Toxoplasma Patents (Class 424/273.1)
  • Cloning of gene encoding the GP28.5 protein of Toxoplasma gondii; peptide fragments of said protein and their applications
    Patent number: 6392014
    Abstract: The invention relates to cloning of the gene for the toxoplasma GP28.5 antigen. It also encompasses purified GP28.5 antigen preparations and antigenic polypeptides derived from said antigen, and their applications.
    Type: Grant
    Filed: June 5, 1998
    Date of Patent: May 21, 2002
    Inventors: Marie-France Cesbron, Corinne Mercier, André Capron, André Tartar, Pierrette Maes
  • Device for storage and mucosal delivery of biological or pharmaceutical materials to animals
    Patent number: 6387378
    Abstract: Disclosed herein is a device for storing and/or delivering an effective amount of biological or pharmaceutical material to an animal comprising a tube disposed to contain said biological or pharmaceutical material and sealed at its ends and adapted to provide an opening through which the biological or pharmaceutical material exits and is administered to an intended site of the animal.
    Type: Grant
    Filed: September 9, 1993
    Date of Patent: May 14, 2002
    Inventors: George P. Shibley, Karen K. Brown, Leszek J. Choromanski, Sharon A. Bryant
  • Mimotopic polypeptides of toxoplasma gondii and applications
    Patent number: 6372897
    Abstract: The invention relates to a polypeptide capable of reacting specifically with an anti-Toxoplasma gondii P30 protein antibody, and comprising a peptide sequence, in which any succession of 6 contiguous amino acids exhibits at most 67 % homology with the peptide sequence of said P30 protein, identified by SEQ ID No.1, or comprising a sequence derived from said peptide sequence, and the applications of this polypeptide especially for detecting a Toxoplasma gondii infection, in a biological sample.
    Type: Grant
    Filed: October 2, 1998
    Date of Patent: April 16, 2002
    Assignee: Bio Merieux
    Inventor: Jolivet-Reynaud Colette
  • Toxoplasma gondii antigens, the preparation thereof and the use thereof
    Patent number: 6326008
    Abstract: The present invention relates to the identification of toxoplasma gondii antigens and the preparation thereof by genetic engineering. A cDNA expression gene bank of this parasite was prepared. Recombinant clones which are of diagnostic interest were identified using a high-titer rabbit anti-Toxoplasma gondii serum, and isolated.
    Type: Grant
    Filed: December 16, 1999
    Date of Patent: December 4, 2001
    Assignee: Dade Behring Marburg GmbH
    Inventors: Stefan Knapp, Robert Ziegelmaier, Hans Küpper