Food Or Edible As Carrier For Pharmaceutical Patents (Class 424/439)
  • Patent number: 8685437
    Abstract: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film.
    Type: Grant
    Filed: March 26, 2009
    Date of Patent: April 1, 2014
    Assignee: MonoSol Rx, LLC
    Inventors: Robert K. Yang, Richard C. Fuisz, Garry L. Myers, Joseph M. Fuisz
  • Patent number: 8679522
    Abstract: A chewing gum with a liquid-fill composition and a surrounding gum region, with one or both containing active ingredients, such as herbal, medicinal and/or mineral elements or combinations thereof, present in an amount of at least about 0.05 mg.
    Type: Grant
    Filed: March 20, 2008
    Date of Patent: March 25, 2014
    Inventor: Jack Barreca
  • Patent number: 8673343
    Abstract: A method of orally administering jojoba for fat reduction, blood lipid reduction, and cancer prevention and treatment in humans is disclosed. The method incorporates a sufficient quantity of jojoba, defatted jojoba meal, jojoba extract, defatted jojoba meal extract, naturally derived or synthesized simmondsin, or any naturally derived or synthesized simmondsin derivative or analogue, including aglycon, or any mixture thereof into an individual's diet in the form of a food, dietary supplement, or drug to provide simmondsin component in an amount greater than 0.01% of one's total daily diet by weight, or 0.05 gram/day. The dosage amount and duration of the administration can vary to achieve and maintain one's desired body composition and blood lipid levels. The dosage and duration of administration are increased for cancer prevention and treatment.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: March 18, 2014
    Assignee: Yiwu Jiangr Bio-Technology HK Corp.
    Inventors: Yibing Wang, Peter J. Reilly, Yihong Wang
  • Patent number: 8668921
    Abstract: The present invention provides lipase inhibitors containing dimers of flavan-3-ols derived from teas as well as foods and beverages and medicines containing said inhibitors. More specifically, the present invention provides lipase inhibitors containing at least one of assamicains represented by the formula: wherein G represents a galloyl group; theasinensins represented by the formula: wherein R1 represents G or H, and R2 represents G; and theaflavins represented by the formula: wherein R1 and R2 independently represent G or H; as well as foods and beverages and medicines containing said lipase inhibitors.
    Type: Grant
    Filed: July 5, 2005
    Date of Patent: March 11, 2014
    Assignee: Suntory Holdings Limited
    Inventors: Masaaki Nakai, Yuko Fukui, Sumio Asami, Fumio Hashimoto
  • Patent number: 8668898
    Abstract: Methods and compositions for effectively lowering the carbon-14 content, particularly of DNA and histones in vertebrates, especially humans, to significantly below normal background levels and thereby reduce chromosomal damage using nutritional or dietary supplements based on low radiocarbon DNA, amino acid and histone precursors, further preferably including those which contribute the largest share of histone carbon atoms. Administration of the supplements during the earliest and/or most active growth stages of life is particularly beneficial. Particularly useful supplements are prepared by combining low radiocarbon precursor compounds with ordinary supplement or dietary components that exhibit substantially normal background radiocarbon concentrations.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: March 11, 2014
    Assignee: Radiocarb Genetics, Inc.
    Inventor: Christopher P. Williams
  • Patent number: 8662087
    Abstract: A device which facilitates the absorption of nicotine in order to reduce the incidence of tobacco smoking is disclosed. The device includes a tube defining an interior space. The tube has a first end with an opening and a second end. An inhalable, flowable liquid or gel composition is disposed in the interior space of the tube. The composition may include water, at least one vitamin, a flavoring agent, and nicotine. The flavoring agent may include an intense sweetener such as sucralose, and a natural or artificial fruit flavor. A user inhales on the first end of the tube of the device as a substitute oral activity to tobacco smoking and thereby ingests a source of nicotine that reduces the withdrawal symptoms experienced when smoking is stopped.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: March 4, 2014
    Assignee: Smoke-Break, Inc.
    Inventors: Brett J. Roth, Terrill S. Clayton
  • Patent number: 8663679
    Abstract: Disclosed are compositions and corresponding methods for treating fibrocystic breast disease or other breast-related disease or condition. The compositions comprise, per serving or dose, from zero to about 400 ?g selenium, from about 100 mg to about 6000 mg gamma linolenic acid, and about 0.15 mg to about 5 mg iodine, with nutritional embodiments further comprising one or more of protein, fat, carbohydrate, vitamins, and minerals and providing from about 50 to about 1000 kcal of energy per severing or dose. Also disclosed are in-vitro studies showing that certain combinations of gamma linolenic acid, iodine, and/or selenium may 1) inhibit breast cancer or fibrocystic cell proliferation, 2) reinforce the function of tight junctions of endothelial cells and of mammary epithelial cells in estrogen-sensitive conditions, and 3) reduce the risk of vascular invasion by breast cancer cells.
    Type: Grant
    Filed: April 28, 2005
    Date of Patent: March 4, 2014
    Assignee: Abbott Laboratories
    Inventors: Keith E. Rushlow, Robert A. Shalwitz, Terrence B. Mazer, Normanella T. Dewille, Tapas Das, Anand Seth
  • Patent number: 8658200
    Abstract: A chewing gum comprising at least one active pharmaceutical ingredient (API) with a core onto which is applied at least one inner polymer film coating and thereafter onto which is applied at least one outer hard coating. A preferred API is nicotine. Flavoring agents may be incorporated in the core, in the at least one inner polymer film coating and/or in the at least one outer hard coating. The gums formed exhibit a long lasting effect of flavoring agent(s) and result in the domination of flavoring agents in the coating(s) over flavoring agent(s) in the core, thereby (a) avoiding problems of chemical or pharmaceutical incompatibility between an API in the core and flavoring agent(s) in the coating(s) and (b) achieving an increased control of the release of the API and of non-active excipients.
    Type: Grant
    Filed: October 28, 2012
    Date of Patent: February 25, 2014
    Assignee: McNeil-PPC, Inc.
    Inventors: Seema Mody, Gregory Koll
  • Patent number: 8652563
    Abstract: The present invention relates to a nutrient composition which contains at least a carbohydrate, a lipid, a protein, and a mineral, and is liquid or semisolid, characterized in that the volume-based median size (d50) of particles in the nutrient composition is 5 to 100 ?m and water-insoluble particles having a protein insolubilized by a divalent cation are contained as a major component of the nutrient composition, or a nutrient composition which contains at least a carbohydrate, a lipid, a protein, and a mineral, and is liquid or semisolid, characterized in that water-insoluble particles having a protein insolubilized by a divalent cation are contained as a major component of the nutrient composition and the mass of the protein with respect to the total moles of divalent ions forming the water-insoluble particles is 1.5 to 3 g/mmol.
    Type: Grant
    Filed: February 27, 2008
    Date of Patent: February 18, 2014
    Assignee: Ajinomoto Co., Inc.
    Inventors: Itaru Kon, Naoki Hayashi, Tatsuro Tanaka, Hisayuki Uneyama, Shinji Somekawa
  • Patent number: 8652508
    Abstract: Dietary formulations in the form of an oil emulsion providing total enteral or parenteral nutrition, or in the form of food oil suitable for oral administration is provided. The formulations include about 2-60% by calories of a C20 or longer omega-3 fatty acid and about 0.05% to 1% by calories of arachidonic acid, where the formulation provides less than 1% of total calories from linoleic acid and alpha-linolenic acid, and where the fatty acids provide 5-60% of the total calories of said dietary formulation. Methods for treatment of diseases and disorders using the dietary formulations are also provided.
    Type: Grant
    Filed: May 27, 2008
    Date of Patent: February 18, 2014
    Assignees: Children's Medical Center Corporation, Beth Israel Deaconess Medical Center, Inc.
    Inventors: Mark Puder, Bruce Bistrian
  • Patent number: 8647674
    Abstract: This invention is concerned with the use of date syrup used as a binder (agglutinant) for solid dosage forms, such as tablets. The features of the granules and the tablets have been studied in comparison with granules and tablets which use different types of agglutinants such as starch paste and sucrose syrup and the results have shown that the use of date syrup as a binder for tablets yields results superior to other kinds of binders. In addition, date syrups gives the granules and tablets a fair color, good taste, distinct and pleasant odor, and it is favorable in regards to shape and taste by patients.
    Type: Grant
    Filed: March 25, 2010
    Date of Patent: February 11, 2014
    Assignee: King Saud University
    Inventors: Fars Kaed M. Alanazi, Ibrahim Abdullah Ibrahim Alsarra, Diaa Eldin Zidan Zidan Shaaban
  • Patent number: 8647687
    Abstract: Described is the use of isoamyl acetate in food compositions for weight management and/or weight control. Further described is a beverage containing isoamyl acetate.
    Type: Grant
    Filed: July 9, 2009
    Date of Patent: February 11, 2014
    Assignee: Nestec S.A.
    Inventors: Julie Laure Hudry, Johannes Le Coutre, Alexander Erin
  • Patent number: 8642051
    Abstract: Liquid activated infusion packet(s)/system, promoting hydration, containing active and/or inactive ingredients and/or a support member(s). Infusion Packet(s)/System is one or more individual compartments, and/or group(s), whereby the enveloping material(s) may be totally or partially dissolvable, edible, transparent, opaque, decorated, etc. Further, including of one or more: color(s), flavor(s), aroma(s), pharmaceutical(s), nutraceutical(s), dietary supplement(s), enzyme(s), pre/pro-biotic(s), amino-acid(s), soluble-fiber(s), diagnostic agent(s) etc. regardless of form, +/?effervescence, +/?uniform/controlled-release encapsulations into liquid for humans and/or animals. Enveloping material may be in whole and/or in combination; non-synthetic/porous, and/or synthetic porous/non-porous with deliberate perforations. Infusion Packet(s)/System+/?tag, support member for assistance, consumer compliance: promotion, advertising: education, entertainment, (toy/game), etc.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: February 4, 2014
    Inventor: Suzanne Jaffe Stillman
  • Publication number: 20140023693
    Abstract: A simple cellulose sulphate based microencapsulation technology has been applied to encapsulate bacterial or other microbial cells, which produce and release digestive enzymes and thereby provides an acid resistant shelter for these microbial cells. Surprisingly, the resulting spheres were found to provide sufficient protection for encapsulated cells from treatment with aqueous acidic solutions. Thereby the cellulose sulphate microencapsulated cells, such as probiotics are now enabled to survive passage, for example, through the stomach after consumption by a human or animal with a higher survival rate than those not within a microcapsule. After passing the stomach these cells are delivering products produced by them, e.g. enzymes or other nutrition factors. This technology therefore proves to be very useful in providing digestive or otherwise beneficial enzymes and/or of living microbial cells, into the lower gastrointestinal tract, where they could confer their health benefit to the host.
    Type: Application
    Filed: January 25, 2012
    Publication date: January 23, 2014
    Applicant: Austrianova Singapore Pte Ltd.
    Inventors: Walter H. Guenzburg, Eva Maria Brandtner, Brian Salmons Salmons, John A. Dangerfield
  • Publication number: 20140017293
    Abstract: Methods and compositions are provided for increasing the anaerobic working capacity of muscle and other tissues. Also provided are compositions formulated for the sustained release of free beta-alanine. Also provided is a dietary supplement formulated, for example, as a solid food product, an edible suspension, liquid or semi-liquid as described herein.
    Type: Application
    Filed: June 27, 2013
    Publication date: January 16, 2014
    Inventors: Roger Harris, John Wise
  • Publication number: 20140010859
    Abstract: The invention is directed to microcapsules, pharmaceutical or nutraceutical compositions comprising same, and methods for preparing and using same for delivery of nanoparticle coated emulsions comprising biologically active ingredients. The microcapsule comprises barley protein, oil, and a biologically active ingredient. The microcapsule is degradable to generate a nanoparticle comprising an oil droplet coated with a barley protein.
    Type: Application
    Filed: December 12, 2011
    Publication date: January 9, 2014
    Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventor: Lingyun Chen
  • Patent number: 8623442
    Abstract: The present subject matter relates to palatable beverages and compositions such as non-chocolate flavored water soluble dry powder compositions comprising a cocoa extract which comprises cocoa polyphenols, and an edible acid. The present subject matter further relates to processes for formulating said beverages and compositions.
    Type: Grant
    Filed: March 4, 2011
    Date of Patent: January 7, 2014
    Assignee: Mars, Incorporated.
    Inventors: Cesar Vega, Carol Lloyd
  • Patent number: 8617544
    Abstract: The present invention provides a neutraceutical formulation having unexpected optimizing effects on the release of various gastric hormones and which acts unexpectedly and synergistically to inhibit various metabolic reactions such as oxidation and glycation of lipoproteins, especially LDLs. An enhancement in the release of gastric hormones optimizes the release of various gastric juices, gastric enzymes, and endocrine secretion levels of hormones that have key roles in the metabolism, digestion, assimilation of caloric and non-caloric nutrients, the storage of body fats, and appetite satiety. The present composition has further effects as an antioxidant formulation and as an enhancer and stabilizer of the activity of other antioxidants.
    Type: Grant
    Filed: May 12, 2009
    Date of Patent: December 31, 2013
    Inventor: Richard L. Kozlenko
  • Patent number: 8618078
    Abstract: A method for controlling intestinal function, blood sugar level, body fat or serum lipid, or maintaining and improving glucose tolerance. The method comprises giving to human body or animal foods and drinks, having health benefits, or enriched with health benefits, wherein the foods and drinks comprise as an active ingredient a hydrogenated, indigestible dextrin that is obtained by digesting pyrodextrin with an enzyme to obtain an indigestible dextrin, and then hydrogenating the indigestible dextrin.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: December 31, 2013
    Assignee: Matsutani Chemical Industry Co., Ltd.
    Inventors: Yuka Kishimoto, Hiroshi Oga, Noriko Kitamura
  • Patent number: 8598191
    Abstract: The present invention is directed to oral pulse-release pharmaceutical dosage form containing an immediate release component of gamma-hydroxybutyric acid, and one or more delayed/controlled release components of gamma-hydroxybutyric acid.
    Type: Grant
    Filed: May 21, 2012
    Date of Patent: December 3, 2013
    Assignee: Supernus Pharmaceuticals, Inc.
    Inventors: Likan Liang, Niraj Shah, Padmanabh P. Bhatt, Scott Ibrahim
  • Patent number: 8597677
    Abstract: Compositions are provided comprising a balance between lysine and essential amino acids and metabolizable energy. The compositions are useful in methods to prevent or treat obesity in an animal without concomitant loss of lean muscle mass. The compositions may also be used in methods to preserve or to cause a gain in lean muscle mass in an animal in need thereof.
    Type: Grant
    Filed: February 23, 2007
    Date of Patent: December 3, 2013
    Assignee: Hill's Pet Nutrition, Inc.
    Inventors: Ryan Michael Yamka, Kim Gene Friesen
  • Patent number: 8591884
    Abstract: Methods and compositions are provided for increasing responsiveness to therapeutic metalloproteases including increasing and/or maximizing responsiveness and preventing botulinum and tetanus toxin resistance due to a functional deficiency of zinc. Also provided are methods for zinc replacement or supplement in lacking individuals comprising the administration of a zinc supplement for a loading period and/or administration of a phytase supplement together with the zinc supplement. Also provided are methods for standardization of botulinum toxin potency assays that provide for greater certainty and margins of safety in the use of products from different manufacturers.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: November 26, 2013
    Assignee: CNSS IP Holdings, Inc
    Inventor: Charles N. S. Soparkar
  • Patent number: 8592480
    Abstract: The invention relates to an aqueous liquid composition of calcium acetate, sweetener, and taste masking agent. Also provided is a method for binding phosphorus within the gastrointestinal tract of an individual by administering to the individual an aqueous solution of at least calcium acetate.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: November 26, 2013
    Assignee: Lyne Laboratories, Inc.
    Inventor: Stephen C. Tarallo
  • Patent number: 8591938
    Abstract: The invention relates to an aqueous liquid composition of calcium acetate, sweetener, and taste masking agent. Also provided is a method for binding phosphorus within the gastrointestinal tract of an individual by administering to the individual an aqueous solution of at least calcium acetate.
    Type: Grant
    Filed: July 20, 2007
    Date of Patent: November 26, 2013
    Assignee: Lyne Laboratories, Inc.
    Inventor: Stephen C. Tarallo
  • Patent number: 8586076
    Abstract: This invention relates to fat containing consumable food products comprising ?-cyclodextrin. The food products have reduced levels of bioavailable fat but have substantially the same fat, cholesterol and caloric content as a like food without ?-cyclodextrin. The invention also relates to methods for reducing the bioavailability of fats in fat containing food products without reducing caloric intake as determined by bomb calorimetry and to methods for increasing high density lipoproteins in a subject and reducing or controlling weight by administering the food products of this invention.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: November 19, 2013
    Assignee: SOHO Flordis International Pty Ltd
    Inventors: Joseph D. Artiss, Catherine Jen
  • Patent number: 8580295
    Abstract: A carbohydrate mixture for dietetic foods and pharmaceuticals is provided. The carbohydrate mixture comprises two different, substantially soluble carbohydrate components A and B, which remain undigested in the gastrointestinal tract and enter the large intestine without being resorbed. Carbohydrate component A may comprise at least one monosaccharide or of at least one oligosaccharide (disaccharide to hexasaccharide) or a mixture of two or more of these saccharides. Carbohydrate component B may comprise a polysaccharide (from heptasaccharide onwards) or a mixture of two or more polysaccharides. Carbohydrate component A=5 to 95 wt-% and carbohydrate component B=5 to 95 wt-% of the sum of the carbohydrate components A+B (=100 wt-%), and at least 80 wt-% of the carbohydrates/saccharides of both carbohydrate components have a prebiotic effect. The carbohydrate mixtures have not only a nutritive effect but they also stimulate health-promoting microorganisms present in the natural flora of the large intestine.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: November 12, 2013
    Assignee: N.V. Nutricia
    Inventors: Gunther Sawatzki, Bernd Stahl
  • Patent number: 8580296
    Abstract: Compositions and methods to improve the pharmacokinetic profile of S-Adenosylmethionine (SAMe) are provided, as are methods of treating various disorders using SAMe formulations with improved pharmacokinetic profiles. More specifically, the invention is directed to methods of treating a disease or disorder in a subject and/or improving the nutritional status of a subject by administering formulations exhibiting improved pharmacokinetic profiles of exogenous SAMe. The method also includes the step of orally administering compositions of the invention to the subject once per day after overnight fast; that is prior to food intake in the morning.
    Type: Grant
    Filed: December 13, 2012
    Date of Patent: November 12, 2013
    Assignee: Methylation Sciences International SRL
    Inventors: Nancy Harrison, I. David MacDonald, Aniko Takacs-Cox, Robert Miller
  • Patent number: 8580557
    Abstract: The present invention relates to a casein hydrolysate containing free amino acids and in vivo indigestible peptides having minimally suppressed in vivo enzymatic digestibility, and expected to express functions, such as hypotensive effect, in living organism, and to a method for preparing such a hydrolysate, and use thereof. The casein hydrolysate of the present invention contains free amino acids and peptides, such as in vivo indigestible peptides including Xaa-Pro and Xaa-Pro-Pro, obtained by hydrolyzing animal milk casein to have an average chain length of not longer than 2.1 in terms of the number of amino acid residues, and has ACE inhibitory activity or hypotensive effect.
    Type: Grant
    Filed: September 1, 2010
    Date of Patent: November 12, 2013
    Assignee: Calpis Co., Ltd.
    Inventors: Naoyuki Yamamoto, Seiichi Mizuno, Takanobu Gotou, Keiichi Matsuura, Tadashi Shinoda, Hideo Nishimura
  • Patent number: 8575142
    Abstract: To inhibit production of adipocytokines, in particular, adipocytokines that elicit insulin resistance and to prevent onset of pathosis caused by the insulin resistance or ameliorate the pathosis, the present invention provides an agent or a food or drink which contains a compound having a lophenol skeleton, or an organic solvent extract or a hot water extract of a Liliaceae plant or, a fraction thereof containing the compound as an active ingredient.
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: November 5, 2013
    Assignee: Morinaga Milk Industry Co., Ltd.
    Inventors: Miyuki Tanaka, Eriko Misawa
  • Patent number: 8574619
    Abstract: A method of reducing the cholesterol level of a subject by administering to that subject quercetin, vitamin C, vitamin B3, and statin.
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: November 5, 2013
    Assignee: Quercegen Pharmaceuticals, LLC
    Inventor: Thomas Christian Lines
  • Patent number: 8568773
    Abstract: The invention described herein provides a preparation comprising a non-mammalian derived mixture of serine glycerophospholipid conjugates with a specific content and specific conjugation patterns of LA, linolenic acid (alpha-linolenic acid, gamma-linolenic acid) DHA and EPA which depend on utilizing different sources of lipids, and uses of such preparations.
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: October 29, 2013
    Assignee: Enzymotec Ltd.
    Inventors: Gai Ben Dror, Dorit Platt, Orly Farkash, Rassan Zuabi, Zohar Bar-On, Avidor Shulman, Dori Pelled, Yael Richter
  • Patent number: 8569383
    Abstract: A preparation for creating a clearing feeling in a pharyngeal cavity and nasal cavity comprising a rhinologically active substance of formula (I): In formula (I), variable x and substituents R1, R2 and R3 have the following meanings: x is 0 or 1, R1 denotes an alkyl group having 1 to 4 carbon atoms, R2 denotes a methyl or ethyl group, and R3 denotes a monocyclic saturated carbon system having 5, 6, 7 or 8 carbon atoms that can be unsubstituted or substituted with further alkyl groups having 1 to 4 carbon atoms or alkenyl groups having 2 to 4 carbon atoms. The compound of formula (I) can be mixed with one or more other flavor substances or aroma substances. The preparation can be an oral care composition, such as a toothpaste or a mouth wash.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: October 29, 2013
    Assignee: Symrise AG
    Inventors: Horst Surburg, Arnold Machinek, Hubert Loges
  • Patent number: 8568767
    Abstract: The present invention provides a chewable composition containing granules of water-soluble dietary fiber. The chewable composition has highly agreeable organolpetic properties and is consumable without the need of an ingestion aid.
    Type: Grant
    Filed: January 9, 2013
    Date of Patent: October 29, 2013
    Assignee: Novartis AG
    Inventors: Nils William Ahlgren, Ronald Lee Dahl, Monte Lee Friesen, Alexander Mark Schobel
  • Patent number: 8563045
    Abstract: Hydrolyzed collagen type II powder compositions for inducing cartilage formation in an individual, method of preparing the compositions and use of the compositions in treating connective tissue disorder, replenishing skin viscoelasticity. The compositions are administered through an orally ingestible delivery medium for absorption into the gastrointestinal tract. The compositions are administered through a topical delivery medium for absorption into a dermis of the individual.
    Type: Grant
    Filed: September 13, 2010
    Date of Patent: October 22, 2013
    Assignee: Biocell Technology, LLC
    Inventor: Suhail Ishaq
  • Patent number: 8562952
    Abstract: Various embodiments of the invention disclosed herein include methods of inducing satiety a mammal in need thereof. Also disclosed are methods of inducing satiety in an obese mammal. Additionally disclose are method of suppressing appetite in a mammal in need thereof. Further disclosed are methods of treating obesity. The methods described herein involve the administration of serotonin, a serotonin agonist or a serotonin re-uptake inhibitor to the mammal.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: October 22, 2013
    Assignee: Cedars-Sinai Medical Center
    Inventor: Henry C. Lin
  • Patent number: 8563029
    Abstract: Compositions (including pharmaceutical compositions, foods, supplements, toys and treats) comprising a microbial exopolysaccharide are provided as well as methods for preventing or reducing diarrhea in a mammal wherein the method comprises administering a therapeutically amount of a microbial exopolysaccharide to a mammal in need thereof.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: October 22, 2013
    Assignee: Hill's Pet Nutrition, Inc.
    Inventors: Wai Cheuk, Christina Khoo
  • Patent number: 8557275
    Abstract: Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and/or rheumatoid arthritis have been found using a mixture of fish oil and fish oil derived, choline based, phospholipid bound fatty acid mixture including polyunsaturated EPA and DHA either alone or in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.
    Type: Grant
    Filed: April 4, 2011
    Date of Patent: October 15, 2013
    Assignee: U.S. Nutraceuticals, LLC
    Inventors: John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
  • Patent number: 8557274
    Abstract: Compositions which provide slowly digestible starch and a source of fermentable dietary fiber. Microparticles in which starch is entrapped in a crosslinked matrix to provide dietary benefit. Such microparticles are used to deliver glucose to targeted regions in the small intestine for beneficial physiological effects, and fermentable dietary fiber to the colon to improve colon health and to treat diseases of the colon. Microparticles can be employed to selectively deliver fermentable dietary fiber to targeted portions of the colon. A method for making the microparticles is provided as well as methods for using the microparticles for controlled digestion of starch on ingestion in the small intestine and methods for using the microparticles to deliver dietary fiber. The microparticles with entrapped starch provide a low glycemic index and extended glucose release in food products and food ingredients.
    Type: Grant
    Filed: December 6, 2006
    Date of Patent: October 15, 2013
    Assignees: Purdue Research Foundation, Rush University Medical Center
    Inventors: Bruce R. Hamaker, Mahesh Venktachalam, Genyi Zhang, Ali Keshavarzian, Devin J. Rose
  • Patent number: 8551542
    Abstract: Embodiments of the invention generally relate to methods and supplements for improving the health of human beings.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: October 8, 2013
    Inventors: Amy L. Heaton, Mitchell K. Friedlander, Dennis Gay
  • Patent number: 8551515
    Abstract: Compositions and methods to improve the pharmacokinetic profile of S-Adenosylmethionine (SAMe) are provided, as are methods of treating various disorders using SAMe formulations with improved pharmacokinetic profiles. More specifically, the invention is directed to methods of treating a disease or disorder in a subject and/or improving the nutritional status of a subject by administering formulations exhibiting improved pharmacokinetic profiles of exogenous SAMe. The method also includes the step of orally administering compositions of the invention to the subject once per day after overnight fast; that is prior to food intake in the morning.
    Type: Grant
    Filed: December 13, 2012
    Date of Patent: October 8, 2013
    Assignee: Methylation Sciences International SRL
    Inventors: Nancy Harrison, I. David MacDonald, Aniko Takacs-Cox, Robert Miller
  • Patent number: 8545892
    Abstract: Sustained-released beads providing active ingredients over an extended period of time to an individual orally ingesting the sustained release beads. The sustained-release beads can be part of a suspension wherein the sustained-release beads are suspended and evenly dispersed in the suspension. Binding agents are used to form the structural framework of the sustained released beads and retain the active ingredients without chemical or electrical bonding. The components of the dispersion medium are GRAS designated, making the suspension suitable for use as a food product.
    Type: Grant
    Filed: June 26, 2009
    Date of Patent: October 1, 2013
    Assignee: Nano Pharmaceutical Laboratories, LLC
    Inventor: Robert Niichel
  • Patent number: 8545870
    Abstract: The invention concerns a medicinal tablet to be sucked made with boiled sugar of solid consistency designed to dissolve in the buccal cavity, comprising at least an active principle. The invention is characterized in that it further comprises at least a matrix agent for slowing down the release of the active principle(s) which therefore remain in prolonged contact with the region of the mouth and the pharynx, the dissolving time in the buccal cavity being at least 15 minutes.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: October 1, 2013
    Assignee: Pierre Fabre Medicament
    Inventors: Pierre Dupinay, Robert Torres, Christine Capon
  • Patent number: 8541046
    Abstract: A novel canola protein isolate of predominantly 2S canola protein and having improved solubility properties, has an increased proportion of 2S canola protein and a decreased proportion of 7S canola protein. The novel canola protein isolate is formed by heat treatment of aqueous supernatant from canola protein micelle formation and precipitation, to effect precipitation of 7S protein which is sedimented and removed.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: September 24, 2013
    Assignee: Burcon NutraScience (MB) Corp.
    Inventors: Martin Schweizer, Brent E. Green, Kevin I. Segall, Randy Willardsen
  • Patent number: 8541018
    Abstract: The invention relates to a liquid vehicle that can be used to create suspensions and/or solutions of liquid or powdered medications. The vehicle is thixotropic and has improved stability and rheologic characteristics. Vehicles of the invention include an aqueous medium and a suspending agent comprising a polysaccharide having at least 50% glucose repeating saccharide units and at least 90% alpha linkages. The polysaccharide can be a starch, modified starch, or glycogen. The aqueous medium and individual components of the vehicle provide a palatable and easily ingested drug preparation. The invention also provides a vehicle containing an aqueous medium, suspending agent comprising a polysaccharide having at least 50% glucose repeating saccharide units and at least 90% alpha linkages, buffer, and artificial sweetener, the combined suspending vehicle having a pH of about 3 to about 10 and an osmolality of 300 mOmsol or less.
    Type: Grant
    Filed: August 11, 2011
    Date of Patent: September 24, 2013
    Assignee: Fagron, Inc.
    Inventors: Joshua Radke, Michael Jones, Martin Erickson
  • Patent number: 8535659
    Abstract: The present invention relates to different nutritional supplements to be administered to, or taken by, pregnant women during the first, second and third trimesters of pregnancy.
    Type: Grant
    Filed: May 21, 2009
    Date of Patent: September 17, 2013
    Assignee: Argent Development Group, LLC
    Inventors: John C. Morrison, Kenneth R. Greathouse
  • Patent number: 8535660
    Abstract: The present invention relates to different nutritional supplements to be administered to, or taken by, pregnant women during the first, second and third trimesters of pregnancy.
    Type: Grant
    Filed: November 7, 2011
    Date of Patent: September 17, 2013
    Assignee: Argent Development Group, LLC
    Inventors: John C. Morrison, Kenneth R. Greathouse
  • Patent number: 8523975
    Abstract: Salts of mineral nutrients stabilized with amino acids and/or ammonium salt, product and food supplement in which they are included and procedures of obtention, where the salts are obtained with anions of organic acids or inorganic anions and metallic cations associated with amino acids and/or ammonium salt, in which the invention introduces its general structure: {[Ac]n?·Men+?n[Amino acid and/or ammonium salt]}·xH2O Where ? represents a covalent dative bond, These new compounds have better taste and more solubility in water, making them more bioavailable.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: September 3, 2013
    Inventors: Eduardo Walter Ettlin, Jose Ruben Boccio, Adrian Tomas De Paoli, Edgardo Adrian Hager, Pablo Adrian De Paoli
  • Patent number: 8524269
    Abstract: The present invention provides oral dosage compositions, and methods of making thereof, which contain an edible oil, preferably containing an omega-3 fatty acid, and admixed therein one or more water soluble vitamins and/or minerals, for example vitamins B6, B9, and/or B12. The present invention also provides a method of making the composition comprising mixing the edible oil and one or more water-soluble vitamins and/or minerals to form a suspension or emulsion of the water-soluble vitamins and/or minerals in the edible oil. The mixture can be inserted into capsules, gelcaps, or caplets for oral consumption. An additional aspect of the invention is that the edible oil can coat particles of the water-soluble vitamins and/or minerals, which may preferably provide the vitamins and/or minerals improved absorption in the body due to increased resistance to degradation in the acidic environment of the stomach.
    Type: Grant
    Filed: November 7, 2011
    Date of Patent: September 3, 2013
    Assignee: PBM Pharmaceuticals, Inc.
    Inventors: Jack H. Schramm, James W. McGrath, Jr.
  • Publication number: 20130224279
    Abstract: The current invention is related to a novel process for the production of aqueous suspensions of micro and nanoparticles of calcium salts smaller than 10 ?m particle size, along with a method to enrich nutritional, nutraceutical, and pharmaceutical beverages with calcium salts. In the process, an aqueous suspension of calcium salt is subjected to pressurization with critical, subcritical, or supercritical carbon dioxide to increase the solubility of the calcium salt, which has a particle size greater than 30 ?m. The resulting solution is expanded through a nozzle to generate a calcium salt suspension of micro and nanoparticles that is imperceptible to sight and taste.
    Type: Application
    Filed: December 8, 2010
    Publication date: August 29, 2013
    Applicant: UNIVERSIDAD DEL VALLE
    Inventors: Gustavo Eduardo Bolanos Barrera, Isabel Maria Mejia Villareal
  • Patent number: 8518448
    Abstract: Sustained-released beads providing active ingredients over an extended period of time to an individual orally ingesting the sustained release beads. The sustained-release beads can be part of a suspension wherein the sustained-release beads are suspended and evenly dispersed in the suspension. Binding agents are used to form the structural framework of the sustained released beads and retain the active ingredients without chemical or electrical bonding. The components of the dispersion medium are GRAS designated, making the suspension suitable for use as a food product.
    Type: Grant
    Filed: April 18, 2011
    Date of Patent: August 27, 2013
    Inventor: Robert Niichel