Sodium Containing Or Fluorine Containing Patents (Class 424/606)
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Patent number: 7332184Abstract: A colonic cleansing kit comprises an osmotic colonic evacuant, and an oral rehydration mixture. The oral rehydration mixture comprises sugar, and salt. The sugar comprises a glucose containing saccharide, and the salt comprises sodium.Type: GrantFiled: March 28, 2003Date of Patent: February 19, 2008Assignee: Queen's University at KingstonInventors: Stephen J. Vanner, William T. Depew, Robert L. Barclay
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Patent number: 7323452Abstract: A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as catalysts or “pseudo” enzymes for the oxidation. These additives include multivalent transition metal ions, as well as complexes thereof, and NAD+ which enhance the oxidation reaction. The method described can act as a sobriety inducer and/or as an effective palliative for the unpleasant effects of overuse of ethanol.Type: GrantFiled: December 20, 2004Date of Patent: January 29, 2008Assignee: Wardan, L.L.C.Inventors: Ward B. Bowen, Jr., Daniel S. Daniel
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Patent number: 7303755Abstract: The use of certain salts and aminoacids as stabilizer of the antibiotic Fosfomycin Tromethamol and pharmaceutical compositions containing them, is described.Type: GrantFiled: July 10, 2003Date of Patent: December 4, 2007Assignee: Zambon S.p.A.Inventors: Luca Rampoldi, Luca Pirrone, Sarah Faccin, Alessandro Grassano, Giovanni Gurrieri
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Patent number: 7297349Abstract: The present invention relates to a copper-containing formulation for plant disease-control which comprises divalent copper and polyphosphate residues, wherein the amount of the polyphosphate residues per one chemical equivalent of the divalent copper is higher than one chemical equivalent. The copper-containing formulation of the present invention shows an excellent disease-control effect without causing any chemical injury of the plant.Type: GrantFiled: February 28, 2005Date of Patent: November 20, 2007Assignees: Riken, Otsuka Chemical Co., LtdInventors: Yutaka Arimoto, Akiko Hagiwara, Kiyoshi Uchida, Yoshifumi Ota
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Patent number: 7186420Abstract: A multi-part substitution infusion fluid for an extracorporeal blood treatment and methods for using same are provided. Generally, the multi-part substitution fluid comprises a first solution composed of electrolites but without divalent cations and a second solution comprising divalent cations. Another embodiment includes a third solution comprising a matching citrate/citric acid anticoagulant. The described methods of using the multi-part substitution infusion fluids significantly reduce risks associated with various extracorporeal blood treatments.Type: GrantFiled: December 19, 2003Date of Patent: March 6, 2007Assignee: Edwards Lifesciences CorporationInventors: Peter C. Chang, Jean-Michel Lannoy
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Patent number: 7175833Abstract: A glass composition having the general empirical formula given below, expressed in weight percent of the element: P: 16–24, F: 5–30, O: 20–40 and at least one of Na, K, Li or Al in an amount up to a total of 40 wt. % and optionally, up to 5 wt. % of boron and/or silicon. The composition may be used for the treatment and/or prevention of dental caries by providing a slow fluoride releasing device that may be attached to a tooth to release fluoride into the saliva or an individual.Type: GrantFiled: August 14, 2000Date of Patent: February 13, 2007Assignee: Teldent LtdInventor: Brian Algar
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Patent number: 7166290Abstract: The present invention provides improved methods and compositions for producing oocysts. The oocysts produced according to the invention find use in the manufacture of vaccines. In preferred embodiments, the present invention provides methods and compositions for the production of Eimeria oocysts. Vaccines containing Eimeria oocysts, sporocysts and/or sporozoites produced according to the present invention may be used to immunize birds against coccidiosis either in ovo or post hatch.Type: GrantFiled: August 29, 2002Date of Patent: January 23, 2007Assignee: Embrex, inc.Inventors: James E. Hutchins, Julius K. Tyczkowski
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Patent number: 7150879Abstract: The present invention provides a novel process for producing a calcium phosphate cement or filler which hardens in a temperature dependent fashion in association with an endothermic reaction. In the reaction a limited amount of water is mixed with dry calcium phosphate precursors to produce a hydrated precursor paste. Hardening of the paste occurs rapidly at body temperature an is accompanied by the conversion of one or more of the reactants to poorly crystalline apatitic calcium phosphate. The hardened cements, fillers, growth matrices, orthopedic and delivery devices of the invention are rapidly resorbable and stimulate hard tissue growth and healing.Type: GrantFiled: May 11, 2000Date of Patent: December 19, 2006Assignee: Etex CorporationInventors: Dosuk D. Lee, Christian Rey, Maria Aiolova, Aliassghar Tofighi
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Patent number: 7060301Abstract: The present invention relates to in situ compositions of mono- or diester dicarboxylates, methods employing these in situ compositions, and methods of making these in situ compositions. More particularly, the invention relates to mono- or diester dicarboxylate antimicrobial compositions that can reduce the population of microbes on various surfaces such as facilities, containers, or equipment found in food, beverage, or pharmaceutical processing, or in food, beverage, or pharmaceutical industries, at temperatures between about ?70° C. to about 100° C.Type: GrantFiled: July 13, 2001Date of Patent: June 13, 2006Assignee: Ecolab Inc.Inventors: Guang-Jong Jason Wei, Larry A. Grab, Robert Dale Hei, Teresa C. Podtburg
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Patent number: 7056536Abstract: A non-corrosive, liquid, aqueous sterilant composition (as a concentrate or ready-to-use solution), which may be provided in two parts which are mixed prior to application, may comprise a peracid (in an equilibrium solution with an underlying carboxylic acid or mixtures of alkyl carboxylic acids and peroxide), inorganic buffering agent, and water. It has been found that the use of this simplified system, even in the absence of additional components which have been thought to be desirable for sterilants used on metal parts (e.g.Type: GrantFiled: March 10, 2003Date of Patent: June 6, 2006Assignee: Ecolab Inc.Inventors: Francis L. Richter, Duane J. Reinhardt, Sally K. Swart
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Patent number: 7049319Abstract: A composition and method for cleansing a colon prior to endoscopic procedure. More particularly, a combination of bisacodyl, metoclopramide, sodium, and/or a phosphorus containing composition administered in sequential doses for preparing a colon prior to colonoscopy.Type: GrantFiled: September 23, 2003Date of Patent: May 23, 2006Inventor: Semaan Abboud
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Patent number: 6881424Abstract: A highly acidic metalated organic acid composition and its preparation. The acidic composition can be prepared by mixing a monovalent or polyvalent cation and an organic acid in the presence of a strong oxyacid, wherein the resultant acidic composition is less corrosive to a ferrous metal than a solution of a mineral acid having the same acidic pH value as that of the acidic composition, and where in the acid composition is more biocidal than a mixture of the organic acid and a metal salt of the organic acid which mixture has the same acid normality value as that of the acidic composition. The acidic composition can be prepared by mixing at least one regenerating acid, at least one metal base, and at least one organic acid, wherein the amount of the regenerating acid is in excess of the equivalent amount of the metal base.Type: GrantFiled: September 5, 2000Date of Patent: April 19, 2005Assignee: Mionix CorporationInventors: Maurice Clarence Kemp, Robert Blaine Lalum, David E. Lewis, Robert H. Carpenter
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Patent number: 6849275Abstract: A method for controlling the formation of a hydroxyapatite bone filler from dry calcium phosphate precursors in an aqueous solution uses coated sodium phosphate powder. The sodium phosphate powder is coated with a water soluble cellulose. Until the cellulose dissolves in the aqueous solution setting of the calcium phosphate cements proceeds slowly but when the exposed sodium phosphate particles start to solubilize in the aqueous solution the setting rate increases.Type: GrantFiled: January 10, 2003Date of Patent: February 1, 2005Assignee: Howmedica Osteonics Corp.Inventor: Paul Higham
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Patent number: 6833362Abstract: A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or “pseudo” enzymes for the oxidation. Additives include the oxidant Nicotinamide Adenine Dinucleotide and a variety of other additives such as transition metal ions and complexes thereof which favor the oxidation reaction. The compositions described can act as a sobriety inducer and/or as an effective palliative for the unpleasant effects of overuse of ethanol.Type: GrantFiled: June 7, 2001Date of Patent: December 21, 2004Inventors: Ward Beryl Bowen, Jr., Daniel Salman Daniel
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Patent number: 6824794Abstract: A water treatment agent and method of treating water to inhibit, reduce, or prevent the formation of algae and bacteria in a water body. The water treatment agent may include copper sulfate penta-hydrate and/or silver, di-sodium ethylene di-amine tetra-acetic acid dihydrate, a scale inhibitor, a shocking agent and a buffer agent. For instance, the treatment agent may include a composition of copper sulfate pentahydrate, di-sodium ethylene di-amine tetra-acetic acid, monopotassium phosphate or sulfuric acid, and potassium monopersulfate and 1-hydroxyethylidene-1,1-diphosphonic acid.Type: GrantFiled: May 31, 2002Date of Patent: November 30, 2004Assignee: Innovative Water Technologies, Inc.Inventors: Terry A. Ring, Tom Smolkov, M. Anthony Gamarra
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Patent number: 6803057Abstract: An acidic aqueous hydrogen peroxide solution is provided with improved disinfectant activity. Concentrated solutions preferably contain up to about 8 wt./wt. % H2O2 and as-used concentrations contain about 0.5% wt./wt. % H2O2. The solution also contains from 0.05 to 8.0 wt./wt. % of at least one phosphorous-based acid, e.g. phosphoric acid and/or a phosphonic acid with from 1 to 5 phosphonic acid groups, and from 0.02 to 5 wt./wt. % of at least one anionic surfactant. The surfactant is selected from C8 to C16 alkyl aryl sulfonic acids, sulfonated C12 to C22 carboxylic acids, C8 to C22 alkyl diphenyl oxide sulfonic acids, naphthalene sulfonic acids, C8 to C22 alkyl sulfonic acids, and alkali metal and ammonium salts thereof, and alkali metal C8 to C18 alkyl sulfates, and mixtures thereof. Most preferably the solution has an emulsifier and/or hydrotrope, e.g. an alkylated sulfonated diphenyl oxide salt, an alkyl aryl polyoxyethylene surfactant, and/or a polyoxyethylene surfactant.Type: GrantFiled: December 28, 2001Date of Patent: October 12, 2004Assignee: Virox Technologies Inc.Inventors: Jose A. Ramirez, Michael J. Rochon
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Patent number: 6764692Abstract: A method of treating laminitis in a horse is disclosed, comprising administering to the horse a naturally chelated trace mineral composition; promoting healthy skin, hair and hoof tissue. A method of reducing dietary intake is also disclosed, comprising administering to a horse in need thereof, effective amounts of a naturally chelated trace mineral composition. A method of preparing the chelated trace mineral composition from ocean seabed rock is further disclosed, as well as the chelated trace mineral composition.Type: GrantFiled: August 27, 2002Date of Patent: July 20, 2004Inventor: Carlos Cortelezzi
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Patent number: 6756060Abstract: Compositions and methods for treating wounds to significantly reduce the healing time, reduce the incidence of scar formation, improve the success of skin grafts, reduce the inflammatory response and providing anti-bacterial treatments to a patient in need thereof, that include small non-interlinked particles of bioactive glass or highly porous bioactive glass, are disclosed. Anti-bacterial solutions derived from bioactive glass, and methods of preparation and use thereof, are also disclosed. The compositions include non-interlinked particles of bioactive glass, alone or in combination with anti-bacterial agents and/or anti-inflammatory agents. The compositions can include an appropriate carrier for topical administration. Anti-bacterial properties can be imparted to implanted materials, such as prosthetic implants, sutures, stents, screws, plates, tubes, and the like, by incorporating small bioactive glass particles or porous bioactive glass into or onto the implanted materials.Type: GrantFiled: April 27, 2000Date of Patent: June 29, 2004Assignee: USBiomaterials Corp.Inventors: David C. Greenspan, Jon K. West, Sean Lee, James L. Meyers, Mason Diamond
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Patent number: 6723349Abstract: The invention relates to a polyoxometalate topical composition for removing a contaminant from an environment, comprising a topical carrier and at least one polyoxometalate, with the proviso that the polyoxometalate is not H5PV2Mo10O40; K5Si(H2O)MnIIIW11O39; K4Si(H2O)MnIVW11O39; or K5CoIIIW12O40. The invention further relates to a method for removing a contaminant from an environment, comprising contacting the polyoxometalate topical composition of the present invention with the environment containing the contaminant for a sufficient time to remove the contaminant from the environment. The invention further relates to a modified polyoxometalate, wherein the modified polyoxometalate comprises the admixture of (1) a polyoxometalate and (2) a cerium compound, a silver compound, a gold compound, a platinum compound, or a combination thereof.Type: GrantFiled: October 11, 2000Date of Patent: April 20, 2004Assignee: Emory UniversityInventors: Craig L. Hill, Ling Xu, Jeffrey T. Rhule, Eric A. Boring
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Patent number: 6689392Abstract: A composition for controlling growth of pathological organisms on a plant, said composition comprises an effective amount of one or more of metal ion(s); one or more of chelating agent(s); and phosphorous acid, and/or salt or hydrate thereof, said composition is in an agriculturally compatible carrier or vehicle.Type: GrantFiled: January 29, 2002Date of Patent: February 10, 2004Assignee: Agricare Ltd.Inventor: Ran Lifshitz
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Publication number: 20040009236Abstract: The invention provides compositions for rapid bowel cleansing comprising a mixture of polyethylene glycol and sodium phosphate(s). The compositions are particularly useful for preparing the bowel prior to surgery or diagnostic procedures such as colonoscopies. The invention further comprises methods for cleansing the bowel using these compositions, and bowel cleansing kits comprising these compositions.Type: ApplicationFiled: July 15, 2002Publication date: January 15, 2004Inventor: George M. Halow
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Patent number: 6620798Abstract: Methods for the repair, reconstruction and protection of tissue using compositions containing flavonoids and/or flavonols, including simultaneous administration of agents in order to obtain synergistic effects from the combinations taught and claimed herein. The administration of the flavonols and /or flavonoids in conjuction with compositions containing vitamin C and/or salts and esters of vitamin C provides advantageous sparing of autocoids (internal steroids). The simultaneous administration of flavonols and /or flavonoids to compositions containing glucosamine and or glucosamine sulfate and chondroitin stimulates rapid improvement in joint function. The addition to the flavonoids and/or flavonols to previously administered compositions is a most convenient method of achieving enhanced benefits. The use of combinations of flavonoids and flavonols for use in relieving pain is also a part of the invention.Type: GrantFiled: June 6, 2000Date of Patent: September 16, 2003Inventor: Russell Jaffe
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Patent number: 6589565Abstract: A non-corrosive, liquid, aqueous sterilant composition (as a concentrate or ready-to-use solution), which may be provided in two parts which are mixed prior to application, may comprise a peracid (in an equilibrium solution with an underlying carboxylic acid or mixtures of alkyl carboxylic acids and peroxide), inorganic buffering agent, and water. It has been found that the use of this simplified system, even in the absence of additional components which have been thought to be desirable for sterilants used on metal parts (e.g.Type: GrantFiled: November 22, 1999Date of Patent: July 8, 2003Assignee: Ecolab Inc.Inventors: Francis L. Richter, Duane J. Reinhardt, Sally K. Swart
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Patent number: 6565892Abstract: Synergistic fungicidal composition comprising a compound analogous to strobilurin of formula (I): in which: A is the nitrogen atom or the —CH group, B is the —OCH2— or —CH2O— or CH(CH3)—O—N═CH— or —CH═N—O—CH(CH3)— group or the group R1 is an alkyl group containing 1 to 4 carbon atoms, R2 is —OCH3 or —NHCH3, X is a halogen atom, the cyano group or an alkyl or haloalkyl group containing 1 to 4 carbon atoms, n is equal to 1 or 2, with, when n is equal to 2, the possibility of having different X groups, and at least one fungicidal compound B, and a process for the curative or preventive control of phytopathogenic fungi using the composition.Type: GrantFiled: July 3, 2001Date of Patent: May 20, 2003Assignee: Rhone-Poulenc AgrochimieInventor: Patrice Duvert
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Patent number: 6565891Abstract: A multinutrient nutritional supplement is provided that is designed to be most effective in optimizing health, increasing the immunity and decreasing the instances and severity of infection particularly among children.Type: GrantFiled: August 23, 2002Date of Patent: May 20, 2003Assignee: Tsar Health Private Ltd.Inventor: Ranjit Kumar Chandra
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Patent number: 6562378Abstract: A multinutrient nutritional supplement is provided that is designed to be most effective in optimizing health, increasing the immunity and decreasing the instances and severity of infection particularly among adolescents.Type: GrantFiled: August 16, 2002Date of Patent: May 13, 2003Assignee: TSAR Health Private Ltd.Inventor: Renjit Kumar Chandra
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Patent number: 6558709Abstract: A method for controlling the formation of a hydroxyapatite bone filler from dry calcium phosphate precursors in an aqueous solution uses coated sodium phosphate powder. The sodium phosphate powder is coated with a water soluble cellulose. Until the cellulose dissolves in the aqueous solution setting of the calcium phosphate cements proceeds slowly but when the exposed sodium phosphate particles start to solubilize in the aqueous solution the setting rate increases.Type: GrantFiled: January 5, 2001Date of Patent: May 6, 2003Assignee: Howmedica Osteonics Corp.Inventor: Paul Higham
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Patent number: 6541421Abstract: This invention relates to a buffered phosphorus containing solution comprising at least one phosphorus compound selected from the group consisting of phosphorous acid, hypophosphorous acid, polyphosphorous acid polyhypophosphorous acid, and salts thereof. The solution also contains a buffer including an organic base in the form of a nitrogen containing compound and its conjugate acid. The solution may be used as a fertilizer or as a fungicide. The invention also relates to a method of preparing such a solution.Type: GrantFiled: October 4, 2000Date of Patent: April 1, 2003Inventors: Alastair James Forsyth, Tomasz Antoni Modro
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Patent number: 6537589Abstract: An artificial bone promotive of osteoanagenesis comprising a calcium phosphate cement and a linear polyphosphate, wherein the calcium phosphate cement comprises &bgr;-tricalcium phosphate, monocalcium phosphate, calcium sulfate hemihydrate and other additives. The artificial bone is non-toxic to the body chemically stable, and has an excellent biodegradability. The artificial bone may be applied as substitutes for bone cements, allografts and autografts.Type: GrantFiled: July 25, 2000Date of Patent: March 25, 2003Assignee: Kyung Won Medical Co., Ltd.Inventors: Soo Kyung Chae, Hong Yeoul Kim, Ho Yeon Lee, Chang Hun Lee, Kang Moon Seo
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Patent number: 6538038Abstract: Treatment of warm-blooded animals having a tumor or non-malignant hypervascularation, by administering a sufficient amount of a cytotoxic agent formulated into a phosphate prodrug form having substrate specificity for microvessel phosphatases, so that microvessels are destroyed preferentially over other normal tissues, because the less cytotoxic prodrug form is converted to the highly cytotoxic dephosphorylated form.Type: GrantFiled: February 16, 2000Date of Patent: March 25, 2003Assignee: OXiGENE, Inc.Inventors: Ronald W. Pero, David Sherris
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Patent number: 6521264Abstract: A solid powder product with a Ca/P ratio of between 1.40 and 1.90 is prepared from tricalcium phosphate and tetracalcium phosphate. An aqueous solution containing calcium ions and phosphate ions with a Ca/P ratio higher than 0.20 and lower than 0.50 is prepared. The aqueous solution and the solid powder product and optionally water are mixed to obtain a mixture with a liquid/solid weight ratio of between 0.30 and 0.65 and a resulting paste with a Ca/P ratio of between 1.50 and 1.67.Type: GrantFiled: January 11, 2000Date of Patent: February 18, 2003Assignee: TeknimedInventors: Jean-Louis Lacout, Zinèb Hatim, Michele Frache-Botton
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Patent number: 6518247Abstract: In order to lower the painfulness of injection of the remedy containing the products of lignin basic hydrolysis and oxidation, pyrophosphate, NaCl and water the value of pH of the remedy is adjusted to a neutral one by the addition of HCl.Type: GrantFiled: May 15, 2001Date of Patent: February 11, 2003Assignee: Obschestvo s Ogranichennoi Otvetstvennostiju “Ligpharm”Inventors: Dmitriy Victorovich Petukhov, Valeriy Aphanasievich Trophimov, Vladimir Alexandrovich Philov, Valentina Vasilievna Reztsova, Boris Timopheievich Pinchuk
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Patent number: 6506392Abstract: A formulation consisting of sodium bicarbonate, sodium carbonate and trisodium phosphate in aqueous solution is applied topically to treat an array of skin and tissue problems. The solution offers antibacterial, antiseptic, anti-fungal, and healing properties to skin scratches, cuts, sores, and fungal infected nails. In addition, the solution dries as a thin film to the applied surfaces, continuously providing antibacterial, anti-fungal and antiseptic activity beneath the protective film long after it has been applied.Type: GrantFiled: January 26, 2001Date of Patent: January 14, 2003Inventor: Al Siamon
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Patent number: 6495168Abstract: This invention relates, generally, to nutritional supplements which contain bioactive glass. These supplements are useful in both veterinary and human contexts. The compositions of the subject invention can be used to achieve a number of advantageous results including: enhancing the growth rates of young animals, osteogenic stimulation, strengthening the skeletal structure, and treating osteoporosis.Type: GrantFiled: March 26, 2001Date of Patent: December 17, 2002Assignees: USTherapeutics, LLC, USBiomaterials CorporationInventors: Jon K. West, David Greenspan, James L. Meyers
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Patent number: 6475631Abstract: The present invention provides an antimicrobial agent consisting of glass which comprises 50 to 60 mole % of ZnO, 20 to 30 mole % of at least one member selected from the group consisting of B2O3 and P2O5, 1 to 10 mole % of at least one member selected from the group consisting of Al2O3 and ZrO2, 5 to 10 mole % of an alkali metal oxide and 0 to 15 mole % of SiO2 and an antimicrobial agent consisting of glass which comprises 50 to 70 mole % of ZnO, 20 to 35 mole % of P2O5, 0.5 to 10 mole % of Al2O3, 0.5 to 10 mole % of SnO2, 0 to 5 mole % of SiO2 and 5 to 10 mole % of an alkali metal oxide as well as an antimicrobial resin composition and antimicrobial artificial marble, each of which comprises a resin and the antimicrobial agent blended therewith. The antimicrobial resin composition and the antimicrobial artificial marble are excellent in their antimicrobial properties, resistance to color change and water resistance.Type: GrantFiled: July 14, 2000Date of Patent: November 5, 2002Assignee: Toagosei Co., Ltd.Inventors: Noriyuki Yamamoto, Koji Sugiura, Satoshi Yamato
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Patent number: 6448240Abstract: The invention concerns a synergetic fungicide and/or bactericide composition comprising famoxadone and a phosphorous acid derivative; and a method for fighting, for cure or prevention, against phytopathogenic fungi and/or bacteria using such a composition.Type: GrantFiled: August 10, 2000Date of Patent: September 10, 2002Assignee: Aventis CropScience, S.A.Inventors: Bernadette Givois, Marie-Pascale Latorse
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Patent number: 6432425Abstract: A formulation consisting of sodium bicarbonate, sodium carbonate and trisodium phosphate in aqueous solution is applied topically to treat an array of skin and tissue problems. The solution offers antibacterial, antiseptic, anti-fungal, and healing properties to skin scratches, cuts, sores, and fungus-infected nails. In addition, the solution dries as a thin film to the applied surfaces, continuously providing antibacterial, anti-fungal and antiseptic activity beneath the protective film long after it has been applied.Type: GrantFiled: September 8, 2000Date of Patent: August 13, 2002Inventor: Al Siamon
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Patent number: 6423343Abstract: This invention relates to a method for treating inflammatory symptoms such as burning, redness, itching, swelling and pain which accompany skin disorders other than wounds of the skin. The method comprising topical application of a topical medicinal composition comprising a non-interlinked, particulate bioactive glass mixed with a topical medicinal carrier to the site of the skin disorder.Type: GrantFiled: January 23, 1998Date of Patent: July 23, 2002Assignee: USBiomaterials CorporationInventors: Sean Lee, James L. Meyers
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Patent number: 6423348Abstract: What is shown is an animal blood anticoagulant compound useful in the meat packing industry generally, and in slaughterhouse operations, particularly. The anticoagulant is effective when diluted with water at higher dilution ratios than earlier anticoagulants. In some field trials, this anticoagulant was at least as effective as previously known commercial anticoagulants when diluted by an additional 30%. The present anticoagulant preparation concentrate is an aqueous mixture of soft water (55.0%-65.0/%, w/w); tetrasodium ethylene diamine tetraacetate (Na4EDTA) (0.5%-3.0%, w/w); sodium hexametaphosphate (17.0%-24.0%, w/w); citric acid (5.0%-9.0%, w/w); and sodium hydroxide (4.0%-7.0%, w/w) to obtain a balanced pH that provides optimal chelating and anticoagulant activity. Optimal anticoagulant performance has been found to occur in the range of between pH 6.6 and pH 7.2.Type: GrantFiled: December 15, 1998Date of Patent: July 23, 2002Inventor: James C. Mickus
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Patent number: 6410281Abstract: A process is provided for growing the microflora Thraustochytrium, Schizochytrium, and mixtures thereof, which includes the growing of the microflora in fermentation medium containing non-chloride containing sodium salts, in particular sodium sulfate. In a preferred embodiment of the present invention, the process produces microflora having a cell aggregate size useful for the production of food products for use in aquaculture. Further disclosed is a food product which includes Thraustochytrium, Schizochytrium, and mixtures thereof, and a component selected from flaxseed, rapeseed, soybean and avocado meal. Such a food product includes a balance of long chain and short chain omega-3 highly unsaturated fatty acids.Type: GrantFiled: December 14, 1999Date of Patent: June 25, 2002Assignee: Omegatech, Inc.Inventor: William R. Barclay
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Patent number: 6379711Abstract: Phosphomolybdic acid and partial alkali salts of phosphomolybdic acid are used as stabilizers for aqueous hydrogen peroxide.Type: GrantFiled: January 27, 2000Date of Patent: April 30, 2002Assignee: Crompton CorporationInventors: Peter Frenkel, Ted M. Pettijohn
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Patent number: 6358938Abstract: Synergistic fungicidal composition comprising propamocarb and a derivative of phosphorous acid; and process for the curative or preventative control of phytopathogenic fungi by use of such a composition.Type: GrantFiled: February 15, 2000Date of Patent: March 19, 2002Assignee: Rhone-Poulenc AgroInventors: Joëlle Donnadieu, Patrice Duvert, Richard Mercer
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Publication number: 20020031555Abstract: A formulation consisting of sodium bicarbonate, sodium carbonate and trisodium phosphate in aqueous solution is applied topically to treat an array of skin and tissue problems. The solution offers antibacterial, antiseptic, anti-fungal, and healing properties to skin scratches, cuts, sores, and fungal infected nails. In addition, the solution dries as a thin film to the applied surfaces, continuously providing antibacterial, anti-fungal and antiseptic activity beneath the protective film long after it has been applied.Type: ApplicationFiled: January 26, 2001Publication date: March 14, 2002Inventor: Al Siamon
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Patent number: 6355277Abstract: There is disclosed a method of improving the smoke suppressant characteristics of halogen-containing polymeric compositions which comprises adding to said polymeric compositions a smoke retardant amount of (1) a complex of a cuprous halide and a phosphite, and (2) an amine molybdate which contains no residual molybdenum trioxide prepared by reacting an amine with molybdenum trioxide in an aqueous acidic medium under greater than atmospheric pressure and at a temperature of from 105-150° C.Type: GrantFiled: July 14, 2000Date of Patent: March 12, 2002Assignee: Unitex Chemical CorporationInventors: James F. Day, Chad E. Lee
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Patent number: 6346279Abstract: An acidic aqueous hydrogen peroxid solution is provided, with improved disinfectant activity. Concentrated solutions preferably contain up to about 8% and as-used concentrations contain about 0.5% peroxide. The solution also contains from 0.1 to 5.0% of at least one acid compound, e.g. phosphoric and/or a phosphonate with from 1 to 5 phosphonic acid groups, and from 0.02 to 5% of at least one anionic surfactant. The surfactant is selected from C8 to C16-alkyl aryl sulphonic acids, sulphonated C12 to C22 carboxylic acids, C8 to C22-alkyl diphenyl oxide sulphonic acids, naphthalene sulphonic acids, C8 to C22 alkyl sulphonic acids, and alkali metal and ammonium salts thereof, and alkali metal C8 to C18 alkyl sulphates, and mixtures thereof. Most preferably the solution has an emulsifier, e.g. a salt of an alkylated diphenyl oxide. The solution may also contain corrosion inhibitors and/or lower alcohols.Type: GrantFiled: July 19, 1999Date of Patent: February 12, 2002Assignee: Virox Technologies, Inc.Inventor: Michael J. Rochon
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Publication number: 20010043951Abstract: Disclosed is a polyphosphate for use in promoting wound healing and scar abatement, represented by the following chemical formula 1. The polyphosphate can effectively promote the healing of wounds resulting from surgical operation or cutting without leaving scars, thereby encouraging patients to overcome loss of self-esteem. In addition, the medicinal aid can heal wounds effectively and economically while lessening scars.Type: ApplicationFiled: March 26, 2001Publication date: November 22, 2001Applicant: KYUNG WON MEDICAL CO., LTD.Inventors: Hong Yeoul Kim, Ho Yeon Lee
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Patent number: 6303155Abstract: A method for restoration of the circadian rhythm of parathyroid hormone (PTH) serum levels in a subject having osteoporosis, so as to restore a circadian rhythm of PTH levels which is similar to that existing in normal subjects is disclosed by administering a single daily dose of a composition consisting essentially of an effective amount of phosphate in the evening or at night, whereby the composition causes a circadian rhythm of PTH levels which peaks during the night, whereby the circadian rhythm of PTH levels is restored to that which is similar to that existing in normal subjects, thereby treating osteoporosis.Type: GrantFiled: March 1, 1999Date of Patent: October 16, 2001Assignee: Hadasit Medical Research Services and Development Company, Ltd.Inventor: Justin Silver
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Patent number: 6287548Abstract: The present invention provides a composition of matter which has been demonstrated to be a very effective treatment for acne, seborrheic dermatitis and related skin diseases when applied to and contacted with affected skin areas, while avoiding the disadvantages and complications attendant to more established treatments. The composition comprises a synthetic mixture of salts which, when dissolved in a solvent such as water, is ionically composed primarily of a mixture of sodium and magnesium cations and chloride and sulfate anions, and which is preferably free of added zinc. More specifically, the salt mixture according to the present invention comprises the following range of composition in grams/kilogram of salt mixture in the ionic state, the balance being water of hydration: I.Type: GrantFiled: November 21, 1994Date of Patent: September 11, 2001Assignee: Bio.Life International AGInventor: Hans F. Biener
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Patent number: 6277829Abstract: The present invention describes a process for the preparation of aqueous formulations containing azithromycin for ophthalmic use, as well any formulations obtained by this process and their topical use in the ocular bacterial infections, more preferably in the treatment of conjunctivitis, keratitis and blepharitis.Type: GrantFiled: December 27, 1999Date of Patent: August 21, 2001Assignee: S.I.F.I. Societa Industria Farmaceutica Italiana S.p.A.Inventors: Antonino Asero, Maria Grazia Mazzone, Valeria Moschetti, Anna Rita Blanco
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Patent number: 6197815Abstract: Metal amino acid chelates for animals are beneficial for facilitating and promoting growth by increasing desired metallic ion uptake. The present invention is directed to a process for providing an animal fed additive by preparing metal amino acid chelates, and the metal amino acid chelate growth facilitator, promoter and enhancer prepared by the process.Type: GrantFiled: March 18, 1998Date of Patent: March 6, 2001Assignee: J.H. Biotech, Inc.Inventor: Hsinhung John Hsu