Iron, Cobalt, Nickel, Vanadium, Molybdenum, Or Palladium Patents (Class 424/646)
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Publication number: 20130115262Abstract: A substrate with an electron donating surface, characterized in having metal particles on said surface, said metal particles having palladium and at least one metal selected from gold, ruthenium, rhodium, osmium, iridium, or platinum, wherein the amount of said metal particles is from about 0.001 to about 8 ?g/cm2.Type: ApplicationFiled: November 12, 2012Publication date: May 9, 2013Applicant: BACTIGUARD ABInventor: Bactiguard AB
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Patent number: 8435496Abstract: A method for providing nanoparticle clusters of controlled dimensions is described. The method involves an activation of individual nanoparticles and the subsequent interaction between activated particles to form a cluster.Type: GrantFiled: December 12, 2007Date of Patent: May 7, 2013Assignee: Dublin City UniversityInventors: Dermot Brougham, Swapankumar Ghosh
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Publication number: 20130108603Abstract: A topical skin care lotion includes materials for supplementing the production of collagen I and III includes a base of lipophillic or lipophobic material and at least one amino acid. The amino acids are alanine and glycine. Other components of the lotion include iron, vitamin C, manganese, silica and cherry fruit extract. Together, these components assist the body with the production of collagen and promote healing of damaged skin. Antioxidants are also provided to protect the skin from oxidative stress by ultraviolet sunlight and environmental hazards.Type: ApplicationFiled: November 2, 2011Publication date: May 2, 2013Inventor: Mark K. Bennett
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Publication number: 20130108709Abstract: Pharmaceutical compositions and methods for the treatment of subjects, including humans, who have or are at risk for various disease, disorders and conditions, including, mitochondria-associated diseases, disorders, and conditions, including respiratory chain disorders, and diseases, disorders and conditions associated with or characterized at least in part by mitochondria swelling, mitochondria dysfunction, mitochondria leaking, oxidative stress, increased mitochondria number, increased mitochondria and mitochondria-related protein mass, and increased mitochondria and related-related proteins expression.Type: ApplicationFiled: October 25, 2012Publication date: May 2, 2013Inventors: Garth James Smith Cooper, Anthony Ronald, John Phillips, Nancy Xiuyin Chen, Deming Gong, Maria Jullig, Anthony John, Rodney Hickey, Sarah Glyn-Jones
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Publication number: 20130103120Abstract: There is disclosed therapeutic devices or sanitary articles intended for the treatment of diseases and/or disorders of the tonic/postural system, containing a composition which emits and/or reflects light energy in the far infrared spectrum and which includes a ceramic material. Also disclosed is the use of a composition which emits and/or reflects light energy in the far infrared spectrum and which includes a ceramic material in the preparation of therapeutic devices or sanitary articles intended for the treatment of diseases and/or disorders of the tonic/postural system, in particular, orthodontic devices, glasses and plasters.Type: ApplicationFiled: June 29, 2011Publication date: April 25, 2013Inventor: Sergio Ettore Salteri
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Publication number: 20130091611Abstract: The present invention provides the use of nanoparticles of a compound of general formula MnXy, where M is (i) a metal selected from the group consisting of Calcium (Ca), Aluminium (Al), Zinc (Zn), Nickel (Ni), Tungsten (W) or Copper (Cu); or (ii) a non-metal selected from the group consisting of Silicon (Si), Boron (B) or Carbon (C); in which n is equal to 1, 2, or 3, and X is (iii) a non-metal selected from the group consisting of Oxygen (O), Nitrogen (N), or Carbon (C); or (iv) an anion selected from the group consisting of phosphate (PO43?), hydrogen phosphate (HPO42?), dihydrogen phosphate (H2PO4?), carbonate (CO3), silicate (SiO42?), sulphate (SO42?), nitrate (NO3?), nitrite (NO2?); in which y is equal to 0, 1, 2, 3 or 4; for use in reducing and/or preventing virus transmission. Articles of protective clothing or filters are provided in which the fibres are coated with said nanoparticles for use in reducing and/or preventing virus transmission.Type: ApplicationFiled: November 30, 2012Publication date: April 18, 2013Inventors: Guogang Ren, John S. Oxford, Prof., Paul William Reip, Robert Lambkin-Williams, Alexander Mann
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Publication number: 20130089578Abstract: An insecticide including diatomaceous earth in a liquid mixture of water and one or more additives is provided. The diatomaceous earth may be present in an amount between at least 20 and less than 25 weight percent of the insecticide. The insecticide is applied in liquid form to surfaces for controlling the spread of insects. The liquid component of the insecticide evaporates leaving a thin layer of the dried diatomaceous earth. Insects traversing the diatomaceous earth layer are scratched and scraped by the layer, which results in water loss from the exoskeleton and eventually death.Type: ApplicationFiled: October 10, 2012Publication date: April 11, 2013Applicant: WINFIELD SOLUTIONS, LLCInventor: WINFIELD SOLUTIONS, LLC
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Publication number: 20130089623Abstract: The present invention provides methods and compositions for treating thyroid-related medical conditions. Many thyroid-related medical conditions exist that go undiagnosed and untreated. These conditions may be prevented and treated with reduced folates and vitamin B12. Administration of reduced folates and vitamin B12 will prevent or treat cerebrospinal folate deficiency, which is linked to thyroid-related medical conditions. Administration of reduced folates and vitamin B12 will also prevent or treat conditions associated with masked megaloblastic anemia and hypothyroidism, and other conditions brought upon through improper thyroid function. Additionally, it is commonplace to treat many thyroid conditions with anti-thyroid drugs or thyroid stimulating drugs. This practice alone is also responsible for causing, or not beneficially addressing, adverse conditions that can be prevented or treated through the methods and compositions discussed herein.Type: ApplicationFiled: November 28, 2012Publication date: April 11, 2013Inventor: Linzy O. Scott, III
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Publication number: 20130084272Abstract: The present invention relates to compositions, kits and methods for the administration of compositions and kits for supplementation with twelve carbon chain fatty acids or twelve carbon chain acylglycerols; and specifically for the supplementation with twelve carbon chain fatty acids such as lauric acid and twelve carbon chain acylglycerols such as monolaurin; and specifically for the co-supplementation with other vitamins, minerals and nutrients.Type: ApplicationFiled: September 29, 2011Publication date: April 4, 2013Inventors: Philippe PERRIN, Guillaume HERRY, Cecile BOYER-JOUBERT
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Patent number: 8409598Abstract: It is an object of the present invention to provide a copper ion-producing composition that has a copper ion (mineral)-based germicidal activity against Legionella spp., Escherichia coli, Staphylococcus aureus, and saprophytic bacteria occurring in the water in drinking water storage tanks, hot springs, bathhouses, and pools, and that can supply mineral, and also to provide a granular composition that contains this copper ion-producing composition. The copper ion-producing composition is obtained by mixing 0.3 to 10 weight parts surfactant with 100 weight parts metallic copper powder. The granular composition is obtained by kneading this copper ion-producing composition with poorly water-soluble material that has a softening point of not less than 70° C. The granular composition is also obtained by coating the copper ion-producing composition on the surface of poorly water-soluble material that has a softening point of not less than 70° C.Type: GrantFiled: March 10, 2006Date of Patent: April 2, 2013Inventor: Iwao Hishida
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Publication number: 20130078288Abstract: A method and composition for administering a therapeutic composition to a lesion comprising about 20% to about 50% ethanol and other novel therapeutic agents.Type: ApplicationFiled: November 20, 2012Publication date: March 28, 2013Inventor: Chun Ho Yu
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Patent number: 8398957Abstract: An aerosol composition comprising: 0.01 wt % to 1.00 wt % sodium borate; 0.01 wt % to 1.50 wt % polyglycerol ester surfactant; <30 wt % propellant; and 67.5 wt % to 85.0 wt % water. Methods of manufacture of an aerosol air freshener are also described wherein the aerosol composition further comprises a fragrance.Type: GrantFiled: October 8, 2008Date of Patent: March 19, 2013Assignee: Reckitt Benckiser (UK) LimitedInventors: Chris Bates, Erin Corstanje, Chris Jones, Maud Portier, Hannah Tipple
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Patent number: 8399506Abstract: The present invention relates to the use of combinations of 4-bromo-2-(4-chloro-phenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile and an oxidizing agent, for eradicating, eliminating or reducing aquatic organisms in ballast water or bilge water whereby 4-bromo-2-(4-chloro-phenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile and the oxidizing agent are in respective proportions to provide a synergistic effect against fouling organisms. Suitable oxidizing agents are e.g.Type: GrantFiled: August 6, 2007Date of Patent: March 19, 2013Assignee: Janssen Pharmaceutica, NVInventor: Tony Mathilde Jozef Kempen
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Publication number: 20130064900Abstract: New methods, compositions, and processes for the treatment of symptoms of dandruff using cellular adhesion modulators are disclosed.Type: ApplicationFiled: September 14, 2011Publication date: March 14, 2013Inventors: Bert W. Herring, Judi C. Herring
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Publication number: 20130052274Abstract: Nutritional compositions and methods of making and using the nutritional compositions are provided. In a general embodiment, the present disclosure provides a nutritional composition including exogenous vitamin K2. The nutritional compositions may further include an additional component selected from the group consisting of phosphorus, magnesium, zinc, iron, copper, manganese, calcium, vitamin D, osteopontin and combinations thereof.Type: ApplicationFiled: September 1, 2010Publication date: February 28, 2013Applicant: Nestec S.A.Inventors: Douglas Richard Bolster, Zamzam Kabiry Roughead
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Publication number: 20130052278Abstract: The present disclosure provides a rapidly disintegrating orally administrable powder. The powder may include an active ingredient such as a dietary supplement. Methods of using the same are also provided herein.Type: ApplicationFiled: March 10, 2011Publication date: February 28, 2013Applicant: RICH VITAMINS LLCInventors: Hallie N. Rich, Michelle G. Cannon
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Publication number: 20130052275Abstract: This invention is a topical treatment for the skin, used for skin enhancement, firming, smoothing, refining and to reduce the appearance of cellulite; that has a self-warming or thermogenic effect comprised of a base combination of warming herbs (Ayurvedic), being any herbs that create a warming effect, combined with dietary minerals that can be blended together in any ratio.Type: ApplicationFiled: August 22, 2012Publication date: February 28, 2013Inventor: Michelle Ward
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Publication number: 20130052279Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and metal ions. Reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of metal ions to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.Type: ApplicationFiled: March 24, 2011Publication date: February 28, 2013Applicant: MEDESIS PHARMAInventor: Jean-Claude Maurel
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Patent number: 8383085Abstract: A method of making iron-containing nanoparticles (e.g., magnetite nanoparticles) that includes contacting an iron-containing precursor with a reducing agent at a temperature less than 200° C. and allowing the mixture to react to form magnetite nanoparticles.Type: GrantFiled: February 22, 2010Date of Patent: February 26, 2013Assignee: University of ManitobaInventors: Torsten Hegmann, Vinith Yathindranath, David F. Moore, Johan van Lierop
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Publication number: 20130045183Abstract: The present disclosure relates to non-acidic extracts or fractions selected from a Boswellia low polar gum resin extract fraction (BLPRE), a Boswellia volatile oil fraction (BVOIL), and a Boswellia oil fraction (BOIL) and their compositions. BLPRE, BOIL, and BVOIL are each derived from the gum resin of a Boswellia species. These compositions are useful for improving mental condition, enhancing brain functions such as cognition, memory, learning, communication and brain health, for treating impaired memory, and for preventing, control or treating memory and cognition related disorders/diseases. Additionally, BOIL, BVOIL, and mixtures of BOIL and BVOIL are useful for enhancing the bioavailability of a biological agent.Type: ApplicationFiled: September 14, 2012Publication date: February 21, 2013Applicant: LAILA NUTRACEUTICALSInventors: Ganga Raju GOKARAJU, Rama Raju GOKARAJU, Venkata Kanaka Ranga Raju GOKARAJU, Trimurtulu GOLAKOTI, Kiran BHUPATHIRAJU, Venkata Krishna Raju ALLURI
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Patent number: 8377482Abstract: The invention discloses a trace element solution, which comprises at least one metal selected from the group comprising selenium, copper, zinc, manganese and chromium; and at least one component selected from the group comprising a vitamin, a vaccine, a growth stimulant, a dewormer, iron dextran, an antibiotic and a synchronization preparation. The synchronization preparation is a combination of injectable hormonal preparations, inplantable hormonal preparations, intravaginal hormonal preparation and other slow release hormonal preparation. The antibiotics include oral, injectable and implantable theurapeutic remedies. The vaccine includes antigens and a combination of antigens and adjuvents. The growth stimulants include zeranol, estradiol, testosterone, progesterone and trenbolone acetate. The dewormer includes macrocydic lactones, leramizoles, benzimidazoles and salicylanilides. The macrocydic lactones include doramectin, ivermectin, abamectin and moxidectin.Type: GrantFiled: September 7, 2005Date of Patent: February 19, 2013Assignee: Warburton Technology LimitedInventors: Robert N. Laurie, William A. Smith
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Publication number: 20130039961Abstract: A personal care composition is disclosed comprising abrasive particles. The personal care composition may take a variety of forms such as a leave-on composition or an emulsion and/or may comprise one or more actives or agents.Type: ApplicationFiled: June 20, 2012Publication date: February 14, 2013Inventors: Denis Alfred GONZALES, Martin Ian James, Geert Andre Deleersnyder, Steven Ray Merrigan, Thomas Allen Desmarais, Paul Robert Tanner, Binwu Tao
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Publication number: 20130039953Abstract: A method for treating a surface with a therapeutic agent is disclosed. The method comprises precipitating a therapeutic agent from a hydrophilic polymeric base layer with which the therapeutic agent has been complexed, to form a layer comprising microparticles of the therapeutic agent on the hydrophilic polymeric base layer, the hydrophilic polymeric base layer being grafted to the surface. Devices comprising a surface having a hydrophilic polymeric base layer comprising a hydrophilic polymer grafted to the surface and a layer comprising microparticles of a therapeutic agent disposed on and complexed with the hydrophilic polymeric base layer are also disclosed.Type: ApplicationFiled: July 6, 2012Publication date: February 14, 2013Applicant: Covalon TechnologiesInventors: Vyacheslav Dudnyk, Valerio DiTizio
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Patent number: 8372442Abstract: A ready-to-consume liquid nutritional composition which is particularly suitable for use by morbidly obese patients pre- and post-bariatric surgery. The composition comprises an energy content between 80-160 kcal/100 ml, a protein content between 40-80 En %, a digestible carbohydrate content between 0-30 En %, a fat content between 5-40 En %, a soluble dietary fiber content between 1.5-8 g/100 kcal, and micronutrients. The micronutrients comprise calcium in an amount between 150-1000 mg/100 kcal, phosphorus in an amount between 100-1000 mg/100 kcal, with a Ca:P ratio of at least 1.0, iron in an amount between 4-50 mg/100 kcal, vitamin D in an amount between 2-400 mcg/100 kcal and vitamin B12 in an amount between 0.5-300 mcg/100 kcal.Type: GrantFiled: December 13, 2010Date of Patent: February 12, 2013Assignee: N.V. NutriciaInventors: Edward Lucian Sliwinski, Marcel Minor
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Patent number: 8372441Abstract: The subject invention concerns methods for preparing alkaline earth ferrates and the preparation of hemostatic compositions from alkaline earth ferrates. In one embodiment, the alkaline earth ferrate is strontium ferrate. In one embodiment, methods of the invention comprise heat treating mixtures of alkaline earth oxides and/or peroxides with iron oxides, such as hematite or magnetite. The subject invention also concerns hemostatic compositions produced using metallic oxides that are reacted with alkaline earth oxides and/or peroxides and the methods used to produce the hemostatic compositions.Type: GrantFiled: November 30, 2009Date of Patent: February 12, 2013Assignee: Biolife, LLCInventors: John Alfred Thompson, John Hen
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Publication number: 20130034594Abstract: A fiber containing ferrate, which comprises (1) one or more ferrate compounds, wherein the ferrate compound is selected from a group consisting of a metal ferrate(V) compound, metal ferrate(VI) compound, and a mixture thereof; and (2) one or more nonaqueous polymers. Also, methods are disclosed that make and/or use the fibers.Type: ApplicationFiled: April 21, 2011Publication date: February 7, 2013Applicant: BATTELLE MEMORIAL INSTITUTEInventors: Bruce F. Monzyk, Robert D. Giammar, Ada Cowan
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Patent number: 8361504Abstract: The subject invention pertains to materials and methods for stopping or decreasing the blood flow from an open wound or medical or surgical procedure. Compositions of the invention comprise a salt form of a cross-linked polyacrylic acid. In one embodiment, the composition comprises a sodium salt of a polyacrylic acid. Compositions of the invention can also optionally comprise one or more different salt ferrates, and/or a cationic exchanger resins, and/or a silver compound. In an exemplified embodiment, a composition of the invention comprises sodium polyacrylate provided in a dry powdered form. Polyacrylate compositions of the invention can be applied directly to a wound or treatment site, or they can be incorporated into a wound dressing, such as a bandage. The clot or scab formed at a wound or treatment site treated with the present invention is extremely elastic and exhibits considerable tensile strength when stretched to the breaking point.Type: GrantFiled: April 9, 2009Date of Patent: January 29, 2013Assignee: Biolife, LLCInventors: John Hen, John Alfred Thompson, Talmadge Kelly Keene, Michael H. Tollon, Mark Travi, Roger Thomas
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Patent number: 8357696Abstract: Disclosed herein are formulations of fluoroquinolones suitable for aerosolization and use of such formulations for aerosol administration of fluoroquinolone antimicrobials for the treatment of pulmonary bacterial infections. In particular, inhaled levofloxacin specifically formulated and delivered for bacterial infections of the lungs is described. Methods include inhalation protocols and manufacturing procedures for production and use of the compositions described.Type: GrantFiled: January 28, 2010Date of Patent: January 22, 2013Assignee: Mpex Pharmaceuticals, Inc.Inventors: Mark W. Surber, Keith A. Bostian, Michael N. Dudley, Olga Rodny, David C. Griffith
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Patent number: 8349376Abstract: A novel dietary supplement is featured which can benefit individuals suffering from various conditions such as nutritional deficiencies, vitamin deficiencies, aging, dementia/Alzheimer's disease, high blood pressure, high cholesterol, coronary artery disease, stroke and mental cognition.Type: GrantFiled: March 8, 2011Date of Patent: January 8, 2013Inventor: Mark S. Bezzek
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Publication number: 20130004586Abstract: Compositions, solid polymeric compositions, and/or articles of manufacture are provided that can include a polymer matrix having a plurality of ion-exchange particles distributed therein. Products by process are provided that can include prior to solidifying the polymeric precursors, blending the precursors with ion-exchange particles to form a mixture, and solidifying the mixture to form a solid polymeric composition product. Solid polymeric composition production methods are also provided that can include providing a plurality of ion-exchange particles, prior to solidifying the polymeric precursors, blending the precursors with the ion-exchange particles to form a mixture, and solidifying the mixture to form a solid polymeric composition. Article of manufacture production methods are provided that can include incorporating a solid polymeric composition into an article of manufacture, the solid polymeric composition including a polymer matrix and a plurality of ion-exchange particles distributed therein.Type: ApplicationFiled: June 25, 2012Publication date: January 3, 2013Inventors: David J. Vachon, Nathan Knapp
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Publication number: 20130004544Abstract: The present invention is directed to synthetic bactericidal compositions having clay like properties and a method of using these compositions to topically treat bactenally-caused skin infections and skin diseases. The compositions within the scope of the invention compnse a bactericidal effective amount of a reducing agent, such as py?te, marcasite, pyrrhotite, FeS2, FeS, FeS04—or other reducing agents having like properties, and a natural clay or clay mineral and/or synthetic clay or clay mineral, or other suitable matenals having clay-like properties. The synthetic bactericidal compositions are synthesized by adding the reducing agent to the clay or clay mineral. It is the presence of the reducing agent in said compositions that renders them bacte?cidal.Type: ApplicationFiled: June 1, 2010Publication date: January 3, 2013Inventors: David W. Metge, Lynda Williams, Dennis D. Eberl, Alex E. Blum, Ronald W. Harvey
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Publication number: 20130004588Abstract: Compositions and methods for treating and/or preventing conditions such as diaper rash and atopic dermatitis are disclosed. The compositions and methods are particularly useful in the treatment and prevention of diaper rash and diaper dermatitis caused by the prolonged contact of human skin with body waste. The methods employ the topical application of a trypsin-inhibiting agent to the area in need of such treatment, or the area where prevention is desired. The trypsin-inhibiting agent is preferably a divalent cation.Type: ApplicationFiled: June 28, 2011Publication date: January 3, 2013Inventors: Connie B. Lin, Euen Thomas Graham Ekman Gunn, Ya-Ping Hu, Neema Kulkarni, Mary Catherine Mack
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Patent number: 8337887Abstract: The present invention concerns a rapidly disintegrating taste-masked tablet having both hardness and non-friability properties comprising at least one active principle selected from the group of mineral salts, vitamins and mixtures thereof, the active principle being coated by a sweetening agent wherein the weight ratio of the active principle to the sweetening agent is from 0.2 to 3, and starch and microcrystalline cellulose in a weight ratio of starch to microcrystalline cellulose from about 0.76 to 0.85, and at least one free flow aid. It also concerns a method for the preparation of such a tablet.Type: GrantFiled: March 11, 2004Date of Patent: December 25, 2012Assignees: Laboratories Pharmaceutiques Rodael, Laboratories NutrisetInventor: Paul Equipart
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Publication number: 20120316259Abstract: This invention relates to a process for the co-encapsulation of biocidally active ingredients in a clay mineral, the process comprising the step of bringing the clay mineral into contact with a biocidally active nitrogen compound that contains at least one hydrocarbon group with 6 to 20 carbon atoms, and at the same time or subsequently with at least one biocidally active compound selected from the group consisting of 2-n-octyl-4-isothiazoline-3-one, 3-iodopropenylbutyl-carbamate and tetrahis(hydroxymethyl)phosphonium sulfate. And the use of such encapsulated product in water based paints, coatings and varnishes.Type: ApplicationFiled: February 15, 2011Publication date: December 13, 2012Applicant: CLARIANT S.A. BRAZILInventors: Antonio Pedro de Oliveira Filho, Wagner Claudio Da Silva, Manlio Gallotti, Alexandra Paschoalin Menezes, Karine Framesqui Righi, Marcia Regina Da Silva Rios
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Patent number: 8329227Abstract: The present invention provides formulas for producing compositions for the structural/functional nutritional support for those who struggle with poor focus, concentration and/or memory. In addition, the present invention provides compositions comprising nutritional/botanical factors helpful to those who subjectively experience transient mental fatigue or poor cognitive function. The compositions of this invention consist primarily of the following ingredients B-complex vitamins, antioxidants, minerals, phosphatidyl serine (PS), choline, dimenthyl-aminoethanol (DMAE), docosahexaenoic acid (DHA), L-pyroglutamic acid, as well as herbal extracts from Bacopa monniera, Vinca minor, and Huperzia serrata. The present invention also relates to the administration of these compounds to alleviate mental fatigue or poor cognitive function.Type: GrantFiled: December 7, 2004Date of Patent: December 11, 2012Assignee: Factor Nutrition Labs, LLCInventor: Kyl L. Smith
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Publication number: 20120308668Abstract: The present invention relates to the field of human health, and more particularly to the treatment of attention deficit/hyperactivity disorder (ADHD) with mazindol. The latter can be administered as monotherapy or in combination with one or more compounds, including psychostimulants, for the indication of ADHD and associated or co-morbid symptoms.Type: ApplicationFiled: August 21, 2012Publication date: December 6, 2012Applicant: ASSISTANCE PUBLIQUE-HOPITAUX DE PARISInventor: Eric Konofal
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Publication number: 20120301529Abstract: The present invention refers to the use of a powder of vitreous composition, characterised in that it has a minimum CaO content of 10% by weight, as biocideType: ApplicationFiled: December 7, 2010Publication date: November 29, 2012Applicant: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICASInventors: Jose Moya Corral, Leticia Esteban, Carlos Pecharroman, Francisco Malpartida
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Publication number: 20120302819Abstract: In this disclosure, we describe a method for the treatment of tumor(s) or tumor cell(s) or cancer(s) in a subject in need by the generation of heat. The latter is produced by chains of magnetosomes extracted from whole magnetotactic bacteria and subjected to an alternative magnetic field. These chains of magnetosomes yield efficient antitumoral activity whereas magnetosomes unbound from the chains or kept within the whole bacteria produce poor or no antitumoral activity. The introduction of various chemicals such as chelating agents and/or transition metals within the growth medium of the bacteria improves the heating properties of the chains of magnetosomes. Moreover, the insertion of the chains of magnetosomes within a lipid vesicle is also suggested in order to favor their rotation in vivo and hence to improve their heating capacity. The vesicle can contain an antitumoral agent together with the chains of magnetosomes. In this case, the agent is released within the tumors by heating the vesicle.Type: ApplicationFiled: November 18, 2010Publication date: November 29, 2012Inventors: Edouard Alphandery, Stéphanie Faure, Imène Chebbi
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Publication number: 20120288553Abstract: The present invention provides a method for controlling toxicity of metallic particles and a low-toxicity composite of metallic nanoparticles and inorganic clay. The metallic nanoparticles are effective in preventing infection and in skinning over, and thus suitable for treating scalds/burns. In the composite, the weight ratio of metallic nanoparticles to inorganic clay preferably ranges 0.1/99.9 to 6.0/94.0 in a size of about 5 to 100 nm. Preferably, the metal is silver and the inorganic clay is nano silicate platelets.Type: ApplicationFiled: July 14, 2012Publication date: November 15, 2012Applicant: NATIONAL TAIWAN UNIVERSITYInventors: Jiang-Jen Lin, Hong-Lin Su, Fu-Chuo Peng, Chia-Yu Chu, Ying-Fang Chiu, Pei-Ru Li, Hsi-Tai Sun
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Publication number: 20120282311Abstract: The present invention relates to pigments with improved and adjustable sparkling effect comprising A) a plate-like substrate of perlite coated with (a) dielectric material, and/or metal; and B) a plate-like substrate of mica, coated with (a) dielectric material, and/or a metal; and a process for their production and their use in paints, ink jet printing, for dyeing textiles, for pigmenting coatings (paints), printing inks, plastics, cosmetics, glazes for ceramics and glass. The pigments show an improved sparkle effect; in particular an attractive high sparkle intensity.Type: ApplicationFiled: October 18, 2010Publication date: November 8, 2012Applicant: BASF SEInventors: Raimund Schmid, Norbert Mronga, Patrice Bujard, Steven Jones, Paul Cao
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Publication number: 20120282350Abstract: The present invention relates to composition containing sialic acids or precursors, and their use to improve performance-related and social parameters in mammals, particularly humans and horses. The daily dosage is preferably selected from the group consisting of 1 microgram to 100 mg/day, 100 microgram to 20 mg/day, and 200 microgram to 10 mg/day.Type: ApplicationFiled: May 4, 2012Publication date: November 8, 2012Applicant: LIFE SCIENCE NUTRITION ASInventor: Jan Remmereit
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Publication number: 20120282182Abstract: Nanoparticle clusters are described. In particular nanoparticle clusters formed from two or more individual nanoparticles of different types are described and methods for fabricating such nanoparticle clusters are further described. These nanoparticle clusters are fabricated by surface activating individual ones of the plurality of nanoparticles by desorption of surfactant molecules from the surface of the coated nanoparticles through exposure of the individual ones of the plurality of nanoparticles to an activating agent.Type: ApplicationFiled: December 17, 2010Publication date: November 8, 2012Applicant: DUBLIN CITY UNIVERSITYInventors: Dermot Brougham, Carla Meledandri, Jecek Stolarczyk, Tsedev Ninjbadgar
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Publication number: 20120283096Abstract: The present invention relates to (i) a plant growth-improving agent containing a growth-improving component that increases a concentration of an oxoanion in an area around a plant, the oxoanion being heavier than a sulfate ion and containing four oxygen atoms, (ii) a seed to which such a plant growth-improving agent has been applied, and (iii) a plant growth-improving method including a cultivating step of growing a plant in the presence of such a growth-improving component.Type: ApplicationFiled: January 26, 2011Publication date: November 8, 2012Applicant: Incorporated Administrative Agency National Agricu lture and Food Research OrganizationInventor: Yoshitaka Hara
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Patent number: 8303941Abstract: A composition comprising mineral water and a chelating agent present in an amount sufficient to maintain all of the minerals in the water in solution. The mineral water is preferably obtained from Mount Clemens, Mich., US, and is preferably chelated with an ammonium and/or a sodium salt of an acid selected from the group consisting of ethylenediaminetetraacetic acid, nitrilotetraacetic acid, ?-alaninediacetic acid, ethylenediaminosuccinic acid, aminotrimethylenephosphoric acid, serinediaacetic acid, asparaginediacetic acid, methylgylcinediacetic acid and mixtures thereof. The resultant chelated mineral water may be combined with a cosmetically acceptable skin-conditioning agent and a cosmetically acceptable topical carrier, thereby resulting in a cosmetic composition that will confer beneficial effects on the skin, e.g., softening, hydrating and healing effects.Type: GrantFiled: April 19, 2008Date of Patent: November 6, 2012Assignee: Geologix, Inc.Inventor: Stephen Musumeci
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Publication number: 20120277517Abstract: An embodiment in accordance with the present invention provides a thermo-chemoembolization formulation and method for enhanced interventional image-guided therapy for cancer. The T-C formulation includes magnetic iron oxide nano-particles (MIONs) that heat when exposed to an alternating magnetic field (AMF), a liquid tumorphilic drug carrier that enhances tumor retention of the T-C formulation, and a chemotherapeutic or radiotherapeutic agent. The T-C formulation enhances delivery of heat and chemo- or radio-therapeutic agents with hyperthermia produced by magnetic nanoparticles to improve therapeutic outcomes. The magnetic nanoparticles and tumorphilic drug carrier also allow for multimodal image-guided monitoring of treatment and patient follow-up. The method for enhanced interventional image-guided therapy for cancer includes using an AMF to heat the T-C formulation and activate the thermotherapy.Type: ApplicationFiled: April 9, 2012Publication date: November 1, 2012Applicant: The Johns Hopkins UniversityInventors: Robert Ivkov, Eleni Liapi
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Publication number: 20120276165Abstract: The present invention provides a composition comprising an acidified aqueous solution of (1) micro colloidal silicic acid, (2) boric acid, and (3) a water absorbing additive, having a pH value of equal to or less than 1, wherein the micro colloidal silicic acid has particle sizes in the range of 1-8 nm, especially in the range of 1.5-6 nm. The invention also provides a particulate product obtainable by the method according to claim 18, wherein the particles comprise (1) silicic acid, (2) boric acid, and (3) the water absorbing additive, and wherein at least 90% of the particles in the particulate product have particle sizes in the range of 0.3-5 ?m.Type: ApplicationFiled: December 8, 2010Publication date: November 1, 2012Inventors: Henk Maarten Laane, Walter Ferdinand Witterland
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Publication number: 20120276218Abstract: A biocompatible composition for tissue repair or regeneration in mammals comprising one or more glass former compounds selected from the group consisting of B2O3, P2O5, and SiO2 and director elements selected from the group consisting of Cu, Sr, Zn, Fe, Mn, Cr, V, Nb, Mo, W, Ba, Co, S, Al, Ti, Y, Mg, Si and/or Ni to promote in vivo calcium compound formation of calcium carbonate or other calcium compounds other than hydroxyapatite. Upon direct application of the biocompatible composition to a mammalian host, calcium carbonate or other calcium compounds other than hydroxyapatite form upon bioreaction of the composition with bodily fluids.Type: ApplicationFiled: July 6, 2012Publication date: November 1, 2012Applicant: THE CURATORS OF THE UNIVERSITY OF MISSOURIInventors: Steven B. Jung, Delbert E. Day
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Publication number: 20120269900Abstract: The present invention relates to compositions and methods for deterring and repelling all types of organisms capable of sensing electric or magnetic fields, including insects and arachnids. The compositions contain electrically or magnetically imprintable substances comprising an electric or magnetic charge or imprint, wherein the imprint contains the signature of at least one target organism; and an acceptable carrier.Type: ApplicationFiled: October 14, 2011Publication date: October 25, 2012Inventor: D. Tobin Watkinson
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Patent number: 8293257Abstract: An oily dispersion of an inorganic microparticle oxide powder that exhibits excellent texture has superior compatibility with other cosmetic material components. The oily dispersion contains only two components of a dispersion medium and a surface-treated inorganic microparticle oxide powder, wherein the dispersion medium is an oil, the surface-treated inorganic microparticle oxide powder is a powder surface-treated with branched fatty acid containing isostearic acid as a primary constituent component or a metal salt containing isostearic acid as a primary constituent component at an amount of 1 to 30% by weight with respect to the powder as a base material, and the surface-treated inorganic microparticle oxide powder has a solid concentration of 25% by weight or more and a viscosity of 2,000 mPa·s or less at 25° C. in the preparation of the oily dispersion.Type: GrantFiled: December 28, 2011Date of Patent: October 23, 2012Assignee: Tayca CorporationInventors: Kazunori Yagi, Naoki Kanda
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Patent number: 8293779Abstract: The present invention relates to the field of human health, and more particularly to the treatment of attention deficit/hyperactivity disorder (ADHD) with mazindol. The latter can be administered as monotherapy or in combination with one or more compounds, including psychostimulants, for the indication of ADHD and associated or co-morbid symptoms.Type: GrantFiled: April 11, 2007Date of Patent: October 23, 2012Assignee: Assistance Publique-Hopitaux de ParisInventor: Eric Konofal