Abstract: Neutral alpha amino diacid complexes of trace minerals and their use for animal nutrition.

Abstract: Improved particulate feed additives and methods are provided for enhancing feed utilization efficiency in a ruminant animal by adding to the feed of the animals a particulate feed additive comprising a nonionic surfactant to enhance the utilization of the feed by the animal and a sufficient amount of an antioxidant agent to substantially enhance the shelf life of the feed additive. The methods and compositions result in enhanced weight gain and/or milk production by the animal.

Abstract: The present invention relates to the treatment of gastrointestinal disease and/or cancer, and a method of weight gain, via the ingestion of polymeric compositions in humans, animals or birds in need of said treatment. The invention provides methods for the treatment of cancer, the treatment and/or prevention of gastrointestinal disease and/or infection and/or diarrhea and a method for increasing weight gain in humans, animals or birds comprising administering to said humans, animals or birds an effective amount of a pharmaceutical or veterinary composition or feed additive, comprising an effective amount of a polymer and/or copolymer, having the repeating polymeric unit (I) wherein R is H or alkyl, usually C1 to C4, or this unit in hydrated, hemiacetal or acetal form, together with a pharmaceutically or veterinarally acceptable carrier, diluent, adjuvant, excipient and/or controlled release system.

Abstract: The development and growth of oviparous species such as birds is enhanced by in ovo administration of an enteric modulator such as HMB. The enteric modulator is administered into the amnion, where it is then orally ingested by the subject. The enteric modulator enhances the enteric development of the subject prior to hatch, and enhances the growth of the animal before and after hatch.

Abstract: A mineral supplement or feed for ruminant animals, especially deer, contains effective amounts of sulfur and garlic to repel insects from the animals. By inducing the repellant into the animal via ingestion of the mineral supplement or feed, disease and stress in the animals as caused by the insects is reduced.

Abstract: Improved ivermectin-containing daily ration extruded feeds for domesticated household pets such as cats and dogs are provided so that a pet consuming the feeds receives quantities of ivermectin sufficient to establish and maintain substantially constant concentrations of the drug in the pet's bloodstream. The feeds are produced by extrusion with addition of minor quantities of ivermectin so as to uniformly distribute the drug throughout the extruded product. Ivermectin levels of from about 2-1500 &mgr;g/kg of extruded feed are preferred.

Abstract: The is invention is directed to a composition useful for assisting in supplying a warm-blooded animal with many of its nutritional needs. More specifically, this invention is directed to a composition whereby many of the vitamins, minerals, amino acids and cofactors are suspended in a matrix which when administered to a mammal provides substantial benefit.

Abstract: A process for increasing the percentage of active ingredient relative to non-active excipient in a compressible formulation, and also for reducing tablet size, by excluding an amount of the excipient and including in its place a reduced amount of a polysaccharide material.

Abstract: An antiseptic composition useful in destroying the infectivity of infectious proteins such as prions is disclosed. The antiseptic composition is preferably maintained at either a low pH of 4.0 or less or a high pH of 10.0 or more either of which allows for an environment under which the active component (which is preferably sodium dodecyl sulfate) destroys infectivity. The composition may be added to blood, blood products, collagen, tissues and organs prior to transplantation. The composition also may be added to livestock feed to denature any prions in the livestock. Methods of denaturing infectious proteins are also disclosed which method can use but do not require higher temperatures and long period of exposure.

Abstract: This invention provides a pigment-containing substance for feed additives consisting of a microorganism culture precipitate which contains a high concentration of carotenoid compounds. This pigment-containing substance for feed additives is resistant to oxygen, light and so on, and can be stably conserved for a long time period.

Abstract: The invention relates to feedstuff for economically useful animals such as, for example, chicken, pigs, calves and fish that are being raised. The inventive feedstuff contains functional additives. The feedstuff contains a pure finely divided cellulose additive and optionally a prebiotic additive.

Abstract: The present invention provides, amongst others, a means to overcome the problem of oxidative stress in the domestic cat and dog. There is provided a method for increasing the plasma vitamin E level in a cat or dog, the method comprising the step of administering to said cat or dog, an amount of Vitamin E sufficient to increase the plasma vitamin E level. There is also provided use of vitamin C in the manufacture of a dog or cat foodstuff for the prevention or treatment of a disorder which has a component of oxidative stress. The present invention utilizes an antioxidant cocktail to overcome the problem of oxidative stress in a cat or dog. Such cocktail can be used to prevent or treat a disorder which has a component of oxidate stress or to maintain, optimise or boost immunological response.

Abstract: Disclosed herein are methods of promoting weight control in a companion animal comprising orally administering one or more non-glyceryl derivatives of C17 or greater fatty acids. Also disclosed are methods for promoting weight control in a human comprising orally administering non-glyceryl derivatives of C17 or greater fatty acids, wherein the fatty acid derivatives do not cause the human to reduce food consumption. Further disclosed are methods for promoting weight control in a human or companion animal comprising orally administering lotus leaf extract.

Abstract: Enzyme feed supplements containing fungal cellulase produced by Trichoderma viride are specially adapted for increasing protein digestability of dairy cow and cattle feed. Preferred embodiments of the present invention include enzyme formulations adapted for application to corn and enzyme formulations adapted for application to grain sorghum, to which is added Trichoderma viride cellulase. An increase in protein digestability has been evidenced by increased protein content of milk and increased nitrogen retention from the feed.

Abstract: The present invention relates to pharmaceutical presentations for animals which are administered orally and which are accepted readily by the animals (for example dogs, cats and horses), to processes for their preparation and to their use, in particular as endoparasiticides.

Abstract: An enzyme in a dosage form for oral use in mammals is provided, wherein the enzyme has an activity of converting fat in a food material into 1,3-diglyceride and/or 1-monoglyceride. The enzyme has never been used conventionally for oral dosing to mammals. The enzyme in an oral dosage form can effectively decrease the body fat and/or internal fat in mammals in the course of general dietary life.

Abstract: This invention provides for a chewable veterinary formulation, which does not contain animal products, which comprises:

Abstract: Disclosed is a method for moderating the behavior of a dog living in an animal shelter wherein said dog is fed a high quality diet, and wherein said dog is optionally provided periodic interaction with a human.

Abstract: The invention relates to a solid antimicrobial product suitable for the preservation of an organic material and for combating of detrimental microorganisms, as well as for pH control. The product contains, absorbed into a support a concentrated formic acid partly neutralized with gaseous ammonia, the water content of the formic acid being below 2% by weight. In addition, the invention comprises a method for preparing the product.

Abstract: Chromium is an essential element which has been shown to have beneficial effects on carbohydrate and lipid metabolism. Often, dietary intake is suboptimal, and nutritional supplements may not be effective due to poor absorption in the gastrointestinal tract. A novel chromium-histidine complex has been prepared which significantly improves absorption capability over current available chromium nutritional supplements. The complex is safe, easily prepared and may be combined with an ingestible carrier for consumption as a tablet, capsule, aqueous solution, food or food product.

Abstract: Seaweed supplement, e.g., seaweed extract or seaweed meal is directly fed to cattle or pigs in amount of 0.01 to 5% by weight of diet to enhance carcass quality. The enhancement of carcass quality for cattle is manifested by increased quality grade, increased marbling, increased ribeye area and decrease in yield grade in meat obtained on slaughter compared to where seaweed supplement is not fed. The enhancement of carcass quality for swine is manifested by increased marbling, increased firmness and decreased cooler shrink in meat obtained on slaughter compared to where seaweed supplement is not fed.

Abstract: Methods and compositions are described for relieving joint pain and discomfort in a warm-blooded vertebrate by delivering via oral ingestion a nutritional supplement comprising an effective amount of hyaluronic acid, or a salt or digest thereof, and a nutritionally acceptable carrier.

Abstract: A process is provided for limiting weight gain in cats. The process includes feeding the cat a pet food composition that includes a source of protein, a source of fat, and a source of carbohydrates from a grain source that excludes rice. Use of the preferred low glycemic index grain sources that comprise a blend of corn and sorghum; a blend of corn, sorghum, and barley; or a blend of corn, sorghum, and oats, has the effect of decreasing the postprandial blood glucose and insulin response of the cat as compared to when feeding a rice-based diet. The result is that the animal becomes satiated and voluntarily decreases its intake of food, causing less weight gain. This effect is even more marked when the composition is fed to male cats.

Abstract: The present invention relates to a food composition for domestic carnivores which makes it possible to prevent or correct pigmentation abnormalities and/or to improve the quality of the fur of the said domestic carnivores, characterized in that it contains a source of free tyrosine representing at least 5% of the total tyrosine supplied. The invention also relates to a method for preventing or correcting pigmentation abnormalities of the fur of domestic carnivores that uses said food composition.

Abstract: Novel acylglycerides are disclosed comprising mono-, di- and triacylglycerides characterized by predominantly containing the conjugated linoleic acids t9,c11- and c10,t12 octadecadienoic acids to the exclusion of 11,13-, 8,10- and trans,trans isomers.

Abstract: A poultry and livestock feed additive composition containing 36 wt. % electrolytes, roughage and mineral oil to increase their dietary electrolyte balance. Addition of the electrolyte additive composition improves breeder hen performance as to egg production, body weight, and reduced mortality from heat stress. Broiler chickens on this diet result in increased processing yield, feed conversion and body weight. A method of preparing this dietary electrolyte feed for poultry and livestock is also described.

Abstract: Hydrolyzable tannin extracts from plants are provided which have activity to prevent bacterial adherence to surfaces. Methods for prevention and treatment of urinary tract and kidney infections in animals and humans are provided.

Abstract: The instant invention is directed to a protective covering for application on livestock feedstuffs to prevent spoilage of the feedstuffs that is also edible by livestock, and includes a nutritive starch source to provide a nutritive aggregate ingredient, a salt to promote stability in a protective solution, a non-protein nitrogen source to act as a surfactant, and cement to promote spraying application of the protective solution formed from the covering. The instant invention is directed to a protective covering that includes a dry mixture, to which a sufficient amount of water is added to form an aqueous solution. The dry mixture includes a nutritive starch source, a salt source, a non-protein nitrogen source such as urea, and cement. Water is added to the dry mixture, resulting in the instant protective solution. The protective solution is then applied to various target surfaces, which include typical livestock feedstuffs such as silage, hay and grain.

Abstract: A bioactive food complex product, method for preparing a bioactive food complex product and method for controlling disease using probiotics and quorum sensing inhibitors such as inhibitory furanones and other bioactive compounds included in both the continuous and dispersed phases of a bioactive food complex product. The product is comprised of a solids-in-oil or an oil-in-solids emulsion forming a first emulsion that is itself emulsified in polymer forming oil-in-polymer or solids-in-polymer emulsion complex. The bioactive complex is formed of two emulsions with the first emulsion comprising the dispersed phase and a hydrocolloid polymer serving as the continuous phase. The second emulsion complex is then crosslinked to form a physically stable matrix.

Abstract: The present invention includes a method of maintaining rumen health in ruminants. The method includes providing to a ruminant a low-moisture block made of molasses and having a buffer. The low-moisture buffer block is specifically designed such that licking rather than chewing consumes the block. The licking action of the cows increases salivation, which acts as a natural buffer for the maintenance of the overall rumen health.

Abstract: A method for culturing Bacillus subtilis in such a manner that a vitamin K derivative is accumulated in the largest amount in the cells of the microorganism. A method for the culture of Bacillus subtilis, which comprises culturing Bacillus subtilis and recovering the cells of the microorganism before the vitamin K produced within the cells of the microorganism is released from the cells is disclosed, as well as the cultured product of Bacillus subtilis cultured by this method, a water-soluble vitamin K derivative originating in the cultured product, a food product, beverage, or feed containing the cultured product and/or the water-soluble vitamin K derivative, and a method for extracting vitamin K.

Abstract: A method for culturing Bacillus subtilis in such a manner that a vitamin K derivative is accumulated in the largest amount in the cells of the microorganism. A method for the culture of Bacillus subtilis, which comprises culturing Bacillus subtilis and recovering the cells of the microorganism before the vitamin K produced within the cells of the microorganism is released from the cells is disclosed, as well as the cultured product of Bacillus subtilis cultured by this method, a water-soluble vitamin K derivative originating in the cultured product, a food product, beverage, or feed containing the cultured product and/or the water-soluble vitamin K derivative, and a method for extracting vitamin K.

Abstract: The present invention relates to an isolated and purified strain of the species Lactobacillus sanfranciscensis which produces levan. The present invention further relates to a method of producing the levan, and to a method of preparing various human or pet food products or cosmetic products which utilizes the levan and/or a strain producing the same.

Abstract: Disclosed are a multipurpose, high-functional, alkaline solution composition, preparation therefor and use thereof as a nonspecific immunostimulator. The composition comprises 1-25 parts by weight of borax (Na2B4O7.10H2O), 10−5-10−4 parts by weight of sodium thiosulfate (Na2S2O3.5H2O), 30-150 parts by weight of potassium carbonate, 30-200 parts by weight of refined sugar (C12H22O11), and 100-200 parts by weight of water, based on 100 parts by weight of sodium metasilicate (Na2SiO3.5H2O). In addition to bringing about an improvement in disease resistance, weight gain rate, crop yield, crop quality, harvest time, the composition shows nonspecific immunostimulating activities, including antibody production and immune enhancement, by activating immune cells, thereby maximizing vaccination effects on malignant viral diseases.

Abstract: Disclosed are a breeding method of a female pig for propagation characterized by feeding at least one lipid selected from a fatty acid having 12 to 24 carbon atoms which has a melting point falling in a range of −60 to 40° C. and an iodine value falling in a range of 30 to 470 and which has 2 to 6 double bonds in a molecule, a triglyceride containing the above fatty acid and a metal salt of the above fatty acid, and a feed for a female pig for propagation containing the above lipid in a proportion of 0.5 to 10 % by weight in terms of the fatty acid described above.

Abstract: The invention provides a method for treating abnormal glucose metabolism and insulin resistance in an animal by feeding a diet comprising high protein and moderate amounts of carbohydrate and fat. The invention also provides a method for treating conditions associated with insulin resistance or decreased longevity by feeding an animal such diets.

Abstract: Nutritional compositions containing selenium, colostrum and whey are described. The compositions may be mixed with mammalian food to increase the concentration of glutathione in the mammalian body thereby to enhance the response of the mammal's immune system to infection.

Abstract: A pet food, such as a dog food and a cat food, contains a cyclodextrin such as &bgr;-cyclodextrin, for example, a pet food in which the content of fat is equal to or higher than 5% by weight per solid part and the content of &bgr;-cyclodextrin ranges from 1 to 15% by weight per solid part. A method of suppressing an increase in the body weight of a pet or reducing the body weight, is characterized by feeding the pet food to a pet to the extent that the ingested amount of &bgr;-cyclodextrin, per day, ranges from 0.1 to 5 g per 1 kg of body weight. A pet food is suited to a pet's liking because of having the same taste and mouth feel as conventional pet foods, and suppresses an increase in the body weight of a pet or reduces body weight with the same feeding amount as usual, and a method suppresses an increase in the body weight of a pet or reduces body weight without impairing the health of pets.

Abstract: A method for increasing the diet digestibility of food for an animal and modulating the firmness of fecal droppings (or stool index or excreta) of an animal which comprises conditioning an aqueous meat slurry comprising fat and meat (protein) by homogenizing and emulsifying the fat and meat ingredients in water, treating the conditioned slurry with an effective amount of an enzyme composition under conditions of pH and temperature for a time effective to cause hydrolysis resulting in the production of an enhanced digestibility and stool index modulating composition and utilizing this composition as an animal food or incorporating this stool index improving composition into an animal food, in an amount effective to modulate the stool index of animal droppings, and increase the food digestibility.

Abstract: A method for improving body weight gain and increasing feed conversion efficiency of in animals by feeding the animals a diet containing antibodies against anti-nutritional factors in food.

Abstract: A poultry eggshell strengthening composition for enhancing eggshell thickness and external eggshell membrane thickness, containing a viable microorganism of the genus Bacillus as an active ingredient, optionally together with a carrier or diluent.

Abstract: A new and improved formulation and method for making same, for a broad spectrum antimicrobial treatment for bacterial and viral infections in cattle, horses, pigs, sheep and other domestic and non-domestic animals. More particularly, the present invention relates to a treatment which enables rapid relief of symptoms in an affected animal with a mortality of less than 1 percent by providing trace organic minerals in microgram quantities which act as nutrients for the animal. The treatment provides further nutritional requirements in the form of vitamin A, folic acid and vitamin D3 supplements, cobalt amino acid chelates and dried kelp, a source of minerals, amino acids, simple and complex carbohydrates, iodine and fiber. In addition, a bacterial innoculum consisting of Acidophilus species is introduced which would inhibit growth of pathogenic or opportunistic species of bacteria by competition for nutrients as well as providing for required vitamins as a by-product of metabolism.

Abstract: Disclosed are a breeding method of a female pig for propagation characterized by feeding at least one lipid selected from a fatty acid having 12 to 24 carbon atoms which has a melting point falling in a range of −60 to 40° C. and an iodine value falling in a range of 30 to 470 and which has 2 to 6 double bonds in a molecule, a triglyceride containing the above fatty acid and a metal salt of the above fatty acid, and a feed for a female pig for propagation containing the above lipid in a proportion of 0.5 to 10% by weight in terms of the fatty acid described above. According to the breeding method of a female pig for propagation of the present invention, breeding results can be elevated by further increasing a litter size, allowing the number of delactation to grow large, shortening the days of returning estrus and increasing an annual average delivery frequency.

Abstract: The current invention is directed toward a method for inhibiting methanogenesis and/or the growth of methanogens. The method comprises contacting a methanogenic archaea medium with a methane inhibiting amount and/or a growth inhibiting amount of a compound that specifically inhibits methane formation and inhibits the growth of methanogens. A method to increase feed efficiency in a ruminant is also provided via administering to the animal an effective rumen modifying amount of a compound that specifically inhibits methanogenesis.

Abstract: The present invention relates to a preparation for use in animal feed. The preparation comprises sorbic acid and at least one bioavailable &bgr;-glucan and also if appropriate a carrier and a further acid. In addition, the invention relates to the use of the preparation alone in feeds or in a mixture with other feed additives for improving the hygiene state of the feed and for growth promotion in farm animal rearing.

Abstract: The invention concerns a conditioned composition comprising at least a liquid absorbed on a support containing a precipitated silica, said silica being in the form of substantially spherical beads and having: a mean pellet size greater than 150 &mgr;m; a filling density in compact state (DRT) greater than 0.29; an oversize rate for a grid with mesh aperture size of 75 &mgr;m of at least 92% by weight. The invention also concerns the use of such a silica as a support for liquid.

Abstract: Delivery systems and methods are provided for delivering a biologically active protein to a host animal. The systems and methods provided include obtaining an algal cell transformed by an expression vector, the expression vector comprising a nucleotide sequence coding for the biologically active protein, operably linked to a promoter. In one illustrated embodiment, the biologically active protein is an antigenic epitope and upon administration to the animal the algal cell induces an immune response in the host animal.

Abstract: The present invention provides a method for altering the tryptophan content of a plant by introducing and expressing an isolated DNA segment encoding an anthranilate synthase in the cells of the plant. Transgenic plants transformed with an isolated DNA segment encoding an anthranilate synthase, as well as human or animal food, seeds and progeny derived from these plants, are also provided.

Abstract: Provided is a bacteriostatic composition for salmonellae containing, as the active ingredient, a fermented broth obtained by effecting fermentation with the use of a lactic acid bacteriium belonging to the genus Leuconostoc, Streptococcus or Streptobacterium in a sucrose-containing medium, or a preparation originating in the supernatant obtained by subjecting the fermented broth to fractional precipitation from a water-miscible organic solvent.

Abstract: The present invention relates to a method for the production of natural taurine-enriched milk using biological metabolism, in which a precursor for synthesis of taurine is prepared in the shape of a pallet or matrix resistant to degradation in the rumen of ruminants and added to a feedstuff, such that biosynthesis of taurine is induced by stimulation of a substrate. According to the method of the present invention, methionine or methionine precursor which is the precursor for taurine synthesis is coated with additives including an inert material and a filler, and thus protected from a rumen pH and an enzymatic action of rumen microorganisms. As a result, problems of the rumen degradation and the metabolism obstruction can be solved. Taurine-enriched milk according to the present invention contains taurine at a higher concentration than general milk, and hence, can be effectively used for the preparation of functional baby foods, and for the preparation of health foods.