Abstract: A method using an alkaline sodium silicate composition to inhibit the toxic effects of venom and treat venomous bites and stings.

Abstract: Aspects for utilizing a seawater fluid to optimize egg-production characteristics are disclosed. In one aspect, a method is provided, which includes identifying a desired optimization, determining a corresponding seawater to non-seawater ratio, and generating a seawater fluid according to the ratio. An egg-cultivation method is also provided, which includes ascertaining a desired optimization, selecting a corresponding seawater to non-seawater ratio, and providing a seawater fluid comprising the ratio to a hen. In another egg-cultivation method, hens are provided with a mixed feed comprising a feed to seawater-mineralized produce ratio selected according to a desired optimization. A method to grow produce is also provided, which includes mineralizing soil with a seawater fluid comprising a seawater to non-seawater ratio corresponding to a preferred optimization.

Abstract: This invention relates to an improved chlorine dioxide solution or liquid mixture containing a phosphate and, as well, as to a composition for forming the chlorine dioxide and phosphate liquid mixture. This improved chlorine dioxide solution is used to clean and/or sanitize without causing corrosion. The corrosion nature of the chlorine dioxide solution is lessened due to the addition of phosphate to the composition.

Abstract: The present invention relates to a method for maintaining normoglycemia in a mammal in need thereof, preferably a critically ill patient suffering from acute stress, and to a method for preventing or limiting renal ischemia-reperfusion (I/R) in a mammal, preferably in a critically ill patient suffering from acute stress.

Abstract: A produce wash is provided that reduces or eliminates the chlorine used in treating produce and inhibits the growth of microorganisms, including bacteria and mold, on pre-harvest and post-harvest produce and extends the shelf-life of the treated produce. Methods of making and using the produce wash also are provided.

Abstract: A single step milling and surface coating process allows for production of a stable dispersion of surface coated nanoparticles in an efficient manner. The process comprises providing feed particles, providing a coating agent, and generating the stable dispersion of surface coated nanoparticles by milling the feed particles in an aqueous medium containing the coating agent such that the coating agent bonds to surfaces of the feed particles as the feed particles are milled to an average particle size of less than about 100 nm.

Abstract: A method for treating or preventing a disease, condition or state in a subject in need thereof by administering to the subject an effective amount of the (?)-enantiomer of perhexyline or a pharmaceutically acceptable salt, prodrug or derivative thereof, substantially free of the (+)-enantiomer, or pharmaceutical composition containing same. The disease, condition or state may be associated with altered tissue energetics, impaired tissue energetics, altered cardiac tissue energetics, impaired cardiac tissue energetics, altered hepatic tissue energetics, impaired hepatic tissue energetics, and diabetes.

Abstract: Provided herein formulations of capsaicin for delivery by nasal route and methods of using the formulations for the treatment of migraines and other severe headaches. The formulations described herein contain mucoadhesives to optimize the therapeutic effect of capsaicin by intranasal delivery.

Abstract: The invention relates to the finding that very favorable pharmacokinetic characters are obtained by combining two strontium salts in one pharmaceutical composition. The present invention relates in one aspect to a pharmaceutical composition comprising at least two strontium salts for use as a medicament, and in particular for the treatment and prevention of bone disorders such as osteoporosis. The composition preferably comprises strontium carbonate and strontium chlorides. Further included may be a vitamin D compound, preferably vitamin D3.

Abstract: Technologies are described herein for styptic compounds comprising a hemostatic or styptic agent suspended within a hydrophobic carrier medium. Example carrier mediums may include waxes, lipids, oils, or combinations thereof. The compound may be a semisolid at room temperature and soft enough to be easily dispensed and formed into or onto bleeding tissue of an animal or human. The hydrophobic qualities of the carrier medium can protect the styptic agent from absorbing moisture. The carrier medium can mechanically support positioning treatments adjacent to the bleeding tissue. The carrier medium can further serve to mechanically seal the tissue to aid in hemostasis while also protecting the tissue from debris and contamination. The carrier medium can aid in maintaining moisture within the tissue. Slurry-based manufacturing processes can support a substantially homogeneous dispersal of styptic agent throughout the carrier medium.

Abstract: Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include ?-hydroxyisocaproic acid and citrulline. The composition may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, ?-keto-glutarate, eicosapentaenoic acid, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.

Abstract: A topical formulation for application to exposed body tissue, the formulation comprising a silver(II) oxide and zinc oxide, intimately dispersed within a carrier medium.

Abstract: The present invention relates to methods of treating cancer through stasis induction, wherein said stasis-inducing treatment results in reduced blood flow to the cells of said cancer, leading to diminished tumor growth and/or tumor death. In one embodiment, the stasis-inducing treatment comprises administering a therapeutically effective amount of a chalcogenide, salt, or prodrug thereof. The method of treating cancer may optionally comprise an additional step of withdrawing a portion of blood from said patient, such that blood flow to said cancer is further reduced or eliminated. In additional embodiments, the method of treating cancer may optionally comprise an additional step of diverting a portion of the blood flow in said patient, such that blood flow to said cancer is further reduced or eliminated.

Abstract: Nutritional compositions having dietary nucleotides, ?-3 fatty acids and citrulline are provided. The nutritional compositions may be formulated to improve T cell function, increase arginine availability in vivo, regulate myeloid-derived suppressor cells (“MDSC”), and decrease the risk and/or severity of infection after surgery or trauma. Methods of making, using and administering such nutritional compositions to individuals in need of same are also provided. Methods for modulating the affects of MDSC's are also provided.

Abstract: The present invention present a novel and cost-effective family of cosmetic compositions comprising inter alia small magnetic particles characterized by magnetic field adapted to be topically administrated adjacent to skin surface, absorbed to epidermal upper skin layers and place in a direct contact to the body, usually above pain suffering regions. The present invention also provides the use of the compositions, especially of nano-powders of salts obtained from the Dead Sea, as an external layer of bandages, dressings, compresses or warps, so constantly approached to be in an intimate contact with the patient's skin.

Abstract: Compositions and methods of phytoparasitic pest population control are provided, the compositions comprise a first component comprising an agriculturally acceptable complex mixture of dissolved organic material characterized by natural organic matter that is of defined composition, suitable for soil, foliar, and seed coating. In one embodiment, the phytoparasitic pest is nematodes.

Abstract: The problem of the present invention is to provide a method or the like for producing reduced water (hydrogen-enriched water), which is effective for various diseases caused by active oxygen, more efficiently than the conventional methods, by putting metallic magnesium or the like in water. Adding a metal such as magnesium, together with a solid phase contained in an anode of an oxidation-reduction reaction, to water increases the saturating amount of magnesium ions, and improves deterioration due to magnesium hydroxide being precipitated on the surface of the metallic magnesium. Thus, the abovementioned problem is solved.

Abstract: An improved beverage can includes a GRAS antimicrobial wipe contained in a low profile pouch that is adhered to the side of the can. The low profile pouch is constructed of a substantially planar substrate that retains the wipe directly to the exterior surface of the can. The pouch includes a perforated tab that is removed to access the wipe. To use, the perforated tab is ripped off, the user reaches into the pouch and pulls out the antimicrobial wipe, and wipes the can as desired, typically focusing on the drinking region of the can.

Abstract: A combination treatment, wherein a strontium-containing compound together with one or more active substances capable of reducing the incidence of bone fracture and/or increasing bone density and/or improving healing of fractured bone and/or improving bone quality are administered for use in the treatment and/or prophylaxis of cartilage and/or bone conditions.

Abstract: This invention relates generally to formulations and methods for improving level of moisture absorption and retention by the skin and for improving the appearance, feel, or comfort of the skin, wherein the formulations comprise pure rainwater. In another embodiment of the invention, the formulations comprise a combination of natural extracts. The present invention is a formulation made substantially without the use of synthetic chemicals and petroleum by-products, wherein the formulation is used for personal care. More specifically, the present invention is a skin care product formulation wherein 90% or more of the ingredients are natural products.

Abstract: A mixing device includes a mixing section that mixes a liquid-phase fluid with one kind or two or more kinds among a solid, a gas, and a liquid-phase fluid different from the above-mentioned liquid-phase fluid, in which the mixing section includes a supply hole for a fluid, a discharge hole for the fluid, a flow path that makes the supply hole and the discharge hole communicate with each other, and a plurality of pins that protrudes from the flow path, and a fluid that includes materials to be mixed is supplied from the supply hole to the flow path, mixed by passing through the flow path with the contact with the pins, and discharged from the discharge hole.

Abstract: An ozone delivery system, method, and apparatus are disclosed. Ozonated water can be used to disinfect and clean various surfaces, equipment, and animals in a dairy setting. Animals can be disinfected and protected from disease through the use of wash-pen and sprayer injections, and other footbath products. Ozone can be educted into a drop hose and a pre-dip line at periodic intervals and into a foot bath to provide refreshed ozonated water. The ozone delivery system and method sterilizes all equipment and floor surfaces without damaging diary equipment components. The system can incorporate computer-controlled options such as maintaining off gas levels, maintaining cleaning and disinfecting records, monitoring ozonated water levels, monitoring concentrations of ozone in said ozonated water, controlling entry and exit gates, controlling a drainage system, and monitoring and educting ozone in a foot bath and wash pen.

Abstract: The present invention relates to the use of deuterium oxide (D2O) for prevention and/or treatment of virus-based diseases of the skin, in particular herpes virus-based and verrucal virus-based diseases of the skin.

Abstract: A method for producing a purified, stable, compressible gas from an aqueous fluid.

Abstract: Chakra stones or crystals are included as part of a personal hygiene or body cleansing composition as a novelty item or for aesthetic or decorative purposes. The chakra stones or crystals can also be used for their spiritual significance and for realigning, revitalizing, or balancing unbalanced chakra energies of the body.

Abstract: A therapeutic method and associated composition for counteracting the negative and toxic physiological effects of the consumption or production of oxygen-modified toxins, such as alcohol, congeners, and associated metabolites, by augmenting or restoring the liver's ability to metabolize said elements, thereby preventing or abating the negative effects of the toxins, such as the symptoms of a hangover in the case of alcohol. Oxygen-infused water with a high solubilization level combined with caffeine, sodium, potassium, dextrose, or flavoring elements provides a therapeutic and pleasant dose before, during, or after the intake of alcohol, thereby increasing the metabolism of oxygen-modified toxin, alcohol, congener, and associated metabolites, replenishing nutrient levels deteriorated by toxin-introduction or alcohol consumption, and treating hangover symptoms.

Abstract: An anti-hypothermia composition is provided, in particular an anti-hypothermia composition that prevents hypothermia caused by general anesthesia during surgical operations. The composition prevents hypothermia by preventing the decrease in the biological function of patients and correcting acidosis. Specifically, the anti-hypothermia composition is a preparation containing a bicarbonate ion and provided in the form of an infusion fluid. The infusion fluid preferably contains sodium bicarbonate as a major component that serves as a source of the bicarbonate ion, along with each or a combination of other electrolytes, glucose and amino acids.

Abstract: The present invention provides compositions comprising silicon and at least one other joint health ingredient such as glucosamine, chondroitin, hyaluronic acid, collage, etc. as well as methods for making and using the same.

Abstract: The present invention relates to methods and compositions for the modulation of wound healing and/or the production of extracellular membrane components by modulating the activity and/or amount of secreted protein acidic and rich in cysteine (SPARC) protein. The invention further provides methods for identifying compounds useful in the above-mentioned methods and compositions.

Abstract: A method for treating myocardial or skeletal muscle anoxia which occurs in coronary or post-infarct disorders or during prolonged physical activity and muscle fatigue. This method comprises the administration of a combination composition comprising (a) an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine, propionyl L-carnitine or the pharmacologically acceptable salts thereof or mixtures thereof; and (b) ribose or a phosphate derivative thereof.

Abstract: A process for producing aqueous chlorous acid solution in which chlorous acid, which is safe for the human body, is easy to handle, and less generates chlorine dioxide, is yielded and used as a disinfectant for a pretreatment in food processing. To an aqueous sodium chlorate solution is added sulfuric acid or an aqueous solution thereof in such an amount and concentration that the pH of the aqueous solution can be kept at 2.3-3.4 to thereby react them and generate chloric acid. Subsequently, hydrogen peroxide is added to the chloric acid in an amount which is equal to or larger than the amount necessary for a reduction reaction to thereby yield chlorous acid. Any one of inorganic acids, inorganic acid salts, organic acids, and organic acid salts, or two or more thereof, or a combination or these is added to the aqueous solution containing chlorous acid yielded, whereby the chlorous and acid can be present for long and the pH of the aqueous solution is regulated to regulated to 3.2-7.0.

Abstract: The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below.

Abstract: A method for activating hydrogen molecules dissolved in water and stabilizing the concentration of the hydrogen molecules is provided. The method for activating and stabilizing hydrogen molecules dissolved in water is characterized by allowing hydrogen ions to coexist with the hydrogen molecules.

Abstract: The present invention relates to hydronium stabilized silicic acid nanoparticles, to the formulation obtained from the said diluted suspension, to the powder obtained from the said dehydrated suspension and to the preparation or dosage form obtained from the said suspension, formulation or powder, to their preparation and their use in all kinds of applications in the domains of food, medicine, pharmaceutics, cosmetics. The present invention provides a stable suspension of colloidal silicic acid nanoparticles having a pH lower than 0.9, a molar silicon concentration between 0.035 and 0.65, a free water concentration of at least 30% (w/v) and a ratio between hydronium ion and Si molar concentrations higher than 2 and preferably inferior to 4.

Abstract: Compositions are provided which stimulate bone growth. Also provided are methods for utilizing the compositions for filling in bone defects, promoting rapid fusion of bone fractures, grafts, and bone-prostheses, and promoting strengthening of osteoporotic bones.

Abstract: Antimicrobial chemical compositions comprise an aluminum phosphate (AlP) solid dispersed within a binding polymer, wherein one or more bioactive materials are disposed within AlP forming a bioactive-AlP complex. The complex may comprise the bioactive material chemically bonded with the AlP, physically combined with the AlP, or a combination of both. The complex may be formed according to precipitation, condensation and sol-gel methods of forming. The complex is engineered to provide a controlled delivery of the bioactive material or a constituent thereof upon exposure to moisture to give a desired level of antimicrobial resistance to a film or composite formed from the composition of at least about 30 ?g/m2, and may also provide a desired degree of corrosion resistance through the release of passivating phosphate anion.

Abstract: Disclosed are oral rehydration compositions with sucrose, sodium, chloride, and citric acid or citrate. The composition further comprises an osmolarity of below 250 mOsm/L, and sodium below 75 meq/L. Further disclosed are methods of treatment using the same.

Abstract: The invention relates to the use of a composition comprising a vitamin, a metal ion, and a surfactant, as a therapeutic agent or disinfectant. The composition has been known as a decontaminant because the same efficiently decomposes DNA. It has now been possible to demonstrate that the agent has surprisingly good compatibility while having a wide-ranging disinfecting effect and is therefore also suitable for other purposes, e.g., for disinfecting or dressing wounds.

Abstract: Methods for treating bacterial respiratory tract infections in an individual comprise administering a therapeutic amount of nitrite composition having a pH of less than 7, and in specific embodiments, a pH of about 5.5-6.5, to the individual. The individual may be a pulmonary disease diagnosed individual and/or the infection may be at least in part caused by mucoid mucA mutant Pseudomonas aeruginosa.

Abstract: The present invention relates to active and intelligent additives having hybrid characteristics, that are compatible with polymers, are thermally and mechanically stable, are capable of releasing electrons and/or photons in the presence of chemical compounds, specifically amino compounds, amide compounds, oxygen reducing compounds, water or vapors thereof. The active and intelligent additives incorporate themselves into polymer matrices allowing the obtainment of active and intelligent polymeric articles. These active and intelligent polymeric articles may act as inhibitors of growth of microorganisms and fungi, as well as indicators of the presence of gasses, either in the atmosphere or caused by the decomposition of foodstuffs, for example.

Abstract: A method of treating and protecting a subject from endotoxin shock by administering a composition including hydrogen, releasing hydrogen in the subject, and down-regulating production of TNF-? and IL-6. A method of treating inflammation in a subject. A method of suppressing hydroxyl radical in a subject. A method of treating inflammation in a subject. A method of reducing the basal level of phosphorylation of MAPKs in non-stimulated monocyte lineage cells in a subject. Methods of performing drug screen tests for compounds that can treat the above conditions. A diagnostic method for diagnosing patients with diseases caused by the MAPK pathway.

Abstract: A scaffold for implantation into a mammal to facilitate vessel growth in repair, regeneration, and/or proliferation of bodily tissue, where the scaffold is based on a borate, silicate, or phosphate, glass-former and is biodegradable upon implantation in mammals. The scaffold includes one or more trace elements from the group consisting of Cu, F, Fe, Mn, Mo, Ni, Si, Sr, and Zn which are released into the host to support vessel growth. A method involves implantation of such scaffolds.

Abstract: A combination biocide (Glutaraldehyde or OPA), quaternary phosphonium biocide (preferably TTPC), alcohol (preferably isopropyl alcohol), and functional excipients for the oil and gas recovery industry. The functional excipients for the oil and gas recovery industry are a cellulose type proppant, a poloxamer wetting agent, a friction-reducing pluronic block copolymer, a drag reducing agent such as polyethylene oxide, and a flocculating agent. The OPA may be of the dialdehyde C6H4(CHO)2 form, and the Glutaraldehyde of formula C5H8O2. Both will produce an inherent bacteriostatic effect and lower surface tension and thus aids in the spread of the TTPC on the biofilm covered surface where it is readily absorbed by the negative surfaces of proteins and bacteria. It thus serves as a binding agent between the TTPC and the application surface. The foregoing constituents are combined in preferred concentrations within acceptable ranges to provide a synergistic biological chemical complementarity system.

Abstract: A composition for a broad-spectrum antiviral agent with excellent preservation stability, which comprises a pure chlorine dioxide solution comprising a chlorine dioxide gas dissolved therein, a chlorite, and a pH adjuster.

Abstract: The invention provides a screening method for identifying an insect-specific TRPA1 modulator by comparing modulation of an insect TRPA1 and a mammalian TRPA1. The invention further provides method of insect control by applying to an insect a insect-specific TRPA1 modulator identified by the screening method.

Abstract: A method for treating myocardial or skeletal muscle anoxia which occurs in coronary or post-infarct disorders or during prolonged physical activity and muscle fatigue. This method comprises the administration of a combination composition comprising (a) an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine, propionyl L-carnitine or the pharmacologically acceptable salts thereof or mixtures thereof; and (b) ribose or a phosphate derivative thereof.

Abstract: The methods for treatment using an adsorbent having a high adsorbability, and capable of adsorbing a large amount of toxins during a retention period in an intestine, and of remarkably increasing an adsorption amount of compounds having a large molecular weight.

Abstract: The invention generally relates to compositions of hypochlorous acid (HOCl) and methods of manufacture thereof. In certain aspects, the invention provides air-free compositions of HOCl. In other aspects, the invention provides methods of making HOCl that involve mixing together in water in an air-free environment, a compound that generates a proton (H+) in water and a compound that generates a hypochlorite anion (OCl?) in water to thereby produce air-free hypochlorous acid.

Abstract: Lightweight, small, portable devices and methods are disclosed that provide oxygen-enriched air using an ultra rapid adsorption cycle based on advanced molecular sieve materials.

Abstract: Methods, kits, cartridges and compounds related to generating chlorine dioxide by exposing ClO2? to at least one of a manganese porphyrin catalyst or a manganese porphyrazine catalyst are described.