Food Or Edible As Carrier For Pharmaceutical Patents (Class 424/439)
  • Patent number: 8865240
    Abstract: A palatable, edible soft chewable medication vehicle for delivery of a pharmaceutically acceptable active ingredient, such as a drug, to an animal or human subject. The edible soft chews contain only food grade or better inactive ingredients, and preferably do not contain ingredients of animal origin. Processes for manufacturing the edible soft chews do not require the use of heat or the addition of water during mixing of active and inactive ingredients, provide stable concentrations of the active ingredient, and produce chews of consistent weight and texture.
    Type: Grant
    Filed: August 14, 2013
    Date of Patent: October 21, 2014
    Assignee: Bayer Healthcare LLC
    Inventors: Neil E. Paulsen, Roland H. Johnson, Michael B. Coffee
  • Patent number: 8865203
    Abstract: Compositions and methods to improve the pharmacokinetic profile of S-Adenosylmethionine (SAMe) are provided, as are methods of treating various disorders using SAMe formulations with improved pharmacokinetic profiles. More specifically, the invention is directed to methods of treating a disease or disorder in a subject and/or improving the nutritional status of a subject by administering formulations exhibiting improved pharmacokinetic profiles of exogenous SAMe. The method also includes the step of orally administering compositions of the invention to the subject once per day after overnight fast; that is prior to food intake in the morning.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: October 21, 2014
    Assignee: Methylation Sciences International SRL
    Inventors: Nancy Harrison, I. David MacDonald, Aniko Takacs-Cox, Robert Miller
  • Patent number: 8859612
    Abstract: The invention relates to the use of the compound hesperidin or of one of its derivatives for the manufacture of a composition designed to stimulate bone formation and/or inhibit bone resorption in man or animals.
    Type: Grant
    Filed: June 27, 2003
    Date of Patent: October 14, 2014
    Assignee: Institut National de la Recherche Agronomique (INRA)
    Inventors: Marie-Noëlle Horcajada, Véronique Coxam, Christine Morand, Marie-Jeanne Davicco
  • Patent number: 8853192
    Abstract: A fat or oil composition containing the following ingredients (A) and (B): (A) 100 parts by weight of a fat or oil containing 15 wt. % or more of diacylglycerols having, in the constituent fatty acids thereof, an unsaturated fatty acid content of 80 wt. % or more, a conjugated linoleic acid content of from 2 to 92 wt. %, and an ?3 unsaturated fatty acid content of less than 15 wt. %; having a monoacylglycerol content of 5 wt. % or less and a free fatty acid content of 5 wt. % or less; and containing 1,3-diacylglycerol/1,2-diacylglycerol at a weight ratio of from 1 to 5; and (B) from 0.001 to 2 parts by weight of a tocopherol.
    Type: Grant
    Filed: August 11, 2006
    Date of Patent: October 7, 2014
    Assignee: Kao Corporation
    Inventors: Naoki Hosoya, Shin Koike, Takatoshi Murase
  • Publication number: 20140271782
    Abstract: A method for preparing ethanol-containing nanolipid particles, which can be used in food products, frozen desserts, or beverages. The method comprises nanolipidic vehicles in which ethanol-containing substances are encapsulated, said ethanol-containing nanolipidic vehicles can be combined with food products, desserts or beverage ingredients including those that are subsequently frozen, The food product, dessert or beverage can remain in a frozen state during consumption by an individual. A composition comprising ethanol-containing nanolipid particles, which can be used in food products, frozen desserts, or beverages.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Applicant: DERMAZONE SOLUTIONS, INC.
    Inventor: Michael W. Fountain
  • Patent number: 8828422
    Abstract: The present invention is directed to shelf-stable liquid egg material, methods for making the same, and method of using the same. The present invention is also directed to an animal feed supplement containing a stabilized IgY antibody titer in liquid eggs stored at room temperature for extended periods of time with the use of glycerol and preservatives. The stabilized liquid whole egg or stabilized liquid yolks of the egg containing non-specific or elevated specific IgY titer may be used as animal feed supplements animals to provide passive immunity to these animals. The stabilized nature of the IgY and liquid egg allows for extended shelf life of these liquid products at room temperature.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: September 9, 2014
    Assignee: R&D Lifesciences
    Inventors: Daniel J. DuBourdieu, Rajiv Lall
  • Patent number: 8828441
    Abstract: A spray-chilled particulate delivery system that has a crystalline matrix structure and includes a volatile hydrophobic active ingredient and a carrier material of erythritol, mannitol and mixtures thereof 75% or more of the carrier material, relative to the total weight of the carrier material, is in crystalline form. The system is prepared by a process that includes the steps of forming a melt of the carrier material, incorporating a volatile hydrophobic active ingredient into the melt, forming a melt-mixture comprising an emulsion, dispersion or suspension of the volatile hydrophobic active ingredient in the melt, forming discrete particles of the melt mixture, and cooling the discrete particles.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: September 9, 2014
    Assignee: Firmenich SA
    Inventors: Christopher Gregson, Matthew Sillick
  • Patent number: 8828472
    Abstract: The present invention relates to food products having a high omega-3 fatty acid content, as well as methods of preparing those food products.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: September 9, 2014
    Assignee: Ambo Innovations, LLC
    Inventor: Bo Martinsen
  • Patent number: 8821915
    Abstract: The present invention is directed to a method of treating a patient suffering from the metabolic syndrome and/or related disorders including obesity, Type 2 diabetes, pre-diabetes, hypertension, dyslipidemia, insulin resistance, endothelial dysfunction, pro-inflammatory state, and pro-coagulative state, and comprising the steps of (a) providing to the patient a dietary regimen that decreases overactive CNS noradrenergic tone; followed by (b) providing to the patient a dietary regimen that increases dopaminergic tone while maintaining the above decreased overactive CNS noradrenergic tone. The present invention is also directed to food products useful in implementing the dietary regimens.
    Type: Grant
    Filed: September 19, 2011
    Date of Patent: September 2, 2014
    Assignee: VeroScience, LLC
    Inventor: Anthony Cincotta
  • Patent number: 8815311
    Abstract: Embodiments of the invention generally relate to methods for improving thyroid function in healthy human beings.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: August 26, 2014
    Assignee: Quality IP Holdings, LLC
    Inventors: Amy L. Heaton, Mitchell K. Friedlander, Dennis Gay
  • Patent number: 8815279
    Abstract: A method is provided for reducing the extent of or occurrence of long-term adverse health effects in human infants, comprising feeding to said infants when newborn a nutrient-containing-formula providing not more than 1 gram of protein per 100 ml of formula and/or not more than 50 kcal per 100 ml of formula. Also disclosed are methods of administering the infant formulas to reduce the occurrence or extent of insulin resistance in an individual later in life, to reduce the occurrence or extent of obesity or atherosclerosis in an individual later in life, or combinations thereof, by feeding newborn infants the newborn infant formula described herein.
    Type: Grant
    Filed: January 6, 2009
    Date of Patent: August 26, 2014
    Assignee: University College London
    Inventors: Atul Singhal, Alan Lucas
  • Patent number: 8815280
    Abstract: The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
    Type: Grant
    Filed: December 9, 2009
    Date of Patent: August 26, 2014
    Assignee: Metabolic Technologies, Inc.
    Inventors: John Rathmacher, John Fuller, Jr., Shawn Baier, Steve Nissen, Naji Abumrad
  • Publication number: 20140234391
    Abstract: A method for reducing the population of pathogenic bacteria in an animal being reared in an animal rearing facility is provided. The method involves using one or more than one naturally-occurring location-specific bacteriophages selected to be highly specific to the strains of the one or more than one pathogen present in the facility, a phage component derived from the one or more than one naturally-occurring location-specific bacteriophages, or a combination thereof, to produce a location-specific bacteriophage preparation. The preparation is administered to the animal, to reduce the one or more than one pathogenic bacteria. The method may also involve a step of identifying location-specific isolates of the one or more than one pathogenic bacteria at or near the animal rearing facility.
    Type: Application
    Filed: June 29, 2012
    Publication date: August 21, 2014
    Inventor: Kishore Murthy
  • Patent number: 8808764
    Abstract: Embodiments of the invention generally relate to methods and supplements for improving the health of human beings.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: August 19, 2014
    Assignee: Quality IP Holdings, LLC
    Inventors: Amy L. Heaton, Mitchell K. Friedlander, Dennis Gay
  • Patent number: 8808763
    Abstract: Embodiments of the invention generally relate to methods and supplements for improving sleep efficiency in human beings.
    Type: Grant
    Filed: September 19, 2012
    Date of Patent: August 19, 2014
    Assignee: Quality IP Holdings, LLC
    Inventors: Amy L. Heaton, Mitchell K. Friedlander, Dennis Gay
  • Patent number: 8791076
    Abstract: The invention relates to compounds of Formula I: and pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, and R3 are defined as set forth in the specification. The compounds are agonists of neurotrophin (such as nerve growth factor) receptors.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: July 29, 2014
    Inventors: Pablo Villoslada, Angel Messeguer
  • Patent number: 8790687
    Abstract: The present invention relates to the triterpene compounds improving in brain functions. In particular, the present invention relates to a novel use of the triterpene compounds represented by the Formula 1 for improving decreased memory and a pharmaceutical composition for improving brain functions comprising the triterpene compounds represented by the Formula 1.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: July 29, 2014
    Assignee: SK Chemicals Co., Ltd.
    Inventors: Wonrack Choi, Chang-Kyun Han, Tae Kon Kim, Guang-Jin Im, Chil Mann Jung, Se Jun Yun, Bongcheol Kim, Soomin Lee, Wie-Jong Kwak
  • Patent number: 8784308
    Abstract: A system and method are provided for securing an ingestible electronic device to a pharmaceutical product without damaging the ingestible electronic device. The product includes the ingestible electronic device being placed on the product in accordance with one aspect of the present invention. In accordance with another aspect of the present invention, the ingestible electronic device is placed inside the product. Various embodiments are disclosed in accordance with the present invention for protecting and/or coating of the electronic marker as well as securing the ingestible electronic device onto the product.
    Type: Grant
    Filed: December 2, 2010
    Date of Patent: July 22, 2014
    Assignee: Proteus Digital Health, Inc.
    Inventors: Hooman Hafezi, Robert Duck, Timothy Robertson, Benedict Costello
  • Patent number: 8784792
    Abstract: A pharmaceutical composition comprising a polymeric binder including a high molecular weight synthetic polymer having a backbone constituted of non hydrolysable covalent bonds, said polymer being able to form electrostatic bonds at a pH lower than the isoelectric point of gluten and peptides derived from the degradation of gluten, and being able to bind to gluten or peptides derived from the degradation of gluten in the gastrointestinal tract, and a pharmaceutically acceptable carrier. Methods of using the polymeric binder for binding gluten or a peptide derived from the degradation of gluten, for decreasing the degradation of gluten into toxic peptides or for decreasing interaction of gluten or peptides derived from the degradation of gluten with the gastrointestinal mucosa.
    Type: Grant
    Filed: May 1, 2012
    Date of Patent: July 22, 2014
    Assignee: Valorization-Recherche Limited Partnership
    Inventors: Jean-Christophe Leroux, Mohamad Nasser Eddine
  • Patent number: 8778384
    Abstract: The invention relates to a composition comprising a pharmaceutically active agent and a bioadhesive delivery system that provides for the oral delivery of a vaccine to animals, particularly aquatic animals.
    Type: Grant
    Filed: May 8, 2012
    Date of Patent: July 15, 2014
    Assignee: Advanced Bionutrition Corporation
    Inventors: Moti Harel, Brian Carpenter
  • Patent number: 8772270
    Abstract: The invention provides methods for treatment of conditions which require phytosterol therapy without adversely affecting the bioavailability of lipophilic vitamins or lipophilic drugs. The method includes administering a mixture of phytosterol ester(s) (PS-E) and 1,3-diglyceride(s) (DAG) dissolved in an edible oil or fat. The invention also provides a method of improving weight management and a method of treating metabolic conditions that result in overweight. Dietary nutrients, food supplements and food articles containing the mixture are also provided.
    Type: Grant
    Filed: February 12, 2007
    Date of Patent: July 8, 2014
    Assignee: Enzymotec Ltd.
    Inventors: Avidor Shulman, Dori Pelled, Tzafra Cohen, Orly Farkash
  • Patent number: 8765195
    Abstract: Embodiments of the invention generally relate to methods and supplements for increasing sex steroids and human growth hormone in a human being.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: July 1, 2014
    Assignee: Quality IP Holdings, Inc.
    Inventors: Amy L. Heaton, Mitchell K. Friedlander, Dennis Gay
  • Publication number: 20140170203
    Abstract: A manufactured system for storage and delivery of an edible or potable substance is claimed.
    Type: Application
    Filed: December 10, 2013
    Publication date: June 19, 2014
    Inventors: David A. Edwards, Raphael Haumont, Francois Azambourg
  • Patent number: 8753684
    Abstract: The present invention relates to particulate UV protection agents which are obtainable by hydrothermal treatment of a particulate metal oxide and subsequent application of a manganese oxide coating, and to the preparation and use thereof. The present invention furthermore relates to novel compositions, in particular for topical application, which are intended, in particular, for light protection of the skin and/or hair against UV radiation and free-radical-induced stress, and to the use thereof in the above-mentioned cosmetic application.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: June 17, 2014
    Assignees: Merck Patent GmbH, Sachtleben Chemie GmbH
    Inventors: Frank Pfluecker, Bernd Hirthe
  • Patent number: 8748499
    Abstract: A stable dispersion of insoluble collagen is provided by a microfluidization process. The dispersions of insoluble collagen protein remain in stable suspension under long term storage conditions, with minimal or no settling or precipitation. More specifically the invention provides a stable dispersion of insoluble collagen comprising collagen particles wherein 50% by volume of said particles are less than 30 micrometers in width. These dispersions provide collagen in an aqueous form, which enables ease of incorporation into food and beverages and ease of administration to people or other mammals in need of collagen.
    Type: Grant
    Filed: April 9, 2010
    Date of Patent: June 10, 2014
    Assignee: Interhealth Nutraceuticals, Inc.
    Inventors: Francis C. Lau, Massood Moshrefi
  • Patent number: 8747921
    Abstract: Embodiments of the invention generally relate to methods and supplements for improving the health of human beings.
    Type: Grant
    Filed: September 19, 2012
    Date of Patent: June 10, 2014
    Assignee: Quality IP Holdings, Inc.
    Inventors: Amy L. Heaton, Mitchell K. Friedlander, Dennis Gay
  • Patent number: 8747922
    Abstract: Embodiments of the invention generally relate to methods and supplements for increasing sex steroids and human growth hormone in a human being.
    Type: Grant
    Filed: September 19, 2012
    Date of Patent: June 10, 2014
    Assignee: Quality IP Holdings, Inc.
    Inventors: Amy L. Heaton, Mitchell K. Friedlander, Dennis Gay
  • Patent number: 8747923
    Abstract: A method of improving health in a canine includes administering to the canine a nutritional supplement comprising an amino acid secretagogue composition, which stimulates the pituitary gland of the canines to produce growth hormone. The nutritional supplement may be administered orally. The nutritional supplement may comprise L-arginine hydrochloride, Oxo-proline, L-lysine hydrochloride, and cysteine. When desired, the nutritional supplement may consist essentially of L-arginine hydrochloride, Oxo-proline, L-lysine hydrochloride, N-acetyl-L-cysteine, L-glutamine, and schizonepeta powder.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: June 10, 2014
    Assignee: Quality IP Holdings, Inc.
    Inventors: Amy L. Heaton, Mitchell K. Friedlander, Dennis Gay
  • Patent number: 8747939
    Abstract: The present invention relates to a nutrient composition which contains at least a carbohydrate, a lipid, a protein, and a mineral, and is liquid or semisolid, characterized in that the volume-based median size (d50) of particles in the nutrient composition is 5 to 100 ?m and water-insoluble particles having a protein insolubilized by a divalent cation are contained as a major component of the nutrient composition, or a nutrient composition which contains at least a carbohydrate, a lipid, a protein, and a mineral, and is liquid or semisolid, characterized in that water-insoluble particles having a protein insolubilized by a divalent cation are contained as a major component of the nutrient composition and the mass of the protein with respect to the total moles of divalent ions forming the water-insoluble particles is 1.5 to 3 g/mmol.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: June 10, 2014
    Assignee: Ajinomoto Co., Inc.
    Inventors: Itaru Kon, Naoki Hayashi, Tatsuro Tanaka, Hisayuki Uneyama, Shinji Somekawa
  • Patent number: 8733368
    Abstract: A device which facilitates the absorption of nicotine in order to reduce the incidence of tobacco smoking is disclosed. The device includes a tube defining an interior space. The tube has a first end with an opening and a second end. An inhalable, flowable liquid or gel composition is disposed in the interior space of the tube. The composition may include water, at least one vitamin, a flavoring agent, and nicotine. The flavoring agent may include an intense sweetener such as sucralose, and a natural or artificial fruit flavor. A user inhales on the first end of the tube of the device as a substitute oral activity to tobacco smoking and thereby ingests a source of nicotine that reduces the withdrawal symptoms experienced when smoking is stopped.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: May 27, 2014
    Assignee: Smoke-Break, Inc.
    Inventors: Brett J. Roth, Terrill S. Clayton
  • Patent number: 8734864
    Abstract: Embodiments of the invention generally relate to methods and supplements for increasing human growth hormone (hGH) levels in healthy human beings.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: May 27, 2014
    Assignee: Quality IP Holdings, Inc.
    Inventors: Amy L. Heaton, Mitchell K. Friedlander, Dennis Gay
  • Patent number: 8734807
    Abstract: Schistosomiasis mansoni is caused by flukes called Schistosoma(es) that enters the human body through the skin in Schistosoma infested waters. The Schistosomes travel from the skin into human blood vessels where they mate, produce antigen containing eggs that travel from the blood vessels into the small intestines, where they are released in the human feces. Male and female Schistosome mates in human blood vessels, male Schistosomes secrete a protein called TGR ? protein to the Trk receptor sites on the females Schistosomes membranes. The process stimulates the formation of chemical SmInAct in female Schistosomes, a chemical necessary for the female Schistosomes to produce eggs. This novel technique describes new methods to inhibit Trk receptor sites on female Schistosome membranes using Trk inhibitor agent to prevent TGR ? proteins from binding to the Trk receptor sites. Thus, preventing SmInAct from being created in female Schistosomes, preventing production of eggs and Schistosomiasis.
    Type: Grant
    Filed: April 6, 2013
    Date of Patent: May 27, 2014
    Inventor: Gabriel Langlois-Rahme
  • Patent number: 8722114
    Abstract: Embodiments of the invention generally relate to methods and supplements for increasing human growth hormone (hGH) levels in healthy human beings.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: May 13, 2014
    Assignee: Quality IP Holdings, LLC
    Inventors: Amy L. Heaton, Mitchell K. Friedlander, Dennis Gay
  • Patent number: 8721540
    Abstract: The present invention provides for safe and reliable electronic circuitry that can be employed in ingestible compositions. The ingestible circuitry of the invention includes a solid support; a conductive element; and an electronic component. Each of the support, conductive element and electronic component are fabricated from an ingestible material. The ingestible circuitry finds use in a variety of different applications, including as components of ingestible identifiers, such as may be found in ingestible event markers, e.g., pharma-informatics enabled pharmaceutical compositions.
    Type: Grant
    Filed: November 18, 2010
    Date of Patent: May 13, 2014
    Assignee: Proteus Digital Health, Inc.
    Inventors: Hooman Hafezi, Eric J. Snyder, Benedict Costello
  • Patent number: 8722127
    Abstract: Bakery products and pasta with added chitosan are disclosed. The chitosan is addified with a biologically acceptable acid and added to pasta and baked products. Once the baked products and/or pasta are ingested, gastro-intestinal absorption of fats is limited even after cooking.
    Type: Grant
    Filed: February 2, 2006
    Date of Patent: May 13, 2014
    Assignee: Cor. Con. International S.R.L.
    Inventor: Umberto Cornelli
  • Patent number: 8722115
    Abstract: A method of improving health in an animal includes administering to the animal a nutritional supplement comprising an amino acid secretagogue composition, which stimulates the pituitary gland in the animal to produce growth hormone. The nutritional supplement may be administered orally. The nutritional supplement may comprise L-arginine hydrochloride, L-pyroglutamic acid, L-lysine hydrochloride, and cysteine. When desired, the nutritional supplement may consist essentially of L-arginine hydrochloride, L-pyroglutamic acid, L-lysine hydrochloride, N-acetyl-L-cysteine, L-glutamine, and schizonepeta powder.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: May 13, 2014
    Assignee: Quality IP Holdings, LLC
    Inventors: Amy L. Heaton, Mitchell K. Friedlander, Dennis Gay
  • Patent number: 8722066
    Abstract: The present invention provides, compositions, devices, and methods for affecting, among other things, weight loss and/or weight control, by sequestering nutrients or other compounds such as toxins from absorption in the digestive tract. The compositions, devices, and methods employ one or more members made of a compressible, absorbent matrix material. In various embodiments, the matrix material is suitable for routine use. The compressible absorbent matrix material has a size, shape and/or geometry configured for efficient packing into a small space, and/or configured to absorb and substantially retain digested material in the stomach. The devices and compositions may further comprise one or more hydrogel(s), soluble or insoluble fibers, waxes and/or gums to provide the desired mechanical properties and/or absorptive or shielding properties.
    Type: Grant
    Filed: March 27, 2012
    Date of Patent: May 13, 2014
    Assignee: Primigenia, LLC
    Inventor: Paolo Costa
  • Patent number: 8715752
    Abstract: Embodiments of the invention generally relate to supplements for increasing human growth hormone (hGH) levels in healthy human beings.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: May 6, 2014
    Assignee: Quality IP Holdings, Inc.
    Inventors: Amy L Heaton, Mitchell K Friedlander, Dennis Gay
  • Publication number: 20140120150
    Abstract: A consumable film adapted to adhere and to dissolve in the oral cavity that provides a local anesthetic and therapeutic agents for the treatment of oral burns or injuries. The film is designed to instantly release benzocaine, or other types of local anesthetic or therapeutic agent, upon adhesion to the affected areas of the mouth, and will continue to release sufficient quantities for pain relief and for healing over an extended period of time.
    Type: Application
    Filed: January 2, 2013
    Publication date: May 1, 2014
    Inventors: Robert W. McDonald, III, Kurt Fraivillig, Adriane Schiano, Elizabeth Vansant, Lance Hansen
  • Publication number: 20140112971
    Abstract: The present invention describes an orally administered edible product designed to provide a health benefit in a delivery formulation that will increase ease of use and thus lead to increased compliance and consumption to promote human health and wellness. The present invention provides an enhanced oral delivery method by developing edible products that can be ingested like food, are designed to taste like food not medicine, provide optimal absorption of lipophilic ingredients and allow for the delivery of the equivalent of multiple capsules in a single oral “dose” thus providing a superior method for the consumption of plant-based products.
    Type: Application
    Filed: October 22, 2012
    Publication date: April 24, 2014
    Inventors: Amita Shukla, Mukta Shukla
  • Patent number: 8703172
    Abstract: The present invention relates to a method for improving the composition of the intestinal flora, to a food comprising a sphingolipid for use in such a method, to methods for the preparation of such a food and to the use of sphingolipids for the preparation of a medicine for improving the composition of the intestinal flora. More in particular, the present invention relates to a method and food in which a sphingolipid chosen from the group consisting of phytosphingosine, sphingosine, lysosphingomyelin and sphinganine, or a precursor, a derivative, or suitable salt thereof is used.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: April 22, 2014
    Assignee: Nederlandse Organizatie voor Toegepastnatuurwetenschappelijk Onderzoek TNO
    Inventor: Willem Ferdinand Nieuwenhuizen
  • Patent number: 8703719
    Abstract: A method for regulating glucose release, promoting glycogen conservation, and/or glycogen synthesis includes orally administering an effective amount of a nutritional composition comprising fast and slow absorbing carbohydrates in combination with an insulinomimetic compound to provide a steady release of glucose from the gastrointestinal tract.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: April 22, 2014
    Assignee: Bio-Engineered Supplements and Nutrition, Inc.
    Inventors: Sal Abraham, Chris Ferguson
  • Patent number: 8703818
    Abstract: One embodiment described herein is related to methods and compositions, such as nutraceutical formulations and dietary supplements, comprising C16:1n7-palmitoleate or derivatives thereof. The methods and compositions comprising C16:1n7-palmitoleate, or derivatives thereof, safely and effectively prevent or mitigate manifestations of cardiovascular disease, including coronary artery disease and the accumulation of cholesterol or lipid deposits in the blood vessels of a subject.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: April 22, 2014
    Assignee: Tersus Pharmaceuticals, LLC
    Inventor: Jeffrey Green
  • Patent number: 8703173
    Abstract: Disclosed are newborn infant formulas comprising fat, carbohydrate, and from 0.5 to 2.5 g of protein per 100 ml of formula, wherein the formula has a caloric density of from 25 to 50 kcal per 100 ml of formula. Also disclosed are methods of administering the infant formulas to provide newborns with optimal nutrition, to reduce the occurrence or extent of insulin resistance in an individual later in life, to reduce the occurrence or extent of atherosclerosis or coronary artery disease in an individual later in life, or combinations thereof, by feeding newborn infants the newborn infant formula described herein.
    Type: Grant
    Filed: July 5, 2011
    Date of Patent: April 22, 2014
    Assignee: University College London
    Inventors: Atul Singhal, Alan Lucas
  • Publication number: 20140105958
    Abstract: An edible sticker including an edible paper, an edible ink, and an edible compound on at least a portion of the edible paper. The edible compound includes one selected from a nutrient, a supplement, a medicine, a mineral, a flavoring, a vitamin, and combinations thereof. A method of providing nutrients to a child using the edible sticker, a method of manufacturing the edible sticker, and a system for manufacturing the edible sticker have also been disclosed.
    Type: Application
    Filed: October 15, 2013
    Publication date: April 17, 2014
    Inventor: Bob D. NTOYA
  • Patent number: 8697145
    Abstract: There is provided a method for altering the distribution of body mass by altering the distribution of body mass by decreasing overall percentage fat and/or increasing the proportion of lean mass to fat mass comprising administering to a subject one or more compounds having the ability to alter body mass composition and/or ACE inhibiting activity or a physiologically acceptable derivative or prodrug thereof.
    Type: Grant
    Filed: July 26, 2011
    Date of Patent: April 15, 2014
    Assignee: Horizon Science Pty. Ltd.
    Inventors: David Kannar, Barry James Kitchen, Richard Stuart Weisinger
  • Patent number: 8697115
    Abstract: The present invention relates generally to a method of improving the antioxidant status of an infant. More particularly, the present invention relates to a method of improving the antioxidant status of an infant by administering a mixture of natural tocopherols. The natural tocopherol mixture is an effective blend of ?- and ?-tocopherol. For ease of administration and improved taste, the mixture of natural tocopherols are typically delivered in vehicle which may be in the form, for example, of a tablet, capsule, liquid, and nutritional formula. The present invention also relates to a method of improving the antioxidant status of an infant by supplementing the lactating woman wherein the supplemented breast milk is fed to the infant. Additionally, the present invention relates to a method of improving the antioxidant status of a newborn infant by supplementing the pregnant woman.
    Type: Grant
    Filed: March 29, 2006
    Date of Patent: April 15, 2014
    Assignee: Abbott Laboratories
    Inventors: Bridget Barrett-Reis, Marc L. Masor
  • Publication number: 20140093554
    Abstract: The present invention relates to a nutritional composition for infants and/or toddlers comprising a lipid component which has a large lipid globule size. The composition can be used to increase bone mineral content and/or bone mass density.
    Type: Application
    Filed: June 10, 2013
    Publication date: April 3, 2014
    Inventors: Eline Marleen VAN DER BEEK, Gelske SPEELMANS, Antonie VAN BAALEN, Annemarie OOSTING, Günther BOEHM
  • Patent number: 8685436
    Abstract: The invention relates to hydroxyflavanones, their salts and stereoisomers and their mixtures for suppressing or reducing the bitter and/or metallic taste impression. In addition, the invention relates to nutritional, nutritive or consumable preparations or oral pharmaceutical compositions, characterized in that these have an active content of hydroxyflavanones, their salts and stereoisomers or their mixtures.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: April 1, 2014
    Assignee: Symrise AG
    Inventors: Jakob Peter Ley, Gerhard Krammer, Günter Kindel, Ian-Lucas Gatfield, Manfred Müller
  • Patent number: RE45073
    Abstract: Disclosed is a powdered composition including an emulsifier and at least one anti-caking additive selected from the group consisting of earth alkali oxides, earth alkali hydroxides or a mixture thereof. Further disclosed is a method for preventing caking of a powdered composition comprising emulsifiers.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: August 12, 2014
    Assignee: Puratos Naamloze Vennootschap
    Inventors: Francois Heroufosse, Emmanuel Vanzeveren