Abstract: A non-staining composition which is bactericidal, fungicidal and viricidal when applied, comprising in combination; an iodine free bactericide and/or fungicide having a residual efficacy lasting longer than 3 hours on surfaces against bacteria and fungi and a peroxide. A carrier may also be present. The bactericide and/or fungicide may be for example triclosan or a quaternary ammonium compound, or preferably a PVP-phenolic biocide complex (eg PVP-triclosan) or PVAIc/quaternary ammonium compound complex (eg PVP/benzalkonium chloride). The peroxide may be hydrogen peroxide.

Abstract: The present invention relates to a toothpaste comprising one or more micronized unencapsulated peroxide compounds with improved properties with regard to cleaning and visual brightening of natural teeth, false teeth and/or polymer fillings of teeth; to its production and use.

Abstract: The present invention relates to compositions including medium chain peroxycarboxylic acid, methods for making these compositions, and methods for reducing the population of a microorganism. The compositions can include advantageously high levels of the medium chain peroxycarboxylic acid, can be readily made, and/or can exhibit reduced odor.

Abstract: A method for treating conditions related to lack of blood supply with a resuscitation fluid is disclosed. The resuscitation fluid contains a lipophilic component and a polar liquid carrier. The lipophilic component forms an emulsion with the polar liquid carrier. The resuscitation fluid can be used to increase the blood pressure and to carry oxygen and other lipophilic gases to tissues. The resuscitation fluid can also be used for preserving the biological integrity of donor organs for transplantation.

Abstract: One aspect of the invention relates to isoform-selective HDAC inhibitors. Also provided are methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy. The invention also provides methods for treating cancer, methods for treating neurological diseases and methods for treating malaria. Additionally, the invention provides pharmaceutical compositions comprising an HDAC inhibitor of the invention; and kits comprising a an HDAC inhibitor of the invention.

Abstract: Head and neck squamous cell carcinomas (HNSCC) represent a group of metastasizing tumors with a high mortality rate in man and animals. Since the biomolecule ozone was found to inhibit growth of various carcinoma cells in vitro we here applied the highly aggressive and lethal VX2 carcinoma HNSCC tumor model of the New Zealand White rabbit to test whether ozone exerts anti-tumorous effects in vivo. Therapeutic insufflation of medical ozone/oxygen (O3/O2) gas mixture into the peritoneum (O3/O2-pneumoperitoneum) at an advanced stage of tumor disease led to a survival rate of 7/14 rabbits. Six of the seven surviving rabbits presented full tumor regression and the absence of local or distant lung metastases. Insufflation of pure oxygen (O2) resulted in a survival rate of 3/13 animals accompanied by full tumor remission in two of the three surviving animals. Of the fourteen sham-treated animals only one had spontaneous tumor remission and survived.

Abstract: The glass flake of the present invention has a composition that includes, in terms of mass %, 60<SiO2?65, 8?Al2O3?15, 47?(SiO2—Al2O3)?57, 1?MgO?5, 18?CaO?30, 0<Li2O?4, 0<(Li2O+Na2O+K2O)?4, and 0?TiO2?5, and that is substantially free from B2O3, F, ZnO, BaO, SrO, and ZrO2.

Abstract: This invention relates to a method for enhanced sanitation and oxidation of aqueous solutions at aquatic facilities. The method provides a means for the in-situ generation of chlorine dioxide from dilute solutions of chlorite anions at near neutral pH, and enhanced inactivation rates of microbiological organisms including cryptosporidium.

Abstract: The present invention relates to the use of combinations of 4-bromo-2-(4-chloro-phenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile and an oxidizing agent, for eradicating, eliminating or reducing aquatic organisms in ballast water or bilge water whereby 4-bromo-2-(4-chloro-phenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile and the oxidizing agent are in respective proportions to provide a synergistic effect against fouling organisms. Suitable oxidizing agents are e.g.

Abstract: The present invention relates to a preparation for sterilizing or disinfecting a tissue which has an excellent tissue sterilizing or disinfecting ability and is suitable for therapeutic or prophylactic treatment of various diseases caused by a microorganism such as a bacterium or a virus and a method for sterilizing or disinfecting a tissue. The present invention relates to a preparation for sterilizing or disinfecting a tissue and an agent for therapeutic or prophylactic treatment of a periodontal disease, characterized by containing a gas in a nanobubble state. Furthermore, the present invention relates to the above-mentioned preparation for sterilizing or disinfecting a tissue, characterized in that the above-mentioned gas in a nanobubble state is ozone. Furthermore, the present invention relates to a liquid preparation for sterilizing or disinfecting a tissue, characterized by comprising ozone-nanobubble water.

Abstract: A device for providing improved wound healing is described. The device includes a vacuum system for applying a sub-atmospheric pressure to the wound, a gas supply system for applying a gaseous wound healing agent to the wound, and a controller connected with the vacuum system and the gas supply system that controls the applications of the sub-atmospheric pressure and the application of the gaseous wound healing agent to the wound. A method of using the device for improved wound healing is also described.

Abstract: An ophthalmic solution comprising a hydrogen peroxide source in an amount sufficient to result in between about 0.001% and about 0.01% by weight stabilized hydrogen peroxide in said formulation as a preservative, one or more ocularly-compatible hydrogen peroxide stabilizers, hydroxypropylmethylcellulose and sodium carboxymethylcellulose, as well as pharmaceutical compositions comprising such solutions, are provided.

Abstract: A method of treating hypoxic tissue such as wound tissue comprises contacting a composition to the hypoxic tissue in a hypoxia-treatment effective amount, the composition comprising a biodegradable polymer and an inorganic peroxide incorporated into the polymer.

Abstract: Disclosed is a method for controlling microbial growth in an aqueous system containing sulfite and/or bisulfite residues by addition of a peroxy compound at a pH of greater than 5. Also disclosed is a method for stabilizing an active halogen biocide in an aqueous system containing peroxide residues by addition of an N-hydrogen compound to the active halogen biocide before combining it with the peroxide containing aqueous system. Further disclosed is an optimized papermaking biocide program consisting of initially treating sulfite bleached pulp with peroxide followed by application of an N-hydrogen-stabilized active halogen compound to the paper producing white waters and an analytical method for determining peroxide concentrations in aqueous systems in the presence of sulfite and/or bisulfite.

Abstract: Provided is a biocidal composition comprising glutaraldehyde and an oxazolidine biocidal compound. The composition is useful for controlling microorganisms in aqueous or water containing systems such as found in oil and natural gas production.

Abstract: A method for producing a deposition product includes providing a deposition solution having a pH below 7 and comprising an aqueous solution of a silver salt comprised of silver ions and an oxidizing agent. The silver salt is comprised of silver nitrate and has a concentration in the deposition solution between about 1 and 20 grams per liter. The oxidizing agent is comprised of a persulfate and has a concentration in the deposition solution between about 1 and 50 grams per liter. The method further includes producing the deposition product by facilitating a chemical reaction between the silver ions and the oxidizing agent while maintaining the deposition solution at a temperature of between about 2 and 40 degrees Celsius. The deposition product consists essentially of at least one oxidized silver species, and is comprised of a compound having the formula Ag7O8X, where X is an anion.

Abstract: The present invention is drawn to disinfectant or sterilant compositions, which are human safe, e.g., food grade or food safe. In one embodiment, an aqueous disinfectant or sterilant composition can comprise an aqueous vehicle, including water, from 0.001 wt % to 50 wt % of a peracid, and from 0.001 wt % to 25 wt % of a peroxide. Additionally, from 0.001 ppm to 50,000 ppm by weight of a transition metal based on the aqueous vehicle content can also be present. The composition can be substantially free of aldehydes. Alternatively or additionally, the transition metal can be in the form of a colloidal transition metal.

Abstract: This invention relates to aqueous solutions of reactive chlorine compounds having the empirical formulae H2Cl2O6 or ClO3H, for example, and the derivatives, anions or salts thereof. The invention further relates to methods for the production of said compounds and the use thereof in the pharmaceutical and particularly in the medical field, in cosmetics, medicinal care and in the domains of food technology and technology.

Abstract: This invention relates to a composition for use in the treatment of pathogenic microorganisms in a live animal, the composition comprising an electro-chemically activated, anion-containing aqueous solution.

Abstract: The present invention relates to a method of inhibiting biofilms by combinations of antimicrobials, particularly with their synergistic activity against bioFilms. The antimicrobials include combination of copper ion and quaternary ammonium compound or combination of copper ion and peroxide. The invention also include methods for inhibiting biofilm-induced microbial corrosion or fouling.

Abstract: A composition of stabilized chlorine dioxide at a concentration range of about 0.0004% to about 0.8% (w/v) having anti fungal properties to prevent oral fungal infections and method of use are disclosed.

Abstract: An aqueous solution which retains a high residual chlorine concentration over a long life and has excellent disinfectant (bactericidal) ability. The aqueous solution contains at least one member selected from the group consisting of halogen acids and salts thereof and further contains active oxygen, wherein the halogen acids are at least one member selected from the group consisting of hypochlorous acid, chlorous acid, chloric acid, and perchloric acid, the total amount of the at least one member selected from the group consisting of the halogen acids and salts thereof and contained in the aqueous solution is 10-50,000 ppm, and the total amount of the active oxygen contained in the aqueous solution is 0.1-1,000 ppm.

Abstract: Compositions and methods for their use are presented that substantially increase the rate of inactivation of microbiological organisms, especially those resistant to inactivation from free halogen based sanitizers, and oxidation of oxidation resistant organic based compounds in aqueous solution.

Abstract: A pharmaceutical formulation that is effective in adversely affecting the viability of microorganisms or in inhibiting their growth and that provides better safety and/or comfort to the users comprises a polysaccharide, a source of hydrogen peroxide, and an anti-oxidant. The formulation can further comprise a chelating agent and/or an ophthalmically active agent for treating or controlling a disease or disorder of the eye. The formulation may be used to treat, clean, disinfect, store, wet, or rewet contact lenses.

Abstract: This invention comprises a composition and the process of using the composition for removing and preventing mold, mildew, and fungal growth. The composition comprises at least one alkali metal perborate, at least one inhibiting compound selected from the group consisting of alkali metal silicates, triazoles and mixtures thereof in any ratio, at least one corrosion inhibitor, and effective amounts of surfactant.

Abstract: A method is disclosed for treatment of urinary incontinence. The method includes the steps of providing to a person or animal, in the vicinity of a pubo-urethral ligament of the person or animal, a composition including collagen macromolecules that have hydroxyphenyl side groups substituted thereon, which are reacted to form dihydroxyphenyl linkages. In an embodiment, the collagen macromolecules are gelatin macromolecules. In another embodiment, the hydroxyphenyl side groups are tyramine side groups and the dihydroxyphenyl linkages are dityramine linkages. The composition can be injected into a space between a urethra and a pubis of the person or animal wherein the pubo-urethral ligament is disposed in the space. The method is advantageous, for example, based on being minimally invasive.

Abstract: Provided is a method of decontaminating an area, and related device. The method comprises releasing a germicidal agent into the area from a germicidal source, controlling the germicidal agent concentration in the area to a predetermined concentration that does not exceed a Permissible Exposure Limit, and contacting microorganisms in the area with the germicidal agent to decontaminate the area. The device comprises a releasing mechanism configured to release a germicidal agent from a germicidal source at a predetermined concentration into the area such that the predetermined concentration of germicidal agent in the area does not exceed a Permissible Exposure Limit.

Abstract: The present invention refers to a pharmaceutical preparation for treating inflammatory diseases and microbial infections comprising a pharmaceutically effective amount of ozone and at least one monomeric amino acid having an oxidation-sensitive side chain, or at least one ozonized monomeric amino acid having an oxidation-sensitive side chain. Also described is the use of a preparation as described before for providing a medicament for treating inflammatory diseases, microbial infections and for immune modulation. The pharmaceutical preparation according to the invention is particularly useful in the treatment of oral inflammations.

Abstract: An oxidizing liquid (20), such as hydrogen peroxide, is vaporized (18) and the vapor is used to deactivate nerve gas, blistering gas, or other biologically active substances such as pathogens, biotoxins, and prions. A second chemical compound (42) in vapor, mist, or fog form is used in conjunction with the oxidizing vapor. In one embodiment, the second chemical preconditions the biologically active substances to be deactivated more efficiently by the oxidizing vapor. In another embodiment, the second chemical boosts the reactivity of the oxidizing vapor. In another embodiment, the other chemical reacts with the oxidizing vapor to form an intermediate compound that deactivates at least some of the biologically active substances.

Abstract: The method to increase and accelerated rehabilitate the capacity for work is characterized in that the person is exposed to gaseous products having the property to improve physical and psychological human capabilities during a period of preparing for extreme strains and/or after extreme strains; the exposure to gaseous products is performed during a period from several weeks to several minutes before undergoing extreme strains by inhaling the gaseous mixture composed of oxygen and/or air and at least one inert gas, mainly xenon, with the contents of oxygen or air from 20% to 98% and at least one inert gas from 2% to 80%. The inhalation with the gaseous mixture is carried out until the state of euphoria emerges but no longer than for 20 minutes with breaks or without them; preferably, the inhalation with the gaseous mixture is performed no less than for 10 seconds and no longer than for 20 minutes with breaks or without them.

Abstract: The common link between incurring a heart attack, suffering a stroke or diabetic crisis is related to deficiencies involving a body's metabolism of glucose and the ability to optimally conduct the necessary biologic processes of aerobic respiration to produce energy molecules. Utilizing a medical treatment method comprised of a modified form of virus to deliver to cells in the body the protein molecules and nutrients needed to enhance the processes of glycolysis, the tricarboxylic acid cycle, oxidative phosphorylation and anaerobic respiration will save lives. Providing an alternative means for brain cells and heart muscle cells to have access to proteins, nutrients such as glucose and oxygen, and energy molecules by providing these tissues with viruses that carry these vital elements to these tissues will greatly improve the survivability of individuals experiencing a heart attack, a stroke or a diabetic crisis.

Abstract: The present disclosure is drawn to disinfectant hand sanitizing compositions. In one embodiment, a hand sanitizing compositions can include from 10 to 1500 ppm colloidal silver, from 0.01 wt % to 30 wt % alcohol, at least 70 wt % water, and a thickening agent. The hand sanitizers can provide continued sanitization for an extended period of time and can be formulated to be dispensed as self-supporting foams.

Abstract: Compositions and methods that yield chlorine dioxide upon mixing with an aqueous solution.

Abstract: The present invention is directed to attaching drugs and other functional groups to surfaces of nano-sized diamonds (NDs) to enhance the efficacy of drugs and other substances. The method involved enhancing the efficacy of a drug having an active site by acquiring a plurality of nanodiamond (ND) particles having a plurality of carbon chain surface molecules on its surface. Intermediate amine entities are covalently attached to the surface molecules of the ND particles. These are then replaces with said drug molecules such that the active sites of said drug molecules point away from the ND particle exposing them for enhanced activity and enhanced drug efficacy. The efficacy of antimicrobial drugs are enhanced, however, this may be used with many different types of drugs.

Abstract: The invention relates to an aqueous oxidant for hair treatment which comprises the following, by weight based on the total weight of the oxidant: 1) 3 to 15% of a peroxide and/or a persulfate; 2) 0.05 to 2% of at least one perfume containing: •5 to 100%, by weight based on the weight of the perfume, of olfactory substances having at least one ester group, and •0 to 95% by weight based on the weight of the perfume, of olfactory substances having at least one alpha, ?-unsaturated ketone group, said olfactory substances being stable in the presence of peroxide; 3) 0.1 to 5% of a solubilizer; and 4) 0.005 to 2% of a sequestering agent. Application: cosmetic composition for coloring or bleaching the hair.

Abstract: The invention relates to a method for inhibiting the biological acidification of water which is in contact with materials containing sulfur in reduced form or with elemental sulfur, susceptible to oxidation on the part of Thiobacilli, comprising putting said materials in contact with soluble inorganic salts at concentrations ranging from 0.4 normal to saturation.

Abstract: The present invention relates to compositions including medium chain peroxycarboxylic acid, methods for making these compositions, and methods for reducing the population of a microorganism. The compositions can include advantageously high levels of the medium chain peroxycarboxylic acid, can be readily made, and/or can exhibit reduced odor.

Abstract: Provided is a disinfectant which is not harmful to the human body and has sterilizing power in atmospheric conditions. Liquid paraffin or Vaseline containing ozone is applied on the human body, or medical equipment to be disinfected is dipped therein. Thus, the disinfection of medical equipment is easily and conveniently achieved. When used on the human body, the disinfectant aids in the treatment of wounds because the disinfectant has a disinfection effect and a moisturizing effect.

Abstract: Novel formulations containing a non-oxidative biocide, such as DBNPA, and a source of an in situ produced active biocide, such as a concentrated aqueous solution of an inorganic halide salt, are disclosed. These novel formulations are particularly effective in the treatment of water, and are characterized by high stability, desirable rheological properties and an excellent biocidal activity.

Abstract: Sterilization methods and apparatus are effective to achieve a 6-log reduction in CFUs of industry standard bacteria and bacterial spores, i.e., B. stearothermophilus and B. subtilis spores, by subjecting sterilizable materials to a chemical additive-containing carbon dioxide sterilant fluid at or near its supercritical pressure and temperature conditions. Most preferably, the chemical additive-containing supercritical carbon dioxide sterilant fluid is agitated during sterilization, e.g., via mechanical agitation or via pressure cycling.

Abstract: The corrosion inhibiting mildew remover kit includes a premeasured amount of sodium perborate, a premeasured amount of a liquid inhibitor and a premeasured amount of a liquid blend. The premeasured amount of sodium perborate, the premeasured amount of liquid inhibitor, the premeasured amount of liquid blend and water combine to form an aqueous solution that can be applied to a mildew infected area. The aqueous solution removes mildew from a mildew infected area and does not cause corrosion.

Abstract: Disclosed are methods and compositions for increasing tissue oxygen levels by administration of superoxygenated compositions of tissue surfaces. The methods are applicable to treatment of a wide variety of conditions including burns, bedsores, ulcers, necrosis and anaerobic infections.

Abstract: Use of metal complex compounds of formula [LnMemXp]zYq??(1), wherein Me is manganese, titanium, iron, cobalt, nickel or copper, X is a coordinating or bridging radical, n and m are each independently of the other an integer having a value of from 1 to 8, p is an integer having a value of from 0 to 32, z is the charge of the metal complex, Y is a counter-ion, q=z/(charge Y), and L is a ligand of formula wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 are each independently of the others hydrogen; unsubstituted or substituted C1-C18alkyl or aryl; cyano; halogen; nitro; —COOR12 or —SO3R12 wherein R12 is in each case hydrogen, a cation or unsubstituted or substituted C1-C18alkyl or aryl; —SR13, —SO2R13 or —OR13 wherein R13 is in each case hydrogen or unsubstituted or substituted C1-C18alkyl or aryl; —N(R13)—NR?13R?13 wherein R13, R?13 and R?13 are as defined above for R13; —NR14R15 or —N?R14R15R16 wherein R14, R15 and R16 are each independently of the other(s) hydrogen or unsubstituted or s

Abstract: The present invention relates to systems and methods for producing disease and pest control agent for plants and crops containing dissolved oxygen and ozone. This present invention of disease and pest control agent for plants and crops containing dissolved microbubbles of oxygen and ozone consists of 0.3-40 ?m pore size microbubbles of ozone (03) 1.0-10.0 volume % and oxygen (O2) 99.0-90.0 volume % dissolved in water as colloids and the concentration of ozone in this solution is 1˜30 mg/l. This invention produces disease and pest control agent for plants and crops that contains microbubbles consisting of highly concentrated oxygen and ozone dissolved in water as colloid which is environmentally friendly and highly effective as pesticidal and germicidal agent.

Abstract: There are provided vaginal rinse compositions, consisting essentially of :a) 1-20 wt % of a mucosally acceptable peroxide, b) 0.5-15 wt % of a mucosally acceptable sulfate, bisulfate, pyrosulfate salt of an inorganic cation or mixtures thereof, and c) water to 100 wt %. There are further provided methods of preparing and using said compositions as well as kits for maintaining the components to prepare said compositions.

Abstract: This invention comprises a composition and the process of using the composition for removing and preventing mold, mildew, and fungal growth. The composition comprises at least one alkali metal perborate, at least one inhibiting compound selected from the group consisting of alkali metal silicates, triazoles and mixtures thereof in any ratio, at least one corrosion inhibitor, and effective amounts of surfactant.

Abstract: The present invention relates to the use, as oxidation catalysts, of metal complex compounds having tetradentate ligands of formula (2) wherein all substitutents have the meanings as defined in Claim 1. The present invention relates also to formulations comprising such metal complex compounds, to novel metal complex compounds and to novel ligands.

Abstract: Functional polymer compositions and methods of forming such compositions are provided. The functional polymer compositions include at least 50 wt % of one or more polymer components; from 0.1 to 50 wt % of one or more fluids; and from 1 to 50 wt % of one or more active substrates. The combination of one or more fluids and one or more active substrates provides an article from such polymer composition with one or more special functional effects selected from moisturizing, anti-bacterial, disinfecting, anti-viral, anti-mildew, anti-mold, anti-fungal, anti-microbial, moisture/odor absorbing, fragrancing, insect repelling, anti-static and combinations thereof. The one or more fluids and one or more active substrates are released to the surface of polymer based articles. The functional polymer compositions are suitable for a wide range of end use applications including woven and non-woven fabrics.

Abstract: The present invention relates to a method for using gas exchange modules for adjusting a pH value of blood in order to, e.g., adjust a non-physiological pH in patients treated with drugs whose activity optimum is in a non-physiological pH or to bring the pH to a physiological value.

Abstract: A process for making oil which is rich in ozone in the form of a gel comprises the steps of introducing olive oil in liquid form and ozone into a reaction chamber; in which during the contact step there is a step of controlled cooling of the reaction chamber in controlled pressure conditions, until a stable gel has been formed.