Abstract: The invention relates to an antimicrobial layer material comprising a layer with a particulate biocidal active ingredient and, on top of that, a layer as transport control layer, wherein the transport control layer is depositable or has been deposited in an afterglow PE-CVD method. The invention further relates to a substrate coated with such an antimicrobial layer material, to the use of a plasma-polymeric layer deposited in an afterglow PE-CVD method as transport control layer for a particulate biocidal active ingredient, and to a method of producing an antimicrobial layer material and to a method of producing a substrate comprising an antimicrobial layer material.

Abstract: An object of the present invention is to provide a novel composition for promoting ketone body production. The present invention provides a composition for use in promoting ketone body production, comprising one or more amino acid(s) selected from the group consisting of citrulline, leucine, cysteine, taurine, glutamine, and aspartic acid. The composition according to the present invention may further comprise either or both of a medium-chain fatty acid and a medium-chain fatty acid ester.

Abstract: A single-use suppository insertion device includes a barrel, a plunger configured to be movably coupled to the barrel, and a disabling feature of the barrel or the plunger. The disabling feature may be configured to be activated during operational motion of the plunger relative to the barrel, such as during insertion of or withdrawal away from a suppository. The device can include a structural element of the barrel or the plunger configured to engage with the disabling feature of the barrel or the plunger during insertion of or withdrawal away from the suppository to activate the disabling feature. The disabling feature may be implemented in a number of ways to ensure single-use operation of the single-use suppository insertion device.

Abstract: A method of treating a wound may include topically administering a statin composition including a statin selected from atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin, or combination thereof. The statin composition may be administered in an ointment, powder, or liquid format. The method may also include topically administering one or more antimicrobial drugs and/or naltrexone.

Abstract: A filtering material for air filters, the filtering material including a base material; and an enzyme-containing antibacterial material, an inorganic anti-allergenic material, and a fungal inhibitor, all being supported on the base material.

Abstract: A disinfectant composition that is capable of inactivating non-enveloped viruses as well as other microorganisms, such as gram negative and gram positive bacteria, fungi, parasites, enveloped viruses, etc., is provided. Through selective control over the nature of the acid(s) employed and the overall pH level, the present inventors have discovered that the composition can achieve rapid antiviral efficacy, particularly against non-enveloped viruses. Once applied to a surface (e.g., hard surface), the disinfectant composition forms a film that remains capable of providing residual antiviral activity. Notably, the present inventors have discovered that the use of a vinylpyrrolidone copolymer in combination with a polyquaternary ammonium polymer and cationic surfactant can have a synergistic effect on the stability of the film such that it can also achieve long-term, residual antiviral activity.

Abstract: An antimicrobial composition comprising (i) an effective amount of a first antimicrobial agent consisting of at least one compound according to Formula 1: wherein R1 is a branched or unbranched, saturated or unsaturated, unsubstituted C3 to C5 alkyl chain or a C3 alkyl chain substituted with a methoxy group; (ii) (optionally) an effective amount of at least one surfactant selected from the group consisting of anionic surfactants, nonionic surfactants, amphoteric surfactants, and cationic surfactants; and (iii) a diluent, q.s. to 100; wherein the antimicrobial composition is substantially free of peroxygen compounds, antibiotics, and chloroacetamide. Also described are methods of using the composition in the field of infection control and prevention.

Abstract: Antioxidant composition for increasing the levels of vitamins and reducing oxidative damage in a subject; the composition comprises an active agent, containing polydatin and acetylcysteine.

Abstract: Embodiments of the present disclosure, in one aspect, relate to compositions including a vacancy-engineered (VE)-ZnO nanocomposite, methods of making a composition, methods of using a composition, and the like.

Abstract: An apparatus includes a substrate having a surface, and a transparent semiconductor photocatalyst layer secured to the surface of the substrate, wherein the photocatalyst layer includes titanium oxide and a component selected from a fluorescent dye, ultra-fine glitter, indium tin oxide, aluminum zinc oxide, silver nitrate, and combinations thereof. The photocatalyst coating may be formed on a substrate using a formulation that includes an aqueous mixture of titanium oxide and amorphous titanium peroxide, wherein the aqueous mixture may further include one of the components. A method of forming the photocatalyst coating may include applying an aqueous mixture of titanium oxide and amorphous titanium peroxide to a surface of the substrate, wherein the photocatalyst coating includes a fluorescent dye, ultra-fine glitter, indium tin oxide, aluminum zinc oxide, and/or silver nitrate. The aqueous mixture may then be dried and heated to 100 degrees Celsius or greater.

Abstract: The present invention is directed to a pesticidal composition comprising clothianidin, a graft copolymer, an acrylic (type) co-polymer having a backbone containing a carboxylated ethylenically unsaturated monomer and a non-carboxylated ethylenically unsaturated monomer and optionally, a poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymer having an average molecular weight from about 4950 to about 6500 and a hydrophile weight percentage from about 30% to about 50%. The present invention is further directed to a method of controlling a pest comprising applying a composition of the present invention to an area in need of pest control.

Abstract: The present invention relates to an antimicrobial composition comprising a grape extract, a lemon extract, and a lavender extract. Not only providing excellent antiviral, antibacterial, and antifungal effects but also being derived from natural products, the composition of the present invention can be used safely without toxicity and side effects and can find various applications in medicinal products, foods, cosmetic products, quasi-drugs, etc.

Abstract: A method of extracting active ingredients in mushrooms includes following steps: crushing a mushroom to obtain a crude mushroom crush; mixing the crude mushroom crush with deionized water to obtain a crude crush mixture; adding the crude crush mixture into a subcritical fluid extractor and extracting the crude crush mixture to obtain a crude mushroom extract; centrifuging the crude mushroom extract to harvest a first supernatant and a mushroom residue; mixing the mushroom residue with deionized water and a cellulase enzyme to obtain a reaction mixture; adding the reaction mixture into a high-pressure hydrolysis reactor and extracting the reaction mixture to obtain a hydrolysate; centrifuging the hydrolysate to obtain a second supernatant; and combining the first supernatant and the second supernatant, and then concentrating the combined first and second supernatants to obtain a mushroom extraction solution.

Abstract: Provided is a textile made of filament yarn comprising a polymer composition that is durable and reusable having permanent or near-permanent antiviral properties and that includes a polymer, a metal ion, preferably a zinc and/or copper ion, and an optional phosphorus compound, wherein fibers and/or fabric formed from the polymer composition demonstrate antiviral properties and wherein the polymer is hygroscopic. The present disclosure also describes methods of forming the polymer compositions and methods of preparing fibers from the polymer composition.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating diabetes, comprising, as active ingredients: (a) a zinc salt, comprising a zinc cation and anion, and cyclo-hispro, or a pharmaceutically acceptable salt thereof; and (b) an antidiabetic drug (particularly, an insulin sensitizer, an insulin sensitizer, a sodium-glucose co-transporter (a sodium-glucose co-transporter 2 (SGLT2) inhibitor), or a DPP-4 inhibitor).

Abstract: Compositions and methods for treating and preventing respiratory symptoms related to viral and bacterial infections are described. The composition includes water, ionic minerals, trace minerals, a niacin-related compound, and an optional ingredient. The optional ingredient is mastic gum, a prebiotic, or both. The niacin-related compound is methyl nicotinate, nicotinic acid, nicotinamide, niacin, or a combination of two or more of the foregoing. The method involves nasal, auricular, or oral administration or a combination of two or more of the foregoing routes of administration to a human or other mammal.

Abstract: The present invention relates to compositions, in particular dietary compositions, that comprise a combination of choline cation and succinate anion (2?) and nicotinamide, and use of these compositions for maintaining and enhancing the brain energy metabolism in a human, and for preventing and treating symptoms and physiological conditions associated with an imbalanced, damaged or slowed brain energy metabolism in a human subject.

Abstract: The present application discloses a semiconductor device with a barrier layer including aluminum fluoride and a method for fabricating the semiconductor device. The semiconductor device includes a substrate, a circuit layer positioned on the substrate, a pad layer positioned in the circuit layer and including aluminum and copper, a first barrier layer positioned on the pad layer and including aluminum fluoride, and a first connector positioned on the first barrier layer.

Abstract: A weight loss composition including banaba leaf extract, apple fruit extract, Rhodiola root extract, zinc chelate, and magnesium chelate are described. The weight loss composition may further include gardenia fruit extract, chromium chelate, Salacia extract, berberine, inositol, or mixtures thereof. Embodiments are also directed to a bulk food product and a weight management plan, which may be used in conjunction with the weight loss composition. Embodiments are also directed to kits and methods of use for treating or preventing obesity, promoting weight loss, and improving insulin resistance.

Abstract: Surgical stapling apparatuses have a surgical buttress attached thereto. The surgical buttress includes an elongate rectangular body having a proximal portion, a distal portion, and opposing lateral sides running along the elongate rectangular body from the proximal portion to the distal portion. Magnesium is on a surface and/or in pores of the surgical buttress.

Abstract: This invention is directed to methods for prevention of infections by highly pathogenic viruses by applying to the nasal mucous membranes topical preparations comprising the broad-spectrum antimicrobial agent povidone-iodine.

Abstract: The present invention provides for novel combinations comprising an antihistamine with selected pharmaceutical and nutraceutical agents which alleviate some of the symptoms experienced by menopausal women, optionally combined further with a range of indole-based natural products such as L-tryptophan, 5-hydroxytryptophan and melatonin. These mixtures may be enriched further with pharmaceutically acceptable calcium and magnesium salts as well as selected B vitamins. These combinations have utility in providing a medicament for improving health in mammals, especially for the improvement of menopausal symptoms as welt as sleep in women.

Abstract: Provided is a method for determining whether or not infection with Bursaphelenchus xylophilus exists. The method includes a first sap extraction step of immersing a first fragment sample taken from a first tree in a solvent to extract a first sap contained in the first fragment sample of the first tree, a first concentration analysis step of analyzing a first concentration of an organic compound contained in the first sap, and a first comparison step of comparing the first concentration with a reference concentration of the organic compound contained in the sap of a tree that has not been infected with Bursaphelenchus xylophilus, so as to determine whether or not a coniferous tree is infected with Bursaphelenchus xylophilus.

Abstract: The invention describes a combination of at least one aromatase inhibitor selected from the group of chemical-synthetic aromatase inhibitors and aromatase inhibition exhibiting extracts of soya beans and rapeseed, respectively, and at least one plant extract that contains one or more active ingredient substance(s) extracted from the plant, which is(are) selected from the group of 5? reductase type I and/or type II inhibitors and androgen receptor blockers, said combination being contained for example in a composition and having special properties for influencing hair growth. Uses of this combination are also described.

Abstract: A composition comprising one or more polyphenols, such as oleuropein, rutin, curcumin or quercetin, can treat or prevent sarcopenia, reduce a loss of muscle functionality (e.g. muscle strength, gait speed, etc.), increase muscle functionality, and/or improve recovery of muscle functionality after muscle atrophy. The composition can be administered to an individual who is elderly and/or frail.

Abstract: A composition contains curcumin and can treat or prevent sarcopenia, reduce a loss of muscle functionality (e.g. muscle strength, gait speed, etc.), increase muscle functionality, and/or improve recovery of muscle functionality after muscle atrophy. The composition can be administered to an individual who is elderly and/or frail, optionally in a composition that further includes an omega-3 fatty acid and/or a protein source.

Abstract: Provided are a pharmaceutical composition for wound healing including a surfactant, an antioxidant, a thickener, and SP, a method of treating a wound including administering the pharmaceutical composition to a subject, and a quasi-drug composition for wound healing including a surfactant, an antioxidant, a thickener, and substance. The pharmaceutical composition of the present invention reduces a wound size, generates new blood vessels, shows dermal and epidermal regeneration effects, matures granulation tissues, and synthesizes collagen, and thus may be used for wound healing.

Abstract: Disclosed herein are methods of treating disease with a combination of a RXR agonist and a thyroid hormone.

Abstract: The present invention provides a computer program for determining the optimum diet of an animal, determining what nutritional deficiencies exist in that diet, and formulating a supplement to correct those deficiencies. It allows the creation of a nutritionally complete and balanced diet with a sufficient but not excessive quantity of water, energy, protein, fat, carbohydrate, amino acids, fatty acids, vitamins, minerals, and vitamin-like nutrients. The specific compositions of supplements generated using the computer program are also claimed.

Abstract: The invention pertains to methods of treating alloys, particularly, biodegradable alloys containing Mg, Zn or Fe. The alloys can be treated with at least one of the following procedures: mechanical polishing, anodization, and polymer coating. Advantageously, methods provided herein enhance the anti-thrombogenicity of the alloy surface. Such materials can be used for preparing biomedical devices, such as endovascular implants, vascular implants, drug-eluting stents, orthopedic prostheses, or implantable chips. Methods of treating a subject by implanting the biomedical devices into the subject are also provided.

Abstract: The invention relates to a dialysis formulation, optionally a citrate containing dialysis formulation, comprising selenium (Se), optionally in combination with further trace elements selected from rubidium (Rb), cobalt (Co), molybdenum (Mo), and zinc (Zn). The dialysis formulation is intended to be used in dialysis treatment.

Abstract: A profertility composition for administration to infertile men with sperm oxidative stress is disclosed. The composition comprises a unique combination of a pharmaceutically acceptable vitamin E, vitamin C, selenium, zinc, folic acid, lycopene and at least one carnitine source.

Abstract: The invention relates to agents for the control of parasites on animals, comprising an active substance from the group of the phenylpyrazoles and vitamin E or a derivative thereof, such as particularly vitamin E acetate, as well as optionally a further active substance from the group of the pyrethroids and/or optionally additionally further active and/or auxiliary substances. In particular, the invention relates to the use of such agents for the control of ectoparasites such as, in particular, fleas, ticks and sand flies in pets such as, in particular, in dogs, cats and ferrets.

Abstract: A dietary supplement composition includes a synergistic combination of saffron and resveratrol for providing anti-oxidant and gene modulation effects for preventing, ameliorating and/or reducing a rate of development and progression of age-related macular degeneration (AMD). Optionally, the combination is supplemented with one or more further ingredients: fish oil, Zinc, Copper, vitamin C, vitamin E, lutein, zeaxanthin. The combination is beneficially provided as a composition which is useful for reducing a risk of developing, and/or for reducing a rate of progression of age-related macular degeneration, and/or for preventing age-related sight loss, and other age-related diseases.

Abstract: Regimen for the treatment of rosacea include the application of an anti-redness composition to at least a portion of the cleansed area of skin afflicted with rosacea. The regimen may include the application of one or more of a polymetal complex, a composition containing metronidazole, and/or a protective composition. Kits containing components useful in performing such regimens are also described.

Abstract: The present invention relates to nutritional supplements that provide an adult with essential vitamins and minerals that may be lacking in the adult's diet and prevent chronic diseases, such as osteoporosis. A number of combinations of nutrients in set ratios are provided to increase the body's ability to absorb and use the nutrients. These combinations are important in helping the body reach the proper balance required for maximized function. Because adults over the age of 50 years have different nutritional needs, nutritional supplements specifically designed for them are also provided.

Abstract: The present invention provides an aqueous ophthalmic composition containing (A) a terpenoid, (B) zinc chloride, and (C) at least one member selected from the group consisting of cellulose-based polymeric compounds, vinyl-based polymeric compounds, polyethylene glycols and dextran. According to the present invention, an aqueous ophthalmic composition is provided in which adsorption of the terpenoid to a container can be inhibited, thereby making it possible to inhibit the reduction in the terpenoid content for a long period of time, the aqueous ophthalmic composition having some excellent actions such as an inhibitory action for histamine release, and an inhibitory action for discharges from the eyes.

Abstract: The present invention discloses a non-irritating tea tree oil (TTO)-based topical therapeutic composition useful for both veterinary and human dermatology. The composition comprises a homogeneous mixture of TTO, 0.05 to 1.0% (wt/wt); at least one hypertonic composition providing the said TTO-based composition to 1700 to 2500 mOsm/L, 10 to 60% (wt/wt); and inorganic salts, 0.01% to 0.50% (wt/wt) and it is characterized by an effective, rapid & wide spectrum of action while being non-irritant to patient skin.

Abstract: This invention relates to methods for administering an effective amount of a dietary or nutritional supplement composition that effectively changes the quality of the meibum lipid composition of inflamed or dysfunctional meibomian glands so as to improve or increase tear break up time, reduce tear osmolarity, and elevate the omega-3 index, while reducing or eliminating the symptoms associated with dry eye or meibomianitis. The dietary or nutritional supplement composition administered to the patient suffering from inflamed or dysfunctional meibomian glands comprises an effective amount of omega-3 fatty acids.

Abstract: Compositions and methods for modifying the composition of tight junction complexes and/or improving epithelial barrier function are disclosed.

Abstract: Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.

Abstract: The present invention is directed to nutritional and nutraceutical compositions which comprise novel mixtures of two or more indole-based dietary supplements such as L-tryptophan and melatonin, together with selected minerals and vitamins that stimulate tryptophan metabolism in the direction of serotonin and melatonin, and to their use in a preferred embodiment of the invention in a readily ingested beverage form, optionally combined with a range of other natural ingredients designed to improve the health and state of mind of human subjects. Alternative dosage forms, such as tablets for oral dosing, and dosage forms for buccal and sublingual administration, including thin films, are also incorporated in the present invention. Health improvements include the treatment of disorders of circadian rhythm, such as shift work disorder and jet lag, the induction of relaxation and a restful frame of mind, as well as providing restorative sleep function.

Abstract: The present invention provides a method of protecting wood or other celiulosic material from decay by copper-tolerant fungi, and wood preservative formulations for use in the same. The wood preservative formulations comprise a biocidal metal compound, a 1,2,4-triazole and a didecyl quaternary ammonium cation. Didecyldimethyl quaternary ammonium compounds are particularly preferred.

Abstract: A treatment protocol for use in the treatment of neurocutaneous syndrome is described and comprises at least one xanthone component, which may comprise at least one mangosteen component, and at least one detoxification component. Additional embodiments comprise at least one herbal component, at least one vitamin component, or a combination thereof. A method of treating a patient having neurocutaneous syndrome is described herein and comprises: providing at least one xanthone component, which may comprise at least one mangosteen component, providing at least one xanthone component, which may comprise at least one mangosteen component, to the patient, and administering the at least one detoxification component to the patient. Additional methods steps may include providing and administering at least one herbal component, providing and administering at least one vitamin component or a combination thereof.

Abstract: Bioabsorbable substrates having antimicrobial metal ion coatings that are well suited for implantation in to a subject's body to treat and/or prevent infection. In particular, described herein are flexible bioabsorbable filaments that are coated with an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, niobium or rhenium) on the filament so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is inserted into a subject's body. The anodic metal may be at least about 30 percent by volume of the coating.

Abstract: A lotion composition is provided. The lotion composition can comprise a) about 0.1% to about 90%, by weight, of a microcrystalline wax; b) about 0.1% to about 25%, by weight, of POE-4 monolaurate; c) about 0.1% to about 50%, by weight, of POE-8 monostearate; and d) a carrier.

Abstract: Methods are provided for reducing copper values for, by way of example, treating, preventing or ameliorating tissue damage such as, for example, tissue damage that may be caused by (i) disorders of the heart muscle (for example, cardiomyopathy or myocarditis) such as idiopathic cardiomyopathy, metabolic cardiomyopathy which includes diabetic cardiomyopathy, alcoholic cardiomyopathy, drug-induced cardiomyopathy, ischemic cardiomyopathy, and hypertensive cardiomyopathy, (ii) atheromatous disorders of the major blood vessels (macrovascular disease) such as the aorta, the coronary arteries, the carotid arteries, the cerebrovascular arteries, the renal arteries, the iliac arteries, the femoral arteries, and the popliteal arteries, (iii) drug induced, and metabolic (including hypertensive and/or diabetic disorders of small blood vessels (microvascular disease) such as the retinal arterioles, the glomerular arterioles, the vasa nervorum, cardiac arterioles, and associated capillary beds of the eye, the kidney, the h

Abstract: The present invention relates to a method and nutritional supplement which stimulates appetite and slows metabolism of a mammal, thereby enhancing weight gain for the mammal. The method of enhancing weight gain of the mammal comprises administering to the mammal an effective amount of at least two types of alkamide or isobutylamide compound extracted from Echinacea species along with an antioxidant and optionally minerals. The nutritional supplement of the present invention comprises an antioxidant and at least two types of alkamide or isobutylamide compounds derived from Echinacea species. Minerals such as zinc and magnesium can also be added to the nutritional supplement to provide even better effect.

Abstract: Bioactive porous bone graft implants in various forms suitable for use in bone tissue regeneration and/or repair, as well as methods of use are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may be contained in polymer for enhanced clinical results and better handling.

Abstract: This Invention Patent application consists of a fabric to be used in textile applications, which makes those items more comfortable and increases their bactericidal capacity, both in the number of types that it fights, and in the time that this capacity is effective, using a mixture of fibres and performing a series of treatments prior to the final manufacture of the textile goods that reinforce the properties of the fabric.