Candy, Candy Coated Or Chewing Gum Patents (Class 424/440)
-
Publication number: 20080181934Abstract: Pharmacologically effective amounts of a medication are delivered in pleasant tasting delivery vehicles, including gelatins and candies. Mechanisms for the reduction in surface area of noxious taste-imparting aspects of conventional medicines, and dilutive effects of positive masking elements for such medicines, especially products for inducing children to take medicines, are taught—in combination with processes and products thereby.Type: ApplicationFiled: October 31, 2007Publication date: July 31, 2008Inventor: Michelle Chow
-
Publication number: 20080181933Abstract: A chewing gum composition including a water insoluble base portion; a water soluble portion; and a therapeutically effective amount of varenicline or its pharmaceutical acceptable salt thereof. A method for reducing nicotine addiction and aiding in the cessation or lessening of tobacco use in an individual by administering to an oral cavity of an individual a chewing gum composition including an effective amount of varenicline or its pharmaceutical acceptable salt thereof; and chewing the gum composition to cause the varenicline or its pharmaceutical acceptable salt thereof to be released from the chewing gum composition into the oral cavity of the individual. A method of manufacturing a chewing gum composition.Type: ApplicationFiled: March 9, 2006Publication date: July 31, 2008Inventors: Barbara Alice Johnson, Carl Bernard Ziegler
-
Publication number: 20080175876Abstract: Disclosed herein are novel chitinase polypeptides and nucleic acids encoding the polypeptides. Also disclosed are related vectors, host cells, compositions, and uses.Type: ApplicationFiled: January 14, 2008Publication date: July 24, 2008Applicant: Academia SinicaInventors: Jei-Fu Shaw, Yu-Ting Chen, Lien-Hua Hsu
-
Patent number: 7396546Abstract: An anti-microbial composition is provided. The anti-microbial composition includes a first ingredient obtainable from ginger, a second ingredient obtainable from green tea, an optional third ingredient available from turmeric, and, optionally, an acceptable carrier. Also provided are methods of reducing, treating or preventing at least one symptom or adverse effect of microbial infection in a patient. The methods include the step of administering to the patient prior to expected exposure to a microbe, concurrently with exposure to a microbe, or after exposure to a microbe, an effective amount of a composition of the invention.Type: GrantFiled: February 6, 2003Date of Patent: July 8, 2008Assignee: The Quigley CorporationInventor: Richard A. Rosenbloom
-
Publication number: 20080160066Abstract: Taught are pharmaceutical compositions comprising at least one phospholipid having at least one docosahexaenoyl (DHA) residue, such as a lecithin-DHA-type phospholipid, and methods for treating or preventing respiratory failure of a patient comprising administering these pharmaceutical compositions to a patient in need of such treatment or prevention.Type: ApplicationFiled: March 3, 2008Publication date: July 3, 2008Inventors: Gerard Pieroni, Thierry Coste
-
Patent number: 7393542Abstract: An agent for treating or preventing allergic disease comprising, as an active ingredient, a treated product of peanut seed coats.Type: GrantFiled: February 15, 2002Date of Patent: July 1, 2008Inventors: Akio Yoshihara, Tomihisa Ohta, Takahiro Moro, Kaoru Hirose
-
Patent number: 7390518Abstract: A composition in the form of a chewing gum composition or a confectionery composition containing a stain removing complex of a stain removing agent and a cyclodextrin compound and methods of preparing and using the same to remove stains from dental material including teeth.Type: GrantFiled: July 11, 2003Date of Patent: June 24, 2008Assignee: Cadbury Adams USA, LLCInventors: Petros Gebreselassie, Shiuh John Luo, Navroz Boghani
-
Publication number: 20080138384Abstract: Disclosed is a hair growth stimulant for oral use comprising at least one member selected from the group consisting of plants of the genus Orthosiphon in the family Lamiaceae, plants of the genus Vitex L. in the family Verbenaceae, and extracts thereof; and a food comprising the hair growth stimulant for oral use.Type: ApplicationFiled: February 12, 2008Publication date: June 12, 2008Inventors: Kouichi Nakaoji, Masahiro Matsuura, Naoko Hayashi, Toyoyuki Nishi
-
Publication number: 20080113004Abstract: Provided are methods of treating pain, including neuropathic pain, in human and veterinary individuals. These methods employ locally administrable pharmaceutical gallium compositions, including pharmaceutical gallium compositions suitable for administration to the skin and mucous membranes. The compositions comprise pharmaceutically acceptable gallium compounds, such as gallium maltolate or gallium nitrate, together with pharmaceutically acceptable carriers suitable for local administration, including those suitable for topical administration. The administration of such compositions provides relief from pain, itching, allodynia, hyperalgesia, and related symptoms.Type: ApplicationFiled: November 7, 2007Publication date: May 15, 2008Inventor: Lawrence R. Bernstein
-
Publication number: 20080102102Abstract: The invention provides methods and compositions comprising an anti-cholinergic agent for decreasing saliva production and treating sialorrhea.Type: ApplicationFiled: January 19, 2006Publication date: May 1, 2008Applicant: NEUROHEALING PHARMACEUTICALS, INC.Inventors: Marcelo Merello, Neal M. Farber, Eyal S. Ron
-
Patent number: 7351438Abstract: The invention is a chewing gum formulation in powder form, a process for producing it, and a chewing gum in tablet produced by direct compression of a the chewing gum formulation in powder form that is characterized by a chewability that remains unchanged throughout the chewing period.Type: GrantFiled: May 13, 2003Date of Patent: April 1, 2008Assignee: Gum Base Co. S.p.A.Inventors: Giuseppe Sozzi, Fabio Allasia
-
Patent number: 7351425Abstract: A gum, lollipop and lozenge having at least two separate components, with at least one of such components containing amounts of herbal, medicinal and/or mineral elements or combinations thereof.Type: GrantFiled: March 17, 2005Date of Patent: April 1, 2008Inventor: Jack Barreca
-
Publication number: 20080075674Abstract: A cough suppressor according to the present invention includes a chewable inner layer having a predetermined flavor. Preferably, the inner layer is chewing gum. The cough suppressor also includes an active layer situated outside the inner layer and that includes a cough suppressant. In addition, a buffer layer completely separates the inner layer from the active layer. The buffer layer includes a predetermined flavor and ensures that the active layer does not interfere with the flavor of the inner layer. According to another embodiment, a cough suppressant system includes the cough suppressor and one or more auxiliary flavor tablets, each of which includes a desirable flavor such that this flavor may be selectively maintained long after the flavor of the inner layer is consumed. A cough suppressant liquid may be included for application to the flavor tablets.Type: ApplicationFiled: September 25, 2006Publication date: March 27, 2008Inventor: Brian D. DuPratt
-
Publication number: 20080069874Abstract: Kits providing a combination of one or more pharmaceutical information comprising one or more agent(s) for the treatment or alleviation of symptoms commonly associated with a cold and an immunonutritional composition comprising immunonutritional agent and methods of using these kits are described . The kits provide both the pharmaceutical agent(s) and the immunonutritional agent in a convenient form for administration. The kit typically includes instruction for coordinating the administration of the pharmaceutical formulation with the administration of the immunonutritional composition. The preferred immunonutritional agents are compounds that contain a pharmaceutically acceptable form of zinc, such as zinc acetate, zinc gluconate, zinc gluconate glycine, and zinc sulfate. Preferably the kit contains multiple dosage forms containing the immunonutritional composition. In the most preferred embodiment, the immunonutritional composition is in the form of a lozenge.Type: ApplicationFiled: January 12, 2007Publication date: March 20, 2008Inventors: Mischelle Hall, Alan Roberts, Matthew Heil
-
Publication number: 20080057111Abstract: A herbal formulation for prevention and/or treatment of flu. The formulations comprise of plant or plant extract together with vitamins and conventional additives. The plant is isatis indigotica, or strobilanthes cusia or the mixture thereof The formulations are in the form of tablet, powder, capsule, liquid or gum. Preferably, the formulations are in the manner of effervescent or chewing gum.Type: ApplicationFiled: August 29, 2006Publication date: March 6, 2008Inventor: Lixian Jiang
-
Patent number: 7329416Abstract: Disclosed is a method for enhancing absorption of a medicament that is suitable for administering transmucosally to a subject by providing an environment of the administration with a suitable pH. A medicament of propranolol suitably administered sublingually is provided. The medicament of propranolol can be used for treating diseases related to the cardiovascular system.Type: GrantFiled: September 7, 2005Date of Patent: February 12, 2008Assignee: The Chinese University of Hong KongInventors: Sing Sum Moses Chow, Yan-feng Wang, Zhong Joan Zuo
-
Publication number: 20070286821Abstract: In a personal care daily practice, common human malodor in breath can be treated and eliminated or substantially reduced through the use of a treatment comestible, lozenge, chewing gum or scraper prepared by combining a hardenable natural or artificial sweetener or gum base with an amount of activated carbon effective in reducing such malodors.Type: ApplicationFiled: May 31, 2007Publication date: December 13, 2007Inventor: David M. Phillips
-
Publication number: 20070286819Abstract: Methods of improving the bioavailability of ethinyl estradiol by orally administering to a patient a solid dosage form containing ethinyl estradiol or prodrug thereof where that dosage form releases at least some of the ethinyl estradiol or prodrug thereof in the oral cavity for absorption through the oral mucosa to treat the patient for a predetermined indication such as, for example, hormone replacement therapy or contraception. The solid dosage forms may be selected from, among others, chewable tablets, fast melt tablets, films, dissolving films, mucoadhesive tablets, lozenges, and chewing gum.Type: ApplicationFiled: June 8, 2007Publication date: December 13, 2007Applicant: WARNER CHILCOTT COMPANY, INC.Inventors: Tina DeVries, Brian McNamee
-
Publication number: 20070281000Abstract: The present invention provides stable pharmaceutical compositions comprising moisture sensitive drugs, in particular an angiotensin converting enzyme (ACE) inhibitor such as Cilazapril, as the active ingredient, and at least one pharmaceutical excipient, wherein the active pharmaceutical ingredient is wet granulated with a solution of at least one pharmaceutical excipient, and methods for preparing such stable pharmaceutical compositions.Type: ApplicationFiled: June 2, 2006Publication date: December 6, 2007Inventor: Michael Fox
-
Publication number: 20070274927Abstract: A slow-dissolving troche with polyol molecules is disclosed. It may be an adherent troche, preferably adhered to teeth or gums or cheek with acacia gum, or a lollipop or child's pacifier. Consumers are instructed to use the troches at the end of each day and after each meal, at least four times per day to benefit oral health, particularly caries, gingivitis, periodontitis, ear infections, sinus infections, halitosis and risk of Streptococcus mutans infecting their blood from their mouths. The polyol molecules are preferably xylitol. The troches may be made with a bi-layer tablet press rounded on one side and flat on the other, preferably using acacia gum in the flat side layer for adhesion.Type: ApplicationFiled: May 4, 2007Publication date: November 29, 2007Inventors: Jeffrey T. Haley, Steven Edwards
-
Publication number: 20070269494Abstract: Compositions and methods for enhancing the absorption of active agents across the mucosa of animal subjects are provided. Methods of administration and appropriate dosage forms are also provided.Type: ApplicationFiled: May 18, 2007Publication date: November 22, 2007Inventor: Chung Shih
-
Publication number: 20070269493Abstract: This invention provides edible compositions comprising pharmaceutically or nutraceutically active agents in particulate form homogeneously dispersed in a fat matrix, such as chocolate or chocolate compound coating.Type: ApplicationFiled: November 17, 2006Publication date: November 22, 2007Applicant: DELAVAU L.L.C.Inventor: Kevin W. Lang
-
Publication number: 20070269492Abstract: Coated oral dosage forms for the delivery of nicotine in any form to a subject by rapid intraoral delivery of nicotine comprising at least one core, nicotine in any form and/or a nicotine mimicking agent, at least one coating layer and optionally at least one or more other additives, wherein said at last one coating layer is buffered, whereby is used at least trometamol as buffering agent. Also contemplated is a method for the delivery of nicotine in any form, a method for the reduction of the urge to smoke or use tobacco as well as a method for producing said coated product and the use of the same for obtaining a rapid intraoral uptake of nicotine.Type: ApplicationFiled: June 1, 2006Publication date: November 22, 2007Inventors: Per Steen, Darek Dymitrowicz, Asa Waltermo, Roland Olsson, Katarina Lindell
-
Publication number: 20070269386Abstract: A pharmaceutical oral formulation for delivering nicotine in any form to a subject by transmucosal uptake in the oral cavity comprising nicotine in any form, wherein said oral formulation is buffered with at least trometamol. Also contemplated is a method for the oral delivery of nicotine in any form, a method for the reduction of the urge to smoke or use tobacco as well as methods for manufacturing the oral formulation, the use of the oral formulation for obtaining transmucosal uptake of nicotine in the oral cavity of a subject, and use of nicotine for the production of an oral formulation for the treatment of a disease selected from the group consisting of tobacco or nicotine dependence, Alzheimer's disease, Crohn's disease, Parkinson's disease, Tourette's syndrome, ulcerous colitis and post-smoking-cessation weight control.Type: ApplicationFiled: June 1, 2006Publication date: November 22, 2007Inventors: Per Steen, Darek Dymitrowicz, Andreas Hugerth, Asa Waltermo, Magnus Palsson, Roland Olsson, Fredrik Nicklasson, Anette Schluter, Kristina Thyresson, Seema K. Mody, Bengt Bosson, Katarina Lindell, Gregory Koll
-
Publication number: 20070248651Abstract: A vitamin, mineral, herbal, and micronutrient treatment for acne via support of the physiologic processes in the body which cause acne is disclosed. It is a targeted formula, designed specifically to address the causes of acne. This specific, unique formulation preferably in a gummy substrate for ease of administration, to induce a willingness on the part of the target population to take it, and to increase the bioavailability of the active ingredients. Other types of confection or edible vehicle can be used.Type: ApplicationFiled: July 7, 2006Publication date: October 25, 2007Inventors: Ellie Sawits, Peter C. Dea, Laura Tringale
-
Publication number: 20070237805Abstract: The present invention relates to chewing gum and confectionery compositions for improving the dental health of mammals, particularly humans. In particular, the compositions may include a gum base or carrier, sweetening agents, casein phosphopeptide-calcium phosphate (CPP-ACP) and food-grade acids. The compositions may be employed to remineralize the tooth surfaces of mammals, as well as impart acid resistance thereto.Type: ApplicationFiled: April 4, 2007Publication date: October 11, 2007Inventors: Doris Tancredi, Ding Ming, Samantha Holme
-
Publication number: 20070231368Abstract: The present invention provides pharmaceutical compositions and formulations comprising a therapeutically effectively of EDP-182 and the methods of formulation preparations. The present invention provides methods of treating bacterial infections by administering the pharmaceutical compositions to a subject in need of such treatment.Type: ApplicationFiled: March 29, 2007Publication date: October 4, 2007Applicant: ENANTA PHARMACEUTICALS, INC.Inventors: MICHELLE WANG, RONGQI SUN, YAT SUN OR, ZHE WANG
-
Publication number: 20070190090Abstract: Biofilm-responsive oral care products containing emulsion/sialagogue mixtures, provide the user with increased and prolonged saliva flow.Type: ApplicationFiled: February 5, 2007Publication date: August 16, 2007Applicant: WhiteHill Oral Technologies, Inc.Inventor: DALE G. BROWN
-
Publication number: 20070172511Abstract: A food product comprises an oligosaccharide composition that is digestion resistant or slowly digestible. The oligosaccharide composition can be produced by a process that comprises producing an aqueous composition that comprises at least one oligosaccharide and at least one monosaccharide by saccharification of starch, membrane filtering the aqueous composition to form a monosaccharide-rich stream and an oligosaccharide-rich stream, and recovering the oligosaccharide-rich stream. Alternatively, the oligosaccharide composition can be produced by a process that comprises heating an aqueous feed composition that comprises at least one monosaccharide or linear saccharide oligomer, and that has a solids concentration of at least about 70% by weight, to a temperature of at least about 40° C.Type: ApplicationFiled: December 14, 2006Publication date: July 26, 2007Inventors: Michael D. Harrison, Andrew J. Hoffman
-
Patent number: 7244455Abstract: A centerfill chewing gum composition having a shell portion and a centerfill portion, the centerfill portion containing an effective amount of a calcium-containing compound suspended therein.Type: GrantFiled: January 16, 2002Date of Patent: July 17, 2007Assignee: Warner-Lambert CompanyInventors: Jesse John Kiefer, Hector Olaya, Carolina Buitron Kellstein, Blake Henderson Glenn
-
Patent number: 7232581Abstract: The invention relates to a method for producing chewing gum granules. The method comprises at least the steps of feeding a gum composition including at least gum base into an extruder (2), pressurizing the gum composition in the extruder, extruding the gum composition through a die plate (5), and cutting the extruded gum composition in a liquid filled chamber (4). The extruded gum composition comprises at least 71% Wt, gum base and the cut granules are included in compressed gum tablets. The invention further relates to a chewing gum product, and to a chewing gum granulating system.Type: GrantFiled: July 1, 2003Date of Patent: June 19, 2007Assignee: Gumlink A/SInventors: Rikke Mikkelsen, Kaj Hovhave Nielsen, Niels Ravn Schmidt, Per Henrik Ertebjerg Christensen
-
Patent number: 7232572Abstract: A method of treating rosacea in a human in need thereof comprising administering to said human a tetracycline compound in an amount that is effective to treat rosacea, but has substantially no antibiotic activity.Type: GrantFiled: February 18, 2005Date of Patent: June 19, 2007Assignee: CollaGenex Pharmaceuticals, Inc.Inventor: Robert A. Ashley
-
Patent number: 7226613Abstract: Spherical capsule having a liquid core and a seamless solid shell surrounding the core, in which: the diameter of the capsule is in the range of 4-8 mm; the thickness of the shell is in the range of 20-200 ?m; the shell thickness to capsule diameter ratio is in the range of 0.004-0.04; the shell contains 70-90% (m/m) gelatin and 10-30% (m/m) plasticizer, based on the solids content of the shell; and the core has a flavoring content in the range of 1-100% (m/m), based on the total mass of the core.Type: GrantFiled: December 5, 2003Date of Patent: June 5, 2007Assignee: Symrise GmbH & Co. KGInventors: Birgit Schleifenbaum, Ines Voigt, Frank Aickele
-
Patent number: 7211267Abstract: A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective to treat acne but has substantially no antibiotic activity, without administering a bisphosphonate compound.Type: GrantFiled: April 5, 2002Date of Patent: May 1, 2007Assignee: CollaGenex Pharmaceuticals, Inc.Inventor: Robert A. Ashley
-
Patent number: 7208186Abstract: The present invention involves a novel chewing gum formulation and a method of making the same. The chewing gum formulation is used to form a final chewing gum composition which contains an active ingredient which is released from the chewing gum as the gum is masticated in the mouth of the user. The chewing gum made from the chewing gum composition of the present invention is initially a compressed body, such as a tablet, which quickly dissociates into a multiplicity of small pieces upon initial chewing followed by a reformation of the pieces into a coherent mass of chewing gum after a few seconds of chewing. Both the chewing gum formulation and the chewing gum composition are in the form of a free-flowing particulate which is capable of being directly compressed at high speed by a standard tableting machine into chewing gum tablets.Type: GrantFiled: April 24, 2003Date of Patent: April 24, 2007Assignee: SPI Pharma, Inc.Inventors: Gary T. Norman, Arun F. Amin
-
Patent number: 7182937Abstract: A composition for reducing dentinal hypersensitivity and remineralizing exposed dentinal surface and open dentinal tubules, comprising a non-aqueous carrier and a desensitizing amount of a desensitizing/remineralizing agent which consists essentially of a water soluble calcium salt and an incompatible ingredient which would otherwise react with the calcium salt. Upon contact with saliva when applied to an oral cavity, the desensitizing/remineralizing is then formed in situ by the reaction between the calcium salt and the incompatible ingredient, thereby remineralizing exposed dentinal surface and open dentinal tubules.Type: GrantFiled: October 10, 2001Date of Patent: February 27, 2007Assignee: Block Drug Company, Inc.Inventors: Jin Xu, Stephen W. Mruphy, Bala Nayar, Michael E. Trama
-
Patent number: 7163705Abstract: A method for producing a coated chewing gum product with accelerated absorption of medicaments through oral mucosa, as well as the chewing gum product so produced, is obtained by using a xylitol or sorbitol coating, or by adding a water-soluble alkaline material, such as a bicarbonate salt, to the chewing gum center, a coating on the center, or both. Coatings made with sorbitol or xylitol or gum centers that include sodium bicarbonate are particularly preferred.Type: GrantFiled: December 17, 2001Date of Patent: January 16, 2007Assignee: Wm. Wrigley Jr. CompanyInventors: Sonya S. Johnson, David G. Barkalow, Michael J. Greenberg, Gloria T. Sheldon
-
Patent number: 7138150Abstract: This invention concerns a method of making an anti-infective composition for oral administration using an agent selected from the group consisting of lactoferrin protein and lysozyme protein. The method comprises three steps. The nucleic acid, which encodes a lactoferrin or lysozyme protein, is expressed in a monocot seed. The protein is isolated from the seed. This protein isolation compromises greater than 3% of the total soluble protein in the monocot seed. The protein is then formulated for oral administration.Type: GrantFiled: August 13, 2003Date of Patent: November 21, 2006Assignee: Ventria BioscienceInventors: Ning Huang, Jianmin Huang, Delia R. Bethell
-
Patent number: 7115586Abstract: The invention provides a number of methods for enhancing the aqueous solubility of an active ingredient which is insoluble or sparingly soluble in water. In one preferred embodiment, solubilization of the active ingredient is enhanced by combining it with ?-cyclodextrin in an aqueous complexation medium comprising ?-cyclodextrin and a negatively- or positively-charged compound which forms an inclusion or non-inclusion complex with ?-cyclodextrin and its inclusion complexes.Type: GrantFiled: October 18, 2002Date of Patent: October 3, 2006Assignee: Decode Genetics EHF.Inventor: Thorsteinn Loftsson
-
Patent number: 7101579Abstract: The present invention provides a chewing gum composition containing an active ingredient. The preferred chewing gum composition comprises a plurality of granules comprising a mixture of a powdered chewing gum base and a selected amount of a powdered active ingredient, said powdered chewing gum base and powdered active ingredient being mixed together within said granules. Additives may be mixed in the granules or may coat the granules. The preferred form is a tablet containing a controlled dosage form of the active ingredient.Type: GrantFiled: March 8, 2004Date of Patent: September 5, 2006Assignee: Deseret Laboratories, Inc.Inventors: Narayan K. Athanikar, Scott A. Gubler
-
Patent number: 7090832Abstract: The invention pertains to cooling agents comprising N-substituted p-menthane-3-carboxamides, menthyl acetate and solubilizer, and methods for making the cooling agents. The invention also concerns pharmaceutical compositions comprising the cooling agents, including tablets, suspensions and liquid solutions having active pharmaceutical agents for treating upper gastrointestinal tract distress, and methods for treating upper gastrointestinal tract distress in humans.Type: GrantFiled: October 17, 2002Date of Patent: August 15, 2006Assignee: Firmenich SAInventors: John Zanone, Roger E. Stier
-
Patent number: 7087255Abstract: A coated chewing gum is provided that includes a metal salt. The salt can be located in the gum center, coating, or both. A metal salt is provided in a therapeutically effective amount to reduce or eliminate oral malodors associated with bad breath. A variety of metal salts are possible. The coating may also include a surfactant and an edible oil.Type: GrantFiled: December 14, 2001Date of Patent: August 8, 2006Assignee: Wm. Wrigley Jr. CompanyInventors: Gordon N. McGrew, James R. Maxwell, Henry T. Tyrpin, Michael J. Greenberg, David W. Record
-
Patent number: 7084132Abstract: A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, ?-cyclodextrin. The complexed cyclodextrin artemisinin formulation shields the peroxide portion of the artemisinin backbone from hydrolytic decomposition rendering it stable in solution. Artelinic acid and cyclodextrin are placed into contact with one another to yield a 2:1 molecular species. Artesunic acid and cyclodextrin yield a 1:1 molecular species. The complexed cyclodextrin artemisinin formulation is effective for the treatment of malaria and is stable in solution for long periods of time.Type: GrantFiled: April 25, 2005Date of Patent: August 1, 2006Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Mark G. Hartell, Apurba K. Bhattacharjee, Rickey P. Hicks, John E. VanHamont, Wilbur K. Milhous
-
Patent number: 7078052Abstract: Methods and chewing gums for delivering a medicament or agent to an individual are provided. The chewing gum includes a medicament or agent. The medicament or agent is present within the chewing gum composition (the water soluble portion and/or insoluble base portion). It has been found that by chewing the gum, the medicament or agent is released from the chewing gum. Continuing to chew the chewing gum creates a pressure within the buccal cavity forcing the agent or medicament directly into the systemic system of the individual through the oral mucosa contained in the buccal cavity. This greatly enhances the absorption of the drug into the systemic system as well as the bioavailability of the drug within the system.Type: GrantFiled: December 22, 2003Date of Patent: July 18, 2006Assignee: Wm. Wrigley Jr. CompanyInventors: Ronald L. Ream, Christine L. Corriveau, William J. Wokas, Thomas M. Tongue, Jr., Michael J. Greenberg
-
Patent number: 7067150Abstract: The present invention provides oral delivery systems for functional ingredients, such as drugs, nutritional supplements, botanicals, and vitamins. The delivery systems comprise an ingestible matrix within which the functional ingredient(s) are substantially uniformly and completely dispersed and in which degradation of the functional ingredient(s) is minimised. The matrix comprises 1) one or more carbohydrate; 2) one or more sugar, sugar syrup and/or sugar alcohol; 3) one or more hydrocolloid; 4) one or more polyhydric alcohol; 5) one or more source of mono- or divalent cations, and 5) water. The combination of carbohydrate and hydrocolloid in the matrix ensures that the delivery system readily retains the solvent component and thereby prevents separation of the solvent from other components of the matrix. The invention also provides methods of preparing and using the delivery systems.Type: GrantFiled: March 25, 2003Date of Patent: June 27, 2006Assignee: Scepter Holdings, Inc.Inventors: Michael Farber, Jonathan Farber
-
Patent number: 7063858Abstract: The invention relates to a sweet of boiled sugar type exhibiting a rough texture intended for the treatment of halitosis as well as process for making the same and a method for treating halitosis using the same.Type: GrantFiled: January 11, 2002Date of Patent: June 20, 2006Assignee: Roquette FreresInventors: Marie-Hèlène Saniez, Guillaume Ribadeau-Dumas, Céline Taillez
-
Patent number: 7041311Abstract: The present invention is directed to products that promote saliva generation in the mouth through the use of various food grade acceptable acids. The products that enhance saliva production are preferably foods that are consumed in the mouth over a period of time of a minute or longer such as chewing gums, breath films, toothpaste and lozenges.Type: GrantFiled: February 28, 2003Date of Patent: May 9, 2006Assignee: International Flavors & Fragrances Inc.Inventors: Brian T. Grainger, Derek Richard Farley, Ana Paula Ventura da Costa Lopes
-
Patent number: 7015232Abstract: The present invention is directed to ACE inhibitor-containing compositions stabilized by the presence of magnesium oxide. Preferably, the ACE inhibitor, quinapril, is protected from certain forms of degradation when prepared in a pharmaceutical composition consisting essentially of magnesium oxide as the stabilizing agent. The presence of magnesium oxide also lends itself to favorable processing conditions during the manufacture of ACE inhibitor-containing compositions, especially processing by wet granulation.Type: GrantFiled: April 22, 2002Date of Patent: March 21, 2006Assignee: Warner-Lambert Company, LLCInventors: Jane Ellen Daniel, Michael Ray Harris, Gerard Clifford Hokanson, Jay Weiss
-
Cosmetic preparation of active substances with a synergistically increased radical protection factor
Patent number: 6989150Abstract: The inventive cosmetic preparation of active substances, as such as well as in combination with other active substances, protects the skin against free radical aggression in a particularly effective manner. The preparation consists of a bark extract of quebracho blanco which contains at least 90 wt. % of proanthocyanidine oligomers, a silkworm extract which contains the peptide cecropine, amino acids and a vitamin mixture, a non-ionic, cationic or anionic hydro-gel, phopholipids, a yeast disintegration product and cyclodextrines. The inventive preparation can contain additional active substances such as plant extracts of acerola, sea weed, citrus, bitter orange, cherry, papaya, tea, coffee beans, skin tree and angelica. The preparations have synergistically increased radical protection factors of up to 10,000. Cosmetic compositions containing said preparations have radical protection factors of between 40 and 400 according to the portion of the preparation.Type: GrantFiled: October 8, 1999Date of Patent: January 24, 2006Assignee: COTY B.V.Inventors: Karin Golz-Berner, Leonhard Zastrow -
Patent number: 6982098Abstract: The present invention relates to an agent that suppresses appetite and provides quick energy. According to at least one aspect of the present invention, a lollipop is provided that suppresses appetite and provides quick energy. The lollipop is made from a premixed herbal formula that is combined with a hard candy confection base. The herbal premixed formula includes the following active ingredients: Guarana PE 22%; CitriMax®; and L-Tyrosine. The herbal premix formula can also include Vitamin B6; and Vitamin B12 Cyanacobalamin. The premixed formula is added to a candy base that may include corn syrup, Maltodextrin, sugar, natural color and natural flavorings.Type: GrantFiled: May 26, 2004Date of Patent: January 3, 2006Assignee: Fun Unlimited Inc.Inventor: Michael P. Wenniger