Sodium Containing Patents (Class 424/615)
  • Patent number: 7105183
    Abstract: The invention features methods of treating a macrophage-associated neurodegenerative disease such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), or multiple sclerosis (MS) in a subject by administering chlorite in an amount effective to decrease blood immune cell activation. The invention also features methods of monitoring therapy by assessing blood immune cell activation before and after therapy.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: September 12, 2006
    Assignee: The Regents of the University of California
    Inventor: Michael S. McGrath
  • Patent number: 7094430
    Abstract: An antimicrobial solution is provided for use in the cleaning of dentures and toothbrushes, as well as, for use as an oral mouthwash and/or a general disinfectant. The primary active ingredients of the present invention include an approximately 4.5% solution of hydrogen peroxide as an antibacterial agent and sodium lauryl sulfate as a cleansing agent. The present invention is mixed and maintained in liquid form. Additional ingredients are included to ensure the activation of the various antibacterial or cleansing agents. The present invention overcomes the problems with presently available denture cleansers because it does not require the use of hot, warm, or even cold water to activate the cleansing agent.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: August 22, 2006
    Assignee: Innovative Healthcare Products, Inc.
    Inventors: Grady F. Lawrence, W. Timothy Carlton
  • Patent number: 7087251
    Abstract: A method of eradicating or at least substantially reducing biofilm on a surface in contact with water, or which comes in contact with water, which method comprises introducing into such water a concentrated aqueous biocidal composition formed from bromine chloride and an aqueous solution of an alkali metal salt of sulfamic acid, such composition having an active bromine content of at least about 100,000 ppm (wt/wt), a pH of at least about 7, and an atom ratio of nitrogen to active bromine of greater than 0.93.
    Type: Grant
    Filed: October 28, 2002
    Date of Patent: August 8, 2006
    Assignee: Albemarle Corporation
    Inventor: Christopher J. Nalepa
  • Patent number: 7014871
    Abstract: An iodine preparation composition suitable for use on wounds comprising an iodide source, an oxidant and a buffer characterized in that the iodide is held separately from the oxidant until the point of use, and that the buffer is capable of maintaining the pH of the composition at between pH 45 and pH 6 so that iodine is generated at a physiologically acceptable dose rate.
    Type: Grant
    Filed: March 13, 2000
    Date of Patent: March 21, 2006
    Inventors: Dave Parsons, Elizabeth Jacques, Philip Bowler
  • Patent number: 6929790
    Abstract: The present invention relates to an oral composition containing a zinc compound containing free available zinc ion and at least one stabilized or stable Eh raising compound distributed in an oral vehicle. The present invention further relates to a method of inhibiting the formation of sulfur containing anions and preventing a reduction in the Eh of the oral cavity. A method of reducing oral malodor and gingivitis and periodontitis is also provided by this invention.
    Type: Grant
    Filed: June 24, 2002
    Date of Patent: August 16, 2005
    Assignee: The Research Foundation of State University of New York
    Inventors: Israel Kleinberg, Milroy Codipilly
  • Patent number: 6866870
    Abstract: A biocide composition is formed from a peroxide and a hypochlorite, wherein the biocide composition is formed by adding the peroxide to the hypochlorite in an amount so that the weight ratio of the hypochlorite to the peroxide is no less than about 10:1. A method of producing a biocide composition is carried out by charging to a vessel a quantity of a hypochlorite, and then adding to the hypochlorite so charged a quantity of a peroxide, the weight ratio of the hypochlorite so charged to the peroxide added thereto being no less than about 10:1. A related method is practiced by applying a biocidally effective amount of the biocide composition of the invention to a surface to be decontaminated.
    Type: Grant
    Filed: September 10, 2003
    Date of Patent: March 15, 2005
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College through the LSU AgCenter
    Inventor: Donal F. Day
  • Patent number: 6861075
    Abstract: A storage-stable biocidal aerated gel composition comprises from 30 to 97% by weight of water, from 0.2 to 5% by weight of a gelling agent selected from xanthan gum, sodium alginate and neutralised carboxyvinyl polymer from 2 to 5% by weight of a fine particulate, hydrophobic silicone-treated silica having a surface area of from 80 to 300 m2/g and from 0.004 to 20% by weight of a biocide which said composition is in the form of fine particles of an aqueous gel containing the water, gelling agent and the biocide, the surfaces of which fine particles are coated with a coating of the finely particulate hydrophobic silica. The biocidal aerated gel composition can be used to control pests using one or more appropriate biocides in the composition.
    Type: Grant
    Filed: April 6, 2001
    Date of Patent: March 1, 2005
    Assignee: Sorex Limited
    Inventor: Roland S. Twydell
  • Patent number: 6824794
    Abstract: A water treatment agent and method of treating water to inhibit, reduce, or prevent the formation of algae and bacteria in a water body. The water treatment agent may include copper sulfate penta-hydrate and/or silver, di-sodium ethylene di-amine tetra-acetic acid dihydrate, a scale inhibitor, a shocking agent and a buffer agent. For instance, the treatment agent may include a composition of copper sulfate pentahydrate, di-sodium ethylene di-amine tetra-acetic acid, monopotassium phosphate or sulfuric acid, and potassium monopersulfate and 1-hydroxyethylidene-1,1-diphosphonic acid.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: November 30, 2004
    Assignee: Innovative Water Technologies, Inc.
    Inventors: Terry A. Ring, Tom Smolkov, M. Anthony Gamarra
  • Patent number: 6790463
    Abstract: The use of a pharmaceutical formulation in treating coronary arteriosclerosis and a two-component pharmaceutical formulation. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by an oxygen-containing oxidizing agent, such as ozone; a penetrating solvent, such as dimithyl sulfoxide; a dye containing a chelated metal, such as hematoporphyrin; and an aromatic redox compound, such as benzoquinone.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: September 14, 2004
    Inventors: Robert F. Hofmann, Robert H. Carpenter
  • Patent number: 6753016
    Abstract: A method for the protection of wood and other wood materials without affecting dimensional stability or surface integrity of the treated material is described. The method involves treating wood material with an iron salt and selected oxidants where the iron salt is preferably complexed with organic chelating ligands. Preferably, a microbicidal agent is also incorporated into the method to provide treated wood products that demonstrate excellent surface integrity, dimensional stability and retention of the infused microbicidal agents for extended periods of time without incurring the detrimental environmental effects of conventional chromium or copper-based inorganic salt preservation methods.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: June 22, 2004
    Assignee: Rohm and Haas Company
    Inventor: Tirthankar Ghosh
  • Patent number: 6733798
    Abstract: The present invention includes a cranberry seed oil, a cranberry flour and a method for making cranberry seed oil and flour. The cranberry seed oil comprises beta sitosterol and phosphatidylcholine.
    Type: Grant
    Filed: May 20, 2002
    Date of Patent: May 11, 2004
    Inventors: Tim Heeg, Bernard G. Lager, II
  • Publication number: 20040047915
    Abstract: A biocide composition is formed from a peroxide and a hypochlorite, wherein the biocide composition is formed by adding the peroxide to the hypochlorite in an amount so that the weight ratio of the hypochlorite to the peroxide is no less than about 10:1. A method of producing a biocide composition is carried out by charging to a vessel a quantity of a hypochlorite, and then adding to the hypochlorite so charged a quantity of a peroxide, the weight ratio of the hypochlorite so charged to the peroxide added thereto being no less than about 10:1. A related method is practiced by applying a biocidally effective amount of the biocide composition of the invention to a surface to be decontaminated.
    Type: Application
    Filed: September 10, 2003
    Publication date: March 11, 2004
    Inventor: Donal F. Day
  • Patent number: 6663902
    Abstract: The present invention relates to a biocidal composition, designed for the generation of chlorine dioxide, comprising at least one iodo-compound having at least one iodine atom and a source of chlorite ions. The molar ration of chlorite ions to iodine atoms is 2 or greater. The composition finds use in a variety of applications including methods of cleaning, sanitizing, deodorizing, and disinfecting various surfaces.
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: December 16, 2003
    Assignee: Ecolab Inc.
    Inventors: Robert D. P. Hei, David Daniel McSherry, Kim R. Smith, Keith E. Olson
  • Patent number: 6660307
    Abstract: Active bromine-containing solutions are produced and stabilized by reacting bromate and bromide salt solutions with an amino-complexing agent, such as sulfamic acid or sulfamate salt. The reaction is performed at a pH of less than 1 to create a complexed hypobromate. The pH of the active bromine-containing solution is raised to between 4 and 10 by adding an alkali to improve stability. Moreover, the solution is maintained below 30° C. during the alkali addition to retain bromine equivalent activity.
    Type: Grant
    Filed: April 16, 2001
    Date of Patent: December 9, 2003
    Assignee: United States Filter Corporation
    Inventors: Vadim Zolotarsky, Irina A. Ivanter, Tamara Oustinskaya
  • Patent number: 6652889
    Abstract: Described is a process of producing a concentrated liquid biocide formulation. Mixed together are (a) bromine chloride or bromine and (b) an aqueous solution of alkali metal salt of sulfamic acid having a pH of at least about 7, in amounts such that (i) the active bromine content of the solution is at least about 100,000 ppm (wt/wt), and (ii) the atom ratio of nitrogen to active bromine from (a) and (b) is greater than 1 when bromine is used and is greater than 0.93 when bromine chloride is used. Use of bromine chloride as the source of the active bromine in the process is preferred because in the resulting aqueous compositions, all of the bromine of the bromine chloride is made available as active bromine in solution. In other words, the chlorine of the bromine chloride is converted in the process to dissolved alkali metal chloride salt, thereby liberating all of the bromine in the biocidal composition as active bromine capable of providing biocidal activity.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: November 25, 2003
    Assignee: Albemarle Corporation
    Inventors: Robert M. Moore, Jr., Christopher J. Nalepa
  • Patent number: 6572843
    Abstract: A method for treating hair, combining permanent dyeing and straightening of hair, without significantly damaging the hair. According to the method of the present invention the hair is treated by chemically reducing covalent disulfide linkages in the hair, and contacting said hair with at least one oxidoreductase, at least one mediator, and at least one chemical oxidizing agent in an amount equivalent to 0.001-1% hydrogen peroxide calculated by weight of the dyeing formulation.
    Type: Grant
    Filed: March 10, 2000
    Date of Patent: June 3, 2003
    Assignee: Novozymes, A/S
    Inventors: Niels Henrik Sorensen, Jason Patrick McDevitt
  • Patent number: 6511682
    Abstract: Described is a process of producing a concentrated liquid biocide formulation. Mixed together are (a) bromine chloride or bromine and (b) an aqueous solution of alkali metal salt of sulfamic acid having a pH of at least about 7, in amounts such that (i) the active bromine content of the solution is at least about 100,000 ppm (wt/wt), and (ii) the atom ratio of nitrogen to active bromine from (a) and (b) is greater than 1 when bromine is used and is greater than 0.93 when bromine chloride is used. Use of bromine chloride as the source of the active bromine in the process is preferred because in the resulting aqueous compositions, all of the bromine of the bromine chloride is made available as active bromine in solution. In other words, the chlorine of the bromine chloride is converted in the process to dissolved alkali metal chloride salt, thereby liberating all of the bromine in the biocidal composition as active bromine capable of providing biocidal activity.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: January 28, 2003
    Assignee: Albemarle Corporation
    Inventors: Robert M. Moore, Jr., Christopher J. Nalepa
  • Patent number: 6506737
    Abstract: An oxidizing species is described herein as a reaction product through an in situ preparation combining a protonizable phosphorus or sulfur compound, and a halide source at controlled proportions in an aqueous, non-aqueous, gel, aerosol, solid-phase or powdered media. The oxidizing species can be used to reduce microbial and viral populations on a surface or object or in a body or stream of water. The invention thus finds applications as a bleach, sanitizer, oxidant, or in any other application in which an oxidizing agent can be beneficially used alone or in a formulation.
    Type: Grant
    Filed: April 5, 2000
    Date of Patent: January 14, 2003
    Assignee: Ecolab, Inc.
    Inventors: Robert D. P. Hei, Kim Smith
  • Patent number: 6506416
    Abstract: The present invention provides a virucide composition and/or sporicide composition having a high virucidal effect and sporicidal effect and being excellent in safety and workability. That is, the present invention provides a virucide composition and/or sporicide composition comprising (a) an inorganic peroxide, (b) tetraacetylethylenediamine and (c) at least one selected from a salt of an alkaline metal salt with an inorganic acid and a salt of an alkaline earth metal with an inorganic acid in a specific ratio.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: January 14, 2003
    Assignee: Kao Corporation
    Inventors: Yuji Okauchi, Tadashi Moriyama, Hiroyoshi Hiramatsu, Yuichi Hioki
  • Patent number: 6506418
    Abstract: Concentrated liquid biocide compositions are produced by: A) feeding (a) bromine atoms and chlorine atoms in the form of (i) one or more of BrCl, (ii) Br2, and (iii) Cl2 into (b) water containing sulfamate anions, or feeding each of (a) and (b) into a reaction vessel, such that the numerical ratio of the total number of bromine atoms fed to the total number of chlorine atoms fed is in the range of about 0.7:1 to about 1.7:1; and B) providing enough alkali metal base in the mixture being formed in A) to keep the pH of such mixture in the range of about 7-11 during all or substantially all of the time feeding in A) is occurring, the amounts of (a) and (b) used being amounts that form an active-bromine-containing solution in which (i) the active bromine content is 50,000 ppm or more, and (ii) the atom ratio of nitrogen to active bromine originating from (a) and (b) is greater than about 0.
    Type: Grant
    Filed: December 7, 2000
    Date of Patent: January 14, 2003
    Assignee: Albemarle Corporation
    Inventors: Bonnie G. McKinnie, Alvin E. Harkins, Jr., Robert M. Moore, Jr.
  • Patent number: 6409992
    Abstract: The present invention relates to an oral composition containing a zinc compound containing free available zinc ion and at least one stabilized or stable Eh raising compound distributed in an oral vehicle. The present invention further relates to a method of inhibiting the formation of sulfur containing anions and preventing a reduction in the Eh of the oral cavity. A method of reducing oral malodor and gingivitis and periodontitis is also provided by this invention.
    Type: Grant
    Filed: June 10, 1998
    Date of Patent: June 25, 2002
    Assignee: The Research Foundation of State University of New York
    Inventors: Israel Kleinberg, Milroy Codipilly
  • Patent number: 6352725
    Abstract: The process involves (a) continuously forming bromine chloride from separate feed streams of bromine and chlorine by maintaining said streams under automatic feed rate control whereby the streams are continuously proportioned to come together in equimolar amounts to form bromine chloride; (b) continuously forming an aqueous product having an active bromine content of at least 100,000 ppm (wt/wt), a pH of at least 7, and an atom ratio of nitrogen to active bromine greater than 0.93:1 by continuously feeding into mixing apparatus separate feed streams of (1) bromine chloride formed in (a), and (2) an aqueous solution of alkali metal salt of sulfamic acid, under automatic feed rate control whereby the feed streams are continuously proportioned to come together in amounts that produce an aqueous product having an active bromine content of at least 100,000 ppm (wt/wt), a pH of at least 7, and an atom ratio of nitrogen to active bromine from (1) and (2) greater than 0.
    Type: Grant
    Filed: November 30, 1999
    Date of Patent: March 5, 2002
    Assignee: Albemarle Corporation
    Inventors: James E. Torres, Robert M. Moore, Jr., R. Woodrow Wilson, Jr., Gary D. Focht
  • Patent number: 6348219
    Abstract: The process involves (a) continuously forming bromine chloride from separate feed streams of bromine and chlorine by maintaining said streams under automatic feed rate control whereby the streams are continuously proportioned to come together to form bromine chloride; (b) continuously forming an aqueous product having an active bromine content of at least 100,000 ppm (wt/wt), a pH of at least 7, and an atom ratio of nitrogen to active bromine greater than 0.93:1 by continuously or intermittently feeding into mixing apparatus separate feed streams of (1) bromine chloride formed in (a), and (2) an aqueous solution of alkali metal salt of sulfamic acid, under automatic feed rate control.
    Type: Grant
    Filed: September 18, 2000
    Date of Patent: February 19, 2002
    Assignee: Albemarle Corporation
    Inventors: James E. Torres, Robert M. Moore, Jr., R. Woodrow Wilson, Jr., Gary D. Focht
  • Patent number: 6322822
    Abstract: Methods for disinfecting surfaces and for sanitizing bodies of water using a single-feed, bromine-based biocide are described. These methods use concentrated liquid biocide compositions comprising biocidally active bromine as the biocide. Also described is a process of producing the concentrated liquid biocide composition: mixed together are (a) bromine chloride and (b) an aqueous solution of alkali metal salt of sulfamic acid having a pH of at least about 7, in amounts such that (i) the active bromine content of the composition is at least about 100,000 ppm (wt/wt), and (ii) the atom ratio of nitrogen to active bromine in the composition is greater than 0.93. Use of bromine chloride as the source of the active bromine in the process is advantageous because in the resulting aqueous compositions, all of the bromine of the bromine chloride is made available as active bromine in solution.
    Type: Grant
    Filed: September 24, 1999
    Date of Patent: November 27, 2001
    Assignee: Albemarle Corporation
    Inventors: Robert M. Moore, Jr., Christopher J. Nalepa
  • Patent number: 6306441
    Abstract: A concentrated liquid biocide composition is produced by a continuous process. The process comprises continuously feeding into mixing apparatus (i) bromine chloride and (ii) an aqueous solution of alkali metal salt of sulfamic acid. These are proportioned to produce an aqueous product having an active bromine content of at least 100,000 ppm (wt/wt), and an atom ratio of nitrogen to active bromine from (i) and (ii) greater than 0.93:1. The desired product is withdrawn from the mixing apparatus at a rate sufficient to enable the continuous feeding to be maintained. Thus, the withdrawal of the product can be continuous or intermittent, depending upon the type of mixing apparatus being used.
    Type: Grant
    Filed: November 17, 1999
    Date of Patent: October 23, 2001
    Assignee: Albemarle Corporation
    Inventors: Robert M. Moore, Jr., R. Woodrow Wilson, Jr.
  • Patent number: 6299909
    Abstract: A concentrated liquid biocide composition is produced by a process which comprises continuously or intermittently feeding (i) bromine chloride into mixing apparatus where the bromine chloride contacts (ii) an aqueous solution of alkali metal salt of sulfamic acid. An aqueous product is produced having an active bromine content of at least 100,000 ppm (wt/wt), and an atom ratio of nitrogen to active bromine from (i) and (ii) greater than 0.93:1. The desired product can be withdrawn from the mixing apparatus continuously or intermittently.
    Type: Grant
    Filed: September 18, 2000
    Date of Patent: October 9, 2001
    Assignee: Albemarle Corporation
    Inventors: Robert M. Moore, Jr., R. Woodrow Wilson, Jr.
  • Patent number: 6280775
    Abstract: This invention provides a liquid antimicrobial composition that is particularly useful as a mouthwash for treating or reducing the risk of dental disease. The composition is prepared by mixing a first solution comprising a water soluble metal chlorite compound with a second solution comprising sodium persulfate and hydrogen peroxide. The resulting composition, containing chlorine dioxide, is preferably used at the time of preparation by applying the composition to the locus where treatment is desired.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: August 28, 2001
    Inventors: Joseph Alan Sasson, Riccardo Panicucci
  • Patent number: 6277414
    Abstract: The present invention relates to an aqueous decontaminating composition comprising (A) an amount of H2O2 less than or equal to 60% by weight, based on the total weight of said composition; (B) an RCO3H/RCO2H mixture, where R is methyl or ethyl, as indicated above, said mixture being present in an amount such that the weight ratio of said mixture to the hydrogen peroxide is between 0.15/1 and 0.85/1; (C) a silver component as a source of Ag ions, selected from the group consisting of silver salts and complexes, said silver component being present in an amount such that the weight ratio of said silver component to the hydrogen peroxide is between 0.0005/1 and 0.015/1; (D) a stabilizer present in an amount such that the weight ratio of said stabilizer to the hydrogen peroxide is between 0.0005/1 and 0.025/1; and water to make up to 100% by weight. It further relates to the method of preparation and to the use of said composition.
    Type: Grant
    Filed: September 22, 1998
    Date of Patent: August 21, 2001
    Assignee: Sodifra
    Inventors: Alain Elhaik, Raphaël Alex De Nicola
  • Publication number: 20010009664
    Abstract: An enzymatic antimicrobial composition comprising a haloperoxidase, a hydrogen peroxide source, a halide source, and an ammonium source, in particular an ammonium salt or an aminoalcohol, in which there is a hitherto unknown synergistic effect between the halide and the ammonium source.
    Type: Application
    Filed: January 24, 2001
    Publication date: July 26, 2001
    Applicant: Novozymes A/S
    Inventor: Charlotte Johansen
  • Patent number: 6231848
    Abstract: The present invention relates to topical products intended for use as prophylactic or curative agents for bacterial skin infections, containing at least one polymeric complex substantially consisting of hydrogen peroxide, a suitable polymer for the complex formation thereof, possibly another bactericidal compound and possibly a metal salt or a metal colloid.
    Type: Grant
    Filed: March 25, 1999
    Date of Patent: May 15, 2001
    Assignee: BASF Aktiengesellschaft
    Inventors: Jörg Breitenbach, Bernhard Fussnegger, Siegfried Lang
  • Patent number: 6211213
    Abstract: Stable microbicidal compositions containing a 3-isothiazolone compound, organic oxidants, copper salts and water are disclosed. Also disclosed are methods of stabilizing 3-isothiazolone compositions.
    Type: Grant
    Filed: April 12, 2000
    Date of Patent: April 3, 2001
    Assignee: Rohm and Haas Company
    Inventor: Beverly Jean El A'mma
  • Patent number: 6068861
    Abstract: Described is a process of producing a concentrated liquid biocide formulation. Mixed together are (a) bromine chloride or bromine and (b) an aqueous solution of alkali metal salt of sulfamic acid having a pH of at least about 7, in amounts such that (i) the active bromine content of the solution is at least about 100,000 ppm (wt/wt), and (ii) the atom ratio of nitrogen to active bromine from (a) and (b) is greater than 1 when bromine is used and is greater than 0.93 when bromine chloride is used. Use of bromine chloride as the source of the active bromine in the process is preferred because in the resulting aqueous compositions, all of the bromine of the bromine chloride is made available as active bromine in solution. In other words, the chlorine of the bromine chloride is converted in the process to dissolved alkali metal chloride salt, thereby liberating all of the bromine as the active bromine content of the biocidal composition.
    Type: Grant
    Filed: June 1, 1998
    Date of Patent: May 30, 2000
    Assignee: Albemarle Corporation
    Inventors: Robert M. Moore, Jr., Christopher J. Nalepa
  • Patent number: 5958463
    Abstract: The present invention relates generally to the method for the production of liposomal microencapsulated boron-containing products to be used for agricultural formulations. More specifically, a new method of production of liposomal microencapsulated is disclosed for active agents such as pesticides. A lecithin is mixed with an organic solvent in a certain proportion so as to provide solutions with varied levels of solubilized lecithin. The particular solvent being used will depend on the amount of active agent (AA) desired in the final solution. The formulation of the lecithin/organic solvent mixture is then allowed to settle. After settling, the top layer is separated and saved, while the bottom layer is discarded. An AA is then added to form a concentrate that is added to water for vesicle formation. Boron-containing materials formulated according to the invention may now be applied to agricultural field crops and fruits.
    Type: Grant
    Filed: November 22, 1996
    Date of Patent: September 28, 1999
    Assignee: Agri-Tek, Inc.
    Inventors: Christopher G. Milne, Paulus P. Shelby, Jr.
  • Patent number: 5827542
    Abstract: A low odor, aqueous, quick acting room temperature disinfectant solution primarily useful for medical instruments to disinfect within a half hour or less. The composition comprises a reacting or synergistic combination of hydrogen peroxide and from about 1% to 30% by weight of a water soluble organic acid or salt form thereof with the acid preferably being selected from the group consisting of malonic and succinic acids.
    Type: Grant
    Filed: February 12, 1996
    Date of Patent: October 27, 1998
    Assignee: Healthpoint, Ltd.
    Inventors: Norman A. Miner, William H. Woller, Edward L. Anderson, David W Hobson
  • Patent number: 5770232
    Abstract: A method of disinfecting the food contact surfaces of a food packaging machine comprises introducing to the machine an aqueous solution comprising from about 0.1% to about 1% by weight of hydrogen peroxide and from about 0.01% to about 0.1% by weight of sodium acid pyrophosphate. The food contact surfaces are contacted with the solution at a temperature of at least about 70.degree. C. for a time period of at least about 15 minutes.
    Type: Grant
    Filed: March 3, 1997
    Date of Patent: June 23, 1998
    Assignee: Tetra Laval Holdings & Finance, SA
    Inventors: Charles S. Sizer, Ronald W. Swank
  • Patent number: 5736165
    Abstract: Disclosed are in-the-eye uses of chlorine dioxide-containing compositions as effective ophthalmic antiseptics and as effective ophthalmic surgical irrigants. Surprisingly low concentrations of chlorine dioxide are effective in such applications. In addition, the presently useful compositions are ophthalmically acceptable.
    Type: Grant
    Filed: July 20, 1994
    Date of Patent: April 7, 1998
    Assignee: Allergan
    Inventors: Paul S. Ripley, Anthony J. Dziabo, Claude B. Anger
  • Patent number: 5723140
    Abstract: A method for treating an individual to prevent the occurrence of pressure ulcers and facilitate the healing of previously existing pressure ulcers. In accordance with the present invention, a responsible individual must first determine which linens will contact pressure points on the individual as the individual lies upon a support surface. Once the appropriate linens are determined, they are prepared by cleaning the linens in ozonated wash water to limit chemical residuals and maintain neutral pH levels on the linens, wherein the linens exhibiting no chemical residuals and neutral pH cause no chemical reaction with the skin of the individual. Finally, the linens are placed into use so that they contact the skin of the individual at pressure points.
    Type: Grant
    Filed: January 30, 1996
    Date of Patent: March 3, 1998
    Inventors: Charles W. Pearsall, Manuel Caldera
  • Patent number: 5639445
    Abstract: A dental composition is produced from a dilatant silicone polymer composition by dispersing a bioactive component in the polymer composition. The dental composition is shaped and pressed against the teeth and gum surfaces and allowed to remain in place for a period of time sufficient to release the active component to the tooth and gums. The dilatant rheological properties enable the dental composition to be pushed under the gingival flap to remove food particles and treat tooth and gum surfaces below the gum line. The composition is sufficiently plastic to be easily removed from the teeth without pieces breaking and adhering to tooth surfaces.
    Type: Grant
    Filed: January 6, 1994
    Date of Patent: June 17, 1997
    Assignee: Colgate-Palmolive Company
    Inventors: John Curtis, Salim Nathoo, Michael Prencipe
  • Patent number: 5632972
    Abstract: A method for minimizing damage to gingival and periodontal tissue is provided through steps that include delivering a first composition containing a zinc salt to a receptacle, delivering a second composition containing a bicarbonate salt to the same receptacle, and transferring within five minutes of delivery to the receptacle the combination into the mouth onto the gingival and periodontal tissues. Where the compositions are semi-solid such as in a toothpaste and/or gel, the receptacle is ordinarily a toothbrush. Liquid compositions such as mouthrinses may employ an expectorant cup as a receptacle.
    Type: Grant
    Filed: June 30, 1994
    Date of Patent: May 27, 1997
    Assignee: Chesebrough-Pond's USA Co., Division of Conopco, Inc.
    Inventors: David R. Williams, Christine W. Ryles, Stephen R. Barrow
  • Patent number: 5616347
    Abstract: The present invention relates to the discovery that the inclusion of effective amounts of an irritation reducing compound selected from the group consisting of allantoin, glycerine, aloe vera and mixtures, thereof, in a chlorine dioxide generating composition will substantially reduce skin irritation which is caused by chlorine dioxide exposure to the skin.
    Type: Grant
    Filed: February 14, 1995
    Date of Patent: April 1, 1997
    Inventors: Howard Alliger, Habib Roozdar
  • Patent number: 5616313
    Abstract: A method for minimizing damage to gingival and periodontal tissue is provided through steps that include delivering a first composition containing a zinc salt to a receptacle, delivering a second composition containing a bicarbonate salt to the same receptacle, and transferring within five minutes of delivery to the receptacle the combination into the mouth onto the gingival and periodontal tissues. Where the compositions are semi-solid such as in a toothpaste and/or gel, the receptacle is ordinarily a toothbrush. Liquid compositions such as mouthrinses may employ an expectorant cup as a receptacle.
    Type: Grant
    Filed: April 11, 1995
    Date of Patent: April 1, 1997
    Assignee: Chesebrough-Pond's USA Co., Division of Conopco, Inc.
    Inventors: David R. Williams, Christine W. Ryles, Stephen R. Barrow
  • Patent number: 5599527
    Abstract: A storage stable oral composition which is effective against calculus which contains an orally acceptable vehicle having incorporated therein an effective anticalculus combination of about 0.5 to about 2% by weight of a water soluble pyrophosphate salt and about 0.5 to about 3% by weight of a water soluble polyphosphate salt. The presence in the composition of polyvalent metal compounds and fluoride compounds do not affect the stability of the composition as well as reactive ingredients such as peroxide and bicarbonate compounds.
    Type: Grant
    Filed: November 14, 1994
    Date of Patent: February 4, 1997
    Assignee: Colgate-Palmolive Company
    Inventors: Donald P. Hsu, Rajnish Kohli, Michael Prencipe
  • Patent number: 5472694
    Abstract: The present invention relates to a method for manufacturing tea by treating the leaves of cyclobalanopsis stenophylla. The leaves of cyclobalanopsis stenophylla are collected in May or June and, directly thereafter, are treated with steam for 50.+-.10 minutes. When their green color changes into a yellowish brown and a savory smell is given out, they are taken out and desiccated in the shade and, then, based on volume, 5% to 10% of glutinous rice or polished glutinous millet is mixed in 90% to 95% of water and put in the bottom of a steamer. A bored plate is placed on the steamer, and the desiccated leaves are put down on the plate and treated for 20.+-.5 minutes with steam generated by applying heat to the steamer and the leaves treated with steam are desiccated again and made into tea.
    Type: Grant
    Filed: October 20, 1993
    Date of Patent: December 5, 1995
    Inventors: Han Y. Chae, Baek H. Sik
  • Patent number: 5468737
    Abstract: A method for promoting wound healing involving initiating and accelerating wound repair and tissue regeneration in an animal by systemic administration of a bioactive polysaccharide derived from aloe vera plant.
    Type: Grant
    Filed: April 7, 1994
    Date of Patent: November 21, 1995
    Assignee: Carrington Laboratories, Inc.
    Inventors: Bill H. McAnalley, Robert H. Carpenter, Harley R. McDaniel
  • Patent number: 5310563
    Abstract: A dental composition is produced from a dilatant silicone polymer composition by dispersing a bioactive component in the polymer composition. The dental composition is shaped and pressed against the teeth and gum surfaces and allowed to remain in place for a period of time sufficient to release the active component to the tooth and gums. The dilatant rheological properties enable the dental composition to be pushed under the gingival flap to remove food particles and treat tooth and gum surfaces below the gum line. The composition is sufficiently plastic to be easily removed from the teeth without pieces breaking and adhering to tooth surfaces.
    Type: Grant
    Filed: October 25, 1991
    Date of Patent: May 10, 1994
    Assignee: Colgate-Palmolive Company
    Inventors: John Curtis, Salim Nahoo, Michael Prencipe
  • Patent number: 5256423
    Abstract: A method for destroying cyst of noxious plankton, which comprises mixing in ballast water hydrogen peroxide or a compound producing the same and maintaining an effective concentration thereof for destroying cyst of noxious plankton.
    Type: Grant
    Filed: October 4, 1991
    Date of Patent: October 26, 1993
    Assignee: Katayama Chemical, Inc.
    Inventors: Syuzo Egusa, Yasuo Fukuyo
  • Patent number: 5171564
    Abstract: An aqueous abrasive oral composition which exhibits heightened and rapid whitening of teeth is obtained when using a combination of a dicalcium phosphate compound, a metal ion free peroxide, a chelating agent and a thickening agent.
    Type: Grant
    Filed: September 13, 1991
    Date of Patent: December 15, 1992
    Assignee: Colgate-Palmolive
    Inventors: Salim A. Nathoo, Mary B. Chmielewski, Sahar Fakhry-Smith
  • Patent number: 5118401
    Abstract: Apparatus for applying a disinfectant solution which may include hydrogen peroxide, a salt and a buffer to an instrument wherein the instrument can be inserted into an opening in the wall of a vessel containing a disinfectant normally at a level below the opening. A floatation plunger is urged downwardly to displace the disinfectant to a level in engagement with the instrument and the electrodes are energized to activate the disinfectant. A magnetic latch holds the floatation plunger in place during disinfection and the disinfectant level is sensed to enable energization of the electrodes only when the level is sufficient to engage the instrument.
    Type: Grant
    Filed: June 4, 1990
    Date of Patent: June 2, 1992
    Inventors: Henry C. Oksman, Joseph Eisner
  • Patent number: 4988500
    Abstract: Anhydrous oral compositions are disclosed containing an anhydrous humectant and a carboxyvinyl polymer neutralized with an appropriate base.
    Type: Grant
    Filed: September 29, 1989
    Date of Patent: January 29, 1991
    Assignee: The Procter & Gamble Company
    Inventors: Mary A. Hunter, Joseph W. Pyrz
  • Patent number: 4937072
    Abstract: The method comprises forming a sporocide having a defined period of sporocidal activity comprising three components including a peroxide or peroxide generating material, a peroxidase and a salt of iodide which serves as a donor molecule; storing the three components in a nonreacting state to maintain the sporocide in an inactive state and admixing the three components in a aqueous based carrier to cause a catalyzed reaction by said peroxidase for generating free radicals and/or byproducts from the iodide salt (donor molecule) and contacting the surface or object to be sterilized with the activated mixture. The concentration level of the three components can be selected such that an active sporocidal state is maintained for any desired period of time.
    Type: Grant
    Filed: November 7, 1988
    Date of Patent: June 26, 1990
    Inventors: Jack H. Kessler, Robert S. Rosenbaum