Abstract: A pharmaceutical composition comprising at least 0.1 ?mol of formaurindicarboxylic acid or its derivatives in 1 kg of pharmaceutically acceptable carrier. The pharmaceutical composition of claim 1 wherein the composition is in the form of solution prepared using aqueous alcali or water.

Abstract: A topical, foamable composition is provided that includes at least one antifungal agent that is able to penetrate the upper layers of skin and is retained in or on an area to be treated for a prolonged period of time, and that has a residual non-volatile component content of less than 25%. In addition, a method of treating fungal diseases including jock itch, tinea, dandruff and sebborheic dermatitis is provided, and includes applying to the affected area of a patient requiring such treatment an antifungal composition.

Abstract: Water-in-oil emulsions, compositions, and methods that include a vinyl polymer that includes ethylene oxide-containing side chains and alkyl-Y-containing side chains, wherein Y is O or NR, wherein R is H or CH3, and wherein the alkyl group of the alkyl-Y-containing side chain has at least 4 carbon atoms on average in a cyclic, branched-, or straight-chain configuration and optionally including one or more heteroatoms.

Abstract: An antimicrobial fabric and method for treating fabric to impart antimicrobial properties thereto by preparing an aqueous solution of eugenol, polyvinyl alcohol, and glyoxal, padding the fabric with the aqueous solution to achieve a preselected desired part by weight wet pickup, drying the fabric; and curing the fabric.

Abstract: A two-part disinfecting systems, as well as disinfecting compositions and methods for making and using the same. The two-part disinfecting system contains a first part and a second part adapted to be mixed to yield an aqueous disinfecting composition, wherein the first part comprises a chlorite and the second part comprises an acid, and wherein the first part, the second part, or both the first and second parts comprise an olefin compound.

Abstract: A method for using a commercially-available silver-coated anti-microbial wound dressing (sold under the trademark Silverlon) as a protective guard to prevent direct touch-contact between the hand of an individual and a contact surface. The protective guard establishes a barrier to prevent the spread of germs and potentially disease-causing bacteria from the contact surface to the individual's hand. The protective guard can be carried in the individual's hand and simply moved against the contact surface. Alternatively, the protective guard an be attached to, bent around or folded over the contact surface to prevent direct touch-contact therewith.

Abstract: The present invention relates to a process for the treatment of a cellulosic molded body, wherein the molded body is contacted with an acid solution of a chitosan. The process according to the invention is characterized in that the chitosan has a deacetylation degree of at least 80%, a nitrogen content of at least 7 w %, preferably at least 7.5 w %, a weight average molecular weight Mw (D) of 10 kDa to 1000 kDa, preferably 10 kDa to 160 kDa, and a viscosity in 1 w % solution in 1 w % acetic acid at 25° C. of 1000 mPas or less, preferably 400 mPas or less, in particular preferably 200 mPas or less.

Abstract: A medical product is provided that is selected from at least one of, nasal cannulas, oxygen masks, wound dressings, bandages, band aids, catheters, endotrachial tubes, condoms, surgical and other gloves, sheaths for endoscopy probes, and medical products that physically touch the body. A coating is included with at least one of, a non-antibiotic, antimicrobial and/or antiviral substance that prevents further local, non-systemic, colonization of infections.

Abstract: A non-irritating antimicrobial multi-layer or multi-ply tissue product made by treating an inner layer or ply or an inner surface of an inner layer or ply with one or more antimicrobial agents and treating the one or more outer layers or plies or the outer surfaces of the layers or plies with one or more irritation-inhibiting agents, and methods of making and using the same. The antimicrobial agent will remain confined to the inner portion of the tissue product, thereby preventing irritation to the user, and the irritation-inhibiting composition treated layer(s) or ply(s) provides a pleasing, soothing, non-irritating tactile quality to the tissue product. The non-irritating antimicrobial multi-layer or multi-ply tissue product further comprises an absorption enhancing agent. In one embodiment, the irritation-inhibiting composition comprises an oil, in which case the tissue product will also entrap any absorbed contaminant, holding it in contact with the antimicrobial agent.

Abstract: An antimicrobial protection gear for use by a person, the an antimicrobial protection gear comprising a 1st outer layer of woven/non-woven material treated with anti-microbial agent; and a 2nd inner layer of woven/non-woven material treated with anti-microbial agent. When a person coughs, the saliva, droplets and other body fluids ejected by the person is captured into the 1st outer layer, bacteria, viruses and micro-organisms in the said saliva, droplets and other body fluids are sterilized by the anti-microbial in the 1st outer layer, said saliva, droplets and other body fluids then absorbed into the 2nd inner layer, and all the bacteria, viruses and micro-organisms sterilized and trapped inside the 2nd inner layer and removed by washing. A 3rd layer or more layers can be included in the clothing accessory.

Abstract: The invention relates to the use of at least one strain of lactic acid bacteria and/or bifidobacteria having hydrophobic surface properties, for the preparation of a composition intended for the prevention or the treatment of endotoxin mediated and/or associated disorders and human or pet food compositions prepared thereof.

Abstract: The present invention discloses a layer of fabrics having antibacterial/microbe-resistant properties that are designed for contacting with the human skin. The fabric layer can be disposed, directly or indirectly, onto a pillowcase, pillow, comforter, comforter cover, head support, bed cloth, sleeping bag, mattress, cushion, blanket, and garment.

Abstract: Plastic films, fibers and articles are provided long-term antimicrobial activity with a combination of certain phenolic and inorganic antimicrobial agents. The plastic films, fibers and articles with antimicrobial activity exhibit superior resistance to discoloration, may be processed at high temperature, and maintain physical properties upon weathering, especially upon exposure to ultraviolet radiation.

Abstract: Plastic films, fibers and articles are provided long-term antimicrobial activity with a combination of certain phenolic and inorganic antimicrobial agents. The plastic films, fibers and articles with antimicrobial activity exhibit superior resistance to discoloration, may be processed at high temperature, and maintain physical properties upon weathering, especially upon exposure to ultraviolet radiation.

Abstract: The invention concerns the use of a fiber modified with functions capable of interacting with microbial cell wall proteins for immobilizing micro-organisms in hygiene products. Those functions are particularly capable of interacting with anionic groups and amine groups, and are especially cationic groups and aldehydes, respectively. The fibers may be synthetic or cellulosic. Also hygiene products containing these fibers are described.

Abstract: An article and process provides a stable technology that reduces the microbial content by providing molecular iodine to the stabilized reagents when at least two reactants are activated by aqueous and/or alcohol materials.

Abstract: There is provided an anti-microbial composition comprising a cationic peptide and a glycineglycine endopeptidase. The composition has been found to be synergistic against bacteria, especially Gram positive bacteria such as Staphylococcus aureus MSSA or MRSA. In one embodiment the composition comprises ranalexin, dermaseptin, magainin or mixtures thereof together with lysostaphin. The composition is useful for treating surfaces, including a wound surface in a patient or surfaces of an object (e.g. surgical instrument) or room.

Abstract: Disclosed are oligo- or polysiloxanes, which are characterized by containing at least 3, for example 4-3000, Si atoms in the main chain, and wherein at least one thereof is contained in a moiety of the formula (I) whose open bond of the O atom is linked to another Si atom of the oligo- or polysiloxane main chain, and whose open bond of the Si atom is linked either to another O atom of the oligo- or polysiloxane main chain or to R?1, where R1 and R?1 independently are C1-C10alkyl, R2 and R3 independently are C1-C18alkylene, X is a divalent spacer group selected from O, NR4, N(COR?5), CONR?4, OCONR?4;.

Abstract: There is described a method for the deposition of silver nanoparticles on the surface of natural or synthetic textile fibers.

Abstract: Antifungal and antibacterial peptides, polypeptides and proteins as antifungal additives for paint and other coatings are disclosed, along with antifungal compositions, and coated surfaces with antifungal properties. Methods of using the coatings for treating and/or inhibiting growth of mold, mildew and other fungi and bacteria on objects such as building materials that are susceptible to such infestation are also disclosed.

Abstract: A medical device having an antimicrobial coating. The device has a first coating layer having an antimicrobial agent over at least part of the outer surfaces of the device. The first coating has an outer surface. There is a second discontinuous polymeric coating containing an antimicrobial agent, which is on top of and covering part of the outer surface of the first coating. The second discontinuous coating has a microstructure.

Abstract: Antifungal and antibacterial peptides, polypeptides and proteins as antifungal additives for paint and other coatings are disclosed, along with antifungal compositions, and coated surfaces with antifungal properties. Methods of using the coatings for treating and/or inhibiting growth of mold, mildew and other fungi and bacteria on objects such as building materials that are susceptible to such infestation are also disclosed.

Abstract: Fibrous antimicrobial materials for use in structures and barrier applications, such as face masks and wound dressings, have been developed from antimicrobial polymeric materials. The fibrous antimicrobial materials also are particularly suitable for use in air and water filtration. The antimicrobial polymeric materials are prepared from solid solutions of antimicrobial bisguanide compounds blended with certain thermoplastic polymers. The antimicrobial polymeric materials may be extruded into fibers or used in the particulate form for preparation of the nonwoven antimicrobial materials. The antimicrobial bisguanide compound, such as chlorhexidine, are distributed at the molecular level within at least one thermoplastic polymer, such as a polyolefin in which the antimicrobial bisguanide compound is soluble, to form a miscible blend. Methods for their formation and use also are provided.

Abstract: The present disclosure provides antimicrobial compositions for use in textiles, as well as methods of preparing these compositions and treating textiles with these compositions.

Abstract: An effective controlled release pest control composition can use activated carbon as the sole release agent. Liquid pesticide is adsorbed into the interior mesopore and macropore space of the activated carbon. Upon contact with water, the pesticide is slowly displaced from the carbon into the environment for appropriate control. The particulate can be used as is or can be combined with liquid or solid diluents. The particle can be formed into larger composites comprising a granule, a pellet, and an agglomerated particle, etc. A variety of pesticides can be used including insecticides, herbicides, fungicides, growth regulators, etc.

Abstract: A process for preventing a protozoal disease by the administration of an alkyl phosphocholine to a human being.

Abstract: A peptide including a first peptide sequence of formula KLAKLAK (SEQ ID NO:11)in which K is lysine, L is leucine and A is alanine, and a second peptide sequence of formula (B) in which B is a peptide of 4 to 15 amino acids positively charged at neutral pH, including at least one peptide motif of formula ?xx? (SEQ ID NO:13)in which ? is a basic amino acid and X is any amino acid, and in which the first peptide sequence is repeated n times and the second peptide sequence is repeated m times, n and m being whole numbers between 1 and 5.

Abstract: A composition for burn treatment containing, in % by weight: Almond oil (sweet): ?9-10 Almond oil (bitter): 7-8 Lavender oil: 4-5 Beeswax: 8-9 Bee Pollen: 3-4 Purified honey: 50-60 Propolis: 0.2-1?? Water: ??8-12.

Abstract: An article is applied to the body of an animal (including humans) to provide both absorbency and antimicrobial activity. The article may comprise a water absorbent material; and a composition that reacts with water to produce molecular iodine. The composition provides a local concentration (in the water) of at least 10 parts per million iodine in water carried by the material (that is actual water supported by the water absorbent material) when the material has 5% by weight of water present in the water absorbent. The article may be a diaper, sanitary pad, bandage, bandaid or wrap for an animal.

Abstract: The present invention relates to protecting a human from an infection using a disinfecting agent as described herein and a method for use thereof, more particularly to a rare earth-containing device for protecting a wound and a method for use thereof.

Abstract: A subject of the present invention is mutated hyperthermophilic phosphotriesterases (PTEs) possessing a lactonase activity, and their uses as bioscavengers within the context of the decontamination of the surfaces of materials, of the skin or mucous membranes, contaminated with organophosphorus compounds, or within the context of the preparation of medicaments which can be used within the context of the prevention or treatment of an external contamination or of an internal poisoning by ingestion or inhalation by organophosphorus compounds, or within the context of the pollution control of water polluted with organophosphorus compounds.

Abstract: Biostable, multipurpose, microbicidal intravaginal devices in the form of rings, ringed-meshes, sponges, or diaphragms for use by women and condoms for use by male partners are provided, wherein each of the devices contains a drug effective in treating a particular vaginal infection, while further exhibiting at least one additional function selected from the group dealing with non-hormonal contraception, management of sexually transmitted diseases, viral infections, and retroviral infections as well as the treatment of cervical cancer.

Abstract: A composition having effective broad spectrum preservation activity comprising a mixture of caprylyl glycol or one or more analogs thereof, or mixtures thereof with a preservative selected from the group consisting of: (1) chloroxylenol and 2-phenoxyethanol, (2) chloroxylenol and chlorphenesin, (3) chlorphenesin and 2-phenoxyethanol, and (4) chloroxylenol, chlorphenesin and 2-phenoxyethanol.

Abstract: Monodisperse macromolecular conjugate compositions of a peptidic carrier irreversibly or reversibly conjugated with one or more effectors and one or more therapeutic agents, wherein at least one effector or therapeutic agent is attached to a pendant reactive group on said peptidic carrier via a water-soluble polymer. Monodispersity is obtained through the use of orthogonal and separate conjugation reactions.

Abstract: The invention relates to the use of octenidine dihydrochloride for manufacturing a semisolid pharmaceutical composition for the treatment of wounds, atopic dermatitides, infected eczemas, dermatomycoses, vaginal infections, acne, herpes and/or for controlling multidrug-resistant pathogens, where the composition comprises from 0.005 to 5% by weight octenidine dihydrochloride, and a corresponding composition.

Abstract: Foaming alcohol compositions with selected dimethicone surfactants are disclosed. The dimethicone surfactants are PEG-8 to PEG-12 linear dimethicone surfactants and in particular PEG-10 linear dimethicone surfactant. The compositions are useful as antimicrobial products and in particular handcare or skincare products.

Abstract: An antimicrobial formulation containing a pyridine thiol and a bis-quinolinium salt which contains a cation of formula (I) below: wherein n is an integer from 3 to 18. The formulation may in particular be used for the treatment of a bacterial condition, more particularly acne or body odour. It is suitably applied topically.

Abstract: This invention relates to agricultural compositions, particularly pesticidal compositions which find particular use as a fungicide or herbicide composition. The pesticidal composition can include one or more fatty acids and one or more organic acids different from the fatty acid. The organic acid can but need not exhibit any fungicidal activity; however, when combined with a fatty acid, the organic acid functions as a potent synergist for the fatty acid as a fungicide. Additionally, the pesticidal composition can include other components such as emulsifiers, adjuvants, surfactants and diluents. The pesticidal composition significantly reduces or prevents the fungal infection of cash crops including vegetables, fruits, berries, seeds, grains and at higher application rates, can also be used as a herbicide and/or harvest aid or desiccant for harvested crops such as potatoes. The addition of an emulsifier further enhances the herbicidal properties of the compositions.

Abstract: The present invention discloses compositions derived from an isolated Bacillus species, spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain, suitable for topical application to the skin or mucosal membranes of a mammal, which are utilized to inhibit the growth of bacterium, yeast, fungi, virus, and combinations thereof. The present invention also discloses methods of treatment and therapeutic systems for inhibiting the growth of bacterium, yeast, fungi, virus, and combinations thereof, by topical application of therapeutic compositions which are comprised, in part, of isolated Bacillus species, spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain.

Abstract: It is believed that the abnormal absorption of endotoxin present in the gastrointestinal tract relates to the pathogenesis of autoimmune diseases such as rheumatoid arthritis. In an animal model for rheumatoid arthritis, it is observed that arthritis is improved by removing endotoxin. The present invention provides an endotoxin-adsorbent, which is capable of removing endotoxin in the gastrointestinal tract and can be administered to humans safely. By using a non-digestible and non-absorbable, and therefore, safe endotoxin-adsorbent, which has a high endotoxin-binding capacity for removing large amounts of endotoxin present in the gastrointestinal tract, it is possible to prevent and treat autoimmune diseases such as rheumatoid arthritis.

Abstract: Provided herein are powder-free elastomeric articles exhibiting good antimicrobial and anti-blocking properties. Also provided herein are methods for the manufacture of such articles substantially free from antimicrobial interfering materials, as well as packaging means for maintaining antimicrobial efficacy.

Abstract: The present invention relates to an antifungal protein gene and cDNA sequence thereof, which is obtained by mining the whole genome sequences of Monascus pilosus BCRC 38072 and the unigene database. The gene can encode an antifungal protein MAFP1. A purified protein obtained from M. pilosus culture broth having molecular weight of about 7 kDa is identified as MAFP1 by N-terminal protein sequencing and comparative analysis. The purified MAFP1 protein can inhibit the growth of pathogens such as Paecilomyces variotii BCRC 33174 and Helminthosporium panici BCRC 35004. In addition, it is found by PCR test that the gene of this antifungal protein exists in other Monascus species such as M. Barkeri, M. floridanus, M. lunisporas, M. pilosus, M. ruber and the like. It is also been proved that the mafp1 gene and cDNA thereof in four Monascus strains, M. pilosus (BCRC 38072, BCRC 38093 and BCRC 31502) and M. ruber BCRC 31533, have the same DNA sequences.

Abstract: The present invention relates to compositions and absorbent articles including compositions for protecting the skin barrier. The compositions can be applied to the bodyfacing surfaces of absorbent articles so that the compositions come into contact with the skin. The compositions of the invention provide several benefits including prevention and alleviation of skin irritations associated with the use of absorbent articles. The compositions can include hydrophilic and non-aqueous components as well as extracted botanical actives.

Abstract: The use of Titanium metal fine-particles for increasing of effect of the germicidal medicines used for human skin, skin infection and traumatism, is provided. The application of the Titanium metal fine-particles layer being laid on or close to skin, in combination with a medicine, functions to restrain bacteria breeding and multiplying, accelerate skin and dermic-organism metabolism, and promoting capillary purification. By these functions, an environment which is harmful and fatal for bacteria breeding/multiplying will be developed on the human body skin and dermic-organism. These functions are demonstrated by the increased effects of the germicidal medicines which are used for human skin dermatosis, skin infection and traumatism.

Abstract: A therapeutic, cosmetic or cosmeceutic composition for topical application, capable of stabilizing an active ingredient and delivering the active ingredient, comprising a plurality of microcapsules having a core-shell structure. The microcapsules have a diameter of approximately 0.1 to 100 micron. The core of each microcapsule includes at least one active ingredient and is encapsulated within a microcapsular shell. The shell is comprised of at least one inorganic polymer obtained by a sol-gel process, and the shell protects the active ingredient before topical application and is designed to release the active ingredient from the microcapsules following application. The composition is useful in encapsulating active ingredients, such as benzoyl peroxide, that are unstable in other formulation, or are irritating to the skin.

Abstract: An antimicrobial composition of 3-iodo-2-propynylbutyl carbamate (IPBC) and 1,3-butylene glycol (BG) as solvent, in a defined weight ratio, preferably 9-11% IPBC and 89-91% BG, and personal care formulations including the composition in an amount of about 0.1-0.2% therein, at a pH of 4-9, is described.

Abstract: This invention relates to agricultural compositions that find particular use as a fungicide composition. The fungicide composition can include one or more fatty acids and one or more organic acids different from the fatty acid. The organic acid can but need not exhibit any fungicidal activity; however, when combined with a fatty acid, the organic acid functions as a potent synergist for the fatty acid as a fungicide. Additionally, the fungicide composition can include other components such as emulsifiers, adjuvants, surfactants and diluents. The fungicide composition significantly reduces or prevents the fungal infection of cash crops including vegetables, fruits, berries, seeds, grains and at higher application rates, can also be used as a harvest aid or desiccant for harvested crops such as potatoes.

Abstract: The invention relates to a method for treating an at least partially metallised textile, according to which said textile is treated with at least one agent selected from the group consisting of reductants and complex formers. The invention also relates to a textile treated in this way and to the use thereof for the anti-microbial treatment of liquids or for producing hosiery, insoles, clothing, covers for seating furniture or mattresses. A textile that has been treated according to the invention is capable of an adjustable, purpose-specific metal delivery depending on the field of application.

Abstract: Plastics and coatings are provided outstanding antimicrobial activity by incorporation therein of elemental silver and silver supported on a zeolite or on a glass. The compositions are suitable for medical use, for example for tubes, catheters, textiles and the like. The plastic textiles are woven or nonwoven. The plastics are for example polyurethane, polycarbonate, liquid silicone rubber, polypropylene or polyethylene or polymer composites.

Abstract: A substrate treated with a lotion including a skin pH balancing compound and a base lotion. The pH balancing compound is preferably an organic acid, such as an alpha-hydroxy acid, an alpha-dihydroxy acid, or a beta-hydroxyacid, a combination of an organic acid and a salt of an organic acid, or a buffer combination, such as combinations of citric acid and disodium phosphate, or disodium citrate and sodium hydroxide. The preferred lotion has the effect of maintaining the skin acid mantle while making the treated substrate, preferably tissue, towel or napkin, optionally wet-strengthened, wipe or nonwoven material, feel smooth, lubricious and nongreasy. The skin care benefits of the lotionized substrate are expressed whether the product is used dry or prewetted with water.