covered by ice, snow or a mixture thereof, or susceptible of being covered by ice, snow or a mixture thereof, the above composition. The composition is also useful for the preparation of a heat transfer fluid coolant to be used in a heat transfer system comprising a heat transfer fluid provided with a cooling system.Type: GrantFiled: September 24, 2010Date of Patent: May 10, 2011Assignee: Bioamber S.A.S.Inventors: Dilum Dunuwila, Roger L. Bernier