Abstract: Wrinkles are improved by applying an oral preparation, injection preparation or external skin preparation having a substance that controls heparanase as an active ingredient thereof.

Abstract: A composition for treating damaged tissue and promoting healthy tissue growth, healing and tissue regeneration, wherein said composition comprises an extracellular matrix compound, a surface-active lipid, one or more enantioinerically pure L-amino acids or glycine, a hydrophilic surfactant with a high HLB, as well as vitamins, minerals or trace elements. Not only does it maintain good health, but the components are non-intrusive, bio-safe, non-coalescent and can mimic normally occurring stem-cells within a body. When applied to diseased tissues, the subject compositions can stimulate, facilitate, and accelerate protein synthesis for the regeneration of diseased organs and tissues. The healing efficacy of these tissue components gives us further appreciation of the protective action of human tissue over and above and other than the immune protective system or perhaps an integral component part of the immune system.

Abstract: Provided an acidic liquid preparation containing a herb and/or animal-origin extract at high concentration to suppress time-dependent occurrence of precipitation and/or opacity. A liquid preparation containing a herb-origin extract having pH of 3.0 to 5.5 and containing the herb-origin extract at a concentration of 5 to 50 w/v % (dry weight) to the total amount of the liquid preparation, containing a caramel at a concentration of 0.5 to 20 w/v % to the total amount of the liquid preparation, wherein the caramel has isoelectric point of 2.5 to 4.0 and 1.0 w/v % aqueous solution of the caramel has pH of 4.5 to 6.0. A liquid preparation containing an animal-origin extract having pH of 3.0 to 5.5 and containing the animal-origin extract at concentration of 5 to 50 w/v % (dry weight) to the total amount of the liquid preparation, containing a caramel at concentration of 0.5 to 20 w/v % to the total amount of the liquid preparation, wherein the caramel has isoelectric point of 0.5 to 4.0 and 1.

Abstract: Time release repellent formulations and methods of making formulations, comprising a natural repellent, alum in an amount effective to keep microbial count below a pre-determined level and a natural binder. The natural repellent may be animal urine or a natural oil. The natural binder is selected from the group consisting of: rice, pearlite, polymer, peat moss, clay and foam. The pH level of the formulation is maintained within a pre-determined range by adding a natural acid to lower the pH level or adding a natural base to raise the pH level.

Abstract: The invention relates to a novel agent containing fat (oil), which contains onion extract, in addition to the production and use thereof for caring, preventing or treating damaged skin tissue, such as after operations, biopsies, wounds, burns and other accidents, and especially scarred tissue, stretch marks, degenerative skin conditions and others. The agent is characterised in that the base thereof is based on oil, which can be used to produce, for example, cream, lotion, fluid, massage, or balm based products which contain fail (oil). Surprisingly, the onion extract, which contains water, alcohol or water-alcohol, can be integrated into a base containing oil without the effectiveness thereof being reduced or a phase separation being produced. The effectiveness thereof could be proved when the medical application thereof was monitored.

Abstract: Provided are a composition and method of increasing health of the human body includes placing a composition inside a solution jar of a solution jar assembly, wherein the composition comprises at least one of a garlic solution comprising garlic extract, ethanol, and water; a 10-undecenoic acid solution comprising 10-undecenoic acid and at least one of water and alcohol; and a Pau d'Arco solution comprising Pau d'Arco extract, corn starch, ethanol, and water, wherein the solution jar assembly includes a device comprising either a radial appliance or a wet-cell battery appliance; a first metal disc connected to the device by a first wire; a solution jar, connected to the device by a second wire, for holding the solution; a second metal disc connected to the solution jar by a third wire; and a connecting loop, located inside a removable lid of the solution jar, connecting the first and third wires and passing through the solution; wherein if the device is the radial appliance, placing the radial appliance in a co

Abstract: The present invention relates to a composition for promoting the growth of animals, comprising extracts of Artemisia capillaris thunberg, Acanthopanax and garlic, as well as a feed composition comprising the same. The composition for promoting the growth of animals shows the excellent effect of promoting the secretion of growth hormone. Particularly, when the feed composition comprising the animal growth-promoting composition is administered to livestock animals, it will show the excellent effects of body weight gain, meat quality improvement and milk production increase in the livestock animals.

Abstract: Herbal compositions are useful for inhibition, amelioration or prevention of adipogenesis mediated diseases such as obesity, lipid storage disease and hyperlipemia. The herbal compositions comprise biologically effective amounts of extracts or fractions from Piper betle in combination with one or more of the extracts or fractions derived from Dolichos biflorus, Commiphora mukul, Boerhaavia diffusa, Tribulus terrestris and Zingiber officinale as active ingredients. The compositions optionally contain a bio-enhancing agent or a bio-protecting agent, along with biologically acceptable carriers or diluents. The herbal compositions may be used in a method for treating or preventing adipogenesis involved diseases in mammals.

Abstract: The present invention discloses the extracts of Holoptelea integrifolia or the purified fractions isolated there from and the dietary, nutraceutical and pharmaceutical compositions comprising the same or optionally in combination with one or more known anti-obesic agents useful for the purpose of inhibition, amelioration or prevention of adipogenesis and lipolysis involved diseases. The invention further discloses a method for treating or preventing obesity and adipogenesis and lipolysis involved diseases using the compositions containing the extracts of purified fractions of Holoptelea integrifolia.

Abstract: Disclosed herein is a natural oriental medicinal composition for the promotion of hair growth. The oriental medicinal composition comprises a black bean extract, a tangerine extract, a potato extract, a pine needle extract and a quartzite powder. Since the oriental medicinal composition comprises crude drugs extracted from natural substances that can prevent hair loss, it is effective for hair growth and has ensured biostability. Particularly, the oriental medicinal composition allows newborn hair to grow in the form of stiff hair.

Abstract: There are provided various compounds and compositions comprising polyunsaturated fatty acid monoglycerides and derivatives thereof. These compounds and compositions can be useful as cancer chemopreventive agents. They can also be useful for enhancing solubility of various active agents and enhancing their bioavailability.

Abstract: A composition for the control of nematodes consisting of salicylaldehyde and a surfactant. Garlic extract added to the salicylaldehyde provides a composition that demonstrates a more potent control action against potato cyst nematodes.

Abstract: The invention discloses 5-lipoxygenase inhibitory product prepared from botanical sources. More specifically, the invention describes 5-lipoxygenase inhibitory extracts or bio-enriched extracts or fractions of Aphanamixis polystachya, methods of making 5-lipoxygenase inhibitory extract, and methods of treating and/or preventing disease conditions mediated by 5-lipoxygenase by using the said extract. The invention further discloses pharmaceutical or nutraceitical or dietary compositions containing therapeutically effective amounts of the extracts of Aphanamixis polystachya in combination with other known anti-inflammatory agents useful for oral, parenteral and topical administration.

Abstract: The present invention relates to an antibacterial composition including a fermented garlic solution that is fermented by lactic acid bacteria. More specifically, it provides an antibacterial substance active against gram-positive and gram-negative bacteria, yeast, and antibiotic-resistant bacteria. An antibacterial composition according to the present invention that includes a fermented garlic solution that is fermented by lactic acid bacteria as an active ingredient controls the growth of bacteria or fungi, and is thereby able to prevent and treat infections thereof.

Abstract: Gastric resistant film-forming compositions are described herein. The composition comprises a gastric resistant natural polymer, a film-forming natural polymer, and optionally a gelling agent. Suitable gastric resistant natural polymers include polysaccharides such as pectin and pectin-like polymers. The film-forming composition can be used to prepare soft or hard shell gelatin capsules which can encapsulate a liquid or semi-solid fill material or a solid tablet (Softlet®) comprising an active agent and one or more pharmaceutically acceptable excipients. Alternatively, the composition can be administered as a liquid with an active agent dissolved or dispersed in the composition. The compositions are not only gastric resistant but may also prevent gastric reflux associated with odor causing liquids, such as fish oil or garlic oil, encapsulated in a unit dosage form and esophageal irritation due to the reflux of irritant drugs delivered orally.

Abstract: An antiviral substance including a fermentation product of garlic that is fermented by lactic acid bacteria is provided. More specifically, an antiviral agent including a fermentation product of garlic, that is fermented by lactic acid bacteria, as an active ingredient is provided. The antiviral agent including a fermentation product of garlic fermented by lactic acid bacteria is useful as a preventing or treating agent of viral infection by inhibiting viruses.

Abstract: An antiviral substance including a fermentation product of garlic that is fermented by lactic acid bacteria is provided. More specifically, an antiviral agent including a fermentation product of garlic, that is fermented by lactic acid bacteria, as an active ingredient is provided. The antiviral agent including a fermentation product of garlic fermented by lactic acid bacteria is useful as a preventing or treating agent of viral infection by inhibiting viruses.

Abstract: Cleaning and disinfecting compositions containing one or more “green” surfactants are disclosed. The compositions may be present as micro-emulsions that generally include green disinfecting agents, green surfactants, and water. The composition may also contain other green ingredients such as linkers, pH adjusting agents, natural fragrances, natural insecticides, and other natural organic actives such as natural oils. The composition may be used as a green cleaning and disinfecting composition with performance comparable or superior to conventional cleaning and disinfecting products with less desirable ecological profiles.

Abstract: A natural oriental medicinal composition for the promotion of hair growth is provided. The oriental medicinal composition includes a black bean extract, a tangerine extract, a potato extract, a pine needle extract and a quartzite powder. Since the oriental medicinal composition includes crude drugs extracted from natural substances that can prevent hair loss, it is effective for hair growth and has ensured biostability. Particularly, the oriental medicinal composition allows newborn hair to grow in the form of stiff hair.

Abstract: A new Animal Repellent & Method of Use Thereof which generally comprises a composition of materials or ingredients that combine to create a new and novel animal repellant that is embodied in liquid or granular form, and can be applied as a spray directly to plant parts or sprinkled on or combined with the soil or mulch bed as a granule to discourage activities such as browsing and eating, burrowing and or digging, or general consumption or disruption of a potted plants, planting beds, landscape, garden, or other foliage environment, by animals including but not limited to, squirrels, chipmunks, prairie dogs, gophers, woodchucks, and other members of the order rodentia family not referred to herein, as well as other types of animals such as raccoons, that would otherwise destroy or damage plant material and the surrounding region or soil.

Abstract: Compositions are disclosed which have as a component thereof an inhibitor of the enzymatic production of 3-deoxyglucosone (3DG) from fructoselysine and/or an inactivator of 3DG, and which are useful for the treatment or prophylaxis of a condition or disease state that is alleviated by inhibiting such 3DG production. Methods of using such compositions, e.g., for improving the appearance, texture and/or elasticity of aging skin, are also disclosed.

Abstract: Provided is a pharmaceutical or food or drink composition for preventing or treating alcohol-induced fatty liver or steatohepatitis comprising metadoxine (pyridoxol 1-2-pyrrolidone-5-carboxylate) and garlic oil as active ingredients. The concurrent administration of metadoxine and garlic oil according to the present invention exhibits outstandingly superior effects of inhibiting the accumulation of triglyceride and increase of blood AST (aspartate aminotransferase) level in liver el tissue, inhibiting the expression of FAS (fatty acid synthase), CYP2E1 and iNOS (inducible nitric oxide synthase) and inhibiting the deactivation of AMPK (AMP-activated protein kinase), as compared to the administration of metadoxine or garlic oil only.

Abstract: The present invention includes methods and compositions for the treatment and prevention of protozoal parasitic infections utilizing Diindolylmethane-related indoles. Additive and synergistic interaction of Diindolylmethane-related indoles with other known anti-parasitic and pro-apoptotic agents is believed to permit more effective therapy and prevention of protozoal parasitic infections. The methods and compositions described provide new treatment of protozoal parasitic diseases of mammals and birds including malaria, leishmaniasis, trypanosomiasis, trichomoniasis, neosporosis and coccidiosis.

Abstract: A method of use for a topical herbal formulation alone or in combination with oral administration of niacin (preferably a flush preparation) to prevent and/or treat dyshidrosis (pompholyx) and related skin diseases. The formulation may also be used to treat contact dermatitis, eczema, palmoplantar pustulosis and skin infections incurred by invasive pathogens such as mold, fungus and bacteria. The formulation is comprised of plant extracts and niacin, that when combined yield an effective multi-faceted pharmaceutical approach to treating dry skin disorders.

Abstract: The present invention relates to a liquid preparation containing crude drug extracts in an amount of 5 to 50 w/v % in terms of a dry extract weight based on the whole amount of the liquid preparation, characterized by containing saccharides in an amount of 5 to 40 w/v % based on the whole amount of the liquid preparation and adjusting a pH to 4.5 to 5.5. This liquid preparation is suppressed in generating precipitate and suspended content with the course of time even if the crude drug extracts are contained in a high concentration and which is stable over a long period of time.

Abstract: A pesticide or repellent comprising a liquid concentrate obtained from garlic juice by the removal of water from the juice.

Abstract: The present invention provides a method for improving cognitive performance that encompasses all of: sense; perception; recognition; judgment; and action or suppression; and is based on a higher brain function. The method for improving cognitive performance of the present invention includes administering astaxanthin and/or an ester thereof to an individual. The cognitive performance is, for example, at least one selected from the group consisting of judging ability, spatial attention-allocating ability, concentration on the recognition of surroundings, and agility as determined by speed and/or accuracy of a body reaction which requires a higher brain function.

Abstract: The present invention relates to an antibacterial composition including a fermented garlic solution that is fermented by lactic acid bacteria. More specifically, it provides an antibacterial substance active against gram-positive and gram-negative bacteria, yeast, and antibiotic-resistant bacteria. An antibacterial composition according to the present invention that includes a fermented garlic solution that is fermented by lactic acid bacteria as an active ingredient controls the growth of bacteria or fungi, and is thereby able to prevent and treat infections thereof.

Abstract: The invention provides extracts and preparations based on the species Tulbaghia violacea (Harv.) (wild garlic), which elicits a significant antimicrobial, preferably antifungal activity in vitro and in vivo, even under field and glasshouse conditions. Moreover, these extracts deriving from the soil parts as well as of the aerial parts of the plant elicit a significant bio-stimulatory activity, expressed, above all, by an increased growth metabolism supporting seed growth. Furthermore, combined extracts or preparations from Tulbaghia violacea and species of the genus Agapanthus show a higher antifungal and bio-stimulatory efficacy as compared to the extracts or preparations of the single species, indicating that synergism is participated in the involved biological processes.

Abstract: A Phytoceutical composition for the prevention and treatment of hyperlipidemia—cholesterol and triglyceride disorder—is provided. A specific combination of extracts of plants and nutraceuticals is taught, as well as principles for varying the formulations based on categorizing plants and nutraceuticals into one of three groups, Energy, Bio-Intelligence, and Organization and selecting several plants and nutraceuticals from each group. Such combinations have synergistic effects, with minimal side effects.

Abstract: Extracts from plant material, or semi-purified/purified molecules or compounds prepared from the extracts that demonstrate the ability to modulate one or more cellular activities are provided. The extracts are capable of slowing down, inhibiting or preventing cell migration, for example, the migration of endothelial cells or neoplastic cells and thus, the use of the extracts to slow down, inhibit or prevent abnormal cell migration in an animal is also provided. Methods of selecting and preparing the plant extracts and methods of screening the extracts to determine their ability to modulate one or more cellular activity are described. The purification or semi-purification of one or more molecules from the described extracts is also contemplated as well as the use of these molecules, alone or in combination with an extract, to slow down, inhibit or prevent abnormal cell migration in an animal.

Abstract: There has been a demand in the marketplace for medicines, functional foods and so on which can relieve subjective symptoms of fatigue in persons having these subjective symptoms, and enabling the persons to have productive days. That is, an object of the present invention is to provide a composition for relieving subjective symptoms of fatigue. According to the present invention, a safe and effective composition for relieving subjective symptoms of fatigue which contains ornithine or a salt thereof as an active ingredient can be provided.

Abstract: Onions (Allium Cepa and its close relatives, as opposed to Allium Sativum) contain potent coagulation modulators, as well as platelet inhibitors. Clinical, in vivo and in vitro testing confirms that the efficacy of commonly consumed quantities of onions in terms of the efficacy of its impact on coagulation and platelet function rivals and in many respects exceeds the potency of any other modalities available today. Additionally, onion compounds have unique effects as described later in this application.

Abstract: A composition and method for enhancing immunity and reducing or inhibiting inflammation related innate immune system activation while affording the body of a user protection against known detrimental byproducts of immune-response is provided. The composition comprises at least a therapeutically effective amount of vitamin C and extract of Andrographis paniculata. The present invention may additionally comprise vitamin A (Retinyl palmitate), an extract of blackberry, garlic, and an extract of cranberry. A method of same is also provided.

Abstract: A non-toxic insect repellent formulation utilizing a plurality of all natural active components in solution has been proven to be effective in repelling mosquitoes for periods of between six to eight weeks, with one application. The insect repellent formulation includes a plurality of natural, essential oils in an aqueous solution comprising at least one emulsifying agent to maintain the oils in a stable solution. A pH conditioning agent may be added to assure the formulation is pH balanced for application to grass, plants, and trees, without detriment. At least one formulation includes a buoyancy agent such that the formulation floats on or at the surface of water bodies in an area of application, thereby suffocating any insect larvae as may be present there. The formulation may be provided as either a concentrate, or at dilutions ready for direct application, and may be applied by any of a variety of methods including broadcast spraying, boom applicators, misting systems, etc.

Abstract: A non-toxic insect repellent concentrate formulation utilizing a plurality of all natural active components has been proven to be effective in repelling mosquitoes for periods of between six to eight weeks, with one application. The insect repellent concentrate formulation includes a plurality of natural essential oils comprising at least one emulsifying agent to maintain the oils in a stable solution. A pH conditioning agent may be added to assure the formulation is pH balanced for application to grass, plants, and trees, without detriment. The formulation may be provided as either a concentrate, or at dilutions ready for direct application, and may be applied by any of a variety of methods including broadcast spraying, boom applicators, misting systems, aerosol spray devices, etc.

Abstract: The Federal EPA has consistently limited the use of known toxicants (insecticides) to preclude their admixture into paints and coatings by contractors or homeowners for the purpose of repelling or killing insects on the dried or cured coating. The current invention is a method to repel, rather than kill, insects, arachnids, and other arthropods, utilizing materials taken from the EPA's GRAS (Generally Recognized as Safe) List, obviating onerous Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) regulations and greatly extending the useful life of the insect-repellant materials by binding them into the dried film solids—greatly slowing their evaporation and degradation and creating a timed release of insect repellant material. Furthermore, the current invention utilizes the insect repellant nature of these materials to repel insects from the surrounding area during coating application, thereby eliminating the need for applying insect repellants, such as DEET, to the skin.

Abstract: Compositions for enhancing satiety and weight loss in an individual, assays for assessing a tastant for enhancing satiety and weight loss, and methods of using the composition to suppress appetite and enhance weight loss are provided.

Abstract: The invention relates to medicine, in particular to pharmacology, and is embodied in the form of an agent for limiting neuro-mediator, neuro-endocrine and metabolic disturbances generating the disorders of a central nervous system and functional somatic disorders. The inventive agent is based on a DSIP (delta sleep inducing peptide) or a derivative chemically related thereto and can be used for correcting and preventing functional shifts in a central nervous system and concomitant somatic disorders caused by unfavourable and extreme environmental factors and different pathological conditions of an organism or during the ageing thereof.

Abstract: Onions (Allium Cepa and its close relatives, as opposed to Allium Sativum) contain potent coagulation modulators, as well as platelet inhibitors. Clinical, in vivo and in vitro testing confirms that the efficacy of commonly consumed quantities of onions in terms of the efficacy of its impact on coagulation and platelet function rivals and in many respects exceeds the potency of any other modalities available today. Additionally, onion compounds have unique effects as described later in this application.

Abstract: Reduction of platelet counts to below 150 thousand per cubic millimeter by pharmacologic, mechanical, combined mechanical and pharmacological, or other means for the purpose of reducing the incidence and severity of vascular disease in at risk populations, for the stabilization and reversal of said disease in patients already known to suffer from such disease, as well as for the purpose of preventing and/or reducing the incidence and severity of sequelae related to such disease, whether preclinical, subclinical or overtly manifested, or whether it is presently understood to be related to said vascular disease or not.

Abstract: The disclosure provides oral compositions having at least two botanical active ingredients derived from plants. The oral composition also includes an orally acceptable vehicle to deliver an effective amount of the at least two active ingredients in vivo. The botanical active ingredients provide particularly efficacious antimicrobial (antibacterial, antiviral, and/or antifungal), antioxidant, anti-inflammatory, anti-ageing, and or healing properties to the oral compositions.

Abstract: A method of increasing pregnancy rate in a female subject is provided, the female subject or an oocyte for introduction into the female subject being fertilized by a sperm from a male subject. The method includes the steps of administering to the male subject prior to fertilization: (i) an effective amount of an anti-oxidant agent; and (ii) an effective amount of an agent that reduces inflammation in the male reproductive tract and/or an effective amount of an agent that increases testicular testosterone concentration.

Abstract: The present invention relates to compositions and methods for promoting healing of cutaneous, mucosal and/or mucocutaneous lesions associated with the presence of a mycoplasma and one or more non-mycoplasma microorganisms.

Abstract: This invention relates to products and methods for improving sensory qualities of meat obtained from livestock. In particular, this invention relates to products and methods for reducing off-odors and off-tastes in meat from uncastrated male pigs (boar taint) or from other livestock fed on pasture. According to the invention, this is obtained by administering a product that contains an inducer of the constitutive androstane receptor (CAR). These include plant products derived from Artemisia spp, Citrus spp., Gingko biloba, Tagetes lucida, as well as vitamin E (alpha tocopherol). The CAR-inducer products of the invention may be used to reduce boar taint and thereby eliminate the need for castration of male pigs.

Abstract: The present invention comprises an oral composition. More particularly to a method of treating and preventing a respiratory tract infection and providing energy, relieving stress, and mood enhancing benefits to a human comprising: the steps of administering to a human a composition comprising from about 450 IU to about 500,000 IU of cholecalciferol, per dose of the composition.

Abstract: The present invention provides multi-step methods for treating pain and/or inflammation. In a preferred embodiment, the method comprises administering to a patient in need of relief of pain and/or inflammation the following three components: (1) a skin penetration enhancer; (2) a daytime analgesic; and (3) a nighttime joint and muscle rejuvenator. The present invention also provides an analgesic composition comprising PHYTOLANE LS® and garlic oil, preferably in a cream or ointment base.

Abstract: The present invention provides a powder superior in water-dispersibility/solubility, workability and tabletability, which contains an oil component containing a bioactive substance, a water-soluble polymer, a saccharide other than polysaccharides and a surfactant, at a particular ratio. The powder can be utilized for food, food with nutrient function claims, food for specified health uses, nutritional supplement, nutritional product, animal drug, drinks, feed, pharmaceutical product, quasi-drug, cosmetic and the like.

Abstract: Two phenolic compounds occurring in nature were useful in the control of some pests. Salicylaldehyde is a substance produced by some plants and some animals. A novel pest control agent is based on salicylaldehyde. It is active against caterpillars (larvae of butterflies and moths) as well as earthworms and molluscs. In combination with garlic extract it enhances the activity of such extract. An agent for the control of insects in agriculture comprises vanillin. The vanillin powder is solubilised in water for spraying onto insects infesting crops.

Abstract: A method of providing controlled release of a biologically active substance within a subject's digestive system. The biologically active substance is administered concurrently with one or more soluble fibers in an oral dosage unit. The soluble fibers interact with the biologically active substance within the subject's digestive system to moderate and control the release of the biologically active substances in the subject's bloodstream. This provides more constant blood concentrations of the biologically active substances. The amount of soluble fibers in the oral dosage unit is greater than 40% by weight, and in some cases greater than 50% by weight of the oral dosage unit. The oral dosage unit typically contains from about 1 to 15g of soluble fiber, and in some cases from about 3 to 5g of soluble fiber. The biologically active substance may contain phytonutrients that promote the subject's cardiovascular system, immune system, or weight management.