Potassium Chloride Patents (Class 424/679)
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Patent number: 11647774Abstract: There are proposed substance mixtures comprising (a) 20 to 80% by weight of monocyclic terpenes and (b) 80 to 20% by weight of active substances selected from the group consisting of rebaudiosides or plant extracts comprising them, steviosides or plant extracts comprising them, naringin dihydrochalcone, mogrosides or plant extracts comprising them, rubusosides or plant extracts comprising them.Type: GrantFiled: April 25, 2013Date of Patent: May 16, 2023Assignee: SYMRISE AGInventors: Gerhard Krammer, Sven Siegel, Günter Kindel
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Patent number: 11541005Abstract: Aspects herein relate to systems and methods for delivery of biologic agents to the central nervous system. In various embodiments, a method of administering a therapeutic agent to the central nervous system (CNS) is included. The method can include injecting a therapeutic agent into a first cerebrospinal fluid (CSF) region of the subject. The method can further include establishing fluid communication between a fluid reservoir and a second cerebrospinal fluid (CSF) region of a subject, the fluid having a hydraulic pressure at or above an intracranial pressure. The method can further include infusing a hyperosmotic fluid systemically. Other embodiments, including kits and systems are also included herein.Type: GrantFiled: February 8, 2018Date of Patent: January 3, 2023Assignee: New Hope Research Foundation, Inc.Inventor: John G. Keimel
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Patent number: 11510884Abstract: The present invention relates to a bowel cleansing composition comprising polyethylene glycol and ascorbate ingredients, the bowel cleansing composition of the present invention being easier to take, while having an excellent bowel cleansing effect, thereby being usable as an effective bowel cleansing agent.Type: GrantFiled: February 1, 2019Date of Patent: November 29, 2022Inventors: Joon Youb Lee, Woo Young Jang, Yiseul Song
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Patent number: 11278590Abstract: A method of treating bacterial or fungal nail infections may include mixing an antibiotic or antifungal injectable medication and a diluent to formulate a topical nail composition. The topical nail composition may be administered directly to a nail affected by the bacterial or fungal infection.Type: GrantFiled: May 10, 2018Date of Patent: March 22, 2022Assignee: CMPD LICENSING, LLCInventor: Jay Richard Ray, II
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Patent number: 10993996Abstract: The present invention is directed to a digestive enzyme composition comprising an enterically coated digestive enzyme product, administrable nutritional medium, and a pharmaceutically acceptable low viscosity oily ingredient. The process for the preparation of the digestive enzyme composition comprises adding an enterically coated digestive enzyme product to a administrable nutritional medium and pharmaceutically acceptable low viscosity oily ingredient. The invention further provides a method for treating a patient suffering from exocrine pancreatic insufficiency related condition comprising administering to the patient a therapeutically effective dose of the digestive enzyme composition by means of a feeding tube.Type: GrantFiled: August 4, 2014Date of Patent: May 4, 2021Assignee: Allergan Pharmaceuticals International LimitedInventors: Devrim Eren, Ruth Thieroff-Ekerdt, Luigi Boltri, Vincenza Pironti, Letizia Ubliglia
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Patent number: 10869492Abstract: A beverage product comprising a beverage in a sealed container is provided. The beverage comprises, in water, a combination of buffering components selected from (a) citric acid and trisodium citrate, (b) tartaric acid and disodium tartrate, or (c) malic acid and disodium malate, and glucose and sodium chloride, wherein the beverage has a pH of lower than 4.0. A method and an apparatus suited for producing such a beverage product are also provided.Type: GrantFiled: March 3, 2017Date of Patent: December 22, 2020Inventor: Nobuto Washio
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Patent number: 10526318Abstract: Oral formulations of benzofuran compounds which modulate cannabinoid receptors are presented. Methods of using these formulations for treatment of cannabinoid receptor-mediated disease, including neuropathic pain and addition, are also described.Type: GrantFiled: January 5, 2018Date of Patent: January 7, 2020Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Joseph Foss, Mohamed Naguib Attala
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Patent number: 10040729Abstract: Provided is a growth supplement for efficient production of agricultural and livestock products, more specifically, a growth supplement for environment-friendly crop cultivation and livestock rearing to increase yields of crops and livestock, which is prepared by mixing specific amounts of antibiotic fruit juices, one or more sources of sugar, one or more sources of hydrogen carbonate, one or more sources of chloride ion and antifebrile vegetable juices depending on crops (species) and cultivation (livestock) conditions to feed the livestock or crops. The growth supplement is prepared by admixing and stirring antibiotic fruit juices in an amount of 2 to 10 parts by weight; the source of hydrogen carbonates in an amount of 1 to 4 parts by weight; the source of chloride ion in an amount of 1 to 4 parts by weight; and antifebrile vegetable juices in an amount of 2 to 8 parts by weight, based on 100 parts by the source of sugar.Type: GrantFiled: August 30, 2013Date of Patent: August 7, 2018Assignee: WIZBIO CO., Ltd.Inventors: Yong Guk Kim, Jae Sung Park, Tae Hyoun Kim
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Patent number: 9763979Abstract: The present invention relates to a cardioplegic preparation. According to a preferred embodiment of the invention, the preparation is made of two solutions, the first containing magnesium sulfate, potassium and xylitol, and the other containing procaine.Type: GrantFiled: August 10, 2009Date of Patent: September 19, 2017Assignee: Universitat BernInventors: Erich Gygax, Thierry Carrel, Hendrik Tevaearai
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Patent number: 9427419Abstract: The invention relates generally to compositions comprising dimethylsulfoxide (DMSO) and associated compounds in combination with one or more of the following: fructose 1,6-diphosphate, L-arginine, L-lysine, L-aspartate, and urea. Methods for treating traumatic brain injury, ischemic stroke, atherosclerosis, spinal cord trauma, and neurodegenerative illnesses are also provided.Type: GrantFiled: September 11, 2006Date of Patent: August 30, 2016Assignee: Abela Pharmaceuticals, Inc.Inventor: Jack De La Torre
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Publication number: 20150118326Abstract: The present disclosure provides methods and compositions for treating fungal diseases of plants. In one embodiment, an anti-fungal aqueous composition can comprise: a nitrogen source material having a total nitrogen content in an amount of about 0.1 wt % to about 0.5 wt % of the total weight of the composition, a phosphate source material having total phosphate content in an amount of about 0.05 wt % to about 0.15 wt % of the total weight of the composition, a potassium source material with a soluble potash content in an amount of about 0.05 wt % to about 0.15 wt % of the total weight of the composition, and a sulfur source material in an amount of about 0.005 wt % to about 0.02 wt % of the total weight of the composition.Type: ApplicationFiled: October 6, 2014Publication date: April 30, 2015Inventor: Steven R. Teerlink
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Publication number: 20140352710Abstract: A composition that rejuvenates hair by providing numerous functions for healthy, beautiful hair. The conditioner composition works best after shampooing the hair, whereby oil, grime, and debris are removed and the conditioner can maximize contact with the hair. The composition includes moisturizers that help retain moisture in the hair. The composition also serves as a reconstructor, penetrating the outer cuticle layer of the hair to the cortex and medulla layers of the hair, strengthening its structure through polymer crosslinking. The composition works as an acidity regulator. The composition includes heat absorbing polymers for shielding the hair against excessive heat caused by blow-dryers, curling irons, and hot rollers. The composition includes a surfactant to provide an additional layer to the hair for glossiness. The composition includes vitamins and nutrients efficacious for nourishing the hair follicle and hair strand itself.Type: ApplicationFiled: June 3, 2013Publication date: December 4, 2014Inventor: LILIA MARIA ARDILA
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Publication number: 20140341963Abstract: A composition comprising at least one substance coated with an agent wherein the agent forms a liquid impermeable but gas permeable layer surrounding the said substance and preventing the passage of the said substance through said coating, wherein in-use the said substance is not released into solution in the body, and wherein said substance is selected from one or more of the group consisting of calcium phosphate, sodium chloride, potassium chloride, magnesium chloride, calcium carbonate, and sodium bicarbonate for use in the treatment of osteoporosis and other bone conditions.Type: ApplicationFiled: May 9, 2014Publication date: November 20, 2014Applicant: ActiveSignal Holding LimitedInventor: Ward Warren
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Patent number: 8883762Abstract: The present invention provides a solution for peritoneal dialysis, consisting of at least two single solutions which are combined after a heat sterilization and are administered to a patient, the first single solution containing an osmotic and the second single solution containing a buffer, and one of these single solutions or another single solution containing electrolyte salts. Glucose-like degradation and hydrolysis is avoided during sterilization and storage, while maintenance of a neutral mixture pH is achieved by the osmotic comprising a glucose polymer and/or glucose polymer derivative, and the pH of the first single solution being between 3.5 and 5.0. The present invention further discloses a twin-chambered pouch consisting of a plastic pouch with at least one first chamber and a second chamber, the first single solution being included in the first chamber and the second single solution being included in the second chamber.Type: GrantFiled: March 3, 2008Date of Patent: November 11, 2014Assignee: Fresenius Medical Care Deutschland GmbHInventor: Thomas Zimmeck
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Publication number: 20140314861Abstract: Sustained-released beads providing active ingredients over an extended period of time to an individual orally ingesting the sustained release beads. The sustained-release beads can be part of a suspension wherein the sustained-release beads are suspended and evenly dispersed in the suspension. Binding agents are used to form the structural framework of the sustained released beads and retain the active ingredients without chemical or electrical bonding. The components of the dispersion medium are GRAS designated, making the suspension suitable for use as a food product.Type: ApplicationFiled: June 30, 2014Publication date: October 23, 2014Inventor: Robert Niichel
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Publication number: 20140314863Abstract: Sustained-released beads providing active ingredients over an extended period of time to an individual orally ingesting the sustained release beads. The sustained-release beads can be part of a suspension wherein the sustained-release beads are suspended and evenly dispersed in the suspension. Binding agents are used to form the structural framework of the sustained released beads and retain the active ingredients without chemical or electrical bonding. The components of the dispersion medium are GRAS designated, making the suspension suitable for use as a food product.Type: ApplicationFiled: June 30, 2014Publication date: October 23, 2014Inventor: Robert Niichel
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Publication number: 20140314862Abstract: Sustained-released beads providing active ingredients over an extended period of time to an individual orally ingesting the sustained release beads. The sustained-release beads can be part of a suspension wherein the sustained-release beads are suspended and evenly dispersed in the suspension. Binding agents are used to form the structural framework of the sustained released beads and retain the active ingredients without chemical or electrical bonding. The components of the dispersion medium are GRAS designated, making the suspension suitable for use as a food product.Type: ApplicationFiled: June 30, 2014Publication date: October 23, 2014Inventor: Robert Niichel
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Publication number: 20140255495Abstract: The present invention provides compositions, systems, kits, and methods for preparation prior to a colonoscopy or other gastrointestinal procedure. In particular, the present invention provides a colon lavage system comprising an aqueous portion and a solid portion.Type: ApplicationFiled: May 22, 2014Publication date: September 11, 2014Inventor: Dale R. Bachwich
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Patent number: 8778306Abstract: The present invention provides compositions, systems, kits, and methods for preparation prior to a colonoscopy or other gastrointestinal procedure. In particular, the present invention provides a colon lavage system comprising an aqueous portion and a solid portion.Type: GrantFiled: April 20, 2010Date of Patent: July 15, 2014Inventor: Dale R. Bachwich
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Publication number: 20140186470Abstract: The invention provides a colon cleansing solution comprising: a) 300 to 800 mmol per litre ascorbate anion provided by a mixture of: (i) ascorbic acid and (ii) one or more salts of ascorbic acid the components (i) and (ii) being present in a molar ratio of from 1:4.5 to 1:7.0; and b) 10 to 200 g per litre polyethylene glycol. The invention also provides methods an kits associated with, or making use of the solutions, and compositions for the preparation of the solutions.Type: ApplicationFiled: March 10, 2014Publication date: July 3, 2014Inventors: Lucy Clayton, Alasdair Cockett, Mark Christodoulou, Ian Davidson, Lynn Farrag, Marc Halphen, Leighton Jones, Vanik Petrossian, Peter Stein, David Tisi, Alex Ungar, Jeffrey Worthington
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Publication number: 20140147518Abstract: The invention provides a solution in water comprising the following components at the following concentrations: (a) N×(70 to 130) g/L polyethylene glycol (PEG) having an average molecular weight of 2500 to 4500; (b) N×(1.6 to 4.0) g/L sodium chloride; (c) N×(0.2 to 0.6) g/L potassium chloride; (d) N×(0.6 to 2.2) g/L sodium bicarbonate; (e) N×an amount of preservative; (f) optionally N×an amount of flavouring; and (g) optionally N×an amount of sweetener where N is in the range of 2 to 8. The solution is a concentrate for dilution. In use it is diluted N-fold with water to provide a solution for administration to a subject for the treatment of constipation or faecal impaction. Also provided are solutions, kits, unit doses and methods that comprise or use the solutions.Type: ApplicationFiled: January 28, 2014Publication date: May 29, 2014Applicant: NORGINE BVInventors: Chris Seldon, Dawn Padfield, Frances Morrissey
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Patent number: 8715746Abstract: Provided herein are pharmaceutically acceptable sodium thiosulfate and pharmaceutical compositions thereof. Also provided herein are methods for determining the total non-purgeable organic carbon in a sodium thiosulfate-containing sample. Further provided herein are methods for producing pharmaceutically acceptable sodium thiosulfate. Still further provided herein are methods of treatment comprising the administration of pharmaceutically acceptable sodium thiosulfate.Type: GrantFiled: June 26, 2013Date of Patent: May 6, 2014Assignee: Hope Medical Enterprises, Inc.Inventors: Craig Sherman, Catherine Marie Smith, Kevin Robert Wirtz, Erich Schulze
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Publication number: 20140087007Abstract: Disclosed is a method for rapidly cleansing the intestines and colon of a patient by orally administering an aqueous hypertonic sulfate solution, and then an aqueous isotonic solution to induce purgation, the purgations induced resulting in intestinal and colonic cleansing in less than four hours from the administration of the sulfate solution.Type: ApplicationFiled: March 15, 2013Publication date: March 27, 2014Applicant: Braintree Laboratories, Inc.Inventors: Mark vB. Cleveland, Edmund V. Dennett, JR., John D. McGowan
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Patent number: 8679549Abstract: The invention relates to compositions for use in purgatives, to purgatives comprising such compositions, and to methods for inducing purgation of the colon. The composition may comprise at least one water-soluble sodium salt; at least one water-soluble minimally degradable sugar in an amount, by weight, of from about 1 to about 3 times the weight of sodium ions in said composition; at least one water-soluble potassium salt in an amount, by weight, of from about 0.05 to about 1 time the weight of said sodium salt in said composition; and at least one water-soluble magnesium salt, wherein the weight of magnesium ions in said composition is from 0.1 to about 10 times the weight of sodium ions in said composition.Type: GrantFiled: June 29, 2012Date of Patent: March 25, 2014Inventors: Thomas Julius Borody, Sanjay Ramrakha, John Saxon, Anthony Wettstein
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Patent number: 8632799Abstract: The present invention generally relates to a wet wipe or sheet that is suitable for contacting the skin and removing mucus from the skin. More specifically, the present invention relates to a wet wipe having an aqueous saline component suitable for dissolving and removing mucus in combination with the fabric matrix of the wet wipe. Typically, the fabric matrix of the wet wipe has a capacity of about 125 grams of solution per square meter, and it is impregnated with the aqueous saline solution to a level at or below approximately 80% of the absorbent capacity of the matrix.Type: GrantFiled: November 19, 2010Date of Patent: January 21, 2014Assignee: Little Busy Bodies, LLCInventors: Mindee K. Doney, Julienne M. Pickens
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Publication number: 20140010894Abstract: Sustained-released beads providing active ingredients over an extended period of time to an individual orally ingesting the sustained release beads. The sustained-release beads can be part of a suspension wherein the sustained-release beads are suspended and evenly dispersed in the suspension. Binding agents are used to form the structural framework of the sustained released beads and retain the active ingredients without chemical or electrical bonding. The components of the dispersion medium are GRAS designated, making the suspension suitable for use as a food product.Type: ApplicationFiled: August 23, 2013Publication date: January 9, 2014Applicant: Nano Pharmaceutical Laboratories, LLCInventor: Robert Niichel
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Publication number: 20140010895Abstract: The invention provides a colon cleansing solution comprising: a) 300 to 2000 mmol per litre ascorbate anion provided by ascorbic acid, one or more salts of ascorbic acid, or a mixture thereof; and b) 10 to 200 g per litre polyethylene glycol. The invention also provides methods and kits associated with, or making use of the solutions. The invention also provides a method of cleansing the colon of a subject comprising: — administering to the subject an effective amount of a first cleansing solution; and then after a time interval-administering to the subject an effective amount of a second cleansing solution, where in the two cleansing solutions are as described in the specification.Type: ApplicationFiled: March 9, 2012Publication date: January 9, 2014Applicant: NORGINE BVInventors: Marc Halphen, Hans-Jurgen Gruss, Ian Cox, Alasdair Cockett, Peter Stein, Alex Ungar
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Publication number: 20130309380Abstract: Methods of preserving fresh produce with a produce preservative which extends the shelf life of fresh produce, particularly cut fresh produce, and preserves the texture, flavor, appearance, crispness, and color of the fresh produce, particularly the exposed surface of the fresh produce, are provided. The method comprises: providing a solution of produce preservative comprising: water; a preservative cation which is selected from the group consisting of a strontium ion, lithium ion, barium ion, aluminum ion, copper ion, ammonium ion, iron ion, manganese ion, potassium ion, or mixtures thereof; and ascorbate ions, or erythorbate ions; wherein the ascorbate ions or erythorbate ions and the preservative cation are present in an ion ratio of preferably from 0.2:1 to 8:1, more preferably 0.75:1 to 8:1, even more preferably from 1:1 to 4:1, yet more preferably 1.5:1 to 3:1; most preferably 1.1:1 to 2.5:1; and, applying said produce preservative to the produce.Type: ApplicationFiled: July 26, 2013Publication date: November 21, 2013Applicant: NatureSeal, Inc.Inventors: Chao Chen, Xiaoling Dong, Kenneth James
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Patent number: 8512770Abstract: The present invention comprises an all-natural composition of matter and methods of delivering nutrients, medicines, pain relievers, antioxidants, antidotes, antibiotics and various active ingredients and supplements directly to the affected area of the body. The all-natural carrier composition consists essentially of the combination of a natural oil, water, salt(s), natural emulsifier, natural sugar(s), plant extracts, natural acid(s), starch and natural flavor(s). The active substances that are mixed with the all-natural carrier composition, include, but are not limited to, drugs, vitamins, minerals, antibiotics anti-fungal agents, antioxidants, diuretics, allergy medicines, anti-inflammatory agents, muscle relaxers, pain reducers, diabetic drugs, neuropathy drugs, chemotherapy agents, arthritis drugs, lotions for eczema, shingles, psoriasis, skin rash; herbal medicines, erectile dysfunction drugs, hormones, cholesterol drugs, essential fatty acids, and the like.Type: GrantFiled: July 15, 2011Date of Patent: August 20, 2013Assignee: Dominion Resources Unlimited, LLCInventors: Daniel G. Murray, Michael W. McDonough
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Publication number: 20130196001Abstract: Presented are salt replacement compositions and methods which are useful for replacing dietary sodium and for preventing and treating diseases associated with sodium overconsumption, including diabetes-Type 2.Type: ApplicationFiled: January 23, 2013Publication date: August 1, 2013Applicant: Health & Science, LLCInventor: Health & Science, LLC
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Patent number: 8496973Abstract: Provided herein are pharmaceutically acceptable sodium thiosulfate and pharmaceutical compositions thereof. Also provided herein are methods for determining the total non-purgable organic carbon in a sodium thiosulfate-containing sample. Further provided herein are methods for producing pharmaceutically acceptable sodium thiosulfate. Still further provided herein are methods of treatment comprising the administration of pharmaceutically acceptable sodium thiosulfate.Type: GrantFiled: July 7, 2010Date of Patent: July 30, 2013Assignee: Hope Medical Enterprises, Inc.Inventors: Craig Sherman, Catherine Marie Smith, Kevin Robert Wirtz, Erich Schulze
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Publication number: 20130164384Abstract: The present invention relates to formulations and kits for the treatment of bowel disease, to their use in medicinal preparations and to therapeutic methods thereof.Type: ApplicationFiled: September 5, 2012Publication date: June 27, 2013Applicant: Salix Pharmaceuticals, Ltd.Inventors: Lorin Johnson, William Forbes, Stephana Patton
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Publication number: 20130101684Abstract: The present invention provides edible compositions comprising a compound of the present invention, food products comprising such edible compositions and methods of preparing such food products. The present invention also provides methods of reducing the amount of NaCl in a food product, methods of reducing the sodium intake in a diet, and methods of reducing bitter taste in a food product.Type: ApplicationFiled: April 15, 2011Publication date: April 25, 2013Applicant: Chromocell CorporationInventors: Jane V. Leland, Louise Slade, David Hayashi, William P. Jones, Peter H. Brown, Joseph Gunnet, Daniel Lavery, Jessica Langer, Kambiz Shekdar
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Publication number: 20120301409Abstract: A homeopathic composition and method for treating a variety of skin irritations, wounds, and diseases is disclosed. The homeopathic composition may contain as active ingredients salicyclic acid, trona or one of its salts, and at least one homeopathic agent.Type: ApplicationFiled: May 23, 2011Publication date: November 29, 2012Inventors: Ned L. Jensen, Peter E. Fuller
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Publication number: 20120282339Abstract: The invention relates to compositions for use in purgatives, to purgatives comprising such compositions, and to methods for inducing purgation of the colon. The composition may comprise at least one water-soluble sodium salt; at least one water-soluble minimally degradable sugar in an amount, by weight, of from about 1 to about 3 times the weight of sodium ions in said composition; at least one water-soluble potassium salt in an amount, by weight, of from about 0.05 to about 1 time the weight of said sodium salt in said composition; and at least one water-soluble magnesium salt, wherein the weight of magnesium ions in said composition is from 0.1 to about 10 times the weight of sodium ions in said composition.Type: ApplicationFiled: June 29, 2012Publication date: November 8, 2012Inventors: Thomas Julius BORODY, Sanjay RAMRAKHA, John SAXON, Anthony WETTSTEIN
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Publication number: 20120244231Abstract: The present invention relates to a potassium chloride composition comprising an iron complex of tartaric acid, characterized in that at least 5% by weight of the tartaric acid is mesotartaric acid and that a 10% by weight aqueous solution of said potassium chloride composition has a pH value of between 6 and 11. The present invention furthermore relates to a process to prepare such a potassium chloride composition and to the use of such a potassium chloride composition.Type: ApplicationFiled: November 29, 2010Publication date: September 27, 2012Inventors: Shanfeng Jiang, Hendrikus Wilhelmus Bakkenes, Roberto Aloysius Geradrdus Maria Bergevoet, Johannes Albertus Maria Meijer, Maria Steensma
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Patent number: 8273380Abstract: A beverage for minimizing or reducing jet lag symptoms preferably includes vitamin B3, vitamin B5, vitamin B6, vitamin B12, vitamin D, zinc, calcium, iodine, magnesium, manganese, ginseng, ginkgo biloba, grape seed extract, Echinacea extract and water. A method for minimizing or reducing jet lag symptoms including ingestion of the beverage by a traveler, one hour prior to a flight, and/or during the flight, and/or after a flight.Type: GrantFiled: May 19, 2009Date of Patent: September 25, 2012
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Patent number: 8273378Abstract: Dialysis solutions comprising pyrophosphates and methods of making and using the dialysis solutions are provided. In an embodiment, the present disclosure provides a dialysis solution comprising a stable and therapeutically effective amount of pyrophosphate. The dialysis solution can be sterilized, for example, using a technique such as autoclave, steam, high pressure, ultra-violet, filtration or combination thereof. The dialysis solution can be in the form of a concentrate.Type: GrantFiled: January 14, 2010Date of Patent: September 25, 2012Assignees: Baxter International, Inc., Baxter Healthcare S.A.Inventors: Bruce L. Riser, Paul Zieske, Sujatha Karoor, Himanshu D. Patel
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Publication number: 20120195860Abstract: The present invention relates to a latent neural stem cell population which is capable of activation by membrane depolarization of a neural cell population, isolation and culture of same, and uses thereof.Type: ApplicationFiled: April 10, 2008Publication date: August 2, 2012Inventors: Tara Louise Walker, Perry Francis Bartlett
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Patent number: 8216172Abstract: A multi-part substitution infusion fluid for an extracorporeal blood treatment and methods for using same are provided. Generally, the multi-part substitution fluid comprises a first solution composed of electrolytes but without divalent cations and a second solution comprising divalent cations. Another embodiment includes a third solution comprising a matching citrate/citric acid anticoagulant. The described methods of using the multi-part substitution infusion fluids significantly reduce risks associated with various extracorporeal blood treatments.Type: GrantFiled: November 2, 2011Date of Patent: July 10, 2012Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Peter C. Chang, Jean-Michel Lannoy
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Publication number: 20120135090Abstract: The invention provides a solution in water comprising the following components at the following concentrations: (a) N×(70 to 130) g/L polyethylene glycol (PEG) having an average molecular weight of 2500 to 4500; (b) N×(1.6 to 4.0) g/L sodium chloride; (c) N×(0.2 to 0.6) g/L potassium chloride; (d) N×(0.6 to 2.2) g/L sodium bicarbonate; (e) N×an amount of preservative; (f) optionally N×an amount of flavouring; and (g) optionally N×an amount of sweetener where N is in the range of 2 to 8. The solution is a concentrate for dilution. In use it is diluted N-fold with water to provide a solution for administration to a subject for the treatment of constipation or faecal impaction. Also provided are solutions, kits, unit doses and methods that comprise or use the solutions.Type: ApplicationFiled: July 30, 2010Publication date: May 31, 2012Inventors: Chris Seldon, Dawn Padfield, Frances Morrissey
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Publication number: 20120107419Abstract: A formulation and method of use for neutralizing the acidity in the mouth of a patient. The method comprises taking into the mouth an aqueous solution comprising a water soluble inorganic salt consisting of sodium and/or potassium chloride, a sodium phosphate buffer consisting of sodium monophosphate and/or sodium diphosphate and glycerin in a pH-balanced solution, maintaining the aqueous solution in the mouth for a period of time sufficient to reduce the acidity in the mouth, and thereafter spitting out the aqueous solution. The amount of sodium/potassium chloride present in the aqueous solution may be from about 0.45% to about 2.0% by weight per unit volume. The amount of sodium monophosphate in the aqueous solution may be from about 0.005% to about 0.02% by weight per unit volume, for example. The amount of sodium diphosphate in the aqueous solution may be from about 0.005% to about 0.02% by weight per unit volume. The amount of glycerin in the aqueous solution may be about 0.0005% to about 0.Type: ApplicationFiled: October 28, 2010Publication date: May 3, 2012Inventor: Raj Sadasivan
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Patent number: 8158157Abstract: A multi-part substitution infusion fluid for an extracorporeal blood treatment and methods for using same are provided. Generally, the multi-part substitution fluid comprises a first solution composed of electrolites but without divalent cations and a second solution comprising divalent cations. Another embodiment includes a third solution comprising a matching citrate/citric acid anticoagulant. The described methods of using the multi-part substitution infusion fluids significantly reduce risks associated with various extracorporeal blood treatments.Type: GrantFiled: July 7, 2010Date of Patent: April 17, 2012Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Peter C. Chang, Jean-Michael Lannoy
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Publication number: 20120034320Abstract: The present invention comprises an all-natural composition of matter and methods of delivering nutrients, medicines, pain relievers, antioxidants, antidotes, antibiotics and various active ingredients and supplements directly to the affected area of the body. The all-natural carrier composition consists essentially of the combination of a natural oil, water, salt(s), natural emulsifier, natural sugar(s), plant extracts, natural acid(s), starch and natural flavor(s). The active substances that are mixed with the all-natural carrier composition, include, but are not limited to, drugs, vitamins, minerals, antibiotics anti fungal agents, antioxidants, diuretics, allergy medicines, anti-inflammatory agents, muscle relaxers, pain reducers, diabetic drugs, neuropathy drugs, chemotherapy agents, arthritis drugs, lotions for eczema, shingles, psoriasis, skin rash; herbal medicines, erectile dysfunction drugs, hormones, cholesterol drugs, essential fatty acids, and the like.Type: ApplicationFiled: July 15, 2011Publication date: February 9, 2012Applicant: DOMINION RESOURCES, UNLIMITED, LLCInventors: Daniel G. Murray, Michael W. McDonough
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Publication number: 20110293747Abstract: The field of colonic diagnostic and surgical procedures is hampered by the lack of optimal means available to cleanse the colon. A compromise between convenient, distasteful, solid or low volume, hyperosmotic solutions which cause considerable fluid and electrolyte imbalances in patients and large volume, difficult to consume, iso-osmotic solutions has had to be made heretofore. This invention describes a low volume, hyper-osmotic solution consisting of sulfate salts with and with out polyethylene glycol, and further comprising a sweetener and/or flavoring. Unlike prior art, this composition is useful for the cleansing of the bowel and, in lower volumes, as a laxative, without producing clinically significant changes in bodily function.Type: ApplicationFiled: August 10, 2011Publication date: December 1, 2011Applicant: BRAINTREE LABORATORIES, INC.Inventor: Mark V. CLEVELAND
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Publication number: 20110244055Abstract: The present invention relates to a method of suppressing appetite or promoting a stimulant effect in an individual in need thereof, comprising administering to the individual per 24 hour period an effective amount of one or more alkali metals selected from the group consisting of one or more sources of cesium, one or more sources of rubidium, one or more sources of lithium, and combinations thereof. The present invention further relates to weight loss or stimulant compositions comprising one or more alkali metals.Type: ApplicationFiled: March 30, 2011Publication date: October 6, 2011Inventor: Arnold Forbes
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Publication number: 20110223252Abstract: The invention relates to compositions for use in purgatives, to purgatives comprising such compositions, and to methods for inducing purgation of the colon. The composition may comprise at least one water-soluble sodium salt; at least one water-soluble minimally degradable sugar in an amount, by weight, of from about 1 to about 3 times the weight of sodium ions in said composition; at least one water-soluble potassium salt in an amount, by weight, of from about 0.05 to about 1 time the weight of said sodium salt in said composition; and at least one water-soluble magnesium salt, wherein the weight of magnesium ions in said composition is from 0.1 to about 10 times the weight of sodium ions in said composition.Type: ApplicationFiled: May 19, 2011Publication date: September 15, 2011Inventors: Thomas Julius BORODY, Sanjay RAMRAKHA, John SAXON, Antony WETTSTEIN
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Patent number: 7993682Abstract: The invention relates to compositions for use in purgatives, to purgatives comprising such compositions, and to methods for inducing purgation of the colon. The composition may comprise at least one water-soluble sodium salt; at least one water-soluble minimally degradable sugar in an amount, by weight, of from about 1 to about 3 times the weight of sodium ions in said composition; at least one water-soluble potassium salt in an amount, by weight, of from about 0.05 to about 1 time the weight of said sodium salt in said composition; and at least one water-soluble magnesium salt, wherein the weight of magnesium ions in said composition is from 0.1 to about 10 times the weight of sodium ions in said composition.Type: GrantFiled: March 4, 2003Date of Patent: August 9, 2011Inventors: Thomas Julius Borody, Sanjay Ramrakha, John Saxon, Antony Wettstein
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Publication number: 20110189091Abstract: The present invention provides compositions, systems, kits, and methods for preparation prior to a colonoscopy or other gastrointestinal procedure. In particular, the present invention provides a colon lavage system comprising an aqueous portion and a solid portion.Type: ApplicationFiled: April 20, 2010Publication date: August 4, 2011Inventor: Dale R. Bachwich
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Publication number: 20110183010Abstract: The present invention relates to a cardioplegic preparation. According to a preferred embodiment of the invention, the preparation is made of two solutions, the first containing magnesium sulfate, potassium and xylitol, and the other containing procaine.Type: ApplicationFiled: August 10, 2009Publication date: July 28, 2011Inventors: Erich Gygax, Thierry Carrel, Hendrik Tevaearai