Calcium Containing Sulfur Compound (e.g., Calcium Sulfate, Etc.) Patents (Class 424/696)
  • Patent number: 6254893
    Abstract: A calcium-based ophthalmic composition for treating dry eye including a hydrophobic carrier, such as petrolatum, and a calcium salt. Also a method for treating dry eye comprising the step of administering the composition according to the present invention.
    Type: Grant
    Filed: October 23, 1998
    Date of Patent: July 3, 2001
    Assignee: DEO Corporation
    Inventor: Donald L. MacKeen
  • Patent number: 6235317
    Abstract: An additive for stimulants, useful in particular to reduce the health-damaging effects of coffee beverages, contains one or several vitamins, dandelion root extract, and, if required, one or several mineral salts. The additive characterized in that it contains anise extract and adenosine.
    Type: Grant
    Filed: June 16, 1999
    Date of Patent: May 22, 2001
    Inventors: György Pintz, Kinga Paczolay
  • Patent number: 6203823
    Abstract: Use of calcium taurate as an antihypertensive agent and dietary supplement. The compound is prepared by reacting taurine and calcium in a 2:1 molar ratio. The resulting mixture is diluted with alcohol and the remaining clear filtrate is crystallized. Calcium taurate is taken orally as a nutritional supplement or antihypertensive agent, and can be used as an adjuvant to conventional antihypertensive drugs.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: March 20, 2001
    Assignee: Nutrition 21
    Inventor: Mark F. McCarty
  • Patent number: 6197815
    Abstract: Metal amino acid chelates for animals are beneficial for facilitating and promoting growth by increasing desired metallic ion uptake. The present invention is directed to a process for providing an animal fed additive by preparing metal amino acid chelates, and the metal amino acid chelate growth facilitator, promoter and enhancer prepared by the process.
    Type: Grant
    Filed: March 18, 1998
    Date of Patent: March 6, 2001
    Assignee: J.H. Biotech, Inc.
    Inventor: Hsinhung John Hsu
  • Patent number: 6099869
    Abstract: Use of calcium taurate as an antihypertensive agent and dietary supplement. The compound is prepared by reacting taurine and calcium in a 2:1 molar ratio. The resulting mixture is diluted with alcohol and the remaining clear filtrate is crystallized. Calcium taurate is taken orally as nutritional supplement or antihypertensive agent, and can be used as an adjuvant to conventional antihypertensive drugs.
    Type: Grant
    Filed: December 15, 1998
    Date of Patent: August 8, 2000
    Assignee: Nutrition 21
    Inventor: Mark F. McCarty
  • Patent number: 6093423
    Abstract: A chemical agent for use in binding to and insolubilizing the solubilized products of fat digestion in order to prevent absorption of fat from the diet.
    Type: Grant
    Filed: April 25, 1997
    Date of Patent: July 25, 2000
    Assignee: Kappa Pharmaceuticals Limited
    Inventor: Alun Roy Williams
  • Patent number: 6060086
    Abstract: The invention relates to a method of using recovered drywall to achieve an effect in an animal habitat. The method includes applying an amount of recovered drywall to surfaces of the habitat, the effect achieved being reduction or control of bacterial count, fly population, odor or combinations thereof.
    Type: Grant
    Filed: May 15, 1997
    Date of Patent: May 9, 2000
    Assignee: Gypsum Recycling, Inc.
    Inventors: Ted Belanus, James Kramer
  • Patent number: 5958464
    Abstract: A composition for preventing and treating milk fever in freshening cows, and a method of administering the composition. The basic composition is a mixture of water, calcium chloride, propylene glycol, B vitamins and minerals. The calcium content is lower than conventional calcium treatments used for this purpose. The propylene glycol gives the cow an energy boost and sweetens the taste so the cow does not object to it as it does to conventional gels and liquids. The B vitamins stimulate the cow's appetite. The minerals replace minerals lost in the milk and also help the cow absorb calcium. The composition of the present invention is in a liquid form and is preferably administered using a 200-300 cc drench gun. The end of the dispensing tube of the drench gun is placed between the teeth and cheek of the cow near the receptors that stimulate the esophageal groove reflex.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: September 28, 1999
    Inventor: Jack W. Register
  • Patent number: 5942255
    Abstract: The invention is directed to a method of enhancing lean tissue mass in a subject by administering calcium to the subject, thereby enhancing the lean tissue mass in the subject. The invention is also directed to a method of enhancing bone mineral content in a physically active subject comprising administering calcium to the subject, thereby enhancing the bone mineral content in the subject. The invention is also directed to a method of enhancing bone mineral content and of enhancing lean tissue mass in a subject comprising administering calcium to the subject, thereby enhancing the bone mineral content and enhancing the lean tissue mass in the subject. The invention is further directed to a milk-free composition for enhancing bone mineral content and/or for enhancing lean tissue mass in a physically active subject, comprising an effective amount of calcium.
    Type: Grant
    Filed: July 15, 1996
    Date of Patent: August 24, 1999
    Assignee: The University of Memphis
    Inventor: Robert C. Klesges
  • Patent number: 5919491
    Abstract: This invention relates to a hydrophilic matrix containing a pharmaceutically acceptable calcium source for use as a calcium supplement for mammals.
    Type: Grant
    Filed: November 12, 1996
    Date of Patent: July 6, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Prasad S. Adusumilli, Vimala Sivapragasam
  • Patent number: 5914135
    Abstract: Calcium carbonate liquid antacid compositions containing one or more pH adjusting agents to maintain the pH above 9.0, preferably above 9.5. The resultant antacid liquid possesses superior resistance to microbial attack and enhanced taste properties.
    Type: Grant
    Filed: April 16, 1997
    Date of Patent: June 22, 1999
    Assignee: McNeil-PPC, Inc.
    Inventors: John J. Dubek, Gerard P. McNally, Bruce P. Smith
  • Patent number: 5830508
    Abstract: A calcium-based ophthalmic composition for treating dry eye is disclosed. The composition includes a hydrophobic carrier such as petrolatum and a calcium salt. The composition can further include a polyol such as glycerol, and an agent such as anhydrous lanolin, to enhance the interface between the carrier, and the calcium salt and polyol. Also disclosed is a method for treating dry eye comprising the step of administering the composition according to the present invention by placing the composition on the lateral portion of the lower eyelid margin. This method allows the composition to gradually disperse onto the cornea and conjunctiva.
    Type: Grant
    Filed: January 21, 1997
    Date of Patent: November 3, 1998
    Assignee: Deo Corporation
    Inventor: Donald L. MacKeen
  • Patent number: 5776503
    Abstract: The present invention provides a dialysis solution that contains amino acids for treating and/or preventing malnutrition in a peritoneal dialysis patient. The amino acid composition is optimized to minimize metabolic acidosis while normalizing amino acid plasma profiles.
    Type: Grant
    Filed: July 24, 1997
    Date of Patent: July 7, 1998
    Assignee: Baxter International Inc.
    Inventors: Leo Martis, Michael R. Jones
  • Patent number: 5756127
    Abstract: A bioresorbable string of implantable beads in which the beads consist essentially of calcium sulfate and a quantity of a drug suitable for treating tissue disorders, and in which both the beads and the line that joins the beads together are bioresorbable.
    Type: Grant
    Filed: October 29, 1996
    Date of Patent: May 26, 1998
    Assignee: Wright Medical Technology, Inc.
    Inventors: Bernard F. Grisoni, Steve Gitelis, Timothy L. Harrison, Jack E. Parr, Ben R. Shappley
  • Patent number: 5698230
    Abstract: The present invention provides a dialysis solution that contains amino acids for treating and/or preventing malnutrition in a peritoneal dialysis patient. The amino acid composition is optimized to minimize metabolic acidosis while normalizing amino acid plasma profiles.
    Type: Grant
    Filed: March 24, 1997
    Date of Patent: December 16, 1997
    Assignee: Baxter International Inc.
    Inventors: Leo Martis, Michael R. Jones
  • Patent number: 5683725
    Abstract: Modulation of substance P by compounds containing calcium sulfate is disclosed. Preferred calcium sulfate compounds include syngenite, gorgeyite and gypsum. Methods of this invention include the modulation of substance P, as well as methods for preventing or treating conditions associated with substance P, by administering to an animal an effective amount of a calcium sulfate compound. Conditions associated with substance P include headaches and migraine, neurogenic inflammation, emesis, nausea and vomiting, cough and bronchitis, obesity, allergy, asthma, hemorrhoids and anal fissures, ulcer, fever, infertility and periodontal disease.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: November 4, 1997
    Assignee: BioFrontiers, Inc.
    Inventors: Sohail Malik, Rolland F. Hebert, Min Yee
  • Patent number: 5648097
    Abstract: A novel method of producing biodegradable microparticles is disclosed. Inorganic calcium salts are mixed with water to form a slurry. The slurry is then added to an oil bath which is then mixed to form an emulsion. The mixing continues for a period of time sufficient to form hardened microparticles. The hardened microparticles are then retrieved and characterized. Biologically active agents may be added to the slurry prior to emulsification, or they may be added to the hardened microparticles after production. The microparticles may be injected into a human being whereby they act as controlled release drug delivery vehicles.
    Type: Grant
    Filed: October 4, 1995
    Date of Patent: July 15, 1997
    Assignee: Biotek, Inc.
    Inventor: Elie S. Nuwayser
  • Patent number: 5616324
    Abstract: A synergistic mixture particularly suitable for the treatment of animals whic consists of at least two of the group consisting of DL.Phenylalanine, Ruta Graveolans and Corydali Bulbosa together with a carrier to make up a required volume, the mixture having a pro-inflammatory effect which accelerates the healing process of inflammation. It is preferred that there is provided mixture of DL.Phenylalanine with one product selected from the group of Ruta Graveolans and Corydalis Bulbosa. In a specific form, the mixture also includes Nicotinic Acid.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: April 1, 1997
    Inventors: Antoinette Foster, Don Foster
  • Patent number: 5612061
    Abstract: A composition for the treatment of premenstrual syndrome comprising an effective amount of calcium, magnesium, an analgesic and a diuretic sufficient to reduce the symptoms of premenstrual syndrome.
    Type: Grant
    Filed: October 14, 1994
    Date of Patent: March 18, 1997
    Inventor: Simon W. Rabkin
  • Patent number: 5599561
    Abstract: A method of making poultice by mixing together water, fine mineral powder, vinegar, herbal liniment solution, and hydrated magnesium sulfate (also known as Epsom salt) to produce a poultice capable of being applied to muscles, joints, or both which may be sore, injured, or both.
    Type: Grant
    Filed: August 4, 1995
    Date of Patent: February 4, 1997
    Inventor: Angel Gonzalez, Jr.
  • Patent number: 5595764
    Abstract: An ophthalmologic composition therapeutic in the treatment of dry eye syndrome is disclosed. The composition is comprised of a minimally soluble salt of calcium that has been finely divided into particles having a mean diameter of 10 to 60 microns. The calcium salt particles are suspended within a pharmacologically acceptable carrier such as petrolatum or physiological saline. The composition is delivered to the ocular surface in an amount and for a time sufficient to alleviate the symptoms of dry eye.
    Type: Grant
    Filed: October 28, 1993
    Date of Patent: January 21, 1997
    Assignee: DEO Corporation
    Inventor: Donald L. Mackeen
  • Patent number: 5520922
    Abstract: There are provided formable compositions which comprise:(A) 25 to 80% by weight of a glass ionomer cement, containing (a) an aluminum fluorosilicate glass, (b) at least one polymeric polyacid with an average molecular weight >500, (c) water and (d) optionally a chelating agent;(B) and 20 to 75% by weight of a fluoride and/or oxide and/or mixed fluoride and/or mixed oxide of heavy metal elements which are essentially insoluble at ambient temperatures in an aqueous solution containing the polymeric polyacid and/or an aqueous solution containing the chelating agent.The compositions are especially well suited as filling materials for dental root canals.
    Type: Grant
    Filed: October 18, 1994
    Date of Patent: May 28, 1996
    Assignee: THERA Patent GmbH & Co. KG, Gesellschaft fur industrielle Schutzrechte
    Inventors: Oswald Gasser, Rainer Guggenberger
  • Patent number: 5487894
    Abstract: A dietary supplement composition is disclosed which contains dehydrated mung bean sprout and beta-glucan enriched oat groat.
    Type: Grant
    Filed: December 19, 1994
    Date of Patent: January 30, 1996
    Inventor: Joseph Kovacs
  • Patent number: 5472699
    Abstract: A method for reducing the visible size of facial skin pores by applying a novel composition which comprises an oil absorbing powder, a botanical astringent and a biological compound that alters the structure of the skin and/or the function of the sebaceous glands.
    Type: Grant
    Filed: January 27, 1995
    Date of Patent: December 5, 1995
    Assignee: Avon Products, Inc.
    Inventors: John A. Duffy, Alexander P. Znaiden
  • Patent number: 5425945
    Abstract: Agglomerated psyllium husk comprising edible acid uniformly dispersed throughout the agglomerating coating. Preferred are maltodextrin-containing agglomerates of psyllium husk comprising citric acid uniformly dispersed throughout the maltodextrin coating. This agglomerated psyllium husk has improved mixability and dispersibility in liquids.
    Type: Grant
    Filed: March 14, 1994
    Date of Patent: June 20, 1995
    Assignee: The Procter & Gamble Company
    Inventor: Melvin A. Barbera
  • Patent number: 5395622
    Abstract: A preparation for the prevention or treatment of hypocalcemia in ruminants is prepared by forming a homogeneous mixture of CaCl.sub.2.xH.sub.2 O and CaSO.sub.4.yH.sub.2 O, x being a number greater than 0 and lower than 6 and y being a number equal to or greater than zero and lower than or equal to 2, at a weight ratio of 1:0.05 to 1:2.4, adding water to the mixture to convert the ingredients to CaCl.sub.2.6H.sub.2 O and CaSO.sub.4.2H.sub.2 O, introducing the mixture into molds, and heating the molds so that the mixture solidifies.
    Type: Grant
    Filed: February 25, 1993
    Date of Patent: March 7, 1995
    Assignee: Boehringer Ingelheim Agrovet A/S
    Inventor: Leif H. Nielsen
  • Patent number: 5366739
    Abstract: A method for prolonged delivery of a therapeutic agent to the eye is disclosed. The method provides for the addition of a desired drug to a suitable, preferably non-aqueous, vehicle. An amount of the vehicle containing a therapeutic dose of the drug is placed on the extraocular skin adjacent to the lateral canthus of the eye. Movements of the orbicularis oculi associated with the scissor-like closing of the lids of the eye continuously transport small portions of the drug containing vehicle into the interpalpebral space where the drug is released to the cornea for intraocular penetration and treatment effected. The method of the invention is particularly effective in delivering insoluble calcium salts for the treatment of dry eye.
    Type: Grant
    Filed: December 19, 1992
    Date of Patent: November 22, 1994
    Assignee: DEO Corporation
    Inventor: Donald L. MacKeen
  • Patent number: 5358722
    Abstract: Ferritin analogs comprising an apoferritin protein shell and a core substantially devoid of ferrihydrite, e.g. of inorganic composition such as aluminum hydroxide or organic composition such as acetaminophen. The protein shell can be removed from ferritin analog to produce spherules having a substantially monomodal nominal diameter between about 45 and 90 Angstroms.
    Type: Grant
    Filed: January 25, 1993
    Date of Patent: October 25, 1994
    Assignee: Monsanto Company
    Inventor: Bruce F. Monzyk
  • Patent number: 5342629
    Abstract: Cellulosic particles, for example wood particles, stored in a pile are preserved by contacting the particles with a thiocarbonate composition.
    Type: Grant
    Filed: June 28, 1991
    Date of Patent: August 30, 1994
    Assignee: Union Oil Company of California
    Inventors: Roger A. Brown, Richard L. Pilling, Donald C. Young
  • Patent number: 5322698
    Abstract: The invention relates to a process for the preparation of a tablet or dragee composition containing a moisture-, heat- and light-sensitive compounds having monoclinic crystalline structure as active ingredients, which comprises homogenizing the active ingredient with 0.2 to 1.5 parts by weight of an anhydrous alkaline earth metal salt and 0.5 to 2.5 parts by weight of microcrystalline cellulose calculated for the active ingredient and optionally with one or more pharmaceutically acceptable carrier(s) and/or additive(s) and compressing the homogeneous mixture obtained to tablets in a manner known per se and, if desired, coating the tablet thus obtained in a manner known per se.
    Type: Grant
    Filed: June 5, 1992
    Date of Patent: June 21, 1994
    Assignee: Biogal Gyogyszergyar Rt.
    Inventors: Istvan Kovacs, Katalin Beke, Tibor Mathe, Judit Szilagyi, Gyorgy Bacsa, Katalin Marossy, Sandor Jancso, Levente Szendrei, Erno Orban, Margit Simo, Margit Biblo, Dorottya Bobak, Jozsef Lango
  • Patent number: 5290572
    Abstract: An ophthalmologic composition therapeutic in the treatment of dry eye syndrome is disclosed. The composition is comprised of a minimally soluble salt of calcium that has been finely divided into particles having a mean diameter of 10 to 60 microns. The calcium salt particles are suspended within a pharmacologically acceptable carrier such as petrolatum or physiological saline. The composition is delivered to the ocular surface in an amount and for a time sufficient to alleviate the symptoms of dry eye.
    Type: Grant
    Filed: August 6, 1992
    Date of Patent: March 1, 1994
    Assignee: DEO Corporation
    Inventor: Donald L. MacKeen
  • Patent number: 5281265
    Abstract: A new surgical cement is disclosed. This surgical cement comprises a hardened cement formed from a mixture comprising a cementing component selected from the group consisting of calcium components having a solubility in water at 25.degree. C. in the range of about 0.5 .times. 10.sup.-2 M to about 20 .times. 10.sup.-2 M and mixtures thereof; a setting component selected from the group consisting of water soluble salts of polyfunctional carboxylic acids containing 2 to about 10 carbon atoms, water soluble dibasic phosphate salts and mixtures thereof; and water in an amount effective to form a paste from the mixture which paste hardens into said hardened cement which is biocompatible.
    Type: Grant
    Filed: February 3, 1992
    Date of Patent: January 25, 1994
    Inventor: Sung-Tsuen Liu
  • Patent number: 5232698
    Abstract: Psyllium husk-containing drink mix compositions comprising small particle size psyllium husk and edible, water soluble salts. The edible, water soluble salts are present at a level sufficient to reduce the gellation rate of the psyllium husk when dispersed in an aqueous solution.
    Type: Grant
    Filed: June 12, 1992
    Date of Patent: August 3, 1993
    Assignee: The Proctor & Gamble Company
    Inventor: Lee A. Hord
  • Patent number: 4915936
    Abstract: Gingivitis and related periodontal problems of the gingival tissues may be treated with a dental hygiene composition comprising an effective amount of a calcium sulfate compound such as calcium sulfate hemihydrate. Preferred compositions comprise mouthwashes and oral rinses containing about 5-90% by weight of calcium sulfate hemihydrate, a liquid carrier such as water, a humectant and an alcohol.
    Type: Grant
    Filed: October 31, 1988
    Date of Patent: April 10, 1990
    Assignee: United States Gypsum Company
    Inventors: Lloyd D. Patterson, Jay W. Palmer