Organic Sulfate Or Sulfonate Containing Patents (Class 424/56)
  • Patent number: 4364927
    Abstract: Compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise condensation polymers of formaldehyde with naphthalene sulfonic acid as well as the pharmaceutically acceptable salts thereof in a pharmaceutically acceptable vehicle, and the periodic application thereof of teeth.
    Type: Grant
    Filed: July 25, 1980
    Date of Patent: December 21, 1982
    Assignee: Johnson & Johnson Products, Inc.
    Inventors: Tibor Sipos, Henry F. Motkowski, Jr.
  • Patent number: 4361547
    Abstract: Compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated aromatic formaldehyde condensation polymers and the pharmaceutically acceptable salts thereof in a pharmaceutically acceptable vehicle, and the periodic application thereof to teeth.
    Type: Grant
    Filed: July 25, 1980
    Date of Patent: November 30, 1982
    Assignee: Johnson & Johnson Products, Inc.
    Inventors: Tibor Sipos, Robert J. Gander, Carl J. Buck
  • Patent number: 4360512
    Abstract: Compositions for preventing the attachment of dental plaque to the surfaces of the teeth comprise certain sulfonated poly(arylene ether sulfone) polymers and the pharmaceutically acceptable salts thereof in a pharmaceutically acceptable nonabrasive gel vehicle comprising a selected polyoxypropylene/polyoxyethylene block copolymer as the principal gelling agent.
    Type: Grant
    Filed: July 25, 1980
    Date of Patent: November 23, 1982
    Assignee: Johnson & Johnson Products Inc.
    Inventor: James D. Vidra
  • Patent number: 4360513
    Abstract: Compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated poly(arylene ether sulfone) polymers and the pharmaceutically acceptable salts thereof in a pharmaceutically acceptable vehicle, and the periodic application thereof to teeth.
    Type: Grant
    Filed: July 25, 1980
    Date of Patent: November 23, 1982
    Assignee: Johnson & Johnson Products, Inc.
    Inventor: Carl J. Buck
  • Patent number: 4360515
    Abstract: Compounds useful in compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated alkoxynaphthalenes and the pharmaceutically acceptable salts thereof. They are used in pharmaceutically acceptable vehicles that are periodically applied to teeth.
    Type: Grant
    Filed: July 25, 1980
    Date of Patent: November 23, 1982
    Assignee: Johnson & Johnson Products, Inc.
    Inventor: Carl J. Buck
  • Patent number: 4360514
    Abstract: Compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain pharmaceutically acceptable salts of sulfonated alkylnaphthalenes. They are used in pharmaceutically acceptable vehicles that are periodically applied to teeth.
    Type: Grant
    Filed: July 25, 1980
    Date of Patent: November 23, 1982
    Assignee: Johnson & Johnson Products Inc.
    Inventor: Carl J. Buck
  • Patent number: 4357313
    Abstract: A toothpaste of improved rheological properties wherein drying and plug formation is reduced or prevented. The toothpaste contains a vehicle in which there is present about 45-85% by weight of liquid phase containing up to about 35% by weight of sorbitol and at least about 25% by weight of water and a solid phase including about 0.5-10% by weight of gelling agent. Drying and plug formation is reduced by including in the liquid phase about 5-20% by weight of polyethylene glycol having an average molecular weight between about 900 and 1600.
    Type: Grant
    Filed: December 22, 1980
    Date of Patent: November 2, 1982
    Assignee: Colgate Palmolive Company
    Inventors: Kenneth Harvey, Stephen T. Connors
  • Patent number: 4350680
    Abstract: A dentifrice comprising an impure insoluble sodium metaphosphate polishing agent is disclosed, the dentifrice using a mixture of anionic phosphates esters as a surface active agent, to reduce or prevent a tendency to cause sloughing or desquamation.
    Type: Grant
    Filed: September 21, 1981
    Date of Patent: September 21, 1982
    Assignee: Colgate-Palmolive Company
    Inventors: Kenneth Harvey, Harry Hayes, Anthony J. Morton
  • Patent number: 4342752
    Abstract: Carbalkoxymethyl derivatives of rutin poly(H-)sulfate and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: June 15, 1981
    Date of Patent: August 3, 1982
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, John F. Poletto, Seymour Bernstein
  • Patent number: 4338346
    Abstract: L-1-hydroxymethyl alkaneamide derivatives of .alpha.-L-aspartic acid have been prepared and have been discovered to be non-nutritive sweeteners having favorable chemical and physiological properties for use in compositions ingested orally.
    Type: Grant
    Filed: August 14, 1980
    Date of Patent: July 6, 1982
    Assignee: The Procter & Gamble Company
    Inventor: Larry M. Brand
  • Patent number: 4337249
    Abstract: N-(4-O-.alpha.-D-glucopyranosyl-.beta.-D-glucopyranosyl)-3,4-dihydroxycinna mamide, nonakis (H-sulfate) (nonaester), nona-alkali metal or alkaline earth metal-salts, useful as modulators of the complement system, the intermediates thereof and the process of making such salts and intermediates.
    Type: Grant
    Filed: August 3, 1981
    Date of Patent: June 29, 1982
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Patent number: 4314991
    Abstract: Polymers useful in compositions and methods for preventing the attachment of dental plaque to the surface of the teeth of mammals comprise certain sulfonated polyamino acids and salts thereof in a pharmaceutically acceptable vehicle and the periodic application thereof to teeth.
    Type: Grant
    Filed: July 25, 1980
    Date of Patent: February 9, 1982
    Assignee: Johnson & Johnson Products Inc.
    Inventor: Tibor Sipos
  • Patent number: 4307077
    Abstract: Compounds useful in compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated bis(naphthoxy)alkanes and the pharmaceutically acceptable salts thereof. They are used in pharmaceutically acceptable vehicles that are periodically applied to teeth.
    Type: Grant
    Filed: July 25, 1980
    Date of Patent: December 22, 1981
    Assignee: Johnson & Johnson Products Inc.
    Inventor: Carl J. Buck
  • Patent number: 4307078
    Abstract: Compounds useful in compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals comprise certain sulfonated bis(alkylphenoxy)alkanes and the pharmaceutically acceptable salts thereof. They are used in pharmaceutically acceptable vehicles that are periodically applied to teeth.
    Type: Grant
    Filed: July 25, 1980
    Date of Patent: December 22, 1981
    Assignee: Johnson & Johnson Products Inc.
    Inventor: Carl J. Buck
  • Patent number: 4301143
    Abstract: Dental cream having a smooth texture with little tendency to form grain containing calcium carbonate polishing agent and sodium lauryl sulphate surface active agent having a broad distribution of alkyl groups containing 10-18 carbon atoms and as additive which reduces grain and alkali metal pyrophosphate or an anionic phosphate mono- and di-ester mixture.
    Type: Grant
    Filed: November 20, 1980
    Date of Patent: November 17, 1981
    Assignee: Colgate-Palmolive Company
    Inventor: Giacinto G. Barberio
  • Patent number: 4264580
    Abstract: Dental cream having a smooth texture with little tendency to form grain containing calcium carbonate polishing agent and sodium lauryl sulphate surface active agent having a broad distribution of alkyl groups containing 10-18 carbon atoms and as additive which reduces grain an alkali metal pyrophosphate or an anionic phosphate mono- and di-ester mixture.
    Type: Grant
    Filed: December 17, 1979
    Date of Patent: April 28, 1981
    Inventor: Giacinto G. Barberio
  • Patent number: 4256730
    Abstract: Oral compositions which contain as a sweetening agent 6-methyloxathiazinone dioxide or an alkali metal or alkaline earth salt thereof in an amount of from about 0.05% to about 0.80%.
    Type: Grant
    Filed: August 24, 1978
    Date of Patent: March 17, 1981
    Assignee: The Procter & Gamble Company
    Inventor: James J. Benedict
  • Patent number: 4251507
    Abstract: The present invention relates to an improved method for cleansing of human teeth to help reduce and control dental plaque as an aid in preventing dental caries and periodontal disease. In particular, it relates to a viscous composition of particular characteristics and a process for application thereof to accomplish these objectives.
    Type: Grant
    Filed: October 2, 1979
    Date of Patent: February 17, 1981
    Assignee: Dominion Pharmacal, Inc.
    Inventor: B. Newell Olson
  • Patent number: 4238476
    Abstract: A clear gel dentifrice containing "narrow cut" alkali metal lauryl sulphate in which the C.sub.12 content is at least 90% by weight of the total alkyl content and a fluorine providing compound. The dentifrice contains a further anionic surface active agent which is a substantially saturated higher aliphatic acyl amide of a lower aliphatic amino carboxylic acid salt, a substantially saturated higher fatty aliphatic alcohol alkylene oxide sulphate or a mixture of mono- and di- phosphate esters.
    Type: Grant
    Filed: May 10, 1979
    Date of Patent: December 9, 1980
    Assignee: Colgate Palmolive Company
    Inventor: Kenneth Harvey
  • Patent number: 4223003
    Abstract: A dentrifice in paste or powder form which contains, in addition to the usual constituents, at least one physiologically compatible, natural or synthetic dye and at least one high-foam surfactant and in which the dye and surfactant contents are so co-ordinated that colored foam produced by the user on brushing takes 20 seconds or more to become white or only pale in color so that this serves as an indication of the correct period of brushing necessary.
    Type: Grant
    Filed: April 20, 1979
    Date of Patent: September 16, 1980
    Assignee: Wurttembergische Parfumerie-Fabrik GmbH
    Inventor: Hans-Ulrich Scheller
  • Patent number: 4209504
    Abstract: A toothpaste composition contains an alkali metal aluminum silicate zeolite as the polishing agent base. The composition is non-corrosive to aluminum containers, polishes well without excessive abrasion and is compatible with dental fluorine compounds. A particularly suitable polishing agent is Zeolite A having the empirical formula Na.sub.12 (AlO.sub.2).sub.12.(SiO.sub.2).sub.12.27H.sub.2 O.
    Type: Grant
    Filed: December 20, 1978
    Date of Patent: June 24, 1980
    Assignee: Blendax-Werke R. Schneider GmbH & Co.
    Inventors: Helmut Harth, Dieter Becker
  • Patent number: 4177258
    Abstract: A dentifrice useful for remineralizing subsurface carious lesions of dental enamel which contains sources of calcium ions and phosphate ions as well as fluoride ions and further includes as agent to stabilize against precipitation of the calcium and phosphate ions, an antinucleating agent such as ethylenediamine tetramethylenephosphonic acid or water soluble salt thereof, the pH of the dentifrice being about 5-9, preferably close to physiological conditions, such as about 6.8-7.5.
    Type: Grant
    Filed: March 14, 1979
    Date of Patent: December 4, 1979
    Assignee: Colgate Palmolive Company
    Inventors: Maria C. S. Gaffar, Abdul Gaffar
  • Patent number: 4170634
    Abstract: Dentifrice possessing superior cleaning and polishing characteristics containing as the essential ingredients at least one hard abrasive in an amount to provide a radioactive enamel abrasion to the dentifrice of above about 400, such as calcined alumina, zirconium silicate, and the like, and a non-toxic zinc compound in an amount to provide at least about 0.0065% by weight of zinc to the dentifrice.
    Type: Grant
    Filed: January 17, 1977
    Date of Patent: October 9, 1979
    Assignee: Colgate Palmolive Company
    Inventors: Martin Cordon, James Norfleet
  • Patent number: 4170633
    Abstract: This invention discloses compositions effective in inhibiting or reducing plaque in the oral cavity. Chewing gums are a preferred vehicle for delivering the plaque inhibiting benefit of the present invention.
    Type: Grant
    Filed: November 28, 1977
    Date of Patent: October 9, 1979
    Assignee: General Mills, Inc.
    Inventors: Austin C. Wagenknecht, deceased, George V. Daravingas, William E. Koski
  • Patent number: 4152420
    Abstract: An oral composition effective to promote oral hygiene containing as an anticalculus agent a water soluble oligomer of the formula ##STR1## wherein M is a water soluble orally acceptable cation;R.sub.1, r.sub.2, r.sub.3 and R.sub.4 are independently H, methyl or ethyl;Y is at least one hydrophilic member of the group consisting of --COOM.sub.1, --CONH.sub.2, and --CH.sub.2 OH:X is at least one hydrophobic member of the group consisting of --CN, --COOR, --COOR.sub.5 OR, --CONHR, --COONHR.sub.5 COR, and --OOCR;M.sub.1 is H or M;R is C.sub.1-8 alkyl;R.sub.5 is C.sub.1-4 alkylene;A is 0-7; andA+b is about 4-15.
    Type: Grant
    Filed: July 28, 1978
    Date of Patent: May 1, 1979
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Stuart D. Friedman
  • Patent number: 4150112
    Abstract: This invention discloses compositions effective in inhibiting or reducing plaque in the oral cavity. Chewing gums are a preferred vehicle for delivering the plaque inhibiting benefit of the present invention.
    Type: Grant
    Filed: November 28, 1977
    Date of Patent: April 17, 1979
    Assignee: General Mills, Inc.
    Inventors: Austin C. Wagenknecht, deceased, George V. Daravingas, William E. Koski
  • Patent number: 4150151
    Abstract: A physiologically acceptable, germicide free antibacterial liquid mouthwash and methods for its use is disclosed. The mouthwash comprises water, ethanol, an essential oil flavor mixture and about 0.1 to about 0.6 percent of an alkyl sulfate anionic surfactant mixture of C.sub.12 and C.sub.14 sulfates wherein the ratio of C.sub.12 to C.sub.14 alkyl sulfates is in the range of about 75:1 to about 1:1. Additional ingredients which may be incorporated within specific ranges include nonionic emulsifiers, humectants, alkali metal halides, buffering salts, sweetening agents and colorants.
    Type: Grant
    Filed: December 12, 1977
    Date of Patent: April 17, 1979
    Assignee: Lever Brothers Company
    Inventors: Morton Pader, Craig T. Elton
  • Patent number: 4138477
    Abstract: A novel composition to prevent and control mouth odor, which is also effective in preventing calculus, plaque, caries and periodontal disease containing as the essential agent, a zinc-polymer combination formed by the reaction or interaction of a zinc compound with an anionic polymer containing carboxylic, sulfonic and/or phosphonic acid radicals.
    Type: Grant
    Filed: May 28, 1976
    Date of Patent: February 6, 1979
    Assignee: Colgate Palmolive Company
    Inventor: Maria Corazon S. Gaffar
  • Patent number: 4130636
    Abstract: There is disclosed an oral product containing a new and improved surfactant system that is non-toxic, edible and surprising substantially tasteless.
    Type: Grant
    Filed: July 27, 1977
    Date of Patent: December 19, 1978
    Assignee: Colgate-Palmolive Company
    Inventor: Kenneth Tomlinson
  • Patent number: 4123527
    Abstract: Novel N-tricyclic derivatives of azetidine are disclosed of the general formula ##STR1## where A is a C.sub.1 -C.sub.3 alkylene group, a C.sub.2 -C.sub.3 alkenylene group or a cyclopropylene group, the remaining substituents being defined in the specification. Such compounds are useful for their anti-depressant, anti-convulsant and anxiolytic activities. The compound 1-[5-(10, 11-dihydro-5H-dibenzo [a,d]cyclopheptenyl)]-3-methyl-amino-azetidine is illustrative.
    Type: Grant
    Filed: January 9, 1976
    Date of Patent: October 31, 1978
    Assignee: Carlo Erba, S.p.A.
    Inventors: Piero Melloni, Arturo Della Torre, Francesco Lauria, Norina Passerini, Alessandro Rossi, Raffaele Tommasini
  • Patent number: 4105758
    Abstract: Oral compositions containing an anticalculus agent selected from the group consisting of compounds having the following structural formulas: ##STR1## wherein X, X', Y, and Y' are selected from the group consisting of H, OH, SO.sub.3 Na, and CH.sub.2 N(CH.sub.2 COOH).sub.2 and additionally wherein at least two of the substituents X, X', Y, and Y' must be hydroxyls, and at least one of the further of said substituents must be OH, SO.sub.3 Na, or CH.sub.2 N (CH.sub.2 COOH).sub.2. The preferred anthraquinoid derivatives are Alizarin red S monohydrate, Alizarin complexone dihydrate, purpurin, and purpurin sulfonate.
    Type: Grant
    Filed: December 27, 1976
    Date of Patent: August 8, 1978
    Assignee: Colgate-Palmolive Company
    Inventor: Ronald S. Schreiber
  • Patent number: 4070449
    Abstract: Compositions are disclosed having a physiological cooling action on the skin. The compositions contain as the active ingredient certain acyclic secondary and tertiary sulphoxides and sulphones.
    Type: Grant
    Filed: July 20, 1973
    Date of Patent: January 24, 1978
    Assignee: Wilkinson Sword Limited
    Inventors: David G. Rowsell, Roger Hems
  • Patent number: 4039655
    Abstract: The addition of organo germanium compounds having the formulaR.sub.3 GeX or (R.sub.3 Ge).sub.2 Ywherein R is an aliphatic or cycloaliphatic hydrocarbon group and X is an anion, such as carboxylate, sulphonate, halogen or hydroxyl, and Y is oxygen, sulphur, or sulphate, to conventional agents used in oral hygiene will significantly reduce the formation of plaque on teeth and thus reduce the incidence of caries. The preferred germanium compounds are the tri-n-butyl and tri-n-pentyl. The fluoride ion is the preferred anion because of its known anti-caries properties.
    Type: Grant
    Filed: June 5, 1975
    Date of Patent: August 2, 1977
    Inventors: Gerrit J. M. van der Kerk, Antje Kaars Sijpesteijn, Eric J. Bulten
  • Patent number: 4029759
    Abstract: Compositions, particularly edible compositions, oral compositions and flavor compositions, containing a compound imparting a cooling sensation, said compound being a hydroxymethyl or hydroxyethyl derivative of para-menthane, for example 2-hydroxymethylmenthol.
    Type: Grant
    Filed: February 15, 1973
    Date of Patent: June 14, 1977
    Assignee: Lever Brothers Company
    Inventors: Francoise Ernestine Lucie Humbert, Yves Tollard D'Audiffret
  • Patent number: 3963832
    Abstract: A liquid or pasty putrefaction resistant thixotropic gel dentifrice that is stable against phase separation of solid abrasive dentifrice particle ingredients which consists of 0.3 to 2% by weight of a polysaccharide having a number average molecular weight of not less than 100,000 and the molecule of said polysaccharide containing D-glucose, D-mannose, D-galactose and D-glucuronic acid in the molar ratio of about 3:3:1:2.
    Type: Grant
    Filed: July 24, 1975
    Date of Patent: June 15, 1976
    Assignees: Teijin Limited, Sunstar Dentifrice Co., Ltd.
    Inventors: Shigeru Hashimoto, Eizi Ninomiya, Junko Kuroda
  • Patent number: 3962417
    Abstract: An effervescent dentifrice in chewable tablet form particularly effective in controlling Bacillus Acidophilios comprising a compressed homogenous mixture of an acid neutralizer, a cariespreventative, an acid, a wetting agent, and flavoring and sweetening agents. Upon crushing the dentifrice tablet in the mouth, a pleasant-tasting, effective microbicide is released.
    Type: Grant
    Filed: March 27, 1974
    Date of Patent: June 8, 1976
    Inventor: Charles J. Howell
  • Patent number: 3954962
    Abstract: An essentially non-aqueous oral hygiene product is disclosed comprising an alcohol base, a combination of viscosity adjusters, e.g., polyvinylpyrrolidone and glycerin; a detergent such as sodium lauryl sulfate; a sweetening agent such as saccharin, and a flavor additive. The combination of viscosity adjusters imparts a suitable viscosity and body to the product to enable it to adhere to a toothbrush and be readily dispersible in water to be used as a mouthwash.
    Type: Grant
    Filed: April 1, 1974
    Date of Patent: May 4, 1976
    Assignees: Alan R. Tripp, Samuel Grubstein, Eugene F. Whelan, E. R. Finnis, Samuel Prussin
    Inventor: Samuel B. Prussin
  • Patent number: 3942512
    Abstract: A mouthwash solution and method for treating both the lower and upper throat. The aqueous solution contains dioctyl sodium sulfosuccinate as the active ingredient. The treatment of the lower throat involves holding a small amount of the solution in the mouth for a short period of time. The treatment for the upper throat area is to hold a small amount of the solution in the mouth, lie down with the head back, swallow several times, and hold the head in position for a short period of time.
    Type: Grant
    Filed: February 12, 1975
    Date of Patent: March 9, 1976
    Inventor: Edgar R. Hargett
  • Patent number: 3939261
    Abstract: There is disclosed a substantially anhydrous dentifrice which contains a dipeptide sweetener in combination with an acid anhydride. There is also disclosed a method of making the same.
    Type: Grant
    Filed: August 30, 1974
    Date of Patent: February 17, 1976
    Assignee: Colgate-Palmolive Company
    Inventor: Jordan B. Barth
  • Patent number: 3935307
    Abstract: A liquid or pasty dentifrice comprising, uniformly incorporated therein, a polysaccharide as a thickening and suspending agent, said polysaccharide having a number average molecular weight (Mn) of not less than 100,000 and the molecule of said polysaccharide containing D-glucose, D-mannose, D-galactose and succinic acid in the approximate molar ratio of 1 : 0.03 : 0.1 : 0.2. The polysaccharide is obtained by cultivating Alcaligenes faecalis var. myxogenes in a culture medium containing at least one member selected from the group consisting of lactic acid, pyruvic acid, succinic acid, fumaric acid, malic acid and esters thereof and saccharide.
    Type: Grant
    Filed: May 30, 1974
    Date of Patent: January 27, 1976
    Assignees: Teijin Limited, Sunstor Dentrificy Co. Ltd.
    Inventors: Kenji Aimoto, Shigeru Hashimoto, Toyoaki Yoneda